Denise Treue

Immune-related gene expression predicts response to neoadjuvant chemotherapy but not additional benefit from PD-L1 inhibition in women with early triple-negative breast cancer.

Clin Cancer Res 2021 Feb 16. Epub 2021 Feb 16.

Institute of Pathology, Philipps-University Marburg and University Hospital Marburg

February 2021

TFE3 activation in a TSC1-altered malignant PEComa: challenging the dichotomy of the underlying pathogenic mechanisms.

Authors:

Maren Schmiester Anna Dolnik Uwe Kornak Berit Pfitzner Michael Hummel Denise Treue Arndt Hartmann Abbas Agaimy Veronika Weyerer Anja Lekaj Susanne Brakemeier Robert Peters Robert Öllinger Sven Märdian Lars Bullinger Jana Käthe Striefler Anne Flörcken

J Pathol Clin Res 2021 01 12;7(1):3-9. Epub 2020 Nov 12.

Department of Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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January 2021

Multiclass cancer classification in fresh frozen and formalin-fixed paraffin-embedded tissue by DigiWest multiplex protein analysis.

Authors:

Teresa Bockmayr Gerrit Erdmann Denise Treue Philipp Jurmeister Julia Schneider Anja Arndt Daniel Heim Michael Bockmayr Christoph Sachse Frederick Klauschen

Lab Invest 2020 10 29;100(10):1288-1299. Epub 2020 Jun 29.

Institute of Pathology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.

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October 2020

Distinct immune evasion in APOBEC-enriched, HPV-negative HNSCC.

Authors:

Clemens Messerschmidt Benedikt Obermayer Konrad Klinghammer Sebastian Ochsenreither Denise Treue Albrecht Stenzinger Hanno Glimm Stefan Fröhling Thomas Kindler Christian H Brandts Klaus Schulze-Osthoff Wilko Weichert Ingeborg Tinhofer Frederick Klauschen Ulrich Keilholz Dieter Beule Damian T Rieke

Int J Cancer 2020 Oct 18;147(8):2293-2302. Epub 2020 Jun 18.

Department of Hematology and Oncology, Campus Benjamin Franklin, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Hindenburgdamm 30, Berlin, 12203, Germany.

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October 2020

Mutations Predict Sensitivity to Adjuvant Gemcitabine in Patients with Pancreatic Ductal Adenocarcinoma: Next-Generation Sequencing Results from the CONKO-001 Trial.

Authors:

Marianne Sinn Bruno V Sinn Denise Treue Ulrich Keilholz Frederik Damm Rosa Schmuck Philipp Lohneis Frederick Klauschen Jana K Striefler Marcus Bahra Hendrik Bläker Sven Bischoff Uwe Pelzer Helmut Oettle Hanno Riess Jan Budczies Carsten Denkert

Clin Cancer Res 2020 Jul 31;26(14):3732-3739. Epub 2020 Mar 31.

Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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July 2020

Next generation sequencing of lung adenocarcinoma subtypes with intestinal differentiation reveals distinct molecular signatures associated with histomorphology and therapeutic options.

Authors:

Philipp Jurmeister Claudia Vollbrecht Anke Behnke Nikolaj Frost Alexander Arnold Denise Treue Jens-Carsten Rückert Jens Neudecker Leonille Schweizer Frederick Klauschen David Horst Michael Hummel Manfred Dietel Maximilian von Laffert

Lung Cancer 2019 12 11;138:43-51. Epub 2019 Oct 11.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Institute of Pathology, Berlin, Germany; German Cancer Consortium (DKTK), Partner Site Berlin, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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December 2019

Machine learning analysis of DNA methylation profiles distinguishes primary lung squamous cell carcinomas from head and neck metastases.

Authors:

Philipp Jurmeister Michael Bockmayr Philipp Seegerer Teresa Bockmayr Denise Treue Grégoire Montavon Claudia Vollbrecht Alexander Arnold Daniel Teichmann Keno Bressem Ulrich Schüller Maximilian von Laffert Klaus-Robert Müller David Capper Frederick Klauschen

Sci Transl Med 2019 09;11(509)

Institute of Pathology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, 10117 Berlin, Germany.

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September 2019

Mutational Diversity and Therapy Response in Breast Cancer: A Sequencing Analysis in the Neoadjuvant GeparSepto Trial.

Clin Cancer Res 2019 07 12;25(13):3986-3995. Epub 2019 Apr 12.

Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Berlin, Germany.

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July 2019

Proteogenomic systems analysis identifies targeted therapy resistance mechanisms in EGFR-mutated lung cancer.

Authors:

Denise Treue Michael Bockmayr Albrecht Stenzinger Daniel Heim Svenja Hester Frederick Klauschen

Int J Cancer 2019 02 8;144(3):545-557. Epub 2018 Nov 8.

Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Institute of Pathology, Berlin, Germany.

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February 2019

Sphingosine Kinase 1 Regulates Inflammation and Contributes to Acute Lung Injury in Pneumococcal Pneumonia via the Sphingosine-1-Phosphate Receptor 2.

Crit Care Med 2018 03;46(3):e258-e267

Department of Infectious Diseases and Pulmonary Medicine, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

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March 2018

Multilayered Omics-Based Analysis of a Head and Neck Cancer Model of Cisplatin Resistance Reveals Intratumoral Heterogeneity and Treatment-Induced Clonal Selection.

Authors:

Franziska Niehr Theresa Eder Tanja Pilz Robert Konschak Denise Treue Frederick Klauschen Michael Bockmayr Seval Türkmen Korinna Jöhrens Volker Budach Ingeborg Tinhofer

Clin Cancer Res 2018 01 23;24(1):158-168. Epub 2017 Oct 23.

Charité, Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Radiooncology and Radiotherapy, Berlin, Germany.

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January 2018

Ioncopy: a novel method for calling copy number alterations in amplicon sequencing data including significance assessment.

Authors:

Jan Budczies Nicole Pfarr Albrecht Stenzinger Denise Treue Volker Endris Fakher Ismaeel Nikola Bangemann Jens-Uwe Blohmer Manfred Dietel Sibylle Loibl Frederick Klauschen Wilko Weichert Carsten Denkert

Oncotarget 2016 Mar;7(11):13236-47

Institute of Pathology, Charité University Hospital, Berlin, Germany.

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March 2016

Comparison of targeted next-generation sequencing and Sanger sequencing for the detection of PIK3CA mutations in breast cancer.

Authors:

Ruza Arsenic Denise Treue Annika Lehmann Michael Hummel Manfred Dietel Carsten Denkert Jan Budczies

BMC Clin Pathol 2015 18;15:20. Epub 2015 Nov 18.

Institute of Pathology, Charité University Hospital Berlin, Berlin, Germany.

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November 2015

Semiconductor sequencing: how many flows do you need?

Authors:

Jan Budczies Michael Bockmayr Denise Treue Frederick Klauschen Carsten Denkert

Bioinformatics 2015 Apr 4;31(8):1199-203. Epub 2014 Dec 4.

Institute of Pathology, Charité University Hospital, Charitéplatz 1, 10117 Berlin, Germany, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany and German Consortium for Translational Cancer Research (DKTK), Berlin partner site, Charitéplatz 1, 10117 Berlin, Germany Institute of Pathology, Charité University Hospital, Charitéplatz 1, 10117 Berlin, Germany, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany and German Consortium for Translational Cancer Research (DKTK), Berlin partner site, Charitéplatz 1, 10117 Berlin, Germany.

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April 2015