Publications by authors named "Debraj Sen"

29 Publications

  • Page 1 of 1

An autopsy series of an oft-missed ante-mortem diagnosis: hemophagocytic lymphohistiocytosis.

Autops Case Rep 2021 Apr 15;11:e2021243. Epub 2021 Apr 15.

Armed Forces Medical College and Command Hospital (Southern Command), Department of Radiodiagnosis and Imaging, Pune, India.

Hemophagocytic lymphohistiocytosis (HLH) is a rare and potentially fatal syndrome resulting from a hyperactivated immune system. Diverse patient profiles and clinical presentations often result in misdiagnosis. This article describes the varied clinical presentations and autopsy findings in three patients with this entity. The etiopathogenesis of HLH, its disparate and confounding clinical features, the diagnostic criteria, and management principles are also briefly reviewed.
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http://dx.doi.org/10.4322/acr.2021.243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8087375PMC
April 2021

Uncommon affliction of a common disease - primary tuberculosis of thyroid gland.

Indian J Pathol Microbiol 2020 Jan-Mar;63(1):83-85

Department of Radiodiagnosis and Imaging, Command Hospital, Pune, Maharashtra, India.

Tuberculosis (TB) continues to be a major public health problem in India. With an annual incidence rate of 2.8 million new cases, India accounts for a quarter of the global TB burden. Primary thyroid TB still remains a rare entity even in this era of global TB pandemic. Here we discuss a case of primary thyroid TB in a 22-year-old immunocompetent male patient presenting with a thyroid swelling followed by non-healing sinus tract after fine-needle aspiration cytology (FNAC) procedure. TB is a known common cause for development of chronic sinuses and ulcers. However, the primary involvement of thyroid gland along with formation of non-healing sinus tract post FNAC make it a most unusual case posing a diagnostic challenge to the unsuspecting physician.
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http://dx.doi.org/10.4103/IJPM.IJPM_719_18DOI Listing
October 2020

Pigmented villonodular synovitis in a child: A missed diagnosis.

Med J Armed Forces India 2019 Oct 16;75(4):467-471. Epub 2017 Dec 16.

Graded Specialist (Orthopaedics), Military Hospital Jodhpur, Rajasthan, India.

Paediatric joint pain and swelling is a frequent presentation. The clinical profile and relevant laboratory investigations often lead to the correct diagnosis; however some patients present a diagnostic conundrum. Pigmented villonodular synovitis (PVNS) is a rare entity that may afflict children and be easily missed.
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http://dx.doi.org/10.1016/j.mjafi.2017.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838497PMC
October 2019

Kimura disease with nephrotic syndrome in a child- A rare association.

Indian J Pathol Microbiol 2019 Jul-Sep;62(3):437-440

Department of Radiodiagnosis and Imaging, Command Hospital, Pune, Maharashtra, India.

Lymphadenopathy along with various systemic manifestations is commonly encountered in pediatric patients, tuberculosis being the commonest etiology. Occasional patients may present a diagnostic conundrum. Here, the authors report an unusual manifestation of Kimura disease (KD) presenting as nephrotic syndrome associated with mesenteric lymphadenitis in an 11-year-old male child. KD is a chronic inflammatory disorder of unknown etiology. It typically affects young adult males in the age range of 27-40 years and usually presents as painless itchy nodular masses in the head and neck region. The involvement of mesenteric lymph nodes along with a very young age of presentation makes it a rare case, posing a diagnostic challenge for the unsuspecting physician.
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http://dx.doi.org/10.4103/IJPM.IJPM_517_18DOI Listing
December 2019

Artificial intelligence and the radiologist: the future in the Armed Forces Medical Services.

BMJ Mil Health 2020 Aug 31;166(4):254-256. Epub 2019 Jan 31.

Department of Radiodiagnosis, Command Hospital (SC), Pune, India.

Artificial intelligence (AI) involves computational networks (neural networks) that simulate human intelligence. The incorporation of AI in radiology will help in dealing with the tedious, repetitive, time-consuming job of detecting relevant findings in diagnostic imaging and segmenting the detected images into smaller data. It would also help in identifying details that are oblivious to the human eye. AI will have an immense impact in populations with deficiency of radiologists and in screening programmes. By correlating imaging data from millions of patients and their clinico-demographic-therapy-morbidity-mortality profiles, AI could lead to identification of new imaging biomarkers. This would change therapy and direct new research. However, issues of standardisation, transparency, ethics, regulations, training, accreditation and safety are the challenges ahead. The Armed Forces Medical Services has widely dispersed units, medical echelons and roles ranging from small field units to large static tertiary care centres. They can incorporate AI-enabled radiological services to subserve small remotely located hospitals and detachments without posted radiologists and ease the load of radiologists in larger hospitals. Early widespread incorporation of information technology and enabled services in our hospitals, adequate funding, regular upgradation of software and hardware, dedicated trained manpower to manage the information technology services and train staff, and cyber security are issues that need to be addressed.
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http://dx.doi.org/10.1136/jramc-2018-001055DOI Listing
August 2020

Giant omental lipoma in an elderly female patient.

Med J Armed Forces India 2018 Oct 17;74(4):377-379. Epub 2017 Jul 17.

Classified Specialist (Pathology), Military Hospital Thiruvananthapuram, India.

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http://dx.doi.org/10.1016/j.mjafi.2017.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224640PMC
October 2018

Taming Alzheimer's disease: New perspectives, newer horizons.

Iran J Neurol 2017 Jul;16(3):146-155

Department of Radiology, Military Hospital, Thiruvananthapuram, India.

Alzheimer's disease (AD) is the leading cause of dementia. However, current therapies do not prevent progression of the disease. New research into the pathogenesis of the disease has brought about a greater understanding of the "amyloid cascade" and associated receptor abnormalities, the role of genetic factors, and revealed that the disease process commences 10 to 20 years prior to the appearance of clinical signs. This greater understanding of the disease has prompted development of novel disease-modifying therapies (DMTs) which may prevent onset or delay progression of the disease. Using genetic biomarkers like apolipoprotein E (ApoE) ε4, biochemical biomarkers like cerebrospinal fluid (CSF) amyloid and tau proteins, and imaging biomarkers like magnetic resonance imaging (MRI) and positron emission tomography (PET), it is now possible to detect preclinical AD and also monitor its progression in asymptomatic people. These biomarkers can be used in the selection of high-risk populations for clinical trials and also to monitor the efficacy and side-effects of DMT. To validate and standardize these biomarkers and select the most reliable, repeatable, easily available, cost-effective and complementary options is the challenge ahead.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673987PMC
July 2017

The imploding antrum: An unusual case of nontraumatic painless enophthalmos.

Indian J Ophthalmol 2016 Oct;64(10):786-788

Department of Radiology, Nijjer Scan and Diagnostic Centre, Amritsar, Punjab, India.

The imploding antrum or silent sinus syndrome is a rare phenomenon that presents with spontaneous painless enophthalmos and hypoglobus. It occurs due to ipsilateral maxillary antral atelectasis secondary to asymptomatic obstructive chronic sinus mucosal disease. Ophthalmologists, otorhinolaryngologists, and radiologists must be aware of this entity. This article illustrates the typical presentation in a 17-year-old male with unilateral ptosis and a deep superior sulcus, and characteristic imaging findings of ipsilateral increased orbital volume and depression of the orbital floor, maxillary sinus opacification and atelectasis with retraction of the posterolateral and medial walls, lateralization of the uncinate process, and obstruction of the ostiomeatal unit. This is probably the first time that the syndrome is being reported in such a young person. The pathogenesis, differential diagnosis, and treatment modalities of this entity are also reviewed.
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http://dx.doi.org/10.4103/0301-4738.195015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168927PMC
October 2016

The "sausage" abscess: abscess of the liagamentum teres hepatis.

BJR Case Rep 2016 2;2(4):20150139. Epub 2016 Nov 2.

Department of Surgery, Army Hospital (R&R), New Delhi, India.

An abscess of the ligamentum teres hepatis is a very rare cause of acute abdomen and can present a diagnostic dilemma. A 40-year-old diabetic male presented with obstructive jaundice and cholangitis. An ill-defined, sausage-shaped, tender parasagittal supraumbilical mass was palpable on the right side. Murphy's sign was negative. Laboratory investigations revealed polymorphonuclear leukocytosis (total leukocyte count 19,000 mm), elevated alkaline phosphatase (400 IU l), conjugated hyperbilirubinaemia (16 mg dl) and elevated blood glucose (240 mg dl). Ultrasonography and MR cholangiopancreatography revealed cholecystolithiasis, obstructive choledocholithiasis, abscess of the ligamentum teres hepatis and left portal thrombosis. Under ultrasound guidance, pus was aspirated from the abscess and the patient was started on broad-spectrum intravenous antibiotics, insulin and low-molecular-weight heparin. He subsequently underwent endoscopic retrograde cholangiopancreatography with sphincterotomy and stone extraction. On the tenth day post admission, he underwent laparoscopic cholecystectomy and excision of the ligament. The patient made an uneventful recovery and was discharged on the seventh post-operative day. On follow-up, the patient remained asymptomatic with normal biochemical parameters. This article highlights the importance of suspecting and identifying an abscess of the ligamentum teres hepatis when a patient with acute abdomen presents with a sausage-shaped right parasagittal mass, especially in the setting of cholangitis, cholecystitis or omphalitis.
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http://dx.doi.org/10.1259/bjrcr.20150139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6243319PMC
November 2016

Duplication of the pituitary gland - plus syndrome.

Indian J Radiol Imaging 2016 Jan-Mar;26(1):126-30

Department of Radiodiagnosis, Nijjer Scan and Diagnostic Centre, Amritsar, India.

Duplication of the pituitary gland (DPG) is a very rare developmental anomaly that is often associated with other anomalies - the DPG-plus syndrome and occurs due to splitting of the rostral notochord and prechordal plate during blastogenesis. DPG with the constellation of associated anomalies as in our patient has not been reported previously. This article illustrates the importance of imaging the brain in all patients with obvious midline facial anomalies and the complementary role of MRI and CT in such cases.
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http://dx.doi.org/10.4103/0971-3026.178361DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4813062PMC
April 2016

Is non-invasive diagnosis of esophageal varices in patients with compensated hepatic cirrhosis possible by duplex Doppler ultrasonography?

Indian J Gastroenterol 2016 Jan 29;35(1):60-6. Epub 2016 Feb 29.

92 Base Hospital, c/o 56 APO, Srinagar, India.

Background And Aim: Esophageal varices are present in 30% to 40% of patients in compensated cirrhosis (Child-Pugh class A) and in 60% to 85% of patients in decompensated cirrhosis (Child-Pugh classes B and C). It is important to identify patients with compensated cirrhosis at risk for esophageal varix development. We evaluated the accuracy of a duplex Doppler ultrasonographic index for predicting the presence or absence of esophageal varices in patients with compensated hepatic cirrhosis (Child-Pugh class A) by using endoscopy as the reference standard.

Methods: Fifty-six enrolled patients underwent duplex Doppler ultrasonography followed by screening endoscopy. Mean portal vein velocity (PVV), splenic index (SI), splenoportal index (SPI), hepatic and splenic arterial resistive, and pulsatility indices (hepatic artery resistive index [HARI], hepatic artery pulsatility index [HAPI], splenic artery resistive index [SARI], splenic artery pulsatility index [SAPI]) were recorded. Univariate logistic regression analysis was followed by receiver operating characteristic (ROC) curve construction for the indices that were significant.

Results: The indices HARI, HAPI, SARI, SAPI were not helpful (p > 0.05). Mean PVV, SI, and SPI were all predictive of the presence of esophageal varices (p < 0.05) and SPI was found to be the most accurate parameter. Of the various cut-off levels of SPI evaluated, a cut-off value of SPI at 5.0, offered the highest diagnostic accuracy (88%). For the 28 patients with SPI <5.0, the absence of esophageal varices in 27 of them could be correctly diagnosed using only SPI without invasive screening endoscopy, with high negative predictive value (96%) and sensitivity (96%). Of the remaining 28 patients with SPI ≥5.0, presence of esophageal varices could be similarly correctly diagnosed in 22 of them by using SPI without screening endoscopy, with high positive predictive value (79%) and specificity (82%).

Conclusion: The SPI was accurate in predicting the presence or absence of esophageal varices in patients with compensated cirrhosis.
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http://dx.doi.org/10.1007/s12664-016-0630-7DOI Listing
January 2016

Ultrasonography and magnetic resonance imaging of ulnar nerve abscess in leprosy.

Med J Armed Forces India 2016 Jan 20;72(1):78-81. Epub 2013 Nov 20.

Resident (Radiodiagnosis), Command Hospital (Central Command), Lucknow, India.

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http://dx.doi.org/10.1016/j.mjafi.2013.09.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4723689PMC
January 2016

Hepatic cystic mesenchymal hamartoma.

Med J Armed Forces India 2015 Dec 6;71(Suppl 2):S574-7. Epub 2014 Nov 6.

Graded Specialist (Radiodiagnosis), 150 General Hospital, C/O 56 APO, India.

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http://dx.doi.org/10.1016/j.mjafi.2014.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705192PMC
December 2015

A rare constellation of imaging findings in Wolman disease.

Med J Armed Forces India 2015 Dec 26;71(Suppl 2):S448-51. Epub 2014 Apr 26.

Resident (Radiodiagnosis), Command Hospital (Central Command), Lucknow 226002, India.

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http://dx.doi.org/10.1016/j.mjafi.2014.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705180PMC
December 2015

Intraosseous pneumatocyst of the cervical vertebra.

Med J Armed Forces India 2015 Oct 20;71(4):380-3. Epub 2013 Nov 20.

Resident (Radiodiagnosis), Command Hospital (CC), Lucknow, India.

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http://dx.doi.org/10.1016/j.mjafi.2013.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646900PMC
October 2015

Vertebral intraosseous lipoma.

Med J Armed Forces India 2015 Jul 2;71(3):293-6. Epub 2013 Aug 2.

Resident (Radiodiagnosis), Command Hospital (Central Command), Lucknow, India.

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http://dx.doi.org/10.1016/j.mjafi.2013.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534534PMC
July 2015

Giant intra-articular extrasynovial osteochondroma of the Hoffa's fat pad.

Med J Armed Forces India 2015 Jul 23;71(Suppl 1):S8-S11. Epub 2013 Feb 23.

Graded Specialist (Pathology), Command Hospital (CC), Lucknow, UP, India.

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http://dx.doi.org/10.1016/j.mjafi.2012.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529516PMC
July 2015

Emergency surgical management of double penile fracture at a peripheral hospital.

Med J Armed Forces India 2015 Jul 10;71(Suppl 1):S46-8. Epub 2013 May 10.

Graded Specialist (Radiodiagnosis), Command Hospital (Central Command), Lucknow 226002, India.

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http://dx.doi.org/10.1016/j.mjafi.2012.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529512PMC
July 2015

A rare case of chronic idiopathic spinal epidural haematoma.

Med J Armed Forces India 2015 Jul 29;71(Suppl 1):S32-5. Epub 2012 Dec 29.

Resident (Radiodiagnosis), Command Hospital (CC), Lucknow 226002, India.

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http://dx.doi.org/10.1016/j.mjafi.2012.10.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4529506PMC
July 2015

MRI and MR tractography in bilateral hypertrophic olivary degeneration.

Indian J Radiol Imaging 2014 Oct;24(4):401-5

Department of Radiodiagnosis, Military Hospital, Jhansi, Uttar Pradesh, India.

Hypertrophic olivary degeneration is a trans-synaptic neuronal degeneration associated with hypertrophy of the inferior olivary nucleus due to a lesion in the triangle of Guillain-Mollaret. Familiarity with this entity on magnetic resonance imaging (MRI) is essential to avoid other erroneous ominous diagnoses. We present a case of bilateral hypertrophic olivary degeneration and discuss the etiopathogenesis and MRI findings in this entity. The contributory role of MR tractography in the diagnosis is also highlighted.
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http://dx.doi.org/10.4103/0971-3026.143902DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247509PMC
October 2014

The "heart appearance" sign in bilateral pontine infarction.

J Stroke Cerebrovasc Dis 2015 Jan 24;24(1):e21-4. Epub 2014 Oct 24.

301 Field Hospital, India.

Background: Although rarely seen, bilateral anteromedial infarction of the pons demonstrates the characteristic "heart appearance" sign on magnetic resonance imaging (MRI). This sign has hitherto been described in only 2 patients before this article. This typical pattern can be attributed to atherosclerotic or thrombotic involvement of bilateral paramedian and short circumferential pontine arteries supplying the anteromedial pons.

Methods And Results: A 60-year-old man, a known patient of primary hypertension and diabetes mellitus, presented with a posterior circulation stroke. Urgent computerized tomography and MRI revealed a "heart-shaped" area of acute infarction in the anteromedian mid-pons. A few scattered infarcts were also noted in the posterior and inferior part of the right cerebellar hemisphere. The basilar artery appeared normal with preserved flow void on MRI, and there were no signs of hemorrhage. These findings were consistent with acute nonhemorrhagic infarcts involving bilateral paramedian and short circumferential pontine arteries and the right posterior inferior cerebellar artery. A repeat MRI performed after a week disclosed hemorrhagic transformation and enhancement of the pontine infarction. The basilar artery appeared normal on magnetic resonance angiography.

Conclusions: Recognizing the "heart appearance" sign in a stroke-like episode may be helpful in differentiating bilateral anteromedial pontine infarction from other pathologic processes involving the pons.
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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2014.08.009DOI Listing
January 2015

A rare occurrence of hepatic portal venous gas in emphysematous pyelonephritis.

Indian J Urol 2014 Jan;30(1):108-9

Department of Urology, Command Hospital (Central Command), Lucknow, Uttar Pradesh, India.

Hepatic portal venous gas (HPVG) is an uncommon radiological sign and often portends significant underlying abdominal disease. A number of conditions may produce this sign and identifying the underlying etiology is essential for management. The advent of ultrasonography-color Doppler imaging and computerized tomography has led to more frequent recognition of this condition. This article describes the very rare association of HPVG in a patient with emphysematous pyelonephritis.
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http://dx.doi.org/10.4103/0970-1591.124218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3897040PMC
January 2014

Microprolactinoma with visual field defect: An unsuspected etiology.

Indian J Endocrinol Metab 2013 Oct;17(Suppl 1):S122-4

Department of Endocrinology, Command Hospital, Central Command, Lucknow, Uttar Pradesh, India.

Microprolactinomas present usually with menstrual disturbance and galactorrhoea. The presence of visual field defects is not expected in these patients as the tumor does not involve structures outside the sella. Visual field defects in a case of microprolactinoma confuse the clinician and warrant extensive search for an alternate etiology. We present a young lady with microprolactinoma and visual field defects. Etiological work-up revealed a diagnosis of idiopathic intracranial hypertension (IIH) associated with microprolactinoma. Treatment with Acetazolamide and Cabergoline completely resolved the clinical symptoms and visual defects. The unusual occurrence of IIH in a case of microprolactinoma as the cause of visual field defect is highlighted in our case report.
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http://dx.doi.org/10.4103/2230-8210.119526DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830275PMC
October 2013

Coping in a calamity: Radiology during the cloudburst at Leh.

Authors:
Debraj Sen

Indian J Radiol Imaging 2013 Jan;23(1):106-9

Department of Radiodiagnosis, Asst Prof. (Radiodiagnosis), Command Hospital (CC), Lucknow, Uttar Pradesh, India.

The service hospital at Leh is a multispeciality hospital situated at an altitude of 11000 feet above mean sea level. On the nights of 4 and 5 Aug 2010, Leh was struck by a cloudburst leading to mudslides and consequently extensive damage to life and property. Being the only functional hospital, over a period of about 48 hours, 331 casualties were received. 549 casualties were received over the week with 108 admissions, 16 major surgeries and 138 minor surgeries. 178 radiographs, 17 CT scans and 09 ultrasound-colour Doppler examinations were performed on an urgent basis over 48 hours apart from the routine radiological investigations. Apart from chronicling the event, we hope that sharing the unique experience of the Radiology Department in dealing with the large influx of patients would provide an insight into the role of Radiology during the disaster and help in planning and developing management protocols during other calamities.
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http://dx.doi.org/10.4103/0971-3026.113629DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3737608PMC
January 2013

Amenorrhea with myxedema: A hidden clue.

Indian J Endocrinol Metab 2013 Mar;17(2):356-7

Department of Endocrinology, Command Hospital, Lucknow, Uttar Pradesh, India.

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http://dx.doi.org/10.4103/2230-8210.109678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3683226PMC
March 2013

D-dimer in the diagnostic workup of suspected pulmonary thrombo-embolism at high altitude.

Med J Armed Forces India 2012 Apr 21;68(2):142-4. Epub 2012 Apr 21.

Deputy Commandant, AFMSD, Mumbai.

Background: Pulmonary thrombo-embolism (PTE) is relatively common in high altitude areas where radiological diagnostic facilities are usually not available. So this study was undertaken to use the results of D-dimer assay to determine the need for imaging studies in patients suspected of having PTE at high altitude.

Methods: A total of 101 patients at an altitude of > 3,000 m suspected of having PTE were evacuated. D-dimer and imaging studies were carried out to confirm the diagnosis.

Results: A total of 101 patients suspected of having PTE underwent D-dimer level estimation and imaging studies for PTE. Sixty-eight of these had negative findings) on D-dimer assay. All these patients with negative findings on D-dimer assay had negative findings on pulmonary imaging studies also. So this test is very sensitive with very high negative predictive value (NPV). Whereas, 17 out of 33 patients positive for D-dimer, had positive findings on imaging studies, indicating a relatively less specific test.

Conclusion: Clinical assessment in combination with D-dimer assay can be used for timely differentiation of PTE from other conditions such as high altitude pulmonary oedema (HAPO) especially at isolated high altitude areas/military posts, so that patients could be evacuated as early as possible by fastest means to save the precious lives and in hospital settings this test identifies patients to whom anticoagulant therapy should not be given or patients who should not be subjected to invasive imaging tests.
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http://dx.doi.org/10.1016/S0377-1237(12)60022-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862702PMC
April 2012

Acanthosis nigricans associated with transitional cell carcinoma of the urinary bladder.

Indian J Dermatol 2011 Nov;56(6):722-5

Department of Dermatology, Graded Specialist (Derm & Ven), Command Hospital Eastern Command, Kolkata, India .

An elderly man from the region of Ladakh presented with recurrent episodes of lower respiratory tract infection, rapidly progressive Acanthosis nigricans, Acanthosis palmaris and plantar keratoderma. Detailed investigations revealed underlying metastatic transitional cell carcinoma of the bladder. This case is being reported for its rarity in the literature.
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http://dx.doi.org/10.4103/0019-5154.91837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276905PMC
November 2011

Orbital emphysema after sneezing: a case report.

Med J Armed Forces India 2011 Jul 7;67(3):282-4. Epub 2011 Aug 7.

Graded Specialist (Ophthalmology), 153 General Hospital, C/O 56 APO.

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http://dx.doi.org/10.1016/S0377-1237(11)60063-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920822PMC
July 2011

Computed tomographic demonstration of unusual ossification of the falx cerebri: a case report.

Surg Radiol Anat 2009 Mar 2;31(3):211-3. Epub 2008 Sep 2.

Department of Radiodiagnosis and Imaging, Command Hospital (SC), Pune, 411 040, Maharashtra, India.

Bony metaplasia of the falx cerebri is rare in human being. We describe a case of extensive ossification involving anterior half of the falx cerebri in a 47-year-old male. This was detected incidentally during computed tomographic examination of the brain for an unrelated cause. The pattern of ossification as demonstrated in the computed tomography scan comprised of dense cortical bone peripherally with medullary bone in the centre resembling the skull vault.
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http://dx.doi.org/10.1007/s00276-008-0408-4DOI Listing
March 2009
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