Dawood Darbar

Dawood Darbar

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Dawood Darbar

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Electrophysiologic and molecular mechanisms of a frameshift NPPA mutation linked with familial atrial fibrillation.

J Mol Cell Cardiol 2019 Jul 8;132:24-35. Epub 2019 May 8.

Departments of Medicine, University of Illinois at Chicago, Chicago, IL, United States of America; Physiology and Biophysics, University of Illinois at Chicago, Chicago, IL, United States of America; Pharmacology, University of Illinois at Chicago, Chicago, IL, United States of America. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00222828193008
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http://dx.doi.org/10.1016/j.yjmcc.2019.05.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599642PMC
July 2019

Relation of Body Mass Index to Symptom Burden in Patients withAtrial Fibrillation.

Am J Cardiol 2018 07 1;122(2):235-241. Epub 2018 May 1.

Department of Medicine, University of Illinois at Chicago, Jesse Brown VA Medical Center, Chicago, Illinois; Departments of Medicine and Molecular Physiology and Biophysics, Vanderbilt University, Nashville, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2018.04.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6028292PMC
July 2018

Race and Socioeconomic Status Regulate Lifetime Risk of Atrial Fibrillation.

Circ Arrhythm Electrophysiol 2018 Jul;11(7):e006584

Division of Cardiology, University of Illinois at Chicago. Jesse Brown Veterans Administration, Chicago, IL.

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http://dx.doi.org/10.1161/CIRCEP.118.006584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6061964PMC
July 2018

Electrophysiologic Characterization of Calcium Handling in Human Induced Pluripotent Stem Cell-Derived Atrial Cardiomyocytes.

Stem Cell Reports 2018 06 3;10(6):1867-1878. Epub 2018 May 3.

Division of Cardiology, Department of Medicine, University of Illinois at Chicago, 840 S. Wood Street, 920S (MC 715), Chicago, IL 60612, USA; Department of Pharmacology, University of Illinois at Chicago, Chicago, IL, USA. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2018.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989733PMC
June 2018

Multi-ethnic genome-wide association study for atrial fibrillation.

Authors:
Carolina Roselli Mark D Chaffin Lu-Chen Weng Stefanie Aeschbacher Gustav Ahlberg Christine M Albert Peter Almgren Alvaro Alonso Christopher D Anderson Krishna G Aragam Dan E Arking John Barnard Traci M Bartz Emelia J Benjamin Nathan A Bihlmeyer Joshua C Bis Heather L Bloom Eric Boerwinkle Erwin B Bottinger Jennifer A Brody Hugh Calkins Archie Campbell Thomas P Cappola John Carlquist Daniel I Chasman Lin Y Chen Yii-Der Ida Chen Eue-Keun Choi Seung Hoan Choi Ingrid E Christophersen Mina K Chung John W Cole David Conen James Cook Harry J Crijns Michael J Cutler Scott M Damrauer Brian R Daniels Dawood Darbar Graciela Delgado Joshua C Denny Martin Dichgans Marcus Dörr Elton A Dudink Samuel C Dudley Nada Esa Tonu Esko Markku Eskola Diane Fatkin Stephan B Felix Ian Ford Oscar H Franco Bastiaan Geelhoed Raji P Grewal Vilmundur Gudnason Xiuqing Guo Namrata Gupta Stefan Gustafsson Rebecca Gutmann Anders Hamsten Tamara B Harris Caroline Hayward Susan R Heckbert Jussi Hernesniemi Lynne J Hocking Albert Hofman Andrea R V R Horimoto Jie Huang Paul L Huang Jennifer Huffman Erik Ingelsson Esra Gucuk Ipek Kaoru Ito Jordi Jimenez-Conde Renee Johnson J Wouter Jukema Stefan Kääb Mika Kähönen Yoichiro Kamatani John P Kane Adnan Kastrati Sekar Kathiresan Petra Katschnig-Winter Maryam Kavousi Thorsten Kessler Bas L Kietselaer Paulus Kirchhof Marcus E Kleber Stacey Knight Jose E Krieger Michiaki Kubo Lenore J Launer Jari Laurikka Terho Lehtimäki Kirsten Leineweber Rozenn N Lemaitre Man Li Hong Euy Lim Henry J Lin Honghuang Lin Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Barry London Ruth J F Loos Siew-Kee Low Yingchang Lu Leo-Pekka Lyytikäinen Peter W Macfarlane Patrik K Magnusson Anubha Mahajan Rainer Malik Alfredo J Mansur Gregory M Marcus Lauren Margolin Kenneth B Margulies Winfried März David D McManus Olle Melander Sanghamitra Mohanty Jay A Montgomery Michael P Morley Andrew P Morris Martina Müller-Nurasyid Andrea Natale Saman Nazarian Benjamin Neumann Christopher Newton-Cheh Maartje N Niemeijer Kjell Nikus Peter Nilsson Raymond Noordam Heidi Oellers Morten S Olesen Marju Orho-Melander Sandosh Padmanabhan Hui-Nam Pak Guillaume Paré Nancy L Pedersen Joanna Pera Alexandre Pereira David Porteous Bruce M Psaty Sara L Pulit Clive R Pullinger Daniel J Rader Lena Refsgaard Marta Ribasés Paul M Ridker Michiel Rienstra Lorenz Risch Dan M Roden Jonathan Rosand Michael A Rosenberg Natalia Rost Jerome I Rotter Samir Saba Roopinder K Sandhu Renate B Schnabel Katharina Schramm Heribert Schunkert Claudia Schurman Stuart A Scott Ilkka Seppälä Christian Shaffer Svati Shah Alaa A Shalaby Jaemin Shim M Benjamin Shoemaker Joylene E Siland Juha Sinisalo Moritz F Sinner Agnieszka Slowik Albert V Smith Blair H Smith J Gustav Smith Jonathan D Smith Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Bruno H Stricker Albert Sun Han Sun Jesper H Svendsen Toshihiro Tanaka Kahraman Tanriverdi Kent D Taylor Maris Teder-Laving Alexander Teumer Sébastien Thériault Stella Trompet Nathan R Tucker Arnljot Tveit Andre G Uitterlinden Pim Van Der Harst Isabelle C Van Gelder David R Van Wagoner Niek Verweij Efthymia Vlachopoulou Uwe Völker Biqi Wang Peter E Weeke Bob Weijs Raul Weiss Stefan Weiss Quinn S Wells Kerri L Wiggins Jorge A Wong Daniel Woo Bradford B Worrall Pil-Sung Yang Jie Yao Zachary T Yoneda Tanja Zeller Lingyao Zeng Steven A Lubitz Kathryn L Lunetta Patrick T Ellinor

Nat Genet 2018 06 11;50(9):1225-1233. Epub 2018 Jun 11.

Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0133-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136836PMC
June 2018

Is Achieving the American Heart Association's Life Simple 7 Goals Sufficient to Reduce the Burden of Atrial Fibrillation? No Simple Answers.

J Am Heart Assoc 2018 04 12;7(8). Epub 2018 Apr 12.

Department of Medicine and Pharmacology, University of Illinois at Chicago, IL

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http://dx.doi.org/10.1161/JAHA.118.009127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6015403PMC
April 2018

Germline versus somatic mutations in genetic atrial fibrillation.

Heart Rhythm 2017 10 20;14(10):1539-1540. Epub 2017 Jul 20.

Division of Cardiology, University of Illinois at Chicago, Chicago, Illinois. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2017.07.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705188PMC
October 2017

Genetic heterogeneity of atrial fibrillation susceptibility loci across racial or ethnic groups.

Eur Heart J 2017 09;38(34):2595-2598

Division of Cardiology, University of Illinois at Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1093/eurheartj/ehx289DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837825PMC
September 2017

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

Authors:
Ingrid E Christophersen Michiel Rienstra Carolina Roselli Xiaoyan Yin Bastiaan Geelhoed John Barnard Honghuang Lin Dan E Arking Albert V Smith Christine M Albert Mark Chaffin Nathan R Tucker Molong Li Derek Klarin Nathan A Bihlmeyer Siew-Kee Low Peter E Weeke Martina Müller-Nurasyid J Gustav Smith Jennifer A Brody Maartje N Niemeijer Marcus Dörr Stella Trompet Jennifer Huffman Stefan Gustafsson Claudia Schurmann Marcus E Kleber Leo-Pekka Lyytikäinen Ilkka Seppälä Rainer Malik Andrea R V R Horimoto Marco Perez Juha Sinisalo Stefanie Aeschbacher Sébastien Thériault Jie Yao Farid Radmanesh Stefan Weiss Alexander Teumer Seung Hoan Choi Lu-Chen Weng Sebastian Clauss Rajat Deo Daniel J Rader Svati H Shah Albert Sun Jemma C Hopewell Stephanie Debette Ganesh Chauhan Qiong Yang Bradford B Worrall Guillaume Paré Yoichiro Kamatani Yanick P Hagemeijer Niek Verweij Joylene E Siland Michiaki Kubo Jonathan D Smith David R Van Wagoner Joshua C Bis Siegfried Perz Bruce M Psaty Paul M Ridker Jared W Magnani Tamara B Harris Lenore J Launer M Benjamin Shoemaker Sandosh Padmanabhan Jeffrey Haessler Traci M Bartz Melanie Waldenberger Peter Lichtner Marina Arendt Jose E Krieger Mika Kähönen Lorenz Risch Alfredo J Mansur Annette Peters Blair H Smith Lars Lind Stuart A Scott Yingchang Lu Erwin B Bottinger Jussi Hernesniemi Cecilia M Lindgren Jorge A Wong Jie Huang Markku Eskola Andrew P Morris Ian Ford Alex P Reiner Graciela Delgado Lin Y Chen Yii-Der Ida Chen Roopinder K Sandhu Man Li Eric Boerwinkle Lewin Eisele Lars Lannfelt Natalia Rost Christopher D Anderson Kent D Taylor Archie Campbell Patrik K Magnusson David Porteous Lynne J Hocking Efthymia Vlachopoulou Nancy L Pedersen Kjell Nikus Marju Orho-Melander Anders Hamsten Jan Heeringa Joshua C Denny Jennifer Kriebel Dawood Darbar Christopher Newton-Cheh Christian Shaffer Peter W Macfarlane Stefanie Heilmann-Heimbach Peter Almgren Paul L Huang Nona Sotoodehnia Elsayed Z Soliman Andre G Uitterlinden Albert Hofman Oscar H Franco Uwe Völker Karl-Heinz Jöckel Moritz F Sinner Henry J Lin Xiuqing Guo Martin Dichgans Erik Ingelsson Charles Kooperberg Olle Melander Ruth J F Loos Jari Laurikka David Conen Jonathan Rosand Pim van der Harst Marja-Liisa Lokki Sekar Kathiresan Alexandre Pereira J Wouter Jukema Caroline Hayward Jerome I Rotter Winfried März Terho Lehtimäki Bruno H Stricker Mina K Chung Stephan B Felix Vilmundur Gudnason Alvaro Alonso Dan M Roden Stefan Kääb Daniel I Chasman Susan R Heckbert Emelia J Benjamin Toshihiro Tanaka Kathryn L Lunetta Steven A Lubitz Patrick T Ellinor

Nat Genet 2017 07;49(8):1286

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http://dx.doi.org/10.1038/ng0817-1286cDOI Listing
July 2017

The Pharmacogenomics of a Mutation 'Hotspot' for the Short QT Syndrome.

JACC Clin Electrophysiol 2017 07;3(7):744-746

Division of Cardiology, University of Illinois at Chicago, Chicago, IL.

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http://dx.doi.org/10.1016/j.jacep.2016.12.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617358PMC
July 2017

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

Authors:
Ingrid E Christophersen Michiel Rienstra Carolina Roselli Xiaoyan Yin Bastiaan Geelhoed John Barnard Honghuang Lin Dan E Arking Albert V Smith Christine M Albert Mark Chaffin Nathan R Tucker Molong Li Derek Klarin Nathan A Bihlmeyer Siew-Kee Low Peter E Weeke Martina Müller-Nurasyid J Gustav Smith Jennifer A Brody Maartje N Niemeijer Marcus Dörr Stella Trompet Jennifer Huffman Stefan Gustafsson Claudia Schurmann Marcus E Kleber Leo-Pekka Lyytikäinen Ilkka Seppälä Rainer Malik Andrea R V R Horimoto Marco Perez Juha Sinisalo Stefanie Aeschbacher Sébastien Thériault Jie Yao Farid Radmanesh Stefan Weiss Alexander Teumer Seung Hoan Choi Lu-Chen Weng Sebastian Clauss Rajat Deo Daniel J Rader Svati H Shah Albert Sun Jemma C Hopewell Stephanie Debette Ganesh Chauhan Qiong Yang Bradford B Worrall Guillaume Paré Yoichiro Kamatani Yanick P Hagemeijer Niek Verweij Joylene E Siland Michiaki Kubo Jonathan D Smith David R Van Wagoner Joshua C Bis Siegfried Perz Bruce M Psaty Paul M Ridker Jared W Magnani Tamara B Harris Lenore J Launer M Benjamin Shoemaker Sandosh Padmanabhan Jeffrey Haessler Traci M Bartz Melanie Waldenberger Peter Lichtner Marina Arendt Jose E Krieger Mika Kähönen Lorenz Risch Alfredo J Mansur Annette Peters Blair H Smith Lars Lind Stuart A Scott Yingchang Lu Erwin B Bottinger Jussi Hernesniemi Cecilia M Lindgren Jorge A Wong Jie Huang Markku Eskola Andrew P Morris Ian Ford Alex P Reiner Graciela Delgado Lin Y Chen Yii-Der Ida Chen Roopinder K Sandhu Man Li Eric Boerwinkle Lewin Eisele Lars Lannfelt Natalia Rost Christopher D Anderson Kent D Taylor Archie Campbell Patrik K Magnusson David Porteous Lynne J Hocking Efthymia Vlachopoulou Nancy L Pedersen Kjell Nikus Marju Orho-Melander Anders Hamsten Jan Heeringa Joshua C Denny Jennifer Kriebel Dawood Darbar Christopher Newton-Cheh Christian Shaffer Peter W Macfarlane Stefanie Heilmann-Heimbach Peter Almgren Paul L Huang Nona Sotoodehnia Elsayed Z Soliman Andre G Uitterlinden Albert Hofman Oscar H Franco Uwe Völker Karl-Heinz Jöckel Moritz F Sinner Henry J Lin Xiuqing Guo Martin Dichgans Erik Ingelsson Charles Kooperberg Olle Melander Ruth J F Loos Jari Laurikka David Conen Jonathan Rosand Pim van der Harst Marja-Liisa Lokki Sekar Kathiresan Alexandre Pereira J Wouter Jukema Caroline Hayward Jerome I Rotter Winfried März Terho Lehtimäki Bruno H Stricker Mina K Chung Stephan B Felix Vilmundur Gudnason Alvaro Alonso Dan M Roden Stefan Kääb Daniel I Chasman Susan R Heckbert Emelia J Benjamin Toshihiro Tanaka Kathryn L Lunetta Steven A Lubitz Patrick T Ellinor

Nat Genet 2017 Jun 17;49(6):946-952. Epub 2017 Apr 17.

Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585859PMC
June 2017

Relation of Obstructive Sleep Apnea and a Common Variant at Chromosome 4q25 to Atrial Fibrillation.

Am J Cardiol 2017 05 10;119(9):1387-1391. Epub 2017 Feb 10.

Division of Cardiovascular Medicine, Vanderbilt Medical Center, Nashville, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2017.01.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392162PMC
May 2017

Genetic Risk Prediction of Atrial Fibrillation.

Circulation 2017 Apr 28;135(14):1311-1320. Epub 2016 Oct 28.

From Cardiac Arrhythmia Service (S.A.L., P.T.E.), Cardiovascular Research Center (S.A.L., L.-C.W., S.K., P.T.E.), J. Philip Kistler Stroke Research Center, Department of Neurology (N.S.R., C.D.A., J.R.), and Center for Human Genetic Research (C.D.A., S.K., J.R.), Massachusetts General Hospital, Boston; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge (S.A.L., C.D.A., L.-C.W., S.K., C.R., J.R., P.T.E.); Boston University and National Heart, Lung, and Blood Institute's Framingham Heart Study, MA (X.Y., M.G.L., K.L.L., E.J.B.); Department of Pediatrics (H.J.L., X.G., K.D.T., J.I.R.) and Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute (H.J.L., X.G., K.D.T., J.Y., J.I.R.), Harbor-UCLA Medical Center, Torrance, CA; Vanderbilt University, Nashville, TN (M.K., P.L.T., D.D.); Department of Cardiology, Clinical Sciences, Lund University, Sweden (J.G.S.); Skåne University Hospital, Lund, Sweden (J.G.S.); Departments of Cardiology (S.T., J.W.J.) and Gerontology and Geriatrics (S.T.), Leiden University Medical Center, the Netherlands; University of Groningen, University Medical Center Groningen, the Netherlands (M.R., B.G., N.V., J.E.S., P.v.d.H.); Department of Clinical Sciences, Lund University, Malmö, Sweden (P.A., G.E., O.M.); Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis (L.Y.C.); Robertson Center for Biostatistics (I.F.) and Institute of Cardiovascular and Medical Sciences (P.W.M., D.J.S.), University of Glasgow, UK; Department of Neurology, Rhode Island Hospital, Alpert Medical School of Brown University, Providence (K.L.F.); Department of Mathematics and Statistics, Boston University, Boston, MA (M.G.L.); Department of Biostatistics (M.G.L., K.L.L.), Department of Epidemiology (E.J.B.), Section of Cardiovascular Medicine, Department of Medicine (E.J.B.), and Preventive Medicine Section, Department of Medicine (E.J.B.), Boston University School of Public Health, MA; Cardiovascular Health Research Unit, Departments of Medicine (B.M.P., N.S., S.R.H.), Epidemiology (B.M.P., N.S., S.R.H.), and Health Services (B.M.P.), University of Washington, Seattle; Kaiser Permanente Health Research Institute, Kaiser Permanente, Seattle, WA (B.M.P., S.R.H.); Epidemiological Cardiology Research Center (EPICARE), Wake Forest School of Medicine, Winston-Salem, NC (E.Z.S.); Department of Medicine and Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN (D.R.); University of Illinois, Chicago (D.D.); Interuniversity Cardiology Institute of the Netherlands, Utrecht (J.W.J.); Department of Internal Medicine, Skåne University Hospital, Malmö, Sweden (O.M.); and Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (A.A.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5380586PMC
April 2017

Genetic Risk Scores for Atrial Fibrillation: Do They Improve Risk Estimation?

Can J Cardiol 2017 04 14;33(4):422-424. Epub 2016 Dec 14.

Division of Cardiology, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2016.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5367929PMC
April 2017

Investigating the Genetic Architecture of the PR Interval Using Clinical Phenotypes.

Circ Cardiovasc Genet 2017 Apr;10(2)

From the Department of Medicine (J.D.M., M.B.S., Q.S.W., C.M.S., J.C.D., D.M.R.), Vanderbilt Epidemiology Center (T.L.E.), Department of Biomedical Informatics (L.B., J.C.D., D.M.R.), Department of Pharmacology (D.M.R.), Vanderbilt University, Nashville, TN; Division of Cardiology, University of Illinois at Chicago (D.D.); Essentia Institute of Rural Health, Duluth, MN (C.A.M.); Center for Biomedical Research Informatics, NorthShore University Health System, Evanston, IL (W.T.); School of Medicine (C.G.C.), School of Public Health (C.G.C.), and School of Nursing (C.G.C.), Johns Hopkins University, Baltimore, MD; Division of Medical Genetics, Department of Medicine (G.P.J.), Department of Genome Sciences (G.P.J.), Department of Biomedical Informatics (D.R.C.), Department of Medical Education (D.R.C.), University of Washington; Group Health Research Institute, Seattle, WA (E.B.L.); Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN (I.J.K.); Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (J.A.P.); Biomedical Informatics Research Center (P.L.P.), Center for Human Genetics (M.H.B., J.G.L.), Marshfield Clinic Research Foundation, WI; and Department of Epidemiology and Biostatistics, University of California, San Francisco (J.S.W.).

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001482DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5434456PMC
April 2017

Genotype influence in responses to therapy for atrial fibrillation.

Expert Rev Cardiovasc Ther 2016 Oct 15;14(10):1119-31. Epub 2016 Jul 15.

a Division of Cardiology, Department of Medicine , University of Illinois at Chicago , Chicago , IL , USA.

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http://dx.doi.org/10.1080/14779072.2016.1210510DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5260484PMC
October 2016

The "Double" Paradox of Atrial Fibrillation in Black Individuals.

JAMA Cardiol 2016 07;1(4):377-9

Division of Cardiology, University of Illinois at Chicago, Chicago, Illinois.

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http://dx.doi.org/10.1001/jamacardio.2016.1259DOI Listing
July 2016

Proarrhythmic and Torsadogenic Effects of Potassium Channel Blockers in Patients.

Card Electrophysiol Clin 2016 06 22;8(2):481-93. Epub 2016 Mar 22.

Division of Cardiology, Department of Medicine, University of Illinois at Chicago, 840 South Wood Street, Suite 920 (MC715), Chicago, IL 60612, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccep.2016.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893766PMC
June 2016

The Role of Pharmacogenetics in Atrial Fibrillation Therapeutics: Is Personalized Therapy in Sight?

Authors:
Dawood Darbar

J Cardiovasc Pharmacol 2016 Jan;67(1):9-18

Divisions of Cardiovascular Medicine and Clinical Pharmacology, Vanderbilt University, Nashville, TN.

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http://dx.doi.org/10.1097/FJC.0000000000000280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4639470PMC
January 2016

Gene-guided therapy for catheter-ablation of atrial fibrillation: are we there yet?

J Interv Card Electrophysiol 2016 Jan 11;45(1):3-5. Epub 2015 Dec 11.

Department of Medicine, Division of Cardiology, University of Illinois at Chicago, 840 S. Wood Street, 920S (MC 715), Chicago, IL, 60612, USA.

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http://dx.doi.org/10.1007/s10840-015-0086-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4744124PMC
January 2016

Atrial Fibrillation Is an Independent Predictor of Mortality in Critically Ill Patients.

Crit Care Med 2015 Oct;43(10):2104-11

1Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 2Division of Pulmonary and Critical Care Medicine, Chiayi Christian Hospital, Chiayi, Taiwan. 3Section of Pulmonary and Critical Care Medicine, Louisiana State University School of Medicine New Orleans, LA. 4Department of Surgery, Vanderbilt University School of Medicine, Nashville, TN. 5Division of Cardiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN. 6Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN.

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http://ac.els-cdn.com/S0914508714001737/1-s2.0-S091450871400
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http://dx.doi.org/10.1097/CCM.0000000000001166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4725582PMC
October 2015

Common genetic variants and response to atrial fibrillation ablation.

Circ Arrhythm Electrophysiol 2015 Apr 14;8(2):296-302. Epub 2015 Feb 14.

From the Department of Medicine, Vanderbilt University, Nashville, TN (M.B.S., J.M., T.E., Z.Y., J.D., S.K.G., P.S., A.K., S.P.W., D.M.R., C.R.E., D.D.); Department of Electrophysiology, Heart Center Leipzig, Leipzig, Germany (A.B., L.U., A.A., P.S., G.H., D.H.); Cardiac Arrhythmia Service and Cardiovascular Research Center, Massachusetts General Hospital, Boston (S.A.L., H.S., P.T.E.); and Department of Medicine, University Hospital Munich, Munich, Germany (M.F.S.).

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http://dx.doi.org/10.1161/CIRCEP.114.001909DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4731871PMC
April 2015

The AFFORD clinical decision aid to identify emergency department patients with atrial fibrillation at low risk for 30-day adverse events.

Am J Cardiol 2015 Mar 6;115(6):763-70. Epub 2015 Jan 6.

Division of Cardiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Division of Clinical Pharmacology, Department of Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee.

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http://dx.doi.org/10.1016/j.amjcard.2014.12.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346475PMC
March 2015

Ictal asystole and ictal syncope: insights into clinical management.

Circ Arrhythm Electrophysiol 2015 Feb 12;8(1):159-64. Epub 2014 Nov 12.

From the Autonomic Dysfunction Center (M.B., W.D.D., S.R.R.), Departments of Medicine (M.B., D.D., S.R.R.), Pharmacology (D.D., S.R.R.), Neurology (A.A., B.A.-K.), and Biostatistics (D.P., W.D.D.), Vanderbilt University School of Medicine, Nashville, TN; Department of Cardiac Sciences, Libin Cardiovascular Institute, University of Calgary, Calgary, Alberta, Canada (S.R.R.).

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http://dx.doi.org/10.1161/CIRCEP.114.001667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334668PMC
February 2015

Examining rare and low-frequency genetic variants previously associated with lone or familial forms of atrial fibrillation in an electronic medical record system: a cautionary note.

Circ Cardiovasc Genet 2015 Feb 19;8(1):58-63. Epub 2014 Nov 19.

From the Department of Internal Medicine (P.W., J.C.D., C.S., C.I., D.D., D.M.R.) and Department of Biomedical Informatics (J.C.D., L.B.), Vanderbilt University Medical Center, Nashville, TN; Department of Cardiology, Copenhagen University Hospital, Gentofte, Denmark (P.W.); and Institute for Clinical and Translational Research, Vanderbilt University School of Medicine, Nashville, TN (E.B.).

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http://dx.doi.org/10.1161/CIRCGENETICS.114.000718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334677PMC
February 2015

Effect of omega-three polyunsaturated fatty acids on inflammation, oxidative stress, and recurrence of atrial fibrillation.

Am J Cardiol 2015 Jan 29;115(2):196-201. Epub 2014 Oct 29.

Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2014.10.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276435PMC
January 2015

Atrial Fibrillation and Variants.

Card Electrophysiol Clin 2014 Dec;6(4):741-748

Division of Cardiovascular Medicine, Vanderbilt University, Nashville, TN.

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http://dx.doi.org/10.1016/j.ccep.2014.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254730PMC
December 2014

SCN10A/Nav1.8 modulation of peak and late sodium currents in patients with early onset atrial fibrillation.

Cardiovasc Res 2014 Nov 22;104(2):355-63. Epub 2014 Jul 22.

Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, 2215B Garland Avenue, Room 1285A MRB IV, Nashville, TN 37323-6602, USA Division of Clinical Pharmacology, Vanderbilt University School of Medicine, 2215B Garland Avenue, Room 1285A MRB IV, Nashville, TN 37323-6602, USA

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4271018PMC
November 2014

Whole-exome sequencing in familial atrial fibrillation.

Eur Heart J 2014 Sep 11;35(36):2477-83. Epub 2014 Apr 11.

Division of Clinical Pharmacology, Vanderbilt University, Nashville, TN, USA Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, 2215B Garland Avenue, Room 1285A MRB IV, Nashville 37323-6602, TN, USA.

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http://dx.doi.org/10.1093/eurheartj/ehu156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169871PMC
September 2014

2014 AATS guidelines for the prevention and management of perioperative atrial fibrillation and flutter for thoracic surgical procedures. Executive summary.

J Thorac Cardiovasc Surg 2014 Sep 28;148(3):772-91. Epub 2014 Jun 28.

Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Mass.

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September 2014

Improved understanding of the pathophysiology of atrial fibrillation through the lens of discrete pathological pathways.

Glob Cardiol Sci Pract 2014 29;2014(1):24-36. Epub 2014 Jan 29.

Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.5339/gcsp.2014.5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104374PMC
July 2014

Common SCN10A variants modulate PR interval and heart rate response during atrial fibrillation.

Europace 2014 Apr 26;16(4):485-90. Epub 2013 Sep 26.

Division of Cardiovascular Medicine, Departments of Medicine, Vanderbilt University School of Medicine, 2215B Garland Avenue, Room 1275 MRB IV, Room 1275 MRB IV, Nashville, TN 37232-6602, USA.

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http://dx.doi.org/10.1093/europace/eut278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977588PMC
April 2014

Suppression of spontaneous ca elevations prevents atrial fibrillation in calsequestrin 2-null hearts.

Circ Arrhythm Electrophysiol 2014 Apr 3;7(2):313-20. Epub 2014 Feb 3.

Division of Clinical Pharmacology, Department of Medicine, Division of Cardiology, Department of Medicine, Department of Biomedical Engineering and Physics, and Division of Cardiology, Department of Pediatrics, Vanderbilt University, Nashville, TN; and Department of Cardiovascular Diseases, University of Pisa, Pisa, Italy.

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http://dx.doi.org/10.1161/CIRCEP.113.000994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989424PMC
April 2014

Candidate gene approach to identifying rare genetic variants associated with lone atrial fibrillation.

Heart Rhythm 2014 Jan 10;11(1):46-52. Epub 2013 Oct 10.

Department of Medicine, Vanderbilt University, Nashville, Tennessee. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947369PMC
January 2014

A common variant on chromosome 4q25 is associated with prolonged PR interval in subjects with and without atrial fibrillation.

Am J Cardiol 2014 Jan 3;113(2):309-13. Epub 2013 Oct 3.

Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Division of Clinical Pharmacology, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947341PMC
January 2014

Selective targeting of gain-of-function KCNQ1 mutations predisposing to atrial fibrillation.

Circ Arrhythm Electrophysiol 2013 Oct 4;6(5):960-6. Epub 2013 Sep 4.

Department of Pharmacology and Department of Medicine, Vanderbilt University, Nashville, TN; and Department of Engineering Management, Information, and Systems, Southern Methodist University, Dallas, TX.

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http://dx.doi.org/10.1161/CIRCEP.113.000439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892565PMC
October 2013

Common genetic polymorphism at 4q25 locus predicts atrial fibrillation recurrence after successful cardioversion.

Heart Rhythm 2013 Jun 19;10(6):849-55. Epub 2013 Feb 19.

Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37323- 6602, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3690553PMC
June 2013

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.

Authors:
Marcel den Hoed Mark Eijgelsheim Tõnu Esko Bianca J J M Brundel David S Peal David M Evans Ilja M Nolte Ayellet V Segrè Hilma Holm Robert E Handsaker Harm-Jan Westra Toby Johnson Aaron Isaacs Jian Yang Alicia Lundby Jing Hua Zhao Young Jin Kim Min Jin Go Peter Almgren Murielle Bochud Gabrielle Boucher Marilyn C Cornelis Daniel Gudbjartsson David Hadley Pim van der Harst Caroline Hayward Martin den Heijer Wilmar Igl Anne U Jackson Zoltán Kutalik Jian'an Luan John P Kemp Kati Kristiansson Claes Ladenvall Mattias Lorentzon May E Montasser Omer T Njajou Paul F O'Reilly Sandosh Padmanabhan Beate St Pourcain Tuomo Rankinen Perttu Salo Toshiko Tanaka Nicholas J Timpson Veronique Vitart Lindsay Waite William Wheeler Weihua Zhang Harmen H M Draisma Mary F Feitosa Kathleen F Kerr Penelope A Lind Evelin Mihailov N Charlotte Onland-Moret Ci Song Michael N Weedon Weijia Xie Loic Yengo Devin Absher Christine M Albert Alvaro Alonso Dan E Arking Paul I W de Bakker Beverley Balkau Cristina Barlassina Paola Benaglio Joshua C Bis Nabila Bouatia-Naji Søren Brage Stephen J Chanock Peter S Chines Mina Chung Dawood Darbar Christian Dina Marcus Dörr Paul Elliott Stephan B Felix Krista Fischer Christian Fuchsberger Eco J C de Geus Philippe Goyette Vilmundur Gudnason Tamara B Harris Anna-Liisa Hartikainen Aki S Havulinna Susan R Heckbert Andrew A Hicks Albert Hofman Suzanne Holewijn Femke Hoogstra-Berends Jouke-Jan Hottenga Majken K Jensen Asa Johansson Juhani Junttila Stefan Kääb Bart Kanon Shamika Ketkar Kay-Tee Khaw Joshua W Knowles Angrad S Kooner Jan A Kors Meena Kumari Lili Milani Päivi Laiho Edward G Lakatta Claudia Langenberg Maarten Leusink Yongmei Liu Robert N Luben Kathryn L Lunetta Stacey N Lynch Marcello R P Markus Pedro Marques-Vidal Irene Mateo Leach Wendy L McArdle Steven A McCarroll Sarah E Medland Kathryn A Miller Grant W Montgomery Alanna C Morrison Martina Müller-Nurasyid Pau Navarro Mari Nelis Jeffrey R O'Connell Christopher J O'Donnell Ken K Ong Anne B Newman Annette Peters Ozren Polasek Anneli Pouta Peter P Pramstaller Bruce M Psaty Dabeeru C Rao Susan M Ring Elizabeth J Rossin Diana Rudan Serena Sanna Robert A Scott Jaban S Sehmi Stephen Sharp Jordan T Shin Andrew B Singleton Albert V Smith Nicole Soranzo Tim D Spector Chip Stewart Heather M Stringham Kirill V Tarasov André G Uitterlinden Liesbeth Vandenput Shih-Jen Hwang John B Whitfield Cisca Wijmenga Sarah H Wild Gonneke Willemsen James F Wilson Jacqueline C M Witteman Andrew Wong Quenna Wong Yalda Jamshidi Paavo Zitting Jolanda M A Boer Dorret I Boomsma Ingrid B Borecki Cornelia M van Duijn Ulf Ekelund Nita G Forouhi Philippe Froguel Aroon Hingorani Erik Ingelsson Mika Kivimaki Richard A Kronmal Diana Kuh Lars Lind Nicholas G Martin Ben A Oostra Nancy L Pedersen Thomas Quertermous Jerome I Rotter Yvonne T van der Schouw W M Monique Verschuren Mark Walker Demetrius Albanes David O Arnar Themistocles L Assimes Stefania Bandinelli Michael Boehnke Rudolf A de Boer Claude Bouchard W L Mark Caulfield John C Chambers Gary Curhan Daniele Cusi Johan Eriksson Luigi Ferrucci Wiek H van Gilst Nicola Glorioso Jacqueline de Graaf Leif Groop Ulf Gyllensten Wen-Chi Hsueh Frank B Hu Heikki V Huikuri David J Hunter Carlos Iribarren Bo Isomaa Marjo-Riitta Jarvelin Antti Jula Mika Kähönen Lambertus A Kiemeney Melanie M van der Klauw Jaspal S Kooner Peter Kraft Licia Iacoviello Terho Lehtimäki Marja-Liisa L Lokki Braxton D Mitchell Gerjan Navis Markku S Nieminen Claes Ohlsson Neil R Poulter Lu Qi Olli T Raitakari Eric B Rimm John D Rioux Federica Rizzi Igor Rudan Veikko Salomaa Peter S Sever Denis C Shields Alan R Shuldiner Juha Sinisalo Alice V Stanton Ronald P Stolk David P Strachan Jean-Claude Tardif Unnur Thorsteinsdottir Jaako Tuomilehto Dirk J van Veldhuisen Jarmo Virtamo Jorma Viikari Peter Vollenweider Gérard Waeber Elisabeth Widen Yoon Shin Cho Jesper V Olsen Peter M Visscher Cristen Willer Lude Franke Jeanette Erdmann John R Thompson Arne Pfeufer Nona Sotoodehnia Christopher Newton-Cheh Patrick T Ellinor Bruno H Ch Stricker Andres Metspalu Markus Perola Jacques S Beckmann George Davey Smith Kari Stefansson Nicholas J Wareham Patricia B Munroe Ody C M Sibon David J Milan Harold Snieder Nilesh J Samani Ruth J F Loos

Nat Genet 2013 Jun 14;45(6):621-31. Epub 2013 Apr 14.

Medical Research Council MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.

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June 2013

Genetic mechanisms of atrial fibrillation: impact on response to treatment.

Nat Rev Cardiol 2013 Jun 16;10(6):317-29. Epub 2013 Apr 16.

Departments of Medicine and Pharmacology, Vanderbilt University School of Medicine, 2215B Garland Avenue, Nashville, TN 37323-6602, USA.

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http://dx.doi.org/10.1038/nrcardio.2013.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664212PMC
June 2013

Evaluating the HATCH score for predicting progression to sustained atrial fibrillation in ED patients with new atrial fibrillation.

Am J Emerg Med 2013 May 9;31(5):792-7. Epub 2013 Mar 9.

Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN 37232-4700, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655117PMC
May 2013

Race-specific impact of atrial fibrillation risk factors in blacks and whites in the southern community cohort study.

Am J Cardiol 2012 Dec 23;110(11):1637-42. Epub 2012 Aug 23.

Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1016/j.amjcard.2012.07.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496834PMC
December 2012

Risk factors for bradycardia requiring pacemaker implantation in patients with atrial fibrillation.

Am J Cardiol 2012 Nov 26;110(9):1315-21. Epub 2012 Jul 26.

Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1016/j.amjcard.2012.06.037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470776PMC
November 2012

A KCNJ8 mutation associated with early repolarization and atrial fibrillation.

Europace 2012 Oct 4;14(10):1428-32. Epub 2012 May 4.

Departments of Medicine and Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1093/europace/eus150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458578PMC
October 2012

Voltage-gated sodium channels: biophysics, pharmacology, and related channelopathies.

Front Pharmacol 2012 11;3:124. Epub 2012 Jul 11.

Division of Cardiovascular Medicine, Department of Medicine, Vanderbilt University Nashville, TN, USA.

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http://dx.doi.org/10.3389/fphar.2012.00124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3394224PMC
October 2012

Chromosome 4q25 variants are genetic modifiers of rare ion channel mutations associated with familial atrial fibrillation.

J Am Coll Cardiol 2012 Sep 18;60(13):1173-81. Epub 2012 Jul 18.

Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1016/j.jacc.2012.04.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3448817PMC
September 2012

Symptomatic response to antiarrhythmic drug therapy is modulated by a common single nucleotide polymorphism in atrial fibrillation.

J Am Coll Cardiol 2012 Aug 20;60(6):539-45. Epub 2012 Jun 20.

Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37323-6602, USA.

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http://dx.doi.org/10.1016/j.jacc.2012.01.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3411889PMC
August 2012

Meta-analysis identifies six new susceptibility loci for atrial fibrillation.

Nat Genet 2012 Apr 29;44(6):670-5. Epub 2012 Apr 29.

Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.2261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366038PMC
April 2012

The "missing" link in atrial fibrillation heritability.

J Electrocardiol 2011 Nov-Dec;44(6):641-4. Epub 2011 Sep 15.

Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37323-6602, USA.

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http://dx.doi.org/10.1016/j.jelectrocard.2011.07.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200486PMC
February 2012

Assessment of the Framingham risk factors among ED patients with newly diagnosed atrial fibrillation.

Am J Emerg Med 2012 Jan 3;30(1):151-7. Epub 2011 Jan 3.

Department of Emergency Medicine Vanderbilt University Medical Center Nashville, TN 37232-4700, USA.

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http://dx.doi.org/10.1016/j.ajem.2010.11.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3084346PMC
January 2012

Atrial fibrillation and flutter outcomes and risk determination (AFFORD): design and rationale.

J Cardiol 2011 Sep 4;58(2):124-30. Epub 2011 Aug 4.

Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1016/j.jjcc.2011.06.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169197PMC
September 2011

Novel ECG markers for ventricular repolarization: Is the QT interval obsolete?

Heart Rhythm 2011 Jul 22;8(7):1044-5. Epub 2011 Feb 22.

Divisions of Cardiovascular Medicine and Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3107864PMC
July 2011

Differential impact of race and risk factors on incidence of atrial fibrillation.

Am Heart J 2011 Jul;162(1):31-7

University of Tennessee Erlanger Cardiology, UT College of Medicine, Chattanooga, TN, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3137277PMC
July 2011

Drug-induced long QT syndrome.

Pharmacol Rev 2010 Dec;62(4):760-81

Oates Institute for Experimental Therapeutics, Vanderbilt University School of Medicine, Nashville, TN 37232-0575, USA.

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http://dx.doi.org/10.1124/pr.110.003723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2993258PMC
December 2010

Sotalol-induced torsades de pointes precipitated during treatment with oseltamivir for H1N1 influenza.

Heart Rhythm 2010 Oct 23;7(10):1454-7. Epub 2010 Jul 23.

Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37323, USA.

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http://dx.doi.org/10.1016/j.hrthm.2010.07.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946414PMC
October 2010

Novel KCNA5 mutation implicates tyrosine kinase signaling in human atrial fibrillation.

Heart Rhythm 2010 Sep 1;7(9):1246-52. Epub 2010 Jun 1.

Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee 37323-6602, USA.

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http://dx.doi.org/10.1016/j.hrthm.2010.05.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2932792PMC
September 2010

Lone AF - Etiologic Factors and Genetic Insights into Pathophysiolgy.

J Atr Fibrillation 2010 Jun-Jul;3(1):236. Epub 2010 Jun 1.

Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2911796PMC
June 2010

Atrial Fibrillation Susceptibility Alleles on Chromosome 4q25 Modulate Response to Catheter Ablation.

Authors:
Dawood Darbar

J Atr Fibrillation 2010 Jun-Jul;3(1):272. Epub 2010 Jun 1.

Divisions of Cardiovascular Medicine and Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, TN.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3115649PMC
June 2010

Role of inflammation and oxidative stress in atrial fibrillation.

Heart Rhythm 2010 Apr 24;7(4):438-44. Epub 2009 Dec 24.

Division of Clinical Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2843774PMC
April 2010

Common variants in KCNN3 are associated with lone atrial fibrillation.

Nat Genet 2010 Mar 21;42(3):240-4. Epub 2010 Feb 21.

[1] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [4] These authors contributed equally to this work.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387PMC
March 2010

Augmented potassium current is a shared phenotype for two genetic defects associated with familial atrial fibrillation.

J Mol Cell Cardiol 2010 Jan 30;48(1):181-90. Epub 2009 Jul 30.

Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, 1285A MRB IV, 2311 Pierce Avenue, Nashville, TN 37232-6602, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813326PMC
January 2010

Arrhythmia pharmacogenomics: methodological considerations.

Curr Pharm Des 2009 ;15(32):3734-41

Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-0575, USA.

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http://dx.doi.org/10.2174/138161209789649529DOI Listing
January 2010

Mutations in sodium channel β1- and β2-subunits associated with atrial fibrillation.

Circ Arrhythm Electrophysiol 2009 Jun 6;2(3):268-75. Epub 2009 Mar 6.

Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232-0575, USA.

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http://dx.doi.org/10.1161/CIRCEP.108.779181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2727725PMC
June 2009