Dean Jones

Dean Jones

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Maternal serum metabolome and traffic-related air pollution exposure in pregnancy.

Environ Int 2019 Sep 20;130:104872. Epub 2019 Jun 20.

Department of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, CA, USA; Department of Neurology, UCLA School of Medicine, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2019.05.066DOI Listing
September 2019

A precision medicine approach to defining the impact of doxorubicin on the bioenergetic-metabolite interactome in human platelets.

Redox Biol 2019 Sep 7;28:101311. Epub 2019 Sep 7.

Mitochondrial Medicine Laboratory, Center for Free Radical Biology, Department of Pathology, University of Alabama at Birmingham, USA. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101311DOI Listing
September 2019

Environmental Cadmium Enhances Lung Injury by Respiratory Syncytial Virus Infection.

Am J Pathol 2019 Aug 18;189(8):1513-1525. Epub 2019 May 18.

Division of Pulmonary Medicine, Department of Medicine, Emory University, Atlanta, Georgia. Electronic address:

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http://dx.doi.org/10.1016/j.ajpath.2019.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717913PMC
August 2019

Metabolome Wide Association Study of Serum Poly and Perfluoroalkyl Substances (PFASs) in Pregnancy and Early Postpartum.

Reprod Toxicol 2019 Aug 20;87:70-78. Epub 2019 May 20.

The Center for Research on Women and Children's Health, Child Health and Development Studies, Public Health Institute, 1683 Shattuck Avenue, Suite B, Berkeley, CA 94709, USA. Electronic address:

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http://dx.doi.org/10.1016/j.reprotox.2019.05.058DOI Listing
August 2019

Response of Beef Cattle Fecal Microbiota to Grazing on Toxic Tall Fescue.

Appl Environ Microbiol 2019 Aug 18;85(15). Epub 2019 Jul 18.

Interdisciplinary Toxicology Program, University of Georgia, Athens, Georgia, USA

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http://dx.doi.org/10.1128/AEM.00032-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6643230PMC
August 2019

Understanding mixed environmental exposures using metabolomics via a hierarchical community network model in a cohort of California women in 1960's.

Reprod Toxicol 2019 Jul 9. Epub 2019 Jul 9.

The Center for Research on Women and Children's Health, Child Health and Development Studies, Public Health Institute, 1683 Shattuck Avenue, Suite B, Berkeley, CA, 94709, USA. Electronic address:

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http://dx.doi.org/10.1016/j.reprotox.2019.06.013DOI Listing
July 2019

Transcriptome Analysis Reveals Distinct Responses to Physiologic Toxic Manganese Exposure in Human Neuroblastoma Cells.

Front Genet 2019 24;10:676. Epub 2019 Jul 24.

Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University, Atlanta, GA, United States.

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http://dx.doi.org/10.3389/fgene.2019.00676DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668488PMC
July 2019

Metabolomic assessment of exposure to near-highway ultrafine particles.

J Expo Sci Environ Epidemiol 2019 Jun 5;29(4):469-483. Epub 2018 Dec 5.

Department of Civil and Environmental Engineering, Tufts University, Medford, MA, USA.

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http://dx.doi.org/10.1038/s41370-018-0102-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6551325PMC
June 2019

Low-dose cadmium potentiates lung inflammatory response to 2009 pandemic H1N1 influenza virus in mice.

Environ Int 2019 06 15;127:720-729. Epub 2019 Apr 15.

Division of Pulmonary, Allergy and Critical Care Medicine, Emory University School of Medicine, Atlanta, GA 30322, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2019.03.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6536378PMC
June 2019

Metabolomics of childhood exposure to perfluoroalkyl substances: a cross-sectional study.

Metabolomics 2019 Jun 21;15(7):95. Epub 2019 Jun 21.

Department of Epidemiology, School of Public Health, Brown University, Box G-S121-2, Providence, RI, 02912, USA.

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http://dx.doi.org/10.1007/s11306-019-1560-zDOI Listing
June 2019

Metabolomic Responses to Manganese Dose in SH-SY5Y Human Neuroblastoma Cells.

Toxicol Sci 2019 May;169(1):84-94

Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University, Atlanta, Georgia.

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https://academic.oup.com/toxsci/advance-article/doi/10.1093/
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http://dx.doi.org/10.1093/toxsci/kfz028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6484887PMC
May 2019

Multigenerational metabolic profiling in the Michigan PBB registry.

Environ Res 2019 May 13;172:182-193. Epub 2019 Feb 13.

Department of Civil and Environmental Engineering, Tufts University, 200 College Ave, Medford MA 02155, United States. Electronic address:

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http://dx.doi.org/10.1016/j.envres.2019.02.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534816PMC
May 2019

Metabolome Wide Association Study of serum DDT and DDE in Pregnancy and Early Postpartum.

Reprod Toxicol 2019 May 15. Epub 2019 May 15.

The Center for Research on Women and Children's Health, Child Health and Development Studies, Public Health Institute, 1683 Shattuck Avenue, Suite B, Berkeley, CA 94709, USA. Electronic address:

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http://dx.doi.org/10.1016/j.reprotox.2019.05.059DOI Listing
May 2019

Enhanced Keap1-Nrf2 signaling protects the myocardium from isoproterenol-induced pathological remodeling in mice.

Redox Biol 2019 May 4:101212. Epub 2019 May 4.

Cardiac Aging & Redox Signaling Laboratory, Division of Molecular & Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA; Center for Free Radical Biology, University of Alabama at Birmingham, Birmingham, AL, USA; Division of Cardiovascular Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101212DOI Listing
May 2019

Mitochondria in precision medicine; linking bioenergetics and metabolomics in platelets.

Redox Biol 2019 04 10;22:101165. Epub 2019 Mar 10.

Mitochondrial Medicine Laboratory, Department of Pathology, University of Alabama at Birmingham, UK. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2019.101165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6436140PMC
April 2019

Redox Systems Biology of Nutrition and Oxidative Stress.

J Nutr 2019 Apr;149(4):553-565

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, GA.

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https://academic.oup.com/jn/advance-article/doi/10.1093/jn/n
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http://dx.doi.org/10.1093/jn/nxy306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461723PMC
April 2019

Neonatal intestinal immune regulation by the commensal bacterium, P. UF1.

Mucosal Immunol 2019 03 15;12(2):434-444. Epub 2019 Jan 15.

Department of Infectious Diseases & Immunology, University of Florida, Gainesville, FL, USA.

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http://www.nature.com/articles/s41385-018-0125-1
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http://dx.doi.org/10.1038/s41385-018-0125-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375783PMC
March 2019

Metabolic perturbations in classic galactosemia beyond the Leloir pathway: Insights from an untargeted metabolomic study.

J Inherit Metab Dis 2019 Mar 22;42(2):254-263. Epub 2019 Jan 22.

Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia.

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http://dx.doi.org/10.1002/jimd.12007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6414239PMC
March 2019

Role of heat shock protein and cytokine expression as markers of clinical outcomes with glutamine-supplemented parenteral nutrition in surgical ICU patients.

Clin Nutr 2019 Mar 13. Epub 2019 Mar 13.

Division of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA; Center for Clinical and Molecular Nutrition, Emory University School of Medicine, Atlanta, GA 30322, USA; Atlanta Veterans Affairs Medical Center, Decatur, GA 30033, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clnu.2019.02.045DOI Listing
March 2019

Redox Equivalents and Mitochondrial Bioenergetics.

Methods Mol Biol 2018 ;1782:197-227

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.1007/978-1-4939-7831-1_12DOI Listing
February 2019

The metabolome as a biomarker of mortality risk in the common marmoset.

Am J Primatol 2019 Feb 26;81(2):e22944. Epub 2018 Dec 26.

Division of Pulmonary Allergy and Critical Care, Department of Medicine, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1002/ajp.22944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599709PMC
February 2019

A biplot correlation range for group-wise metabolite selection in mass spectrometry.

BioData Min 2019 4;12. Epub 2019 Feb 4.

6Department of Industrial Engineering, Hanyang University, Seoul, 04763 South Korea.

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https://biodatamining.biomedcentral.com/articles/10.1186/s13
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http://dx.doi.org/10.1186/s13040-019-0191-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360680PMC
February 2019

The Exposome: Molecules to Populations.

Annu Rev Pharmacol Toxicol 2019 Jan 10;59:107-127. Epub 2018 Aug 10.

Department of Environmental Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA.

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https://www.annualreviews.org/doi/10.1146/annurev-pharmtox-0
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http://dx.doi.org/10.1146/annurev-pharmtox-010818-021315DOI Listing
January 2019

Symptom Science Research in the Era of Big Data: Leveraging Interdisciplinary Resources and Partners to Make It Happen.

J Nurs Scholarsh 2019 Jan 19;51(1):4-8. Epub 2018 Nov 19.

Associate Professor, Emory University Nell Hodgson Woodruff School of Nursing, Atlanta, GA, USA.

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http://doi.wiley.com/10.1111/jnu.12446
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http://dx.doi.org/10.1111/jnu.12446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329647PMC
January 2019

Metabolome-wide association study of anti-epileptic drug treatment during pregnancy.

Toxicol Appl Pharmacol 2019 01 4;363:122-130. Epub 2018 Dec 4.

Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, Emory University School of Medicine, Atlanta, GA, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0041008X183053
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http://dx.doi.org/10.1016/j.taap.2018.12.001DOI Listing
January 2019

Phytochelatin database: a resource for phytochelatin complexes of nutritional and environmental metals.

Database (Oxford) 2019 01;2019

Nutrition and Health Sciences, Laney Graduate School, Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.1093/database/baz083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606759PMC
January 2019

Selenium at the redox interface of the genome, metabolome and exposome.

Free Radic Biol Med 2018 11 5;127:215-227. Epub 2018 Jun 5.

Department of Medicine, Emory University, Atlanta, GA 30322, United States. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2018.06.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168380PMC
November 2018

Determination of thiocyanate in exhaled breath condensate.

Free Radic Biol Med 2018 10 22;126:334-340. Epub 2018 Aug 22.

Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2018.08.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166650PMC
October 2018

Myeloperoxidase oxidation of methionine associates with early cystic fibrosis lung disease.

Eur Respir J 2018 10 10;52(4). Epub 2018 Oct 10.

Division of Respiratory Medicine and Allergology, Dept of Pediatrics, University Medical Center Rotterdam, Erasmus MC-Sophia, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1183/13993003.01118-2018DOI Listing
October 2018

Putrescine as indicator of manganese neurotoxicity: Dose-response study in human SH-SY5Y cells.

Food Chem Toxicol 2018 Jun 21;116(Pt B):272-280. Epub 2018 Apr 21.

Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, Emory University, Atlanta, GA, 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2018.04.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6008158PMC
June 2018

Selenium Supplementation Alters Hepatic Energy and Fatty Acid Metabolism in Mice.

J Nutr 2018 05;148(5):675-684

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, GA.

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http://dx.doi.org/10.1093/jn/nxy036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454983PMC
May 2018

Untargeted metabolomics reveals multiple metabolites influencing smoking-related DNA methylation.

Epigenomics 2018 04 12;10(4):379-393. Epub 2018 Mar 12.

Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.2217/epi-2017-0101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5925442PMC
April 2018

Selenium supplementation prevents metabolic and transcriptomic responses to cadmium in mouse lung.

Biochim Biophys Acta Gen Subj 2018 Apr 12. Epub 2018 Apr 12.

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbagen.2018.04.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6188826PMC
April 2018

Human Suction Blister Fluid Composition Determined Using High-Resolution Metabolomics.

Anal Chem 2018 03 27;90(6):3786-3792. Epub 2018 Feb 27.

Department of Environmental Health, Rollins School of Public Health , Emory University , Atlanta , Georgia 30322 , United States.

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http://dx.doi.org/10.1021/acs.analchem.7b04073DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5863097PMC
March 2018

xMWAS: a data-driven integration and differential network analysis tool.

Bioinformatics 2018 02;34(4):701-702

Clinical Biomarkers Laboratory, Department of Medicine, Emory University, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1093/bioinformatics/btx656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860615PMC
February 2018

Mitochondrial network responses in oxidative physiology and disease.

Free Radic Biol Med 2018 02 6;116:31-40. Epub 2018 Jan 6.

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2018.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5833979PMC
February 2018

Higher Mediterranean Diet Quality Scores and Lower Body Mass Index Are Associated with a Less-Oxidized Plasma Glutathione and Cysteine Redox Status in Adults.

J Nutr 2018 02;148(2):245-253

Center for Clinical and Molecular Nutrition and Divisions of Cardiology and Endocrinology, Metabolism & Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA.

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http://dx.doi.org/10.1093/jn/nxx045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251672PMC
February 2018

ADAP-GC 3.2: Graphical Software Tool for Efficient Spectral Deconvolution of Gas Chromatography-High-Resolution Mass Spectrometry Metabolomics Data.

J Proteome Res 2018 01 7;17(1):470-478. Epub 2017 Nov 7.

University of North Carolina at Charlotte , Charlotte, North Carolina 28223, United States.

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http://dx.doi.org/10.1021/acs.jproteome.7b00633DOI Listing
January 2018

Oxidative stress predicts cognitive decline with aging in healthy adults: an observational study.

J Neuroinflammation 2018 Jan 16;15(1):17. Epub 2018 Jan 16.

Emory Univeristy, 1841 Clifton Road NE, Atlanta, GA, 30329, United States.

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http://dx.doi.org/10.1186/s12974-017-1026-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5771063PMC
January 2018

Association between oxidative stress and atrial fibrillation.

Heart Rhythm 2017 12 27;14(12):1849-1855. Epub 2017 Jul 27.

Division of Cardiology, Emory University School of Medicine, Emory Clinical Cardiovascular Research Institute, Atlanta, Georgia. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2017.07.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817893PMC
December 2017

Metabolomic profiles of plasma, exhaled breath condensate, and saliva are correlated with potential for air toxics detection.

J Breath Res 2017 12 6;12(1):016008. Epub 2017 Dec 6.

Department of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, United States of America.

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http://dx.doi.org/10.1088/1752-7163/aa863cDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5803078PMC
December 2017

Metabolome-wide association study of peripheral parasitemia in Plasmodium vivax malaria.

Int J Med Microbiol 2017 Dec 6;307(8):533-541. Epub 2017 Sep 6.

Division of Pulmonary, Allergy and Critical Care Medicine, School of Medicine, Emory University, Atlanta, GA, USA; Malaria Host-Pathogen Interaction Center, Atlanta, GA, USA; Clinical Biomarkers Laboratory, Department of Medicine, Emory University, Atlanta, GA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14384221173006
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http://dx.doi.org/10.1016/j.ijmm.2017.09.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698147PMC
December 2017

High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies.

Authors:
Fadi F Hamdan Candace T Myers Patrick Cossette Philippe Lemay Dan Spiegelman Alexandre Dionne Laporte Christina Nassif Ousmane Diallo Jean Monlong Maxime Cadieux-Dion Sylvia Dobrzeniecka Caroline Meloche Kyle Retterer Megan T Cho Jill A Rosenfeld Weimin Bi Christine Massicotte Marguerite Miguet Ledia Brunga Brigid M Regan Kelly Mo Cory Tam Amy Schneider Georgie Hollingsworth David R FitzPatrick Alan Donaldson Natalie Canham Edward Blair Bronwyn Kerr Andrew E Fry Rhys H Thomas Joss Shelagh Jane A Hurst Helen Brittain Moira Blyth Robert Roger Lebel Erica H Gerkes Laura Davis-Keppen Quinn Stein Wendy K Chung Sara J Dorison Paul J Benke Emily Fassi Nicole Corsten-Janssen Erik-Jan Kamsteeg Frederic T Mau-Them Ange-Line Bruel Alain Verloes Katrin Õunap Monica H Wojcik Dara V F Albert Sunita Venkateswaran Tyson Ware Dean Jones Yu-Chi Liu Shekeeb S Mohammad Peyman Bizargity Carlos A Bacino Vincenzo Leuzzi Simone Martinelli Bruno Dallapiccola Marco Tartaglia Lubov Blumkin Klaas J Wierenga Gabriela Purcarin James J O'Byrne Sylvia Stockler Anna Lehman Boris Keren Marie-Christine Nougues Cyril Mignot Stéphane Auvin Caroline Nava Susan M Hiatt Martina Bebin Yunru Shao Fernando Scaglia Seema R Lalani Richard E Frye Imad T Jarjour Stéphanie Jacques Renee-Myriam Boucher Emilie Riou Myriam Srour Lionel Carmant Anne Lortie Philippe Major Paola Diadori François Dubeau Guy D'Anjou Guillaume Bourque Samuel F Berkovic Lynette G Sadleir Philippe M Campeau Zoha Kibar Ronald G Lafrenière Simon L Girard Saadet Mercimek-Mahmutoglu Cyrus Boelman Guy A Rouleau Ingrid E Scheffer Heather C Mefford Danielle M Andrade Elsa Rossignol Berge A Minassian Jacques L Michaud

Am J Hum Genet 2017 Nov;101(5):664-685

Centre Hospitalier Universitaire Sainte-Justine Research Center, Montreal, QC H3T1C5, Canada; Department of Neurosciences, Université de Montréal, Montreal, QC H3T1J4, Canada; Department of Pediatrics, Université de Montréal, Montreal, QC H3T1C5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673604PMC
November 2017

Low-level maternal exposure to nicotine associates with significant metabolic perturbations in second-trimester amniotic fluid.

Environ Int 2017 10 30;107:227-234. Epub 2017 Jul 30.

Department of Human Genetics, School of Medicine, Emory University, Whitehead Biomedical Research Building, Suite 301, 615 Michael Street, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.envint.2017.07.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569895PMC
October 2017

Corrigendum to "Plasma metabolomics in adults with cystic fibrosis during a pulmonary exacerbation: A pilot randomized study of high-dose vitamin D administration" [Metabolism vol. 70, May 2017, pages 31-41].

Metabolism 2017 09 26;74:41-42. Epub 2017 Apr 26.

Division of Endocrinology, Metabolism & Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA; Center for Cystic Fibrosis and Airways Disease Research, Children's Healthcare of Atlanta, Atlanta, GA, USA; Section of Endocrinology, Atlanta Veterans Affairs Medical Center, Atlanta, GA, USA.

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http://dx.doi.org/10.1016/j.metabol.2017.04.009DOI Listing
September 2017

Bildgebende Differenzierung Duraler Sinusvenenzysten und Thrombosen – Charakteristische Bildmerkmale.

Rofo 2017 09 11;189(9):877-879. Epub 2017 Jul 11.

Faculty of Medicine, University of Tasmania, Hobart, Australia.

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http://dx.doi.org/10.1055/s-0043-114667DOI Listing
September 2017

Metabolic Profiles of Obesity in American Indians: The Strong Heart Family Study.

PLoS One 2016 19;11(7):e0159548. Epub 2016 Jul 19.

Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159548PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951134PMC
July 2017

Metabolomics of fescue toxicosis in grazing beef steers.

Food Chem Toxicol 2017 Jul 18;105:285-299. Epub 2017 Apr 18.

Interdisciplinary Toxicology Program, University of Georgia, Athens, GA, USA; Department of Physiology and Pharmacology, University of Georgia, Athens, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.fct.2017.04.020DOI Listing
July 2017

A Small Molecule Solution to the Vexing Problem of Restenosis: Predicting Restenosis.

JACC Cardiovasc Interv 2017 07;10(13):1317-1319

Pulmonary Division, Department of Medicine, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1016/j.jcin.2017.05.044DOI Listing
July 2017

Redox theory of aging: implications for health and disease.

Clin Sci (Lond) 2017 Jul 30;131(14):1669-1688. Epub 2017 Jun 30.

Division of Pulmonary Medicine, Department of Medicine, Emory University, Atlanta, GA 30322, U.S.A.

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http://dx.doi.org/10.1042/CS20160897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773128PMC
July 2017

Oxidative Stress.

Annu Rev Biochem 2017 06 24;86:715-748. Epub 2017 Apr 24.

Department of Medicine, Emory University, Atlanta, Georgia 30322; email:

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http://dx.doi.org/10.1146/annurev-biochem-061516-045037DOI Listing
June 2017

High-resolution metabolomics to identify urine biomarkers in corticosteroid-resistant asthmatic children.

J Allergy Clin Immunol 2017 May 19;139(5):1518-1524.e4. Epub 2016 Sep 19.

Department of Medicine, Emory University, Atlanta, Ga.

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http://dx.doi.org/10.1016/j.jaci.2016.08.018DOI Listing
May 2017

Cadmium stimulates myofibroblast differentiation and mouse lung fibrosis.

Toxicology 2017 05 21;383:50-56. Epub 2017 Mar 21.

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, GA 30322, United States. Electronic address:

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http://dx.doi.org/10.1016/j.tox.2017.03.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5470547PMC
May 2017

Plasma metabolomics in adults with cystic fibrosis during a pulmonary exacerbation: A pilot randomized study of high-dose vitamin D administration.

Metabolism 2017 May 11;70:31-41. Epub 2017 Feb 11.

Division of Endocrinology, Metabolism & Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA, USA; Center for Cystic Fibrosis and Airways Disease Research, Children's Healthcare of Atlanta, Atlanta, GA, USA; Section of Endocrinology, Atlanta Veterans Affairs Medical Center, Atlanta, GA, USA.

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http://dx.doi.org/10.1016/j.metabol.2017.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5407388PMC
May 2017

Metabolic Phenotypes of Response to Vaccination in Humans.

Cell 2017 May 11;169(5):862-877.e17. Epub 2017 May 11.

Emory Vaccine Center, Yerkes National Primate Research Center, 954 Gatewood Road, Atlanta, GA 30329, USA; Department of Pathology, School of Medicine, Emory University, Atlanta, GA 30329, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.04.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5711477PMC
May 2017

From the Cover: Manganese Stimulates Mitochondrial H2O2 Production in SH-SY5Y Human Neuroblastoma Cells Over Physiologic as well as Toxicologic Range.

Toxicol Sci 2017 01 4;155(1):213-223. Epub 2016 Oct 4.

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, Georgia 30322

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http://dx.doi.org/10.1093/toxsci/kfw196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216654PMC
January 2017

xMSannotator: An R Package for Network-Based Annotation of High-Resolution Metabolomics Data.

Anal Chem 2017 01 4;89(2):1063-1067. Epub 2017 Jan 4.

Clinical Biomarkers Laboratory, Department of Medicine, Emory University , Atlanta, Georgia 30308, United States.

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http://dx.doi.org/10.1021/acs.analchem.6b01214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5447360PMC
January 2017

Redox dynamics of manganese as a mitochondrial life-death switch.

Biochem Biophys Res Commun 2017 01 3;482(3):388-398. Epub 2017 Feb 3.

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2016.10.126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5382988PMC
January 2017

Computational Metabolomics: A Framework for the Million Metabolome.

Chem Res Toxicol 2016 12 12;29(12):1956-1975. Epub 2016 Oct 12.

Clinical Biomarkers Laboratory, Department of Medicine, Emory University , Atlanta, Georgia 30322, United States.

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http://dx.doi.org/10.1021/acs.chemrestox.6b00179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5376098PMC
December 2016

Exposure Memory and Lung Regeneration.

Ann Am Thorac Soc 2016 12;13 Suppl 2:S452-S461

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Clinical Biomarkers Laboratory, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1513/AnnalsATS.201602-114AWDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5291469PMC
December 2016

Metabolic pathways of lung inflammation revealed by high-resolution metabolomics (HRM) of H1N1 influenza virus infection in mice.

Am J Physiol Regul Integr Comp Physiol 2016 11 24;311(5):R906-R916. Epub 2016 Aug 24.

Division of Pulmonary Medicine, Department of Medicine, Emory University, Atlanta, Georgia; and

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http://dx.doi.org/10.1152/ajpregu.00298.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5243214PMC
November 2016

Nuclear Thioredoxin-1 Overexpression Attenuates Alcohol-Mediated Nrf2 Signaling and Lung Fibrosis.

Alcohol Clin Exp Res 2016 09 20;40(9):1846-56. Epub 2016 Jul 20.

Division of Pulmonary, Allergy & Critical Care, Department of Medicine, Atlanta, Georgia.

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http://dx.doi.org/10.1111/acer.13148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108489PMC
September 2016

Inhibition of ileal bile acid uptake protects against nonalcoholic fatty liver disease in high-fat diet-fed mice.

Sci Transl Med 2016 09;8(357):357ra122

Department of Pediatrics, Emory University School of Medicine, 1760 Haygood Drive Northeast, Atlanta, GA 30322, USA. Children's Healthcare of Atlanta, 2015 Uppergate Drive Northeast, Atlanta, GA 30322, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5056562PMC
http://dx.doi.org/10.1126/scitranslmed.aaf4823DOI Listing
September 2016

The Exposome: A New Frontier for Education.

Am Biol Teach 2016 09;78(7):542-548

Division of Pulmonary, Allergy and Critical Care Medicine, School of Medicine, Emory University, Atlanta, GA.

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http://dx.doi.org/10.1525/abt.2016.78.7.542DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578422PMC
September 2016

Metabolic Pathways and Networks Associated With Tobacco Use in Military Personnel.

J Occup Environ Med 2016 08;58(8 Suppl 1):S111-6

Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, Emory School of Medicine, Atlanta, Georgia (Dr Jones, Mr Walker, Drs Uppal, Go); Department of Civil and Environmental Engineering, Tufts University, Medford, Massachusetts (Mr Walker); 779th Aerospace Medicine Squadron, 79th Medical Wing, Joint Base Andrews (Dr Rohrbeck); and Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 (Dr Mallon).

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http://dx.doi.org/10.1097/JOM.0000000000000763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978145PMC
August 2016

Deployment-Associated Exposure Surveillance With High-Resolution Metabolomics.

J Occup Environ Med 2016 08;58(8 Suppl 1):S12-21

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, Georgia (Mr Walker, Drs Uppal, Go, Jones); Department of Civil and Environmental Engineering, Tufts University, Medford, Massachusetts (Mr Walker, Dr Pennell); Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 (Dr Mallon); Center for Air Resources Engineering and Science, Clarkson University, Potsdam, New York (Dr Hopke); and 779th Aerospace Medicine Squadron, 79th Medical Wing, Joint Base Andrews, MD (Dr Rohrbeck).

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http://dx.doi.org/10.1097/JOM.0000000000000768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978191PMC
August 2016

Introduction to Department of Defense Research on Burn Pits, Biomarkers, and Health Outcomes Related to Deployment in Iraq and Afghanistan.

J Occup Environ Med 2016 08;58(8 Suppl 1):S3-S11

Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 (Dr Mallon); 779th Aerospace Medical Squadron, 79th Medical WingJoint Base Andrews, Maryland (Dr Rohrbeck); Bioenvironmental Engineering Flight Commander, 30th Medical Group, 338 South Dakota Ave, Vandenberg AFB, CA 93437 (Maj Haines); Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, Atlanta, Georgia (Dr Jones, Mr Walker); Departments of Medicine and Environmental Medicine, University of Rochester Medical Center (Drs Utell, Phipps, Thatcher, Woeller); Center for Air Resources Engineering and Science, Institute for a Sustainable Environment, Clarkson University, Potsdam, New York (Dr Hopke); U.S Army Center for Public Health (Provisional), Aberdeen Proving Ground (Drs Baird, Gaydos); and Anatomy and Cell Biology, Uniformed Services University, Bethesda, Maryland (Drs Pollard, Dalgard).

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http://dx.doi.org/10.1097/JOM.0000000000000775DOI Listing
August 2016

Pilot Metabolome-Wide Association Study of Benzo(a)pyrene in Serum From Military Personnel.

J Occup Environ Med 2016 08;58(8 Suppl 1):S44-52

Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, Emory University, Atlanta, Georgia (Mr Walker, Drs Uppal and Jones); Department of Civil and Environmental Engineering, Tufts University, Medford, Massachusetts (Mr Walker, Dr Pennell); Center for Air Resources Engineering and Science, Clarkson University, Potsdam (Drs Xia, Hopke); Pulmonary Division, Department of Medicine (Drs Utell, Phipps, Sime), Department of Environmental Medicine, University of Rochester Medical Center, New York (Drs Utell, Phipps, Sime); 779th Aerospace Medicine Squadron, 79th Medical Wing, Joint Base Andrews, MD (Dr Rohrbeck); and Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 (Dr Mallon).

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http://dx.doi.org/10.1097/JOM.0000000000000772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837056PMC
August 2016

High-Resolution Metabolomics Assessment of Military Personnel: Evaluating Analytical Strategies for Chemical Detection.

J Occup Environ Med 2016 08;58(8 Suppl 1):S53-61

Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, Emory School of Medicine, Atlanta, Georgia (Mr Liu, Mr Walker, Dr Uppal, Tran, Dr Jones); Department of Civil and Environmental Engineering, Tufts University, Medford, Massachusetts (Mr Walker); 779th Aerospace Medicine Squadron, 79th Medical Wing, Joint Base Andrews, MD (Dr Rohrbeck); and Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 (Dr Mallon).

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http://dx.doi.org/10.1097/JOM.0000000000000773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978147PMC
August 2016

High-Resolution Metabolomics for Nutrition and Health Assessment of Armed Forces Personnel.

J Occup Environ Med 2016 08;58(8 Suppl 1):S80-8

Clinical Biomarkers Laboratory, Division of Pulmonary, Allergy, and Critical Care Medicine, Emory School of Medicine, Atlanta, Georgia (Dr Accardi, Mr Walker, Drs Uppal, Jones); Department of Civil and Environmental Engineering, Tufts University, Medford, Massachusetts (Mr Walker, Dr Pennell); Division of Cardiology, Emory School of Medicine, Atlanta, Georgia (Dr Quyyumi); 779th Aerospace Medicine Squadron, 79th Medical Wing, Joint Base Andrews (Dr Rohrbeck); and Professor, Department of Preventive Medicine and Biostatistics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814 (Dr Mallon).

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http://dx.doi.org/10.1097/JOM.0000000000000770DOI Listing
August 2016

Low-dose oral cadmium increases airway reactivity and lung neuronal gene expression in mice.

Physiol Rep 2016 Jul;4(13)

Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Emory University, Atlanta, Georgia

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http://dx.doi.org/10.14814/phy2.12821DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945833PMC
July 2016

Hydrogen peroxide and central redox theory for aerobic life: A tribute to Helmut Sies: Scout, trailblazer, and redox pioneer.

Authors:
Dean P Jones

Arch Biochem Biophys 2016 Apr;595:13-8

Department of Medicine, Emory University, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2015.10.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4838774PMC
April 2016