Debbie Lawlor

Debbie Lawlor

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Debbie Lawlor

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Erratum to: Causal inference-so much more than statistics.

Authors:
Neil Pearce Debbie A Lawlor

Int J Epidemiol 2019 Dec 3. Epub 2019 Dec 3.

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http://dx.doi.org/10.1093/ije/dyz246DOI Listing
December 2019

Direct and BMI-mediated effect of birthweight on childhood cardio-metabolic health-a birth cohort study.

Authors:
Maria João Fonseca Milton Severo Debbie A Lawlor Henrique Barros Ana Cristina Santos

Int J Obes (Lond) 2019 Oct 22;43(10):1923-1931. Epub 2019 Jul 22.

EPIUnit - Instituto de Saúde Pública, Universidade do Porto, Porto, Portugal.

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http://dx.doi.org/10.1038/s41366-019-0413-1DOI Listing
October 2019

Paternal impact on the life course development of obesity and type 2 diabetes in the offspring.

Authors:
Gemma C Sharp Debbie A Lawlor

Diabetologia 2019 Oct 27;62(10):1802-1810. Epub 2019 Aug 27.

MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1007/s00125-019-4919-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731203PMC
October 2019

Maternal Gestational Diabetes Mellitus and Newborn DNA Methylation: Findings From the Pregnancy and Childhood Epigenetics Consortium.

Authors:
Caitlin G Howe Bianca Cox Ruby Fore James Jungius Tuomas Kvist Samantha Lent Harriet E Miles Lucas A Salas Sheryl Rifas-Shiman Anne P Starling Paul Yousefi Christine Ladd-Acosta Andrea Baccarelli Elisabeth B Binder Vaia Lida Chatzi Darina Czamara Dana Dabelea Dawn L DeMeo Akram Ghantous Zdenko Herceg Eero Kajantie Jari M T Lahti Debbie A Lawlor Augusto Litonjua Tim S Nawrot Ellen A Nohr Emily Oken Costanza Pizzi Michelle Plusquin Katri Räikkönen Caroline L Relton Gemma C Sharp Thorkild I A Sørensen Jordi Sunyer Martine Vrijheid Weiming Zhang Marie-France Hivert Carrie V Breton

Diabetes Care 2019 Oct 10. Epub 2019 Oct 10.

Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.2337/dc19-0524DOI Listing
October 2019

Determinants of Intima-Media Thickness in the Young: The ALSPAC Study.

Authors:
Scott T Chiesa Marietta Charakida Georgios Georgiopoulos Frida Dangardt Kaitlin H Wade Alicja Rapala Devina J Bhowruth Helen C Nguyen Vivek Muthurangu Rukshana Shroff George Davey Smith Debbie A Lawlor Naveed Sattar Nicholas J Timpson Alun D Hughes John E Deanfield

JACC Cardiovasc Imaging 2019 Oct 11. Epub 2019 Oct 11.

Vascular Physiology Unit, UCL Institute of Cardiovascular Science, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.jcmg.2019.08.026DOI Listing
October 2019

The Parkinson's Disease Mendelian Randomization Research Portal.

Authors:
Alastair J Noyce Sara Bandres-Ciga Jonggeol Kim Karl Heilbron Demis Kia Gibran Hemani Angli Xue Debbie A Lawlor George Davey Smith Raquel Duran Ziv Gan-Or Cornelis Blauwendraat J Raphael Gibbs David A Hinds Jian Yang Peter Visscher Jack Cuzick Huw Morris John Hardy Nicholas W Wood Mike A Nalls Andrew B Singleton

Mov Disord 2019 Oct 28. Epub 2019 Oct 28.

Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/mds.27873DOI Listing
October 2019

Metabolomics analysis in adults with high bone mass identifies a relationship between bone resorption and circulating citrate which replicates in the general population.

Authors:
April Hartley Lavinia Paternoster David M Evans William D Fraser Jonathan Tang Debbie A Lawlor Jon H Tobias Celia L Gregson

Clin Endocrinol (Oxf) 2019 Oct 30. Epub 2019 Oct 30.

Musculoskeletal Research Unit, Translation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1111/cen.14119DOI Listing
October 2019

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration.

Authors:
Xueping Liu Dorte Helenius Line Skotte Robin N Beaumont Matthias Wielscher Frank Geller Julius Juodakis Anubha Mahajan Jonathan P Bradfield Frederick T J Lin Suzanne Vogelezang Mariona Bustamante Tarunveer S Ahluwalia Niina Pitkänen Carol A Wang Jonas Bacelis Maria C Borges Ge Zhang Bruce A Bedell Robert M Rossi Kristin Skogstrand Shouneng Peng Wesley K Thompson Vivek Appadurai Debbie A Lawlor Ilkka Kalliala Christine Power Mark I McCarthy Heather A Boyd Mary L Marazita Hakon Hakonarson M Geoffrey Hayes Denise M Scholtens Fernando Rivadeneira Vincent W V Jaddoe Rebecca K Vinding Hans Bisgaard Bridget A Knight Katja Pahkala Olli Raitakari Øyvind Helgeland Stefan Johansson Pål R Njølstad João Fadista Andrew J Schork Ron Nudel Daniel E Miller Xiaoting Chen Matthew T Weirauch Preben Bo Mortensen Anders D Børglum Merete Nordentoft Ole Mors Ke Hao Kelli K Ryckman David M Hougaard Leah C Kottyan Craig E Pennell Leo-Pekka Lyytikainen Klaus Bønnelykke Martine Vrijheid Janine F Felix William L Lowe Struan F A Grant Elina Hyppönen Bo Jacobsson Marjo-Riitta Jarvelin Louis J Muglia Jeffrey C Murray Rachel M Freathy Thomas M Werge Mads Melbye Alfonso Buil Bjarke Feenstra

Nat Commun 2019 Sep 2;10(1):3927. Epub 2019 Sep 2.

Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.

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http://dx.doi.org/10.1038/s41467-019-11881-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718389PMC
September 2019

Blood pressure change across pregnancy in white British and Pakistani women: analysis of data from the Born in Bradford cohort.

Authors:
Diane Farrar Gillian Santorelli Debbie A Lawlor Derek Tuffnell Trevor A Sheldon Jane West Corrie Macdonald-Wallis

Sci Rep 2019 Sep 13;9(1):13199. Epub 2019 Sep 13.

Centre for Exercise, Nutrition and Health Sciences, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1038/s41598-019-49722-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744423PMC
September 2019

Sex and area differences in the association between adiposity and lipid profile in Malawi.

Authors:
Ana Luiza G Soares Louis Banda Alemayehu Amberbir Shabbar Jaffar Crispin Musicha Alison Price Moffat J Nyirenda Debbie A Lawlor Amelia Crampin

BMJ Glob Health 2019 11;4(5):e001542. Epub 2019 Sep 11.

Malawi Epidemiology and Intervention Research Unit (MEIRU), Lilongwe and Karonga, Malawi.

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http://dx.doi.org/10.1136/bmjgh-2019-001542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747887PMC
September 2019

Metabolic profiling of adolescent non-alcoholic fatty liver disease.

Authors:
April Hartley Diana L Santos Ferreira Emma L Anderson Debbie A Lawlor

Wellcome Open Res 2018 19;3:166. Epub 2019 Sep 19.

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.12688/wellcomeopenres.14974.2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338132.2PMC
September 2019

Data Resource Profile: The ALSPAC birth cohort as a platform to study the relationship of environment and health and social factors.

Authors:
Andy Boyd Richard Thomas Anna L Hansell John Gulliver Lucy Mary Hicks Rebecca Griggs Joshua Vande Hey Caroline M Taylor Tim Morris Jean Golding Rita Doerner Daniela Fecht John Henderson Debbie A Lawlor Nicholas J Timpson John Macleod

Int J Epidemiol 2019 08;48(4):1038-1039k

Avon Longitudinal Study Parents and Children, Population Health Science, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1093/ije/dyz063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693884PMC
August 2019

Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns.

Authors:
Nabila Kazmi Gemma C Sharp Sarah E Reese Florianne O Vehmeijer Jari Lahti Christian M Page Weiming Zhang Sheryl L Rifas-Shiman Faisal I Rezwan Andrew J Simpkin Kimberley Burrows Tom G Richardson Diana L Santos Ferreira Abigail Fraser Quaker E Harmon Shanshan Zhao Vincent W V Jaddoe Darina Czamara Elisabeth B Binder Maria C Magnus Siri E Håberg Wenche Nystad Ellen A Nohr Anne P Starling Katerina J Kechris Ivana V Yang Dawn L DeMeo Augusto A Litonjua Andrea Baccarelli Emily Oken John W Holloway Wilfried Karmaus Syed H Arshad Dana Dabelea Thorkild I A Sørensen Hannele Laivuori Katri Raikkonen Janine F Felix Stephanie J London Marie-France Hivert Tom R Gaunt Debbie A Lawlor Caroline L Relton

Hypertension 2019 08 24;74(2):375-383. Epub 2019 Jun 24.

From the MRC Integrative Epidemiology Unit (N.K., G.C.S., A.J.S., K.B., T.G.R., D.L.S.F., A.F., M.C.M., T.I.A.S., T.R.G., D.A.L., C.L.R.), University of Bristol, United Kingdom.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.12634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635125PMC
August 2019

Meta-Analysis of Genomewide Association Studies Reveals Genetic Variants for Hip Bone Geometry.

Authors:
Yi-Hsiang Hsu Karol Estrada Evangelos Evangelou Cheryl Ackert-Bicknell Kristina Akesson Thomas Beck Suzanne J Brown Terence Capellini Laura Carbone Jane Cauley Ching-Lung Cheung Steven R Cummings Stefan Czerwinski Serkalem Demissie Michael Econs Daniel Evans Charles Farber Kaare Gautvik Tamara Harris Candace Kammerer John Kemp Daniel L Koller Annie Kung Debbie Lawlor Miryoung Lee Mattias Lorentzon Fiona McGuigan Carolina Medina-Gomez Braxton Mitchell Anne Newman Carrie Nielson Claes Ohlsson Munro Peacock Sjur Reppe J Brent Richards John Robbins Gunnar Sigurdsson Timothy D Spector Kari Stefansson Elizabeth Streeten Unnur Styrkarsdottir Jonathan Tobias Katerina Trajanoska André Uitterlinden Liesbeth Vandenput Scott G Wilson Laura Yerges-Armstrong Mariel Young M Carola Zillikens Fernando Rivadeneira Douglas P Kiel David Karasik

J Bone Miner Res 2019 Jul 19;34(7):1284-1296. Epub 2019 Mar 19.

Hinda and Arthur Marcus Institute for Aging Research, Hebrew SeniorLife, Boston, MA.

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http://dx.doi.org/10.1002/jbmr.3698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650334PMC
July 2019

Association between fat mass through adolescence and arterial stiffness: a population-based study from The Avon Longitudinal Study of Parents and Children.

Authors:
Frida Dangardt Marietta Charakida Georgios Georgiopoulos Scott T Chiesa Alicja Rapala Kaitlin H Wade Alun D Hughes Nicholas J Timpson Konstantinos Pateras Nick Finer Naveed Sattar George Davey Smith Debbie A Lawlor John E Deanfield

Lancet Child Adolesc Health 2019 Jul 21;3(7):474-481. Epub 2019 May 21.

Vascular Physiology Unit, Institute of Cardiovascular Science, University College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S2352-4642(19)30105-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6558973PMC
July 2019

A Cross-Cohort Study Examining the Associations of Metabolomic Profile and Subclinical Atherosclerosis in Children and Their Parents: The Child Health CheckPoint Study and Avon Longitudinal Study of Parents and Children.

Authors:
Markus Juonala Susan Ellul Debbie A Lawlor Diana L Santos Ferreira John B Carlin Michael Cheung Terence Dwyer Melissa Wake Richard Saffery David P Burgner

J Am Heart Assoc 2019 Jul 9;8(14):e011852. Epub 2019 Jul 9.

3 Murdoch Children's Research Institute Parkville Victoria Australia.

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http://dx.doi.org/10.1161/JAHA.118.011852DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662147PMC
July 2019

Morning plasma cortisol as a cardiovascular risk factor: findings from prospective cohort and Mendelian randomization studies.

Authors:
Andrew Alexander Crawford Stefan Söderberg Clemens Kirschbaum Lee Murphy Mats Eliasson Shah Ebrahim George Davey Smith Tommy Olsson Naveed Sattar Debbie A Lawlor Nicholas J Timpson R M Reynolds Brian R Walker

Eur J Endocrinol 2019 Jul 1. Epub 2019 Jul 1.

B Walker, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom of Great Britain and Northern Ireland.

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http://dx.doi.org/10.1530/EJE-19-0161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6733337PMC
July 2019

Improving the accuracy of two-sample summary-data Mendelian randomization: moving beyond the NOME assumption.

Authors:
Jack Bowden Fabiola Del Greco M Cosetta Minelli Qingyuan Zhao Debbie A Lawlor Nuala A Sheehan John Thompson George Davey Smith

Int J Epidemiol 2019 06;48(3):728-742

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.

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http://fdslive.oup.com/www.oup.com/pdf/production_in_progres
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http://dx.doi.org/10.1093/ije/dyy258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659376PMC
June 2019

Elucidating the role of maternal environmental exposures on offspring health and disease using two-sample Mendelian randomization.

Authors:
David M Evans Gunn-Helen Moen Liang-Dar Hwang Debbie A Lawlor Nicole M Warrington

Int J Epidemiol 2019 06;48(3):861-875

University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia.

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http://dx.doi.org/10.1093/ije/dyz019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659380PMC
June 2019

Letter regarding article, "Associations of obesity and circulating insulin and glucose with breast cancer risk: a Mendelian randomization analysis".

Authors:
Vanessa Y Tan James Yarmolinsky Debbie A Lawlor Nicholas J Timpson

Int J Epidemiol 2019 06;48(3):1014-1015

Medical Research Council (MRC) Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1093/ije/dyz013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659363PMC
June 2019

Association of maternal circulating 25(OH)D and calcium with birth weight: A mendelian randomisation analysis.

Authors:
William D Thompson Jessica Tyrrell Maria-Carolina Borges Robin N Beaumont Bridget A Knight Andrew R Wood Susan M Ring Andrew T Hattersley Rachel M Freathy Debbie A Lawlor

PLoS Med 2019 06 18;16(6):e1002828. Epub 2019 Jun 18.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1002828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6581250PMC
June 2019

Associations of mortality with own blood pressure using son's blood pressure as an instrumental variable.

Authors:
David Carslake Abigail Fraser Margaret T May Tom Palmer Karri Silventoinen Per Tynelius Debbie A Lawlor George Davey Smith

Sci Rep 2019 Jun 20;9(1):8986. Epub 2019 Jun 20.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1038/s41598-019-45391-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6586810PMC
June 2019

Investigating causal relations between sleep traits and risk of breast cancer in women: mendelian randomisation study.

Authors:
Rebecca C Richmond Emma L Anderson Hassan S Dashti Samuel E Jones Jacqueline M Lane Linn Beate Strand Ben Brumpton Martin K Rutter Andrew R Wood Kurt Straif Caroline L Relton Marcus Munafò Timothy M Frayling Richard M Martin Richa Saxena Michael N Weedon Debbie A Lawlor George Davey Smith

BMJ 2019 Jun 26;365:l2327. Epub 2019 Jun 26.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1136/bmj.l2327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6592406PMC
June 2019

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Authors:
Nicole M Warrington Robin N Beaumont Momoko Horikoshi Felix R Day Øyvind Helgeland Charles Laurin Jonas Bacelis Shouneng Peng Ke Hao Bjarke Feenstra Andrew R Wood Anubha Mahajan Jessica Tyrrell Neil R Robertson N William Rayner Zhen Qiao Gunn-Helen Moen Marc Vaudel Carmen J Marsit Jia Chen Michael Nodzenski Theresia M Schnurr Mohammad H Zafarmand Jonathan P Bradfield Niels Grarup Marjolein N Kooijman Ruifang Li-Gao Frank Geller Tarunveer S Ahluwalia Lavinia Paternoster Rico Rueedi Ville Huikari Jouke-Jan Hottenga Leo-Pekka Lyytikäinen Alana Cavadino Sarah Metrustry Diana L Cousminer Ying Wu Elisabeth Thiering Carol A Wang Christian T Have Natalia Vilor-Tejedor Peter K Joshi Jodie N Painter Ioanna Ntalla Ronny Myhre Niina Pitkänen Elisabeth M van Leeuwen Raimo Joro Vasiliki Lagou Rebecca C Richmond Ana Espinosa Sheila J Barton Hazel M Inskip John W Holloway Loreto Santa-Marina Xavier Estivill Wei Ang Julie A Marsh Christoph Reichetzeder Letizia Marullo Berthold Hocher Kathryn L Lunetta Joanne M Murabito Caroline L Relton Manolis Kogevinas Leda Chatzi Catherine Allard Luigi Bouchard Marie-France Hivert Ge Zhang Louis J Muglia Jani Heikkinen Camilla S Morgen Antoine H C van Kampen Barbera D C van Schaik Frank D Mentch Claudia Langenberg Jian'an Luan Robert A Scott Jing Hua Zhao Gibran Hemani Susan M Ring Amanda J Bennett Kyle J Gaulton Juan Fernandez-Tajes Natalie R van Zuydam Carolina Medina-Gomez Hugoline G de Haan Frits R Rosendaal Zoltán Kutalik Pedro Marques-Vidal Shikta Das Gonneke Willemsen Hamdi Mbarek Martina Müller-Nurasyid Marie Standl Emil V R Appel Cilius E Fonvig Caecilie Trier Catharina E M van Beijsterveldt Mario Murcia Mariona Bustamante Sílvia Bonas-Guarch David M Hougaard Josep M Mercader Allan Linneberg Katharina E Schraut Penelope A Lind Sarah E Medland Beverley M Shields Bridget A Knight Jin-Fang Chai Kalliope Panoutsopoulou Meike Bartels Friman Sánchez Jakob Stokholm David Torrents Rebecca K Vinding Sara M Willems Mustafa Atalay Bo L Chawes Peter Kovacs Inga Prokopenko Marcus A Tuke Hanieh Yaghootkar Katherine S Ruth Samuel E Jones Po-Ru Loh Anna Murray Michael N Weedon Anke Tönjes Michael Stumvoll Kim F Michaelsen Aino-Maija Eloranta Timo A Lakka Cornelia M van Duijn Wieland Kiess Antje Körner Harri Niinikoski Katja Pahkala Olli T Raitakari Bo Jacobsson Eleftheria Zeggini George V Dedoussis Yik-Ying Teo Seang-Mei Saw Grant W Montgomery Harry Campbell James F Wilson Tanja G M Vrijkotte Martine Vrijheid Eco J C N de Geus M Geoffrey Hayes Haja N Kadarmideen Jens-Christian Holm Lawrence J Beilin Craig E Pennell Joachim Heinrich Linda S Adair Judith B Borja Karen L Mohlke Johan G Eriksson Elisabeth E Widén Andrew T Hattersley Tim D Spector Mika Kähönen Jorma S Viikari Terho Lehtimäki Dorret I Boomsma Sylvain Sebert Peter Vollenweider Thorkild I A Sørensen Hans Bisgaard Klaus Bønnelykke Jeffrey C Murray Mads Melbye Ellen A Nohr Dennis O Mook-Kanamori Fernando Rivadeneira Albert Hofman Janine F Felix Vincent W V Jaddoe Torben Hansen Charlotta Pisinger Allan A Vaag Oluf Pedersen André G Uitterlinden Marjo-Riitta Järvelin Christine Power Elina Hyppönen Denise M Scholtens William L Lowe George Davey Smith Nicholas J Timpson Andrew P Morris Nicholas J Wareham Hakon Hakonarson Struan F A Grant Timothy M Frayling Debbie A Lawlor Pål R Njølstad Stefan Johansson Ken K Ong Mark I McCarthy John R B Perry David M Evans Rachel M Freathy

Nat Genet 2019 05 1;51(5):804-814. Epub 2019 May 1.

Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Royal Devon and Exeter Hospital, Exeter, UK.

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http://dx.doi.org/10.1038/s41588-019-0403-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522365PMC
May 2019

Association of Gestational Weight Gain With Adverse Maternal and Infant Outcomes.

Authors:
Ellis Voerman Susana Santos Hazel Inskip Pilar Amiano Henrique Barros Marie-Aline Charles Leda Chatzi George P Chrousos Eva Corpeleijn Sarah Crozier Myriam Doyon Merete Eggesbø Maria Pia Fantini Sara Farchi Francesco Forastiere Vagelis Georgiu Davide Gori Wojciech Hanke Irva Hertz-Picciotto Barbara Heude Marie-France Hivert Daniel Hryhorczuk Carmen Iñiguez Anne M Karvonen Leanne K Küpers Hanna Lagström Debbie A Lawlor Irina Lehmann Per Magnus Renata Majewska Johanna Mäkelä Yannis Manios Monique Mommers Camilla S Morgen George Moschonis Ellen A Nohr Anne-Marie Nybo Andersen Emily Oken Agnieszka Pac Eleni Papadopoulou Juha Pekkanen Costanza Pizzi Kinga Polanska Daniela Porta Lorenzo Richiardi Sheryl L Rifas-Shiman Nel Roeleveld Luca Ronfani Ana C Santos Marie Standl Hein Stigum Camilla Stoltenberg Elisabeth Thiering Carel Thijs Maties Torrent Tomas Trnovec Marleen M H J van Gelder Lenie van Rossem Andrea von Berg Martine Vrijheid Alet Wijga Oleksandr Zvinchuk Thorkild I A Sørensen Keith Godfrey Vincent W V Jaddoe Romy Gaillard

JAMA 2019 05;321(17):1702-1715

Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, the Netherlands.

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2019.3820DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6506886PMC
May 2019

Exploring the role of genetic confounding in the association between maternal and offspring body mass index: evidence from three birth cohorts.

Authors:
Tom A Bond Ville Karhunen Matthias Wielscher Juha Auvinen Minna Männikkö Sirkka Keinänen-Kiukaanniemi Marc J Gunter Janine F Felix Inga Prokopenko Jian Yang Peter M Visscher David M Evans Sylvain Sebert Alex Lewin Paul F O'Reilly Debbie A Lawlor Marjo-Riitta Jarvelin

Int J Epidemiol 2019 May 10. Epub 2019 May 10.

Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.

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http://dx.doi.org/10.1093/ije/dyz095DOI Listing
May 2019

4-Hydroxyglutamate is a novel predictor of pre-eclampsia.

Authors:
Ulla Sovio Nancy McBride Angela M Wood Katya L Masconi Emma Cook Francesca Gaccioli D Stephen Charnock-Jones Debbie A Lawlor Gordon C S Smith

Int J Epidemiol 2019 May 16. Epub 2019 May 16.

Department of Obstetrics and Gynaecology, University of Cambridge; NIHR Cambridge Biomedical Research Centre, Cambridge, UK.

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http://dx.doi.org/10.1093/ije/dyz098DOI Listing
May 2019

Data on trajectories of measures of cardiovascular health in the Avon Longitudinal Study of Parents and Children (ALSPAC).

Authors:
Linda M O'Keeffe Andrew J Simpkin Kate Tilling Emma L Anderson Alun D Hughes Debbie A Lawlor Abigail Fraser Laura D Howe

Data Brief 2019 Apr 19;23:103687. Epub 2019 Jan 19.

MRC Integrative Epidemiology Unit at the University of Bristol, UK.

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http://dx.doi.org/10.1016/j.dib.2019.01.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6389726PMC
April 2019

The Effect of Pre-Analytical Conditions on Blood Metabolomics in Epidemiological Studies.

Authors:
Diana L Santos Ferreira Hannah J Maple Matt Goodwin Judith S Brand Vikki Yip Josine L Min Alix Groom Debbie A Lawlor Susan Ring

Metabolites 2019 Apr 3;9(4). Epub 2019 Apr 3.

Medical Research Council Integrative Epidemiology Unit at the University of Bristol, Bristol BS8 2BN, UK.

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https://www.mdpi.com/2218-1989/9/4/64
Publisher Site
http://dx.doi.org/10.3390/metabo9040064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6523923PMC
April 2019

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Authors:
Leanne K Küpers Claire Monnereau Gemma C Sharp Paul Yousefi Lucas A Salas Akram Ghantous Christian M Page Sarah E Reese Allen J Wilcox Darina Czamara Anne P Starling Alexei Novoloaca Samantha Lent Ritu Roy Cathrine Hoyo Carrie V Breton Catherine Allard Allan C Just Kelly M Bakulski John W Holloway Todd M Everson Cheng-Jian Xu Rae-Chi Huang Diana A van der Plaat Matthias Wielscher Simon Kebede Merid Vilhelmina Ullemar Faisal I Rezwan Jari Lahti Jenny van Dongen Sabine A S Langie Tom G Richardson Maria C Magnus Ellen A Nohr Zongli Xu Liesbeth Duijts Shanshan Zhao Weiming Zhang Michelle Plusquin Dawn L DeMeo Olivia Solomon Joosje H Heimovaara Dereje D Jima Lu Gao Mariona Bustamante Patrice Perron Robert O Wright Irva Hertz-Picciotto Hongmei Zhang Margaret R Karagas Ulrike Gehring Carmen J Marsit Lawrence J Beilin Judith M Vonk Marjo-Riitta Jarvelin Anna Bergström Anne K Örtqvist Susan Ewart Pia M Villa Sophie E Moore Gonneke Willemsen Arnout R L Standaert Siri E Håberg Thorkild I A Sørensen Jack A Taylor Katri Räikkönen Ivana V Yang Katerina Kechris Tim S Nawrot Matt J Silver Yun Yun Gong Lorenzo Richiardi Manolis Kogevinas Augusto A Litonjua Brenda Eskenazi Karen Huen Hamdi Mbarek Rachel L Maguire Terence Dwyer Martine Vrijheid Luigi Bouchard Andrea A Baccarelli Lisa A Croen Wilfried Karmaus Denise Anderson Maaike de Vries Sylvain Sebert Juha Kere Robert Karlsson Syed Hasan Arshad Esa Hämäläinen Michael N Routledge Dorret I Boomsma Andrew P Feinberg Craig J Newschaffer Eva Govarts Matthieu Moisse M Daniele Fallin Erik Melén Andrew M Prentice Eero Kajantie Catarina Almqvist Emily Oken Dana Dabelea H Marike Boezen Phillip E Melton Rosalind J Wright Gerard H Koppelman Letizia Trevisi Marie-France Hivert Jordi Sunyer Monica C Munthe-Kaas Susan K Murphy Eva Corpeleijn Joseph Wiemels Nina Holland Zdenko Herceg Elisabeth B Binder George Davey Smith Vincent W V Jaddoe Rolv T Lie Wenche Nystad Stephanie J London Debbie A Lawlor Caroline L Relton Harold Snieder Janine F Felix

Nat Commun 2019 04 23;10(1):1893. Epub 2019 Apr 23.

The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478731PMC
April 2019

Combined Association of Body Mass Index and Alcohol Consumption With Biomarkers for Liver Injury and Incidence of Liver Disease: A Mendelian Randomization Study.

Authors:
Alice R Carter Maria-Carolina Borges Marianne Benn Anne Tybjærg-Hansen George Davey Smith Børge G Nordestgaard Debbie A Lawlor

JAMA Netw Open 2019 03 1;2(3):e190305. Epub 2019 Mar 1.

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484655PMC
March 2019

Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies.

Authors:
Lisa Pennells Stephen Kaptoge Angela Wood Mike Sweeting Xiaohui Zhao Ian White Stephen Burgess Peter Willeit Thomas Bolton Karel G M Moons Yvonne T van der Schouw Randi Selmer Kay-Tee Khaw Vilmundur Gudnason Gerd Assmann Philippe Amouyel Veikko Salomaa Mika Kivimaki Børge G Nordestgaard Michael J Blaha Lewis H Kuller Hermann Brenner Richard F Gillum Christa Meisinger Ian Ford Matthew W Knuiman Annika Rosengren Debbie A Lawlor Henry Völzke Cyrus Cooper Alejandro Marín Ibañez Edoardo Casiglia Jussi Kauhanen Jackie A Cooper Beatriz Rodriguez Johan Sundström Elizabeth Barrett-Connor Rachel Dankner Paul J Nietert Karina W Davidson Robert B Wallace Dan G Blazer Cecilia Björkelund Chiara Donfrancesco Harlan M Krumholz Aulikki Nissinen Barry R Davis Sean Coady Peter H Whincup Torben Jørgensen Pierre Ducimetiere Maurizio Trevisan Gunnar Engström Carlos J Crespo Tom W Meade Marjolein Visser Daan Kromhout Stefan Kiechl Makoto Daimon Jackie F Price Agustin Gómez de la Cámara J Wouter Jukema Benoît Lamarche Altan Onat Leon A Simons Maryam Kavousi Yoav Ben-Shlomo John Gallacher Jacqueline M Dekker Hisatomi Arima Nawar Shara Robert W Tipping Ronan Roussel Eric J Brunner Wolfgang Koenig Masaru Sakurai Jelena Pavlovic Ron T Gansevoort Dorothea Nagel Uri Goldbourt Elizabeth L M Barr Luigi Palmieri Inger Njølstad Shinichi Sato W M Monique Verschuren Cherian V Varghese Ian Graham Oyere Onuma Philip Greenland Mark Woodward Majid Ezzati Bruce M Psaty Naveed Sattar Rod Jackson Paul M Ridker Nancy R Cook Ralph B D'Agostino Simon G Thompson John Danesh Emanuele Di Angelantonio

Eur Heart J 2019 02;40(7):621-631

Department of Public Health and Primary Care, University of Cambridge, 2 Worts' Causeway, Cambridge, UK.

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http://dx.doi.org/10.1093/eurheartj/ehy653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374687PMC
February 2019

Associations of maternal vitamin D, PTH and calcium with hypertensive disorders of pregnancy and associated adverse perinatal outcomes: Findings from the Born in Bradford cohort study.

Authors:
Gillian Santorelli Donald Whitelaw Diane Farrar Jane West Debbie A Lawlor

Sci Rep 2019 Feb 4;9(1):1205. Epub 2019 Feb 4.

MRC Integrated Epidemiology Unit at the University of Bristol, Rm OS11, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1038/s41598-018-37600-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362043PMC
February 2019

Maternal body mass index, gestational weight gain, and the risk of overweight and obesity across childhood: An individual participant data meta-analysis.

Authors:
Ellis Voerman Susana Santos Bernadeta Patro Golab Pilar Amiano Ferran Ballester Henrique Barros Anna Bergström Marie-Aline Charles Leda Chatzi Cécile Chevrier George P Chrousos Eva Corpeleijn Nathalie Costet Sarah Crozier Graham Devereux Merete Eggesbø Sandra Ekström Maria Pia Fantini Sara Farchi Francesco Forastiere Vagelis Georgiu Keith M Godfrey Davide Gori Veit Grote Wojciech Hanke Irva Hertz-Picciotto Barbara Heude Daniel Hryhorczuk Rae-Chi Huang Hazel Inskip Nina Iszatt Anne M Karvonen Louise C Kenny Berthold Koletzko Leanne K Küpers Hanna Lagström Irina Lehmann Per Magnus Renata Majewska Johanna Mäkelä Yannis Manios Fionnuala M McAuliffe Sheila W McDonald John Mehegan Monique Mommers Camilla S Morgen Trevor A Mori George Moschonis Deirdre Murray Carol Ní Chaoimh Ellen A Nohr Anne-Marie Nybo Andersen Emily Oken Adriëtte J J M Oostvogels Agnieszka Pac Eleni Papadopoulou Juha Pekkanen Costanza Pizzi Kinga Polanska Daniela Porta Lorenzo Richiardi Sheryl L Rifas-Shiman Luca Ronfani Ana C Santos Marie Standl Camilla Stoltenberg Elisabeth Thiering Carel Thijs Maties Torrent Suzanne C Tough Tomas Trnovec Steve Turner Lenie van Rossem Andrea von Berg Martine Vrijheid Tanja G M Vrijkotte Jane West Alet Wijga John Wright Oleksandr Zvinchuk Thorkild I A Sørensen Debbie A Lawlor Romy Gaillard Vincent W V Jaddoe

PLoS Med 2019 02 11;16(2):e1002744. Epub 2019 Feb 11.

The Generation R Study Group, Erasmus University Medical Center, Rotterdam, the Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6370184PMC
February 2019

Experiencing menopause in the UK: The interrelated narratives of normality, distress, and transformation.

Authors:
Isabel de Salis Amanda Owen-Smith Jenny L Donovan Debbie A Lawlor

J Women Aging 2018 Nov-Dec;30(6):520-540. Epub 2017 Nov 2.

a School of Social and Community Medicine , University of Bristol , Bristol , UK.

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http://dx.doi.org/10.1080/08952841.2018.1396783DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191885PMC
January 2019

Early vascular damage from smoking and alcohol in teenage years: the ALSPAC study.

Authors:
Marietta Charakida George Georgiopoulos Frida Dangardt Scott T Chiesa Alun D Hughes Alicja Rapala George Davey Smith Debbie Lawlor Nicholas Finer John E Deanfield

Eur Heart J 2019 Jan;40(4):345-353

Institute of Cardiovascular Science, University College London, UK.

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http://dx.doi.org/10.1093/eurheartj/ehy524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340100PMC
January 2019

Maternal reproductive hormones and angiogenic factors in pregnancy and subsequent breast cancer risk.

Authors:
Rosie Cornish Anne Cathrine Staff Andy Boyd Debbie A Lawlor Steinar Tretli Gary Bradwin Thomas F McElrath Marianne Hyer Robert N Hoover Rebecca Troisi

Cancer Causes Control 2019 Jan 1;30(1):63-74. Epub 2018 Dec 1.

Epidemiology and Biostatistics Program, Division of Epidemiology and Genetics, National Cancer Institute, 9609 Medical Center Drive, Rockville, MD, 20850, USA.

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http://dx.doi.org/10.1007/s10552-018-1100-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438198PMC
January 2019

Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms.

Authors:
Samuel E Jones Jacqueline M Lane Andrew R Wood Vincent T van Hees Jessica Tyrrell Robin N Beaumont Aaron R Jeffries Hassan S Dashti Melvyn Hillsdon Katherine S Ruth Marcus A Tuke Hanieh Yaghootkar Seth A Sharp Yingjie Jie William D Thompson Jamie W Harrison Amy Dawes Enda M Byrne Henning Tiemeier Karla V Allebrandt Jack Bowden David W Ray Rachel M Freathy Anna Murray Diego R Mazzotti Philip R Gehrman Debbie A Lawlor Timothy M Frayling Martin K Rutter David A Hinds Richa Saxena Michael N Weedon

Nat Commun 2019 01 29;10(1):343. Epub 2019 Jan 29.

Genetics of Complex Traits, University of Exeter Medical School, Royal Devon & Exeter Hospital, Exeter, EX2 5DW, UK.

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http://dx.doi.org/10.1038/s41467-018-08259-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6351539PMC
January 2019

A genome-wide association study of mitochondrial DNA copy number in two population-based cohorts.

Authors:
Anna L Guyatt Rebecca R Brennan Kimberley Burrows Philip A I Guthrie Raimondo Ascione Susan M Ring Tom R Gaunt Angela Pyle Heather J Cordell Debbie A Lawlor Patrick F Chinnery Gavin Hudson Santiago Rodriguez

Hum Genomics 2019 01 31;13(1). Epub 2019 Jan 31.

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1186/s40246-018-0190-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357493PMC
January 2019

Influence of maternal obesity on the association between common pregnancy complications and risk of childhood obesity: an individual participant data meta-analysis.

Authors:
Bernadeta Patro Golab Susana Santos Ellis Voerman Debbie A Lawlor Vincent W V Jaddoe Romy Gaillard

Lancet Child Adolesc Health 2018 11 7;2(11):812-821. Epub 2018 Sep 7.

The Generation R Study Group, Erasmus MC, University Medical Center, Rotterdam, Netherlands; Department of Paediatrics, Erasmus MC, University Medical Center, Rotterdam, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/S2352-4642(18)30273-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196075PMC
November 2018

Sex-specific trajectories of measures of cardiovascular health during childhood and adolescence: A prospective cohort study.

Authors:
Linda M O'Keeffe Andrew J Simpkin Kate Tilling Emma L Anderson Alun D Hughes Debbie A Lawlor Abigail Fraser Laura D Howe

Atherosclerosis 2018 11 27;278:190-196. Epub 2018 Sep 27.

MRC Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS82BN, UK; Population Health Sciences, Bristol Medical School, Oakfield House, Oakfield Grove, Bristol, BS82BN, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S00219150183140
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November 2018

Elevated Blood Pressure in Adolescence Is Attributable to a Combination of Elevated Cardiac Output and Total Peripheral Resistance.

Authors:
Chloe Park Abigail Fraser Laura D Howe Siana Jones George Davey Smith Debbie A Lawlor Nish Chaturvedi Alun D Hughes

Hypertension 2018 11;72(5):1103-1108

From the Department of Population Science and Experimental Medicine, Institute of Cardiovascular Sciences, University College London, United Kingdom (C.P., S.J., N.C., A.D.H.).

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https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.118.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181289PMC
November 2018

Gestational diabetes and ultrasound-assessed fetal growth in South Asian and White European women: findings from a prospective pregnancy cohort.

Authors:
Judith S Brand Jane West Derek Tuffnell Philippa K Bird John Wright Kate Tilling Debbie A Lawlor

BMC Med 2018 11 6;16(1):203. Epub 2018 Nov 6.

MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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https://bmcmedicine.biomedcentral.com/articles/10.1186/s1291
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219043PMC
November 2018

Gestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania.

Authors:
Susana Santos Iris Eekhout Ellis Voerman Romy Gaillard Henrique Barros Marie-Aline Charles Leda Chatzi Cécile Chevrier George P Chrousos Eva Corpeleijn Nathalie Costet Sarah Crozier Myriam Doyon Merete Eggesbø Maria Pia Fantini Sara Farchi Francesco Forastiere Luigi Gagliardi Vagelis Georgiu Keith M Godfrey Davide Gori Veit Grote Wojciech Hanke Irva Hertz-Picciotto Barbara Heude Marie-France Hivert Daniel Hryhorczuk Rae-Chi Huang Hazel Inskip Todd A Jusko Anne M Karvonen Berthold Koletzko Leanne K Küpers Hanna Lagström Debbie A Lawlor Irina Lehmann Maria-Jose Lopez-Espinosa Per Magnus Renata Majewska Johanna Mäkelä Yannis Manios Sheila W McDonald Monique Mommers Camilla S Morgen George Moschonis Ľubica Murínová John Newnham Ellen A Nohr Anne-Marie Nybo Andersen Emily Oken Adriëtte J J M Oostvogels Agnieszka Pac Eleni Papadopoulou Juha Pekkanen Costanza Pizzi Kinga Polanska Daniela Porta Lorenzo Richiardi Sheryl L Rifas-Shiman Nel Roeleveld Loreto Santa-Marina Ana C Santos Henriette A Smit Thorkild I A Sørensen Marie Standl Maggie Stanislawski Camilla Stoltenberg Elisabeth Thiering Carel Thijs Maties Torrent Suzanne C Tough Tomas Trnovec Marleen M H J van Gelder Lenie van Rossem Andrea von Berg Martine Vrijheid Tanja G M Vrijkotte Oleksandr Zvinchuk Stef van Buuren Vincent W V Jaddoe

BMC Med 2018 11 5;16(1):201. Epub 2018 Nov 5.

The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, 3000 CA, Rotterdam, the Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217770PMC
November 2018

Metabolomic Consequences of Genetic Inhibition of PCSK9 Compared With Statin Treatment

Authors:
Eeva Sliz Johannes Kettunen Michael Holmes Clare Williams Charles Boachie Qin Wang Minna Männikkö Sylvain Sebert Robin Walters Kuang Lin Lona Millwood Robert Clarke Liming Li N Rankin Paul Welsh Christian Delles J Jukema Stella Trompet Ian Ford Markus Perola Veikko Salomaa Marjo-Riitta Järvelin Zhengming Chen Debbie Lawlor Mika Ala-Korpela John Danesh George Smith Naveed Sattar Adam Butterworth Peter Würtz

Circulation 2018 Nov;138(22):2499–2512

Diabetes and Obesity Research Program, University of Helsinki, Finland

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254781PMC
November 2018

Assessing the causal role of body mass index on cardiovascular health in young adults: Mendelian randomization and recall-by-genotype analyses.

Authors:
Kaitlin H Wade Scott T Chiesa Alun D Hughes Nish Chaturvedi Marietta Charakida Alicja Rapala Vivek Muthurangu Tauseef Khan Nicholas Finer Naveed Sattar Laura D Howe Abigail Fraser Debbie A Lawlor George Davey Smith John E Deanfield Nicholas J Timpson

Circulation 2018 11 30;138(20):2187-2201. Epub 2018 Jul 30.

MRC Integrative Epidemiology Unit (IEU) at the University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.117.033278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250296PMC
November 2018

Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment.

Authors:
Eeva Sliz Johannes Kettunen Michael V Holmes Clare Oliver Williams Charles Boachie Qin Wang Minna Männikkö Sylvain Sebert Robin Walters Kuang Lin Iona Y Millwood Robert Clarke Liming Li Naomi Rankin Paul Welsh Christian Delles J Wouter Jukema Stella Trompet Ian Ford Markus Perola Veikko Salomaa Marjo-Riitta Järvelin Zhengming Chen Debbie A Lawlor Mika Ala-Korpela John Danesh George Davey Smith Naveed Sattar Adam Butterworth Peter Würtz

Circulation 2018 11 15;138(22):2499-2512. Epub 2018 Aug 15.

Diabetes and Obesity Research Program, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034942DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254781PMC
November 2018

Socioeconomic differences in childhood BMI trajectories in Belarus.

Authors:
Rita Patel Kate Tilling Debbie A Lawlor Laura D Howe Rachael A Hughes Natalia Bogdanovich Lidia Matush Emily Nicoli Emily Oken Michael S Kramer Richard M Martin

Int J Obes (Lond) 2018 09 28;42(9):1651-1660. Epub 2018 Feb 28.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1038/s41366-018-0042-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033313PMC
September 2018

Author Correction: Associations of social and economic and pregnancy exposures with blood pressure in UK White British and Pakistani children age 4/5.

Authors:
Jane West Debbie A Lawlor Gillian Santorelli Paul Collings Peter H Whincup Naveed A Sattar Diane Farrar John Wright

Sci Rep 2018 Sep 26;8(1):14591. Epub 2018 Sep 26.

Bradford Institute for Health Research, Bradford, UK.

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http://www.nature.com/articles/s41598-018-32318-0
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158281PMC
September 2018

Exploring the association of genetic factors with participation in the Avon Longitudinal Study of Parents and Children.

Authors:
Amy E Taylor Hannah J Jones Hannah Sallis Jack Euesden Evie Stergiakouli Neil M Davies Stanley Zammit Debbie A Lawlor Marcus R Munafò George Davey Smith Kate Tilling

Int J Epidemiol 2018 08;47(4):1207-1216

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1093/ije/dyy060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6124613PMC
August 2018

Mendelian randomization study shows no causal relationship between circulating urate levels and Parkinson's disease.

Authors:
Demis A Kia Alastair J Noyce Jon White Doug Speed Aude Nicolas Stephen Burgess Debbie A Lawlor George Davey Smith Andrew Singleton Mike A Nalls Reecha Sofat Nicholas W Wood

Ann Neurol 2018 08;84(2):191-199

Department of Molecular Neuroscience, UCL Institute of Neurology, London, United Kingdom.

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http://dx.doi.org/10.1002/ana.25294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6481555PMC
August 2018

Associations of Y chromosomal haplogroups with cardiometabolic risk factors and subclinical vascular measures in males during childhood and adolescence.

Authors:
Linda M O'Keeffe Laura D Howe Abigail Fraser Alun D Hughes Kaitlin H Wade Emma L Anderson Debbie A Lawlor A Mesut Erzurumluoglu George Davey-Smith Santiago Rodriguez Evie Stergiakouli

Atherosclerosis 2018 07 25;274:94-103. Epub 2018 Apr 25.

MRC Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS82BN, UK; Population Health Sciences, Bristol Medical School, Oakfield House, Oakfield Grove, Bristol, BS82BN, UK; School of Oral and Dental Sciences, University of Bristol, UK.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.04.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013646PMC
July 2018

Newborn weight change and childhood cardio-metabolic traits - a prospective cohort study.

Authors:
Maria João Fonseca Milton Severo Debbie A Lawlor Henrique Barros Ana Cristina Santos

BMC Pediatr 2018 07 2;18(1):211. Epub 2018 Jul 2.

EPIUnit - Instituto de Saúde Pública, Universidade do Porto, Rua das Taipas n° 135, 4050-600, Porto, Portugal.

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http://dx.doi.org/10.1186/s12887-018-1184-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029387PMC
July 2018

Prevalence of Prenatal Depression Symptoms Among 2 Generations of Pregnant Mothers: The Avon Longitudinal Study of Parents and Children.

Authors:
Rebecca M Pearson Rebecca E Carnegie Callum Cree Claire Rollings Louise Rena-Jones Jonathan Evans Alan Stein Kate Tilling Melanie Lewcock Debbie A Lawlor

JAMA Netw Open 2018 07 6;1(3):e180725. Epub 2018 Jul 6.

Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1001/jamanetworkopen.2018.0725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324308PMC
July 2018

Associations of social and economic and pregnancy exposures with blood pressure in UK White British and Pakistani children age 4/5.

Authors:
Jane West Debbie A Lawlor Gillian Santorelli Paul Collings Peter H Whincup Naveed A Sattar Diane Farrar John Wright

Sci Rep 2018 06 12;8(1):8966. Epub 2018 Jun 12.

Bradford Institute for Health Research, Bradford, UK.

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http://dx.doi.org/10.1038/s41598-018-27316-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997744PMC
June 2018

Vitamin D and risk of pregnancy related hypertensive disorders: mendelian randomisation study.

Authors:
Maria C Magnus Kozeta Miliku Anna Bauer Stephanie M Engel Janine F Felix Vincent W V Jaddoe Debbie A Lawlor Stephanie J London Per Magnus Ralph McGinnis Wenche Nystad Christian M Page Fernando Rivadeneira Lars C Stene German Tapia Nicholas Williams Carolina Bonilla Abigail Fraser

BMJ 2018 06 20;361:k2167. Epub 2018 Jun 20.

Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008987PMC
http://dx.doi.org/10.1136/bmj.k2167DOI Listing
June 2018

Letter by Hartwig et al Regarding Article, "Evaluation of the Pleiotropic Effects of Statins: A Reanalysis of the Randomized Trial Evidence Using Egger Regression".

Authors:
Fernando Pires Hartwig Maria Carolina Borges Debbie A Lawlor

Arterioscler Thromb Vasc Biol 2018 05;38(5):e85-e86

Medical Research Council Integrative Epidemiology Unit, University of Bristol, United Kingdom.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.118.310897
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May 2018

Derivative estimation for longitudinal data analysis: Examining features of blood pressure measured repeatedly during pregnancy.

Authors:
Andrew J Simpkin Maria Durban Debbie A Lawlor Corrie MacDonald-Wallis Margaret T May Chris Metcalfe Kate Tilling

Stat Med 2018 May 20. Epub 2018 May 20.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1002/sim.7694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099422PMC
May 2018

Associations Between Maternal Prepregnancy Body Mass Index and Gestational Weight Gain and Daughter's Age at Menarche: The Avon Longitudinal Study of Parents and Children.

Authors:
Rebecca B Lawn Debbie A Lawlor Abigail Fraser

Am J Epidemiol 2018 04;187(4):677-686

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1093/aje/kwx308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5888997PMC
April 2018

How does the association of general and central adiposity with glycaemia and blood pressure differ by gender and area of residence in a Malawian population: a cross-sectional study.

Authors:
Kathleen Mudie Debbie A Lawlor Neil Pearce Amelia Crampin Laurie Tomlinson Terence Tafatatha Crispin Musicha Dorothea Nitsch Liam Smeeth Moffat J Nyirenda

Int J Epidemiol 2018 Apr 10. Epub 2018 Apr 10.

Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

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https://academic.oup.com/ije/article/47/3/887/4965904
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http://dx.doi.org/10.1093/ije/dyy047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005143PMC
April 2018

Association of Genetic Instrumental Variables for Lung Function on Coronary Artery Disease Risk: A 2-Sample Mendelian Randomization Study.

Authors:
Shiu Lun Au Yeung Maria-Carolina Borges Debbie A Lawlor

Circ Genom Precis Med 2018 04;11(4):e001952

School of Public Health, University of Hong Kong, Hong Kong Special Administrative Region, China (S.L.A.Y.); and MRC Integrative Epidemiology Unit (M.- C.B., D.A.L.) and Population Health Sciences (M.-C.B., D.A.L.), Bristol Medical School, University of Bristol, United Kingdom.

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http://dx.doi.org/10.1161/CIRCGEN.117.001952DOI Listing
April 2018

Cardiometabolic phenotypes and mitochondrial DNA copy number in two cohorts of UK women.

Authors:
Anna L Guyatt Kimberley Burrows Philip A I Guthrie Sue Ring Wendy McArdle Ian N M Day Raimondo Ascione Debbie A Lawlor Tom R Gaunt Santiago Rodriguez

Mitochondrion 2018 03 15;39:9-19. Epub 2017 Aug 15.

MRC Integrative Epidemiology Unit, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK; School of Social and Community Medicine, University of Bristol, Oakfield House, Oakfield Grove, Bristol BS8 2BN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mito.2017.08.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832987PMC
March 2018

Prevalence of obesity, hypertension, and diabetes, and cascade of care in sub-Saharan Africa: a cross-sectional, population-based study in rural and urban Malawi.

Authors:
Alison J Price Amelia C Crampin Alemayehu Amberbir Ndoliwe Kayuni-Chihana Crispin Musicha Terence Tafatatha Keith Branson Debbie A Lawlor Elenaus Mwaiyeghele Lawrence Nkhwazi Liam Smeeth Neil Pearce Elizabeth Munthali Beatrice M Mwagomba Charles Mwansambo Judith R Glynn Shabbar Jaffar Moffat Nyirenda

Lancet Diabetes Endocrinol 2018 03 19;6(3):208-222. Epub 2018 Jan 19.

Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK; Malawi Epidemiology and Intervention Research Unit, Lilongwe and Karonga, Malawi.

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http://dx.doi.org/10.1016/S2213-8587(17)30432-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5835666PMC
March 2018

Associations of adversity in childhood and risk factors for cardiovascular disease in mid-adulthood.

Authors:
Emma L Anderson Abigail Fraser Rishi Caleyachetty Rebecca Hardy Debbie A Lawlor Laura D Howe

Child Abuse Negl 2018 02 2;76:138-148. Epub 2017 Nov 2.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK; School of Social and Community Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1016/j.chiabu.2017.10.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915314PMC
February 2018

Genome-wide association study of offspring birth weight in 86 577 women identifies five novel loci and highlights maternal genetic effects that are independent of fetal genetics.

Authors:
Robin N Beaumont Nicole M Warrington Alana Cavadino Jessica Tyrrell Michael Nodzenski Momoko Horikoshi Frank Geller Ronny Myhre Rebecca C Richmond Lavinia Paternoster Jonathan P Bradfield Eskil Kreiner-Møller Ville Huikari Sarah Metrustry Kathryn L Lunetta Jodie N Painter Jouke-Jan Hottenga Catherine Allard Sheila J Barton Ana Espinosa Julie A Marsh Catherine Potter Ge Zhang Wei Ang Diane J Berry Luigi Bouchard Shikta Das Hakon Hakonarson Jani Heikkinen Øyvind Helgeland Berthold Hocher Albert Hofman Hazel M Inskip Samuel E Jones Manolis Kogevinas Penelope A Lind Letizia Marullo Sarah E Medland Anna Murray Jeffrey C Murray Pål R Njølstad Ellen A Nohr Christoph Reichetzeder Susan M Ring Katherine S Ruth Loreto Santa-Marina Denise M Scholtens Sylvain Sebert Verena Sengpiel Marcus A Tuke Marc Vaudel Michael N Weedon Gonneke Willemsen Andrew R Wood Hanieh Yaghootkar Louis J Muglia Meike Bartels Caroline L Relton Craig E Pennell Leda Chatzi Xavier Estivill John W Holloway Dorret I Boomsma Grant W Montgomery Joanne M Murabito Tim D Spector Christine Power Marjo-Ritta Järvelin Hans Bisgaard Struan F A Grant Thorkild I A Sørensen Vincent W Jaddoe Bo Jacobsson Mads Melbye Mark I McCarthy Andrew T Hattersley M Geoffrey Hayes Timothy M Frayling Marie-France Hivert Janine F Felix Elina Hyppönen William L Lowe David M Evans Debbie A Lawlor Bjarke Feenstra Rachel M Freathy

Hum Mol Genet 2018 02;27(4):742-756

Institute of Biomedical and Clinical Science, University of Exeter Medical School, University of Exeter, Royal Devon and Exeter Hospital, Exeter EX2 5DW, UK.

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http://dx.doi.org/10.1093/hmg/ddx429DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886200PMC
February 2018

Metabolic characterization of menopause: cross-sectional and longitudinal evidence.

Authors:
Qin Wang Diana L Santos Ferreira Scott M Nelson Naveed Sattar Mika Ala-Korpela Debbie A Lawlor

BMC Med 2018 02 6;16(1):17. Epub 2018 Feb 6.

MRC Integrative Epidemiology Unit at the University of Bristol, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1186/s12916-018-1008-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800033PMC
February 2018

Age at Menarche and Cardiometabolic Health: A Sibling Analysis in the Scottish Family Health Study.

Authors:
Maria C Magnus Debbie A Lawlor Stamatina Iliodromiti Sandosh Padmanabhan Scott M Nelson Abigail Fraser

J Am Heart Assoc 2018 02 10;7(4). Epub 2018 Feb 10.

MRC Integrative Epidemiology Unit at the University of Bristol, United Kingdom.

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http://dx.doi.org/10.1161/JAHA.117.007780DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850196PMC
February 2018

Maternal thyroid function and child educational attainment: prospective cohort study.

Authors:
Scott M Nelson Caroline Haig Alex McConnachie Naveed Sattar Susan M Ring George D Smith Debbie A Lawlor Robert S Lindsay

BMJ 2018 02 20;360:k452. Epub 2018 Feb 20.

Institute of Cardiovascular and Medical Sciences, British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5819484PMC
http://dx.doi.org/10.1136/bmj.k452DOI Listing
February 2018

Association of maternal exposures with adiposity at age 4/5 years in white British and Pakistani children: findings from the Born in Bradford study.

Authors:
Jane West Gillian Santorelli Peter H Whincup Lesley Smith Naveed A Sattar Noel Cameron Diane Farrar Paul Collings John Wright Debbie A Lawlor

Diabetologia 2018 Jan 24;61(1):242-252. Epub 2017 Oct 24.

MRC Integrated Epidemiology Unit at the University of Bristol, Rm OS11, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1007/s00125-017-4457-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046463PMC
January 2018

Physical activity phenotyping with activity bigrams, and their association with BMI.

Authors:
Louise A C Millard Kate Tilling Debbie A Lawlor Peter A Flach Tom R Gaunt

Int J Epidemiol 2017 12;46(6):1857-1870

MRC Integrative Epidemiology Unit (IEU).

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http://dx.doi.org/10.1093/ije/dyx093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837541PMC
December 2017

Metabolic Profiling of Adiponectin Levels in Adults: Mendelian Randomization Analysis.

Authors:
Maria Carolina Borges Aluísio J D Barros Diana L Santos Ferreira Juan Pablo Casas Bernardo Lessa Horta Mika Kivimaki Meena Kumari Usha Menon Tom R Gaunt Yoav Ben-Shlomo Deise F Freitas Isabel O Oliveira Aleksandra Gentry-Maharaj Evangelia Fourkala Debbie A Lawlor Aroon D Hingorani

Circ Cardiovasc Genet 2017 Dec;10(6)

From the Post-Graduate Program in Epidemiology, Federal University of Pelotas, Brazil (M.C.B., A.J.D.B., B.L.H., D.F.F., I.O.O.); MRC Integrative Epidemiology Unit (M.C.B., D.L.S.F., T.R.G., D.A.L.) and Population Health Sciences, Bristol Medical School (M.C.B., D.L.S.F., T.R.G., Y.B.-S., D.A.L.), University of Bristol, United Kingdom; Farr Institute of Health Informatics (J.P.C., A.D.H.), Department of Epidemiology and Public Health (M. Kivimaki, M. Kumari), Department of Women's Cancer, Institute for Women's Health, Faculty of Population Health Sciences (U.M., A.G.-M., E.F.), and Institute of Cardiovascular Science (A.D.H.), University College London, United Kingdom; Institute for Social and Economic Research, University of Essex, United Kingdom (M. Kumari); and Department of Physiology and Pharmacology, Institute of Biology, Federal University of Pelotas, Brazil (I.O.O.).

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http://dx.doi.org/10.1161/CIRCGENETICS.117.001837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736126PMC
December 2017

Number of Offspring and Cardiovascular Disease Risk in Men and Women: The Role of Shared Lifestyle Characteristics.

Authors:
Maria C Magnus Stamatina Iliodromiti Debbie A Lawlor Janet M Catov Scott M Nelson Abigail Fraser

Epidemiology 2017 11;28(6):880-888

From the aMRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom; bSchool of Social and Community Medicine, University of Bristol, Bristol, United Kingdom; cDomain for Mental and Physical Health, Norwegian Institute of Public Health, Oslo, Norway; dSchool of Medicine, University of Glasgow, Glasgow, Scotland; and eDepartment of Obstetrics and Gynecology, University of Pittsburgh, Pittsburgh, PA.

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http://dx.doi.org/10.1097/EDE.0000000000000712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5625954PMC
November 2017

The role of glycaemic and lipid risk factors in mediating the effect of BMI on coronary heart disease: a two-step, two-sample Mendelian randomisation study.

Authors:
Lin Xu Maria Carolina Borges Gibran Hemani Debbie A Lawlor

Diabetologia 2017 11 9;60(11):2210-2220. Epub 2017 Sep 9.

MRC Integrative Epidemiology Unit, University of Bristol, Rm OS11, Oakfield House, Oakfield Grove, Bristol, BS8 2BN, UK.

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http://dx.doi.org/10.1007/s00125-017-4396-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6342872PMC
November 2017

Prediction of uncomplicated pregnancies in obese women: a prospective multicentre study.

Authors:
Matias C Vieira Sara L White Nashita Patel Paul T Seed Annette L Briley Jane Sandall Paul Welsh Naveed Sattar Scott M Nelson Debbie A Lawlor Lucilla Poston Dharmintra Pasupathy

BMC Med 2017 11 3;15(1):194. Epub 2017 Nov 3.

Department of Women and Children's Health, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, SE1 7EH, UK.

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http://dx.doi.org/10.1186/s12916-017-0956-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669007PMC
November 2017

Quantitative Serum Nuclear Magnetic Resonance Metabolomics in Large-Scale Epidemiology: A Primer on -Omic Technologies.

Authors:
Peter Würtz Antti J Kangas Pasi Soininen Debbie A Lawlor George Davey Smith Mika Ala-Korpela

Am J Epidemiol 2017 Nov;186(9):1084-1096

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http://dx.doi.org/10.1093/aje/kwx016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860146PMC
November 2017

Metabolic profiling of gestational diabetes in obese women during pregnancy.

Authors:
Sara L White Dharmintra Pasupathy Naveed Sattar Scott M Nelson Debbie A Lawlor Annette L Briley Paul T Seed Paul Welsh Lucilla Poston

Diabetologia 2017 10 1;60(10):1903-1912. Epub 2017 Aug 1.

Division of Women's Health, King's College London, 10th floor North Wing, St Thomas' Hospital, Westminster Bridge Road, London, SE1 7EH, UK.

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http://dx.doi.org/10.1007/s00125-017-4380-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6448883PMC
October 2017

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium.

Authors:
Gemma C Sharp Lucas A Salas Claire Monnereau Catherine Allard Paul Yousefi Todd M Everson Jon Bohlin Zongli Xu Rae-Chi Huang Sarah E Reese Cheng-Jian Xu Nour Baïz Cathrine Hoyo Golareh Agha Ritu Roy John W Holloway Akram Ghantous Simon K Merid Kelly M Bakulski Leanne K Küpers Hongmei Zhang Rebecca C Richmond Christian M Page Liesbeth Duijts Rolv T Lie Phillip E Melton Judith M Vonk Ellen A Nohr ClarLynda Williams-DeVane Karen Huen Sheryl L Rifas-Shiman Carlos Ruiz-Arenas Semira Gonseth Faisal I Rezwan Zdenko Herceg Sandra Ekström Lisa Croen Fahimeh Falahi Patrice Perron Margaret R Karagas Bilal M Quraishi Matthew Suderman Maria C Magnus Vincent W V Jaddoe Jack A Taylor Denise Anderson Shanshan Zhao Henriette A Smit Michele J Josey Asa Bradman Andrea A Baccarelli Mariona Bustamante Siri E Håberg Göran Pershagen Irva Hertz-Picciotto Craig Newschaffer Eva Corpeleijn Luigi Bouchard Debbie A Lawlor Rachel L Maguire Lisa F Barcellos George Davey Smith Brenda Eskenazi Wilfried Karmaus Carmen J Marsit Marie-France Hivert Harold Snieder M Daniele Fallin Erik Melén Monica C Munthe-Kaas Hasan Arshad Joseph L Wiemels Isabella Annesi-Maesano Martine Vrijheid Emily Oken Nina Holland Susan K Murphy Thorkild I A Sørensen Gerard H Koppelman John P Newnham Allen J Wilcox Wenche Nystad Stephanie J London Janine F Felix Caroline L Relton

Hum Mol Genet 2017 10;26(20):4067-4085

MRC Integrative Epidemiology Unit.

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http://dx.doi.org/10.1093/hmg/ddx290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5656174PMC
October 2017

Risk factor screening to identify women requiring oral glucose tolerance testing to diagnose gestational diabetes: A systematic review and meta-analysis and analysis of two pregnancy cohorts.

Authors:
Diane Farrar Mark Simmonds Maria Bryant Debbie A Lawlor Fidelma Dunne Derek Tuffnell Trevor A Sheldon

PLoS One 2017 6;12(4):e0175288. Epub 2017 Apr 6.

Department of Health Sciences, University of York, York, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0175288PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5383279PMC
September 2017

Prospective associations of psychosocial adversity in childhood with risk factors for cardiovascular disease in adulthood: the MRC National Survey of Health and Development.

Authors:
Emma L Anderson Rishi Caleyachetty Mai Stafford Diana Kuh Rebecca Hardy Debbie A Lawlor Abigail Fraser Laura D Howe

Int J Equity Health 2017 09 7;16(1):170. Epub 2017 Sep 7.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1186/s12939-017-0656-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590112PMC
September 2017

Adversity in childhood and measures of aging in midlife: Findings from a cohort of british women.

Authors:
Emma L Anderson Jon Heron Yoav Ben-Shlomo Diana Kuh Rachel Cooper Debbie A Lawlor Abigail Fraser Laura D Howe

Psychol Aging 2017 Sep;32(6):521-530

School of Social and Community Medicine, University of Bristol.

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http://dx.doi.org/10.1037/pag0000182DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592847PMC
September 2017

Associations between participation in organised physical activity in the school or community outside school hours and neighbourhood play with child physical activity and sedentary time: a cross-sectional analysis of primary school-aged children from the UK.

Authors:
Russell Jago Corrie Macdonald-Wallis Emma Solomon-Moore Janice L Thompson Debbie A Lawlor Simon J Sebire

BMJ Open 2017 Sep 14;7(9):e017588. Epub 2017 Sep 14.

Centre for Exercise, Nutrition and Health Sciences, School for Policy Studies, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1136/bmjopen-2017-017588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640140PMC
September 2017

Variants in the fetal genome near FLT1 are associated with risk of preeclampsia.

Authors:
Ralph McGinnis Valgerdur Steinthorsdottir Nicholas O Williams Gudmar Thorleifsson Scott Shooter Sigrun Hjartardottir Suzannah Bumpstead Lilja Stefansdottir Lucy Hildyard Jon K Sigurdsson John P Kemp Gabriela B Silva Liv Cecilie V Thomsen Tiina Jääskeläinen Eero Kajantie Sally Chappell Noor Kalsheker Ashley Moffett Susan Hiby Wai Kwong Lee Sandosh Padmanabhan Nigel A B Simpson Vivien A Dolby Eleonora Staines-Urias Stephanie M Engel Anita Haugan Lill Trogstad Gulnara Svyatova Nodira Zakhidova Dilbar Najmutdinova Anna F Dominiczak Håkon K Gjessing Juan P Casas Frank Dudbridge James J Walker Fiona Broughton Pipkin Unnur Thorsteinsdottir Reynir T Geirsson Debbie A Lawlor Ann-Charlotte Iversen Per Magnus Hannele Laivuori Kari Stefansson Linda Morgan

Nat Genet 2017 Aug 19;49(8):1255-1260. Epub 2017 Jun 19.

School of Life Sciences, University of Nottingham, Nottingham, UK.

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http://dx.doi.org/10.1038/ng.3895DOI Listing
August 2017

Low alcohol consumption and pregnancy and childhood outcomes: time to change guidelines indicating apparently 'safe' levels of alcohol during pregnancy? A systematic review and meta-analyses.

Authors:
Loubaba Mamluk Hannah B Edwards Jelena Savović Verity Leach Timothy Jones Theresa H M Moore Sharea Ijaz Sarah J Lewis Jenny L Donovan Debbie Lawlor George Davey Smith Abigail Fraser Luisa Zuccolo

BMJ Open 2017 Aug 3;7(7):e015410. Epub 2017 Aug 3.

MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1136/bmjopen-2016-015410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642770PMC
August 2017

Association of pre-pregnancy body mass index with offspring metabolic profile: Analyses of 3 European prospective birth cohorts.

Authors:
Diana L Santos Ferreira Dylan M Williams Antti J Kangas Pasi Soininen Mika Ala-Korpela George Davey Smith Marjo-Riitta Jarvelin Debbie A Lawlor

PLoS Med 2017 Aug 22;14(8):e1002376. Epub 2017 Aug 22.

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1002376DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5568725PMC
August 2017

Different strategies for diagnosing gestational diabetes to improve maternal and infant health.

Authors:
Diane Farrar Lelia Duley Therese Dowswell Debbie A Lawlor

Cochrane Database Syst Rev 2017 08 23;8:CD007122. Epub 2017 Aug 23.

Maternal and Child Health, Bradford Institute for Health Research, Bradford Royal Infirmary, Duckworth Lane, Bradford, UK, BD9 6RJ.

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http://dx.doi.org/10.1002/14651858.CD007122.pub4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483546PMC
August 2017

Early Antenatal Prediction of Gestational Diabetes in Obese Women: Development of Prediction Tools for Targeted Intervention.

Authors:
Sara L White Debbie A Lawlor Annette L Briley Keith M Godfrey Scott M Nelson Eugene Oteng-Ntim Stephen C Robson Naveed Sattar Paul T Seed Matias C Vieira Paul Welsh Melissa Whitworth Lucilla Poston Dharmintra Pasupathy

PLoS One 2016 8;11(12):e0167846. Epub 2016 Dec 8.

Division of Women's Health, King's College London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0167846PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5145208PMC
July 2017

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.

Authors:
Felix R Day Deborah J Thompson Hannes Helgason Daniel I Chasman Hilary Finucane Patrick Sulem Katherine S Ruth Sean Whalen Abhishek K Sarkar Eva Albrecht Elisabeth Altmaier Marzyeh Amini Caterina M Barbieri Thibaud Boutin Archie Campbell Ellen Demerath Ayush Giri Chunyan He Jouke J Hottenga Robert Karlsson Ivana Kolcic Po-Ru Loh Kathryn L Lunetta Massimo Mangino Brumat Marco George McMahon Sarah E Medland Ilja M Nolte Raymond Noordam Teresa Nutile Lavinia Paternoster Natalia Perjakova Eleonora Porcu Lynda M Rose Katharina E Schraut Ayellet V Segrè Albert V Smith Lisette Stolk Alexander Teumer Irene L Andrulis Stefania Bandinelli Matthias W Beckmann Javier Benitez Sven Bergmann Murielle Bochud Eric Boerwinkle Stig E Bojesen Manjeet K Bolla Judith S Brand Hiltrud Brauch Hermann Brenner Linda Broer Thomas Brüning Julie E Buring Harry Campbell Eulalia Catamo Stephen Chanock Georgia Chenevix-Trench Tanguy Corre Fergus J Couch Diana L Cousminer Angela Cox Laura Crisponi Kamila Czene George Davey Smith Eco J C N de Geus Renée de Mutsert Immaculata De Vivo Joe Dennis Peter Devilee Isabel Dos-Santos-Silva Alison M Dunning Johan G Eriksson Peter A Fasching Lindsay Fernández-Rhodes Luigi Ferrucci Dieter Flesch-Janys Lude Franke Marike Gabrielson Ilaria Gandin Graham G Giles Harald Grallert Daniel F Gudbjartsson Pascal Guénel Per Hall Emily Hallberg Ute Hamann Tamara B Harris Catharina A Hartman Gerardo Heiss Maartje J Hooning John L Hopper Frank Hu David J Hunter M Arfan Ikram Hae Kyung Im Marjo-Riitta Järvelin Peter K Joshi David Karasik Manolis Kellis Zoltan Kutalik Genevieve LaChance Diether Lambrechts Claudia Langenberg Lenore J Launer Joop S E Laven Stefania Lenarduzzi Jingmei Li Penelope A Lind Sara Lindstrom YongMei Liu Jian'an Luan Reedik Mägi Arto Mannermaa Hamdi Mbarek Mark I McCarthy Christa Meisinger Thomas Meitinger Cristina Menni Andres Metspalu Kyriaki Michailidou Lili Milani Roger L Milne Grant W Montgomery Anna M Mulligan Mike A Nalls Pau Navarro Heli Nevanlinna Dale R Nyholt Albertine J Oldehinkel Tracy A O'Mara Sandosh Padmanabhan Aarno Palotie Nancy Pedersen Annette Peters Julian Peto Paul D P Pharoah Anneli Pouta Paolo Radice Iffat Rahman Susan M Ring Antonietta Robino Frits R Rosendaal Igor Rudan Rico Rueedi Daniela Ruggiero Cinzia F Sala Marjanka K Schmidt Robert A Scott Mitul Shah Rossella Sorice Melissa C Southey Ulla Sovio Meir Stampfer Maristella Steri Konstantin Strauch Toshiko Tanaka Emmi Tikkanen Nicholas J Timpson Michela Traglia Thérèse Truong Jonathan P Tyrer André G Uitterlinden Digna R Velez Edwards Veronique Vitart Uwe Völker Peter Vollenweider Qin Wang Elisabeth Widen Ko Willems van Dijk Gonneke Willemsen Robert Winqvist Bruce H R Wolffenbuttel Jing Hua Zhao Magdalena Zoledziewska Marek Zygmunt Behrooz Z Alizadeh Dorret I Boomsma Marina Ciullo Francesco Cucca Tõnu Esko Nora Franceschini Christian Gieger Vilmundur Gudnason Caroline Hayward Peter Kraft Debbie A Lawlor Patrik K E Magnusson Nicholas G Martin Dennis O Mook-Kanamori Ellen A Nohr Ozren Polasek David Porteous Alkes L Price Paul M Ridker Harold Snieder Tim D Spector Doris Stöckl Daniela Toniolo Sheila Ulivi Jenny A Visser Henry Völzke Nicholas J Wareham James F Wilson Amanda B Spurdle Unnur Thorsteindottir Katherine S Pollard Douglas F Easton Joyce Y Tung Jenny Chang-Claude David Hinds Anna Murray Joanne M Murabito Kari Stefansson Ken K Ong John R B Perry

Nat Genet 2017 Jun 24;49(6):834-841. Epub 2017 Apr 24.

MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.3841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841952PMC
June 2017

Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.

Authors:
Caroline E Dale Ghazaleh Fatemifar Tom M Palmer Jon White David Prieto-Merino Delilah Zabaneh Jorgen E L Engmann Tina Shah Andrew Wong Helen R Warren Stela McLachlan Stella Trompet Max Moldovan Richard W Morris Reecha Sofat Meena Kumari Elina Hyppönen Barbara J Jefferis Tom R Gaunt Yoav Ben-Shlomo Ang Zhou Aleksandra Gentry-Maharaj Andy Ryan Renée de Mutsert Raymond Noordam Mark J Caulfield J Wouter Jukema Bradford B Worrall Patricia B Munroe Usha Menon Chris Power Diana Kuh Debbie A Lawlor Steve E Humphries Dennis O Mook-Kanamori Naveed Sattar Mika Kivimaki Jacqueline F Price George Davey Smith Frank Dudbridge Aroon D Hingorani Michael V Holmes Juan P Casas

Circulation 2017 Jun 12;135(24):2373-2388. Epub 2017 May 12.

From Farr Institute of Health Informatics Research, UCL Institute of Health Informatics, University College London, United Kingdom (C.E.D., G.F., D.P.-M., A.D.H., J.P.C.); Department of Mathematics and Statistics, Lancaster University, United Kingdom (T.M.P.); UCLGenetics Institute, University College London, United Kingdom (J.W.); Applied Statistical Methods in Medical Research Group, Universidad Catolica de San Antonio de Murcia, Spain (D.P.-M.); Social Genetic & Developmental Psychiatry, King's College London, United Kingdom (D.Z.); Institute of Cardiovascular Science, University College London, United Kingdom (J.E.L.E., T.S., A.D.H., S.E.H.); MRC Unit for Lifelong Health & Ageing at UCL, London, United Kingdom (A.W., D.K.); Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom (H.R.W., M.J.C., P.B.M.); NIHR Barts Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom (H.R.W., M.J.C., P.B.M.); Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, United Kingdom (S.M., J.F.P.); Department of Cardiology, Leiden University Medical Center, The Netherlands (S.T., W.J.); South Australian Health and Medical Research Institute, Adelaide (M.M., E.H.); EMBL Australia, Adelaide (M.M.); School of Social and Community Medicine, University of Bristol, United Kingdom (R.W.M., T.R.G., Y.B.-S., D.A.L., G.D.S.); Centre for Clinical Pharmacology, University College London, United Kingdom (R.S.); Institute for Social and Economic Research, University of Essex, Colchester, United Kingdom (M.K.); Centre for Population Health Research, School of Health Sciences and Sansom Institute, University of South Australia, Adelaide (E.H., A.Z.); Population, Policy & Practice, UCL Great Ormond Street Institute of Child Health, London, United Kingdom (E.H., C.P.); Department of Primary Care & Population Health, University College London, Royal Free Campus, United Kingdom (B.J.J.); MRC Integrative Epidemiology Unit, University of Bristol, United Kingdom (T.R.G., D.A.L., G.D.S.); Department of Women's Cancer, Institute for Women's Health, UCL, London, United Kingdom (A.G.-M., A.R., U.M.); Department of Clinical Epidemiology, Leiden University Medical Center, The Netherlands (R.d.M., D.O.M.-K.); Department of Internal Medicine, Section Gerontology and Geriatrics, Leiden University Medical Center, The Netherlands (R.N., S.T.); Interuniversity Cardiology Institute Netherlands, Utrecht (W.J.); Departments of Neurology and Public Health Sciences, University of Virginia, Charlottesville (B.B.W.); Department of Public Health and Primary Care, Leiden University Medical Center, The Netherlands (D.O.M.-K.); BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, United Kingdom (N.S.); Department of Epidemiology and Public Health, University College London, United Kingdom (M.K.); Department of Non-communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, United Kingdom (F.D.); Department of Health Sciences, University of Leicester, United Kingdom (F.D.); Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, Big Data Institute Building, University of Oxford, United Kingdom (M.V.H.); Medical Research Council Population Health Research Unit at the University of Oxford, United Kingdom (M.V.H.); and National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals, United Kingdom (M.V.H.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.026560DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515354PMC
June 2017

Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study.

Authors:
Alastair J Noyce Demis A Kia Gibran Hemani Aude Nicolas T Ryan Price Eduardo De Pablo-Fernandez Philip C Haycock Patrick A Lewis Thomas Foltynie George Davey Smith Anette Schrag Andrew J Lees John Hardy Andrew Singleton Mike A Nalls Neil Pearce Debbie A Lawlor Nicholas W Wood

PLoS Med 2017 Jun 13;14(6):e1002314. Epub 2017 Jun 13.

Department of Molecular Neuroscience, UCL Institute of Neurology, University College London, London, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1002314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5469450PMC
June 2017

Treatments for gestational diabetes: a systematic review and meta-analysis.

Authors:
Diane Farrar Mark Simmonds Maria Bryant Trevor A Sheldon Derek Tuffnell Su Golder Debbie A Lawlor

BMJ Open 2017 06 24;7(6):e015557. Epub 2017 Jun 24.

MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1136/bmjopen-2016-015557DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5734427PMC
June 2017

Screening for familial hypercholesterolaemia in childhood: Avon Longitudinal Study of Parents and Children (ALSPAC).

Authors:
Marta Futema Jackie A Cooper Marietta Charakida Christopher Boustred Naveed Sattar John Deanfield Debbie A Lawlor Nicholas J Timpson Steve E Humphries Aroon D Hingorani

Atherosclerosis 2017 05 8;260:47-55. Epub 2017 Mar 8.

Genetic Epidemiology Group, Institute of Cardiovascular Science, Farr Institute for Health Informatics, University College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5414415PMC
May 2017

Are parents' motivations to exercise and intention to engage in regular family-based activity associated with both adult and child physical activity?

Authors:
Emma Solomon-Moore Simon J Sebire Janice L Thompson Jesmond Zahra Debbie A Lawlor Russ Jago

BMJ Open Sport Exerc Med 2016 12;2(1):e000137. Epub 2017 Feb 12.

Centre for Exercise, Nutrition and Health Sciences, School for Policy Studies, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1136/bmjsem-2016-000137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569264PMC
February 2017

Using Genetic Variation to Explore the Causal Effect of Maternal Pregnancy Adiposity on Future Offspring Adiposity: A Mendelian Randomisation Study.

Authors:
Rebecca C Richmond Nicholas J Timpson Janine F Felix Tom Palmer Romy Gaillard George McMahon George Davey Smith Vincent W Jaddoe Debbie A Lawlor

PLoS Med 2017 01 24;14(1):e1002221. Epub 2017 Jan 24.

MRC Integrative Epidemiology Unit, University of Bristol, Bristol, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1002221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5261553PMC
January 2017

Customised and Noncustomised Birth Weight Centiles and Prediction of Stillbirth and Infant Mortality and Morbidity: A Cohort Study of 979,912 Term Singleton Pregnancies in Scotland.

Authors:
Stamatina Iliodromiti Daniel F Mackay Gordon C S Smith Jill P Pell Naveed Sattar Debbie A Lawlor Scott M Nelson

PLoS Med 2017 Jan 31;14(1):e1002228. Epub 2017 Jan 31.

School of Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow, United Kingdom.

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http://dx.doi.org/10.1371/journal.pmed.1002228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283655PMC
January 2017

Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence.

Authors:
Qin Wang Peter Würtz Kirsi Auro Ville-Petteri Mäkinen Antti J Kangas Pasi Soininen Mika Tiainen Tuulia Tynkkynen Jari Jokelainen Kristiina Santalahti Marko Salmi Stefan Blankenberg Tanja Zeller Jorma Viikari Mika Kähönen Terho Lehtimäki Veikko Salomaa Markus Perola Sirpa Jalkanen Marjo-Riitta Järvelin Olli T Raitakari Johannes Kettunen Debbie A Lawlor Mika Ala-Korpela

BMC Med 2016 Dec 13;14(1):205. Epub 2016 Dec 13.

Computational Medicine, Faculty of Medicine, University of Oulu and Biocenter Oulu, Oulu, Finland.

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http://dx.doi.org/10.1186/s12916-016-0733-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153817PMC
December 2016

Triangulation in aetiological epidemiology.

Authors:
Debbie A Lawlor Kate Tilling George Davey Smith

Int J Epidemiol 2016 12;45(6):1866-1886

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.

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https://academic.oup.com/ije/article-lookup/doi/10.1093/ije/
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http://dx.doi.org/10.1093/ije/dyw314DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841843PMC
December 2016

Causal inference-so much more than statistics.

Authors:
Neil Pearce Debbie A Lawlor

Int J Epidemiol 2016 12;45(6):1895-1903

MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1093/ije/dyw328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5841844PMC
December 2016

Long-term effects of the Active for Life Year 5 (AFLY5) school-based cluster-randomised controlled trial.

Authors:
Emma L Anderson Laura D Howe Ruth R Kipping Rona Campbell Russell Jago Sian M Noble Sian Wells Catherine Chittleborough Tim J Peters Debbie A Lawlor

BMJ Open 2016 11 24;6(11):e010957. Epub 2016 Nov 24.

School of Social and Community Medicine, University of Bristol, Bristol, UK.

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http://dx.doi.org/10.1136/bmjopen-2015-010957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168509PMC
November 2016

The identification and treatment of women with hyperglycaemia in pregnancy: an analysis of individual participant data, systematic reviews, meta-analyses and an economic evaluation.

Authors:
Diane Farrar Mark Simmonds Susan Griffin Ana Duarte Debbie A Lawlor Mark Sculpher Lesley Fairley Su Golder Derek Tuffnell Martin Bland Fidelma Dunne Donald Whitelaw John Wright Trevor A Sheldon

Health Technol Assess 2016 11;20(86):1-348

Hull York Medical School, University of York, York, UK.

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http://dx.doi.org/10.3310/hta20860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5165282PMC
November 2016

Metabolic signatures of birthweight in 18 288 adolescents and adults.

Authors:
Peter Würtz Qin Wang Marjo Niironen Tuulia Tynkkynen Mika Tiainen Fotios Drenos Antti J Kangas Pasi Soininen Michael R Skilton Kauko Heikkilä Anneli Pouta Mika Kähönen Terho Lehtimäki Richard J Rose Eero Kajantie Markus Perola Jaakko Kaprio Johan G Eriksson Olli T Raitakari Debbie A Lawlor George Davey Smith Marjo-Riitta Järvelin Mika Ala-Korpela Kirsi Auro

Int J Epidemiol 2016 10;45(5):1539-1550

Department of Genomics and Biomarkers, National Institute for Health and Welfare, Helsinki, Finland.

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http://dx.doi.org/10.1093/ije/dyw255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100627PMC
October 2016