Deliang Guo

Deliang Guo

UNVERIFIED PROFILE

Are you Deliang Guo?   Register this Author

Register author
Deliang Guo

Deliang Guo

Publications by authors named "Deliang Guo"

Are you Deliang Guo?   Register this Author

31Publications

1255Reads

50Profile Views

Lgr5-mediated p53 Repression through PDCD5 leads to doxorubicin resistance in Hepatocellular Carcinoma.

Theranostics 2019 9;9(10):2967-2983. Epub 2019 May 9.

Department of General Surgery, Research Center of Digestive Diseases, Zhongnan Hospital of Wuhan University, Wuhan 430071, P.R. China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.7150/thno.30562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6568175PMC
May 2019

SCAP/SREBPs are Central Players in Lipid Metabolism and Novel Metabolic Targets in Cancer Therapy.

Curr Top Med Chem 2018 ;18(6):484-493

Department of Radiation Oncology, The Ohio State University James Comprehensive Cancer Center and College of Medicine, Columbus, OH 43210, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1568026618666180523104541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6214187PMC
July 2018

Lipid metabolism reprogramming and its potential targets in cancer.

Cancer Commun (Lond) 2018 05 21;38(1):27. Epub 2018 May 21.

Department of Radiation Oncology, The Ohio State University James Comprehensive Cancer Center and College of Medicine, Columbus, OH, 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s40880-018-0301-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993136PMC
May 2018

Lipid droplets, potential biomarker and metabolic target in glioblastoma.

Intern Med Rev (Wash D C) 2017 May;3(5)

Department of Radiation Oncology, The Ohio State University James Comprehensive Cancer Center and College of Medicine, Columbus, OH 43210, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5639724PMC
http://dx.doi.org/10.18103/imr.v3i5.443DOI Listing
May 2017

microRNA-29 mediates a novel negative feedback loop to regulate SCAP/SREBP-1 and lipid metabolism.

Authors:
Peng Ru Deliang Guo

RNA Dis 2017 20;4(1). Epub 2017 Mar 20.

Department of Radiation Oncology, The Ohio State University James Comprehensive Cancer Center and College of Medicine, Columbus, OH 43210, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.14800/rd.1525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5485916PMC
March 2017

Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated Lipogenesis.

Clin Cancer Res 2016 Nov 8;22(21):5337-5348. Epub 2016 Jun 8.

Department of Radiation Oncology, James Comprehensive Cancer Center & Arthur G James Cancer Hospital, The Ohio State Medical Center, Columbus, Ohio.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-15-2973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5093025PMC
November 2016

Analysis of SCAP N-glycosylation and Trafficking in Human Cells.

J Vis Exp 2016 11 8(117). Epub 2016 Nov 8.

Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center and College of Medicine;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3791/54709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5119469PMC
November 2016

Feedback Loop Regulation of SCAP/SREBP-1 by miR-29 Modulates EGFR Signaling-Driven Glioblastoma Growth.

Cell Rep 2016 08 28;16(6):1527-1535. Epub 2016 Jul 28.

Department of Radiation Oncology, James Comprehensive Cancer Center, College of Medicine, The Ohio State University, Columbus, OH 43210, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2016.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4981543PMC
August 2016

SCAP links glucose to lipid metabolism in cancer cells.

Authors:
Deliang Guo

Mol Cell Oncol 2016;3(2). Epub 2016 Jan 8.

Department of Radiation Oncology, The Ohio State University James Comprehensive Cancer Center, Columbus, Ohio 43210.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/23723556.2015.1132120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4822554PMC
January 2016

Targeting SREBP-1-driven lipid metabolism to treat cancer.

Curr Pharm Des 2014 ;20(15):2619-26

Department of Radiation Oncology, Ohio State University Comprehensive Cancer Center and Arthur G. James Cancer Hospital, Columbus, OH 43210, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148912PMC
http://dx.doi.org/10.2174/13816128113199990486DOI Listing
February 2015

Tumor metabolism of malignant gliomas.

Cancers (Basel) 2013 Nov 8;5(4):1469-84. Epub 2013 Nov 8.

Department of Radiation Oncology, Ohio State University Comprehensive Cancer Center & Arthur G James Cancer Hospital, Columbus, OH 43012, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cancers5041469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3875949PMC
November 2013

The mTOR kinase inhibitors, CC214-1 and CC214-2, preferentially block the growth of EGFRvIII-activated glioblastomas.

Clin Cancer Res 2013 Oct 12;19(20):5722-32. Epub 2013 Sep 12.

Authors' Affiliations: Laboratory of Molecular Pathology, Ludwig Institute for Cancer Research; Moores Cancer Center; University of California San Diego, La Jolla; Celgene Corporation, San Diego; Department of Neurological Surgery and Brain Tumor Research Center, University of California at San Francisco, San Francisco; California Institute of Technology, Pasadena; Henry Singleton Brain Tumor Program; Jonsson Comprehensive Cancer Center; Department of Neurology, David Geffen UCLA School of Medicine; Department of Molecular and Medical Pharmacology; UCLA Medical Scientist Training Program, University of California, Los Angeles, Los Angeles, California; Celgene Corporation, Summit, New Jersey; Department of Radiation Oncology, Ohio State University Comprehensive Cancer Center and Arthur G. James Cancer Hospital, Columbus, Ohio; Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, Verona, Italy; INSERM; Metabolomics Platform, Institut Gustave Roussy, Villejuif; Université Paris Descartes/Sorbonne Paris Cité; Equipe 11 labellisée Ligue contre le Cancer, Centre de Recherche des Cordeliers; and Pôle de Biologie, Hôpital Européen Georges Pompidou, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-13-0527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815450PMC
October 2013

[Anatomic study on perforating branch flap of medial vastus muscle and its clinical application].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2012 Sep;26(9):1091-4

Department of Orthopaedics, 89th Hospital of Chinese PLA, Weifang Shandong 261041, PR China.

View Article

Download full-text PDF

Source
September 2012

Single-cell proteomic chip for profiling intracellular signaling pathways in single tumor cells.

Proc Natl Acad Sci U S A 2012 Jan 27;109(2):419-24. Epub 2011 Dec 27.

Nanosystems Biology Cancer Center, Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

View Article

Download full-text PDF

Source
http://www.pnas.org/cgi/doi/10.1073/pnas.1110865109
Publisher Site
http://dx.doi.org/10.1073/pnas.1110865109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258586PMC
January 2012

The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis.

Proc Natl Acad Sci U S A 2009 Aug 22;106(31):12932-7. Epub 2009 Jul 22.

Department of Pathology & Laboratory Medicine, The David Geffen UCLA School of Medicine, Los Angeles, CA 90095, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0906606106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2714280PMC
August 2009

Angiotensin II up-regulates soluble epoxide hydrolase in vascular endothelium in vitro and in vivo.

Proc Natl Acad Sci U S A 2007 May 10;104(21):9018-23. Epub 2007 May 10.

Department of Physiology and Pathophysiology, Health Science Center, Key Laboratory of Molecular Cardiovascular Sciences of Education Ministry, Peking University, Beijing 100083, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.0703229104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885620PMC
May 2007

Regulation of endothelial cell cycle by laminar versus oscillatory flow: distinct modes of interactions of AMP-activated protein kinase and Akt pathways.

Circ Res 2007 Mar 1;100(4):564-71. Epub 2007 Feb 1.

Division of Biomedical Sciences, University of California, Riverside, CA 92521-0121, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/01.RES.0000259561.23876.c5DOI Listing
March 2007

Identification and characterization of a novel cytoplasm protein ICF45 that is involved in cell cycle regulation.

J Biol Chem 2004 Dec 29;279(51):53498-505. Epub 2004 Sep 29.

The Key Laboratory for Cell Proliferation and Regulation Biology of Ministry of Education, College of Life Science, Beijing Normal University, Beijing 100875, China.

View Article

Download full-text PDF

Source
http://www.jbc.org/lookup/doi/10.1074/jbc.M406737200
Publisher Site
http://dx.doi.org/10.1074/jbc.M406737200DOI Listing
December 2004