Deborah Hirtz

Deborah Hirtz

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Deborah Hirtz

Publications by authors named "Deborah Hirtz"

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Sickle Cell Disease and Stroke.

Pediatr Neurol 2019 06 27;95:34-41. Epub 2019 Feb 27.

Developmental Neurosciences Section and Biomedical Research Unit, Clinical and Experimental Sciences, University of Southampton, UCL Great Ormond Street Institute of Child Health, London, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08878994183130
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http://dx.doi.org/10.1016/j.pediatrneurol.2019.02.018DOI Listing
June 2019

Sensitivity and specificity of early screening for autism.

BJPsych Open 2019 May 17;5(3):e41. Epub 2019 May 17.

Director General and Professor, Norwegian Institute of Public Health; and Department of Global Public Health and Primary Care, University of Bergen, Norway.

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http://dx.doi.org/10.1192/bjo.2019.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537444PMC
May 2019

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic drugs I: Treatment of new-onset epilepsy: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Epilepsy Society.

Neurology 2018 07 13;91(2):74-81. Epub 2018 Jun 13.

From the Miller School of Medicine (A.M.K.), University of Miami, FL; Bronson Neuroscience Center (E.A.), Bronson Methodist Hospital, Kalamazoo, MI; Department of Neurology (D.G.), Charleston Area Medical Center, Charleston, WV; Department of Neurology (C.H.), Mount Sinai Beth Israel, New York, NY; Children's Hospital (B.B.), Harvard Medical School, Boston, MA; Epilepsy Center (J.F.B.), Cleveland Clinic Foundation, OH; Department of Neurology (B.A.-K.), Vanderbilt University, Nashville, TN; Department of Neurology (E.B.-D.), Cooper Medical School, Rowan University, Cherry Hill, NJ; AMITA Health Medical Group (E.L.P.), Hoffman Estates, IL; School of Medicine (J.S.), University of California, Los Angeles; School of Medicine (D.H.), University of Vermont, Burlington; Children's Hospital (M.N.), University of California San Diego School of Medicine; School of Pharmacy (B.G.), University of Wisconsin, Madison; School of Medicine (E.F.), Emory University, Atlanta, GA; and Department of Neurology (J.F.), New York University Langone Comprehensive Epilepsy Center, New York.

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http://dx.doi.org/10.1212/WNL.0000000000005755DOI Listing
July 2018

Practice guideline update summary: Efficacy and tolerability of the new antiepileptic drugs II: Treatment-resistant epilepsy: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology and the American Epilepsy Society.

Neurology 2018 07 13;91(2):82-90. Epub 2018 Jun 13.

From Miller School of Medicine (A.M.K.), University of Miami, FL; Bronson Methodist Hospital (E.A.), Kalamazoo, MI; Charleston Area Medical Center (D.G.), Charleston, WV; Mount Sinai Beth Israel (C.H.), New York, NY; Children's Hospital, Harvard Medical School (B.B.), Boston, MA; Cleveland Clinic Foundation (J.F.B.), OH; Department of Neurology (B.-A.K.), School of Medicine, Nashville, TN; Cooper Medical School (E.B.-D.), Rowan University, Cherry Hill, NJ; Alexian Brothers Medical Group (E.L.P.), Hoffman Estates, IL; School of Medicine (J.S.), University of California in Los Angeles; University of Vermont Medical Center (D.H.), Burlington; Children's Hospital (M.N.), University of California San Diego School of Medicine; School of Pharmacy (B.G.), University of Wisconsin, Madison; Emory University School of Medicine (E.F.), Atlanta, GA; and New York University (J.F.), New York.

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http://dx.doi.org/10.1212/WNL.0000000000005756DOI Listing
July 2018

Pretreatment behavior and subsequent medication effects in childhood absence epilepsy.

Neurology 2017 Oct 15;89(16):1698-1706. Epub 2017 Sep 15.

From Montefiore Medical Center (R.C.S., S.S., D.M., E.F.W.), Albert Einstein College of Medicine, Bronx, NY; George Washington University (A.C.), Washington, DC; Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine (P.C., C.L., T.A.G.), OH; The Children's Hospital of Philadelphia (D.D.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia; National Institute of Neurological Disorders and Stroke (D.G.H.); and Henry M. Jackson Foundation for the Advancement of Military Medicine (F.H.), Bethesda, MD.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000004514DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5644466PMC
October 2017

Pretreatment seizure semiology in childhood absence epilepsy.

Neurology 2017 Aug 19;89(7):673-679. Epub 2017 Jul 19.

From the Children's Hospital of Philadelphia (S.K.K., D.D.), Perelman School of Medicine, University of Pennsylvania; Montefiore Medical Center (S.S., S.L.M.), Albert Einstein College of Medicine, Bronx, NY; Children's National Health System (A.C., J.C., F.H.), Washington, DC; National Institute of Neurological Disorders and Stroke (D.G.H.), Bethesda, MD; Comprehensive Epilepsy Center (C.L., P.C., T.A.G.), Division of Neurology, Cincinnati Children's Hospital Medical Center, OH; and Baylor College of Medicine (E.M.M.), Houston, TX.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000004226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5562968PMC
August 2017

Treatment of Subclinical Hypothyroidism or Hypothyroxinemia in Pregnancy.

N Engl J Med 2017 03;376(9):815-825

From the University of Texas Southwestern Medical Center, Dallas (B.M.C.), the University of Texas Medical Branch, Galveston (G.S.), and the University of Texas Health Science Center at Houston, McGovern Medical School-Children's Memorial Hermann Hospital, Houston (B.S.) - all in Texas; George Washington University Biostatistics Center, Washington, DC (E.A.T.); Northwestern University, Chicago (A.M.P.); the University of Utah Health Sciences Center, Salt Lake City (M.W.V.); Wayne State University, Detroit (Y.S.); the National Institute of Neurological Disorders and Stroke (D.G.H.) and the Eunice Kennedy Shriver National Institute of Child Health and Human Development (U.M.R.), Bethesda, MD; Columbia University, New York (R.J.W.); the University of North Carolina at Chapel Hill, Chapel Hill (J.M.T.); the University of Alabama at Birmingham, Birmingham (A.T.N.T.); Brown University, Providence, RI (D.J.R.); Ohio State University, Columbus (J.D.I.), and MetroHealth Medical Center-Case Western Reserve University, Cleveland (B.M.M.) - both in Ohio; Oregon Health and Science University, Portland (J.T.); University of Pittsburgh, Pittsburgh (S.N.C.); and the Medical University of South Carolina, Charleston (J.P.V.).

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http://dx.doi.org/10.1056/NEJMoa1606205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605129PMC
March 2017

Targeting Environmental Neurodevelopmental Risks to Protect Children.

Pediatrics 2017 02;139(2)

Faculty of Health Sciences, Simon Fraser University, Vancouver, British Columbia, Canada.

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http://pediatrics.aappublications.org/lookup/doi/10.1542/ped
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http://dx.doi.org/10.1542/peds.2016-2245DOI Listing
February 2017

Maternal Immunoreactivity to Herpes Simplex Virus 2 and Risk of Autism Spectrum Disorder in Male Offspring.

mSphere 2017 Jan-Feb;2(1). Epub 2017 Feb 22.

Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York, USA; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA.

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http://msphere.asm.org/lookup/doi/10.1128/mSphere.00016-17
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http://dx.doi.org/10.1128/mSphere.00016-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5322345PMC
February 2017

Second monotherapy in childhood absence epilepsy.

Neurology 2017 Jan 16;88(2):182-190. Epub 2016 Dec 16.

From Children's National Health System (A.C.), Washington, DC; Montefiore Medical Center (S.S., D.M.), Albert Einstein College of Medicine, New York, NY; Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine (R.A., P.O.C., T.A.G.), OH; The Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania (P.C.A., D.D.); and National Institute of Neurological Disorders and Stroke (D.G.H.), Bethesda, MD.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000003480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224720PMC
January 2017

Cerebellar Hemorrhage in the Premature Infant-Time for a Balanced Approach.

J Pediatr 2016 11 12;178:9-10. Epub 2016 Aug 12.

Departments of Pediatrics and Neurology Yale School of Medicine New Haven, Connecticut.

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http://dx.doi.org/10.1016/j.jpeds.2016.07.036DOI Listing
November 2016

Report of a workshop on research gaps in the treatment of cerebral palsy.

Neurology 2016 Sep 24;87(12):1293-8. Epub 2016 Aug 24.

From the Office of the Clinical Director (C.L.) and Office of Clinical Research (D.H.), National Institute of Neurological Disorders and Stroke, NIH, Bethesda; Functional and Applied Biomechanics Section (D.D.), Clinical Center, NIH, Bethesda, MD; Cerebral Palsy Research Network (P.G.), Woodinville, WA; and Departments of Neurology, Neuroscience, and Pediatrics (J.W.M.), University of Rochester, NY.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035982PMC
http://dx.doi.org/10.1212/WNL.0000000000003116DOI Listing
September 2016

What we learned about the role of antenatal magnesium sulfate for the prevention of cerebral palsy.

Semin Perinatol 2016 08 23;40(5):303-6. Epub 2016 Apr 23.

Department of Neurological Sciences and Pediatrics, University of Vermont HSRF 426, 149 Beaumont Avenue, Burlington, VT 05405.

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http://dx.doi.org/10.1053/j.semperi.2016.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314306PMC
August 2016

Girls and Boys Born before 28 Weeks Gestation: Risks of Cognitive, Behavioral, and Neurologic Outcomes at Age 10 Years.

J Pediatr 2016 Jun 19;173:69-75.e1. Epub 2016 Mar 19.

Department of Neurology, Harvard Medical School, Boston, MA; Department of Neurology, Neuroepidemiology Unit, Boston Children's Hospital, Boston, MA.

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http://dx.doi.org/10.1016/j.jpeds.2016.02.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4884461PMC
June 2016

Long-term outcomes of generalized tonic-clonic seizures in a childhood absence epilepsy trial.

Neurology 2015 Sep 26;85(13):1108-14. Epub 2015 Aug 26.

From Montefiore Medical Center (S.S., D.M., S.L.M.), Albert Einstein College of Medicine, New York, NY; Children's National Health System (A.C., F.H.), Washington, DC; Cincinnati Children's Hospital Medical Center (P.C., T.A.G.); the University of Cincinnati College of Medicine (P.C., T.A.G.), OH; The Children's Hospital of Philadelphia (D.D.), Perelman School of Medicine at the University of Pennsylvania; National Institute of Neurological Disorders and Stroke (D.G.H.), Bethesda, MD; and Baylor College of Medicine (E.M.M.), Houston, TX.

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http://dx.doi.org/10.1212/WNL.0000000000001971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603882PMC
September 2015

Summary of recommendations for the management of infantile seizures: Task Force Report for the ILAE Commission of Pediatrics.

Epilepsia 2015 Aug 30;56(8):1185-97. Epub 2015 Jun 30.

Childhood Epilepsy, Paediatric Neurology, UCL-Institute of Child Health, Great Ormond Street Hospital for Children NHS Trust, NHS Foundation Trust, London, United Kingdom.

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http://dx.doi.org/10.1111/epi.13057DOI Listing
August 2015

Association of maternal report of infant and toddler gastrointestinal symptoms with autism: evidence from a prospective birth cohort.

JAMA Psychiatry 2015 May;72(5):466-74

Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York3The Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, New York.

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http://dx.doi.org/10.1001/jamapsychiatry.2014.3034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939710PMC
May 2015

The breadth and type of systemic inflammation and the risk of adverse neurological outcomes in extremely low gestation newborns.

Pediatr Neurol 2015 Jan 16;52(1):42-8. Epub 2014 Oct 16.

Harvard Medical School, Boston, Massachusetts; Department of Neurology, Boston Children's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1016/j.pediatrneurol.2014.10.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276530PMC
January 2015

Systemic inflammation and cerebral palsy risk in extremely preterm infants.

J Child Neurol 2014 Dec 18;29(12):1692-8. Epub 2014 Mar 18.

Harvard Medical School, Boston, MA, USA Boston Children's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1177/0883073813513335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167987PMC
December 2014

Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia.

N Engl J Med 2014 Aug;371(8):699-710

From the Department of Pediatrics, Division of Hematology-Oncology, Vanderbilt-Meharry Center of Excellence in Sickle Cell Disease, Vanderbilt University School of Medicine, Nashville (M.R.D.); Department of Ophthalmology and Visual Sciences, Division of Biostatistics (M.G.), Departments of Radiology and Pediatrics (R.C.M.), Neurology and Pediatrics (M.J.N.), and Psychology (D.A.W.), the Program in Occupational Therapy and Department of Pediatrics Hematology-Oncology (A.A.K.), and the Division of Biostatistics and Department of Internal Medicine (J.P.M.), Washington University School of Medicine, St. Louis; Department of Pediatrics, Division of Hematology-Oncology, Wayne State University, Detroit (S.A.S.); Center for Cancer and Blood Disorders, Children's National Medical Center, Department of Pediatrics, George Washington University Medical Center (E.R.M.), and Department of Pediatrics, Division of Hematology-Oncology, Georgetown University Hospital (C.E.G.) - all in Washington, DC; Department of Pediatrics, Division of Hematology-Oncology, University of Alabama at Birmingham, Birmingham (T.H.H.); Department of Pediatrics, Division of Hematology-Oncology, University of Mississippi Medical Center, Jackson (S.M.); Department of Paediatrics, Evelina Children's Hospital, St. Thomas' Hospital NHS Trust (B.P.D.I.), Department of Pediatric Hematology, Royal London Hospital, Barts Health NHS Trust (P.T.T.), and the Neurosciences Unit, Institute of Child Health, University College London (F.J.K.) - all in London; Hospital for Sick Children, Department of Paediatrics, Haematology-Oncology, University of Toronto, Toronto (M.K.-A.); Division of Hematology-Oncology, Department of Pediatrics, UT Southwestern Medical Center, Dallas (T.L.M.C.); Département Pédiatrie, Hôpital Intercommunal de Creteil, Creteil, France (A.K.); Department of Pediatrics, Division of Hematology-Oncology, Baylor College of Medicine, Houston (G.A.); Department of Pediatrics, Hematology-Oncology, Univer

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http://tmed.ca/wp-content/uploads/2013/10/Transfusions-Silen
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http://www.nejm.org/doi/abs/10.1056/NEJMoa1401731
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http://dx.doi.org/10.1056/NEJMoa1401731DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195437PMC
August 2014

Headache and migraine in children with sickle cell disease are associated with lower hemoglobin and higher pain event rates but not silent cerebral infarction.

J Pediatr 2014 May 13;164(5):1175-1180.e1. Epub 2014 Feb 13.

Department of Pediatrics Vanderbilt-Meharry-Matthew Walker Center of Excellence in Sickle Cell Disease, Vanderbilt University School of Medicine, Nashville, TN. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2014.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4078657PMC
May 2014

Parental obesity and risk of autism spectrum disorder.

Pediatrics 2014 May 7;133(5):e1128-38. Epub 2014 Apr 7.

Norwegian Institute of Public Health, Oslo, Norway; Department of Public Health and Primary Health Care, University of Bergen, Bergen, Norway.

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http://dx.doi.org/10.1542/peds.2013-3664DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4006442PMC
May 2014

NINDS epilepsy and autism spectrum disorders workshop report.

Neurology 2013 Oct 2;81(18):1630-6. Epub 2013 Oct 2.

From the Department of Neurology (R.T.), Miami Children's Hospital Dan Marino Center, Weston, FL; and National Institute of Neurological Disorders and Stroke (D.H., L.A.M.), National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1212/WNL.0b013e3182a9f482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806917PMC
October 2013

Pretreatment cognitive deficits and treatment effects on attention in childhood absence epilepsy.

Neurology 2013 Oct 2;81(18):1572-80. Epub 2013 Oct 2.

From the Montefiore Medical Center (D.M., S.S., R.C.S., E.F.W.), Albert Einstein College of Medicine, New York; Children's National Medical Center (A.C., J.W.), Washington, DC; National Institute of Neurological Disorders and Stroke (D.G.H.), Bethesda, MD; and Cincinnati Children's Hospital Medical Center, and University of Cincinnati College of Medicine (P.C., T.A.G.), OH.

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http://www.neurology.org/content/81/18/1572.full.pdf
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http://www.neurology.org/cgi/doi/10.1212/WNL.0b013e3182a9f3c
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http://dx.doi.org/10.1212/WNL.0b013e3182a9f3caDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806916PMC
October 2013

Early growth patterns in children with autism.

Epidemiology 2013 Sep;24(5):660-70

Centre for Paediatric Epidemiology and Biostatistics, UCL Institute of Child Health, London, United Kingdom.

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http://dx.doi.org/10.1097/EDE.0b013e31829e1d45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3749377PMC
September 2013

Children with epilepsy in Africa: recommendations from the International Child Neurology Association/African Child Neurology Association Workshop.

J Child Neurol 2013 May 28;28(5):633-44. Epub 2013 Mar 28.

Department of Pediatric Neurology, Red Cross Children's Hospital, School of Child and Adolescent Health, University of Cape Town, South Africa.

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http://journals.sagepub.com/doi/10.1177/0883073813482974
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http://dx.doi.org/10.1177/0883073813482974DOI Listing
May 2013

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy: initial monotherapy outcomes at 12 months.

Epilepsia 2013 Jan 21;54(1):141-55. Epub 2012 Nov 21.

Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, Ohio 45229, USA.

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http://dx.doi.org/10.1111/epi.12028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3538883PMC
January 2013

Brain damage in preterm newborns and maternal medication: the ELGAN Study.

Am J Obstet Gynecol 2012 Sep 7;207(3):192.e1-9. Epub 2012 Jul 7.

Department of Epidemiology, College of Human Medicine, Michigan State University, East Lansing, MI, USA.

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http://dx.doi.org/10.1016/j.ajog.2012.06.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3432943PMC
September 2012

Comparative effectiveness and implementation research: directions for neurology.

Ann Neurol 2012 Jun;71(6):732-42

Department of Neurology, University of California at Los Angeles, CA, USA.

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http://dx.doi.org/10.1002/ana.22672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836834PMC
June 2012

Early blood gas abnormalities and the preterm brain.

Am J Epidemiol 2010 Oct 31;172(8):907-16. Epub 2010 Aug 31.

Neuroepidemiology Unit, Neurology Department, Children’s Hospital Boston, and Harvard Medical School, Boston, Massachusetts 02215-5724, USA.

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http://dx.doi.org/10.1093/aje/kwq222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984251PMC
October 2010

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy.

N Engl J Med 2010 Mar;362(9):790-9

Comprehensive Epilepsy Center, Division of Neurology, Cincinnati Children's Hospital, 3333 Burnet Ave., MLC 2015, Cincinnati, OH 45229, USA.

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http://www.nejm.org/doi/abs/10.1056/NEJMoa0902014
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http://dx.doi.org/10.1056/NEJMoa0902014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924476PMC
March 2010

Imaging biomarkers of outcome in the developing preterm brain.

Lancet Neurol 2009 Nov 30;8(11):1042-55. Epub 2009 Sep 30.

Departments of Pediatrics and Neurology, Yale University School of Medicine, New Haven, CT, USA.

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http://dx.doi.org/10.1016/S1474-4422(09)70257-1DOI Listing
November 2009

Pediatric stroke: Opportunities and challenges in planning clinical trials.

Pediatr Neurol 2006 Jun;34(6):433-5

Maimonides Infants and Children's Hospital, Developmental Medicine and Child Neurology, Brooklyn, New York 11219, USA.

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http://dx.doi.org/10.1016/j.pediatrneurol.2005.09.009DOI Listing
June 2006

Clinical trials in children--How are they implemented?

Pediatr Neurol 2006 Jun;34(6):436-8

National Institute of Neurological Disorders and Stroke/National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1016/j.pediatrneurol.2005.09.011DOI Listing
June 2006

Regulatory and ethical issues in the conduct of clinical research involving children.

Curr Opin Pediatr 2002 Dec;14(6):669-75

National Institud of Neurological Disorders and Stroke National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1097/00008480-200212000-00003DOI Listing
December 2002

Report of the National Institute of Neurological Disorders and Stroke workshop on perinatal and childhood stroke.

Pediatrics 2002 Jan;109(1):116-23

Neuroepidemiology Branch, National Institute of Neurological Disorders and Stroke, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1542/peds.109.1.116DOI Listing
January 2002