Deborah Smyth

Deborah Smyth

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Deborah Smyth

Publications by authors named "Deborah Smyth"

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Inactivation of the dnaK gene in Clostridium difficile 630 Δerm yields a temperature-sensitive phenotype and increases biofilm-forming ability.

Sci Rep 2017 12 13;7(1):17522. Epub 2017 Dec 13.

Nutrition Innovation Centre for Food and HEalth (NICHE), School of Biomedical Sciences,University of Ulster, Coleraine, Co. Londonderry, N. Ireland, BT52 1SA, UK.

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http://dx.doi.org/10.1038/s41598-017-17583-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727486PMC
December 2017

Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity.

J Autoimmun 2017 Nov 23;84:75-86. Epub 2017 Jul 23.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK; JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust/MRC Building, Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Research Campus, Cambridge, UK. Electronic address:

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http://dx.doi.org/10.1016/j.jaut.2017.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656572PMC
November 2017

Capturing the systemic immune signature of a norovirus infection: an n-of-1 case study within a clinical trial.

Wellcome Open Res 2017 5;2:28. Epub 2017 Oct 5.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Campus,Cambridge, CB2 0XY, UK.

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https://wellcomeopenresearch.org/articles/2-28/v3
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http://dx.doi.org/10.12688/wellcomeopenres.11300.3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5531165PMC
October 2017

Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2.

JCI Insight 2017 Aug 17;2(16). Epub 2017 Aug 17.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Wellcome Trust Centre for Human Genetics, Nuffield Department of Medicine, National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1172/jci.insight.93739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621870PMC
August 2017

Natural Variation in Interleukin-2 Sensitivity Influences Regulatory T-Cell Frequency and Function in Individuals With Long-standing Type 1 Diabetes.

Diabetes 2015 Nov 29;64(11):3891-902. Epub 2015 Jul 29.

Department of Immunobiology, Faculty of Life Sciences & Medicine, King's College London, London, U.K. National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas' National Health Service Foundation Trust and King's College London, London, U.K.

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http://dx.doi.org/10.2337/db15-0516DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975524PMC
November 2015

Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing.

Eur J Immunol 2015 Nov 1;45(11):3200-3. Epub 2015 Oct 1.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge Biomedical Research Campus, Cambridge, UK.

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http://dx.doi.org/10.1002/eji.201545646DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4832369PMC
November 2015

Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping.

PLoS Genet 2015 Jun 24;11(6):e1005272. Epub 2015 Jun 24.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1005272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4481316PMC
June 2015

Widespread seasonal gene expression reveals annual differences in human immunity and physiology.

Nat Commun 2015 May 12;6:7000. Epub 2015 May 12.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1038/ncomms8000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432600PMC
May 2015

IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients.

Diabetologia 2015 Apr 6;58(4):781-90. Epub 2015 Feb 6.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, WT/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0XY, UK,

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http://dx.doi.org/10.1007/s00125-015-3509-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351433PMC
April 2015

Detection and correction of artefacts in estimation of rare copy number variants and analysis of rare deletions in type 1 diabetes.

Hum Mol Genet 2015 Mar 25;24(6):1774-90. Epub 2014 Nov 25.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Cambridge CB2 0XY, UK,

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http://hmg.oxfordjournals.org/content/early/2014/11/25/hmg.d
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http://www.hmg.oxfordjournals.org/cgi/doi/10.1093/hmg/ddu581
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http://dx.doi.org/10.1093/hmg/ddu581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381751PMC
March 2015

A method for gene-based pathway analysis using genomewide association study summary statistics reveals nine new type 1 diabetes associations.

Genet Epidemiol 2014 Dec 4;38(8):661-70. Epub 2014 Nov 4.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK.

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http://dx.doi.org/10.1002/gepi.21853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258092PMC
December 2014

A hybrid qPCR/SNP array approach allows cost efficient assessment of KIR gene copy numbers in large samples.

BMC Genomics 2014 Apr 11;15:274. Epub 2014 Apr 11.

JDRF/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, CB2 0XY, Cambridge, UK.

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http://dx.doi.org/10.1186/1471-2164-15-274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029094PMC
April 2014

Functional IL6R 358Ala allele impairs classical IL-6 receptor signaling and influences risk of diverse inflammatory diseases.

PLoS Genet 2013 Apr 4;9(4):e1003444. Epub 2013 Apr 4.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, NIHR Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1003444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3617094PMC
April 2013

Postthymic expansion in human CD4 naive T cells defined by expression of functional high-affinity IL-2 receptors.

J Immunol 2013 Mar 15;190(6):2554-66. Epub 2013 Feb 15.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge CB2 0XY, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1202914DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3614027PMC
March 2013

Evidence of gene-gene interaction and age-at-diagnosis effects in type 1 diabetes.

Diabetes 2012 Nov 13;61(11):3012-7. Epub 2012 Aug 13.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, Department of Medical Genetics, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.2337/db11-1694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478521PMC
November 2012

Statistical colocalization of monocyte gene expression and genetic risk variants for type 1 diabetes.

Hum Mol Genet 2012 Jun 8;21(12):2815-24. Epub 2012 Mar 8.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, University of Cambridge, Addenbrooke’s Hospital, Cambridge, UK.

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http://dx.doi.org/10.1093/hmg/dds098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3363338PMC
June 2012

FUT2 nonsecretor status links type 1 diabetes susceptibility and resistance to infection.

Diabetes 2011 Nov;60(11):3081-4

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.2337/db11-0638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198057PMC
November 2011

Genetic association analyses of atopic illness and proinflammatory cytokine genes with type 1 diabetes.

Diabetes Metab Res Rev 2011 Nov;27(8):838-43

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge CB2 0XY, UK.

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http://dx.doi.org/10.1002/dmrr.1259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816329PMC
November 2011

Evidence that HLA class I and II associations with type 1 diabetes, autoantibodies to GAD and autoantibodies to IA-2, are distinct.

Diabetes 2011 Oct 10;60(10):2635-44. Epub 2011 Aug 10.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetesand Inflammation Laboratory, Cambridge Institute for Medical Research, Departmentof Medical Genetics, University of Cambridge, Cambridge, U.K.

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http://dx.doi.org/10.2337/db11-0131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178284PMC
October 2011

Genetic analysis of adult-onset autoimmune diabetes.

Diabetes 2011 Oct 26;60(10):2645-53. Epub 2011 Aug 26.

Department of Medical Genetics, Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, U.K.

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http://dx.doi.org/10.2337/db11-0364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178303PMC
October 2011

Genome-wide association analysis of autoantibody positivity in type 1 diabetes cases.

PLoS Genet 2011 Aug 4;7(8):e1002216. Epub 2011 Aug 4.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1002216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150451PMC
August 2011

Inherited variation in vitamin D genes is associated with predisposition to autoimmune disease type 1 diabetes.

Diabetes 2011 May 25;60(5):1624-31. Epub 2011 Mar 25.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.2337/db10-1656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292339PMC
May 2011

An allele of IKZF1 (Ikaros) conferring susceptibility to childhood acute lymphoblastic leukemia protects against type 1 diabetes.

Diabetes 2011 Mar 26;60(3):1041-4. Epub 2011 Jan 26.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://diabetes.diabetesjournals.org/lookup/doi/10.2337/db10
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http://dx.doi.org/10.2337/db10-0446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3046822PMC
March 2011

Reduced expression of IFIH1 is protective for type 1 diabetes.

PLoS One 2010 Sep 9;5(9). Epub 2010 Sep 9.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2936573PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012646PLOS
September 2010

Common genetic determinants of vitamin D insufficiency: a genome-wide association study.

Lancet 2010 Jul 10;376(9736):180-8. Epub 2010 Jun 10.

Division of Cardiology, Department of Medicine, Massachusetts General Hospital, Boston, MA 02114, USA.

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http://dx.doi.org/10.1016/S0140-6736(10)60588-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3086761PMC
July 2010

The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes.

Nat Genet 2010 Jan 6;42(1):68-71. Epub 2009 Dec 6.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.493DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2820243PMC
January 2010

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes.

Nat Genet 2009 Jun 10;41(6):703-7. Epub 2009 May 10.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://www.nature.com/articles/ng.381
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http://dx.doi.org/10.1038/ng.381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889014PMC
June 2009

Statistical independence of the colocalized association signals for type 1 diabetes and RPS26 gene expression on chromosome 12q13.

Biostatistics 2009 Apr 27;10(2):327-34. Epub 2008 Nov 27.

Juveniles Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1093/biostatistics/kxn039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648905PMC
April 2009

Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci.

Nat Genet 2008 Dec 2;40(12):1399-401. Epub 2008 Nov 2.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635556PMC
December 2008

Shared and distinct genetic variants in type 1 diabetes and celiac disease.

N Engl J Med 2008 Dec 10;359(26):2767-77. Epub 2008 Dec 10.

Juvenile Diabetes Research Foundation-Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.

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http://www.nejm.org/doi/abs/10.1056/NEJMoa0807917
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http://dx.doi.org/10.1056/NEJMoa0807917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2840835PMC
December 2008

Creating environment for cancer care.

Health Facil Manage 2008 Nov;21(11):19-30

BSA Life Structures, Indianapolis, USA.

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November 2008

PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes.

Diabetes 2008 Jun 27;57(6):1730-7. Epub 2008 Feb 27.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db07-11
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http://dx.doi.org/10.2337/db07-1131DOI Listing
June 2008

Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A.

Nature 2007 Dec 14;450(7171):887-92. Epub 2007 Nov 14.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute of Medical Research, University of Cambridge, CB2 0XY, UK.

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http://dx.doi.org/10.1038/nature06406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2703779PMC
December 2007

The candidate genes TAF5L, TCF7, PDCD1, IL6 and ICAM1 cannot be excluded from having effects in type 1 diabetes.

BMC Med Genet 2007 Nov 28;8:71. Epub 2007 Nov 28.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://bmcmedgenet.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2350-8-71DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2217539PMC
November 2007

Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes.

Diabetes 2007 Oct 2;56(10):2616-21. Epub 2007 Jul 2.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.2337/db07-0652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493063PMC
October 2007

Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

Nat Genet 2007 Sep 5;39(9):1074-82. Epub 2007 Aug 5.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, UK.

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http://www.nature.com/doifinder/10.1038/ng2102
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http://dx.doi.org/10.1038/ng2102DOI Listing
September 2007

A genome-wide association study of nonsynonymous SNPs identifies a type 1 diabetes locus in the interferon-induced helicase (IFIH1) region.

Nat Genet 2006 Jun 14;38(6):617-9. Epub 2006 May 14.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, UK.

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http://dx.doi.org/10.1038/ng1800DOI Listing
June 2006

No evidence for association of OAS1 with type 1 diabetes in unaffected siblings or type 1 diabetic cases.

Diabetes 2006 May;55(5):1525-8

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2XY, U.K.

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http://dx.doi.org/10.2337/db05-1452DOI Listing
May 2006

Discovery, linkage disequilibrium and association analyses of polymorphisms of the immune complement inhibitor, decay-accelerating factor gene (DAF/CD55) in type 1 diabetes.

BMC Genet 2006 Apr 20;7:22. Epub 2006 Apr 20.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 2XY, UK.

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http://dx.doi.org/10.1186/1471-2156-7-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479364PMC
April 2006

Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases.

BMC Med Genet 2006 Mar 6;7:20. Epub 2006 Mar 6.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Addenbrooke's Hospital, Hills Rd, Cambridge, CB2 2XY, UK.

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http://bmcmedgenet.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2350-7-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1420277PMC
March 2006

Population structure, differential bias and genomic control in a large-scale, case-control association study.

Nat Genet 2005 Nov 9;37(11):1243-6. Epub 2005 Oct 9.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC Building, Cambridge, CB2 2XY, UK.

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http://www.nature.com/articles/ng1653
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http://dx.doi.org/10.1038/ng1653DOI Listing
November 2005

No evidence for association of the TATA-box binding protein glutamine repeat sequence or the flanking chromosome 6q27 region with type 1 diabetes.

Biochem Biophys Res Commun 2005 Jun;331(2):435-41

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Hills Road, Cambridge, UK.

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http://dx.doi.org/10.1016/j.bbrc.2005.03.203DOI Listing
June 2005

Investigating the utility of combining phi29 whole genome amplification and highly multiplexed single nucleotide polymorphism BeadArray genotyping.

BMC Biotechnol 2004 Jul 27;4:15. Epub 2004 Jul 27.

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes, Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Wellcome Trust/MRC Building, Cambridge, CB2 2XY, UK.

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http://dx.doi.org/10.1186/1472-6750-4-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC514612PMC
July 2004

Haplotype tag single nucleotide polymorphism analysis of the human orthologues of the rat type 1 diabetes genes Ian4 (Lyp/Iddm1) and Cblb.

Diabetes 2004 Feb;53(2):505-9

Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke's Hospital, Cambridge, U.K.

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http://dx.doi.org/10.2337/diabetes.53.2.505DOI Listing
February 2004