Debabrata Mukhopadhyay

Debabrata Mukhopadhyay

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Debabrata Mukhopadhyay

Debabrata Mukhopadhyay

Publications by authors named "Debabrata Mukhopadhyay"

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Nanomechanical insights: Amyloid beta oligomer-induced senescent brain endothelial cells.

Biochim Biophys Acta Biomembr 2019 Dec 9;1861(12):183061. Epub 2019 Sep 9.

Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Jacksonville, FL, USA; Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Jacksonville, FL, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00052736193020
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http://dx.doi.org/10.1016/j.bbamem.2019.183061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791778PMC
December 2019

Development of multi-drug loaded PEGylated nanodiamonds to inhibit tumor growth and metastasis in genetically engineered mouse models of pancreatic cancer.

Nanoscale 2019 Nov 11. Epub 2019 Nov 11.

Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Jacksonville, FL 32224, USA. and Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine and Science, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.1039/c9nr05478bDOI Listing
November 2019

DNA-SWCNT Biosensors Allow Real-Time Monitoring of Therapeutic Responses in Pancreatic Ductal Adenocarcinoma.

Cancer Res 2019 Sep 10;79(17):4515-4523. Epub 2019 Jul 10.

Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Jacksonville, Florida.

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http://dx.doi.org/10.1158/0008-5472.CAN-18-3337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726513PMC
September 2019

Co-delivery of everolimus and vinorelbine via a tumor-targeted liposomal formulation inhibits tumor growth and metastasis in RCC.

Int J Nanomedicine 2019 11;14:5109-5123. Epub 2019 Jul 11.

Department of Biochemistry and Molecular Biology, Mayo Clinic Florida, Jacksonville, FL 32224, USA.

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http://dx.doi.org/10.2147/IJN.S204221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6636461PMC
September 2019

Divergent roles of Plexin D1 in cancer.

Biochim Biophys Acta Rev Cancer 2019 08 30;1872(1):103-110. Epub 2019 May 30.

Department of Biochemistry and Molecular Biology, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2019.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692237PMC
August 2019

Tumor selective uptake of drug-nanodiamond complexes improves therapeutic outcome in pancreatic cancer.

Nanomedicine 2019 06 6;18:112-121. Epub 2019 Mar 6.

Division of Molecular Toxicology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.nano.2019.02.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6588439PMC
June 2019

AFM study: Cell cycle and probe geometry influences nanomechanical characterization of Panc1 cells.

Biochim Biophys Acta Gen Subj 2019 May 11;1863(5):802-812. Epub 2019 Feb 11.

Department of Biochemistry and Molecular Biology, Mayo Clinic, Jacksonville, FL, USA; Department of Pathology and Biomedical Engineering, Mayo Clinic, Jacksonville, FL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2019.02.006DOI Listing
May 2019

Genetic status of KRAS influences Transforming Growth Factor-beta (TGF-β) signaling: An insight into Neuropilin-1 (NRP1) mediated tumorigenesis.

Semin Cancer Biol 2019 02 2;54:72-79. Epub 2018 Feb 2.

Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Jacksonville, FL, United States. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2018.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6072630PMC
February 2019

Genetic status of KRAS modulates the role of Neuropilin-1 in tumorigenesis.

Sci Rep 2017 10 10;7(1):12877. Epub 2017 Oct 10.

Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Sciences, Rochester, MN, USA.

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http://dx.doi.org/10.1038/s41598-017-12992-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635066PMC
October 2017

CorMatrix Wrapped Around the Adventitia of the Arteriovenous Fistula Outflow Vein Attenuates Venous Neointimal Hyperplasia.

Sci Rep 2017 10 30;7(1):14298. Epub 2017 Oct 30.

Vascular and Interventional Radiology Translational Laboratory, Department of Radiology, Rochester, Minnesota, USA.

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http://dx.doi.org/10.1038/s41598-017-14696-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5662725PMC
October 2017

Preclinical efficacy of the novel competitive NAMPT inhibitor STF-118804 in pancreatic cancer.

Oncotarget 2017 Oct 29;8(49):85054-85067. Epub 2017 Jun 29.

Laboratory of Signal Transduction and Molecular Nutrition, Department of Anesthesiology, Mayo Clinic College of Medicine, Rochester, MN, U.S.A.

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http://dx.doi.org/10.18632/oncotarget.18841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689593PMC
October 2017

Exosomes and their role in the micro-/macro-environment: a comprehensive review.

J Biomed Res 2017 Sep;31(5):386-394

Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN 55905, USA.

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http://dx.doi.org/10.7555/JBR.30.20150162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5706431PMC
September 2017

Mixed poly(vinyl pyrrolidone)-based drug-loaded nanomicelles shows enhanced efficacy against pancreatic cancer cell lines.

Eur J Pharm Sci 2017 May 18;102:250-260. Epub 2017 Mar 18.

Centre for Biomedical and Biomaterials Research (CBBR), University of Mauritius, MSIRI Building, Réduit, Mauritius. Electronic address:

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http://dx.doi.org/10.1016/j.ejps.2017.03.021DOI Listing
May 2017

Quantification of lipid modified estrogenic derivative (ESC8) in rat plasma by LC-MS: application to a pharmacokinetic study.

Biomed Chromatogr 2016 Dec 24;30(12):2024-2030. Epub 2016 Jul 24.

Department of Clinical Pharmacy, King Saud University, Riyadh, Saudi Arabia.

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http://dx.doi.org/10.1002/bmc.3780DOI Listing
December 2016

Tracking and Therapeutic Value of Human Adipose Tissue-derived Mesenchymal Stem Cell Transplantation in Reducing Venous Neointimal Hyperplasia Associated with Arteriovenous Fistula.

Radiology 2016 May 19;279(2):513-22. Epub 2015 Nov 19.

From the Vascular and Interventional Radiology Translational Laboratory, Department of Radiology (B.Y., A. Brahmbhatt, E.N.T., B.T., D.L.M., S.E., A. Bansal, M.K.P., T.R.D., S.M.), and Department of Biochemistry and Molecular Biology (A.B.D., E.B.L., D.M., S.M.), Mayo Clinic, 200 First St SW, Rochester, MN 55905.

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http://dx.doi.org/10.1148/radiol.2015150947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4836988PMC
May 2016

Selective mode of action of plumbagin through BRCA1 deficient breast cancer stem cells.

BMC Cancer 2016 05 26;16:336. Epub 2016 May 26.

Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Thiruvananthapuram, Kerala, 695014, India.

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http://dx.doi.org/10.1186/s12885-016-2372-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4882782PMC
May 2016

The Role of Repeat Administration of Adventitial Delivery of Lentivirus-shRNA-Vegf-A in Arteriovenous Fistula to Prevent Venous Stenosis Formation.

J Vasc Interv Radiol 2016 Apr 2;27(4):576-83. Epub 2016 Mar 2.

Amity Institute of Public Health, Amity University Uttar Pradesh, Noida, Uttar Pradesh, India; Vascular and Interventional Radiology Translational Laboratory Mayo Clinic, 200 First Street SW, Rochester, MN 55905; Department of Radiology, and Department of Biochemistry and Molecular Biology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905. Electronic address:

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http://dx.doi.org/10.1016/j.jvir.2015.12.751DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808445PMC
April 2016

Development of Liposomal Formulation for Delivering Anticancer Drug to Breast Cancer Stem-Cell-Like Cells and its Pharmacokinetics in an Animal Model.

Mol Pharm 2016 Mar 10;13(3):1081-8. Epub 2016 Feb 10.

Department of Clinical Pharmacy, College of Pharmacy, King Saud University , Riyadh 11451, Saudi Arabia.

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http://dx.doi.org/10.1021/acs.molpharmaceut.5b00900DOI Listing
March 2016

Genomic analyses identify molecular subtypes of pancreatic cancer.

Authors:
Peter Bailey David K Chang Katia Nones Amber L Johns Ann-Marie Patch Marie-Claude Gingras David K Miller Angelika N Christ Tim J C Bruxner Michael C Quinn Craig Nourse L Charles Murtaugh Ivon Harliwong Senel Idrisoglu Suzanne Manning Ehsan Nourbakhsh Shivangi Wani Lynn Fink Oliver Holmes Venessa Chin Matthew J Anderson Stephen Kazakoff Conrad Leonard Felicity Newell Nick Waddell Scott Wood Qinying Xu Peter J Wilson Nicole Cloonan Karin S Kassahn Darrin Taylor Kelly Quek Alan Robertson Lorena Pantano Laura Mincarelli Luis N Sanchez Lisa Evers Jianmin Wu Mark Pinese Mark J Cowley Marc D Jones Emily K Colvin Adnan M Nagrial Emily S Humphrey Lorraine A Chantrill Amanda Mawson Jeremy Humphris Angela Chou Marina Pajic Christopher J Scarlett Andreia V Pinho Marc Giry-Laterriere Ilse Rooman Jaswinder S Samra James G Kench Jessica A Lovell Neil D Merrett Christopher W Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Kim Moran-Jones Nigel B Jamieson Janet S Graham Fraser Duthie Karin Oien Jane Hair Robert Grützmann Anirban Maitra Christine A Iacobuzio-Donahue Christopher L Wolfgang Richard A Morgan Rita T Lawlor Vincenzo Corbo Claudio Bassi Borislav Rusev Paola Capelli Roberto Salvia Giampaolo Tortora Debabrata Mukhopadhyay Gloria M Petersen Donna M Munzy William E Fisher Saadia A Karim James R Eshleman Ralph H Hruban Christian Pilarsky Jennifer P Morton Owen J Sansom Aldo Scarpa Elizabeth A Musgrove Ulla-Maja Hagbo Bailey Oliver Hofmann Robert L Sutherland David A Wheeler Anthony J Gill Richard A Gibbs John V Pearson Nicola Waddell Andrew V Biankin Sean M Grimmond

Nature 2016 Mar 24;531(7592):47-52. Epub 2016 Feb 24.

Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1038/nature16965DOI Listing
March 2016

The role of Iex-1 in the pathogenesis of venous neointimal hyperplasia associated with hemodialysis arteriovenous fistula.

PLoS One 2014 18;9(7):e102542. Epub 2014 Jul 18.

Vascular and Interventional Radiology Translational Laboratory, Department of Radiology, University of Cincinnati, Cincinnati, Ohio, United States of America; Department of Biochemistry and Molecular Biology, Department of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102542PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103828PMC
November 2015

Cardiomyopathy and Worsened Ischemic Heart Failure in SM22-α Cre-Mediated Neuropilin-1 Null Mice: Dysregulation of PGC1α and Mitochondrial Homeostasis.

Arterioscler Thromb Vasc Biol 2015 Jun 16;35(6):1401-12. Epub 2015 Apr 16.

From the Department of Biochemistry and Molecular Biology (Y.W., Y.C., S.B., A.K.S., E.W., L.H.H., S.K.D., E.B.L., D.M.), Center for Regenerative Medicine, Marriott Heart Disease Research Program, Division of Cardiovascular Diseases, Departments of Medicine, Molecular Pharmacology and Experimental Therapeutics, and Medical Genetics (S.Y., A.T.), Department of Anesthesiology (V.N., J.C.-P., E.N.C.), Department of Health Sciences Research, Division of Biomedical Statistics and Informatics, Health Science Program (K.S., J.-P.A.K.), Department of Gastroenterology (V.S.), and Thoracic Diseases Research Unit, Department of Biochemistry and Molecular Biology (E.B.L.), Mayo Clinic, Rochester, MN; Molecular Cardiology and Angiogenesis Laboratory, Department of Surgery (M.T., M.J., M.T.R., J.A.S., N.M.) and Department of Cell Biology, Center for Vascular Biology (K.P.C.), University of Connecticut Health Center, Farmington; Department of Surgery, Saint Mary's Hospital, Waterbury, CT (M.J., M.T.R., J.A.S.); and Yale Cardiovascular Research Center, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT (M.S.).

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http://dx.doi.org/10.1161/ATVBAHA.115.305566DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441604PMC
June 2015

Metformin suppresses pancreatic tumor growth with inhibition of NFκB/STAT3 inflammatory signaling.

Pancreas 2015 May;44(4):636-47

From the *Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic, Rochester, MN; †Rutgers Cancer Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick; ‡Department of Epidemiology, School of Public Health, Rutgers, The State University of New Jersey, Piscataway, NJ; and §Department of Biochemistry and Molecular Biology, ∥Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, and ¶Division of Anatomic Pathology, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1097/MPA.0000000000000308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399019PMC
May 2015

Blood outgrowth endothelial cells reduce hypoxia-mediated fibroblast to myofibroblast conversion by decreasing proangiogenic cytokines.

J Vasc Res 2014 7;51(6):458-67. Epub 2015 Feb 7.

Vascular and Interventional Radiology Translational Laboratory, Department of Radiology, Mayo Clinic, Rochester, Minn., USA.

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http://dx.doi.org/10.1159/000369929DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4376323PMC
March 2015

Adventitial delivery of lentivirus-shRNA-ADAMTS-1 reduces venous stenosis formation in arteriovenous fistula.

PLoS One 2014 14;9(4):e94510. Epub 2014 Apr 14.

Vascular and Interventional Radiology Translational Laboratory, Department of Radiology, Mayo Clinic, Rochester, Minnesota, United States of America; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094510PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986087PMC
January 2015

The role of factor inhibiting HIF (FIH-1) in inhibiting HIF-1 transcriptional activity in glioblastoma multiforme.

PLoS One 2014 23;9(1):e86102. Epub 2014 Jan 23.

Department of Biomedical Science, Mercer University School of Medicine, Savannah, Georgia, United States of America ; Department of Obstetrics and Gynecology, Memorial Health Hospital, Savannah, Georgia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0086102PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900478PMC
November 2014

Identification of a new class of MDM2 inhibitor that inhibits growth of orthotopic pancreatic tumors in mice.

Gastroenterology 2014 Oct 10;147(4):893-902.e2. Epub 2014 Jul 10.

Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas; Cancer Biology Center, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, Texas. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2014.07.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170027PMC
October 2014

Non-metastatic 2 (NME2)-mediated suppression of lung cancer metastasis involves transcriptional regulation of key cell adhesion factor vinculin.

Nucleic Acids Res 2014 Oct 23;42(18):11589-600. Epub 2014 Sep 23.

Proteomics and Structural Biology Unit, Institute of Genomics and Integrative Biology, CSIR, Mall Road, Delhi 110 007, India G.N.R. Knowledge Centre for Genome Informatics, Institute of Genomics and Integrative Biology, CSIR, Mall Road, Delhi 110 007, India Academy of Scientific and Innovative Research (AcSIR), New Delhi, India

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http://dx.doi.org/10.1093/nar/gku860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4191424PMC
October 2014

Selective assembly of DNA-conjugated single-walled carbon nanotubes from the vascular secretome.

ACS Nano 2014 Sep 3;8(9):9126-36. Epub 2014 Sep 3.

Department of Physiology and Biomedical Engineering and ‡Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine , Rochester, Minnesota 55904, United States.

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http://dx.doi.org/10.1021/nn5026912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174097PMC
September 2014

Spatiotemporal intracellular nitric oxide signaling captured using internalized, near-infrared fluorescent carbon nanotube nanosensors.

Nano Lett 2014 Aug 30;14(8):4887-94. Epub 2014 Jul 30.

Department of Chemical Engineering, Massachusetts Institute of Technology , Cambridge, Massachusetts 02139, United States.

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http://dx.doi.org/10.1021/nl502338yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134139PMC
August 2014

Vascular endothelial growth factor promotes fibrosis resolution and repair in mice.

Gastroenterology 2014 May 4;146(5):1339-50.e1. Epub 2014 Feb 4.

Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2014.01.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4001704PMC
May 2014

Adventitial transduction of lentivirus-shRNA-VEGF-A in arteriovenous fistula reduces venous stenosis formation.

Kidney Int 2014 Feb 7;85(2):289-306. Epub 2013 Aug 7.

1] Vascular and Interventional Radiology Translational Laboratory, Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA [2] Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA.

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http://www.biomedsearch.com/attachments/00/23/92/49/23924957
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http://linkinghub.elsevier.com/retrieve/pii/S008525381556183
Publisher Site
http://dx.doi.org/10.1038/ki.2013.290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3844094PMC
February 2014

Inhibition of GSK-3 induces differentiation and impaired glucose metabolism in renal cancer.

Mol Cancer Ther 2014 Feb 10;13(2):285-96. Epub 2013 Dec 10.

Corresponding Author: Debabrata Mukhopadhyay, Mayo Clinic College of Medicine, 200 First Street SW, Guggenheim 1321C, Rochester, MN 55905.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0681DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956125PMC
February 2014

Simvastatin reduces venous stenosis formation in a murine hemodialysis vascular access model.

Kidney Int 2013 Aug 1;84(2):338-52. Epub 2013 May 1.

Department of Radiology, Vascular and Interventional Radiology Translational Laboratory, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1038/ki.2013.112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731558PMC
August 2013

New insights into pancreatic cancer-induced paraneoplastic diabetes.

Nat Rev Gastroenterol Hepatol 2013 Jul 26;10(7):423-33. Epub 2013 Mar 26.

Department of Internal Medicine, Mayo Clinic, 200 First Street South West, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1038/nrgastro.2013.49DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3932322PMC
July 2013

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes.

Authors:
Andrew V Biankin Nicola Waddell Karin S Kassahn Marie-Claude Gingras Lakshmi B Muthuswamy Amber L Johns David K Miller Peter J Wilson Ann-Marie Patch Jianmin Wu David K Chang Mark J Cowley Brooke B Gardiner Sarah Song Ivon Harliwong Senel Idrisoglu Craig Nourse Ehsan Nourbakhsh Suzanne Manning Shivangi Wani Milena Gongora Marina Pajic Christopher J Scarlett Anthony J Gill Andreia V Pinho Ilse Rooman Matthew Anderson Oliver Holmes Conrad Leonard Darrin Taylor Scott Wood Qinying Xu Katia Nones J Lynn Fink Angelika Christ Tim Bruxner Nicole Cloonan Gabriel Kolle Felicity Newell Mark Pinese R Scott Mead Jeremy L Humphris Warren Kaplan Marc D Jones Emily K Colvin Adnan M Nagrial Emily S Humphrey Angela Chou Venessa T Chin Lorraine A Chantrill Amanda Mawson Jaswinder S Samra James G Kench Jessica A Lovell Roger J Daly Neil D Merrett Christopher Toon Krishna Epari Nam Q Nguyen Andrew Barbour Nikolajs Zeps Nipun Kakkar Fengmei Zhao Yuan Qing Wu Min Wang Donna M Muzny William E Fisher F Charles Brunicardi Sally E Hodges Jeffrey G Reid Jennifer Drummond Kyle Chang Yi Han Lora R Lewis Huyen Dinh Christian J Buhay Timothy Beck Lee Timms Michelle Sam Kimberly Begley Andrew Brown Deepa Pai Ami Panchal Nicholas Buchner Richard De Borja Robert E Denroche Christina K Yung Stefano Serra Nicole Onetto Debabrata Mukhopadhyay Ming-Sound Tsao Patricia A Shaw Gloria M Petersen Steven Gallinger Ralph H Hruban Anirban Maitra Christine A Iacobuzio-Donahue Richard D Schulick Christopher L Wolfgang Richard A Morgan Rita T Lawlor Paola Capelli Vincenzo Corbo Maria Scardoni Giampaolo Tortora Margaret A Tempero Karen M Mann Nancy A Jenkins Pedro A Perez-Mancera David J Adams David A Largaespada Lodewyk F A Wessels Alistair G Rust Lincoln D Stein David A Tuveson Neal G Copeland Elizabeth A Musgrove Aldo Scarpa James R Eshleman Thomas J Hudson Robert L Sutherland David A Wheeler John V Pearson John D McPherson Richard A Gibbs Sean M Grimmond

Nature 2012 Nov 24;491(7424):399-405. Epub 2012 Oct 24.

The Kinghorn Cancer Centre, 370 Victoria Street, Darlinghurst, Sydney, New South Wales 2010, Australia.

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http://dx.doi.org/10.1038/nature11547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3530898PMC
November 2012

VEGF exerts an angiogenesis-independent function in cancer cells to promote their malignant progression.

Cancer Res 2012 Aug 12;72(16):3912-8. Epub 2012 Jun 12.

Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-4058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3427728PMC
August 2012

Tumor angiogenesis 2012.

J Oncol 2012 2;2012:857383. Epub 2012 Aug 2.

Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1155/2012/857383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419421PMC
August 2012

NHERF-2 maintains endothelial homeostasis.

Blood 2012 May 17;119(20):4798-806. Epub 2012 Feb 17.

Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1182/blood-2011-11-392563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367880PMC
May 2012

Chemically modified peptides targeting the PDZ domain of GIPC as a therapeutic approach for cancer.

ACS Chem Biol 2012 Apr 15;7(4):770-9. Epub 2012 Feb 15.

Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States.

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http://dx.doi.org/10.1021/cb200536rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3331932PMC
April 2012

DNA conjugated SWCNTs enter endothelial cells via Rac1 mediated macropinocytosis.

Nano Lett 2012 Apr 6;12(4):1826-30. Epub 2012 Mar 6.

Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota 55905, USA.

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http://dx.doi.org/10.1021/nl204058uDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3324635PMC
April 2012

Cytotoxicity of naphthoquinones and their capacity to generate reactive oxygen species is quenched when conjugated with gold nanoparticles.

Int J Nanomedicine 2011 23;6:2113-22. Epub 2011 Sep 23.

Integrated Cancer Research Program, Rajiv Gandhi Centre for Biotechnology, Kerala, India.

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http://dx.doi.org/10.2147/IJN.S24074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3215152PMC
March 2012

Tissue factor pathway inhibitor blocks angiogenesis via its carboxyl terminus.

Arterioscler Thromb Vasc Biol 2012 Mar 5;32(3):704-11. Epub 2012 Jan 5.

Division of Cardiovascular Diseases, Department of Biochemistry and Molecular Biology, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1161/ATVBAHA.111.243733DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288894PMC
March 2012

Dopamine inhibits pulmonary edema through the VEGF-VEGFR2 axis in a murine model of acute lung injury.

Am J Physiol Lung Cell Mol Physiol 2012 Jan 14;302(2):L185-92. Epub 2011 Oct 14.

Dept. of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Guggenheim 1334, 200 First St. S.W., Rochester, MN 55905, USA.

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http://dx.doi.org/10.1152/ajplung.00274.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349364PMC
January 2012

Endogenous vascular endothelial growth factor-A (VEGF-A) maintains endothelial cell homeostasis by regulating VEGF receptor-2 transcription.

J Biol Chem 2012 Jan 13;287(5):3029-41. Epub 2011 Dec 13.

Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270960PMC
January 2012

Reactive oxygen species driven angiogenesis by inorganic nanorods.

Nano Lett 2011 Nov 10;11(11):4932-8. Epub 2011 Oct 10.

Department of Chemical Biology, Indian Institute of Chemical Technology, Uppal Road, Tarnaka, Hyderabad 500607, AP, India.

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http://pubs.acs.org/doi/abs/10.1021/nl2028766
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3212653PMC
November 2011

Single-molecule detection of H₂O₂ mediating angiogenic redox signaling on fluorescent single-walled carbon nanotube array.

ACS Nano 2011 Oct 21;5(10):7848-57. Epub 2011 Sep 21.

Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States.

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http://dx.doi.org/10.1021/nn201904tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850173PMC
October 2011

Tumor angiogenesis.

J Oncol 2010 19;2010. Epub 2010 Sep 19.

Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1155/2010/761671DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945670PMC
July 2011

Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function.

J Cell Sci 2011 Jul 7;124(Pt 13):2132-42. Epub 2011 Jun 7.

Department of Biochemistry and Molecular Biology, Mayo Clinic Foundation, Rochester, MN 55905, USA.

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http://dx.doi.org/10.1242/jcs.087122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3113667PMC
July 2011

Effect of hyperglycemia on human monocyte activation.

J Investig Med 2011 Apr;59(4):661-7

Division of Endocrinology and Metabolism, Mayo Clinic College of Medicine, Rochester, MN, USA.

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http://dx.doi.org/10.2310/JIM.0b013e31820ee432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143266PMC
April 2011

Structure-activity study to develop cationic lipid-conjugated haloperidol derivatives as a new class of anticancer therapeutics.

J Med Chem 2011 Apr 10;54(7):2378-90. Epub 2011 Mar 10.

Division of Lipid Science and Technology, Indian Institute of Chemical Technology, Hyderabad, Andhra Pradesh 500007, India.

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April 2011

Growth factor mediated signaling in pancreatic pathogenesis.

Cancers (Basel) 2011 Feb 24;3(1):841-71. Epub 2011 Feb 24.

Department of Biochemistry and Molecular Biology, College of Medicine, Mayo Clinic, 200 First Street SW, Guggenheim 1321C, Rochester, MN 55905, USA.

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http://dx.doi.org/10.3390/cancers3010841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756392PMC
February 2011

Pancreatic stellate cell models for transcriptional studies of desmoplasia-associated genes.

Pancreatology 2010 16;10(4):505-16. Epub 2010 Sep 16.

Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, Minn, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3214918PMC
January 2011

RGS-GAIP-interacting protein controls breast cancer progression.

Mol Cancer Res 2010 Dec 27;8(12):1591-600. Epub 2010 Oct 27.

Department of Biochemistry and Molecular Biology, Gugg 13-21C, Mayo Clinic College of Medicine, 200 First St. S.W., Rochester, MN 55905, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-10-0209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3850212PMC
December 2010

A core-shell nanomaterial with endogenous therapeutic and diagnostic functions.

Cancer Nanotechnol 2010 Dec;1(1):13-18

Department of Biochemistry and Molecular Biology, College of Medicine, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1007/s12645-010-0002-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035006PMC
December 2010

Neuropilin-1 mediates divergent R-Smad signaling and the myofibroblast phenotype.

J Biol Chem 2010 Oct 30;285(41):31840-8. Epub 2010 Jul 30.

Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951255PMC
October 2010

Both vascular endothelial growth factor and soluble Flt-1 are increased in type 2 diabetes but not in impaired fasting glucose.

J Investig Med 2010 Aug;58(6):804-6

Division of Endocrinology and Metabolism, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677544PMC
August 2010

Ephrin B2/EphB4 pathway in hepatic stellate cells stimulates Erk-dependent VEGF production and sinusoidal endothelial cell recruitment.

Am J Physiol Gastrointest Liver Physiol 2010 Jun 25;298(6):G908-15. Epub 2010 Mar 25.

Gastroenterology Research Unit, Mayo Clinic and Foundation, 200 First St. SW, Rochester, MN 55905, USA.

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June 2010

International network of cancer genome projects.

Authors:
Thomas J Hudson Warwick Anderson Axel Artez Anna D Barker Cindy Bell Rosa R Bernabé M K Bhan Fabien Calvo Iiro Eerola Daniela S Gerhard Alan Guttmacher Mark Guyer Fiona M Hemsley Jennifer L Jennings David Kerr Peter Klatt Patrik Kolar Jun Kusada David P Lane Frank Laplace Lu Youyong Gerd Nettekoven Brad Ozenberger Jane Peterson T S Rao Jacques Remacle Alan J Schafer Tatsuhiro Shibata Michael R Stratton Joseph G Vockley Koichi Watanabe Huanming Yang Matthew M F Yuen Bartha M Knoppers Martin Bobrow Anne Cambon-Thomsen Lynn G Dressler Stephanie O M Dyke Yann Joly Kazuto Kato Karen L Kennedy Pilar Nicolás Michael J Parker Emmanuelle Rial-Sebbag Carlos M Romeo-Casabona Kenna M Shaw Susan Wallace Georgia L Wiesner Nikolajs Zeps Peter Lichter Andrew V Biankin Christian Chabannon Lynda Chin Bruno Clément Enrique de Alava Françoise Degos Martin L Ferguson Peter Geary D Neil Hayes Thomas J Hudson Amber L Johns Arek Kasprzyk Hidewaki Nakagawa Robert Penny Miguel A Piris Rajiv Sarin Aldo Scarpa Tatsuhiro Shibata Marc van de Vijver P Andrew Futreal Hiroyuki Aburatani Mónica Bayés David D L Botwell Peter J Campbell Xavier Estivill Daniela S Gerhard Sean M Grimmond Ivo Gut Martin Hirst Carlos López-Otín Partha Majumder Marco Marra John D McPherson Hidewaki Nakagawa Zemin Ning Xose S Puente Yijun Ruan Tatsuhiro Shibata Michael R Stratton Hendrik G Stunnenberg Harold Swerdlow Victor E Velculescu Richard K Wilson Hong H Xue Liu Yang Paul T Spellman Gary D Bader Paul C Boutros Peter J Campbell Paul Flicek Gad Getz Roderic Guigó Guangwu Guo David Haussler Simon Heath Tim J Hubbard Tao Jiang Steven M Jones Qibin Li Nuria López-Bigas Ruibang Luo Lakshmi Muthuswamy B F Francis Ouellette John V Pearson Xose S Puente Victor Quesada Benjamin J Raphael Chris Sander Tatsuhiro Shibata Terence P Speed Lincoln D Stein Joshua M Stuart Jon W Teague Yasushi Totoki Tatsuhiko Tsunoda Alfonso Valencia David A Wheeler Honglong Wu Shancen Zhao Guangyu Zhou Lincoln D Stein Roderic Guigó Tim J Hubbard Yann Joly Steven M Jones Arek Kasprzyk Mark Lathrop Nuria López-Bigas B F Francis Ouellette Paul T Spellman Jon W Teague Gilles Thomas Alfonso Valencia Teruhiko Yoshida Karen L Kennedy Myles Axton Stephanie O M Dyke P Andrew Futreal Daniela S Gerhard Chris Gunter Mark Guyer Thomas J Hudson John D McPherson Linda J Miller Brad Ozenberger Kenna M Shaw Arek Kasprzyk Lincoln D Stein Junjun Zhang Syed A Haider Jianxin Wang Christina K Yung Anthony Cros Anthony Cross Yong Liang Saravanamuttu Gnaneshan Jonathan Guberman Jack Hsu Martin Bobrow Don R C Chalmers Karl W Hasel Yann Joly Terry S H Kaan Karen L Kennedy Bartha M Knoppers William W Lowrance Tohru Masui Pilar Nicolás Emmanuelle Rial-Sebbag Laura Lyman Rodriguez Catherine Vergely Teruhiko Yoshida Sean M Grimmond Andrew V Biankin David D L Bowtell Nicole Cloonan Anna deFazio James R Eshleman Dariush Etemadmoghadam Brooke B Gardiner Brooke A Gardiner James G Kench Aldo Scarpa Robert L Sutherland Margaret A Tempero Nicola J Waddell Peter J 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Masson-Jacquemier Mark Lathrop Iris Pauporté Xavier Pivot Anne Vincent-Salomon Eric Tabone Charles Theillet Gilles Thomas Jörg Tost Isabelle Treilleux Fabien Calvo Paulette Bioulac-Sage Bruno Clément Thomas Decaens Françoise Degos Dominique Franco Ivo Gut Marta Gut Simon Heath Mark Lathrop Didier Samuel Gilles Thomas Jessica Zucman-Rossi Peter Lichter Roland Eils Benedikt Brors Jan O Korbel Andrey Korshunov Pablo Landgraf Hans Lehrach Stefan Pfister Bernhard Radlwimmer Guido Reifenberger Michael D Taylor Christof von Kalle Partha P Majumder Rajiv Sarin T S Rao M K Bhan Aldo Scarpa Paolo Pederzoli Rita A Lawlor Massimo Delledonne Alberto Bardelli Andrew V Biankin Sean M Grimmond Thomas Gress David Klimstra Giuseppe Zamboni Tatsuhiro Shibata Yusuke Nakamura Hidewaki Nakagawa Jun Kusada Tatsuhiko Tsunoda Satoru Miyano Hiroyuki Aburatani Kazuto Kato Akihiro Fujimoto Teruhiko Yoshida Elias Campo Carlos López-Otín Xavier Estivill Roderic Guigó Silvia de Sanjosé Miguel A Piris Emili Montserrat Marcos González-Díaz Xose S Puente Pedro Jares Alfonso Valencia Heinz Himmelbauer Heinz Himmelbaue Victor Quesada Silvia Bea Michael R Stratton P Andrew Futreal Peter J Campbell Anne Vincent-Salomon Andrea L Richardson Jorge S Reis-Filho Marc van de Vijver Gilles Thomas Jocelyne D Masson-Jacquemier Samuel Aparicio Ake Borg Anne-Lise Børresen-Dale Carlos Caldas John A Foekens Hendrik G Stunnenberg Laura van't Veer Douglas F Easton Paul T Spellman Sancha Martin Anna D Barker Lynda Chin Francis S Collins Carolyn C Compton Martin L Ferguson Daniela S Gerhard Gad Getz Chris Gunter Alan Guttmacher Mark Guyer D Neil Hayes Eric S Lander Brad Ozenberger Robert Penny Jane Peterson Chris Sander Kenna M Shaw Terence P Speed Paul T Spellman Joseph G Vockley David A Wheeler Richard K Wilson Thomas J Hudson Lynda Chin Bartha M Knoppers Eric S Lander Peter Lichter Lincoln D Stein Michael R Stratton Warwick Anderson Anna D Barker Cindy Bell Martin Bobrow Wylie Burke Francis S Collins Carolyn C Compton Ronald A DePinho Douglas F Easton P Andrew Futreal Daniela S Gerhard Anthony R Green Mark Guyer Stanley R Hamilton Tim J Hubbard Olli P Kallioniemi Karen L Kennedy Timothy J Ley Edison T Liu Youyong Lu Partha Majumder Marco Marra Brad Ozenberger Jane Peterson Alan J Schafer Paul T Spellman Hendrik G Stunnenberg Brandon J Wainwright Richard K Wilson Huanming Yang

Nature 2010 Apr;464(7291):993-8

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April 2010