Publications by authors named "Deming Zhao"

100Publications

Retraction Note to: Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.

Neurotherapeutics 2020 Aug 10. Epub 2020 Aug 10.

National Animal Transmissible Spongiform Encephalopathy Laboratory and Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, 100193, China.

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http://dx.doi.org/10.1007/s13311-020-00909-3DOI Listing
August 2020

Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases.

Aging (Albany NY) 2020 06 10;12(11):11139-11151. Epub 2020 Jun 10.

Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

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http://dx.doi.org/10.18632/aging.103328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7346071PMC
June 2020

Corrigendum: The Role of the Gut Microbiota in the Pathogenesis of Parkinson's Disease.

Front Neurol 2019;10:1412. Epub 2020 Feb 6.

Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.3389/fneur.2019.01412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017782PMC
February 2020

Complementary Oxidative Generation of Iminyl Radicals from α-Imino-oxy Acids: Silver-Catalyzed C-H Cyanoalkylation of Heterocycles and Quinones.

J Org Chem 2020 Feb 21;85(4):2504-2511. Epub 2020 Jan 21.

College of Chemical Engineering , Zhejiang University of Technology , Hangzhou 310014 , P. R. China.

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http://dx.doi.org/10.1021/acs.joc.9b03204DOI Listing
February 2020

Implications of gut microbiota dysbiosis and metabolic changes in prion disease.

Neurobiol Dis 2020 02 16;135:104704. Epub 2019 Dec 16.

Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.104704DOI Listing
February 2020

Inhibition of type I interferon signaling abrogates early Mycobacterium bovis infection.

BMC Infect Dis 2019 Dec 4;19(1):1031. Epub 2019 Dec 4.

Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.1186/s12879-019-4654-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894119PMC
December 2019

PP2Ac Modulates AMPK-Mediated Induction of Autophagy in -Infected Macrophages.

Int J Mol Sci 2019 Nov 29;20(23). Epub 2019 Nov 29.

Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

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http://dx.doi.org/10.3390/ijms20236030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6928646PMC
November 2019

The Role of the Gut Microbiota in the Pathogenesis of Parkinson's Disease.

Front Neurol 2019 6;10:1155. Epub 2019 Nov 6.

Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.3389/fneur.2019.01155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851172PMC
November 2019

OPA1 overexpression ameliorates mitochondrial cristae remodeling, mitochondrial dysfunction, and neuronal apoptosis in prion diseases.

Cell Death Dis 2019 09 24;10(10):710. Epub 2019 Sep 24.

Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.1038/s41419-019-1953-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6760175PMC
September 2019

Mitochondrial Transcription Factor A Regulates Mycobacterium bovis-Induced IFN-β Production by Modulating Mitochondrial DNA Replication in Macrophages.

J Infect Dis 2020 01;221(3):438-448

Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.1093/infdis/jiz461DOI Listing
January 2020

Detection of Cell-Free Mitochondrial DNA in Cerebrospinal Fluid of Creutzfeldt-Jakob Patients.

Front Neurol 2019 21;10:645. Epub 2019 Jun 21.

Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.3389/fneur.2019.00645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598448PMC
June 2019

Matrix metalloproteinases: Expression, regulation and role in the immunopathology of tuberculosis.

Cell Prolif 2019 Jul 14;52(4):e12649. Epub 2019 Jun 14.

Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.1111/cpr.12649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668971PMC
July 2019

Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy.

Cells 2019 05 26;8(5). Epub 2019 May 26.

Key Laboratory of Animal Epidemiology and Zoonosis of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

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http://dx.doi.org/10.3390/cells8050506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562972PMC
May 2019

Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Infection by Modulating Autophagy and Apoptosis.

Cells 2019 05 5;8(5). Epub 2019 May 5.

Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

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http://dx.doi.org/10.3390/cells8050415DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562459PMC
May 2019

Endoplasmic Reticulum Stress Induces Macrophages to Produce IL-1β During Infection via a Positive Feedback Loop Between Mitochondrial Damage and Inflammasome Activation.

Front Immunol 2019 21;10:268. Epub 2019 Feb 21.

Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.3389/fimmu.2019.00268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394253PMC
July 2020

Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.

Int J Mol Sci 2019 Mar 6;20(5). Epub 2019 Mar 6.

State Key Laboratory for Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

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http://dx.doi.org/10.3390/ijms20051144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429086PMC
March 2019

cGAS/STING/TBK1/IRF3 Signaling Pathway Activates BMDCs Maturation Following Infection.

Int J Mol Sci 2019 Feb 19;20(4). Epub 2019 Feb 19.

College of Agriculture, Ningxia University, Xixia District, Yinchuan 750021, China.

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http://dx.doi.org/10.3390/ijms20040895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412216PMC
February 2019

Comparative Study of the Molecular Basis of Pathogenicity of Strains in a Mouse Model.

Int J Mol Sci 2018 Dec 20;20(1). Epub 2018 Dec 20.

State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

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http://www.mdpi.com/1422-0067/20/1/5
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http://dx.doi.org/10.3390/ijms20010005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337294PMC
December 2018

p62-Keap1-NRF2-ARE Pathway: A Contentious Player for Selective Targeting of Autophagy, Oxidative Stress and Mitochondrial Dysfunction in Prion Diseases.

Front Mol Neurosci 2018 4;11:310. Epub 2018 Oct 4.

National Animal Transmissible Spongiform Encephalopathy Laboratory, Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, China.

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https://www.frontiersin.org/article/10.3389/fnmol.2018.00310
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http://dx.doi.org/10.3389/fnmol.2018.00310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180192PMC
October 2018

MicroRNA-199a Inhibits Cellular Autophagy and Downregulates IFN-β Expression by Targeting TBK1 in Infected Cells.

Front Cell Infect Microbiol 2018 10;8:238. Epub 2018 Jul 10.

State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.3389/fcimb.2018.00238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048223PMC
August 2019

Regulation of MicroRNAs-Mediated Autophagic Flux: A New Regulatory Avenue for Neurodegenerative Diseases With Focus on Prion Diseases.

Front Aging Neurosci 2018 15;10:139. Epub 2018 May 15.

National Animal Transmissible Spongiform Encephalopathy Laboratory and Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.3389/fnagi.2018.00139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962651PMC
May 2018

Prion protein is essential for the RE1 silencing transcription factor (REST)-dependent developmental switch in synaptic NMDA receptors.

Cell Death Dis 2018 05 1;9(5):541. Epub 2018 May 1.

The State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, 100193, Beijing, China.

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http://dx.doi.org/10.1038/s41419-018-0576-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5945644PMC
May 2018

The NLRP3-Caspase 1 Inflammasome Negatively Regulates Autophagy via TLR4-TRIF in Prion Peptide-Infected Microglia.

Front Aging Neurosci 2018 18;10:116. Epub 2018 Apr 18.

National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.3389/fnagi.2018.00116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915529PMC
April 2018

miRNAs in Tuberculosis: New Avenues for Diagnosis and Host-Directed Therapy.

Front Microbiol 2018 29;9:602. Epub 2018 Mar 29.

State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://journal.frontiersin.org/article/10.3389/fmicb.2018.00
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http://dx.doi.org/10.3389/fmicb.2018.00602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885483PMC
March 2018

MicroRNA 27a-3p Regulates Antimicrobial Responses of Murine Macrophages Infected by subspecies by Targeting Interleukin-10 and TGF-β-Activated Protein Kinase 1 Binding Protein 2.

Front Immunol 2017 11;8:1915. Epub 2018 Jan 11.

State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.3389/fimmu.2017.01915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5768609PMC
January 2018

IFN-β: A Contentious Player in Host-Pathogen Interaction in Tuberculosis.

Int J Mol Sci 2017 Dec 16;18(12). Epub 2017 Dec 16.

State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology of the Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

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http://dx.doi.org/10.3390/ijms18122725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751326PMC
December 2017

DLP1-dependent mitochondrial fragmentation and redistribution mediate prion-associated mitochondrial dysfunction and neuronal death.

Aging Cell 2018 02 22;17(1). Epub 2017 Nov 22.

National Animal Transmissible Spongiform Encephalopathy Laboratory, State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology and Zoonosis, College of Veterinary Medicine, Ministry of Agriculture, China Agricultural University, Beijing, 100193, China.

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http://dx.doi.org/10.1111/acel.12693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771399PMC
February 2018

A novel G-quadruplex motif in the Human promoter region.

Biosci Rep 2017 Dec 29;37(6). Epub 2017 Nov 29.

Department of Biochemistry and Molecular Biology, China Medical University, Shenyang, Liaoning 110122, China.

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http://dx.doi.org/10.1042/BSR20171128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705779PMC
December 2017

Role of the AMPK pathway in promoting autophagic flux via modulating mitochondrial dynamics in neurodegenerative diseases: Insight into prion diseases.

Ageing Res Rev 2017 Nov 10;40:51-63. Epub 2017 Sep 10.

National Animal Transmissible Spongiform Encephalopathy Laboratory and Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing 100193, China. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2017.09.004DOI Listing
November 2017

Differences in pathogenicity of three animal isolates of Mycobacterium species in a mouse model.

PLoS One 2017 24;12(8):e0183666. Epub 2017 Aug 24.

State Key Laboratory of Agrobiotechnology, Key Laboratory of Animal Epidemiology of the Ministry of Agriculture and College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183666PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570376PMC
October 2017

Lithium alleviates neurotoxic prion peptide-induced synaptic damage and neuronal death partially by the upregulation of nuclear target REST and the restoration of Wnt signaling.

Neuropharmacology 2017 Sep 22;123:332-348. Epub 2017 May 22.

The State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2017.05.021DOI Listing
September 2017

The Central Role of IFI204 in IFN-β Release and Autophagy Activation during Infection.

Front Cell Infect Microbiol 2017 5;7:169. Epub 2017 May 5.

State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural UniversityBeijing, China.

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http://dx.doi.org/10.3389/fcimb.2017.00169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418236PMC
December 2017

Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-β-Catenin Signaling in Prion Diseases Models.

Front Mol Neurosci 2017 3;10:128. Epub 2017 May 3.

The State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural UniversityBeijing, China.

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http://journal.frontiersin.org/article/10.3389/fnmol.2017.00
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http://dx.doi.org/10.3389/fnmol.2017.00128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413570PMC
May 2017

The Role of Unfolded Protein Response and Mitogen-Activated Protein Kinase Signaling in Neurodegenerative Diseases with Special Focus on Prion Diseases.

Front Aging Neurosci 2017 1;9:120. Epub 2017 May 1.

National Animal Transmissible Spongiform Encephalopathy Laboratory and Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural UniversityBeijing, China.

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http://dx.doi.org/10.3389/fnagi.2017.00120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5410568PMC
May 2017

Fatal bacterial septicemia in a bottlenose dolphin Tursiops truncatus caused by Streptococcus iniae.

Dis Aquat Organ 2017 01;122(3):195-203

The State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture; National Animal Transmissible Spongiform Encephalopathy Laboratory; Department of Veterinary Pathology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, PR China.

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http://dx.doi.org/10.3354/dao03069DOI Listing
January 2017

Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters.

Neurotherapeutics 2017 04;14(2):463-483

National Animal Transmissible Spongiform Encephalopathy Laboratory and Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, 100193, China.

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http://dx.doi.org/10.1007/s13311-016-0500-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398981PMC
April 2017

Induces Endoplasmic Reticulum Stress Mediated-Apoptosis by Activating IRF3 in a Murine Macrophage Cell Line.

Front Cell Infect Microbiol 2016 12;6:182. Epub 2016 Dec 12.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University Beijing, China.

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http://journal.frontiersin.org/article/10.3389/fcimb.2016.00
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http://dx.doi.org/10.3389/fcimb.2016.00182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149527PMC
September 2017

The role of IL-10 in Mycobacterium avium subsp. paratuberculosis infection.

Cell Commun Signal 2016 12 1;14(1):29. Epub 2016 Dec 1.

National Animal Transmissible Spongiform Encephalopathy Laboratory and key Laboratory of Animal and Zoonosis of Ministry Agriculture, College of Veterinary Medicine and State key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, 100193, People's Republic of China.

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http://dx.doi.org/10.1186/s12964-016-0152-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5131435PMC
December 2016

Defensins: The Case for Their Use against Mycobacterial Infections.

J Immunol Res 2016 20;2016:7515687. Epub 2016 Sep 20.

National Animal Transmissible Spongiform Encephalopathy Laboratory, Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine and State Key Lab of Agrobiotechnology, China Agricultural University, Beijing, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5048032PMC
http://dx.doi.org/10.1155/2016/7515687DOI Listing
March 2017

A central role for calcineurin in protein misfolding neurodegenerative diseases.

Cell Mol Life Sci 2017 03 28;74(6):1061-1074. Epub 2016 Sep 28.

National Animal Transmissible Spongiform Encephalopathy Laboratory and Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, 100193, China.

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http://dx.doi.org/10.1007/s00018-016-2379-7DOI Listing
March 2017

Proteome Analysis of Potential Synaptic Vesicle Cycle Biomarkers in the Cerebrospinal Fluid of Patients with Sporadic Creutzfeldt-Jakob Disease.

Mol Neurobiol 2017 09 25;54(7):5177-5191. Epub 2016 Aug 25.

National Animal Transmissible Spongiform Encephalopathy Laboratory, Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, 100193, China.

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http://dx.doi.org/10.1007/s12035-016-0029-6DOI Listing
September 2017

Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells.

Cell Mol Neurobiol 2017 May 18;37(4):717-728. Epub 2016 Jul 18.

National Animal Transmissible Spongiform Encephalopathy Laboratory, Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing, China.

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http://dx.doi.org/10.1007/s10571-016-0407-7DOI Listing
May 2017

AIM2 inhibits autophagy and IFN-β production during M. bovis infection.

Oncotarget 2016 Jul;7(30):46972-46987

State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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http://www.oncotarget.com/fulltext/10503
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http://dx.doi.org/10.18632/oncotarget.10503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216917PMC
July 2016

Polymorphism analysis of prion protein gene in 11 Pakistani goat breeds.

Prion 2016 07;10(4):290-304

a Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University , Beijing , China.

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http://dx.doi.org/10.1080/19336896.2016.1178422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082961PMC
July 2016

Erratum to: Cellular Prion Protein Promotes Neuronal Differentiation of Adipose-Derived Stem Cells by Upregulating miRNA-124.

J Mol Neurosci 2016 05;59(1):56-57

Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China.

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http://dx.doi.org/10.1007/s12031-016-0752-5DOI Listing
May 2016

Virulent Mycobacterium bovis Beijing Strain Activates the NLRP7 Inflammasome in THP-1 Macrophages.

PLoS One 2016 4;11(4):e0152853. Epub 2016 Apr 4.

National Animal Transmissible Spongiform Encephalopathy Laboratory, Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University, Beijing 100193, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0152853PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820140PMC
August 2016

The isolation and molecular characterization of Mycobacterium avium subsp. paratuberculosis in Shandong province, China.

Gut Pathog 2016 22;8. Epub 2016 Mar 22.

State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193 China.

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http://dx.doi.org/10.1186/s13099-016-0092-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802609PMC
March 2016

The endoplasmic reticulum stress response: A link with tuberculosis?

Tuberculosis (Edinb) 2016 Mar 2;97:52-6. Epub 2016 Jan 2.

The State Key Lab of Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National TSE Lab, College of Veterinary Medicine, China Agricultural University, Beijing 100193, PR China. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2015.12.009DOI Listing
March 2016

Role of the Retromer Complex in Neurodegenerative Diseases.

Front Aging Neurosci 2016 1;8:42. Epub 2016 Mar 1.

National Animal Transmissible Spongiform Encephalopathy Laboratory, Key Laboratory of Animal Epidemiology and Zoonosis of Ministry of Agriculture, College of Veterinary Medicine and State Key Laboratory of Agrobiotechnology, China Agricultural University Beijing, China.

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http://dx.doi.org/10.3389/fnagi.2016.00042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772447PMC
March 2016

Cellular Prion Protein Promotes Neuronal Differentiation of Adipose-Derived Stem Cells by Upregulating miRNA-124.

J Mol Neurosci 2016 May 7;59(1):48-55. Epub 2016 Mar 7.

Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, 310058, China.

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http://dx.doi.org/10.1007/s12031-016-0733-8DOI Listing
May 2016

REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling.

Oncotarget 2016 Mar;7(11):12035-52

The State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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March 2016

HDAC6 alleviates prion peptide-mediated neuronal death via modulating PI3K-Akt-mTOR pathway.

Neurobiol Aging 2016 Jan 9;37:91-102. Epub 2015 Oct 9.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China. Electronic address:

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January 2016

Proteomic Analysis of Protein Expression Throughout Disease Progression in a Mouse Model of Alzheimer's Disease.

J Alzheimers Dis 2015 ;47(4):915-26

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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July 2016

Unfolded Protein Response Pathways in Neurodegenerative Diseases.

J Mol Neurosci 2015 Dec 25;57(4):529-37. Epub 2015 Aug 25.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

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December 2015

Downregulation of β-Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein: Proteomics-Based Identification in Early-Stage Prion Disease.

Neurodegener Dis 2015 22;15(4):193-201. Epub 2015 May 22.

State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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April 2016

Inflammasomes-dependent regulation of IL-1β secretion induced by the virulent Mycobacterium bovis Beijing strain in THP-1 macrophages.

Antonie Van Leeuwenhoek 2015 Jul 16;108(1):163-71. Epub 2015 May 16.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

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July 2015

Death Receptor 6 and Caspase-6 Regulate Prion Peptide-Induced Axonal Degeneration in Rat Spinal Neurons.

J Mol Neurosci 2015 Aug 22;56(4):966-976. Epub 2015 Apr 22.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

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August 2015

Amyloid-β Activates Microglia and Regulates Protein Expression in a Manner Similar to Prions.

J Mol Neurosci 2015 Jun 14;56(2):509-18. Epub 2015 Apr 14.

State Key Laboratories for Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, 100193, Beijing, China,

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June 2015

Regulatory Mechanisms of Endoplasmic Reticulum Resident IP3 Receptors.

J Mol Neurosci 2015 Aug 10;56(4):938-948. Epub 2015 Apr 10.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

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August 2015

Protein misfolding cyclic amplification induces the conversion of recombinant prion protein to PrP oligomers causing neuronal apoptosis.

J Neurochem 2015 Jun 13;133(5):722-9. Epub 2015 Apr 13.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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June 2015

Transcriptome changes upon in vitro challenge with Mycobacterium bovis in monocyte-derived macrophages from bovine tuberculosis-infected and healthy cows.

Vet Immunol Immunopathol 2015 Feb 11;163(3-4):146-56. Epub 2014 Dec 11.

The State Key Lab of Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National TSE Lab, College of Veterinary Medicine, China Agricultural University, 2 Yuanmingyuan West Road, Beijing 100193, China. Electronic address:

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February 2015

Comparative study of the growth and survival of recombinant Mycobacterium smegmatis expressing Mce4A and Mce4E from Mycobacterium bovis.

DNA Cell Biol 2015 Feb 23;34(2):125-32. Epub 2014 Dec 23.

1 The State Key Lab of Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis Ministry of Agriculture, National TSE Lab, College of Veterinary Medicine, China Agricultural University , Beijing, People's Republic of China .

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February 2015

NRSF: an angel or a devil in neurogenesis and neurological diseases.

J Mol Neurosci 2015 May 6;56(1):131-44. Epub 2014 Dec 6.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

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May 2015

Toll-like receptor 2 deficiency shifts PrP106-126-induced microglial activation from a neurotoxic to a neuroprotective phenotype.

J Mol Neurosci 2015 Apr 21;55(4):880-90. Epub 2014 Oct 21.

State Key Lab of Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, 100193, Beijing, People's Republic of China,

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April 2015

Metabolism of minor isoforms of prion proteins: Cytosolic prion protein and transmembrane prion protein.

Neural Regen Res 2013 Oct;8(30):2868-78

State Key Laboratory for Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4146015PMC
October 2013

The cellular prion protein negatively regulates phagocytosis and cytokine expression in murine bone marrow-derived macrophages.

PLoS One 2014 24;9(7):e102785. Epub 2014 Jul 24.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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April 2015

Protein-based biomarkers in cerebrospinal fluid and blood for Alzheimer's disease.

J Mol Neurosci 2014 Dec 25;54(4):739-47. Epub 2014 Jun 25.

State Key Laboratories for Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

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December 2014

Prion protein participates in the protection of mice from lipopolysaccharide infection by regulating the inflammatory process.

J Mol Neurosci 2015 Jan 20;55(1):279-287. Epub 2014 May 20.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

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January 2015

Regulation of proteasomes in prion disease.

Acta Biochim Biophys Sin (Shanghai) 2014 Jul 14;46(7):531-9. Epub 2014 May 14.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China

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July 2014

Catalytic dechlorination of 2,4-dichlorophenol by Ni/Fe nanoparticles prepared in the presence of ultrasonic irradiation.

Ultrason Sonochem 2014 Sep 13;21(5):1714-21. Epub 2014 Mar 13.

College of Environmental and Resource Sciences, Zhejiang University, Hangzhou 310058, People's Republic of China. Electronic address:

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September 2014

Mycobacterium bovis ornithine carbamoyltransferase, MB1684, induces proinflammatory cytokine gene expression by activating NF-κB in macrophages.

DNA Cell Biol 2014 May 25;33(5):311-9. Epub 2014 Feb 25.

State Key Laboratories for Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University , Beijing, China .

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May 2014

C-Abl tyrosine kinase mediates neurotoxic prion peptide-induced neuronal apoptosis via regulating mitochondrial homeostasis.

Mol Neurobiol 2014 Apr 8;49(2):1102-16. Epub 2014 Feb 8.

State Key Lab of Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, People's Republic of China,

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http://dx.doi.org/10.1007/s12035-014-8646-4DOI Listing
April 2014

PrP106-126 and Aβ 1-42 peptides induce BV-2 microglia chemotaxis and proliferation.

J Mol Neurosci 2014 Jan 13;52(1):107-16. Epub 2013 Nov 13.

National Animal TSE Lab, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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January 2014

Prokaryotic expression and functional analysis of the Mb1514 gene in Mycobacterium bovis.

Mol Cell Biochem 2014 Jan 20;385(1-2):43-52. Epub 2013 Oct 20.

National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, People's Republic of China.

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January 2014

Inhibition of phagocytosis reduced the classical activation of BV2 microglia induced by amyloidogenic fragments of beta-amyloid and prion proteins.

Acta Biochim Biophys Sin (Shanghai) 2013 Nov 20;45(11):973-8. Epub 2013 Sep 20.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

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November 2013

Decipher the mechanisms of rabbit's low susceptibility to prion infection.

Acta Biochim Biophys Sin (Shanghai) 2013 Nov 15;45(11):899-903. Epub 2013 Sep 15.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

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http://dx.doi.org/10.1093/abbs/gmt093DOI Listing
November 2013

Investigation of the effect of Mycobacterium bovis infection on bovine neutrophils functions.

Tuberculosis (Edinb) 2013 Nov 26;93(6):675-87. Epub 2013 Aug 26.

State Key Lab of Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, PR China; The State Key Lab of Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National TSE Lab, Beijing 100193, PR China; College of Veterinary Medicine, China Agricultural University, Beijing 100193, PR China. Electronic address:

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November 2013

Molecular cloning and sequence analysis of prion protein gene in Xiji donkey in China.

Gene 2013 Oct 15;529(2):345-50. Epub 2013 Aug 15.

State Key Laboratories for Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China; College of Agriculture, Ningxia University, Yinchuan 750021, China.

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October 2013

the AIM2 inflammasome is involved in macrophage activation during infection with virulent Mycobacterium bovis strain.

J Infect Dis 2013 Dec 30;208(11):1849-58. Epub 2013 Jul 30.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing.

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December 2013

PP2 and piceatannol inhibit PrP106-126-induced iNOS activation mediated by CD36 in BV2 microglia.

Acta Biochim Biophys Sin (Shanghai) 2013 Sep 9;45(9):763-72. Epub 2013 Jul 9.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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September 2013

Expression pattern of interferon-inducible transcriptional genes in neutrophils during bovine tuberculosis infection.

DNA Cell Biol 2013 Aug 29;32(8):480-6. Epub 2013 Jun 29.

State Key Lab of Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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August 2013

Using protein misfolding cyclic amplification generates a highly neurotoxic PrP dimer causing neurodegeneration.

J Mol Neurosci 2013 Nov 16;51(3):655-62. Epub 2013 Jun 16.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

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November 2013

Cellular prion protein (PrPC) of the neuron cell transformed to a PK-resistant protein under oxidative stress, comprising main mitochondrial damage in prion diseases.

J Mol Neurosci 2013 Sep 30;51(1):219-24. Epub 2013 May 30.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3739867PMC
September 2013

Expression and distribution of laminin receptor precursor/laminin receptor in rabbit tissues.

J Mol Neurosci 2013 Oct 30;51(2):591-601. Epub 2013 May 30.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

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October 2013

Inhibition of phagocytosis and lysosomal acidification suppresses neurotoxic prion peptide-induced NALP3 inflammasome activation in BV2 microglia.

J Neuroimmunol 2013 Jul 13;260(1-2):121-5. Epub 2013 May 13.

Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

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July 2013

Role of autophagy in prion protein-induced neurodegenerative diseases.

Acta Biochim Biophys Sin (Shanghai) 2013 Jun 3;45(6):494-502. Epub 2013 Mar 3.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

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June 2013

Interaction between misfolded PrP and the ubiquitin-proteasome system in prion-mediated neurodegeneration.

Acta Biochim Biophys Sin (Shanghai) 2013 Jun 28;45(6):477-84. Epub 2013 Feb 28.

State Key Laboratories for Agrobiotechnology, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

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June 2013

Molecular mechanisms of neurodegeneration mediated by dysfunctional subcellular organelles in transmissible spongiform encephalopathies.

Acta Biochim Biophys Sin (Shanghai) 2013 Jun 24;45(6):452-64. Epub 2013 Feb 24.

State Key Laboratories for Agrobiotechnology, China Agricultural University, Beijing 100193, China.

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June 2013

Cellular prion protein participates in the regulation of inflammatory response and apoptosis in BV2 microglia during infection with Mycobacterium bovis.

J Mol Neurosci 2013 Sep 24;51(1):118-26. Epub 2013 Jan 24.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

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September 2013

Reductive dechlorination of 2,4-dichlorophenol by Pd/Fe nanoparticles prepared in the presence of ultrasonic irradiation.

Ultrason Sonochem 2013 May 3;20(3):864-71. Epub 2012 Dec 3.

College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310032, PR China.

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May 2013

Prion protein participates in the regulation of classical and alternative activation of BV2 microglia.

J Neurochem 2013 Jan 15;124(2):168-74. Epub 2012 Nov 15.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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January 2013

Phagolysosome maturation of macrophages was reduced by PE_PGRS 62 protein expressing in Mycobacterium smegmatis and induced in IFN-γ priming.

Vet Microbiol 2012 Nov 18;160(1-2):117-25. Epub 2012 May 18.

The State Key Lab of Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National TSE Lab, College of Veterinary Medicine, China Agricultural University, Beijing 100193, PR China.

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November 2012

Antibody-mediated inhibition of integrin α5β1 blocks neurotoxic prion peptide PrP106-126-induced activation of BV2 microglia.

J Mol Neurosci 2012 Sep 31;48(1):248-52. Epub 2012 May 31.

The State Key Laboratories for Agrobiotechnology, Key Laboratory of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

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September 2012

The NALP3 inflammasome is involved in neurotoxic prion peptide-induced microglial activation.

J Neuroinflammation 2012 Jul 11;9:73. Epub 2012 Jul 11.

State Key Laboratories for Agrobiotechnology, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394218PMC
July 2012

Polymorphisms of SPRN (shadow of prion protein homology) in three breeds of sheep in China.

Virus Genes 2012 Jun 26;44(3):548-50. Epub 2012 Feb 26.

The State Key Lab of Agrobiotechnology, College of Veterinary Medicine, China Agricultural University, 2 Yuanmingyuan West Road, Beijing, 100193, China.

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June 2012

CD36 participates in PrP(106-126)-induced activation of microglia.

PLoS One 2012 26;7(1):e30756. Epub 2012 Jan 26.

National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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June 2012

Prion peptide PrP106-126 induces inducible nitric oxide synthase and proinflammatory cytokine gene expression through the activation of NF-κB in macrophage cells.

DNA Cell Biol 2012 May 9;31(5):833-8. Epub 2011 Dec 9.

State Key Laboratories for Agrobiotechnology, Key Lab of Animal Epidemiology and Zoonosis, Ministry of Agriculture, National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing, China.

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May 2012

Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport.

Proc Natl Acad Sci U S A 2011 Nov 31;108(45):18406-11. Epub 2011 Oct 31.

Laboratory of Immunology, Virginia-Maryland Regional College of Veterinary Medicine, and Maryland Pathogen Research Institute, University of Maryland, College Park, MD 20742, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215070PMC
November 2011

Cloning and polymorphism analysis of prion protein gene in domestic bactrian camel in China.

Gene 2012 Jan 13;491(2):256-9. Epub 2011 Oct 13.

National Animal Transmissible Spongiform Encephalopathy Laboratory, College of Veterinary Medicine, China Agricultural University, No.2 Yuanmingyuan West Road, Haidian District, Beijing 100193, China.

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January 2012