Publications by authors named "Deepak L Bhatt"

100Publications

Cardiopulmonary Hemodynamics in Pulmonary Hypertension and Heart Failure: JACC Review Topic of the Week.

J Am Coll Cardiol 2020 Dec;76(22):2671-2681

Division of Cardiology, Department of Medicine, Medical University of South Carolina, Charleston, South Carolina. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2020.10.007DOI Listing
December 2020

Coronary Artery Calcium to Improve the Efficiency of Randomized Controlled Trials in Primary Cardiovascular Prevention.

JACC Cardiovasc Imaging 2020 Nov 18. Epub 2020 Nov 18.

Division of Cardiovascular Prevention and Wellness, Department of Cardiology, Houston Methodist DeBakey Heart & Vascular Center, Houston, Texas; Center for Outcomes Research, Houston Methodist, Houston, Texas; Johns Hopkins Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland.

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http://dx.doi.org/10.1016/j.jcmg.2020.10.016DOI Listing
November 2020

New Decade, New FDA Guidance for Diabetes Drug Development: Lessons Learned and Future Directions.

J Am Coll Cardiol 2020 Nov;76(21):2522-2526

Ciccarone Center for the Prevention of Cardiovascular Disease, Johns Hopkins University School of Medicine, Baltimore, Maryland; Division of Cardiology, Department of Medicine, Weill Cornell Medical College-Qatar, Education City, Doha, Qatar. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2020.09.590DOI Listing
November 2020

Regulation of Cardiovascular Therapies During the COVID-19 Public Health Emergency.

J Am Coll Cardiol 2020 Nov;76(21):2517-2521

Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: https://twitter.com/DLBHATTMD.

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http://dx.doi.org/10.1016/j.jacc.2020.09.594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7669239PMC
November 2020

Vascular Risk Reduction in Obesity through Reduced Granulocyte Burden and Improved Angiogenic Monocyte Content following Bariatric Surgery.

Cell Rep Med 2020 May 19;1(2):100018. Epub 2020 May 19.

Division of Cardiac Surgery, Keenan Research Centre for Biomedical Science and Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.xcrm.2020.100018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7659601PMC
May 2020

Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure.

N Engl J Med 2020 Nov 16. Epub 2020 Nov 16.

From Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, Boston (D.L.B., C.P.C.); Colorado Prevention Center Clinical Research and Department of Medicine, Division of Cardiovascular Medicine, University of Colorado Anschutz Medical Campus, Aurora (M.S.); State University of New York Downstate School of Public Health, Brooklyn (M.S.); Université de Paris, French Alliance for Cardiovascular Trials, Assistance Publique-Hôpitaux de Paris, Hôpital Bichat, INSERM Unité 1148 (P.G.S.), and Paris Sorbonne University and Groupe Hospitalier Paris Saint Joseph (M.K.), Paris; Li Ka Shing Knowledge Institute (L.A.L., S.V.) and the Divisions of Endocrinology and Metabolism (L.A.L.) and Cardiac Surgery (S.V.), St. Michael's Hospital, and the Departments of Medicine and Nutritional Sciences (L.A.L) and Surgery and Pharmacology and Toxicology (S.V.), University of Toronto, Toronto; University of Texas Southwestern Medical Center and Parkland Health and Hospital System, Dallas (D.K.M.), and Lexicon Pharmaceuticals, The Woodlands (P.L.) - both in Texas; Vanderbilt University, Nashville (J.B.L.); the Division of Endocrinology, Diabetes, and Clinical Nutrition, Oregon Health and Science University, Portland (M.C.R.); University of Groningen-University Medical Center Groningen, Groningen, the Netherlands (A.A.V); Azienda Socio Sanitaria Territoriale Spedali Civili and University of Brescia, Brescia, Italy (M.M.); Karolinska Institutet, Stockholm (L.H.L.); Yale University, New Haven, CT (J.M.T.); Georgetown University, Washington, DC (C.S.W.); Wroclaw Medical University, Wroclaw, Poland (P.P.); Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (R.D.L.); and the University of Michigan, Ann Arbor (B.P.).

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http://dx.doi.org/10.1056/NEJMoa2030183DOI Listing
November 2020

Sotagliflozin in Patients with Diabetes and Chronic Kidney Disease.

N Engl J Med 2020 Nov 16. Epub 2020 Nov 16.

From Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, Boston (D.L.B., C.P.C., B.M.S.); Colorado Prevention Center Clinical Research and Department of Medicine, Division of Cardiovascular Medicine, University of Colorado Anschutz Medical Campus, Aurora (M.S.); the State University of New York Downstate School of Public Health, Brooklyn (M.S.); the University of Michigan, Ann Arbor (B.P.); Li Ka Shing Knowledge Institute and the Division of Endocrinology and Metabolism, St. Michael's Hospital, and the Departments of Medicine and Nutritional Sciences, University of Toronto (L.A.L.), and the Division of Nephrology (D.Z.I.C.) and the Cardiovascular Division, Department of Medicine, Women's College Hospital and Peter Munk Cardiac Centre (J.A.U.), University Health Network, University of Toronto - all in Toronto; the University of Texas Southwestern Medical Center and Parkland Health and Hospital System, Dallas (D.K.M.), and Lexicon Pharmaceuticals, The Woodlands (P.L.) - both in Texas; Vanderbilt University Medical Center, Nashville (J.B.L., J.P.D.); the Division of Endocrinology, Diabetes, and Clinical Nutrition, Oregon Health and Science University, Portland (M.C.R.); the Section of Endocrinology, Yale School of Medicine, New Haven, CT (S.E.I.); Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City, Kansas City (M.N.K.); the School of Life and Health Sciences, Aston University, Birmingham (C.J.B.), and the Imperial Centre for Cardiovascular Disease Prevention, Department of Primary Care and Public Health, Imperial College London, London (K.K.R.) - both in the United Kingdom; the Department of Medicine, Estudios Clínicos Latinoamérica, Instituto Cardiovascular de Rosario, Rosario, Argentina (R.D.); Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC (R.D.L.); and Université de Paris, French Alliance for Cardiovascular Trials, Assistance Publique-Hôpitaux de Paris, Hôpital Bichat, INSERM Unité 1148, Paris (P.G.S.).

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http://dx.doi.org/10.1056/NEJMoa2030186DOI Listing
November 2020

A questionnaire survey for improving awareness of rheumatic heart disease among school-aged children in India.

Indian Heart J 2020 Sep - Oct;72(5):410-415. Epub 2020 Aug 9.

Brigham and Women's Hospital Heart & Vascular Center, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.ihj.2020.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670277PMC
August 2020

Secondary prevention of cardiovascular diseases in India: Findings from registries and large cohorts.

Indian Heart J 2020 Sep - Oct;72(5):337-344. Epub 2020 Sep 6.

Health Policy, Quality & Informatics Program, Michael E. DeBakey Veterans Affairs Medical Center Health Services Research and Development Center for Innovations Section of Cardiovascular Research, Department of Medicine, Baylor College of Medicine, Houston, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ihj.2020.08.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7670271PMC
September 2020

Increased prevalence of myocardial injury in patients with SARS-CoV-2 viremia.

Am J Med 2020 Nov 9. Epub 2020 Nov 9.

Heart and Vascular Center, Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2020.09.046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7654293PMC
November 2020

Applying to Medical School in the COVID-19 Era.

Mayo Clin Proc 2020 11 19;95(11):2317-2319. Epub 2020 Aug 19.

Brigham and Women's Hospital Heart & Vascular Center, Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2020.08.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7437476PMC
November 2020

A Revolution in Omega-3 Fatty Acid Research.

J Am Coll Cardiol 2020 Nov;76(18):2098-2101

Brigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, Boston, Massachusetts; Elucida Research LLC, Beverly, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2020.09.005DOI Listing
November 2020

The Road to Approval: a Perspective on the Role of Icosapent Ethyl in Cardiovascular Risk Reduction.

Curr Diab Rep 2020 Oct 23;20(11):65. Epub 2020 Oct 23.

Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s11892-020-01343-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7584545PMC
October 2020

Beyond cardiovascular medicine: potential future uses of icosapent ethyl.

Eur Heart J Suppl 2020 Oct 6;22(Suppl J):J54-J64. Epub 2020 Oct 6.

CGH Medical Center, 101 East Miller Road, Sterling, IL 61081, USA.

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http://dx.doi.org/10.1093/eurheartj/suaa119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537800PMC
October 2020

Mineral oil: safety and use as placebo in REDUCE-IT and other clinical studies.

Eur Heart J Suppl 2020 Oct 6;22(Suppl J):J34-J48. Epub 2020 Oct 6.

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1093/eurheartj/suaa117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537802PMC
October 2020

Mechanisms of action, efficacy, and safety of icosapent ethyl: from bench to bedside.

Authors:
Deepak L Bhatt

Eur Heart J Suppl 2020 Oct 6;22(Suppl J):J1-J2. Epub 2020 Oct 6.

Brigham and Women's Hospital Heart & Vascular Center, Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/eurheartj/suaa114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7537798PMC
October 2020

Incidence, Characteristics, Predictors, and Outcomes of Surgical Explantation After Transcatheter Aortic Valve Replacement.

J Am Coll Cardiol 2020 Oct;76(16):1848-1859

Division of Cardiac Surgery, Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2020.08.048DOI Listing
October 2020

Systolic Blood Pressure and Outcomes in Older Patients with HFpEF and Hypertension.

Am J Med 2020 Sep 30. Epub 2020 Sep 30.

Veterans Affairs Medical Center, Washington, DC; George Washington University, Washington, DC; Georgetown University, Washington, DC. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2020.08.030DOI Listing
September 2020

Trends in Costs and Risk Factors of 30-Day Readmissions for Transcatheter Aortic Valve Implantation.

Am J Cardiol 2020 Dec 28;137:89-96. Epub 2020 Sep 28.

Division of Cardiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2020.09.041DOI Listing
December 2020

"Cholesterol-Years" for ASCVD Risk Prediction and Treatment.

J Am Coll Cardiol 2020 Sep;76(13):1517-1520

Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts. Electronic address: https://twitter.com/DLBhattMD.

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http://dx.doi.org/10.1016/j.jacc.2020.08.004DOI Listing
September 2020

Impact of chronic kidney disease on in-hospital outcomes and readmission rate after edge-to-edge transcatheter mitral valve repair.

Catheter Cardiovasc Interv 2020 Aug 15. Epub 2020 Aug 15.

Division of Cardiology, Department of Internal Medicine, Southern Illinois University School of Medicine, Springfield, Illinois.

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http://dx.doi.org/10.1002/ccd.29188DOI Listing
August 2020

Impact of expanded FDA indication for icosapent ethyl on enhanced cardiovascular residual risk reduction.

Future Cardiol 2020 Sep 22. Epub 2020 Sep 22.

Brigham & Women's Hospital Heart & Vascular Center & Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.2217/fca-2020-0106DOI Listing
September 2020

TAVR and the Kidney: Is This the Beginning of a Beautiful Friendship?

J Am Coll Cardiol 2020 Sep;76(12):1422-1424

Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.jacc.2020.08.015DOI Listing
September 2020

Generalizability of Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial in patients with a history of coronary artery bypass graft surgery.

Curr Opin Cardiol 2020 Sep 8. Epub 2020 Sep 8.

Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Québec City, Québec, Canada.

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http://dx.doi.org/10.1097/HCO.0000000000000800DOI Listing
September 2020

Lifelong Aspirin for All in the Secondary Prevention of Chronic Coronary Syndrome: Still Sacrosanct or Is Reappraisal Warranted?

Circulation 2020 Oct 4;142(16):1579-1590. Epub 2020 Sep 4.

School of Medicine, National University of Ireland Galway, Ireland(R.W.C., P.W.J.C.S., W.W., J.W.M.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.045695DOI Listing
October 2020

Eligibility for Low-Dose Rivaroxaban Based on the COMPASS Trial: Insights from the Veterans Affairs Healthcare System.

Cardiovasc Drugs Ther 2020 Sep 3. Epub 2020 Sep 3.

Health Policy, Quality & Informatics Program, Michael E. DeBakey Veterans Affairs Medical Center Health Services Research & Development Center for Innovations, Houston, TX, USA.

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http://dx.doi.org/10.1007/s10557-020-07061-2DOI Listing
September 2020

The COVID-19 pandemic: a catalyst to improve clinical trials.

Nat Rev Cardiol 2020 11;17(11):673-675

Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41569-020-00439-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7461742PMC
November 2020

Antiplatelet patterns and outcomes in patients with atrial fibrillation not prescribed an anticoagulant after stroke.

Int J Cardiol 2020 Dec 14;321:88-94. Epub 2020 Aug 14.

Section of Cardiac Electrophysiology, Division of Cardiology, University of California San Diego, La Jolla, CA, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2020.08.011DOI Listing
December 2020

Genetic Variation in Cardiometabolic Traits and Medication Targets and the Risk of Hypertensive Disorders of Pregnancy.

Circulation 2020 Aug 17;142(7):711-713. Epub 2020 Aug 17.

Cardiology Division (M.C.H., K.A., M.J.W., A.A.S., N.S.S., P.N.), Massachusetts General Hospital, Harvard Medical School, Boston.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.120.047936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436942PMC
August 2020

Dapagliflozin and Cardiac, Kidney, and Limb Outcomes in Patients With and Without Peripheral Artery Disease in DECLARE-TIMI 58.

Circulation 2020 Aug 3;142(8):734-747. Epub 2020 Aug 3.

TIMI (Thrombolysis in Myocardial Infarction) Study Group, Division of Cardiovascular Medicine, Brigham and Women's Hospital Heart and Harvard Medical School, Boston, MA (M.P.B., S.D.W., T.A.Z., D.L.B., E.L.G., M.S.S.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.044775DOI Listing
August 2020

Federal judge invalidates icosapent ethyl patents - but on the basis of a common statistical mistake.

Nat Biotechnol 2020 08;38(8):939-941

Duke University School of Medicine, Durham, NC, USA.

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http://dx.doi.org/10.1038/s41587-020-0616-yDOI Listing
August 2020

Sex Differences in Case Fatality Rate of COVID-19: Insights From a Multinational Registry.

Mayo Clin Proc 2020 08 29;95(8):1613-1620. Epub 2020 May 29.

Department of Medicine, Division of Cardiology, Brigham and Women's Hospital Heart & Vascular Center, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1016/j.mayocp.2020.05.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7256502PMC
August 2020

The Landscape of Cardiovascular Clinical Trials in the United States Initiated Before and During COVID-19.

J Am Heart Assoc 2020 09 27;9(18):e018274. Epub 2020 Jul 27.

Brigham and Women's Hospital Heart & Vascular Center Harvard Medical School Boston MA.

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http://dx.doi.org/10.1161/JAHA.120.018274DOI Listing
September 2020

Prevalence and Outcomes of Acute Ischemic Stroke Among Patients ≤50 Years of Age With Laboratory Confirmed COVID-19 Infection.

Am J Cardiol 2020 09 14;130:169-170. Epub 2020 Jun 14.

Department of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2020.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293843PMC
September 2020

Safety and efficacy of drug eluting stents vs bare metal stents in patients with atrial fibrillation: A systematic review and meta-analysis.

Thromb Res 2020 Nov 9;195:128-135. Epub 2020 Jul 9.

University of Connecticut/Hartford Hospital Evidence-based Practice Center, Hartford, CT, USA; School of Medicine, Universidad Peruana de Ciencias Aplicadas (UPC), Lima, Peru. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2020.07.010DOI Listing
November 2020

Association Between Universal Masking in a Health Care System and SARS-CoV-2 Positivity Among Health Care Workers.

JAMA 2020 Jul 14. Epub 2020 Jul 14.

Division of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jama.2020.12897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7362190PMC
July 2020

Differential effect of ticagrelor on irreversible harms in diabetes - Authors' reply.

Lancet 2020 07;396(10244):93-94

French Alliance for Cardiovascular Trials, Département Hospitalo-Universitaire FIRE, AP-HP, Hôpital Bichat, Université de Paris, Institut National de la Santé et de la Recherche Médicale, Paris, France; National Heart and Lung Institute, Imperial College, Royal Brompton Hospital, London, UK.

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http://dx.doi.org/10.1016/S0140-6736(20)30479-7DOI Listing
July 2020

Quantifying the Impact of Care Fragmentation on Outcomes After Transcatheter Aortic Valve Implantation.

Am J Cardiol 2020 08 15;128:113-119. Epub 2020 May 15.

Division of Cardiac Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2020.05.005DOI Listing
August 2020

Influence of Influenza Infection on In-Hospital Acute Myocardial Infarction Outcomes.

Am J Cardiol 2020 09 7;130:7-14. Epub 2020 Jun 7.

Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2020.05.045DOI Listing
September 2020

Pregnancy as a Cardiac Stress Test: Time to Include Obstetric History in Cardiac Risk Assessment?

J Am Coll Cardiol 2020 Jul;76(1):68-71

Department of Exercise Science, Arnold School of Public Health, University of South Carolina, Columbia, South Carolina.

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http://dx.doi.org/10.1016/j.jacc.2020.05.017DOI Listing
July 2020

Management of acute myocardial injury in patients with confirmed or suspected COVID-19.

Atherosclerosis 2020 07 16;305:58-60. Epub 2020 Jun 16.

Cardiovascular Division, University of Nebraska Medical Center, Omaha, NE, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2020.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7296319PMC
July 2020

Early post-percutaneous coronary intervention chest pain: A nationwide survey on interventional cardiologists' perspective.

Cardiovasc Revasc Med 2020 May 16. Epub 2020 May 16.

Department of Internal Medicine, East Tennessee State University, Johnson City, TN, USA. Electronic address:

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http://dx.doi.org/10.1016/j.carrev.2020.05.011DOI Listing
May 2020

Self-treatment for acute coronary syndrome: why not?

Eur Heart J 2020 Jun;41(23):2144-2145

Brigham and Women's Hospital Heart and Vascular Center, Harvard Medical School (Professor), 75 Francis Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/eurheartj/ehaa302DOI Listing
June 2020

Periodontal Inflammation and the Risk of Cardiovascular Disease.

Curr Atheroscler Rep 2020 Jun 8;22(7):28. Epub 2020 Jun 8.

Department of Cardiology, John Ochsner Heart and Vascular Institute, Ochsner Clinical School-UQ School of Medicine, New Orleans, LA, 20814, USA.

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http://dx.doi.org/10.1007/s11883-020-00848-6DOI Listing
June 2020

Special Article - Acute myocardial injury in patients hospitalized with COVID-19 infection: A review.

Prog Cardiovasc Dis 2020 Sep - Oct;63(5):682-689. Epub 2020 Jun 6.

Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.pcad.2020.05.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274977PMC
June 2020