Publications by authors named "Debra L Silver"

36Publications

Local gene regulation in radial glia: Lessons from across the nervous system.

Traffic 2020 Oct 14. Epub 2020 Oct 14.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC.

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http://dx.doi.org/10.1111/tra.12769DOI Listing
October 2020

Acute Lengthening of Progenitor Mitosis Influences Progeny Fate during Cortical Development in vivo.

Dev Neurosci 2019 15;41(5-6):300-317. Epub 2020 Jun 15.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, USA,

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http://dx.doi.org/10.1159/000507113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7388066PMC
June 2020

Dosage-dependent requirements of for cortical interneuron generation and survival.

Development 2020 01 13;147(1). Epub 2020 Jan 13.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA

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http://dx.doi.org/10.1242/dev.182295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983725PMC
January 2020

Damage Control in the Developing Brain: Tradeoffs and Consequences.

Trends Neurosci 2019 10 22;42(10):661-663. Epub 2019 Aug 22.

Department of Molecular Genetics and Molecular Biology, Duke University Medical Center, Durham, NC, USA; Department of Cell Biology, Duke University Medical Center, Durham, NC, USA; Department of Neurobiology, Duke University Medical Center, Durham, NC, USA; Duke Institute for Brain Science, Duke University Medical Center, Durham, NC, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tins.2019.08.004DOI Listing
October 2019

Progenitor Hyperpolarization Regulates the Sequential Generation of Neuronal Subtypes in the Developing Neocortex.

Cell 2018 08 26;174(5):1264-1276.e15. Epub 2018 Jul 26.

Department of Basic Neurosciences, University of Geneva, 1 Rue Michel Servet, 1211 Geneva, Switzerland; Department of Neurology, Geneva University Hospital, 4 Rue Gabrielle-Perret-Gentil, 1205 Geneva, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.06.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545245PMC
August 2018

A Fluorescent Cell-Based System for Imaging Zika Virus Infection in Real-Time.

Viruses 2018 02 24;10(2). Epub 2018 Feb 24.

Department of Molecular Genetics & Microbiology, Duke University Medical Center, Durham, NC 27710, USA.

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http://www.mdpi.com/1999-4915/10/2/95
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http://dx.doi.org/10.3390/v10020095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850402PMC
February 2018

Enhancing our brains: Genomic mechanisms underlying cortical evolution.

Semin Cell Dev Biol 2018 04 31;76:23-32. Epub 2017 Aug 31.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA; Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA; Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA; Duke Institute for Brain Sciences, Duke University Medical Center, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.semcdb.2017.08.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832537PMC
April 2018

RNA on the brain: emerging layers of post-transcriptional regulation in cerebral cortex development.

Wiley Interdiscip Rev Dev Biol 2018 01 24;7(1). Epub 2017 Aug 24.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1002/wdev.290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746464PMC
January 2018

Moving messages in the developing brain-emerging roles for mRNA transport and local translation in neural stem cells.

FEBS Lett 2017 06 6;591(11):1526-1539. Epub 2017 Apr 6.

Department of Molecular Genetics and Microbiology, Regeneration Next, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1002/1873-3468.12626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497576PMC
June 2017

Dynamic mRNA Transport and Local Translation in Radial Glial Progenitors of the Developing Brain.

Curr Biol 2016 12 1;26(24):3383-3392. Epub 2016 Dec 1.

Department of Molecular Genetics and Microbiology, Research Drive, Duke University Medical Center, Durham, NC 27710, USA; Department of Cell Biology, Research Drive, Duke University Medical Center, Durham, NC 27710, USA; Department of Neurobiology, Research Drive, Duke University Medical Center, Durham, NC 27710, USA; Duke Institute for Brain Sciences, Research Drive, Duke University Medical Center, Durham, NC 27710, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2016.10.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5203927PMC
December 2016

Mouse models of Casc3 reveal developmental functions distinct from other components of the exon junction complex.

RNA 2017 01 25;23(1):23-31. Epub 2016 Oct 25.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1261/rna.058826.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159646PMC
January 2017

Haploinsufficiency for Core Exon Junction Complex Components Disrupts Embryonic Neurogenesis and Causes p53-Mediated Microcephaly.

PLoS Genet 2016 09 12;12(9):e1006282. Epub 2016 Sep 12.

Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, North Carolina, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019403PMC
September 2016

Astrocytes Assemble Thalamocortical Synapses by Bridging NRX1α and NL1 via Hevin.

Cell 2016 Jan;164(1-2):183-196

Department of Cell Biology, Duke University Medical Center, Durham, NC 27710; Department of Neurobiology, Duke University Medical Center, Durham, NC 27710; Duke Institute for Brain Sciences (DIBS), Durham, NC 27710. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.11.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715262PMC
January 2016

Prolonged Mitosis of Neural Progenitors Alters Cell Fate in the Developing Brain.

Neuron 2016 Jan;89(1):83-99

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA; Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA; Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA; Duke Institute for Brain Sciences, Duke University Medical Center, Durham, NC 27710, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08966273150107
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http://dx.doi.org/10.1016/j.neuron.2015.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706996PMC
January 2016

Genomic divergence and brain evolution: How regulatory DNA influences development of the cerebral cortex.

Authors:
Debra L Silver

Bioessays 2016 Feb 7;38(2):162-71. Epub 2015 Dec 7.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1002/bies.201500108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4718859PMC
February 2016

Post-transcriptional regulation in corticogenesis: how RNA-binding proteins help build the brain.

Wiley Interdiscip Rev RNA 2015 Sep-Oct;6(5):501-15. Epub 2015 Jun 18.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1002/wrna.1289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624281PMC
May 2016

Rbm8a haploinsufficiency disrupts embryonic cortical development resulting in microcephaly.

J Neurosci 2015 May;35(18):7003-18

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina 27710, Department of Cell Biology, Department of Neurobiology, and Duke Institute for Brain Sciences, Duke University Medical Center, Durham, North Carolina 27710

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http://dx.doi.org/10.1523/JNEUROSCI.0018-15.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420776PMC
May 2015

Human-chimpanzee differences in a FZD8 enhancer alter cell-cycle dynamics in the developing neocortex.

Curr Biol 2015 Mar 19;25(6):772-779. Epub 2015 Feb 19.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA; Department of Cell Biology, Duke University Medical Center, Durham, NC 27710, USA; Department of Neurobiology, Duke University Medical Center, Durham, NC 27710, USA; Duke Institute for Brain Sciences, Durham, NC 27710 USA. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2015.01.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4366288PMC
March 2015

Live imaging of mitosis in the developing mouse embryonic cortex.

J Vis Exp 2014 Jun 4(88). Epub 2014 Jun 4.

Department of Molecular Genetics and Microbiology, Duke University Medical Center; Departments of Neurobiology and Cell Biology, Duke Institute for Brain Sciences, Duke University Medical Center;

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http://dx.doi.org/10.3791/51298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4186649PMC
June 2014

Generation of a Magoh conditional allele in mice.

Genesis 2014 Aug 9;52(8):752-8. Epub 2014 May 9.

Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina.

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http://dx.doi.org/10.1002/dvg.22788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111959PMC
August 2014

Genetic interaction screens identify a role for hedgehog signaling in Drosophila border cell migration.

Dev Dyn 2013 May 8;242(5):414-31. Epub 2013 Feb 8.

Division of Cell Biology and Biophysics, School of Biological Sciences, University of Missouri-Kansas City, Kansas City, Missouri 64110, USA.

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http://dx.doi.org/10.1002/dvdy.23926DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3721345PMC
May 2013

The EJC component Magoh regulates proliferation and expansion of neural crest-derived melanocytes.

Dev Biol 2013 Mar 18;375(2):172-81. Epub 2013 Jan 18.

Genetic Disease Research Branch, National Human Genome Research Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ydbio.2013.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3710740PMC
March 2013

The exon junction complex component Magoh controls brain size by regulating neural stem cell division.

Nat Neurosci 2010 May 4;13(5):551-8. Epub 2010 Apr 4.

Genetic Disease Research Branch, National Human Genome Research Institute (NHGRI), National Institutes of Health (NIH), Bethesda, Maryland, USA.

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http://dx.doi.org/10.1038/nn.2527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860667PMC
May 2010

The secreted metalloprotease ADAMTS20 is required for melanoblast survival.

PLoS Genet 2008 Feb 29;4(2):e1000003. Epub 2008 Feb 29.

Genetic Disease Research Branch, National Human Genome Research Institute, Bethesda, Maryland, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1000003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2265537PMC
February 2008

A sensitized mutagenesis screen identifies Gli3 as a modifier of Sox10 neurocristopathy.

Hum Mol Genet 2008 Jul 7;17(14):2118-31. Epub 2008 Apr 7.

Genetic Disease Research Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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https://academic.oup.com/hmg/article-lookup/doi/10.1093/hmg/
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http://dx.doi.org/10.1093/hmg/ddn110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902284PMC
July 2008

The genetic regulation of pigment cell development.

Adv Exp Med Biol 2006 ;589:155-69

Genetic Diseases Branch, NHGRI, NIH, Room 4A51, Bldg. 49, 49 Convent Drive, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1007/978-0-387-46954-6_9DOI Listing
November 2006

Requirement for JAK/STAT signaling throughout border cell migration in Drosophila.

Development 2005 Aug 6;132(15):3483-92. Epub 2005 Jul 6.

Department of Biological Chemistry, Johns Hopkins School of Medicine, 725 North Wolfe Street, Baltimore, MD 212052, USA.

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http://dx.doi.org/10.1242/dev.01910DOI Listing
August 2005

Activated signal transducer and activator of transcription (STAT) 3: localization in focal adhesions and function in ovarian cancer cell motility.

Cancer Res 2004 May;64(10):3550-8

Department of Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, Maryland 21205, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-03-3959DOI Listing
May 2004

A new trick for Cyclin-Cdk: activation of STAT.

Dev Cell 2003 Feb;4(2):148-9

Department of Biological Chemistry, Johns Hopkins School of Medicine, 725 Wolfe Street, Baltimore, MD 21205, USA.

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http://dx.doi.org/10.1016/s1534-5807(03)00028-5DOI Listing
February 2003