Deepak Kaushal

Deepak Kaushal

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Deepak Kaushal

Publications by authors named "Deepak Kaushal"

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sensor kinase DosS modulates the autophagosome in a DosR-independent manner.

Commun Biol 2019 20;2:349. Epub 2019 Sep 20.

1Tulane National Primate Research Center, Covington, LA 70433 USA.

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http://dx.doi.org/10.1038/s42003-019-0594-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754383PMC
September 2019

Friend or Foe: The Protective and Pathological Roles of Inducible Bronchus-Associated Lymphoid Tissue in Pulmonary Diseases.

J Immunol 2019 May;202(9):2519-2526

Department of Molecular Microbiology, Washington University School of Medicine in St. Louis, St. Louis, MO 63110;

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http://dx.doi.org/10.4049/jimmunol.1801135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481307PMC
May 2019

Mucosal-activated invariant T cells do not exhibit significant lung recruitment and proliferation profiles in macaques in response to infection with Mycobacterium tuberculosis CDC1551.

Tuberculosis (Edinb) 2019 05 26;116S:S11-S18. Epub 2019 Apr 26.

Tulane National Primate Research Centre, Covington, LA, USA; Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2019.04.006DOI Listing
May 2019

The comeback kid: BCG.

Authors:
Deepak Kaushal

J Infect Dis 2019 Mar 15. Epub 2019 Mar 15.

Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX.

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https://academic.oup.com/jid/advance-article/doi/10.1093/inf
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http://dx.doi.org/10.1093/infdis/jiz117DOI Listing
March 2019

Opening Pandora's Box: Mechanisms of Mycobacterium tuberculosis Resuscitation.

Trends Microbiol 2018 02 11;26(2):145-157. Epub 2017 Sep 11.

Divisions of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, LA, USA; Department of Microbiology & Immunology, Tulane University School of Medicine, New Orleans, LA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tim.2017.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5794633PMC
February 2018

Toward Tuberculosis Vaccine Development: Recommendations for Nonhuman Primate Study Design.

Infect Immun 2018 02 22;86(2). Epub 2018 Jan 22.

Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA

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http://dx.doi.org/10.1128/IAI.00776-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5778361PMC
February 2018

Pathogenesis and Animal Models of Post-Primary (Bronchogenic) Tuberculosis, A Review.

Pathogens 2018 Feb 6;7(1). Epub 2018 Feb 6.

Department of Pathology and Laboratory Medicine, University of Texas Health Sciences Center at Houston, Houston, TX 77030, USA.

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http://dx.doi.org/10.3390/pathogens7010019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874745PMC
February 2018

Translational Research in the Nonhuman Primate Model of Tuberculosis.

ILAR J 2017 12;58(2):151-159

Tulane National Primate Research Center, Covington, Louisiana.

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http://dx.doi.org/10.1093/ilar/ilx015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279141PMC
December 2017

Nonpathologic Infection of Macaques by an Attenuated Mycobacterial Vaccine Is Not Reactivated in the Setting of HIV Co-Infection.

Am J Pathol 2017 Dec 19;187(12):2811-2820. Epub 2017 Sep 19.

Tulane National Primate Research Center, Covington, Louisiana; Center for Biomedical Research Excellence, Louisiana State University School of Veterinary Medicine, Baton Rouge, Louisiana; Department of Pathobiological Sciences, Louisiana State University School of Veterinary Medicine, Baton Rouge, Louisiana. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029440173036
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http://dx.doi.org/10.1016/j.ajpath.2017.08.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718104PMC
December 2017

Sequencing-relative to hybridization-based transcriptomics approaches better define Mycobacterium tuberculosis stress-response regulons.

Tuberculosis (Edinb) 2016 12 28;101S:S9-S17. Epub 2016 Sep 28.

Divisions of Bacteriology & Parasitology, Tulane National Primate Research Center, Covington LA, USA; Department of Microbiology & Immunology, Tulane University School of Medicine, New Orleans, LA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2016.09.020DOI Listing
December 2016

Mycobacterium tuberculosis.

J Immunol Res 2015 4;2015:857598. Epub 2015 Aug 4.

Department of Basic Medical Sciences, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA 91766-1854, USA.

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http://dx.doi.org/10.1155/2015/857598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539972PMC
August 2016

In-Vivo Gene Signatures of Mycobacterium tuberculosis in C3HeB/FeJ Mice.

PLoS One 2015 13;10(8):e0135208. Epub 2015 Aug 13.

Tulane National Primate Research Center, Covington, Louisiana, United States of America; Microbiology and Immunology, Tulane University School of Medicine, New Orleans, Louisiana, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135208PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535907PMC
May 2016

A tuberculosis ontology for host systems biology.

Tuberculosis (Edinb) 2015 Sep 30;95(5):570-4. Epub 2015 Jun 30.

Knowledge Synthesis Inc., Berkeley, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tube.2015.05.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554888PMC
September 2015

The Mycobacterium tuberculosis Rv2745c plays an important role in responding to redox stress.

PLoS One 2014 4;9(4):e93604. Epub 2014 Apr 4.

Divisions of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, Louisiana, United States of America; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, Louisiana, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0093604PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976341PMC
June 2015

LAG3 expression in active Mycobacterium tuberculosis infections.

Am J Pathol 2015 Mar 27;185(3):820-33. Epub 2014 Dec 27.

Division of Bacteriology, Tulane National Primate Research Center, Covington, Louisiana; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, Louisiana. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2014.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4348466PMC
March 2015

The Mycobacterium tuberculosis Clp gene regulator is required for in vitro reactivation from hypoxia-induced dormancy.

J Biol Chem 2015 Jan 24;290(4):2351-67. Epub 2014 Nov 24.

From the Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, Louisiana 70433

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http://dx.doi.org/10.1074/jbc.M114.615534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303686PMC
January 2015

Role of TNF in the altered interaction of dormant Mycobacterium tuberculosis with host macrophages.

PLoS One 2014 17;9(4):e95220. Epub 2014 Apr 17.

Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, Louisiana, United States of America; Department of Microbiology and Immunology, Tulane University School of Medicine, New Orleans, Louisiana, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0095220PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3990579PMC
December 2014

Microdissection approaches in tuberculosis research.

J Med Primatol 2014 Oct 28;43(5):294-7. Epub 2014 Aug 28.

Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, LA, USA; Veterinary Pathology (T32) Training Program, Tulane National Primate Research Center, Covington, LA, USA.

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http://dx.doi.org/10.1111/jmp.12141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4311393PMC
October 2014

A novel microdissection approach to recovering mycobacterium tuberculosis specific transcripts from formalin fixed paraffin embedded lung granulomas.

J Vis Exp 2014 Jun 5(88). Epub 2014 Jun 5.

Bacteriology and Parasitology, Tulane National Primate Research Center; Microbiology and Immunology, Tulane National Primate Research Center.

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http://dx.doi.org/10.3791/51693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186700PMC
June 2014

Unexpected role for IL-17 in protective immunity against hypervirulent Mycobacterium tuberculosis HN878 infection.

PLoS Pathog 2014 May 15;10(5):e1004099. Epub 2014 May 15.

Department of Pediatrics, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America; Department of Molecular Microbiology, Washington University in St. Louis, St. Louis, Missouri, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022785PMC
May 2014

Expression levels of 10 candidate genes in lung tissue of vaccinated and TB-infected cynomolgus macaques.

J Med Primatol 2013 Jun;42(3):161-4

Graduate Group in Comparative Pathology, University of California, Davis, CA 95616, USA.

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June 2013

Granuloma correlates of protection against tuberculosis and mechanisms of immune modulation by Mycobacterium tuberculosis.

J Infect Dis 2013 Apr 18;207(7):1115-27. Epub 2012 Dec 18.

Division of Microbiology, Tulane National Primate Research Center, Covington, LA 70433, USA.

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http://dx.doi.org/10.1093/infdis/jis778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633457PMC
April 2013

Role of interleukin 6 in innate immunity to Mycobacterium tuberculosis infection.

J Infect Dis 2013 Apr 28;207(8):1253-61. Epub 2013 Jan 28.

Divisions of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, LA 70433, USA.

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http://dx.doi.org/10.1093/infdis/jit037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693587PMC
April 2013

CXCR5⁺ T helper cells mediate protective immunity against tuberculosis.

J Clin Invest 2013 Feb 2;123(2):712-26. Epub 2013 Jan 2.

Department of Pediatrics, Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1172/JCI65728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3561804PMC
February 2013

Eicosanoids, prostaglandins, and the progression of tuberculosis.

Authors:
Deepak Kaushal

J Infect Dis 2012 Dec 2;206(12):1803-5. Epub 2012 Oct 2.

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http://dx.doi.org/10.1093/infdis/jis611DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502378PMC
December 2012

Increased expression of P-glycoprotein and doxorubicin chemoresistance of metastatic breast cancer is regulated by miR-298.

Am J Pathol 2012 Jun 19;180(6):2490-503. Epub 2012 Apr 19.

Department of Pathology and Laboratory Medicine, Tulane University Health Sciences Center, New Orleans, LA 70112, USA.

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http://dx.doi.org/10.1016/j.ajpath.2012.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378910PMC
June 2012

Aerosolized gentamicin reduces the burden of tuberculosis in a murine model.

Antimicrob Agents Chemother 2012 Feb 5;56(2):883-6. Epub 2011 Dec 5.

Divisions of Microbiology, Tulane National Primate Research Center, Covington, Louisiana, USA.

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http://dx.doi.org/10.1128/AAC.05633-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264242PMC
February 2012

Faithful Experimental Models of Human Infection.

Mycobact Dis 2012 Feb;2

Tuberculosis Research Program, Division of Bacteriology & Parasitology, Tulane National Primate Research Center, Covington, LA, 70433, USA.

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http://dx.doi.org/10.4172/2161-1068.1000e108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3908825PMC
February 2012

Interleukin-10 alters effector functions of multiple genes induced by Borrelia burgdorferi in macrophages to regulate Lyme disease inflammation.

Infect Immun 2011 Dec 26;79(12):4876-92. Epub 2011 Sep 26.

Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana, USA.

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http://dx.doi.org/10.1128/IAI.05451-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232652PMC
December 2011

Mycobacterium tuberculosis MT2816 encodes a key stress-response regulator.

J Infect Dis 2010 Sep;202(6):943-53

Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, Louisiana 70433, USA.

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http://dx.doi.org/10.1086/654820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052882PMC
September 2010

Transcriptional reprogramming in nonhuman primate (rhesus macaque) tuberculosis granulomas.

PLoS One 2010 Aug 31;5(8):e12266. Epub 2010 Aug 31.

Divisions of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, Louisiana, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012266PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2930844PMC
August 2010

Genetic requirements for the survival of tubercle bacilli in primates.

J Infect Dis 2010 Jun;201(11):1743-52

Division of Bacteriology and Parasitology, Tulane National Primate Research Center, 18703 Three Rivers Road, Covington, LA 70433, USA.

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http://dx.doi.org/10.1086/652497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862080PMC
June 2010

A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising anti-mycobacterial thioridazine.

PLoS One 2010 Apr 8;5(4):e10069. Epub 2010 Apr 8.

Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, Louisiana, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010069PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2851646PMC
April 2010

Microglia are mediators of Borrelia burgdorferi-induced apoptosis in SH-SY5Y neuronal cells.

PLoS Pathog 2009 Nov 13;5(11):e1000659. Epub 2009 Nov 13.

Division of Bacteriology & Parasitology, Tulane National Primate Research Center, Tulane University Health Sciences Center, Louisiana, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1000659DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2771360PMC
November 2009

Functional genomics reveals extended roles of the Mycobacterium tuberculosis stress response factor sigmaH.

J Bacteriol 2009 Jun 17;191(12):3965-80. Epub 2009 Apr 17.

Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Covington, LA 70433, USA.

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http://jb.asm.org/cgi/doi/10.1128/JB.00064-09
Publisher Site
http://dx.doi.org/10.1128/JB.00064-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2698404PMC
June 2009

The antibiotics doxycycline and minocycline inhibit the inflammatory responses to the Lyme disease spirochete Borrelia burgdorferi.

J Infect Dis 2009 May;199(9):1379-88

Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Tulane University, Covington, LA 70433, USA.

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http://dx.doi.org/10.1086/597807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3697124PMC
May 2009

Interaction of the Lyme disease spirochete Borrelia burgdorferi with brain parenchyma elicits inflammatory mediators from glial cells as well as glial and neuronal apoptosis.

Am J Pathol 2008 Nov 2;173(5):1415-27. Epub 2008 Oct 2.

Division of Bacteriology and Parasitology, Tulane National Primate Research Center, Tulane University, Covington, LA 70433, USA.

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http://dx.doi.org/10.2353/ajpath.2008.080483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570132PMC
November 2008

Closing the phenotypic gap between transformed neuronal cell lines in culture and untransformed neurons.

J Neurosci Methods 2008 Sep 10;174(1):31-41. Epub 2008 Jul 10.

Division of Bacteriology & Parasitology, Tulane National Primate Research Center, 18703 Three Rivers Road, Covington, LA 70433, USA.

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http://dx.doi.org/10.1016/j.jneumeth.2008.06.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2586177PMC
September 2008

Long-term in vitro expansion alters the biology of adult mesenchymal stem cells.

Cancer Res 2008 Jun;68(11):4229-38

Division of Gene Therapy, Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana 70433, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-07-5272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2713721PMC
June 2008

Evaluation of IFN-gamma effects on apoptosis and gene expression in neuroblastoma--preclinical studies.

Biochim Biophys Acta 2006 Oct 9;1763(10):1000-10. Epub 2006 Aug 9.

Department of Hematology-Oncology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

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http://dx.doi.org/10.1016/j.bbamcr.2006.06.014DOI Listing
October 2006

Vancomycin stress response in a sensitive and a tolerant strain of Streptococcus pneumoniae.

J Bacteriol 2005 Dec;187(23):8205-10

Departments of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1128/JB.187.23.8205-8210.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1291284PMC
December 2005

An overview of Spotfire for gene-expression studies.

Curr Protoc Hum Genet 2005 May;Chapter 11:Unit 11.9

St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1002/0471142905.hg1109s45DOI Listing
May 2005

Revising the role of the pneumococcal vex-vncRS locus in vancomycin tolerance.

J Bacteriol 2004 Dec;186(24):8463-71

Department of Infectious Diseases, 332 N. Lauderdale St., Memphis, TN 38105, USA.

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http://dx.doi.org/10.1128/JB.186.24.8463-8471.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC532416PMC
December 2004

Microarray analysis of pneumococcal gene expression during invasive disease.

Infect Immun 2004 Oct;72(10):5582-96

Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

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http://dx.doi.org/10.1128/IAI.72.10.5582-5596.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC517545PMC
October 2004

Analyzing and visualizing expression data with Spotfire.

Curr Protoc Bioinformatics 2004 Oct;Chapter 7:Unit 7.9

St Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1002/0471250953.bi0709s7DOI Listing
October 2004

An overview of Spotfire for gene-expression studies.

Curr Protoc Bioinformatics 2004 Sep;Chapter 7:Unit 7.7

St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1002/0471250953.bi0707s6DOI Listing
September 2004

Loading and preparing data for analysis in spotfire.

Curr Protoc Bioinformatics 2004 Sep;Chapter 7:Unit 7.8

Hartwell Center for Bioinformatics and Biotechnology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.

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http://dx.doi.org/10.1002/0471250953.bi0708s6DOI Listing
September 2004