Deanna L Kroetz

Deanna L Kroetz

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Deanna L Kroetz

Publications by authors named "Deanna L Kroetz"

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Apical Shear Stress Enhanced Organic Cation Transport in Human OCT2/MATE1-Transfected Madin-Darby Canine Kidney Cells Involves Ciliary Sensing.

J Pharmacol Exp Ther 2019 Jun 25;369(3):523-530. Epub 2019 Mar 25.

Departments of Bioengineering and Therapeutic Sciences (A.J., P.S., D.L.K., S.R.) and Pediatrics (P.R.B.), University of California San Francisco (UCSF), San Francisco, California; and Department of Medicine, Division of Nephrology, Vanderbilt University Medical Center, Nashville, Tennessee (N.F., W.F.).

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http://dx.doi.org/10.1124/jpet.118.255026DOI Listing
June 2019

Efficient estimation of grouped survival models.

BMC Bioinformatics 2019 May 28;20(1):269. Epub 2019 May 28.

Department of Biostatistics and Bioinformatics, Duke University, Durham, USA.

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http://dx.doi.org/10.1186/s12859-019-2899-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6540566PMC
May 2019

Rare Variants in the Promoter Modulate In Vivo Activity.

Drug Metab Dispos 2018 05 21;46(5):636-642. Epub 2018 Feb 21.

Department of Bioengineering and Therapeutic Sciences (R.J.E., M.J.K., R.S., N.A., D.L.K.) and Institute for Human Genetics (N.A., M.J.K., R.S., D.L.K.), University of California San Francisco, San Francisco, California

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http://dmd.aspetjournals.org/lookup/doi/10.1124/dmd.117.0795
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http://dx.doi.org/10.1124/dmd.117.079541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5896364PMC
May 2018

Dicloxacillin induces CYP2C19, CYP2C9 and CYP3A4 in vivo and in vitro.

Br J Clin Pharmacol 2018 03 10;84(3):510-519. Epub 2018 Jan 10.

Department of Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark.

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http://doi.wiley.com/10.1111/bcp.13467
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http://dx.doi.org/10.1111/bcp.13467DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5809358PMC
March 2018

Bevacizumab-induced hypertension: Clinical presentation and molecular understanding.

Pharmacol Ther 2018 02 4;182:152-160. Epub 2017 Sep 4.

Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01637258173022
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http://dx.doi.org/10.1016/j.pharmthera.2017.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785435PMC
February 2018

Clinical Pharmacokinetics of Paclitaxel Monotherapy: An Updated Literature Review.

Clin Pharmacokinet 2018 01;57(1):7-19

Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/s40262-017-0563-zDOI Listing
January 2018

ABCG2 regulatory single-nucleotide polymorphisms alter in vivo enhancer activity and expression.

Pharmacogenet Genomics 2017 Dec;27(12):454-463

aDepartment of Bioengineering and Therapeutic Sciences bInstitute for Human Genetics, University of California San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5678922PMC
December 2017

In Vivo Hepatic Enhancer Elements in the Human ABCG2 Locus.

Drug Metab Dispos 2017 02 17;45(2):208-215. Epub 2016 Nov 17.

Department of Bioengineering and Therapeutic Sciences (R.J.E., M.J.K., R.P.S., X.L., N.A., D.L.K.); and Institute for Human Genetics (M.J.K., R.P.S., N.A., D.L.K.), University of California, San Francisco, San Francisco, California

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http://dx.doi.org/10.1124/dmd.116.072033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267518PMC
February 2017

Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans.

AIDS 2016 07;30(11):1807-15

aDepartment of Medicine bDepartment of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California cDepartment of Medicine, Vanderbilt University School of Medicine dDepartment of Medicine, Meharry Medical College, Nashville, Tennessee, USA eDepartment of Life Sciences, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland fRIKEN Center for Genomic Medicine, Kanagawa, Japan gDepartment of Medicine, Mbarara University of Science and Technology, Mbarara, Uganda.

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http://pdfs.journals.lww.com/aidsonline/2016/07170/Host_gene
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http://dx.doi.org/10.1097/QAD.0000000000001124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4925250PMC
July 2016

Multidrug resistance-associated protein 4 is a determinant of arsenite resistance.

Oncol Rep 2016 Jan 22;35(1):147-54. Epub 2015 Oct 22.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.3892/or.2015.4343DOI Listing
January 2016

Pharmacoethnicity in Paclitaxel-Induced Sensory Peripheral Neuropathy.

Clin Cancer Res 2015 Oct 26;21(19):4337-46. Epub 2015 May 26.

Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-0133DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4592389PMC
October 2015

PharmGKB summary: very important pharmacogene information for human leukocyte antigen B.

Pharmacogenet Genomics 2015 Apr;25(4):205-21

Departments of aGenetics bBioengineering, Stanford University, Stanford cDepartment of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4356642PMC
April 2015

Genomic architecture of pharmacological efficacy and adverse events.

Pharmacogenomics 2014 Dec;15(16):2025-48

Department of Bioengineering & Therapeutic Sciences, Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.2217/pgs.14.144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308414PMC
December 2014

PharmGKB summary: abacavir pathway.

Pharmacogenet Genomics 2014 May;24(5):276-82

Departments of aGenetics bBioengineering, Stanford University, Stanford cDepartment of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California, USA.

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http://dx.doi.org/10.1097/FPC.0000000000000040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074515PMC
May 2014

ABCC4 is regulated by microRNA-124a and microRNA-506.

Biochem Pharmacol 2014 Feb 30;87(3):515-22. Epub 2013 Oct 30.

Department of Bioengineering and Therapeutic Sciences (SMM, DLK) and Institute for Human Genetics (DLK) , 1550 4th Street RH584E, San Francisco, CA 94158-2911, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcp.2013.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3927324PMC
February 2014

Epoxyeicosatrienoic acids prevent cisplatin-induced renal apoptosis through a p38 mitogen-activated protein kinase-regulated mitochondrial pathway.

Mol Pharmacol 2013 Dec 3;84(6):925-34. Epub 2013 Oct 3.

Departments of Bioengineering and Therapeutic Sciences (Y.L., X.L., S.N., D.L.K.) and Anatomic Pathology (J.L.O.), University of California San Francisco, San Francisco, California; and Arête Therapeutics, Hayward, California (H.K.W.).

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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.113.08
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http://dx.doi.org/10.1124/mol.113.088302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3834146PMC
December 2013

Measuring the overall genetic component of nevirapine pharmacokinetics and the role of selected polymorphisms: towards addressing the missing heritability in pharmacogenetic phenotypes?

Pharmacogenet Genomics 2013 Nov;23(11):591-6

Departments of aBioengineering and Therapeutic Sciences bEpidemiology cMedicine dThe Institute for Human Genetics, University of California, San Francisco, California eRagon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Massachusetts General Hospital Center for Global Health, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32836533a5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4048019PMC
November 2013

Genome-wide association studies in pharmacogenomics: successes and lessons.

Pharmacogenet Genomics 2013 Aug;23(8):383-94

Department of Statistics, Bioinformatics Research Center, North Carolina State University, Raleigh, North Carolina 27695-7566, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32833d7b45DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003940PMC
August 2013

Abacavir pharmacogenetics--from initial reports to standard of care.

Pharmacotherapy 2013 Jul 3;33(7):765-75. Epub 2013 May 3.

Department of Bioengineering and Therapeutic Sciences, University of California, San Francisco, California, USA.

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http://doi.wiley.com/10.1002/phar.1278
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http://dx.doi.org/10.1002/phar.1278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700656PMC
July 2013

The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance).

Pharmacogenet Genomics 2013 Jan;23(1):29-33

Sections of Clinical Pharmacology and Hematology/Oncology, Department of Medicine, The Geisel School of Medicine at Dartmouth, The Norris Cotton Cancer Center, Lebanon, NH 03756, USA.

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http://dx.doi.org/10.1097/FPC.0b013e32835b16d8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647228PMC
January 2013

Exploiting the complexity of the genome and transcriptome using pharmacogenomics towards personalized medicine.

Genome Biol 2011 17;12(1):301. Epub 2011 Jan 17.

Dr Margarete Fischer-Bosch-Institute of Clinical Pharmacology, Auerbachstrasse 112, 70376 Stuttgart, Germany.

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http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
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http://dx.doi.org/10.1186/gb-2011-12-1-301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3091296PMC
February 2012

Contribution of aquaporin 9 and multidrug resistance-associated protein 2 to differential sensitivity to arsenite between primary cultured chorion and amnion cells prepared from human fetal membranes.

Toxicol Appl Pharmacol 2011 Dec 16;257(2):198-208. Epub 2011 Sep 16.

Department of Clinical Molecular Genetics, School of Pharmacy, Tokyo University of Pharmacy & Life Sciences, Horinouchi, Hachioji, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.taap.2011.09.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470788PMC
December 2011

Very important pharmacogene summary: ABCB1 (MDR1, P-glycoprotein).

Pharmacogenet Genomics 2011 Mar;21(3):152-61

Department of Genetics, Stanford University Medical Center, Stanford, California 94305-5120, USA.

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http://dx.doi.org/10.1097/FPC.0b013e3283385a1cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098758PMC
March 2011

Functional hot spots in human ATP-binding cassette transporter nucleotide binding domains.

Protein Sci 2010 Nov;19(11):2110-21

Graduate Group in Bioinformatics, University of California at San Francisco, San Francisco, California, USA.

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http://doi.wiley.com/10.1002/pro.491
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http://dx.doi.org/10.1002/pro.491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005782PMC
November 2010

A survey of integral alpha-helical membrane proteins.

J Struct Funct Genomics 2009 Dec 17;10(4):269-80. Epub 2009 Sep 17.

Graduate Group in Bioinformatics, University of California at San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/s10969-009-9069-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780624PMC
December 2009

Institutional Profile: The University of California Pharmacogenomics Center: at the interface of genomics, biological mechanisms and drug therapy.

Pharmacogenomics 2009 Oct;10(10):1569-76

Department of Bioengineering and Therapeutic Sciences, Schools of Pharmacy and Medicine, University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.2217/pgs.09.119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923222PMC
October 2009

Steady state bioequivalence of generic and innovator formulations of stavudine, lamivudine, and nevirapine in HIV-infected Ugandan adults.

PLoS One 2008 19;3(12):e3981. Epub 2008 Dec 19.

Division of Epidemiology, School of Public Health, University of California Berkeley, Berkeley, California, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0003981PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2602850PMC
February 2009

Inhibition of soluble epoxide hydrolase does not protect against endotoxin-mediated hepatic inflammation.

J Pharmacol Exp Ther 2008 Dec 24;327(3):707-15. Epub 2008 Sep 24.

Department of Biopharmaceutical Sciences, University of California, San Francisco, California, USA.

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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.108.14239
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http://dx.doi.org/10.1124/jpet.108.142398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761654PMC
December 2008

Nicotine metabolism in pregnant and nonpregnant rabbits.

Nicotine Tob Res 2008 Aug;10(8):1385-90

Division of Clinical Pharmacology and Experimental Therapeutics, Medical Service, San Francisco General Hospital Medical Center, 1550 4th Street, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1080/14622200802238878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923225PMC
August 2008

Substrate-dependent effects of human ABCB1 coding polymorphisms.

J Pharmacol Exp Ther 2008 May 20;325(2):435-42. Epub 2008 Feb 20.

UCSF Box 2911, 1550 4th St., Rm. RH584E, San Francisco, CA 94158-2911, USA.

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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.107.13519
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http://dx.doi.org/10.1124/jpet.107.135194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612726PMC
May 2008

The effects of ABCB1 3'-untranslated region variants on mRNA stability.

Drug Metab Dispos 2008 Jan 16;36(1):10-5. Epub 2007 Oct 16.

The Department of Biopharmaceutical Sciences, University of California, San Francisco, California 94158-2911, USA.

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http://dx.doi.org/10.1124/dmd.107.017087DOI Listing
January 2008

Cytochrome P450 eicosanoids are activators of peroxisome proliferator-activated receptor alpha.

Drug Metab Dispos 2007 Jul 12;35(7):1126-34. Epub 2007 Apr 12.

Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, CA 94143-2911, USA.

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http://dx.doi.org/10.1124/dmd.106.013839DOI Listing
July 2007

Interindividual variability in the effect of atazanavir and saquinavir on the expression of lymphocyte P-glycoprotein.

J Antimicrob Chemother 2007 Jul 17;60(1):61-7. Epub 2007 May 17.

Department of Biopharmaceutical Sciences, University of California San Francisco, 1550 4th Street, San Francisco, CA 94158, USA.

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http://dx.doi.org/10.1093/jac/dkm135DOI Listing
July 2007

Adherence-resistance relationships to combination HIV antiretroviral therapy.

Curr HIV/AIDS Rep 2007 May;4(2):65-72

San Francisco General Hospital, UCSF, 1001 Potrero Avenue, Building 100, Room 301, San Francisco, CA 94110, USA.

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May 2007

Function-altering SNPs in the human multidrug transporter gene ABCB1 identified using a Saccharomyces-based assay.

PLoS Genet 2007 Mar;3(3):e39

Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America.

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http://dx.plos.org/10.1371/journal.pgen.0030039
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http://dx.doi.org/10.1371/journal.pgen.0030039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1817653PMC
March 2007

Inhibition of smooth muscle proliferation by urea-based alkanoic acids via peroxisome proliferator-activated receptor alpha-dependent repression of cyclin D1.

Arterioscler Thromb Vasc Biol 2006 Nov 17;26(11):2462-8. Epub 2006 Aug 17.

Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, CA 94143-2911, USA.

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https://www.ahajournals.org/doi/10.1161/01.ATV.0000242013.29
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http://dx.doi.org/10.1161/01.ATV.0000242013.29441.81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1904341PMC
November 2006

CYP4 isoform specificity in the omega-hydroxylation of phytanic acid, a potential route to elimination of the causative agent of Refsum's disease.

J Pharmacol Exp Ther 2006 Aug 17;318(2):835-9. Epub 2006 May 17.

Department of Pharmaceutical Chemistry, University of California, San Francisco, CA 94143-2280, USA.

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http://dx.doi.org/10.1124/jpet.106.104976DOI Listing
August 2006

Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary gamma-linolenic acid.

J Pharmacol Exp Ther 2006 May 18;317(2):732-8. Epub 2006 Jan 18.

Department of Biopharmaceutical Sciences, University of California San Francisco, San Francisco, CA 94143, USA.

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http://dx.doi.org/10.1124/jpet.105.098558DOI Listing
May 2006

Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability.

Pharmacogenet Genomics 2005 Oct;15(10):693-704

Department of Pharmacology, Program in Pharmacogenomics, College of Medicine and Public Health, The Ohio State University, Columbus, Ohio 43210, USA.

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October 2005

Regulation and inhibition of arachidonic acid omega-hydroxylases and 20-HETE formation.

Annu Rev Pharmacol Toxicol 2005 ;45:413-38

Department of Biopharmaceutical Sciences, University of California, San Francisco, California 94143-2911, USA.

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http://www.annualreviews.org/doi/10.1146/annurev.pharmtox.45
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http://dx.doi.org/10.1146/annurev.pharmtox.45.120403.100045DOI Listing
May 2005

Functional implications of genetic polymorphisms in the multidrug resistance gene MDR1 (ABCB1).

Pharm Res 2004 Jun;21(6):904-13

Division of Clinical Pharmacology, Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1023/b:pham.0000029276.21063.0bDOI Listing
June 2004

Vascular localization of soluble epoxide hydrolase in the human kidney.

Am J Physiol Renal Physiol 2004 Apr 9;286(4):F720-6. Epub 2003 Dec 9.

Dept. of Biopharmaceutical Sciences, Univ. of California San Francisco, 513 Parnassus, Box 0446, San Francisco, CA 94143-0446, USA.

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http://dx.doi.org/10.1152/ajprenal.00165.2003DOI Listing
April 2004

Catalytic activity and isoform-specific inhibition of rat cytochrome p450 4F enzymes.

J Pharmacol Exp Ther 2004 Mar 21;308(3):887-95. Epub 2003 Nov 21.

Department of Biopharmaceutical Sciences, University of California, San Francisco, CA 94143-0446, USA.

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http://jpet.aspetjournals.org/cgi/doi/10.1124/jpet.103.05962
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http://dx.doi.org/10.1124/jpet.103.059626DOI Listing
March 2004

No effect of MDR1 C3435T variant on loperamide disposition and central nervous system effects.

Clin Pharmacol Ther 2003 Nov;74(5):487-98

Department of Biopharmaceutical Sciences, University of California, San Francisco, CA 94143-0446, USA.

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http://doi.wiley.com/10.1016/S0009-9236(03)00234-0
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http://dx.doi.org/10.1016/S0009-9236(03)00234-0DOI Listing
November 2003

Antihypertensive effect of mechanism-based inhibition of renal arachidonic acid omega-hydroxylase activity.

Am J Physiol Regul Integr Comp Physiol 2002 Sep;283(3):R710-20

Department of Biopharmaceutical Sciences, School of Pharmacy, University of California, San Francisco, California 94143, USA.

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http://www.physiology.org/doi/10.1152/ajpregu.00522.2001
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http://dx.doi.org/10.1152/ajpregu.00522.2001DOI Listing
September 2002

MDR1 reference sequence and reference function.

Clin Pharmacol Ther 2002 Jul;72(1):100-1

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http://dx.doi.org/10.1067/mcp.2002.125561DOI Listing
July 2002

Cytochrome P450 pathways of arachidonic acid metabolism.

Curr Opin Lipidol 2002 Jun;13(3):273-83

Department of Biopharmaceutical Sciences, School of Pharmacy, University of California, San Francisco, USA.

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June 2002

Covalent attachment of the heme prosthetic group in the CYP4F cytochrome P450 family.

Biochemistry 2002 May;41(18):5931-7

Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143-0446, USA.

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http://dx.doi.org/10.1021/bi025527yDOI Listing
May 2002

Candidate gene approach for pharmacogenetic studies.

Pharmacogenomics 2002 Jan;3(1):47-56

Incyte Genomics, Inc., 3174 Porter Drive, Palo Alto, California 94304, USA.

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http://dx.doi.org/10.1517/14622416.3.1.47DOI Listing
January 2002