Deepak Lala

Deepak Lala

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Deepak Lala

Deepak Lala

Publications by authors named "Deepak Lala"

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Effect of short-term liver X receptor activation on epidermal barrier features in mild to moderate atopic dermatitis: A randomized controlled trial.

Ann Allergy Asthma Immunol 2018 06 19;120(6):631-640.e11. Epub 2018 Mar 19.

Department of Dermatology and the Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Laboratory for Investigative Dermatology, The Rockefeller University, New York, New York. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10811206183021
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http://dx.doi.org/10.1016/j.anai.2018.03.013DOI Listing
June 2018

Influence of sub-chronic selective 11β-hydroxysteroid dehydrogenase 1 inhibition on the hypothalamic-pituitary-adrenal axis in female cynomolgus monkeys.

Eur J Pharmacol 2016 Oct 5;789:68-74. Epub 2016 Jul 5.

Vitae Pharmaceuticals, 502 West Office Center Drive, Fort Washington, PA 19034, United States.

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http://dx.doi.org/10.1016/j.ejphar.2016.07.004DOI Listing
October 2016

The medicinal chemistry of liver X receptor (LXR) modulators.

J Med Chem 2014 Sep 28;57(17):7182-205. Epub 2014 May 28.

Vitae Pharmaceuticals Inc. , 502 West Office Center Drive, Fort Washington, Pennsylvania 19034, United States.

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http://dx.doi.org/10.1021/jm500442zDOI Listing
September 2014

Regulation of sphingomyelin phosphodiesterase acid-like 3A gene (SMPDL3A) by liver X receptors.

Mol Pharmacol 2012 Oct 18;82(4):719-27. Epub 2012 Jul 18.

Discovery Biology, Vitae Pharmaceuticals, Inc., Fort Washington, Pennsylvania, USA.

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http://dx.doi.org/10.1124/mol.112.078865DOI Listing
October 2012

An activin receptor-like kinase 5 inhibitor reduces collagen deposition in a rat dermal incision wound healing model.

Plast Reconstr Surg 2011 Nov;128(5):451e-459e

Pfizer Worldwide Research and Development, Pfizer, Inc., Groton, CT 06340, USA.

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http://dx.doi.org/10.1097/PRS.0b013e31822b65c7DOI Listing
November 2011

The liver X receptors.

Authors:
Deepak S Lala

Curr Opin Investig Drugs 2005 Sep;6(9):934-43

Pfizer Global Research and Development, Ann Arbor, MI 48105, USA.

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September 2005

Molecular mechanisms of mineralocorticoid receptor antagonism by eplerenone.

Mini Rev Med Chem 2005 Aug;5(8):709-18

Department of Genomics and Biotechnology, Pfizer Inc., St. Louis, MO 63017, USA.

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http://dx.doi.org/10.2174/1389557054553811DOI Listing
August 2005

The ligand-dependent interaction of mineralocorticoid receptor with coactivator and corepressor peptides suggests multiple activation mechanisms.

Mol Endocrinol 2005 Jun 10;19(6):1460-73. Epub 2005 Mar 10.

St. Louis Laboratories, Biological Sciences, Pfizer Global Research & Development, Missouri 63017, USA.

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http://dx.doi.org/10.1210/me.2004-0537DOI Listing
June 2005

Liver X receptors and atherosclerosis.

Authors:
Deepak S Lala

IDrugs 2004 Jun;7(6):563-9

Pfizer Global Research and Development, Building 26 Room 261N, 2800 Plymouth Road, Ann Arbor, MI 48105, USA.

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June 2004

Repression of p65 transcriptional activation by the glucocorticoid receptor in the absence of receptor-coactivator interactions.

Mol Endocrinol 2004 Jan 9;18(1):53-62. Epub 2003 Oct 9.

Department of Biochemistry and Molecular Biology, Pharmacia Corp., St. Louis, Missouri 63198, USA.

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http://dx.doi.org/10.1210/me.2002-0373DOI Listing
January 2004

Liver X receptors interact with corepressors to regulate gene expression.

Mol Endocrinol 2003 Jun 27;17(6):1019-26. Epub 2003 Mar 27.

Department of Biotechnology, Pharmacia Corp., St. Louis, Missouri 63017, USA.

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http://dx.doi.org/10.1210/me.2002-0399DOI Listing
June 2003

Multiplexing nuclear receptors for agonist identification in a cell-based reporter gene high-throughput screen.

J Biomol Screen 2003 Jun;8(3):239-46

Discovery Technologies, Pharmacia Corp., Kalamazoo, MI 49007, USA.

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http://dx.doi.org/10.1177/1087057103008003001DOI Listing
June 2003

The hypolipidemic natural product guggulsterone acts as an antagonist of the bile acid receptor.

Mol Endocrinol 2002 Jul;16(7):1590-7

Department of Biotechnology, Pharmacia Corp., St. Louis, Missouri 63198, USA.

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http://dx.doi.org/10.1210/mend.16.7.0894DOI Listing
July 2002

Steroidogenic factor 1: an essential mediator of endocrine development.

Recent Prog Horm Res 2002 ;57:19-36

Department of Internal Medicine and Pharmacology, University of Texas Southwestern Medical Center, Dallas 75390, USA.

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http://dx.doi.org/10.1210/rp.57.1.19DOI Listing
June 2002

Induction of human liver X receptor alpha gene expression via an autoregulatory loop mechanism.

Mol Endocrinol 2002 Mar;16(3):506-14

Department of Biotechnology, Mail Zone AA305E, Pharmacia Corp., St. Louis, Missouri 63198, USA.

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http://dx.doi.org/10.1210/mend.16.3.0789DOI Listing
March 2002