Dennis McGonagle

Dennis McGonagle

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Dennis McGonagle

Dennis McGonagle

Publications by authors named "Dennis McGonagle"

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The simultaneous analysis of mesenchymal stem cells and early osteocytes accumulation in osteoarthritic femoral head sclerotic bone.

Rheumatology (Oxford) 2019 Oct;58(10):1777-1783

Leeds Institute of Rheumatic and Musculoskeletal Medicine, The University of Leeds.

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http://dx.doi.org/10.1093/rheumatology/kez130DOI Listing
October 2019

The role of IL-17A in axial spondyloarthritis and psoriatic arthritis: recent advances and controversies.

Ann Rheum Dis 2019 Sep 5;78(9):1167-1178. Epub 2019 Jul 5.

Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK

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http://dx.doi.org/10.1136/annrheumdis-2019-215356DOI Listing
September 2019

The relationship between physical examination and ultrasonography for large entheses is best for the Achilles tendon and patellar tendon origin.

J Rheumatol 2019 Sep 1. Epub 2019 Sep 1.

From the University of Ottawa Faculty of Medicine, Ottawa Hospital Research Institute, Department of Internal Medicine, Division of Rheumatology, Ottawa, ON, CANADA; Medeniyet University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, TURKEY; Complejo Hospitalario Torrecárdenas, Department of Internal Medicine, Division of Rheumatology, Almería, SPAIN; NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds. Leeds, UK; University of California, Department of Statistics, Riverside, California, USA; University of Toronto, Department of Internal Medicine, Division of Rheumatology, Krebmil research Institute, Toronto Western Hospital, Toronto, CANADA; University of Toronto, Women's College Research Institute, Women's College Hospital, Rheumatology, Toronto, CANADA. Address correspondence to Sibel Zehra Aydin 1967 Riverside Drive, Ottawa, ON, K1H 7W9, Canada. E-mail:

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http://www.jrheum.org/lookup/doi/10.3899/jrheum.190169
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http://dx.doi.org/10.3899/jrheum.190169DOI Listing
September 2019

Identification of senescent cells in multipotent mesenchymal stromal cell cultures: Current methods and future directions.

Cytotherapy 2019 Aug 25;21(8):803-819. Epub 2019 May 25.

Leeds Institute of Rheumatic and musculoskeletal Medicine, Leeds, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jcyt.2019.05.001DOI Listing
August 2019

The novel cytokine Metrnl/IL-41 is elevated in Psoriatic Arthritis synovium and inducible from both entheseal and synovial fibroblasts.

Clin Immunol 2019 Aug 27;208:108253. Epub 2019 Aug 27.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; National Institute for Health Research (NIHR), Leeds Biomedical Research Centre (BRC), Leeds Teaching Hospitals, Leeds, UK.

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http://dx.doi.org/10.1016/j.clim.2019.108253DOI Listing
August 2019

Response to: 'Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients' by Humby .

Ann Rheum Dis 2019 Jul 13. Epub 2019 Jul 13.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1136/annrheumdis-2019-215881DOI Listing
July 2019

Advancing research paradigms and pathophysiological pathways in psoriatic arthritis and ankylosing spondylitis: Proceedings of the 2017 Platform for the Exchange of Expertise and Research (PEER) meeting.

Semin Arthritis Rheum 2019 Jun 15;48(6):1005-1013. Epub 2018 Oct 15.

St. Vincent's University Hospital and Conway Institute for Biomolecular Research, University College Dublin School of Medicine, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.semarthrit.2018.10.008DOI Listing
June 2019

A comparison of apremilast monotherapy and combination therapy for psoriatic arthritis in a real-life setting: Data from the Leeds Combined Psoriatic Service.

J Am Acad Dermatol 2019 06 13;80(6):1796-1798. Epub 2019 Feb 13.

National Institute for Health Research Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom.

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http://dx.doi.org/10.1016/j.jaad.2019.02.014DOI Listing
June 2019

Autoimmune/inflammatory syndrome induced by adjuvants (ASIA) demonstrates distinct autoimmune and autoinflammatory disease associations according to the adjuvant subtype: Insights from an analysis of 500 cases.

Clin Immunol 2019 Jun 25;203:1-8. Epub 2019 Mar 25.

Department of Medicine 'B' and Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel; Laboratory of the Mosaics of Autoimmunity, Saint Petersburg University, Saint Petersburg, Russian Federation. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2019.03.007DOI Listing
June 2019

The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man.

Inflamm Res 2019 Jun 13;68(6):423-426. Epub 2019 Apr 13.

Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), University of Leeds, Leeds, UK.

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http://link.springer.com/10.1007/s00011-019-01235-x
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http://dx.doi.org/10.1007/s00011-019-01235-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517354PMC
June 2019

Correction to: The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man.

Inflamm Res 2019 06;68(6):427

Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1007/s00011-019-01242-yDOI Listing
June 2019

Evidence that systemic therapies for psoriasis may reduce psoriatic arthritis occurrence.

Clin Exp Rheumatol 2019 Jun 28. Epub 2019 Jun 28.

Rheumatology, University of Ottawa Faculty of Medicine, and Ottawa Hospital Research Institute (OHRI), Ottawa, Canada.

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June 2019

Ultrasonographic evidence of predominance of acute extracapsular and chronic intrasynovial patterns in 100 psoriatic hand dactylitis.

J Rheumatol 2019 May 15. Epub 2019 May 15.

Department of Clinical Medicine and Surgery, Rheumatology Research Unit, University Federico II, Naples, Italy; Department of Rheumatology, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy; Unit of Rheumatology, Ospedale Sacro Cuore, Negrar, Verona, Italy; NIHR Leeds Musculoskeletal Biomedical Research Centre, Leeds Teaching Hospitals Trust and the University of Leeds, United Kingdom; Rheumatology Unit, University of Modena and Reggio Emilia, Italy. Address correspondence to Raffaele Scarpa, MD, Full Professor, Rheumatology Unit, Department of Clinical Medicine and Surgery, University Federico II, via S. Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.3899/jrheum.190046DOI Listing
May 2019

Regression of Peripheral Subclinical Enthesopathy in Therapy-Naive Patients Treated With Ustekinumab for Moderate-to-Severe Chronic Plaque Psoriasis: A Fifty-Two-Week, Prospective, Open-Label Feasibility Study.

Arthritis Rheumatol 2019 Apr 4;71(4):626-631. Epub 2019 Mar 4.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

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http://dx.doi.org/10.1002/art.40778DOI Listing
April 2019

Systemic Sclerosis is Linked to Psoriasis and May Impact on Patients' Survival: A Large Cohort Study.

J Clin Med 2019 Apr 16;8(4). Epub 2019 Apr 16.

Department of Medicine B and Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Ramat-Gan 5265601, Israel.

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http://dx.doi.org/10.3390/jcm8040521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517892PMC
April 2019

The role of obesity on inflammation and damage in spondyloarthritis: a systematic literature review on body mass index and imaging.

Clin Exp Rheumatol 2019 Apr 29. Epub 2019 Apr 29.

Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, University of Ottawa, and Ottawa Hospital Research Institute, Ottawa, Canada.

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April 2019

The Impact of Intermittent Fasting (Ramadan Fasting) on Psoriatic Arthritis Disease Activity, Enthesitis, and Dactylitis: A Multicentre Study.

Nutrients 2019 Mar 12;11(3). Epub 2019 Mar 12.

NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, LS7 4SA Leeds, UK.

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http://dx.doi.org/10.3390/nu11030601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471071PMC
March 2019

Greater magnitude of entheseal microdamage and repair in psoriatic arthritis compared with ankylosing spondylitis on ultrasound.

Rheumatology (Oxford) 2019 Feb;58(2):299-303

Department of Internal Medicine, Division of Rheumatology, University of Ottawa Faculty of Medicine, Ottawa, ON, Canada.

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http://dx.doi.org/10.1093/rheumatology/key238DOI Listing
February 2019

The advent of IL-17A blockade in ankylosing spondylitis: secukinumab, ixekizumab and beyond.

Expert Rev Clin Immunol 2019 02 8;15(2):123-134. Epub 2019 Jan 8.

a NIHR Leeds Biomedical Research Centre , Leeds Teaching Hospitals NHS Trust , Leeds , UK.

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http://dx.doi.org/10.1080/1744666X.2019.1561281DOI Listing
February 2019

Pathophysiology, assessment and treatment of psoriatic dactylitis.

Nat Rev Rheumatol 2019 Feb;15(2):113-122

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1038/s41584-018-0147-9DOI Listing
February 2019

Comprehensive evaluation of finger flexor tendon entheseal soft tissue and bone changes by ultrasound can differentiate psoriatic arthritis and rheumatoid arthritis.

Clin Exp Rheumatol 2018 Sep-Oct;36(5):785-790. Epub 2018 Feb 28.

Rheumatology Department, Ospedale S. Maria Nuova, Reggio Emilia, Italy.

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January 2019

Arthritis Mutilans in Systemic Sclerosis.

Arthritis Rheumatol 2019 01 24;71(1):120. Epub 2018 Nov 24.

IReL, San Carlo Hospital.

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http://dx.doi.org/10.1002/art.40723DOI Listing
January 2019

The burden of depression in systemic sclerosis patients: a nationwide population-based study.

J Affect Disord 2019 01 21;243:427-431. Epub 2018 Sep 21.

Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel; Ness-Ziona, Mental Health Center, Beer-Yaakov, Israel.

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https://linkinghub.elsevier.com/retrieve/pii/S01650327183172
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http://dx.doi.org/10.1016/j.jad.2018.09.075DOI Listing
January 2019

Immunogenicity, safety and tolerability of anti-pneumococcal vaccination in systemic lupus erythematosus patients: An evidence-informed and PRISMA compliant systematic review and meta-analysis.

Autoimmun Rev 2019 Jan 5;18(1):73-92. Epub 2018 Nov 5.

Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK; Department of Medicine 'B', Sheba Medical Center, Tel-Hashomer, Israel; Zabludowicz center for Autoimmune Diseases, Sheba Medical Center, Tel-Hashomer, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Hashomer, Israel.

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https://linkinghub.elsevier.com/retrieve/pii/S15689972183026
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http://dx.doi.org/10.1016/j.autrev.2018.08.002DOI Listing
January 2019

Acute Unilateral Sacroiliitis Mimicking Infection on Magnetic Resonance Imaging with Response to Nonsteroidal Antiinflammatory Drugs: A Distinct Presentation of Spondyloarthritis?

J Rheumatol 2018 12 15;45(12):1708-1710. Epub 2018 Aug 15.

NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.3899/jrheum.171456DOI Listing
December 2018

A Novel Arthroscopic Technique for Intraoperative Mobilization of Synovial Mesenchymal Stem Cells.

Am J Sports Med 2018 12 12;46(14):3532-3540. Epub 2018 Nov 12.

Faculty of Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, West Yorkshire, UK.

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http://dx.doi.org/10.1177/0363546518803757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282154PMC
December 2018

Mechanistic immunological based classification of rheumatoid arthritis.

Autoimmun Rev 2018 Nov 11;17(11):1115-1123. Epub 2018 Sep 11.

Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, United Kingdom.

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http://dx.doi.org/10.1016/j.autrev.2018.06.001DOI Listing
November 2018

The Early Phases of Ankylosing Spondylitis: Emerging Insights From Clinical and Basic Science.

Front Immunol 2018 16;9:2668. Epub 2018 Nov 16.

Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, United Kingdom.

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02668
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http://dx.doi.org/10.3389/fimmu.2018.02668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250731PMC
November 2018

Spondyloarthritis: new insights into clinical aspects, translational immunology and therapeutics.

Curr Opin Rheumatol 2018 09;30(5):526-532

Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK.

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http://dx.doi.org/10.1097/BOR.0000000000000529DOI Listing
September 2018

T cell immunomodulation by clinically used allogeneic human cancellous bone fragments: a potential novel immunotherapy tool.

Sci Rep 2018 09 10;8(1):13535. Epub 2018 Sep 10.

National Institute of Health Research Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

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http://www.nature.com/articles/s41598-018-31979-1
Publisher Site
http://dx.doi.org/10.1038/s41598-018-31979-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131386PMC
September 2018

Hidradenitis suppurativa as an autoinflammatory keratinization disease.

J Allergy Clin Immunol 2018 05 2;141(5):1953. Epub 2018 Mar 2.

Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, Leeds, United Kingdom; NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals, Leeds, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749183013
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http://dx.doi.org/10.1016/j.jaci.2018.01.010DOI Listing
May 2018

Enthesitis: Much More Than Focal Insertion Point Inflammation.

Curr Rheumatol Rep 2018 05 30;20(7):41. Epub 2018 May 30.

Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds, NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK.

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http://dx.doi.org/10.1007/s11926-018-0751-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976708PMC
May 2018

Platelet lysate enhances synovial fluid multipotential stromal cells functions: Implications for therapeutic use.

Cytotherapy 2018 03 3;20(3):375-384. Epub 2018 Feb 3.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds, United Kingdom.

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http://dx.doi.org/10.1016/j.jcyt.2017.12.003DOI Listing
March 2018

New advances in the understanding and treatment of axial spondyloarthritis: from chance to choice.

Ther Adv Chronic Dis 2018 Mar 14;9(3):77-87. Epub 2017 Dec 14.

NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

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http://dx.doi.org/10.1177/2040622317743486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833172PMC
March 2018

Short-term Repeat Magnetic Resonance Imaging Scans in Suspected Early Axial Spondyloarthritis Are Clinically Relevant Only in HLA-B27-positive Male Subjects.

J Rheumatol 2018 02 1;45(2):202-205. Epub 2017 Dec 1.

From the Royal National Hospital for Rheumatic Diseases, Bath; UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals Trust; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds; Culture and Environment College of Liberal Arts, Bath Spa University, Bath; Academic Department of Military Rehabilitation, Defence Medical Rehabilitation Centre, Headley Court, Epsom; University of Bath, Bath, UK.

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http://dx.doi.org/10.3899/jrheum.170171DOI Listing
February 2018

The problem in differentiation between psoriatic-related polyenthesitis and fibromyalgia.

Rheumatology (Oxford) 2018 01;57(1):32-40

NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals Trust.

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http://dx.doi.org/10.1093/rheumatology/kex079DOI Listing
January 2018

Minimal Disease Activity as a Treatment Target in Psoriatic Arthritis: A Review of the Literature.

J Rheumatol 2018 01 15;45(1):6-13. Epub 2017 Nov 15.

From Sorbonne Universités, UPMC Univ Paris 06; Department of Rheumatology, AP-HP, Pitié Salpêtrière Hospital, Paris, France; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and UK National Institute for Health Research (NIHR) Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK; V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia; Dipartimento di Medicina e Scienze della Salute, Università degli Studi del Molise, Campobasso, Italy; Hospital Universitario La Paz, Rheumatology Department, Madrid, Spain; Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark; Rheumatology University Hospital Frankfurt and Project Group Translational Medicine and Pharmacology TMP, Fraunhofer Institute for Molecular Biology and Applied Ecology IME, Goethe University Frankfurt am Main, Frankfurt, Germany.

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http://dx.doi.org/10.3899/jrheum.170449DOI Listing
January 2018

A survey of anatomical items relevant to the practice of rheumatology: pelvis, lower extremity, and gait.

Clin Rheumatol 2017 Dec 1;36(12):2813-2819. Epub 2017 Jun 1.

Hospital de Especialidades Dr. Antonio Fraga Mouret, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Mexico City, Mexico.

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http://dx.doi.org/10.1007/s10067-017-3702-xDOI Listing
December 2017

Native joint-resident mesenchymal stem cells for cartilage repair in osteoarthritis.

Nat Rev Rheumatol 2017 Dec 9;13(12):719-730. Epub 2017 Nov 9.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Chapel Allerton Hospital, Chapeltown Road, Leeds LS7 4SA, UK.

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http://dx.doi.org/10.1038/nrrheum.2017.182DOI Listing
December 2017

Vascularity of nail bed by ultrasound to discriminate psoriasis, psoriatic arthritis and healthy controls.

Clin Exp Rheumatol 2017 Sep-Oct;35(5):872. Epub 2017 Jun 16.

Section of Musculoskeletal Disease, Leeds Institute of Molecular Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals, UK.

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November 2017

Polymyalgia rheumatica development in a patient under PI3K inhibitor therapy for chronic lymphocytic leukaemia.

BMJ Case Rep 2017 Nov 8;2017. Epub 2017 Nov 8.

NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1136/bcr-2017-221065DOI Listing
November 2017

Targeting subchondral bone mesenchymal stem cell activities for intrinsic joint repair in osteoarthritis.

Future Sci OA 2017 Nov 6;3(4):FSO228. Epub 2017 Sep 6.

Leeds Institute of Rheumatic & Musculoskeletal Medicine, The University of Leeds, Leeds, UK.

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http://dx.doi.org/10.4155/fsoa-2017-0055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674229PMC
November 2017

Enthesitis: from pathophysiology to treatment.

Nat Rev Rheumatol 2017 Nov;13(12):731-741

Section of Musculoskeletal Diseases, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and Chapel Allerton Hospital, Chapeltown Road, Leeds, West Yorkshire LS7 4SA, UK.

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http://dx.doi.org/10.1038/nrrheum.2017.188DOI Listing
November 2017

Autoimmune-autoinflammatory rheumatoid arthritis overlaps: a rare but potentially important subgroup of diseases.

RMD Open 2017 1;3(2):e000550. Epub 2017 Nov 1.

Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, St James's University Hospital, Leeds, UK.

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http://dx.doi.org/10.1136/rmdopen-2017-000550DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5687541PMC
November 2017

Lessons Learned from Imaging on Enthesitis in Psoriatic Arthritis.

Isr Med Assoc J 2017 Nov;19(11):708-711

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton.

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November 2017

Reply to: Behçet's disease: an MHC-I-opathy?

Clin Exp Rheumatol 2017 May-Jun;35 Suppl 104(2). Epub 2017 Apr 14.

Department of Internal Medicine, Division of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey.

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September 2017

Brief Report: Group 3 Innate Lymphoid Cells in Human Enthesis.

Arthritis Rheumatol 2017 09 8;69(9):1816-1822. Epub 2017 Aug 8.

University of Leeds and NIHR-Leeds Musculoskeletal and Biomedical Research Unit, Leeds Teaching Hospital Trust, Leeds, UK.

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http://dx.doi.org/10.1002/art.40150DOI Listing
September 2017

Development and Reliability of a Preliminary Foot Osteoarthritis Magnetic Resonance Imaging Score.

J Rheumatol 2017 08 1;44(8):1257-1264. Epub 2017 Jun 1.

From the Leeds Institute of Rheumatic and Musculoskeletal Medicine, and the School of Healthcare, University of Leeds; UK National Institute for Health Research (NIHR) Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds; Arthritis Research UK Experimental Osteoarthritis Treatment Centre, Leeds; Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Nottingham/Leeds; Salford Royal Hospital UK National Health Service (NHS) Foundation Trust, Manchester, UK; Department of Musculoskeletal Radiology, La Paz University Hospital, Autonomous University of Madrid; Biomedical Research Networking Centre on Bioengineering, Biomaterials and Nanomedicine, Madrid, Spain.

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http://dx.doi.org/10.3899/jrheum.160617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544115PMC
August 2017

The CD45lowCD271high Cell Prevalence in Bone Marrow Samples May Provide a Useful Measurement of the Bone Marrow Quality for Cartilage and Bone Regenerative Therapy.

J Bone Joint Surg Am 2017 Aug;99(15):1305-1313

1Leeds Institute of Rheumatic and Musculoskeletal Medicine, St. James Hospital, University of Leeds, Leeds, United Kingdom 2NIHR-Leeds Musculoskeletal Biomedical Research Unit (LMBRU), Chapel Allerton Hospital, University of Leeds, Leeds, United Kingdom 3Clinical Pathology Department, Mansoura University, Mansoura, Egypt.

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http://dx.doi.org/10.2106/JBJS.16.01138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125756PMC
August 2017

Early Emergence of CD19-Negative Human Antibody-Secreting Cells at the Plasmablast to Plasma Cell Transition.

J Immunol 2017 06 10;198(12):4618-4628. Epub 2017 May 10.

Section of Experimental Haematology, Leeds Institute of Cancer and Pathology, University of Leeds, Leeds LS9 7TF, United Kingdom; and

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http://dx.doi.org/10.4049/jimmunol.1501761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5458329PMC
June 2017

An educational leaflet improves response to invitation for screening for arthritis in patients with psoriasis in primary care, but only in practices in the most deprived areas.

Clin Rheumatol 2017 Mar 15;36(3):719-723. Epub 2016 Dec 15.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2nd Floor, Chapel Allerton Hospital, Harehills Lane, Leeds, LS7 4SA, UK.

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http://dx.doi.org/10.1007/s10067-016-3503-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323500PMC
March 2017

Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γ.

Proc Natl Acad Sci U S A 2017 03 13;114(13):E2748-E2757. Epub 2017 Mar 13.

School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, United Kingdom;

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http://dx.doi.org/10.1073/pnas.1620954114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380102PMC
March 2017

Predicting the Remaining Lifespan and Cultivation-Related Loss of Osteogenic Capacity of Bone Marrow Multipotential Stromal Cells Applicable across a Broad Donor Age Range.

Stem Cells Int 2017 19;2017:6129596. Epub 2017 Feb 19.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Beckett Street, Leeds LS9 7TF, UK; NIHR Research Unit, Chapel Allerton Hospital, Leeds Teaching Hospital NHS Trust, Chapeltown Road, Leeds LS7 4SA, UK.

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http://dx.doi.org/10.1155/2017/6129596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5337353PMC
February 2017

Mesenchymal Stem Cell Alterations in Bone Marrow Lesions in Patients With Hip Osteoarthritis.

Arthritis Rheumatol 2016 07;68(7):1648-59

University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK.

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http://dx.doi.org/10.1002/art.39622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4941540PMC
July 2016

Evidence of response to IL-6 inhibition in some cases of refractory spondyloarthritis-associated peripheral synovitis.

Ann Rheum Dis 2016 07 8;75(7):1418-20. Epub 2016 Apr 8.

NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, UK Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1136/annrheumdis-2016-209275DOI Listing
July 2016

Synovial fluid hyaluronan mediates MSC attachment to cartilage, a potential novel mechanism contributing to cartilage repair in osteoarthritis using knee joint distraction.

Ann Rheum Dis 2016 May 6;75(5):908-15. Epub 2015 May 6.

Faculty of Medicine, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, West Yorkshire, UK NIHR-Leeds Musculoskeletal and Biomedical Research Unit, Chapel Allerton, Leeds Teaching Hospital Trust, Leeds, West Yorkshire, UK.

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http://dx.doi.org/10.1136/annrheumdis-2014-206847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853581PMC
May 2016

Anakinra as a diagnostic challenge and treatment option for systemic autoinflammatory disorders of undefined etiology.

JCI Insight 2016 05 5;1(6):e86336. Epub 2016 May 5.

NIH Research-Leeds Musculoskeletal Biomedical Research Unit (NIHR-LMBRU) and Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), Wellcome Trust Brenner Building, St. James's University Hospital, Beckett Street, Leeds, United Kingdom.

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https://insight.jci.org/articles/view/86336
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http://dx.doi.org/10.1172/jci.insight.86336DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033915PMC
May 2016

Response to: 'A relationship between extracapsular involvement and response to steroid treatment in polymyalgia rheumatica: too soon to conclude?' by Yang et al.

Ann Rheum Dis 2016 Apr 27;75(4):e17. Epub 2016 Jan 27.

University of Leeds. Leeds Institute of Rheumatic and Musculoskeletal Medicine, Chapel Allerton Hospital, Leeds, UK.

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http://dx.doi.org/10.1136/annrheumdis-2015-208962DOI Listing
April 2016

Neutrophil Elastase-mediated proteolysis activates the anti-inflammatory cytokine IL-36 Receptor antagonist.

Sci Rep 2016 04 22;6:24880. Epub 2016 Apr 22.

Leeds Institute of Rheumatic and Musculoskeletal Medicine (LIRMM), University of Leeds, UK.

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http://dx.doi.org/10.1038/srep24880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840362PMC
April 2016

The Need for Biological Outcomes for Biological Drugs in Psoriatic Arthritis.

J Rheumatol 2016 Jan;43(1):3-6

Professor in Regenerative Medicine, UK National Institute for Health Research Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.3899/jrheum.151296DOI Listing
January 2016

Whole-body MRI of patients with polymyalgia rheumatica identifies a distinct subset with complete patient-reported response to glucocorticoids.

Ann Rheum Dis 2015 Dec 16;74(12):2188-92. Epub 2015 Sep 16.

Leeds Institute for Rheumatic and Musculoskeletal Medicine, Leeds, UK NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds, UK.

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http://dx.doi.org/10.1136/annrheumdis-2015-207395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4680120PMC
December 2015

The enthesis in psoriatic arthritis.

Clin Exp Rheumatol 2015 Sep-Oct;33(5 Suppl 93):S36-9. Epub 2015 Oct 15.

NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital; and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

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December 2015

'MHC-I-opathy'-unified concept for spondyloarthritis and Behçet disease.

Nat Rev Rheumatol 2015 12 3;11(12):731-40. Epub 2015 Nov 3.

Marmara University, School of Medicine, Department of Internal Medicine, Division of Rheumatology, Mimar Sinan Caddesi 41, Pendik, 34890, Istanbul, Turkey.

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http://dx.doi.org/10.1038/nrrheum.2015.147DOI Listing
December 2015

Limited ultrasound protocol of the Achilles enthesis.

Rheumatology (Oxford) 2015 Sep 10;54(9):1539-40. Epub 2015 Jul 10.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1093/rheumatology/kev233DOI Listing
September 2015

Ustekinumab in the Treatment of Psoriasis and Psoriatic Arthritis.

Rheumatol Ther 2015 Jun 17;2(1):1-16. Epub 2015 Mar 17.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1007/s40744-015-0010-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4883251PMC
June 2015

Unifocal psoriatic arthritis development in identical twins following site specific injury: evidence supporting biomechanical triggering events in genetically susceptible hosts.

Ann Rheum Dis 2015 May 28;74(5):948-9. Epub 2015 Jan 28.

NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1136/annrheumdis-2014-206784DOI Listing
May 2015

Tocilizumab-induced psoriasiform rash in rheumatoid arthritis.

Dermatology 2014 12;228(4):311-3. Epub 2014 Jun 12.

Rheumatology Division, Hospital General de Almansa, Almansa, Spain.

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http://dx.doi.org/10.1159/000362266DOI Listing
April 2015

Musculoskeletal biology and bioengineering. A new in vivo stem cell model for regenerative rheumatology.

Nat Rev Rheumatol 2015 Apr 3;11(4):200-1. Epub 2015 Mar 3.

The Mesenchymal Stem Cell Group, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Beckett Street, Leeds LS9 7TF, UK.

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http://dx.doi.org/10.1038/nrrheum.2015.21DOI Listing
April 2015

Differentiation between osteoarthritis and psoriatic arthritis: implications for pathogenesis and treatment in the biologic therapy era.

Rheumatology (Oxford) 2015 Jan 16;54(1):29-38. Epub 2014 Sep 16.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK and Department of Radiology, Charité Medical School, Berlin, Germany. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK and Department of Radiology, Charité Medical School, Berlin, Germany.

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http://dx.doi.org/10.1093/rheumatology/keu328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269795PMC
January 2015

High-resolution MRI assessment of dactylitis in psoriatic arthritis shows flexor tendon pulley and sheath-related enthesitis.

Ann Rheum Dis 2015 Jan 26;74(1):185-9. Epub 2014 Sep 26.

NIHR Leeds Musculoskeletal Biomedical Research Unit, Chapel Allerton Hospital, Leeds, UK Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK Faculty of Medicine, Department of Radiology, Shimane University, Japan Department of Medical Physics and Engineering, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

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http://dx.doi.org/10.1136/annrheumdis-2014-205839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283670PMC
January 2015

Screening psoriatic arthritis tools: analysis of the Early Arthritis for Psoriatic Patients questionnaire.

Rheumatology (Oxford) 2015 Jan 3;54(1):200-2. Epub 2014 Nov 3.

Department of Rheumatology, Hospital General de Granollers, Granollers, Spain, Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals, Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK. Department of Rheumatology, Hospital General de Granollers, Granollers, Spain, Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals, Leeds, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK.

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http://dx.doi.org/10.1093/rheumatology/keu426DOI Listing
January 2015

The systemic influence of platelet-derived growth factors on bone marrow mesenchymal stem cells in fracture patients.

BMC Med 2015 Jan 13;13. Epub 2015 Jan 13.

NIHR Leeds Biomedical Research Unit, Chapel Allerton Hospital, Leeds West Yorkshire, Leeds LS7 4SA, UK.

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http://dx.doi.org/10.1186/s12916-014-0202-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4293103PMC
January 2015

Prolonged remission of marginal zone lymphoma in a patient with rheumatoid arthritis treated with anti-tumor necrosis factor agents.

J Rheumatol 2014 Dec;41(12):2496-7

University of Leeds, and Honorary NHS Consultant, Leeds Teaching Hospitals NHS Trust, Leeds, UK.

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http://dx.doi.org/10.3899/jrheum.140725DOI Listing
December 2014

The role of mechanical stress in the pathogenesis of spondyloarthritis and how to combat it.

Best Pract Res Clin Rheumatol 2014 Oct 22;28(5):703-10. Epub 2014 Nov 22.

The Leeds Institute of Rheumatic and Musculoskeletal Medicine, 2nd Floor, Chapel Allerton Hospital, Chapeltown Road, Leeds LS7 4SA, UK. Electronic address:

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http://dx.doi.org/10.1016/j.berh.2014.10.009DOI Listing
October 2014

The assessment of CD146-based cell sorting and telomere length analysis for establishing the identity of mesenchymal stem cells in human umbilical cord.

F1000Res 2014 11;3:126. Epub 2014 Jun 11.

Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, LS97TF, UK ; NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, LS97TF, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162508PMC
http://dx.doi.org/10.12688/f1000research.4260.2DOI Listing
September 2014

Cytokines as therapeutic targets in skin inflammation.

Cytokine Growth Factor Rev 2014 Aug 1;25(4):443-51. Epub 2014 Aug 1.

Department for Dermatology and Allergy, Hannover Medical School, Carl-Neuberg-Str 1, 30625 Hannover, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cytogfr.2014.07.008DOI Listing
August 2014