Publications by authors named "Denis Headon"

42Publications

Characterisation of a second gain of function EDAR variant, encoding EDAR380R, in East Asia.

Eur J Hum Genet 2020 Jun 4. Epub 2020 Jun 4.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1038/s41431-020-0660-6DOI Listing
June 2020

Role of ectodysplasin signalling in middle ear and nasal pathology in rat and mouse models of hypohidrotic ectodermal dysplasia.

Dis Model Mech 2019 04 25;12(4). Epub 2019 Apr 25.

Developmental Biology Division, Roslin Institute and The Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh EH25 9RG, UK

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http://dx.doi.org/10.1242/dmm.037804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505480PMC
April 2019

A chemotaxis model of feather primordia pattern formation during avian development.

J Theor Biol 2018 01 31;437:225-238. Epub 2017 Oct 31.

Roslin Institute & Royal (Dick) School of Veterinary Studies, University of Edinburgh, UK.

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http://dx.doi.org/10.1016/j.jtbi.2017.10.026DOI Listing
January 2018

Hierarchical patterning modes orchestrate hair follicle morphogenesis.

PLoS Biol 2017 Jul 11;15(7):e2002117. Epub 2017 Jul 11.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.2002117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5507405PMC
July 2017

Reversing stratification during wound healing.

Authors:
Denis Headon

Nat Cell Biol 2017 May;19(6):595-597

Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, EH25 9RG, UK.

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http://dx.doi.org/10.1038/ncb3545DOI Listing
May 2017

Derivation of marker gene signatures from human skin and their use in the interpretation of the transcriptional changes associated with dermatological disorders.

J Pathol 2017 04 24;241(5):600-613. Epub 2017 Feb 24.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Midlothian, Edinburgh, EH25 9RG, UK.

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http://doi.wiley.com/10.1002/path.4864
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http://dx.doi.org/10.1002/path.4864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363360PMC
April 2017

FGF and EDA pathways control initiation and branching of distinct subsets of developing nasal glands.

Dev Biol 2016 11 30;419(2):348-356. Epub 2016 Aug 30.

Department of Craniofacial Development and Stem Cell Biology, Guy's Hospital, King's College London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2016.08.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145808PMC
November 2016

EGFR: stopping stathmin to start the cycle.

Authors:
Denis Headon

Exp Dermatol 2016 08 1;25(8):594-5. Epub 2016 Jun 1.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/exd.13019DOI Listing
August 2016

Hair Follicle Bulge Stem Cells Appear Dispensable for the Acute Phase of Wound Re-epithelialization.

Stem Cells 2016 05 2;34(5):1377-85. Epub 2016 Feb 2.

The Healing Foundation Centre, Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.

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http://dx.doi.org/10.1002/stem.2289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4985639PMC
May 2016

Maintenance of distinct melanocyte populations in the interfollicular epidermis.

Pigment Cell Melanoma Res 2015 Jul 30;28(4):476-80. Epub 2015 Apr 30.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, UK.

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http://dx.doi.org/10.1111/pcmr.12375DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973853PMC
July 2015

Morphological mutations: lessons from the cockscomb.

Authors:
Denis Headon

PLoS Genet 2015 Mar 19;11(3):e1004979. Epub 2015 Mar 19.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Roslin, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1004979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366248PMC
March 2015

Pharmacological stimulation of Edar signaling in the adult enhances sebaceous gland size and function.

J Invest Dermatol 2015 Feb 10;135(2):359-368. Epub 2014 Sep 10.

Department of Biochemistry, University of Lausanne, Epalinges, Switzerland. Electronic address:

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http://dx.doi.org/10.1038/jid.2014.382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269545PMC
February 2015

Regionalisation of the skin.

Semin Cell Dev Biol 2014 Jan-Feb;25-26:3-10. Epub 2013 Dec 18.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, EH25 9RG, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2013.12.007DOI Listing
January 2015

Cells or signals: which moves to drive skin pattern formation?

Authors:
Denis Headon

Exp Dermatol 2013 Dec;22(12):795-6

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, EH25 9RG, UK.

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http://dx.doi.org/10.1111/exd.12270DOI Listing
December 2013

The interfollicular epidermis of adult mouse tail comprises two distinct cell lineages that are differentially regulated by Wnt, Edaradd, and Lrig1.

Stem Cell Reports 2013 4;1(1):19-27. Epub 2013 Jun 4.

Centre for Stem Cells and Regenerative Medicine, King's College London, 28th Floor, Tower Wing, Guy's Hospital, Great Maze Pond, London SE1 9RT, UK.

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http://dx.doi.org/10.1016/j.stemcr.2013.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3757744PMC
May 2015

Roles of dental development and adaptation in rodent evolution.

Nat Commun 2013 ;4:2504

Team 'Evo-Devo of Vertebrate Dentition', Institut de Génomique Fonctionnelle de Lyon, ENS de Lyon, Université de Lyon, Université Lyon 1, CNRS, Ecole Normale Supérieure de Lyon, 32-34 avenue Tony Garnier, F-69007 Lyon, France.

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http://dx.doi.org/10.1038/ncomms3504DOI Listing
April 2014

Genome-wide SNP scan of pooled DNA reveals nonsense mutation in FGF20 in the scaleless line of featherless chickens.

BMC Genomics 2012 Jun 19;13:257. Epub 2012 Jun 19.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Midlothian, EH25 9RG, United Kingdom.

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http://dx.doi.org/10.1186/1471-2164-13-257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464622PMC
June 2012

The cell cycle regulator protein 14-3-3σ is essential for hair follicle integrity and epidermal homeostasis.

J Invest Dermatol 2012 Jun 1;132(6):1543-53. Epub 2012 Mar 1.

Faculty of Medical and Human Science and Faculty of Life Sciences, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1038/jid.2012.27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378636PMC
June 2012

The influence of receptor-mediated interactions on reaction-diffusion mechanisms of cellular self-organisation.

Bull Math Biol 2012 Apr 10;74(4):935-57. Epub 2011 Nov 10.

Department of Mathematics, FNSPE, Czech Technical University in Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1007/s11538-011-9699-4DOI Listing
April 2012

Cryptic patterning of avian skin confers a developmental facility for loss of neck feathering.

PLoS Biol 2011 Mar 15;9(3):e1001028. Epub 2011 Mar 15.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom.

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http://dx.doi.org/10.1371/journal.pbio.1001028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057954PMC
March 2011

Creation of arrays of cell aggregates in defined patterns for developmental biology studies using dielectrophoresis.

Biotechnol Bioeng 2010 Apr;105(5):945-54

Microstructures and Microenvironments Research Group, Department of Chemical Engineering, School of Engineering and Physical Sciences, Heriot-Watt University, Riccarton, Edinburgh EH14 4AS, Scotland, UK.

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http://dx.doi.org/10.1002/bit.22615DOI Listing
April 2010

Enhanced Edar signalling has pleiotropic effects on craniofacial and cutaneous glands.

PLoS One 2009 Oct 26;4(10):e7591. Epub 2009 Oct 26.

Faculty of Life Sciences, University of Manchester, Manchester, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007591PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2762540PMC
October 2009

Hair follicles are required for optimal growth during lateral skin expansion.

J Invest Dermatol 2009 Oct 23;129(10):2358-64. Epub 2009 Apr 23.

Faculty of Life Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1038/jid.2009.102DOI Listing
October 2009

Distinct impacts of Eda and Edar loss of function on the mouse dentition.

PLoS One 2009 2;4(4):e4985. Epub 2009 Apr 2.

Institut International de Paléoprimatologie Paléontologie Humaine, Evolution et Paléoenvironnements UMR CNRS 6046, Université de Poitiers, Poitiers, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004985PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659790PMC
July 2009

Ectodysplasin signaling in cutaneous appendage development: dose, duration, and diversity.

Authors:
Denis J Headon

J Invest Dermatol 2009 Apr;129(4):817-9

Division of Developmental Biology, Roslin Institute and R(D)SVS, University of Edinburgh, Midlothian, United Kingdom.

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http://dx.doi.org/10.1038/jid.2008.426DOI Listing
April 2009

An extended epidermal response heals cutaneous wounds in the absence of a hair follicle stem cell contribution.

J Invest Dermatol 2008 May 22;128(5):1311-8. Epub 2007 Nov 22.

Faculty of Life Sciences, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1038/sj.jid.5701178DOI Listing
May 2008

The Edar subfamily in feather placode formation.

Dev Biol 2007 May 16;305(1):232-45. Epub 2007 Feb 16.

Faculty of Life Sciences, University of Manchester, Oxford Road, Manchester, M13 9PT, UK.

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http://dx.doi.org/10.1016/j.ydbio.2007.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696204PMC
May 2007

Generation of the primary hair follicle pattern.

Proc Natl Acad Sci U S A 2006 Jun 12;103(24):9075-80. Epub 2006 Jun 12.

Faculty of Life Sciences, University of Manchester, Manchester M13 9PT, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0600825103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1482568PMC
June 2006

A germline variation in the progesterone receptor gene increases transcriptional activity and may modify ovarian cancer risk.

J Clin Endocrinol Metab 2004 Dec;89(12):6340-7

Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1210/jc.2004-0114DOI Listing
December 2004