Degao Chen

Degao Chen

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Degao Chen

Degao Chen

Publications by authors named "Degao Chen"

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18Publications

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EZH2 regulates PD-L1 expression via HIF-1α in non-small cell lung cancer cells.

Biochem Biophys Res Commun 2019 Sep 19;517(2):201-209. Epub 2019 Jul 19.

Institute of Cancer, Xinqiao Hospital, Army Medical University, Chongqing, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.07.039DOI Listing
September 2019

Quercetin preferentially induces apoptosis in KRAS-mutant colorectal cancer cells via JNK signaling pathways.

Cell Biol Int 2019 Feb;43(2):117-124

West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu, P. R. China.

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http://dx.doi.org/10.1002/cbin.11055DOI Listing
February 2019

Circulating Tumor Microparticles Promote Lung Metastasis by Reprogramming Inflammatory and Mechanical Niches via a Macrophage-Dependent Pathway.

Cancer Immunol Res 2018 09 12;6(9):1046-1056. Epub 2018 Jul 12.

Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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http://dx.doi.org/10.1158/2326-6066.CIR-17-0574DOI Listing
September 2018

Fibrin Stiffness Mediates Dormancy of Tumor-Repopulating Cells via a Cdc42-Driven Tet2 Epigenetic Program.

Cancer Res 2018 07 15;78(14):3926-3937. Epub 2018 May 15.

National Key Laboratory of Medical Molecular Biology and Department of Immunology, Institute of Basic Medical Sciences, Clinical Immunology Center, Chinese Academy of Medical Sciences, Beijing, China.

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http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
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http://dx.doi.org/10.1158/0008-5472.CAN-17-3719DOI Listing
July 2018

Publisher Correction: Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype.

Nat Commun 2018 05 1;9(1):1808. Epub 2018 May 1.

Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, 100005, Beijing, China.

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http://www.nature.com/articles/s41467-018-04169-w
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http://dx.doi.org/10.1038/s41467-018-04169-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5931583PMC
May 2018

Tumor-Repopulating Cells Induce PD-1 Expression in CD8 T Cells by Transferring Kynurenine and AhR Activation.

Cancer Cell 2018 03;33(3):480-494.e7

Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences (CAMS) & Peking Union Medical College, Beijing 100005, China; Clinical Immunology Center, CAMS, Beijing 100005, China; Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.02.005DOI Listing
March 2018

Chloroquine modulates antitumor immune response by resetting tumor-associated macrophages toward M1 phenotype.

Nat Commun 2018 02 28;9(1):873. Epub 2018 Feb 28.

Department of Immunology and National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, 100005, China.

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http://dx.doi.org/10.1038/s41467-018-03225-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830447PMC
February 2018

A Pck1-directed glycogen metabolic program regulates formation and maintenance of memory CD8 T cells.

Nat Cell Biol 2018 01 11;20(1):21-27. Epub 2017 Dec 11.

Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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http://dx.doi.org/10.1038/s41556-017-0002-2DOI Listing
January 2018

Blockade of IDO-kynurenine-AhR metabolic circuitry abrogates IFN-γ-induced immunologic dormancy of tumor-repopulating cells.

Nat Commun 2017 05 10;8:15207. Epub 2017 May 10.

National Key Laboratory of Medical Molecular Biology &Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100005, China.

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http://dx.doi.org/10.1038/ncomms15207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5436221PMC
May 2017

Pre-instillation of tumor microparticles enhances intravesical chemotherapy of nonmuscle-invasive bladder cancer through a lysosomal pathway.

Biomaterials 2017 01 24;113:93-104. Epub 2016 Oct 24.

National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing 100005, China; Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan 430030, China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.10.036DOI Listing
January 2017

Oral delivery of tumor microparticle vaccines activates NOD2 signaling pathway in ileac epithelium rendering potent antitumor T cell immunity.

Oncoimmunology 2017 19;6(3):e1282589. Epub 2017 Jan 19.

Department of Immunology & National Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China; Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, China; Clinical Immunology Center, Chinese Academy of Medical Sciences, Beijing, China.

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http://dx.doi.org/10.1080/2162402X.2017.1282589DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5384362PMC
January 2017

BAY61-3606 potentiates the anti-tumor effects of TRAIL against colon cancer through up-regulating DR4 and down-regulating NF-κB.

Cancer Lett 2016 12 6;383(2):145-153. Epub 2016 Oct 6.

West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, 610041, Sichuan, China. Electronic address:

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http://dx.doi.org/10.1016/j.canlet.2016.10.002DOI Listing
December 2016

Delivery of oncolytic adenovirus into the nucleus of tumorigenic cells by tumor microparticles for virotherapy.

Biomaterials 2016 May 23;89:56-66. Epub 2016 Feb 23.

National Key Laboratory of Medical Molecular Biology & Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Beijing, 100005, China; Department of Biochemistry & Molecular Biology, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 430030, China. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.02.025DOI Listing
May 2016

Apoptosis induced by Ginkgo biloba (EGb761) in melanoma cells is Mcl-1-dependent.

PLoS One 2015 10;10(4):e0124812. Epub 2015 Apr 10.

Department of Forensic Genetics, School of Preclinical and Forensic Medicine, Sichuan University, Chengdu, P.R. China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0124812PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393283PMC
April 2016

Tumor cell-derived microparticles polarize M2 tumor-associated macrophages for tumor progression.

Oncoimmunology 2016 Apr 18;5(4):e1118599. Epub 2016 Feb 18.

Department of Biochemistry and Molecular Biology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; State Key Laboratory of Medical Molecular Biology and Department of Immunology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

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http://dx.doi.org/10.1080/2162402X.2015.1118599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839324PMC
April 2016

[Human caspase-14 expression in malignant melanoma and its significance].

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2014 Nov;30(11):1180-3

Department of Pathophysiology, School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China.

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November 2014