Denis Furling

Denis Furling

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Denis Furling

Denis Furling

Publications by authors named "Denis Furling"

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FISH Protocol for Myotonic Dystrophy Type 1 Cells.

Methods Mol Biol 2020 ;2056:203-215

Centre de Recherche en Myologie, Sorbonne Univeristé, Paris, France.

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http://dx.doi.org/10.1007/978-1-4939-9784-8_13DOI Listing
January 2020

miR-7 Restores Phenotypes in Myotonic Dystrophy Muscle Cells by Repressing Hyperactivated Autophagy.

Mol Ther Nucleic Acids 2019 Nov 20;19:278-292. Epub 2019 Nov 20.

Translational Genomics Group, Incliva Health Research Institute, Valencia 46100, Spain; Interdisciplinary Research Structure for Biotechnology and Biomedicine (ERI BIOTECMED), University of Valencia, Valencia 46100, Spain; CIPF-INCLIVA Joint Unit, Valencia 46012, Spain.

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http://dx.doi.org/10.1016/j.omtn.2019.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6926285PMC
November 2019

Cardiovascular manifestations of myotonic dystrophy.

Trends Cardiovasc Med 2019 Jun 13. Epub 2019 Jun 13.

Sorbonne Université, INSERM, Association Institut de Myologie, Centre de Recherche en Myologie, Paris, France.

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http://dx.doi.org/10.1016/j.tcm.2019.06.001DOI Listing
June 2019

Improvement of Dystrophic Muscle Fragility by Short-Term Voluntary Exercise through Activation of Calcineurin Pathway in mdx Mice.

Am J Pathol 2018 11 22;188(11):2662-2673. Epub 2018 Aug 22.

Research Center in Myology, Association Institute of Myology, Sorbonne University, INSERM, UMRS974, Paris, France; Paris Descartes University, Sorbonne Paris Cité, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029440183002
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http://dx.doi.org/10.1016/j.ajpath.2018.07.015DOI Listing
November 2018

High Risk of Fatal and Nonfatal Venous Thromboembolism in Myotonic Dystrophy.

Circulation 2018 09;138(11):1169-1171

Assistance Publique des Hôpitaux de Paris, Cochin Hospital, Cardiology Department, Centre de Référence de Pathologie Neuromusculaire Nord/Est/Ile de France, Paris-Descartes, Sorbonne Paris Cité University, France (M.S., D.D., K.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.035035DOI Listing
September 2018

Cells of Matter- Models for Myotonic Dystrophy.

Front Neurol 2018 23;9:361. Epub 2018 May 23.

Sorbonne Université, INSERM, Association Institut de Myologie, Centre de Recherche en Myologie, Paris, France.

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http://dx.doi.org/10.3389/fneur.2018.00361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5974047PMC
May 2018

Effect of constitutive inactivation of the myostatin gene on the gain in muscle strength during postnatal growth in two murine models.

Muscle Nerve 2017 02 12;55(2):254-261. Epub 2016 Nov 12.

Sorbonne Universités CNRS, Centre de Recherche en Myologie, Paris, France.

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http://doi.wiley.com/10.1002/mus.25220
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http://dx.doi.org/10.1002/mus.25220DOI Listing
February 2017

Precise small-molecule recognition of a toxic CUG RNA repeat expansion.

Nat Chem Biol 2017 02 12;13(2):188-193. Epub 2016 Dec 12.

Departments of Chemistry and Neuroscience, The Scripps Research Institute, Jupiter, Florida, USA.

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http://dx.doi.org/10.1038/nchembio.2251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5290590PMC
February 2017

CRISPR/Cas9-Induced (CTG⋅CAG) Repeat Instability in the Myotonic Dystrophy Type 1 Locus: Implications for Therapeutic Genome Editing.

Mol Ther 2017 01 4;25(1):24-43. Epub 2017 Jan 4.

Radboud Institute for Molecular Life Sciences, Department of Cell Biology, Radboud University Medical Center, Geert Grooteplein 28, 6525 GA, Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2016.10.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363205PMC
January 2017

Dystrophin restoration therapy improves both the reduced excitability and the force drop induced by lengthening contractions in dystrophic mdx skeletal muscle.

Skelet Muscle 2016 20;6:23. Epub 2016 Jul 20.

Groupe Hospitalier Pitié Salpêtrière, Centre de Recherche en Myologie, CNRS, Inserm, UPMC Univ Paris 06, Sorbonne Universités, Paris, F-75013 France ; Sorbonne Paris Cité, Université Paris Descartes, Paris, F-75006 France ; Groupe Hospitalier Pitié-Salpétrière, Institut de Myologie, F-75013 Paris, France.

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http://skeletalmusclejournal.biomedcentral.com/articles/10.1
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http://dx.doi.org/10.1186/s13395-016-0096-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4952281PMC
October 2016

Lentiviral vector-mediated overexpression of mutant ataxin-7 recapitulates SCA7 pathology and promotes accumulation of the FUS/TLS and MBNL1 RNA-binding proteins.

Mol Neurodegener 2016 07 28;11(1):58. Epub 2016 Jul 28.

INSERM U 1127, CNRS UMR 7225, Sorbonne Universités UPMC, Univ Paris 06 UMR_S 1127, ICM (Brain and Spine Institute) Pitié-Salpêtrière Hospital, 75013, Paris, France.

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http://dx.doi.org/10.1186/s13024-016-0123-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964261PMC
July 2016

RBFOX1 cooperates with MBNL1 to control splicing in muscle, including events altered in myotonic dystrophy type 1.

PLoS One 2014 11;9(9):e107324. Epub 2014 Sep 11.

Department of Microbiology and Infectiology, Faculty of Medicine and Heath Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada; Laboratory of Functional Genomics, Faculty of Medicine and Heath Sciences, Université de Sherbrooke, Sherbrooke, Quebec, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107324PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161394PMC
October 2015

MyoD transcription factor induces myogenesis by inhibiting Twist-1 through miR-206.

J Cell Sci 2015 Oct 13;128(19):3631-45. Epub 2015 Aug 13.

Department of Molecular Genetics, Function & Therapy, Cyprus Institute of Neurology and Genetics, Nicosia,1683, Cyprus

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http://dx.doi.org/10.1242/jcs.172288DOI Listing
October 2015

Mechanical Overloading Increases Maximal Force and Reduces Fragility in Hind Limb Skeletal Muscle from Mdx Mouse.

Am J Pathol 2015 Jul 23;185(7):2012-24. Epub 2015 May 23.

Biological Adaptation and Aging, Institut de Biologie Paris-Seine, Centre National de la Recherche Scientifique UMR 8256, Université Pierre et Marie Curie-Paris 6, Sorbonne Universités, Paris, France.

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http://dx.doi.org/10.1016/j.ajpath.2015.03.027DOI Listing
July 2015

Nuclear protein spreading: implication for pathophysiology of neuromuscular diseases.

Hum Mol Genet 2014 Aug 21;23(15):4125-33. Epub 2014 Mar 21.

Sorbonne Universités, UPMC Univ Paris 06, Myology Research Center UM76, F-75013 Paris, France, INSERM UMRS974, F-75013 Paris, France, CNRS FRE 3617, F-75013 Paris, France and Institut de Myologie, F-75013 Paris, France

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http://dx.doi.org/10.1093/hmg/ddu129DOI Listing
August 2014

[Misregulation of alternative splicing and microRNA processing in DM1 pathogenesis].

Authors:
Denis Furling

Rinsho Shinkeigaku 2012 ;52(11):1018-22

UPMC Univ Paris 06, UM 76, Institut de Myologie, Paris, France.

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http://dx.doi.org/10.5692/clinicalneurol.52.1018DOI Listing
April 2014

In-depth analysis of the secretome identifies three major independent secretory pathways in differentiating human myoblasts.

J Proteomics 2012 Dec 20;77:344-56. Epub 2012 Sep 20.

Université Pierre et Marie Curie, Paris 6, UM76, Institut de Myologie, Bâtiment Babinski, GH Pitié Salpêtrière, 47, bd de l'Hôpital, Paris, F-75013, France.

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http://dx.doi.org/10.1016/j.jprot.2012.09.008DOI Listing
December 2012

New function for the RNA helicase p68/DDX5 as a modifier of MBNL1 activity on expanded CUG repeats.

Nucleic Acids Res 2012 Apr 9;40(7):3159-71. Epub 2011 Dec 9.

Centre de Génétique Moléculaire, CNRS, UPR 3404, Avenue de Terrasse, 91198 Gif-sur-Yvette, Université Paris-Sud, Orsay, France.

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http://nar.oxfordjournals.org/content/early/2011/12/09/nar.g
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gkr1228
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http://dx.doi.org/10.1093/nar/gkr1228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326330PMC
April 2012

Abnormal prostaglandin E2 production blocks myogenic differentiation in myotonic dystrophy.

Neurobiol Dis 2012 Jan 25;45(1):122-9. Epub 2011 Jun 25.

Neuroscience Research Unit, Laval University, CHUQ, Pavillon CHUL, Ste-Foy, Quebec, Canada G1V 4G2.

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http://dx.doi.org/10.1016/j.nbd.2011.06.014DOI Listing
January 2012

Endogenous TWIST expression and differentiation are opposite during human muscle development.

Muscle Nerve 2011 Dec;44(6):984-6

Department of Molecular Genetics, Function & Therapy, Cyprus Institute of Neurology and Genetics, Nicosia, Cyprus.

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http://dx.doi.org/10.1002/mus.22241DOI Listing
December 2011

Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle.

BMC Dev Biol 2011 Jun 7;11:34. Epub 2011 Jun 7.

Department of Molecular Genetics, Function & Therapy, The Cyprus Institute of Neurology & Genetics, PO Box 2346, 1683 Nicosia, Cyprus.

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http://dx.doi.org/10.1186/1471-213X-11-34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3132729PMC
June 2011

Steroid receptor RNA activator protein binds to and counteracts SRA RNA-mediated activation of MyoD and muscle differentiation.

Nucleic Acids Res 2011 Jan 19;39(2):513-25. Epub 2010 Sep 19.

Université Paris Diderot-Paris7, CNRS UMR7216, Epigenetics and Cell Fate, Paris, France.

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http://dx.doi.org/10.1093/nar/gkq833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025577PMC
January 2011

Selective silencing of mutated mRNAs in DM1 by using modified hU7-snRNAs.

Nat Struct Mol Biol 2011 Jan 26;18(1):85-7. Epub 2010 Dec 26.

Université Pierre et Marie Curie-Paris6, Um76, Paris, France.

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http://dx.doi.org/10.1038/nsmb.1958DOI Listing
January 2011

Triplet-repeat oligonucleotide-mediated reversal of RNA toxicity in myotonic dystrophy.

Proc Natl Acad Sci U S A 2009 Aug 10;106(33):13915-20. Epub 2009 Aug 10.

Department of Cell Biology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1073/pnas.0905780106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728995PMC
August 2009

A cell-based bicistronic lentiviral reporter system for identification of inhibitors of the hepatitis C virus internal ribosome entry site.

J Virol Methods 2009 Jun 14;158(1-2):152-9. Epub 2009 Feb 14.

Laboratoire de Virologie, CERVI, Unité Propre de Recherche et d'Enseignement Supérieur de l'UPMC, Université Paris 6 EA 2387, IFR 113, Groupe Hospitalier Pitié-Salpêtrière, Paris Cedex 13, France.

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http://dx.doi.org/10.1016/j.jviromet.2009.02.007DOI Listing
June 2009

Muscleblind-like proteins: similarities and differences in normal and myotonic dystrophy muscle.

Am J Pathol 2009 Jan 18;174(1):216-27. Epub 2008 Dec 18.

Wolfson Centre for Inherited Neuromuscular Disease, RJAH Orthopaedic Hospital, Oswestry, Shropshire, United Kingdom.

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http://linkinghub.elsevier.com/retrieve/pii/S000294401061280
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http://dx.doi.org/10.2353/ajpath.2009.080520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631334PMC
January 2009

Replicative aging down-regulates the myogenic regulatory factors in human myoblasts.

Biol Cell 2008 Mar;100(3):189-99

Inserm, Université Pierre and Marie Curie-Paris 6, UMR S 787, Institut de Myologie, Paris 75013, France.

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http://dx.doi.org/10.1042/BC20070085DOI Listing
March 2008

Defective mRNA in myotonic dystrophy accumulates at the periphery of nuclear splicing speckles.

Genes Cells 2007 Sep;12(9):1035-48

Wolfson Centre for Inherited Neuromuscular Disease, Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, SY10 7AG, UK.

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http://dx.doi.org/10.1111/j.1365-2443.2007.01112.xDOI Listing
September 2007

IL-13 mediates the recruitment of reserve cells for fusion during IGF-1-induced hypertrophy of human myotubes.

J Cell Sci 2007 Feb 30;120(Pt 4):670-81. Epub 2007 Jan 30.

UMR S 787, Inserm/UPMC-Paris 6, Institut de Myologie, Paris, France.

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http://jcs.biologists.org/cgi/doi/10.1242/jcs.03371
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http://dx.doi.org/10.1242/jcs.03371DOI Listing
February 2007

Myocytes from congenital myotonic dystrophy display abnormal Na+ channel activities.

Muscle Nerve 2005 Apr;31(4):506-9

Department of Physiology and Pathology, University of Trieste, Via Fleming 22, 34127 Trieste, Italy.

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http://dx.doi.org/10.1002/mus.20235DOI Listing
April 2005

Changes in myotonic dystrophy protein kinase levels and muscle development in congenital myotonic dystrophy.

Am J Pathol 2003 Mar;162(3):1001-9

Centre National de la Recherche Scientifique Unité Mixte de Recherche 7000, Faculté de Médecine Pitié-Salpêtrière, Paris, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868110PMC
http://dx.doi.org/10.1016/s0002-9440(10)63894-1DOI Listing
March 2003

Muscle-specific alternative splicing of myotubularin-related 1 gene is impaired in DM1 muscle cells.

Hum Mol Genet 2002 Sep;11(19):2297-307

Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS/INSERM/ULP, 1 rue Laurent Fries, BP 163, 67404 Illkirch Cedex, CU de Strasbourg, France.

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http://dx.doi.org/10.1093/hmg/11.19.2297DOI Listing
September 2002