Publications by authors named "Dennis M Whitfield"

30Publications

Total Biosynthesis of Legionaminic Acid, a Bacterial Sialic Acid Analogue.

Angew Chem Int Ed Engl 2016 09 19;55(39):12018-21. Epub 2016 Aug 19.

Department of Chemistry and Biomolecular Sciences, Centre for Chemical and Synthetic Biology, University of Ottawa, Ottawa, ON, K1N 6N5, Canada.

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http://dx.doi.org/10.1002/anie.201606006DOI Listing
September 2016

General low-temperature reaction pathway from precursors to monomers before nucleation of compound semiconductor nanocrystals.

Nat Commun 2016 08 17;7:12223. Epub 2016 Aug 17.

Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610065, China.

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http://dx.doi.org/10.1038/ncomms12223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992053PMC
August 2016

Insights into the Mechanistic Role of Diphenylphosphine Selenide, Diphenylphosphine, and Primary Amines in the Formation of CdSe Monomers.

J Phys Chem A 2016 Feb 5;120(6):918-31. Epub 2016 Feb 5.

College of Chemical Engineering, ‡Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, and §College of Physics, Sichuan University , Chengdu, Sichuan 610064, People's Republic of China.

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http://dx.doi.org/10.1021/acs.jpca.5b10675DOI Listing
February 2016

In a glycosylation reaction how does a hydroxylic nucleophile find the activated anomeric carbon?

Carbohydr Res 2015 Feb 5;403:69-89. Epub 2014 Jun 5.

National Research Council, Human Health Therapeutics, 100 Sussex Drive, Ottawa, ON K1A 0R6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.carres.2014.05.021DOI Listing
February 2015

Mechanistic study of the role of primary amines in precursor conversions to semiconductor nanocrystals at low temperature.

Angew Chem Int Ed Engl 2014 Jul 22;53(27):6898-904. Epub 2014 May 22.

Key Laboratory of Green Chemistry and Technology, Ministry of Education, Sichuan University, Chengdu 610065 (P. R. China); National Research Council of Canada, Ottawa, ON, K1A 0R6 (Canada).

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http://dx.doi.org/10.1002/anie.201403714DOI Listing
July 2014

Complications of modeling glycosylation reactions: can the anomeric conformation of a donor determine the glycopyranosyl oxacarbenium ring conformation?

Carbohydr Res 2012 Jul 11;356:191-5. Epub 2012 Apr 11.

National Research Council, Institute for Biological Sciences, 100 Sussex Drive, Ottawa, ON, Canada K1A 0R6.

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https://linkinghub.elsevier.com/retrieve/pii/S00086215120016
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http://dx.doi.org/10.1016/j.carres.2012.04.001DOI Listing
July 2012

Plausible Transition States for glycosylation reactions.

Carbohydr Res 2012 Jul 6;356:180-90. Epub 2012 Apr 6.

National Research Council, Institute for Biological Sciences, 100 Sussex Drive, Ottawa, ON, Canada K1A 0R6.

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http://dx.doi.org/10.1016/j.carres.2012.03.040DOI Listing
July 2012

Could diastereoselectivity in the presence of O-2 chiral nonparticipating groups be an indicator of glycopyranosyl oxacarbenium ions in glycosylation reactions?

J Org Chem 2012 Apr 2;77(8):3724-39. Epub 2012 Apr 2.

National Research Council, Institute for Biological Sciences, 100 Sussex Drive, Ottawa, Ontario, Canada K1A 0R6.

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http://dx.doi.org/10.1021/jo202563fDOI Listing
April 2012

Isopranoid- and dipalmitoyl-aminophospholipid adjuvants impact differently on longevity of CTL immune responses.

J Liposome Res 2010 Dec 11;20(4):304-14. Epub 2010 Feb 11.

National Research Council, Institute for Biological Sciences, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.3109/08982100903544151DOI Listing
December 2010

Development of new glycosylation methodologies for the synthesis of archaeal-derived glycolipid adjuvants.

Carbohydr Res 2010 Jan 6;345(2):214-29. Epub 2009 Nov 6.

National Research Council, Institute for Biological Science, 100 Sussex Drive, Ottawa, Canada ON K1A 0R6.

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http://dx.doi.org/10.1016/j.carres.2009.10.011DOI Listing
January 2010

Computational studies of the role of glycopyranosyl oxacarbenium ions in glycobiology and glycochemistry.

Adv Carbohydr Chem Biochem 2009 ;62:83-159

Institute for Biological Sciences, National Research Council of Canada, Ottawa, Ontario, Canada

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http://dx.doi.org/10.1016/S0065-2318(09)00004-3DOI Listing
July 2009

The CMP-legionaminic acid pathway in Campylobacter: biosynthesis involving novel GDP-linked precursors.

Glycobiology 2009 Jul 12;19(7):715-25. Epub 2009 Mar 12.

Institute for Biological Sciences, National Research Council, Ottawa, Ontario, K1A 0R6 Canada.

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https://academic.oup.com/glycob/article-lookup/doi/10.1093/g
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http://dx.doi.org/10.1093/glycob/cwp039DOI Listing
July 2009

Synthesis of archaeal glycolipid adjuvants-what is the optimum number of sugars?

Carbohydr Res 2008 Sep 4;343(14):2349-60. Epub 2008 Jul 4.

National Research Council, Institute for Biological Sciences, 100 Sussex Drive Ottawa, ON, Canada K1A 0R6.

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http://dx.doi.org/10.1016/j.carres.2008.06.021DOI Listing
September 2008

Adjuvant potential of archaeal synthetic glycolipid mimetics critically depends on the glyco head group structure.

Glycobiology 2008 Jul 1;18(7):559-65. Epub 2008 May 1.

National Research Council of Canada, Institute for Biological Sciences, 100 Sussex Drive, Ottawa, Ontario K1A 0R6, Canada.

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https://academic.oup.com/glycob/article-lookup/doi/10.1093/g
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http://dx.doi.org/10.1093/glycob/cwn038DOI Listing
July 2008

O-2 Substituted pyranosyl oxacarbenium ions are C-2-O-2 2-fold rotors with a strong syn preference.

Carbohydr Res 2007 Dec 29;342(18):2793-800. Epub 2007 Sep 29.

Steacie Institute for Molecular Sciences, NRC Canada, 100 Sussex Drive, Ottawa, ON, Canada K1A 0R6.

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http://dx.doi.org/10.1016/j.carres.2007.09.007DOI Listing
December 2007

DFT studies of the ionization of alpha and beta glycopyranosyl donors.

Carbohydr Res 2007 Sep 18;342(12-13):1726-40. Epub 2007 May 18.

Institute for Biological Sciences, NRC Canada, 100 Sussex Drive, Ottawa, ON, Canada K1A 0R6.

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http://dx.doi.org/10.1016/j.carres.2007.05.012DOI Listing
September 2007

DFT studies of the role of C-2-O-2 bond rotation in neighboring-group glycosylation reactions.

Carbohydr Res 2007 Jul 14;342(10):1291-304. Epub 2007 Apr 14.

Institute for Biological Sciences, NRC Canada, 100 Sussex Drive, Ottawa, ON, Canada.

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http://dx.doi.org/10.1016/j.carres.2007.03.030DOI Listing
July 2007

Investigations into the role of oxacarbenium ions in glycosylation reactions by ab initio molecular dynamics.

Carbohydr Res 2006 Dec 12;341(18):2912-20. Epub 2006 Oct 12.

Steacie Institute for Molecular Sciences, NRC Canada, 100 Sussex Drive, Ottawa, Ont., Canada.

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http://dx.doi.org/10.1016/j.carres.2006.09.027DOI Listing
December 2006

Conformational pathways of saturated six-membered rings. A static and dynamical density functional study.

J Phys Chem A 2005 Sep;109(36):8096-105

Steacie Institute for Molecular Sciences, National Research Council of Canada, Theory and Computation Program, 100 Sussex Drive, Ottawa, Ontario K1A 0R6, Canada.

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http://dx.doi.org/10.1021/jp052197tDOI Listing
September 2005

The two-conformer hypothesis: 2,3,4,6-tetra-O-methyl-mannopyranosyl and -glucopyranosyl oxacarbenium ions.

Carbohydr Res 2005 Apr;340(5):841-52

The Institute for Physical and Chemical Research (RIKEN), Wako-shi, 351-01 Saitama, Japan.

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http://dx.doi.org/10.1016/j.carres.2004.12.021DOI Listing
April 2005

A selective Sc(OTf)3-catalyzed trialkylsilyl ether to acetyl ester exchange reaction with beta-l-idopyranoside and 3,4-O-isopropylidene-beta-D-galactopyranoside derivatives.

Carbohydr Res 2004 Dec;339(18):2841-50

Institute for Biological Sciences, National Research Council, Ottawa, Canada ON K1A 0R6.

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http://dx.doi.org/10.1016/j.carres.2004.10.006DOI Listing
December 2004

Simplifying oligosaccharide synthesis: efficient synthesis of lactosamine and siaylated lactosamine oligosaccharide donors.

J Org Chem 2003 Mar;68(6):2426-31

Institute for Biological Sciences, National Research Council of Canada, 100 Sussex Drive, Room 3024, Ottawa, Ontario, K1A 0R6, Canada.

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http://dx.doi.org/10.1021/jo026569vDOI Listing
March 2003

Can the stereochemical outcome of glycosylation reactions be controlled by the conformational preferences of the glycosyl donor?

Carbohydr Res 2002 Apr;337(8):765-74

The Institute for Physical and Chemical Research (RIKEN), Wako-shi, 351-01 Saitama, Japan.

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http://dx.doi.org/10.1016/s0008-6215(02)00043-5DOI Listing
April 2002