Dawn L Demeo

Dawn L Demeo

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Dawn L Demeo

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COPDGene 2019: Redefining the Diagnosis of Chronic Obstructive Pulmonary Disease.

Authors:
Katherine E Lowe Elizabeth A Regan Antonio Anzueto Erin Austin John H M Austin Terri H Beaty Panayiotis V Benos Christopher J Benway Surya P Bhatt Eugene R Bleecker Sandeep Bodduluri Jessica Bon Aladin M Boriek Adel Re Boueiz Russell P Bowler Matthew Budoff Richard Casaburi Peter J Castaldi Jean-Paul Charbonnier Michael H Cho Alejandro Comellas Douglas Conrad Corinne Costa Davis Gerard J Criner Douglas Curran-Everett Jeffrey L Curtis Dawn L DeMeo Alejandro A Diaz Mark T Dransfield Jennifer G Dy Ashraf Fawzy Margaret Fleming Eric L Flenaugh Marilyn G Foreman Spyridon Fortis Hirut Gebrekristos Sarah Grant Philippe A Grenier Tian Gu Abhya Gupta MeiLan K Han Nicola A Hanania Nadia N Hansel Lystra P Hayden Craig P Hersh Brian D Hobbs Eric A Hoffman James C Hogg John E Hokanson Karin F Hoth Albert Hsiao Stephen Humphries Kathleen Jacobs Francine L Jacobson Ella A Kazerooni Victor Kim Woo Jin Kim Gregory L Kinney Harald Koegler Sharon M Lutz David A Lynch Neil R MacIntye Barry J Make Nathaniel Marchetti Fernando J Martinez Diego J Maselli Anne M Mathews Meredith C McCormack Merry-Lynn N McDonald Charlene E McEvoy Matthew Moll Sarah S Molye Susan Murray Hrudaya Nath John D Newell Mariaelena Occhipinti Matteo Paoletti Trisha Parekh Massimo Pistolesi Katherine A Pratte Nirupama Putcha Margaret Ragland Joseph M Reinhardt Stephen I Rennard Richard A Rosiello James C Ross Harry B Rossiter Ingo Ruczinski Raul San Jose Estepar Frank C Sciurba Jessica C Sieren Harjinder Singh Xavier Soler Robert M Steiner Matthew J Strand William W Stringer Ruth Tal-Singer Byron Thomashow Gonzalo Vegas Sánchez-Ferrero John W Walsh Emily S Wan George R Washko J Michael Wells Chris H Wendt Gloria Westney Ava Wilson Robert A Wise Andrew Yen Kendra Young Jeong Yun Edwin K Silverman James D Crapo

Chronic Obstr Pulm Dis 2019 Nov;6(5):384-399

National Jewish Health, Denver, Colorado.

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http://dx.doi.org/10.15326/jcopdf.6.5.2019.0149DOI Listing
November 2019

DNA methylation is associated with inhaled corticosteroid response in persistent childhood asthmatics.

Clin Exp Allergy 2019 Sep 15;49(9):1225-1234. Epub 2019 Aug 15.

Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1111/cea.13447DOI Listing
September 2019

Maternal corticotropin-releasing hormone is associated with LEP DNA methylation at birth and in childhood: an epigenome-wide study in Project Viva.

Int J Obes (Lond) 2019 06 21;43(6):1244-1255. Epub 2018 Nov 21.

Division of Chronic Disease Research Across the Lifecourse, Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41366-018-0249-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529291PMC
June 2019

Epigenetic age acceleration is associated with allergy and asthma in children in Project Viva.

J Allergy Clin Immunol 2019 Jun 6;143(6):2263-2270.e14. Epub 2019 Feb 6.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.

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http://dx.doi.org/10.1016/j.jaci.2019.01.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556426PMC
June 2019

Author Correction: New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Authors:
Nick Shrine Anna L Guyatt A Mesut Erzurumluoglu Victoria E Jackson Brian D Hobbs Carl A Melbourne Chiara Batini Katherine A Fawcett Kijoung Song Phuwanat Sakornsakolpat Xingnan Li Ruth Boxall Nicola F Reeve Ma'en Obeidat Jing Hua Zhao Matthias Wielscher Stefan Weiss Katherine A Kentistou James P Cook Benjamin B Sun Jian Zhou Jennie Hui Stefan Karrasch Medea Imboden Sarah E Harris Jonathan Marten Stefan Enroth Shona M Kerr Ida Surakka Veronique Vitart Terho Lehtimäki Richard J Allen Per S Bakke Terri H Beaty Eugene R Bleecker Yohan Bossé Corry-Anke Brandsma Zhengming Chen James D Crapo John Danesh Dawn L DeMeo Frank Dudbridge Ralf Ewert Christian Gieger Amund Gulsvik Anna L Hansell Ke Hao Joshua D Hoffman John E Hokanson Georg Homuth Peter K Joshi Philippe Joubert Claudia Langenberg Xuan Li Liming Li Kuang Lin Lars Lind Nicholas Locantore Jian'an Luan Anubha Mahajan Joseph C Maranville Alison Murray David C Nickle Richard Packer Margaret M Parker Megan L Paynton David J Porteous Dmitry Prokopenko Dandi Qiao Rajesh Rawal Heiko Runz Ian Sayers Don D Sin Blair H Smith María Soler Artigas David Sparrow Ruth Tal-Singer Paul R H J Timmers Maarten Van den Berge John C Whittaker Prescott G Woodruff Laura M Yerges-Armstrong Olga G Troyanskaya Olli T Raitakari Mika Kähönen Ozren Polašek Ulf Gyllensten Igor Rudan Ian J Deary Nicole M Probst-Hensch Holger Schulz Alan L James James F Wilson Beate Stubbe Eleftheria Zeggini Marjo-Riitta Jarvelin Nick Wareham Edwin K Silverman Caroline Hayward Andrew P Morris Adam S Butterworth Robert A Scott Robin G Walters Deborah A Meyers Michael H Cho David P Strachan Ian P Hall Martin D Tobin Louise V Wain

Nat Genet 2019 Jun;51(6):1067

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/s41588-019-0438-3DOI Listing
June 2019

Epigenome-wide association study of total serum immunoglobulin E in children: a life course approach.

Clin Epigenetics 2018 17;10:55. Epub 2018 Apr 17.

Channing Division of Network Medicine and the Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, 181 Longwood Avenue, 4th Floor, Boston, MA 02115 USA.

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http://dx.doi.org/10.1186/s13148-018-0488-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905182PMC
May 2019

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Authors:
Leanne K Küpers Claire Monnereau Gemma C Sharp Paul Yousefi Lucas A Salas Akram Ghantous Christian M Page Sarah E Reese Allen J Wilcox Darina Czamara Anne P Starling Alexei Novoloaca Samantha Lent Ritu Roy Cathrine Hoyo Carrie V Breton Catherine Allard Allan C Just Kelly M Bakulski John W Holloway Todd M Everson Cheng-Jian Xu Rae-Chi Huang Diana A van der Plaat Matthias Wielscher Simon Kebede Merid Vilhelmina Ullemar Faisal I Rezwan Jari Lahti Jenny van Dongen Sabine A S Langie Tom G Richardson Maria C Magnus Ellen A Nohr Zongli Xu Liesbeth Duijts Shanshan Zhao Weiming Zhang Michelle Plusquin Dawn L DeMeo Olivia Solomon Joosje H Heimovaara Dereje D Jima Lu Gao Mariona Bustamante Patrice Perron Robert O Wright Irva Hertz-Picciotto Hongmei Zhang Margaret R Karagas Ulrike Gehring Carmen J Marsit Lawrence J Beilin Judith M Vonk Marjo-Riitta Jarvelin Anna Bergström Anne K Örtqvist Susan Ewart Pia M Villa Sophie E Moore Gonneke Willemsen Arnout R L Standaert Siri E Håberg Thorkild I A Sørensen Jack A Taylor Katri Räikkönen Ivana V Yang Katerina Kechris Tim S Nawrot Matt J Silver Yun Yun Gong Lorenzo Richiardi Manolis Kogevinas Augusto A Litonjua Brenda Eskenazi Karen Huen Hamdi Mbarek Rachel L Maguire Terence Dwyer Martine Vrijheid Luigi Bouchard Andrea A Baccarelli Lisa A Croen Wilfried Karmaus Denise Anderson Maaike de Vries Sylvain Sebert Juha Kere Robert Karlsson Syed Hasan Arshad Esa Hämäläinen Michael N Routledge Dorret I Boomsma Andrew P Feinberg Craig J Newschaffer Eva Govarts Matthieu Moisse M Daniele Fallin Erik Melén Andrew M Prentice Eero Kajantie Catarina Almqvist Emily Oken Dana Dabelea H Marike Boezen Phillip E Melton Rosalind J Wright Gerard H Koppelman Letizia Trevisi Marie-France Hivert Jordi Sunyer Monica C Munthe-Kaas Susan K Murphy Eva Corpeleijn Joseph Wiemels Nina Holland Zdenko Herceg Elisabeth B Binder George Davey Smith Vincent W V Jaddoe Rolv T Lie Wenche Nystad Stephanie J London Debbie A Lawlor Caroline L Relton Harold Snieder Janine F Felix

Nat Commun 2019 04 23;10(1):1893. Epub 2019 Apr 23.

The Generation R Study Group, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/s41467-019-09671-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478731PMC
April 2019

Women manifest more severe COPD symptoms across the life course.

Int J Chron Obstruct Pulmon Dis 2018;13:3021-3029. Epub 2018 Oct 1.

Division of Pulmonary, Critical Care, and Sleep Medicine, National Jewish Health, Denver, CO, USA.

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https://www.dovepress.com/women-manifest-more-severe-copd-sy
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http://dx.doi.org/10.2147/COPD.S160270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171761PMC
March 2019

New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.

Authors:
Nick Shrine Anna L Guyatt A Mesut Erzurumluoglu Victoria E Jackson Brian D Hobbs Carl A Melbourne Chiara Batini Katherine A Fawcett Kijoung Song Phuwanat Sakornsakolpat Xingnan Li Ruth Boxall Nicola F Reeve Ma'en Obeidat Jing Hua Zhao Matthias Wielscher Stefan Weiss Katherine A Kentistou James P Cook Benjamin B Sun Jian Zhou Jennie Hui Stefan Karrasch Medea Imboden Sarah E Harris Jonathan Marten Stefan Enroth Shona M Kerr Ida Surakka Veronique Vitart Terho Lehtimäki Richard J Allen Per S Bakke Terri H Beaty Eugene R Bleecker Yohan Bossé Corry-Anke Brandsma Zhengming Chen James D Crapo John Danesh Dawn L DeMeo Frank Dudbridge Ralf Ewert Christian Gieger Amund Gulsvik Anna L Hansell Ke Hao Joshua D Hoffman John E Hokanson Georg Homuth Peter K Joshi Philippe Joubert Claudia Langenberg Xuan Li Liming Li Kuang Lin Lars Lind Nicholas Locantore Jian'an Luan Anubha Mahajan Joseph C Maranville Alison Murray David C Nickle Richard Packer Margaret M Parker Megan L Paynton David J Porteous Dmitry Prokopenko Dandi Qiao Rajesh Rawal Heiko Runz Ian Sayers Don D Sin Blair H Smith María Soler Artigas David Sparrow Ruth Tal-Singer Paul R H J Timmers Maarten Van den Berge John C Whittaker Prescott G Woodruff Laura M Yerges-Armstrong Olga G Troyanskaya Olli T Raitakari Mika Kähönen Ozren Polašek Ulf Gyllensten Igor Rudan Ian J Deary Nicole M Probst-Hensch Holger Schulz Alan L James James F Wilson Beate Stubbe Eleftheria Zeggini Marjo-Riitta Jarvelin Nick Wareham Edwin K Silverman Caroline Hayward Andrew P Morris Adam S Butterworth Robert A Scott Robin G Walters Deborah A Meyers Michael H Cho David P Strachan Ian P Hall Martin D Tobin Louise V Wain

Nat Genet 2019 03 25;51(3):481-493. Epub 2019 Feb 25.

Department of Health Sciences, University of Leicester, Leicester, UK.

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http://dx.doi.org/10.1038/s41588-018-0321-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397078PMC
March 2019

Deep Learning Methods for Predicting Disease Status Using Genomic Data.

J Biom Biostat 2018 11;9(5). Epub 2018 Dec 11.

Channing Division of Network Medicine, Brigham and Women's Hospital/Harvard Medical School, 181 Longwood Avenue, Boston MA 02115, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6530791PMC
December 2018

The Recursive Trek of Epigenetics from the Bench to the Bedside. Predictive Methylation Marks by the Dozen.

Authors:
Dawn L DeMeo

Am J Respir Crit Care Med 2018 07;198(2):145-146

1 Brigham and Women's Hospital Harvard Medical School Boston, Massachusetts.

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http://dx.doi.org/10.1164/rccm.201803-0477EDDOI Listing
July 2018

Detecting Differentially Variable MicroRNAs via Model-Based Clustering.

Int J Genomics 2018 12;2018:6591634. Epub 2018 Jul 12.

Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1155/2018/6591634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6079429PMC
July 2018

Lobar Emphysema Distribution Is Associated With 5-Year Radiological Disease Progression.

Chest 2018 01 21;153(1):65-76. Epub 2017 Sep 21.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Division of General Medicine and Primary Care, Brigham and Women's Hospital, Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2017.09.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026264PMC
January 2018

The value of blood cytokines and chemokines in assessing COPD.

Respir Res 2017 10 24;18(1):180. Epub 2017 Oct 24.

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, National Jewish Health, 1400 Jackson St., K715, Denver, CO, 80206, USA.

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http://dx.doi.org/10.1186/s12931-017-0662-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655820PMC
October 2017

Regulatory network changes between cell lines and their tissues of origin.

BMC Genomics 2017 Sep 12;18(1):723. Epub 2017 Sep 12.

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

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http://dx.doi.org/10.1186/s12864-017-4111-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596945PMC
September 2017

Translating genomics into risk prediction.

Thorax 2017 07 20;72(7):598-599. Epub 2017 Mar 20.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/thoraxjnl-2016-209934DOI Listing
July 2017

Birth weight-for-gestational age is associated with DNA methylation at birth and in childhood.

Clin Epigenetics 2016 16;8:118. Epub 2016 Nov 16.

Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, 722 West 168th Street, New York, NY 10032 USA.

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http://dx.doi.org/10.1186/s13148-016-0285-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112715PMC
March 2017

The impact of genetic variation and cigarette smoke on DNA methylation in current and former smokers from the COPDGene study.

Epigenetics 2015 ;10(11):1064-73

a Channing Division of Network Medicine; Brigham and Women's Hospital/Harvard Medical School ; Boston , MA USA.

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http://dx.doi.org/10.1080/15592294.2015.1106672DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4844199PMC
October 2016

Epigenetic Signatures of Cigarette Smoking.

Circ Cardiovasc Genet 2016 Oct 20;9(5):436-447. Epub 2016 Sep 20.

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http://dx.doi.org/10.1161/CIRCGENETICS.116.001506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5267325PMC
October 2016

A Comparative Study of Tests for Homogeneity of Variances with Application to DNA Methylation Data.

PLoS One 2015 18;10(12):e0145295. Epub 2015 Dec 18.

Department of Mathematics and Statistics, York University, 4700 Keele Street, Toronto, ON, M3J1P3, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145295PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684215PMC
June 2016

DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.

Authors:
Bonnie R Joubert Janine F Felix Paul Yousefi Kelly M Bakulski Allan C Just Carrie Breton Sarah E Reese Christina A Markunas Rebecca C Richmond Cheng-Jian Xu Leanne K Küpers Sam S Oh Cathrine Hoyo Olena Gruzieva Cilla Söderhäll Lucas A Salas Nour Baïz Hongmei Zhang Johanna Lepeule Carlos Ruiz Symen Ligthart Tianyuan Wang Jack A Taylor Liesbeth Duijts Gemma C Sharp Soesma A Jankipersadsing Roy M Nilsen Ahmad Vaez M Daniele Fallin Donglei Hu Augusto A Litonjua Bernard F Fuemmeler Karen Huen Juha Kere Inger Kull Monica Cheng Munthe-Kaas Ulrike Gehring Mariona Bustamante Marie José Saurel-Coubizolles Bilal M Quraishi Jie Ren Jörg Tost Juan R Gonzalez Marjolein J Peters Siri E Håberg Zongli Xu Joyce B van Meurs Tom R Gaunt Marjan Kerkhof Eva Corpeleijn Andrew P Feinberg Celeste Eng Andrea A Baccarelli Sara E Benjamin Neelon Asa Bradman Simon Kebede Merid Anna Bergström Zdenko Herceg Hector Hernandez-Vargas Bert Brunekreef Mariona Pinart Barbara Heude Susan Ewart Jin Yao Nathanaël Lemonnier Oscar H Franco Michael C Wu Albert Hofman Wendy McArdle Pieter Van der Vlies Fahimeh Falahi Matthew W Gillman Lisa F Barcellos Ashish Kumar Magnus Wickman Stefano Guerra Marie-Aline Charles John Holloway Charles Auffray Henning W Tiemeier George Davey Smith Dirkje Postma Marie-France Hivert Brenda Eskenazi Martine Vrijheid Hasan Arshad Josep M Antó Abbas Dehghan Wilfried Karmaus Isabella Annesi-Maesano Jordi Sunyer Akram Ghantous Göran Pershagen Nina Holland Susan K Murphy Dawn L DeMeo Esteban G Burchard Christine Ladd-Acosta Harold Snieder Wenche Nystad Gerard H Koppelman Caroline L Relton Vincent W V Jaddoe Allen Wilcox Erik Melén Stephanie J London

Am J Hum Genet 2016 Apr 31;98(4):680-96. Epub 2016 Mar 31.

National Institute of Environmental Health Sciences, NIH, U.S. Department of Health and Human Services, Research Triangle Park, NC 27709, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2016.02.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4833289PMC
April 2016

Genome-wide site-specific differential methylation in the blood of individuals with Klinefelter syndrome.

Mol Reprod Dev 2015 May 30;82(5):377-86. Epub 2015 Apr 30.

Channing Division of Network Medicine, Brigham & Women's Hospital, Boston, Massachusetts.

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http://dx.doi.org/10.1002/mrd.22483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439255PMC
May 2015

Effect of culture conditions on microRNA expression in primary adult control and COPD lung fibroblasts in vitro.

In Vitro Cell Dev Biol Anim 2015 Apr 1;51(4):390-9. Epub 2015 Jan 1.

Pulmonary, Critical Care, Sleep and Allergy Medicine, University of Nebraska Medical Center, Omaha, NE, USA,

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http://dx.doi.org/10.1007/s11626-014-9820-8DOI Listing
April 2015

Menthol cigarette smoking in the COPDGene cohort: relationship with COPD, comorbidities and CT metrics.

Respirology 2015 Jan 19;20(1):108-14. Epub 2014 Oct 19.

Department of Medicine, National Jewish Health, Denver, Colorado, USA; Department of Internal Medicine and Research Institute of Clinical Medicine-Biomedical Research Institute of Chonbuk National University Hospital, Chonbuk National University, Jeonju, South Korea.

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http://dx.doi.org/10.1111/resp.12421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415502PMC
January 2015

A novel method for detecting association between DNA methylation and diseases using spatial information.

Genet Epidemiol 2014 Dec 22;38(8):714-21. Epub 2014 Sep 22.

Harvard University, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1002/gepi.21851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236268PMC
December 2014

Sexually-dimorphic targeting of functionally-related genes in COPD.

BMC Syst Biol 2014 Nov 28;8:118. Epub 2014 Nov 28.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1186/s12918-014-0118-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269917PMC
November 2014

Phenotypic and genetic heterogeneity among subjects with mild airflow obstruction in COPDGene.

Respir Med 2014 Oct 11;108(10):1469-80. Epub 2014 Aug 11.

Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2014.07.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4253548PMC
October 2014

DNA methylation and ancestry. The smoke starts to clear.

Am J Respir Crit Care Med 2013 Nov;188(9):1049-51

1 Channing Division of Network Medicine Harvard Medical School/Brigham & Women's Hospital Boston, Massachusetts.

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http://dx.doi.org/10.1164/rccm.201309-1644EDDOI Listing
November 2013

Interstitial pneumonitis and the risk of chronic allograft rejection in lung transplant recipients.

Chest 2013 May;143(5):1430-1435

Department of Medicine; Lung Transplant Program, Division of Pulmonary and Critical Care Medicine, Boston, MA; Harvard Medical School, Boston, MA. Electronic address:

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http://dx.doi.org/10.1378/chest.12-0354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653348PMC
May 2013

Systemic steroid exposure is associated with differential methylation in chronic obstructive pulmonary disease.

Am J Respir Crit Care Med 2012 Dec 11;186(12):1248-55. Epub 2012 Oct 11.

Channing Division of Network Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1164/rccm.201207-1280OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622442PMC
December 2012

Gene-environment interaction testing in family-based association studies with phenotypically ascertained samples: a causal inference approach.

Biostatistics 2012 Jul 13;13(3):468-81. Epub 2011 Nov 13.

Department of Biostatistics, Division of Biomedical Informatics, Center for Clinical and Translational Science, University of Kentucky, Lexington, KY 40536, USA.

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http://dx.doi.org/10.1093/biostatistics/kxr035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372944PMC
July 2012

Cigarette smoking behaviors and time since quitting are associated with differential DNA methylation across the human genome.

Hum Mol Genet 2012 Jul 6;21(13):3073-82. Epub 2012 Apr 6.

Channing Laboratory and the Division of Pulmonary and Critical Care Medicine, Brigham and Women’s Hospital, 181 Longwood Avenue, Boston, MA 02115, USA.

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http://dx.doi.org/10.1093/hmg/dds135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3373248PMC
July 2012

Variable DNA methylation is associated with chronic obstructive pulmonary disease and lung function.

Am J Respir Crit Care Med 2012 Feb 8;185(4):373-81. Epub 2011 Dec 8.

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1164/rccm.201108-1382OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297093PMC
February 2012

Combining disease models to test for gene-environment interaction in nuclear families.

Biometrics 2011 Dec 14;67(4):1260-70. Epub 2011 Mar 14.

Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1111/j.1541-0420.2011.01581.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120904PMC
December 2011

Arriving now at the crossroads of technology: sex and gender differences in COPD.

Authors:
Dawn L Demeo

COPD 2011 Aug 8;8(4):253-4. Epub 2011 Aug 8.

Channing Laboratory, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.3109/15412555.2011.604249DOI Listing
August 2011

Peripheral blood gene expression profiles in COPD subjects.

J Clin Bioinforma 2011 Apr 24;1(1):12. Epub 2011 Apr 24.

Neonatology Division and Center for Pediatric Biomedical Research, University of Rochester Medical Center, 601 Elmwood Avenue, Rochester, 14642, NY.

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http://dx.doi.org/10.1186/2043-9113-1-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164605PMC
April 2011