Dean Fergusson

Dean Fergusson

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Dean Fergusson

Publications by authors named "Dean Fergusson"

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Prognostic Value of Glial Fibrillary Acidic Protein in Patients With Moderate and Severe Traumatic Brain Injury: A Systematic Review and Meta-Analysis.

Crit Care Med 2019 Jun;47(6):e522-e529

CHU de Québec - Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma - Emergency - Critical Care Medicine), Université Laval, Québec City, QC, Canada.

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http://dx.doi.org/10.1097/CCM.0000000000003728DOI Listing
June 2019

There is still a place for significance testing in clinical trials.

Clin Trials 2019 May 9:1740774519846504. Epub 2019 May 9.

4 Epidemiology & Biostatistics, Memorial Sloan Kettering Cancer Institution, New York, NY, USA.

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http://dx.doi.org/10.1177/1740774519846504DOI Listing
May 2019

De-escalation of bone-modifying agents in patients with bone metastases from breast cancer: a systematic review and meta-analysis.

Breast Cancer Res Treat 2019 May 11. Epub 2019 May 11.

Division of Medical Oncology, The Ottawa Hospital Cancer Centre, 501 Smyth Road, Box 912, Ottawa, ON, K1H 8L6, Canada.

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http://dx.doi.org/10.1007/s10549-019-05265-1DOI Listing
May 2019

Risks and Benefits of Chimeric Antigen Receptor T-Cell (CAR-T) Therapy in Cancer: A Systematic Review and Meta-Analysis.

Transfus Med Rev 2019 Apr 14;33(2):98-110. Epub 2019 Feb 14.

Department of Anesthesiology and Pain Medicine, The Ottawa Hospital, Ottawa, Ontario, Canada; Clinical Epidemiology Program, Blueprint Translational Research Group, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada; Regenerative Medicine Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.tmrv.2019.01.005DOI Listing
April 2019

Direct oral anticoagulants in treatment of cerebral venous thrombosis: a systematic review protocol.

Syst Rev 2019 Apr 18;8(1):99. Epub 2019 Apr 18.

Department of Medicine, University of Ottawa and The Ottawa Hospital Research Institute, 1053 Carling Avenue, Ottawa, ON, K1Y 4E9, Canada.

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http://dx.doi.org/10.1186/s13643-019-1022-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6474061PMC
April 2019

Red blood cell transfusion in critically ill patients with traumatic brain injury: an international survey of physicians' attitudes.

Can J Anaesth 2019 Apr 22. Epub 2019 Apr 22.

CHU de Québec - Université Laval Research Center, Population Health and Optimal Health Practices Research Unit, Traumatology - Emergency - Critical Care Medicine, CHU de Québec-Université Laval (Hôpital de l'Enfant-Jésus), 1401, 18e rue, Québec City, QC, G1J 1Z4, Canada.

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http://dx.doi.org/10.1007/s12630-019-01369-wDOI Listing
April 2019

Can authorship bias be detected in meta-analysis?

Can J Anaesth 2019 Mar 6;66(3):287-292. Epub 2019 Feb 6.

George and Fay Yee Centre for Healthcare Innovation, University of Manitoba/Winnipeg Regional Health Authority, Chown Building, 367-753 McDermot Ave, Winnipeg, MB, R3A 1R9, Canada.

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http://dx.doi.org/10.1007/s12630-018-01268-6DOI Listing
March 2019

Letter From the Guest Editors.

Semin Nucl Med 2019 03 7;49(2):85-86. Epub 2018 Dec 7.

Department of Medicine, Division of Nuclear Medicine, University of Ottawa, Ottawa, ON, Canada.

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http://dx.doi.org/10.1053/j.semnuclmed.2018.11.002DOI Listing
March 2019

Diagnostic Accuracy Studies.

Semin Nucl Med 2019 03 13;49(2):87-93. Epub 2018 Dec 13.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1053/j.semnuclmed.2018.11.005DOI Listing
March 2019

Regenerative cell therapy for pulmonary arterial hypertension in animal models: a systematic review.

Stem Cell Res Ther 2019 Mar 6;10(1):75. Epub 2019 Mar 6.

Regenerative Medicine Program, The Ottawa Hospital Research Institute, 501 Smyth Road, PO Box 201B, Ottawa, ON, K1H 8L6, Canada.

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http://dx.doi.org/10.1186/s13287-019-1172-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404277PMC
March 2019

Trends and outcomes in multicomponent blood transfusion: an 11-year cohort study of a large multisite academic center.

Transfusion 2019 Mar 22. Epub 2019 Mar 22.

Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/trf.15260
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http://dx.doi.org/10.1111/trf.15260DOI Listing
March 2019

Physician Survey of Timing of Adjuvant Endocrine Therapy Relative to Radiotherapy in Early Stage Breast Cancer Patients.

Clin Breast Cancer 2019 Feb 4;19(1):e40-e47. Epub 2018 Sep 4.

Department of Medicine and Division of Medical Oncology, The Ottawa Hospital and University of Ottawa, Ottawa, Canada; The Ottawa Hospital Research Institute, Ottawa, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.clbc.2018.08.012DOI Listing
February 2019

Prolonged versus brief balloon inflation during arterial angioplasty for de novo atherosclerotic disease: protocol for a systematic review.

Syst Rev 2019 Feb 5;8(1):45. Epub 2019 Feb 5.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, K1H8L6, Canada.

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http://dx.doi.org/10.1186/s13643-019-0955-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6362580PMC
February 2019

Assessment of Pregabalin Postapproval Trials and the Suggestion of Efficacy for New Indications: A Systematic Review.

JAMA Intern Med 2019 Jan;179(1):90-97

Studies of Translation, Ethics, and Medicine, Biomedical Ethics Unit, McGill University, Montreal, Quebec, Canada.

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http://archinte.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamainternmed.2018.5705DOI Listing
January 2019

Interventions to improve resilience in physicians who have completed training: A systematic review.

PLoS One 2019 17;14(1):e0210512. Epub 2019 Jan 17.

Department of Medicine, University of Ottawa and The Ottawa Hospital, Ottawa, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210512PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336384PMC
January 2019

Evaluating the predictive capabilities of haematoma expansion scores in patients with acute intracerebral haemorrhage: protocol for a scoping review.

BMJ Open 2019 Jan 21;9(1):e024744. Epub 2019 Jan 21.

Ottawa Stroke Program, The Ottawa Hospital: Division of Neurology, University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1136/bmjopen-2018-024744DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347899PMC
January 2019

Effectiveness of Outpatient Versus Operating Room Hysteroscopy for the Diagnosis and Treatment of Uterine Conditions: A Systematic Review and Meta-Analysis.

J Obstet Gynaecol Can 2018 Dec 6. Epub 2018 Dec 6.

School of Epidemiology and Public Health, University of Ottawa, Ottawa, ON; Department of Obstetrics, Gynecology, and Newborn Care, Ottawa Hospital, Ottawa, ON.

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http://dx.doi.org/10.1016/j.jogc.2018.10.002DOI Listing
December 2018

Protocol for treatment of Achilles tendon ruptures; a systematic review with network meta-analysis.

Syst Rev 2018 12 23;7(1):247. Epub 2018 Dec 23.

School of Epidemiology and Public Health; Clinical Epidemiology Program, Centre for Practice-Changing, The Ottawa Hospital Research Institute Research, University of Ottawa, Ottawa, Canada.

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https://systematicreviewsjournal.biomedcentral.com/articles/
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http://dx.doi.org/10.1186/s13643-018-0912-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6304227PMC
December 2018

Can We Use Administrative Data to Accurately Identify Patients Who Receive a Prostate Biopsy?

JCO Clin Cancer Inform 2018 12;2:1-10

Luke T. Lavallée, Rodney H. Breau, Cynthia Walsh, and Carl van Walraven, The Ottawa Hospital and University of Ottawa; Luke T. Lavallée, Rodney H. Breau, Dean Fergusson, and Carl van Walraven, Ottawa Hospital Research Institute; and Luke T. Lavallée and Carl van Walraven, Institute for Clinical Evaluative Sciences, Ottawa, ON, Canada.

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http://ascopubs.org/doi/10.1200/CCI.17.00143
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http://dx.doi.org/10.1200/CCI.17.00143DOI Listing
December 2018

Demonstrating the value of patient-oriented research in Ontario.

CMAJ 2018 Nov;190(Suppl):S53-S54

The Ottawa Methods Centre, Clinical Epidemiology Program (Fergusson, Monfaredi), The Ottawa Hospital Research Institute; Faculty of Medicine (Fergusson), University of Ottawa, Ottawa, Ont.

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http://dx.doi.org/10.1503/cmaj.180812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472448PMC
November 2018

Stakeholder views regarding ethical issues in the design and conduct of pragmatic trials: study protocol.

BMC Med Ethics 2018 11 20;19(1):90. Epub 2018 Nov 20.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, Civic Campus, 1053 Carling Avenue, Civic Box 693, Admin Services Building, ASB 2-013, Ottawa, ON, K1Y 4E9, Canada.

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http://dx.doi.org/10.1186/s12910-018-0332-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247737PMC
November 2018

Choosing the target difference and undertaking and reporting the sample size calculation for a randomised controlled trial - the development of the DELTA guidance.

Trials 2018 Oct 10;19(1):542. Epub 2018 Oct 10.

Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Botnar Research Centre, Nuffield Orthopaedic Centre, Windmill Rd, Oxford, OX3 7LD, UK.

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http://dx.doi.org/10.1186/s13063-018-2887-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180499PMC
October 2018

The Effectiveness of Tranexamic Acid at Reducing Blood Loss and Transfusion Requirement for Women Undergoing Myomectomy: A Systematic Review and Meta-analysis.

J Obstet Gynaecol Can 2018 Oct 29. Epub 2018 Oct 29.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, ON; Department of Obstetrics and Gynecology, University of Ottawa, Ottawa, ON. Electronic address:

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http://dx.doi.org/10.1016/j.jogc.2018.04.007DOI Listing
October 2018

Thinking clearly about the FIRST trial: addressing ethical challenges in cluster randomised trials of policy interventions involving health providers.

J Med Ethics 2018 Sep 27;44(9):593-598. Epub 2018 Apr 27.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1136/medethics-2017-104282DOI Listing
September 2018

Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery.

N Engl J Med 2018 09 26;379(13):1224-1233. Epub 2018 Aug 26.

From the Department of Anesthesia (C.D.M., G.M.T.H., N.M.) and the Department of Surgery, Division of Cardiac Surgery (S.V.), St. Michael's Hospital, Keenan Research Centre for Biomedical Science, the Li Ka Shing Knowledge Institute of St. Michael's Hospital (C.D.M., G.M.T.H., K.T., S.V., P.J.), Applied Health Research Centre (J.H., D.D., K.T., S.V., P.J.), Sunnybrook Health Sciences Centre (S.F.), Division of Hematology, Mount Sinai Hospital (N.S.), the Departments of Medicine (P.J., N.S.), Physiology (C.D.M., G.M.T.H), and Laboratory Medicine and Pathobiology (N.S.), Dalla Lana School of Public Health (K.T.), and Institute of Health Policy, Management and Evaluation, University of Toronto, and Canadian Blood Services (N.S.), Toronto, the Population Health Research Institute (R.P.W., E.B.-C.), Hamilton Health Sciences Center (R.P.W., E.B.-C., K.C., S.S.), McMaster University (R.P.W., E.B.-C., K.C., S.S.), Hamilton, ON, the Ottawa Hospital Research Institute, University of Ottawa, Ottawa (D.A.F.), the Cumming School of Medicine and Libin Cardiovascular Institute, University of Calgary, Calgary (A.J.G.), and the Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton (S.M.B.), CHUS-Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke (É.M.), and the Department of Anesthesiology and Critical Care Medicine, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Laval (F.L.), QC, the Departments of Anesthesia and Medicine, Division of Critical Care, Centre Hospitalier de l'Université de Montréal, Montreal (F.M.C.), and the Department of Anesthesia, Perioperative and Pain Medicine, St. Boniface Hospital, University of Manitoba, Winnipeg (H.P.G.) - all in Canada; the Department of Cardiothoracic Anesthesia, Rigshospitalet, Copenhagen University Hospital, Copenhagen (B.K.); Medical Research Institute of New Zealand, Wellington (S.M., P.J.Y.), and Waikato Hospital, Hamilton (K.B.) - both in New Zealand; Fundación Cardioinfantil-Instituto de Cardiología and Universidad Autónoma de Bucaramanga, Bucaramanga, Colombia (J.C.V.); the Department of Surgery, University of Melbourne (A.R., C.R.), and the Department of Anaesthesia and Pain Management, Royal Melbourne Hospital (C.R.), Melbourne, VIC, and the Department of Anaesthesia, Royal Adelaide Hospital, and the Discipline of Acute Care Medicine, University of Adelaide, Adelaide, SA (T.W.P.) - all in Australia; University of Basel, Department of Anesthesia, Surgical Intensive Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Basel, and Klinik Hirslanden Zurich, Zurich - both in Switzerland (M.D.S.); Heart Care Associates, SAL Hospital, Gujarat, India (C.M.); and the Department of Cardiothoracic Anaesthesia, National Heart Center, and the Department of Anaesthesiology, Singapore General Hospital - both in Singapore (N.-C.H.).

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http://dx.doi.org/10.1056/NEJMoa1808561DOI Listing
September 2018

Primary Febrile Neutropenia Prophylaxis for Patients Who Receive FEC-D Chemotherapy for Breast Cancer: A Systematic Review.

J Glob Oncol 2018 Sep 21;4:1-8. Epub 2017 Apr 21.

Ricardo Fernandes, Mohamed F.K. Ibrahim, Shaan Dudani, Kirstin Perdrizet, Habeeb Majeed, and Risa Shorr, The Ottawa Hospital; Ricardo Fernandes, Shaan Dudani, Kirstin Perdrizet, Habeeb Majeed, Brian Hutton, Dean Fergusson, and Mark Clemons, University of Ottawa; Sasha Mazzarello, Carol Stober, Lisa Vandermeer, Brian Hutton, Dean Fergusson, and Mark Clemons, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada; and Bishal Gyawali, Nobel Hospital, Sinamangal, Kathmandu, Nepal.

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http://dx.doi.org/10.1200/JGO.2016.008540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6180804PMC
September 2018

Age of transfused blood in critically ill adult trauma patients: a prespecified nested analysis of the Age of Blood Evaluation randomized trial.

Transfusion 2018 08 19;58(8):1846-1854. Epub 2018 Apr 19.

CHU de Québec-Université Laval Research Center, Population Health and Optimal Health Practices Unit (Trauma-Emergency-Critical Care Medicine), Université Laval, Québec City, Quebec, Canada.

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http://dx.doi.org/10.1111/trf.14640DOI Listing
August 2018

Personal goal-setting among women living with breast cancer: protocol for a scoping review.

Syst Rev 2018 08 28;7(1):132. Epub 2018 Aug 28.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa Canada and School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Canada.

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http://dx.doi.org/10.1186/s13643-018-0794-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6114874PMC
August 2018

Filgrastim use in patients receiving chemotherapy for early-stage breast cancer-a survey of physicians and patients.

Support Care Cancer 2018 Jul 6;26(7):2323-2331. Epub 2018 Feb 6.

Department of Medicine, Division of Medical Oncology, The Ottawa Hospital and University of Ottawa, Ottawa, Canada.

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http://dx.doi.org/10.1007/s00520-018-4074-8DOI Listing
July 2018

Case Mix, Patterns of Care, and Inpatient Outcomes Among Ontario Kidney Transplant Centers: A Population-Based Study.

Can J Kidney Health Dis 2018 17;5:2054358117730053. Epub 2018 Jul 17.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ontario, Canada.

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http://dx.doi.org/10.1177/2054358117730053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050611PMC
July 2018

Hemoglobin thresholds and red blood cell transfusion in adult patients with moderate or severe traumatic brain injuries: A retrospective cohort study.

J Crit Care 2018 06 31;45:133-139. Epub 2018 Jan 31.

CHU de Québec - Université Laval Research Center, Population Health and Optimal Health Practices Research Unit (Trauma - Emergency - Critical Care Medicine), Université Laval, Z-207, 1401, 18e rue, Québec, QC G1J 1Z4, Canada; Department of Anesthesiology and Critical Care Medicine, Division of Critical Care Medicine, Université Laval, 1050, avenue de la Médecine, Québec, QC G1V 0A6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2018.01.023DOI Listing
June 2018

Antipsychotics for treatment of delirium in hospitalised non-ICU patients.

Cochrane Database Syst Rev 2018 06 18;6:CD005594. Epub 2018 Jun 18.

Department of Pharmacy, Mount Sinai Hospital, Leslie Dan Faculty of Pharmacy, University of Toronto, 600 University Avenue, Room 18-377, Toronto, ON, Canada, M5G 1X5.

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http://dx.doi.org/10.1002/14651858.CD005594.pub3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6513380PMC
June 2018

The Efficacy of Postoperative Iron Therapy in Improving Clinical and Patient-Centered Outcomes Following Surgery: A Systematic Review and Meta-Analysis.

Transfus Med Rev 2018 04 22;32(2):89-101. Epub 2017 Oct 22.

University of Ottawa, Ottawa, Ontario, Canada; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.tmrv.2017.10.002DOI Listing
April 2018

Current practices in perioperative blood management for patients undergoing liver resection: a survey of surgeons and anesthesiologists.

Transfusion 2018 03 10;58(3):781-787. Epub 2018 Jan 10.

Liver and Pancreas Unit, Department of Surgery, University of Ottawa, Ontario.

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http://dx.doi.org/10.1111/trf.14465DOI Listing
March 2018

The efficacy and safety of topical tranexamic acid: A systematic review and meta-analysis.

Transfus Med Rev 2018 Feb 19. Epub 2018 Feb 19.

Clinical Epidemiology Program, Centre for Practice Changing Research, Ottawa Hospital Research Institute, Ottawa, ON, Canada; Division of Urology, Department of Surgery, The Ottawa Hospital, Ottawa, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.tmrv.2018.02.003DOI Listing
February 2018

Red blood cell transfusion in adult palliative care: a systematic review.

Transfusion 2018 01 1;58(1):233-241. Epub 2017 Dec 1.

Department of Medicine, University of Ottawa/The Ottawa Hospital.

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http://doi.wiley.com/10.1111/trf.14413
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http://dx.doi.org/10.1111/trf.14413DOI Listing
January 2018

Delirium and exposure to psychoactive medications in critically ill adults: A multi-centre observational study.

J Crit Care 2017 12 5;42:268-274. Epub 2017 Aug 5.

Department of Critical Care Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2017.08.003DOI Listing
December 2017

The Prognostic Value of MRI in Moderate and Severe Traumatic Brain Injury: A Systematic Review and Meta-Analysis.

Crit Care Med 2017 Dec;45(12):e1280-e1288

CHU de Québec - Université Laval Research Centre, Population Health and Optimal Health Practices Research Unit (Trauma-Emergency-Critical Care Medicine), Université Laval, Québec, QC, Canada.

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http://dx.doi.org/10.1097/CCM.0000000000002731DOI Listing
December 2017

Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol.

Syst Rev 2017 11 7;6(1):226. Epub 2017 Nov 7.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, Department of Medicine (Division of Critical Care), University of Ottawa, 501 Smyth Rd, Box 201, Ottawa, ON, K1H 8L6, Canada.

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http://dx.doi.org/10.1186/s13643-017-0601-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5688817PMC
November 2017

Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery.

N Engl J Med 2017 11 12;377(22):2133-2144. Epub 2017 Nov 12.

From the Department of Anesthesia (C.D.M., G.M.T.H.) and the Department of Surgery, Division of Cardiac Surgery (S.V.), Keenan Research Centre for Biomedical Science and Li Ka Shing Knowledge Institute of St. Michael's Hospital, Applied Health Research Centre (AHRC), Li Ka Shing Knowledge Institute of St. Michael's Hospital (J.H., A.C.), Sunnybrook Health Sciences Center (S.F.), AHRC, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Dalla Lana School of Public Health (K.E.T.), and AHRC, Li Ka Shing Knowledge Institute of St. Michael's Hospital, Department of Medicine and Institute of Health Policy, Management and Evaluation (P.J.), University of Toronto, and the Departments of Medicine, Laboratory Medicine, and Pathobiology, Institute of Health Policy, Management, and Evaluation, University of Toronto, and the Division of Hematology, Mount Sinai Hospital, Canadian Blood Services (N.S.), Toronto, Population Health Research Institute (R.P.W., E.B.-C.), Hamilton Health Sciences Centre (R.P.W., E.B.-C., K.C.), and McMaster University (R.P.W., E.B.-C., S.S.), Hamilton, ON, Ottawa Hospital Research Institute, University of Ottawa, Ottawa (D.A.F.), the Department of Anesthesia, Foothills Medical Centre, University of Calgary, Calgary, AB (A.J.G.), Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC (É.M.), the Departments of Anesthesia and Medicine, Division of Critical Care, Centre Hospitalier de l'Université de Montréal, Montreal (F.M.C.), the Departments of Anesthesia and Surgery, University of Manitoba, St. Boniface Hospital, Winnipeg (H.P.G.), the Department of Anesthesiology and Critical Care Medicine, Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Laval, QC (F.L.), and the Department of Critical Care Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton (S.M.B.) - all in Canada; the Department of Cardiothoracic Anesthesia, Rigshospitalet, Copenhagen University Hospital, Copenhagen (B.K.); Medical Research Institute of New Zealand, Wellington (S.M., P.J.Y.), and Waikato Hospital, Hamilton (K.B.) - both in New Zealand; the Department of Surgery, University of Melbourne (A.R., C.R.), and the Department of Anaesthesia and Pain Management, Royal Melbourne Hospital (C.R.), Melbourne, VIC, and the Department of Anaesthesia, Royal Adelaide Hospital, Discipline of Acute Care Medicine, University of Adelaide, Adelaide, SA (T.W.P.) - all in Australia; Fundación Cardioinfantil-Instituto de Cardiología, Bogota, and Universidad Autónoma de Bucaramanga, Bucaramanga - both in Colombia (J.C.V.); the University of Basel, Department of Anesthesia, Surgical Intensive Care, Prehospital Emergency Medicine and Pain Therapy, University Hospital Basel, Basel, and Klinik Hirslanden, Zurich - both in Switzerland (M.D.S.); the Department of Cardiothoracic Anesthesia, National Heart Center, and the Department of Anesthesiology, Singapore General Hospital, Singapore (N.C.H.); and Heart Care Associates, Ahmedabad, India (C.M.).

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http://dx.doi.org/10.1056/NEJMoa1711818DOI Listing
November 2017

Vitamin D deficiency in critically ill children: a systematic review and meta-analysis.

Crit Care 2017 Nov 23;21(1):287. Epub 2017 Nov 23.

Children's Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.

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http://dx.doi.org/10.1186/s13054-017-1875-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5701429PMC
November 2017

The Risks and Benefits of Cavernous Neurovascular Bundle Sparing during Radical Prostatectomy: A Systematic Review and Meta-Analysis.

J Urol 2017 10 9;198(4):760-769. Epub 2017 Mar 9.

Division of Urology, Department of Surgery, The Ottawa Hospital, Ottawa, Ontario, Canada; Ottawa Hospital Research Institute, Ottawa, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2017.02.3344DOI Listing
October 2017

Canadian funders and institutions are lagging on reporting results of clinical trials.

CMAJ 2017 10;189(42):E1302-E1303

Centre for Journalology, Clinical Epidemiology Program (Cobey, Fergusson, Moher), Ottawa Methods Centre, Ottawa Hospital Research Institute; School of Epidemiology, Public Health, and Preventative Medicine (Cobey, Fergusson, Moher), Faculty of Medicine, University of Ottawa, Ottawa, Ont.; Department of Psychology (Cobey), University of Stirling, Stirling, UK.

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http://dx.doi.org/10.1503/cmaj.170840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654986PMC
October 2017

Risks and trends of red blood cell transfusion in obstetric patients: a retrospective study of 45,213 deliveries using administrative data.

Transfusion 2017 09 22;57(9):2197-2205. Epub 2017 Jun 22.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1111/trf.14184DOI Listing
September 2017

A cost-utility analysis of risk model-guided versus physician's choice antiemetic prophylaxis in patients receiving chemotherapy for early-stage breast cancer: a net benefit regression approach.

Support Care Cancer 2017 08 9;25(8):2505-2513. Epub 2017 Mar 9.

Ottawa Hospital Research Institute, The Ottawa Hospital, General Campus, 501 Smyth Road, PO Box 201B, Ottawa, ON, K1H 8L6, Canada.

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http://dx.doi.org/10.1007/s00520-017-3658-zDOI Listing
August 2017

The Safety and Efficacy of Lysine Analogues in Cancer Patients: A Systematic Review and Meta-Analysis.

Transfus Med Rev 2017 07 22;31(3):141-148. Epub 2017 Mar 22.

Clinical Epidemiology Program, Centre for Practice Changing Research, Ottawa Hospital Research Institute, Ottawa, ON, Canada; Division of Urology, Department of Surgery, The Ottawa Hospital, Ottawa, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.tmrv.2017.03.002DOI Listing
July 2017

β-Trace Protein Assays: A Comparison Between Nephelometric and ELISA Methodologies.

Am J Kidney Dis 2017 06 12;69(6):866-868. Epub 2017 Apr 12.

University of Ottawa, Ottawa, Canada; Ottawa Health Research Institute, Ottawa, Canada.

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http://dx.doi.org/10.1053/j.ajkd.2017.02.371DOI Listing
June 2017

Nonpublication of trial results for new neurological drugs: A systematic review.

Ann Neurol 2017 Jun 5;81(6):782-789. Epub 2017 Jun 5.

Studies of Translation, Ethics, and Medicine (STREAM), Biomedical Ethics Unit, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/ana.24952DOI Listing
June 2017

Outcomes in a nurse-led peripherally inserted central catheter program: a retrospective cohort study.

CMAJ Open 2017 Jun;5(3):E535-E539

Affiliations: The Ottawa Hospital (McDiarmid), Ottawa Hospital Research Institute (McDiarmid, Scrivens, Sabri); Department of Medicine (Carrier), Ottawa Hospital Research Institute at the University of Ottawa; Division of Microbiology and Infectious Diseases (Toye), University of Ottawa, The Ottawa Hospital; Department of Medicine (Huebsch), University of Ottawa, The Ottawa Hospital; Clinical Epidemiology Program (Fergusson), Ottawa Hospital Research Institute; Department of Medicine (Fergusson), University of Ottawa, Ottawa, Ont.

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http://dx.doi.org/10.9778/cmajo.20170010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621949PMC
June 2017

Blood Donor Characteristics On Transfusion Outcomes-Should Obesity Be Assessed in Future Clinical Trials?-Reply.

JAMA Intern Med 2017 04;177(4):599-600

Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa, Canada.

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http://dx.doi.org/10.1001/jamainternmed.2017.0245DOI Listing
April 2017

Transfusion of red blood cells in patients with traumatic brain injuries admitted to Canadian trauma health centres: a multicentre cohort study.

BMJ Open 2017 03 29;7(3):e014472. Epub 2017 Mar 29.

Population Health and Optimal Health Practices Research Unit (Trauma-Emergency-Critical Care Medicine), CHU de Québec-Université Laval Research Centre, Université Laval, Québec, Québec, Canada.

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http://dx.doi.org/10.1136/bmjopen-2016-014472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5372060PMC
March 2017