Publications by authors named "Debbie L Cunningham"

15Publications

Combined transcriptomic and phosphoproteomic analysis of BMP4 signaling in human embryonic stem cells.

Authors:
Angelos Papadopoulos Varvara Chalmantzi Olga Mikhaylichenko Marko Hyvönen Dimitris Stellas Aditi Kanhere John Heath Debbie L Cunningham Theodore Fotsis Carol Murphy

Stem Cell Res 2020 Dec 18;50:102133. Epub 2020 Dec 18.

School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom; Department of Biomedical Research, Institute of Molecular Biology and Biotechnology, Foundation of Research and Technology-Hellas, University Campus of Ioannina, 45110 Ioannina, Greece. Electronic address:

View Article and Find Full Text PDF
December 2020

Differential responses to kinase inhibition in FGFR2-addicted triple negative breast cancer cells: a quantitative phosphoproteomics study.

Authors:
Debbie L Cunningham Adil R Sarhan Andrew J Creese Katherine P B Larkins Hongyan Zhao Harriet R Ferguson Katie Brookes Anna A Marusiak Helen J Cooper John K Heath

Sci Rep 2020 05 14;10(1):7950. Epub 2020 May 14.

School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.

View Article and Find Full Text PDF
May 2020

Vomocytosis of live pathogens from macrophages is regulated by the atypical MAP kinase ERK5.

Authors:
Andrew S Gilbert Paula I Seoane Poppy Sephton-Clark Aleksandra Bojarczuk Richard Hotham Emanuele Giurisato Adil R Sarhan Amy Hillen Greetje Vande Velde Nathanael S Gray Dario R Alessi Debbie L Cunningham Cathy Tournier Simon A Johnston Robin C May

Sci Adv 2017 08 16;3(8):e1700898. Epub 2017 Aug 16.

Institute of Microbiology and Infection, School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

View Article and Find Full Text PDF
August 2017

Quantitative Phosphoproteomics Reveals a Role for Collapsin Response Mediator Protein 2 in PDGF-Induced Cell Migration.

Authors:
Adil R Sarhan Justyna Szyroka Shabana Begum Michael G Tomlinson Neil A Hotchin John K Heath Debbie L Cunningham

Sci Rep 2017 06 21;7(1):3970. Epub 2017 Jun 21.

School of Biosciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.

View Article and Find Full Text PDF
June 2017

LAR protein tyrosine phosphatase regulates focal adhesions through CDK1.

Authors:
Adil R Sarhan Trushar R Patel Alana R Cowell Michael G Tomlinson Carina Hellberg John K Heath Debbie L Cunningham Neil A Hotchin

J Cell Sci 2016 08 27;129(15):2962-71. Epub 2016 Jun 27.

School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK

View Article and Find Full Text PDF
August 2016

Regulation of Platelet Derived Growth Factor Signaling by Leukocyte Common Antigen-related (LAR) Protein Tyrosine Phosphatase: A Quantitative Phosphoproteomics Study.

Authors:
Adil R Sarhan Trushar R Patel Andrew J Creese Michael G Tomlinson Carina Hellberg John K Heath Neil A Hotchin Debbie L Cunningham

Mol Cell Proteomics 2016 06 13;15(6):1823-36. Epub 2016 Apr 13.

‡From the School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom

View Article and Find Full Text PDF
June 2016

FAIMS and Phosphoproteomics of Fibroblast Growth Factor Signaling: Enhanced Identification of Multiply Phosphorylated Peptides.

Authors:
Hongyan Zhao Debbie L Cunningham Andrew J Creese John K Heath Helen J Cooper

J Proteome Res 2015 Dec 5;14(12):5077-87. Epub 2015 Nov 5.

School of Biosciences, University of Birmingham , Edgbaston, Birmingham B15 2TT, United Kingdom.

View Article and Find Full Text PDF
December 2015

Eps8 controls Src- and FAK-dependent phenotypes in squamous carcinoma cells.

Authors:
Christina Schoenherr Bryan Serrels Charlotte Proby Debbie L Cunningham Jane E Findlay George S Baillie John K Heath Margaret C Frame

J Cell Sci 2014 Dec 29;127(Pt 24):5303-16. Epub 2014 Oct 29.

Edinburgh Cancer Research Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Crewe Road South, EH4 2XR Edinburgh, UK

View Article and Find Full Text PDF
December 2014

The non-receptor tyrosine kinase Ack1 regulates the fate of activated EGFR by inducing trafficking to the p62/NBR1 pre-autophagosome.

Authors:
Sylwia Jones Debbie L Cunningham Joshua Z Rappoport John K Heath

J Cell Sci 2014 Mar 10;127(Pt 5):994-1006. Epub 2014 Jan 10.

School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK.

View Article and Find Full Text PDF
March 2014

Novel binding partners and differentially regulated phosphorylation sites clarify Eps8 as a multi-functional adaptor.

Authors:
Debbie L Cunningham Andrew J Creese Giulio Auciello Steve M M Sweet Tulin Tatar Joshua Z Rappoport Melissa M Grant John K Heath

PLoS One 2013 23;8(4):e61513. Epub 2013 Apr 23.

Cancer Research UK Growth Factor Signalling Group, School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, United Kingdom.

View Article and Find Full Text PDF
November 2013

Regulation of fibroblast growth factor receptor signalling and trafficking by Src and Eps8.

Authors:
Giulio Auciello Debbie L Cunningham Tulin Tatar John K Heath Joshua Z Rappoport

J Cell Sci 2013 Jan 30;126(Pt 2):613-24. Epub 2012 Nov 30.

CRUK Growth Factor Group, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK.

View Article and Find Full Text PDF
January 2013

Differential phosphoproteomics of fibroblast growth factor signaling: identification of Src family kinase-mediated phosphorylation events.

Authors:
Debbie L Cunningham Steve M M Sweet Helen J Cooper John K Heath

J Proteome Res 2010 May;9(5):2317-28

School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, United Kingdom.

View Article and Find Full Text PDF
May 2010

Database search strategies for proteomic data sets generated by electron capture dissociation mass spectrometry.

Authors:
Steve M M Sweet Andrew W Jones Debbie L Cunningham John K Heath Andrew J Creese Helen J Cooper

J Proteome Res 2009 Dec;8(12):5475-84

School of Biosciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.

View Article and Find Full Text PDF
December 2009

SLoMo: automated site localization of modifications from ETD/ECD mass spectra.

Authors:
Christopher M Bailey Steve M M Sweet Debbie L Cunningham Martin Zeller John K Heath Helen J Cooper

J Proteome Res 2009 Apr;8(4):1965-71

School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.

View Article and Find Full Text PDF
April 2009

Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.

Authors:
Steve M M Sweet Christopher M Bailey Debbie L Cunningham John K Heath Helen J Cooper

Mol Cell Proteomics 2009 May 8;8(5):904-12. Epub 2009 Jan 8.

Cancer Research UK Growth Factor Group, College of Life and Environmental Sciences, Universityof Birmingham, Edgbaston, Birmingham B152TT, United Kingdom.

View Article and Find Full Text PDF
May 2009