Publications by authors named "Deborah Chiabrando"

21Publications

Hereditary Ataxia: A Focus on Heme Metabolism and Fe-S Cluster Biogenesis.

Authors:
Deborah Chiabrando Francesca Bertino Emanuela Tolosano

Int J Mol Sci 2020 May 26;21(11). Epub 2020 May 26.

Molecular Biotechnology Center (MBC), Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Torino, Italy.

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May 2020

Expression and purification of the heme exporter FLVCR1a.

Authors:
Deborah Chiabrando Luigi Scietti Adriana Georgiana Prajica Francesca Bertino Emanuela Tolosano Francesca Magnani

Protein Expr Purif 2020 08 8;172:105637. Epub 2020 Apr 8.

Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Via Ferrata 9, 27100, Pavia, Italy. Electronic address:

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August 2020

The Multifaceted Role of Heme in Cancer.

Authors:
Veronica Fiorito Deborah Chiabrando Sara Petrillo Francesca Bertino Emanuela Tolosano

Front Oncol 2019 15;9:1540. Epub 2020 Jan 15.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Turin, Italy.

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January 2020

Heme and sensory neuropathy: insights from novel mutations in the heme exporter feline leukemia virus subgroup C receptor 1.

Authors:
Francesca Bertino Kyra Firestone Emanuele Bellacchio Kelly E Jackson Alexander Asamoah Joseph Hersh Veronica Fiorito Francesca Destefanis Rusty Gonser Megan E Tucker Fiorella Altruda Emanuela Tolosano Deborah Chiabrando

Pain 2019 12;160(12):2766-2775

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin, Turin, Italy.

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December 2019

Unraveling the Role of Heme in Neurodegeneration.

Authors:
Deborah Chiabrando Veronica Fiorito Sara Petrillo Emanuela Tolosano

Front Neurosci 2018 9;12:712. Epub 2018 Oct 9.

Molecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Torino, Turin, Italy.

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October 2018

Fyn kinase is a novel modulator of erythropoietin signaling and stress erythropoiesis.

Authors:
Elisabetta Beneduce Alessandro Matte Luigia De Falco Serge Mbiandjeu Deborah Chiabrando Emanuela Tolosano Enrica Federti Sara Petrillo Narla Mohandas Angela Siciliano Wilson Babu Vijay Menon Saghi Ghaffari Achille Iolascon Lucia De Franceschi

Am J Hematol 2019 01 25;94(1):10-20. Epub 2018 Oct 25.

Department of Medicine, University of Verona, AOUI Verona, Verona, Italy.

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January 2019

Mitochondrial Targeting in Neurodegeneration: A Heme Perspective.

Authors:
Veronica Fiorito Deborah Chiabrando Emanuela Tolosano

Pharmaceuticals (Basel) 2018 Sep 18;11(3). Epub 2018 Sep 18.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, 10126 Torino, Italy.

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September 2018

Heme accumulation in endothelial cells impairs angiogenesis by triggering paraptosis.

Authors:
Sara Petrillo Deborah Chiabrando Tullio Genova Veronica Fiorito Giada Ingoglia Francesca Vinchi Federico Mussano Stefano Carossa Lorenzo Silengo Fiorella Altruda Giorgio Roberto Merlo Luca Munaron Emanuela Tolosano

Cell Death Differ 2018 03 11;25(3):573-588. Epub 2017 Dec 11.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.

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March 2018

Fyn Kinase Is Involved in EPO Receptor Signaling and Is Required to Harmonize the Response to Oxidation.

Authors:
Elisabetta Beneduce Alessandro Mattè Luigia De Falco Serge Cedrick Emanuela Tolosano Deborah Chiabrando Angela Siciliano Achille Iolascon Mohandas Narla Lucia De Franceschi

Blood 2017 Dec;130(Suppl_1)

Policlinico GB Rossi, Univ. of Vero, Verona, Italy.

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December 2017

Posterior column ataxia with retinitis pigmentosa coexisting with sensory-autonomic neuropathy and leukemia due to the homozygous p.Pro221Ser FLVCR1 mutation.

Authors:
Marco Castori Silvia Morlino Martin Ungelenk Davide Pareyson Ettore Salsano Paola Grammatico Emanuela Tolosano Ingo Kurth Deborah Chiabrando

Am J Med Genet B Neuropsychiatr Genet 2017 Oct 2;174(7):732-739. Epub 2017 Aug 2.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.

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October 2017

Mutations in the Heme Exporter FLVCR1 Cause Sensory Neurodegeneration with Loss of Pain Perception.

Authors:
Deborah Chiabrando Marco Castori Maja di Rocco Martin Ungelenk Sebastian Gießelmann Matteo Di Capua Annalisa Madeo Paola Grammatico Sophie Bartsch Christian A Hübner Fiorella Altruda Lorenzo Silengo Emanuela Tolosano Ingo Kurth

PLoS Genet 2016 Dec 6;12(12):e1006461. Epub 2016 Dec 6.

Institute of Human Genetics, Jena University Hospital, Friedrich-Schiller-University Jena, Jena, Germany.

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December 2016

Alteration of heme metabolism in a cellular model of Diamond-Blackfan anemia.

Authors:
Sonia Mercurio Anna Aspesi Lorenzo Silengo Fiorella Altruda Irma Dianzani Deborah Chiabrando

Eur J Haematol 2016 Apr 25;96(4):367-74. Epub 2015 Jun 25.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Torino, Italy.

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April 2016

The heme exporter Flvcr1 regulates expansion and differentiation of committed erythroid progenitors by controlling intracellular heme accumulation.

Authors:
Sonia Mercurio Sara Petrillo Deborah Chiabrando Zuni Irma Bassi Dafne Gays Annalisa Camporeale Andrei Vacaru Barbara Miniscalco Giulio Valperga Lorenzo Silengo Fiorella Altruda Margaret H Baron Massimo Mattia Santoro Emanuela Tolosano

Haematologica 2015 Jun 20;100(6):720-9. Epub 2015 Mar 20.

Department of Molecular Biotechnology and Health Sciences and Molecular Biotechnology Center, University of Turin, Italy

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June 2015

Heme and erythropoieis: more than a structural role.

Authors:
Deborah Chiabrando Sonia Mercurio Emanuela Tolosano

Haematologica 2014 Jun;99(6):973-83

Department of Molecular Biotechnology and Health Sciences and Molecular Biotechnology Center, University of Torino, Italy

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June 2014

Heme in pathophysiology: a matter of scavenging, metabolism and trafficking across cell membranes.

Authors:
Deborah Chiabrando Francesca Vinchi Veronica Fiorito Sonia Mercurio Emanuela Tolosano

Front Pharmacol 2014 8;5:61. Epub 2014 Apr 8.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin Turin, Italy.

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June 2014

Heme exporter FLVCR1a regulates heme synthesis and degradation and controls activity of cytochromes P450.

Authors:
Francesca Vinchi Giada Ingoglia Deborah Chiabrando Sonia Mercurio Emilia Turco Lorenzo Silengo Fiorella Altruda Emanuela Tolosano

Gastroenterology 2014 May 31;146(5):1325-38. Epub 2014 Jan 31.

Molecular Biotechnology Center and Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy. Electronic address:

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May 2014

The mitochondrial heme exporter FLVCR1b mediates erythroid differentiation.

Authors:
Deborah Chiabrando Samuele Marro Sonia Mercurio Carlotta Giorgi Sara Petrillo Francesca Vinchi Veronica Fiorito Sharmila Fagoonee Annalisa Camporeale Emilia Turco Giorgio R Merlo Lorenzo Silengo Fiorella Altruda Paolo Pinton Emanuela Tolosano

J Clin Invest 2012 Dec 26;122(12):4569-79. Epub 2012 Nov 26.

Molecular Biotechnology Centre, Department of Genetics, Biology and Biochemistry, University of Torino, Torino, Italy.

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December 2012

Cell-specific regulation of Ferroportin transcription following experimentally-induced acute anemia in mice.

Authors:
Deborah Chiabrando Veronica Fiorito Samuele Marro Lorenzo Silengo Fiorella Altruda Emanuela Tolosano

Blood Cells Mol Dis 2013 Jan 24;50(1):25-30. Epub 2012 Aug 24.

Dept. of Genetics, Biology and Biochemistry, University of Torino, Italy.

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January 2013

Diamond Blackfan Anemia at the Crossroad between Ribosome Biogenesis and Heme Metabolism.

Authors:
Deborah Chiabrando Emanuela Tolosano

Adv Hematol 2010 5;2010:790632. Epub 2010 May 5.

Molecular Biotechnology Center, University of Torino, Via Nizza 52, 10126 Torino, Italy.

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July 2011

Heme controls ferroportin1 (FPN1) transcription involving Bach1, Nrf2 and a MARE/ARE sequence motif at position -7007 of the FPN1 promoter.

Authors:
Samuele Marro Deborah Chiabrando Erika Messana Jens Stolte Emilia Turco Emanuela Tolosano Martina U Muckenthaler

Haematologica 2010 Aug 23;95(8):1261-8. Epub 2010 Feb 23.

Department of Pediatric Oncology, University of Heidelberg, Im Neuenheimer Feld 153, 69120 Heidelberg, Germany.

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August 2010