Debra Cromley

Debra Cromley

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Debra Cromley

Debra Cromley

Publications by authors named "Debra Cromley"

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11Publications

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A novel approach to measuring macrophage-specific reverse cholesterol transport in vivo in humans.

Authors:
Marina Cuchel Anna C Raper Donna M Conlon Daniel A Pryma Richard H Freifelder Rahul Poria Debra Cromley Xiaoyu Li Richard L Dunbar Benjamin French Liming Qu William Farver Ching-Chiang Su Sissel Lund-Katz Amanda Baer Giacomo Ruotolo Peter Akerblad Carol S Ryan Lan Xiao Todd G Kirchgessner John S Millar Jeffrey T Billheimer Daniel J Rader

J Lipid Res 2017 04 6;58(4):752-762. Epub 2017 Feb 6.

Division of Translational Medicine and Human Genetics, Department of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1194/jlr.M075226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392750PMC
April 2017

Design and synthesis of boronic acid inhibitors of endothelial lipase.

Authors:
Daniel P O'Connell Daniel F LeBlanc Debra Cromley Jeffrey Billheimer Daniel J Rader William W Bachovchin

Bioorg Med Chem Lett 2012 Feb 13;22(3):1397-401. Epub 2011 Dec 13.

Tufts University School of Medicine, Department of Biochemistry, 136 Harrison Ave., Boston, MA 02111, United States.

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http://dx.doi.org/10.1016/j.bmcl.2011.12.043DOI Listing
February 2012

Gene therapy in a humanized mouse model of familial hypercholesterolemia leads to marked regression of atherosclerosis.

Authors:
Sadik H Kassim Hui Li Luk H Vandenberghe Christian Hinderer Peter Bell Dawn Marchadier Aisha Wilson Debra Cromley Valeska Redon Hongwei Yu James M Wilson Daniel J Rader

PLoS One 2010 Oct 19;5(10):e13424. Epub 2010 Oct 19.

Gene Therapy Program, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013424PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957433PMC
October 2010

Knockdown of acyl-CoA:diacylglycerol acyltransferase 2 with antisense oligonucleotide reduces VLDL TG and ApoB secretion in mice.

Authors:
Ying Liu John S Millar Debra A Cromley Mark Graham Rosanne Crooke Jeffrey T Billheimer Daniel J Rader

Biochim Biophys Acta 2008 Mar 17;1781(3):97-104. Epub 2008 Jan 17.

Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104-6160, USA.

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http://dx.doi.org/10.1016/j.bbalip.2008.01.001DOI Listing
March 2008

Acyl coenzyme A dependent retinol esterification by acyl coenzyme A: diacylglycerol acyltransferase 1.

Authors:
Michael D Orland Kamran Anwar Debra Cromley Ching-Hsuen Chu Luping Chen Jeffrey T Billheimer M Mahmood Hussain Dong Cheng

Biochim Biophys Acta 2005 Oct 20;1737(1):76-82. Epub 2005 Sep 20.

Department of Obesity and Metabolic Research, Pharmaceutical Research Institute, Bristol-Myers Squibb Company, Princeton, NJ 08543-5400, USA.

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http://dx.doi.org/10.1016/j.bbalip.2005.09.003DOI Listing
October 2005

Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339.

Authors:
John S Millar Debra A Cromley Mary G McCoy Daniel J Rader Jeffrey T Billheimer

J Lipid Res 2005 Sep 1;46(9):2023-8. Epub 2005 Jul 1.

Institute for Translational Medicine and Therapeutics, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1194/jlr.D500019-JLR200DOI Listing
September 2005

Identification of two novel human acyl-CoA wax alcohol acyltransferases: members of the diacylglycerol acyltransferase 2 (DGAT2) gene superfamily.

Authors:
Aaron R Turkish Annette L Henneberry Debra Cromley Mahajabeen Padamsee Peter Oelkers Hisham Bazzi Angela M Christiano Jeffrey T Billheimer Stephen L Sturley

J Biol Chem 2005 Apr 25;280(15):14755-64. Epub 2005 Jan 25.

Department of Pediatrics, Columbia University Medical Center, New York, New York 10032, USA.

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http://dx.doi.org/10.1074/jbc.M500025200DOI Listing
April 2005

Raising HDL cholesterol without inducing hepatic steatosis and hypertriglyceridemia by a selective LXR modulator.

Authors:
Bowman Miao Susan Zondlo Sandy Gibbs Debra Cromley Vinayak P Hosagrahara Todd G Kirchgessner Jeffrey Billheimer Ranjan Mukherjee

J Lipid Res 2004 Aug 16;45(8):1410-7. Epub 2004 May 16.

Cardiovascular Biology, Bristol-Myers Squibb Company, Experimental Station, Wilmington, DE 19880, USA.

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http://dx.doi.org/10.1194/jlr.M300450-JLR200DOI Listing
August 2004

Prospective testing for drug-dependent antibodies reduces the incidence of thrombocytopenia observed with the small molecule glycoprotein IIb/IIIa antagonist roxifiban: implications for the etiology of thrombocytopenia.

Authors:
Dietmar Seiffert Andrew M Stern William Ebling Richard J Rossi Yu Chen Barrett Richard Wynn Gregory F Hollis Bokang He Cathy J Kieras Donna L Pedicord Debra A Cromley Tsushung A Hua Robert B Stein Robert N Daly Anthony Sferruzza Henry J Pieniaszek Jeffrey T Billheimer

Blood 2003 Jan 28;101(1):58-63. Epub 2002 Jun 28.

Bristol-Myers Squibb, Wilmington, DE 19880, USA.

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http://dx.doi.org/10.1182/blood-2002-02-0471DOI Listing
January 2003

Evidence that thrombocytopenia observed in humans treated with orally bioavailable glycoprotein IIb/IIIa antagonists is immune mediated.

Authors:
Jeffrey T Billheimer Ira B Dicker Richard Wynn Jodi D Bradley Debra A Cromley Helen E Godonis Lisa C Grimminger Bokang He Cathy J Kieras Donna L Pedicord Susan M Spitz Beth E Thomas Nina I Zolotarjova Mary A Gorko Gregory F Hollis Robert N Daly Andrew M Stern Dietmar Seiffert

Blood 2002 May;99(10):3540-6

Department of Chemical Enzymology, Bristol-Myers Squibb Pharma Company, Wilmington, DE 19880-0400, USA.

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http://dx.doi.org/10.1182/blood.v99.10.3540DOI Listing
May 2002

The DGA1 gene determines a second triglyceride synthetic pathway in yeast.

Authors:
Peter Oelkers Debra Cromley Mahajabeen Padamsee Jeffrey T Billheimer Stephen L Sturley

J Biol Chem 2002 Mar 18;277(11):8877-81. Epub 2001 Dec 18.

Institute of Human Nutrition and the Department of Pediatrics, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA.

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http://dx.doi.org/10.1074/jbc.M111646200DOI Listing
March 2002