Deepak Srivastava

Deepak Srivastava

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Deepak Srivastava

Deepak Srivastava

Publications by authors named "Deepak Srivastava"

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96Publications

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Δ-tetrahydrocannabinol and 2-AG decreases neurite outgrowth and differentially affects ERK1/2 and Akt signaling in hiPSC-derived cortical neurons.

Mol Cell Neurosci 2020 Mar 7;103:103463. Epub 2020 Jan 7.

Department of Basic and Clinical Neuroscience, The Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry Psychology and Neuroscience, King's College London, London SE5 8AF, UK; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mcn.2019.103463DOI Listing
March 2020

Estradiol reverses excitatory synapse loss in a cellular model of neuropsychiatric disorders.

Transl Psychiatry 2020 Jan 21;10(1):16. Epub 2020 Jan 21.

Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, SE5 9RT, UK.

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http://dx.doi.org/10.1038/s41398-020-0682-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7026123PMC
January 2020

Exchange protein directly activated by cAMP 2 is required for corticotropin-releasing hormone-mediated spine loss.

Eur J Neurosci 2019 Oct 9;50(7):3108-3114. Epub 2019 Jul 9.

Department of Physiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1111/ejn.14487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821562PMC
October 2019

Dynamic Chromatin Targeting of BRD4 Stimulates Cardiac Fibroblast Activation.

Circ Res 2019 Sep 14;125(7):662-677. Epub 2019 Aug 14.

From the Department of Medicine, Division of Cardiology (M.S.S., R.A.B., M.B.F., A.S.R., B.Y.E., K.A.K., M.A.C., K.S., M.P.Y.L., T.A.M.), University of Colorado Anschutz Medical Campus, Aurora.

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http://dx.doi.org/10.1161/CIRCRESAHA.119.315125DOI Listing
September 2019

Loss of EPAC2 alters dendritic spine morphology and inhibitory synapse density.

Mol Cell Neurosci 2019 07 4;98:19-31. Epub 2019 May 4.

Department of Physiology, Institute of Psychiatry, Psychology and Neuroscience, King's College London, 125 Coldharbour Lane, London SE5 8NU, UK; Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, 303 E. Chicago Avenue, Chicago, IL 60611, USA. Electronic address:

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http://dx.doi.org/10.1016/j.mcn.2019.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6639166PMC
July 2019

The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells.

Biol Psychiatry 2019 07 30;86(2):120-130. Epub 2019 Mar 30.

Department of Basic & Clinical Neuroscience, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom; Medical Research Council Centre for Neurodevelopmental Disorders, King's College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2019.03.977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614717PMC
July 2019

Context-Specific Transcription Factor Functions Regulate Epigenomic and Transcriptional Dynamics during Cardiac Reprogramming.

Cell Stem Cell 2019 07;25(1):87-102.e9

Gladstone Institutes, San Francisco, CA 94158, USA; Departments of Pediatrics and Biochemistry & Biophysics, University of California, San Francisco, CA 94143, USA; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2019.06.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632093PMC
July 2019

Premature MicroRNA-1 Expression Causes Hypoplasia of the Cardiac Ventricular Conduction System.

Front Physiol 2019 18;10:235. Epub 2019 Mar 18.

Gladstone Institute of Cardiovascular Disease, San Francisco, CA, United States.

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http://dx.doi.org/10.3389/fphys.2019.00235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6431665PMC
March 2019

Cyto-nuclear shuttling of afadin is required for rapid estradiol-mediated modifications of histone H3.

Neuropharmacology 2018 12 27;143:153-162. Epub 2018 Sep 27.

Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, UK; MRC Centre for Neurodevelopmental Disorders, King's College London, London, SE5 9RT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2018.09.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6277849PMC
December 2018

The Psychiatric Cell Map Initiative: A Convergent Systems Biological Approach to Illuminating Key Molecular Pathways in Neuropsychiatric Disorders.

Cell 2018 07;174(3):505-520

Quantitative Biosciences Institute (QBI), University of California, San Francisco, San Francisco, CA 94143, USA; Gladstone Institutes, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94143, USA; Helen Diller Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.06.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247911PMC
July 2018

Estradiol and the Development of the Cerebral Cortex: An Unexpected Role?

Front Neurosci 2018 25;12:245. Epub 2018 May 25.

Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, London, United Kingdom.

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http://dx.doi.org/10.3389/fnins.2018.00245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5981095PMC
May 2018

Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration.

Cell 2018 03 1;173(1):104-116.e12. Epub 2018 Mar 1.

Gladstone Institute of Cardiovascular Disease and Roddenberry Stem Cell Center, San Francisco, CA 94158, USA; Department of Pediatrics, University of California San Francisco, San Francisco, CA 94158, USA; Department of Biochemistry & Biophysics, University of California San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.02.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973786PMC
March 2018

Studies on the structural changes during curing of epoxy and its blend with CTBN.

Spectrochim Acta A Mol Biomol Spectrosc 2018 Jan 3;188:99-105. Epub 2017 Jul 3.

School of Chemical Technology - Department of Plastic Technology, H. B. Technical University (Formerly H. B. Technological Institute), Kanpur 208 002, U.P., India.

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http://dx.doi.org/10.1016/j.saa.2017.06.066DOI Listing
January 2018

Estradiol modulates the efficacy of synaptic inhibition by decreasing the dwell time of GABA receptors at inhibitory synapses.

Proc Natl Acad Sci U S A 2017 10 16;114(44):11763-11768. Epub 2017 Oct 16.

AstraZeneca-Tufts Laboratory for Basic and Translational Neuroscience, Tufts University School of Medicine, Boston, MA 02111;

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http://dx.doi.org/10.1073/pnas.1705075114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676881PMC
October 2017

Psychosis Risk Candidate ZNF804A Localizes to Synapses and Regulates Neurite Formation and Dendritic Spine Structure.

Biol Psychiatry 2017 07 15;82(1):49-61. Epub 2016 Sep 15.

Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, London; MRC Centre for Neurodevelopmental Disorders, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London; United Kingdom.

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http://dx.doi.org/10.1016/j.biopsych.2016.08.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482321PMC
July 2017

Multi-Imaging Method to Assay the Contractile Mechanical Output of Micropatterned Human iPSC-Derived Cardiac Myocytes.

Circ Res 2017 May 11;120(10):1572-1583. Epub 2017 Apr 11.

From the Department of Mechanical Engineering (A.J.S.R., O.S., B.L.P.), Department of Molecular and Cellular Physiology (by courtesy) (B.L.P.), Department of Bioengineering (by courtesy) (B.L.P.), and Stanford Cardiovascular Institute (A.J.S.R., B.L.P.), Stanford University, CA; Gladstone Institute of Cardiovascular Disease, San Francisco, CA (A.J.S.R., M.A.M., Y.-S.A., B.R.C., D.S.); Roddenberry Stem Cell Center at Gladstone, San Francisco, CA (Y.-S.A., D.S.); Departments of Pediatrics and Biochemistry & Biophysics (D.S.), Department of Cellular and Molecular Pharmacology (B.R.C.), California Institute for Quantitative Biosciences, QB3 (B.R.C.), and Department of Medicine and Cellular and Molecular Pharmacology (B.R.C.), University of California, San Francisco.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.310363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5491345PMC
May 2017

Chemical Enhancement of In Vitro and In Vivo Direct Cardiac Reprogramming.

Circulation 2017 Mar 10;135(10):978-995. Epub 2016 Nov 10.

From Gladstone Institute of Cardiovascular Disease and Roddenberry Center for Stem Cell Biology and Medicine, San Francisco, CA (T.M.A.M., N.R.S., E.C.B., E.R., Y.H., K.P., Y.-S.A., P.Y., H.W., S.T., S.D., K.N.I., D.S.); Institute of Cardiovascular Sciences, University of Manchester, UK (T.M.A.M.); Faculty of Pharmacy, Zagazig University, Egypt (T.M.A.M.); and Departments of Radiology (S.M.), Pharmaceutical Chemistry (S.D.), Pediatrics (K.N.I., D.S.), and Biochemistry and Biophysics (D.S.), University of California San Francisco.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340593PMC
March 2017

Control of Dendritic Spine Morphological and Functional Plasticity by Small GTPases.

Neural Plast 2016 18;2016:3025948. Epub 2016 Feb 18.

Department of Basic and Clinical Neuroscience, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 9RT, UK.

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http://dx.doi.org/10.1155/2016/3025948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4775798PMC
December 2016

Molecular Mechanisms of Dendritic Spine Development and Plasticity.

Neural Plast 2016 3;2016:2078121. Epub 2016 Apr 3.

Department of Neuroscience, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.

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http://dx.doi.org/10.1155/2016/2078121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834162PMC
December 2016

Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis.

Cell 2016 Dec;167(7):1734-1749.e22

Gladstone Institute of Cardiovascular Disease and Roddenberry Center for Stem Cell Biology and Medicine, San Francisco, CA 94158, USA; Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.11.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5180611PMC
December 2016

Effect of biophysical cues on reprogramming to cardiomyocytes.

Biomaterials 2016 10 23;103:1-11. Epub 2016 Jun 23.

Department of Bioengineering, University of California, Berkeley, USA; UC Berkeley & UCSF Joint Graduate Program in Bioengineering, Berkeley, San Francisco, USA; Department of Bioengineering, University of California, Los Angeles, USA. Electronic address:

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http://dx.doi.org/10.1016/j.biomaterials.2016.06.034DOI Listing
October 2016

The long noncoding RNA Chaer defines an epigenetic checkpoint in cardiac hypertrophy.

Nat Med 2016 10 12;22(10):1131-1139. Epub 2016 Sep 12.

Division of Molecular Medicine, Department of Anesthesiology, David Geffen School of Medicine, University of California at Los Angeles (UCLA), Los Angeles, California, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053883PMC
http://dx.doi.org/10.1038/nm.4179DOI Listing
October 2016

Genome-wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis-regulation of BORCS7, AS3MT, and NT5C2 in the human brain.

Am J Med Genet B Neuropsychiatr Genet 2016 09 22;171(6):806-14. Epub 2016 Mar 22.

Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1002/ajmg.b.32445DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4988385PMC
September 2016

In Vivo Cellular Reprogramming: The Next Generation.

Cell 2016 Sep;166(6):1386-1396

Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1016/j.cell.2016.08.055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6234007PMC
September 2016

Sarcomeres and Cardiac Growth: Tension in the Relationship.

Trends Mol Med 2016 07 26;22(7):530-533. Epub 2016 May 26.

Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA; Department of Pediatrics, Division of Cardiology, UCSF School of Medicine, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molmed.2016.05.001DOI Listing
July 2016

Conversion of human fibroblasts into functional cardiomyocytes by small molecules.

Science 2016 Jun 28;352(6290):1216-20. Epub 2016 Apr 28.

Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA. Department of Pharmaceutical Chemistry, University of California-San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1126/science.aaf1502DOI Listing
June 2016

Expandable Cardiovascular Progenitor Cells Reprogrammed from Fibroblasts.

Cell Stem Cell 2016 Mar;18(3):368-81

Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA; Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2016.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826660PMC
March 2016

Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses.

PLoS One 2015 24;10(3):e0121765. Epub 2015 Mar 24.

Molecular Biosciences and Institute for Cellular and Molecular Biology, University of Texas, Austin, Texas, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0121765PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372598PMC
February 2016

Heart disease modelling adds a Notch to its belt.

Nat Cell Biol 2016 Jan;18(1):3-5

Roddenberry Center for Stem Cell Biology and Medicine, Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, California 94158, USA, and the Departments of Pediatrics and Biochemistry &Biophysics, University of California, San Francisco, 16th Street, San Francisco, California 94143, USA.

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http://dx.doi.org/10.1038/ncb3294DOI Listing
January 2016

Efficient CRISPR/Cas9-Based Genome Engineering in Human Pluripotent Stem Cells.

Curr Protoc Hum Genet 2016 Jan 1;88:21.4.1-21.4.23. Epub 2016 Jan 1.

Gladstone Institute of Cardiovascular Disease, San Francisco, California.

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http://dx.doi.org/10.1002/0471142905.hg2104s88DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4726454PMC
January 2016

Direct reprogramming of fibroblasts into cardiomyocytes for cardiac regenerative medicine.

Circ J 2015 16;79(2):245-54. Epub 2015 Jan 16.

Heart and Vascular Research Center, MetroHealth Campus of Case Western Reserve University, Cleveland, OH, USA; Gladstone Institute of Cardiovascular Disease, USA; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, San Francisco, CA, USA.

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http://dx.doi.org/10.1253/circj.CJ-14-1372DOI Listing
November 2015

Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness.

Proc Natl Acad Sci U S A 2015 Oct 28;112(41):12705-10. Epub 2015 Sep 28.

Department of Mechanical Engineering, Stanford University, Stanford, CA 94305; Stanford Cardiovascular Institute, Stanford University, Stanford, CA 94305; Department of Molecular and Cellular Physiology, Stanford University, Stanford, CA 94305

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http://dx.doi.org/10.1073/pnas.1508073112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4611612PMC
October 2015

Practical Integration-Free Episomal Methods for Generating Human Induced Pluripotent Stem Cells.

Curr Protoc Hum Genet 2015 Oct 6;87:21.2.1-21.2.21. Epub 2015 Oct 6.

Gladstone Institute of Cardiovascular Disease, San Francisco, California.

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http://dx.doi.org/10.1002/0471142905.hg2102s87DOI Listing
October 2015

Recent advances in direct cardiac reprogramming.

Curr Opin Genet Dev 2015 Oct 24;34:77-81. Epub 2015 Oct 24.

Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1016/j.gde.2015.09.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674326PMC
October 2015

Utilizing induced pluripotent stem cells (iPSCs) to understand the actions of estrogens in human neurons.

Horm Behav 2015 Aug 2;74:228-42. Epub 2015 Jul 2.

Department of Basic and Clinical Neuroscience, Cell and Behaviour Unit, The James Black Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 8AF, UK. Electronic address:

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http://dx.doi.org/10.1016/j.yhbeh.2015.06.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4579404PMC
August 2015

Characterisation of neurons derived from a cortical human neural stem cell line CTX0E16.

Stem Cell Res Ther 2015 Aug 22;6:149. Epub 2015 Aug 22.

Department of Basic and Clinical Neuroscience, Institute of Psychiatry Psychology & Neuroscience, King's College London, London, SE5 8AF, UK.

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http://stemcellres.com/content/6/1/149
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http://dx.doi.org/10.1186/s13287-015-0136-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546258PMC
August 2015

NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium.

J Mol Cell Cardiol 2015 Jul 12;84:13-23. Epub 2015 Apr 12.

Gladstone Institute of Cardiovascular Disease and University of California, San Francisco, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2015.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4468000PMC
July 2015

microRNAs as Developmental Regulators.

Cold Spring Harb Perspect Biol 2015 Jul 1;7(7):a008144. Epub 2015 Jul 1.

Gladstone Institute of Cardiovascular Disease and Departments of Pediatrics, Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California 94158.

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http://dx.doi.org/10.1101/cshperspect.a008144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484971PMC
July 2015

An interview with Deepak Srivastava.

Development 2015 Jun;142(12):2083-4

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http://dx.doi.org/10.1242/dev.125468DOI Listing
June 2015

Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state.

Stem Cell Reports 2013 22;1(3):235-47. Epub 2013 Aug 22.

Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA ; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, San Francisco, CA 94158, USA ; Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94158, USA ; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1016/j.stemcr.2013.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3849259PMC
May 2015

Rapid modulation of synaptogenesis and spinogenesis by 17β-estradiol in primary cortical neurons.

Front Cell Neurosci 2015 14;9:137. Epub 2015 Apr 14.

Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London London, UK.

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http://dx.doi.org/10.3389/fncel.2015.00137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396386PMC
April 2015

Human disease modeling reveals integrated transcriptional and epigenetic mechanisms of NOTCH1 haploinsufficiency.

Cell 2015 Mar;160(6):1072-86

Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, San Francisco, CA 94158, USA; Program in Developmental and Stem Cell Biology, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.02.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359747PMC
March 2015

RNA sequencing of mouse sinoatrial node reveals an upstream regulatory role for Islet-1 in cardiac pacemaker cells.

Circ Res 2015 Feb 26;116(5):797-803. Epub 2015 Jan 26.

From the Gladstone Institute of Cardiovascular Disease, San Francisco, CA (V.V., G.G., M.E., D.S.); and Division of Cardiology, Departments of Medicine (V.V., G.G., R.C.D.), Pediatrics (D.S.), and Biochemistry and Biophysics (R.C.D., D.S.), Institute for Human Genetics, California Institute for Quantitative Biosciences (R.C.D.), and Cardiovascular Research Institute (V.V., G.G., M.E., R.C.D.), University of California, San Francisco.

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http://dx.doi.org/10.1161/CIRCRESAHA.116.305913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344860PMC
February 2015

Molecular signature of rapid estrogen regulation of synaptic connectivity and cognition.

Front Neuroendocrinol 2015 Jan 23;36:72-89. Epub 2014 Aug 23.

Department of Basic and Clinical Neuroscience, The James Black Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London SE5 9NU, UK. Electronic address:

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http://dx.doi.org/10.1016/j.yfrne.2014.08.001DOI Listing
January 2015

Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia.

Hum Mol Genet 2015 Jan 10;24(2):424-35. Epub 2014 Sep 10.

Department of Molecular Biology and

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http://dx.doi.org/10.1093/hmg/ddu458DOI Listing
January 2015

Scaffold protein X11α interacts with kalirin-7 in dendrites and recruits it to Golgi outposts.

J Biol Chem 2014 Dec 5;289(51):35517-29. Epub 2014 Nov 5.

From the Departments of Physiology and Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611,

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http://dx.doi.org/10.1074/jbc.M114.587709DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271236PMC
December 2014

Oxygen: double-edged sword in cardiac function and repair.

Circ Res 2014 Oct;115(10):824-5

From the Gladstone Institute of Cardiovascular Disease and Roddenberry Stem Cell Center at Gladstone Institutes, San Francisco, CA (Y.-S.A., D.S.); and Departments of Pediatrics and Biochemistry and Biophysics, University of California, San Francisco (Y.-S.A., D.S.)

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http://dx.doi.org/10.1161/CIRCRESAHA.114.305322DOI Listing
October 2014

Specification of the mouse cardiac conduction system in the absence of Endothelin signaling.

Dev Biol 2014 Sep 19;393(2):245-254. Epub 2014 Jul 19.

Cardiovascular Research Institute, University of California, San Francisco, CA 94158-2517, USA; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158-2517, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ydbio.2014.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143461PMC
September 2014

Deepak Srivastava: follows his heart to study the heart.

Circ Res 2014 Aug;115(5):481-3

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http://dx.doi.org/10.1161/CIRCRESAHA.114.304793DOI Listing
August 2014

Hippocampal biomarkers of fear memory in an animal model of generalized anxiety disorder.

Behav Brain Res 2014 Apr 23;263:34-45. Epub 2014 Jan 23.

Laboratory of Neurobiology of the Retina, Program of Neurobiology, Institute of Biophysics, Universidade Federal do Rio de Janeiro (UFRJ), Av Carlos Chagas Filho, 373, CCS, Bloco G, Sala C-031 - Cidade Universitária, CEP:21941-902 Rio de Janeiro, RJ, Brazil(1). Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2014.01.012DOI Listing
April 2014

Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4.

Cell Rep 2014 Mar 20;6(5):951-60. Epub 2014 Feb 20.

Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, San Francisco, CA 94158, USA; Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.01.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4004339PMC
March 2014

Insights into rapid modulation of neuroplasticity by brain estrogens.

Pharmacol Rev 2013 27;65(4):1318-50. Epub 2013 Sep 27.

Department of Neuroscience & Centre for the Cellular Basis of Behaviour, 125 Coldharbour Lane, The James Black Centre, Institute of Psychiatry, King's College London, London, SE5 9NU, UK.

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http://dx.doi.org/10.1124/pr.111.005272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799233PMC
February 2014

Congenital heart disease: entering a new era of human genetics.

Circ Res 2014 Feb;114(4):598-9

From the Gladstone Institute of Cardiovascular Disease, San Francisco, CA (B.G.B., D.S.); and Departments of Pediatrics (B.G.B., D.S.), Biochemistry and Biophysics (D.S.), and Cardiovascular Research Institute (B.G.B.), University of California, San Francisco.

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http://dx.doi.org/10.1161/CIRCRESAHA.113.303060DOI Listing
February 2014

The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of prodifferentiation genes.

Cell Stem Cell 2014 Jan 14;14(1):40-52. Epub 2013 Nov 14.

Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA; Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, San Francisco, CA 94158, USA; Center for iPS Cell Research and Application, Kyoto University, Kyoto 606-8507, Japan; Department of Anatomy, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2013.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3982312PMC
January 2014

Cardiac reprogramming: from mouse toward man.

Curr Opin Genet Dev 2013 Oct 28;23(5):574-8. Epub 2013 Aug 28.

Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA; Roddenberry Center for Stem Cell Biology and Medicine, San Francisco, CA 94158, USA; Department of Pediatrics, University of California, San Francisco, CA 94158, USA; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94158, USA. Electronic address:

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http://dx.doi.org/10.1016/j.gde.2013.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782415PMC
October 2013

Direct cardiac reprogramming: from developmental biology to cardiac regeneration.

Circ Res 2013 Sep;113(7):915-21

From the McAllister Heart Institute, Department of Pathology and Laboratory Medicine, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill.

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http://dx.doi.org/10.1161/CIRCRESAHA.112.300625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869462PMC
September 2013

Fibronectin mediates mesendodermal cell fate decisions.

Development 2013 Jun;140(12):2587-96

Gladstone Institute of Cardiovascular Disease, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1242/dev.089052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666385PMC
June 2013

Reprogramming of mouse fibroblasts into cardiomyocyte-like cells in vitro.

Nat Protoc 2013 Jun 30;8(6):1204-15. Epub 2013 May 30.

Gladstone Institute of Cardiovascular Disease, San Francisco, CA, USA.

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http://dx.doi.org/10.1038/nprot.2013.067DOI Listing
June 2013

Fending for a Braveheart.

EMBO J 2013 May 22;32(9):1211-3. Epub 2013 Mar 22.

Gladstone Institute of Cardiovascular Disease, Roddenberry Center for Stem Cell Biology and Medicine, and Department of Pediatrics, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1038/emboj.2013.71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3642680PMC
May 2013

Small solutions to big problems: microRNAs for cardiac regeneration.

Circ Res 2013 May;112(11):1412-4

Gladstone Institute of Cardiovascular Disease and Roddenberry Center for Stem Cell Biology and Medicine at Gladstone, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.113.301409DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760376PMC
May 2013

Spatiotemporal regulation of an Hcn4 enhancer defines a role for Mef2c and HDACs in cardiac electrical patterning.

Dev Biol 2013 Jan 23;373(1):149-62. Epub 2012 Oct 23.

Gladstone Institute of Cardiovascular Disease, University of California, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1016/j.ydbio.2012.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510001PMC
January 2013

Sonography as an objective tool for monitoring serial corrections and detecting spurious corrections in clubfoot: a review.

Foot (Edinb) 2012 Dec 15;22(4):315-8. Epub 2012 Sep 15.

Department of Orthopaedics, M.L.B. Medical College, Jhansi, Uttar Pradesh, India.

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http://dx.doi.org/10.1016/j.foot.2012.08.002DOI Listing
December 2012

Stem cells in the land of the rising sun: ISSCR 2012.

Cell Stem Cell 2012 Nov;11(5):607-14

Department of Biological Chemistry, Jonsson Comprehensive Cancer Center, Molecular Biology Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90024, USA.

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http://dx.doi.org/10.1016/j.stem.2012.10.003DOI Listing
November 2012

Afadin is required for maintenance of dendritic structure and excitatory tone.

J Biol Chem 2012 Oct 4;287(43):35964-74. Epub 2012 Sep 4.

Department of Physiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1074/jbc.M112.363358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476264PMC
October 2012

A role for RNA post-transcriptional regulation in satellite cell activation.

Skelet Muscle 2012 Oct 9;2(1):21. Epub 2012 Oct 9.

Department of Molecular, Cellular, and Developmental Biology, University of Colorado, Boulder, CO, 80309, USA.

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http://dx.doi.org/10.1186/2044-5040-2-21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563611PMC
October 2012

Cardiac repair with thymosin β4 and cardiac reprogramming factors.

Ann N Y Acad Sci 2012 Oct;1270:66-72

Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA.

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http://doi.wiley.com/10.1111/j.1749-6632.2012.06696.x
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http://dx.doi.org/10.1111/j.1749-6632.2012.06696.xDOI Listing
October 2012

Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo.

PLoS Genet 2012 10;8(5):e1002690. Epub 2012 May 10.

Center for Cardiovascular and Pulmonary Research and the Heart Center, Nationwide Children's Hospital, The Ohio State University, Columbus, Ohio, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1002690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349729PMC
September 2012

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes.

Nature 2012 May;485(7400):593-8

1Gladstone Institute of Cardiovascular Disease, San Francisco, California 94158, USA.

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http://dx.doi.org/10.1038/nature11044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369107PMC
May 2012