Deepak K Rajpal

Deepak K Rajpal

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Deepak K Rajpal

Deepak K Rajpal

Publications by authors named "Deepak K Rajpal"

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29Publications

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The Comparison of Skin Transcriptomes Confirms Canine Atopic Dermatitis Is a Natural Homologue to the Human Disease.

J Invest Dermatol 2019 Apr 28;139(4):968-971. Epub 2018 Oct 28.

Computational Biology, Target Sciences, GlaxoSmithKline, Collegeville, Pennsylvania, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.10.018DOI Listing
April 2019

Could advances in representation learning in Artificial Intelligence provide the new paradigm for data integration in drug discovery?

Expert Opin Drug Discov 2019 Mar 30;14(3):191-194. Epub 2019 Jan 30.

a Computational Biology , GlaxoSmithKline R&D , Collegeville , PA , USA.

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https://www.tandfonline.com/doi/full/10.1080/17460441.2019.1
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http://dx.doi.org/10.1080/17460441.2019.1573811DOI Listing
March 2019

The essentiality of drug targets: an analysis of current literature and genomic databases.

Drug Discov Today 2019 02 13;24(2):544-550. Epub 2018 Nov 13.

Computational Biology, GSK R&D, Collegeville, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S13596446183014
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http://dx.doi.org/10.1016/j.drudis.2018.11.002DOI Listing
February 2019

Multi-omics integration reveals molecular networks and regulators of psoriasis.

BMC Syst Biol 2019 01 14;13(1). Epub 2019 Jan 14.

Department of Integrative Biology and Physiology, University of California, Los Angeles, 610 Charles E. Young Dr. East, Los Angeles, CA, 90095, USA.

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https://bmcsystbiol.biomedcentral.com/articles/10.1186/s1291
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http://dx.doi.org/10.1186/s12918-018-0671-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332659PMC
January 2019

Uncovering new disease indications for G-protein coupled receptors and their endogenous ligands.

BMC Bioinformatics 2018 Oct 1;19(1):345. Epub 2018 Oct 1.

Computational Biology, Target Sciences, GlaxoSmithKline, Collegeville, PA, 19426, USA.

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https://bmcbioinformatics.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/s12859-018-2392-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6167889PMC
October 2018

Gut microbiome differences between metformin- and liraglutide-treated T2DM subjects.

Endocrinol Diabetes Metab 2018 Jan 28;1(1):e00009. Epub 2017 Dec 28.

Computational Biology Target Sciences GlaxoSmithKline Research and Development (R&D) Collegeville PA USA.

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http://dx.doi.org/10.1002/edm2.9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360918PMC
January 2018

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness.

Nat Commun 2017 07 12;8:16015. Epub 2017 Jul 12.

MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Cambridge CB2 0QQ, UK.

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http://dx.doi.org/10.1038/ncomms16015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5510175PMC
July 2017

Network-Based Identification and Prioritization of Key Regulators of Coronary Artery Disease Loci.

Arterioscler Thromb Vasc Biol 2016 05 10;36(5):928-41. Epub 2016 Mar 10.

From the Department of Integrative Biology and Physiology, University of California, Los Angeles (Y.Z., Q.M., X.Y.); and Target Sciences Computational Biology (US), GSK, King of Prussia, PA (J.C., J.M.F., D.K.R.).

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http://dx.doi.org/10.1161/ATVBAHA.115.306725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5576868PMC
May 2016

Human microbial metabolites as a source of new drugs.

Drug Discov Today 2016 Apr 22;21(4):692-8. Epub 2016 Feb 22.

Computational Biology, Target Sciences, R&D, GlaxoSmithKline, 1250 S. Collegeville Road, Collegeville, PA 19426-0989, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2016.02.009DOI Listing
April 2016

Mining emerging biomedical literature for understanding disease associations in drug discovery.

Methods Mol Biol 2014 ;1159:171-206

Computational Biology, GlaxoSmithKline R&D, Research Triangle Park, North Carolina, NC, USA.

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http://link.springer.com/10.1007/978-1-4939-0709-0_11
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http://dx.doi.org/10.1007/978-1-4939-0709-0_11DOI Listing
May 2015

Integrative clinical transcriptomics analyses for new therapeutic intervention strategies: a psoriasis case study.

Drug Discov Today 2014 Sep 21;19(9):1364-71. Epub 2014 Mar 21.

Computational Biology, Quantitative Sciences, GlaxoSmithKline R&D, RTP, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2014.03.015DOI Listing
September 2014

Modulating the human gut microbiome as an emerging therapeutic paradigm.

Sci Prog 2013 ;96(Pt 3):224-36

Computational Biology, GlaxoSmithKline, Research Triangle Park, NC 27709, USA.

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http://search.proquest.com/openview/8c92587447b0cf2001e54303
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http://dx.doi.org/10.3184/003685013x13691404141587DOI Listing
December 2013

Gastrointestinal weight-loss surgery: glimpses at the molecular level.

Drug Discov Today 2013 Jul 21;18(13-14):625-36. Epub 2012 Dec 21.

Computational Biology, Quantitative Sciences, GlaxoSmithKline, Research Triangle Park, NC, USA.

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http://dx.doi.org/10.1016/j.drudis.2012.12.006DOI Listing
July 2013

Applications of Connectivity Map in drug discovery and development.

Drug Discov Today 2012 Dec 5;17(23-24):1289-98. Epub 2012 Aug 5.

Computational Biology, GlaxoSmithKline, Research Triangle Park, NC 27709, USA.

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http://dx.doi.org/10.1016/j.drudis.2012.07.017DOI Listing
December 2012

The role of translational bioinformatics in drug discovery.

Drug Discov Today 2011 May 21;16(9-10):426-34. Epub 2011 Mar 21.

GlaxoSmithKline, Computational Biology, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, UK.

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http://dx.doi.org/10.1016/j.drudis.2011.03.002DOI Listing
May 2011

Computational biology approaches for selecting host-pathogen drug targets.

Drug Discov Today 2011 Mar 28;16(5-6):229-36. Epub 2011 Jan 28.

Computational Biology, GlaxoSmithKline, 1250 South Collegeville Road, UP1345, PO Box 5089, Collegeville, PA 19426-0989, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S13596446110002
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http://dx.doi.org/10.1016/j.drudis.2011.01.008DOI Listing
March 2011

ERRgamma regulates cardiac, gastric, and renal potassium homeostasis.

Mol Endocrinol 2010 Feb 4;24(2):299-309. Epub 2009 Dec 4.

Gene Expression Laboratory and the Howard Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, California 92037, USA.

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http://dx.doi.org/10.1210/me.2009-0114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817599PMC
February 2010

Understanding biology through bioinformatics.

Authors:
Deepak K Rajpal

Int J Toxicol 2005 May-Jun;24(3):147-52

GlaxoSmithKline, Research Triangle Park, North Carolina 27709-3398, USA.

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http://dx.doi.org/10.1080/10915810590948325DOI Listing
September 2005