Davide Seripa

Davide Seripa

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Davide Seripa

Publications by authors named "Davide Seripa"

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The Role of Biomarkers in Psychiatry.

Adv Exp Med Biol 2019;1118:135-162

Neurodegenerative Disease Unit, Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy.

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http://dx.doi.org/10.1007/978-3-030-05542-4_7DOI Listing
August 2019

Biopsychosocial frailty and the risk of incident dementia: The Italian longitudinal study on aging.

Alzheimers Dement 2019 Jul 2. Epub 2019 Jul 2.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; National Institute of Gastroenterology "Saverio de Bellis", Research Hospital, Castellana Grotte, Bari, Italy; Geriatric Unit, Fondazione IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2019.04.013DOI Listing
July 2019

Promising therapies for the treatment of frontotemporal dementia clinical phenotypes: from symptomatic to disease-modifying drugs.

Expert Opin Pharmacother 2019 06 19;20(9):1091-1107. Epub 2019 Apr 19.

a Neurodegenerative Disease Unit, Department of Basic Medical Sciences, Neuroscience and Sense Organs , University of Bari "Aldo Moro" , Bari , Italy.

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https://www.tandfonline.com/doi/full/10.1080/14656566.2019.1
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http://dx.doi.org/10.1080/14656566.2019.1598377DOI Listing
June 2019

The Age-Related Central Auditory Processing Disorder: Silent Impairment of the Cognitive Ear.

Front Neurosci 2019 14;13:619. Epub 2019 Jun 14.

Otolaryngology Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy.

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http://dx.doi.org/10.3389/fnins.2019.00619DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6587609PMC
June 2019

Disease-modifying therapies for tauopathies: agents in the pipeline.

Expert Rev Neurother 2019 May 25;19(5):397-408. Epub 2019 Apr 25.

g Department of Neurological Sciences , Santa Maria University Hospital , Terni , Italy.

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http://dx.doi.org/10.1080/14737175.2019.1606715DOI Listing
May 2019

Klotho at the Edge of Alzheimer's Disease and Senile Depression.

Mol Neurobiol 2019 Mar 5;56(3):1908-1920. Epub 2018 Jul 5.

Department of Medical Sciences, Division of Internal Medicine and Chronobiology Unit, IRCCS Scientific Institute and Regional General Hospital "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Italy.

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http://dx.doi.org/10.1007/s12035-018-1200-zDOI Listing
March 2019

Amyloid-β immunotherapy for alzheimer disease: Is it now a long shot?

Ann Neurol 2019 Mar 28;85(3):303-315. Epub 2019 Jan 28.

Department of Research and Development, Chiesi Pharmaceuticals, Parma, Italy.

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http://dx.doi.org/10.1002/ana.25410DOI Listing
March 2019

Executive Dysfunction Detected with the Frontal Assessment Battery in Alzheimer's Disease Versus Vascular Dementia.

J Alzheimers Dis 2018 ;62(2):699-711

Department of Medical Sciences, Geriatric Unit and Laboratory of Gerontology and Geriatrics, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.3233/JAD-170365DOI Listing
February 2019

Late-Life Depression versus Amnestic Mild Cognitive Impairment: Alzheimer's Disease Incidence in 4 Years of Follow-Up.

Dement Geriatr Cogn Disord 2018 10;46(3-4):140-153. Epub 2018 Sep 10.

Complex Unit of Geriatrics, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.

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http://dx.doi.org/10.1159/000492489DOI Listing
January 2019

Testing a Combination of Markers of Systemic Redox Status as a Possible Tool for the Diagnosis of Late Onset Alzheimer's Disease.

Dis Markers 2018 9;2018:2576026. Epub 2018 Sep 9.

Department of Biomedical and Specialist Surgical Sciences, Section of Medical Biochemistry, Molecular Biology and Genetics, University of Ferrara, Via Luigi Borsari 46, 44121 Ferrara, Italy.

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http://dx.doi.org/10.1155/2018/2576026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151249PMC
January 2019

Understanding the Amyloid Hypothesis in Alzheimer's Disease.

J Alzheimers Dis 2019 ;68(2):493-510

Research Laboratory, Complex Structure of Geriatrics, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.3233/JAD-180802DOI Listing
January 2019

Nutritional interventions and cognitive-related outcomes in patients with late-life cognitive disorders: A systematic review.

Neurosci Biobehav Rev 2018 12 3;95:480-498. Epub 2018 Nov 3.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Geriatric Unit, Fondazione IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy; Department of Clinical Research in Neurology, Center for Neurodegenerative Diseases and the Aging Brain, University of Bari "Aldo Moro", "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01497634183050
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http://dx.doi.org/10.1016/j.neubiorev.2018.10.022DOI Listing
December 2018

Plasma β-amyloid reference values in cognitively normal subjects.

J Neurol Sci 2018 08 13;391:120-126. Epub 2018 Jun 13.

Unit of Neurodegenerative Disease, Department of Clinical Research in Neurology, University of Bari "Aldo Moro" at "Pia Fondazione Card. G. Panico", Tricase, Lecce, Italy; Unit of Neurodegenerative Disease, Department of Basic Medicine Sciences, Neuroscience, and Sense Organs, University of Bari "Aldo Moro", Bari, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2018.06.006DOI Listing
August 2018

Phytochemicals in the Treatment of Alzheimer's Disease: A Systematic Review.

Curr Drug Targets 2017 ;18(13):1487-1498

Geriatric Unit & Laboratory of Gerontology and Geriatrics, Department of Medical Sciences, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.2174/1389450117666161102121553DOI Listing
June 2018

Role of CLU, PICALM, and TNK1 Genotypes in Aging With and Without Alzheimer's Disease.

Mol Neurobiol 2018 May 19;55(5):4333-4344. Epub 2017 Jun 19.

Complex Structure of Geriatrics, Research Laboratory, Department of Medical Sciences, I.R.C.C.S. Casa Sollievo della Sofferenza, Viale Cappuccini 1, 71013, San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.1007/s12035-017-0547-xDOI Listing
May 2018

Neurocognitive Disorders and Dehydration in Older Patients: Clinical Experience Supports the Hydromolecular Hypothesis of Dementia.

Nutrients 2018 May 3;10(5). Epub 2018 May 3.

Complex Structure of Geriatrics, Department of Medical Sciences, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Viale Cappuccini 1, 71013 Foggia, Italy.

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http://dx.doi.org/10.3390/nu10050562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986442PMC
May 2018

Midlife Metabolic Profile and the Risk of Late-Life Cognitive Decline.

J Alzheimers Dis 2017 ;59(1):121-130

Department of Clinical Research in Neurology, Unit of Neurodegenerative Disease, University of Bari "Aldo Moro" at "Pia Fondazione Card. G. Panico", Tricase, Lecce, Italy.

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http://dx.doi.org/10.3233/JAD-170153DOI Listing
April 2018

Bipolar Disorder and Frontotemporal Dementia: An Intriguing Association.

J Alzheimers Dis 2017 ;55(3):973-979

Department of Basic Medical Science, Neuroscience and Sense Organs, Neurodegenerative Disease Unit, University of Bari "Aldo Moro", Bari, Italy.

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http://dx.doi.org/10.3233/JAD-160860DOI Listing
February 2018

An Old Challenge with New Promises: A Systematic Review on Comprehensive Geriatric Assessment in Long-Term Care Facilities.

Rejuvenation Res 2018 Feb 28;21(1):3-14. Epub 2017 Jul 28.

1 Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro , Bari, Italy .

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http://dx.doi.org/10.1089/rej.2017.1964DOI Listing
February 2018

Erythrocyte Associated Amyloid-β as Potential Biomarker to Diagnose Dementia.

Curr Alzheimer Res 2018 02;15(4):381-385

Complex Unit of Geriatrics, Department of Medical Sciences, I.R.C.C.S. "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo (FG), Italy.

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http://dx.doi.org/10.2174/1567205014666171110160556DOI Listing
February 2018

Looking Beyond the 5-HTTLPR Polymorphism: Genetic and Epigenetic Layers of Regulation Affecting the Serotonin Transporter Gene Expression.

Mol Neurobiol 2017 12 8;54(10):8386-8403. Epub 2016 Dec 8.

Institute of Translational Pharmacology (IFT), National Research Council (CNR), via Fosso del Cavaliere 100, 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s12035-016-0304-6DOI Listing
December 2017

Emerging biomarkers and screening for cognitive frailty.

Aging Clin Exp Res 2017 Dec 4;29(6):1075-1086. Epub 2017 Mar 4.

Shanghai Key Laboratory of Clinical Geriatrics, Department of Geriatrics, Huadong Hospital, and Research Center of Aging and Medicine, Shanghai Institute of Geriatrics and Gerontology, Shanghai Medical College, Fudan University, Shanghai, 200040, China.

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http://dx.doi.org/10.1007/s40520-017-0741-8DOI Listing
December 2017

Psychotropic drugs and CYP2D6 in late-life psychiatric and neurological disorders. What do we know?

Expert Opin Drug Saf 2017 Dec 12;16(12):1373-1385. Epub 2017 Oct 12.

a Complex Structure of Geriatrics, Department of Medical Sciences , IRCCS "Casa Sollievo della Sofferenza" , San Giovanni Rotondo , Foggia , Italy.

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http://dx.doi.org/10.1080/14740338.2017.1389891DOI Listing
December 2017

Additive Role of a Potentially Reversible Cognitive Frailty Model and Inflammatory State on the Risk of Disability: The Italian Longitudinal Study on Aging.

Am J Geriatr Psychiatry 2017 Nov 6;25(11):1236-1248. Epub 2017 Jul 6.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Gerontology-Geriatrics Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; Department of Clinical Research in Neurology, University of Bari Aldo Moro, Pia Fondazione Cardinale G. Panico, Tricase, Lecce, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2017.05.018DOI Listing
November 2017

Cognitive frailty: a potential target for secondary prevention of dementia.

Expert Opin Drug Metab Toxicol 2017 10 5;13(10):1023-1027. Epub 2017 Sep 5.

b Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , University of Bari Aldo Moro , Bari , Italy.

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http://dx.doi.org/10.1080/17425255.2017.1372424DOI Listing
October 2017

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Authors:
Rebecca Sims Sven J van der Lee Adam C Naj Céline Bellenguez Nandini Badarinarayan Johanna Jakobsdottir Brian W Kunkle Anne Boland Rachel Raybould Joshua C Bis Eden R Martin Benjamin Grenier-Boley Stefanie Heilmann-Heimbach Vincent Chouraki Amanda B Kuzma Kristel Sleegers Maria Vronskaya Agustin Ruiz Robert R Graham Robert Olaso Per Hoffmann Megan L Grove Badri N Vardarajan Mikko Hiltunen Markus M Nöthen Charles C White Kara L Hamilton-Nelson Jacques Epelbaum Wolfgang Maier Seung-Hoan Choi Gary W Beecham Cécile Dulary Stefan Herms Albert V Smith Cory C Funk Céline Derbois Andreas J Forstner Shahzad Ahmad Hongdong Li Delphine Bacq Denise Harold Claudia L Satizabal Otto Valladares Alessio Squassina Rhodri Thomas Jennifer A Brody Liming Qu Pascual Sánchez-Juan Taniesha Morgan Frank J Wolters Yi Zhao Florentino Sanchez Garcia Nicola Denning Myriam Fornage John Malamon Maria Candida Deniz Naranjo Elisa Majounie Thomas H Mosley Beth Dombroski David Wallon Michelle K Lupton Josée Dupuis Patrice Whitehead Laura Fratiglioni Christopher Medway Xueqiu Jian Shubhabrata Mukherjee Lina Keller Kristelle Brown Honghuang Lin Laura B Cantwell Francesco Panza Bernadette McGuinness Sonia Moreno-Grau Jeremy D Burgess Vincenzo Solfrizzi Petra Proitsi Hieab H Adams Mariet Allen Davide Seripa Pau Pastor L Adrienne Cupples Nathan D Price Didier Hannequin Ana Frank-García Daniel Levy Paramita Chakrabarty Paolo Caffarra Ina Giegling Alexa S Beiser Vilmantas Giedraitis Harald Hampel Melissa E Garcia Xue Wang Lars Lannfelt Patrizia Mecocci Gudny Eiriksdottir Paul K Crane Florence Pasquier Virginia Boccardi Isabel Henández Robert C Barber Martin Scherer Lluis Tarraga Perrie M Adams Markus Leber Yuning Chen Marilyn S Albert Steffi Riedel-Heller Valur Emilsson Duane Beekly Anne Braae Reinhold Schmidt Deborah Blacker Carlo Masullo Helena Schmidt Rachelle S Doody Gianfranco Spalletta W T Longstreth Thomas J Fairchild Paola Bossù Oscar L Lopez Matthew P Frosch Eleonora Sacchinelli Bernardino Ghetti Qiong Yang Ryan M Huebinger Frank Jessen Shuo Li M Ilyas Kamboh John Morris Oscar Sotolongo-Grau Mindy J Katz Chris Corcoran Melanie Dunstan Amy Braddel Charlene Thomas Alun Meggy Rachel Marshall Amy Gerrish Jade Chapman Miquel Aguilar Sarah Taylor Matt Hill Mònica Díez Fairén Angela Hodges Bruno Vellas Hilkka Soininen Iwona Kloszewska Makrina Daniilidou James Uphill Yogen Patel Joseph T Hughes Jenny Lord James Turton Annette M Hartmann Roberta Cecchetti Chiara Fenoglio Maria Serpente Marina Arcaro Carlo Caltagirone Maria Donata Orfei Antonio Ciaramella Sabrina Pichler Manuel Mayhaus Wei Gu Alberto Lleó Juan Fortea Rafael Blesa Imelda S Barber Keeley Brookes Chiara Cupidi Raffaele Giovanni Maletta David Carrell Sandro Sorbi Susanne Moebus Maria Urbano Alberto Pilotto Johannes Kornhuber Paolo Bosco Stephen Todd David Craig Janet Johnston Michael Gill Brian Lawlor Aoibhinn Lynch Nick C Fox John Hardy Roger L Albin Liana G Apostolova Steven E Arnold Sanjay Asthana Craig S Atwood Clinton T Baldwin Lisa L Barnes Sandra Barral Thomas G Beach James T Becker Eileen H Bigio Thomas D Bird Bradley F Boeve James D Bowen Adam Boxer James R Burke Jeffrey M Burns Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Cynthia M Carlsson Regina M Carney Minerva M Carrasquillo Steven L Carroll Carolina Ceballos Diaz Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Malcolm Dick Ranjan Duara Denis A Evans Kelley M Faber Kenneth B Fallon David W Fardo Martin R Farlow Steven Ferris Tatiana M Foroud Douglas R Galasko Marla Gearing Daniel H Geschwind John R Gilbert Neill R Graff-Radford Robert C Green John H Growdon Ronald L Hamilton Lindy E Harrell Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Erin Abner Lee-Way Jin Gyungah Jun Anna Karydas Jeffrey A Kaye Ronald Kim Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Kathryn L Lunetta Constantine G Lyketsos Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller John C Morris Jill R Murrell Amanda J Myers Sid O'Bryant John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson William Perry Elaine Peskind Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Howard J Rosen Roger N Rosenberg Mark A Sager Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Fabienne Garzia Feroze Golamaully Gislain Septier Sebastien Engelborghs Rik Vandenberghe Peter P De Deyn Carmen Muñoz Fernadez Yoland Aladro Benito Hakan Thonberg Charlotte Forsell Lena Lilius Anne Kinhult-Stählbom Lena Kilander RoseMarie Brundin Letizia Concari Seppo Helisalmi Anne Maria Koivisto Annakaisa Haapasalo Vincent Dermecourt Nathalie Fievet Olivier Hanon Carole Dufouil Alexis Brice Karen Ritchie Bruno Dubois Jayanadra J Himali C Dirk Keene JoAnn Tschanz Annette L Fitzpatrick Walter A Kukull Maria Norton Thor Aspelund Eric B Larson Ron Munger Jerome I Rotter Richard B Lipton María J Bullido Albert Hofman Thomas J Montine Eliecer Coto Eric Boerwinkle Ronald C Petersen Victoria Alvarez Fernando Rivadeneira Eric M Reiman Maura Gallo Christopher J O'Donnell Joan S Reisch Amalia Cecilia Bruni Donald R Royall Martin Dichgans Mary Sano Daniela Galimberti Peter St George-Hyslop Elio Scarpini Debby W Tsuang Michelangelo Mancuso Ubaldo Bonuccelli Ashley R Winslow Antonio Daniele Chuang-Kuo Wu Oliver Peters Benedetta Nacmias Matthias Riemenschneider Reinhard Heun Carol Brayne David C Rubinsztein Jose Bras Rita Guerreiro Ammar Al-Chalabi Christopher E Shaw John Collinge David Mann Magda Tsolaki Jordi Clarimón Rebecca Sussams Simon Lovestone Michael C O'Donovan Michael J Owen Timothy W Behrens Simon Mead Alison M Goate Andre G Uitterlinden Clive Holmes Carlos Cruchaga Martin Ingelsson David A Bennett John Powell Todd E Golde Caroline Graff Philip L De Jager Kevin Morgan Nilufer Ertekin-Taner Onofre Combarros Bruce M Psaty Peter Passmore Steven G Younkin Claudine Berr Vilmundur Gudnason Dan Rujescu Dennis W Dickson Jean-François Dartigues Anita L DeStefano Sara Ortega-Cubero Hakon Hakonarson Dominique Campion Merce Boada John Keoni Kauwe Lindsay A Farrer Christine Van Broeckhoven M Arfan Ikram Lesley Jones Jonathan L Haines Christophe Tzourio Lenore J Launer Valentina Escott-Price Richard Mayeux Jean-François Deleuze Najaf Amin Peter A Holmans Margaret A Pericak-Vance Philippe Amouyel Cornelia M van Duijn Alfredo Ramirez Li-San Wang Jean-Charles Lambert Sudha Seshadri Julie Williams Gerard D Schellenberg

Nat Genet 2017 09 17;49(9):1373-1384. Epub 2017 Jul 17.

Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1038/ng.3916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5669039PMC
September 2017

Clinical and genetic analyses of familial and sporadic frontotemporal dementia patients in Southern Italy.

Alzheimers Dement 2017 Aug 3;13(8):858-869. Epub 2017 Mar 3.

Department of Clinical Research in Neurology, University of Bari, "Pia Fondazione Cardinale G. Panico", Lecce, Italy; Neurodegenerative Diseases Unit, Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari, Bari, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.01.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232845PMC
August 2017

Information and Communication Technologies for the Activities of Daily Living in Older Patients with Dementia: A Systematic Review.

J Alzheimers Dis 2017 ;57(3):927-935

Department of Medical Sciences, Geriatric Unit and Laboratory of Gerontology and Geriatrics, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.3233/JAD-161145DOI Listing
August 2017

Efficacy and Safety of Long-Term Administration of Tapentadol in Relieving Chronic Pancreatitis Pain.

Pain Med 2017 04;18(4):815-817

Division of GastroenterologyGeriatric Unit & Gerontology-Geriatrics Research LaboratoryDepartment of Anesthesiology, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy.

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http://dx.doi.org/10.1093/pm/pnw220DOI Listing
April 2017

Klotho Gene and Selective Serotonin Reuptake Inhibitors: Response to Treatment in Late-Life Major Depressive Disorder.

Mol Neurobiol 2017 03 3;54(2):1340-1351. Epub 2016 Feb 3.

Gerontology-Geriatric Research Laboratory, Department of Medical Sciences, I.R.C.C.S. "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.1007/s12035-016-9711-yDOI Listing
March 2017

Pharmacogenetics of neurological and psychiatric diseases at older age: has the time come?

Expert Opin Drug Metab Toxicol 2017 Mar 20;13(3):259-277. Epub 2016 Oct 20.

c Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences , IRCCS Casa Sollievo della Sofferenza , San Giovanni Rotondo , Italy.

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http://dx.doi.org/10.1080/17425255.2017.1246533DOI Listing
March 2017

Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's Disease.

Biomed Res Int 2016 26;2016:3245935. Epub 2016 Jun 26.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Department of Clinical Research in Neurology, University of Bari Aldo Moro, "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy.

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http://dx.doi.org/10.1155/2016/3245935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4939203PMC
February 2017

Reversible Cognitive Frailty, Dementia, and All-Cause Mortality. The Italian Longitudinal Study on Aging.

J Am Med Dir Assoc 2017 01;18(1):89.e1-89.e8

Gerontology-Geriatrics Research Laboratory, Istituto di Ricovero e Cura a Carattere Scientifico Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Department of Clinical Research in Neurology, University of Bari Aldo Moro, Pia Fondazione Cardinale G. Panico, Tricase, Lecce, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.jamda.2016.10.012DOI Listing
January 2017

Tau-directed approaches for the treatment of Alzheimer's disease: focus on leuco-methylthioninium.

Expert Rev Neurother 2016 ;16(3):259-77

a Geriatric Unit & Laboratory of Gerontology and Geriatrics, Department of Medical Sciences , IRCCS 'Casa Sollievo della Sofferenza' , San Giovanni Rotondo , Foggia , Italy.

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http://dx.doi.org/10.1586/14737175.2016.1140039DOI Listing
December 2016

Delusions in Patients with Alzheimer's Disease: A Multidimensional Approach.

J Alzheimers Dis 2016 ;51(2):427-37

Geriatric Unit & Laboratory of Gerontology and Geriatrics, Department of Medical Sciences, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.3233/JAD-150944DOI Listing
December 2016

Psychiatry meets pharmacogenetics for the treatment of revolving door patients with psychiatric disorders.

Expert Rev Neurother 2016 12 11;16(12):1357-1369. Epub 2016 Jul 11.

a Geriatric Unit and Geriatric Research Laboratory, Department of Medical Sciences , IRCCS Casa Sollievo della Sofferenza , Foggia , Italy.

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http://dx.doi.org/10.1080/14737175.2016.1204913DOI Listing
December 2016

Emerging drugs to reduce abnormal β-amyloid protein in Alzheimer's disease patients.

Expert Opin Emerg Drugs 2016 Dec 6;21(4):377-391. Epub 2016 Oct 6.

a Unit of Neurodegenerative Disease, Department of Basic Medicine Sciences, Neuroscience, and Sense Organs , University of Bari 'Aldo Moro' , Bari , Italy.

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http://dx.doi.org/10.1080/14728214.2016.1241232DOI Listing
December 2016

Role of the 5-HTTLPR and SNP Promoter Polymorphisms on Serotonin Transporter Gene Expression: a Closer Look at Genetic Architecture and In Vitro Functional Studies of Common and Uncommon Allelic Variants.

Mol Neurobiol 2016 10 13;53(8):5510-26. Epub 2015 Oct 13.

National Research Council (CNR), Institute of Translational Pharmacology (IFT), via Fosso del Cavaliere 100, 00133, Rome, Italy.

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http://dx.doi.org/10.1007/s12035-015-9409-6DOI Listing
October 2016

Tau-based therapeutics for Alzheimer's disease: active and passive immunotherapy.

Immunotherapy 2016 09;8(9):1119-34

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, & Sense Organs, University of Bari Aldo Moro, Bari, Italy.

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http://dx.doi.org/10.2217/imt-2016-0019DOI Listing
September 2016

High doses of incobotulinumtoxinA for the treatment of post-stroke spasticity: are they safe and effective?

Expert Opin Drug Metab Toxicol 2016 Aug 17;12(8):843-6. Epub 2016 Jun 17.

c Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , University of Bari Aldo Moro , Bari , Italy.

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http://dx.doi.org/10.1080/17425255.2016.1198318DOI Listing
August 2016

Targeting Cognitive Frailty: Clinical and Neurobiological Roadmap for a Single Complex Phenotype.

J Alzheimers Dis 2015 ;47(4):793-813

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy.

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http://dx.doi.org/10.3233/JAD-150358DOI Listing
July 2016

Coffee Consumption Habits and the Risk of Mild Cognitive Impairment: The Italian Longitudinal Study on Aging.

J Alzheimers Dis 2015 ;47(4):889-99

Population Health and Health Determinants Unit, National Centre for Epidemiology, Surveillance and Health Promotion (CNESPS), Istituto Superiore di Sanità (ISS), Roma, Italy.

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http://dx.doi.org/10.3233/JAD-150333DOI Listing
July 2016

Progresses in treating agitation: a major clinical challenge in Alzheimer's disease.

Expert Opin Pharmacother 2015 21;16(17):2581-8. Epub 2015 Sep 21.

a 1 University of Bari Aldo Moro, Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , Bari, Italy ,

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http://dx.doi.org/10.1517/14656566.2015.1092520DOI Listing
June 2016

Tau aggregation inhibitors: the future of Alzheimer's pharmacotherapy?

Expert Opin Pharmacother 2016 15;17(4):457-61. Epub 2016 Feb 15.

a Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , University of Bari Aldo Moro , Bari , Italy.

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http://dx.doi.org/10.1517/14656566.2016.1146686DOI Listing
June 2016

Can a Positive Allosteric Modulation of GABAergic Receptors Improve Motor Symptoms in Patients with Parkinson's Disease? The Potential Role of Zolpidem in the Treatment of Parkinson's Disease.

Parkinsons Dis 2016 17;2016:2531812. Epub 2016 May 17.

Geriatric Unit and Laboratory of Gerontology and Geriatrics, Department of Medical Sciences, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, 71013 Foggia, Italy.

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http://dx.doi.org/10.1155/2016/2531812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886078PMC
June 2016

Genetic Profile, Environmental Exposure, and Their Interaction in Parkinson's Disease.

Parkinsons Dis 2016 31;2016:6465793. Epub 2016 Jan 31.

Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy.

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http://dx.doi.org/10.1155/2016/6465793DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752982PMC
March 2016

Postural and Balance Disorders in Patients with Parkinson's Disease: A Prospective Open-Label Feasibility Study with Two Months of Action Observation Treatment.

Parkinsons Dis 2015 22;2015:902738. Epub 2015 Dec 22.

Geriatric Unit & Laboratory of Gerontology and Geriatrics, Department of Medical Sciences, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, 71013 Foggia, Italy; Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, 70124 Bari, Italy; Department of Clinical Research in Neurology, University of Bari Aldo Moro, "Pia Fondazione Cardinale G. Panico", Tricase, 73039 Lecce, Italy.

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http://dx.doi.org/10.1155/2015/902738DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4700184PMC
January 2016

Cognitive Frailty: A Systematic Review of Epidemiological and Neurobiological Evidence of an Age-Related Clinical Condition.

Rejuvenation Res 2015 Oct 20;18(5):389-412. Epub 2015 Aug 20.

3 Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro , Bari, Italy .

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http://dx.doi.org/10.1089/rej.2014.1637DOI Listing
October 2015

Role of CYP2D6 Polymorphisms in the Outcome of Postoperative Pain Treatment.

Pain Med 2015 Oct 19;16(10):2012-23. Epub 2015 May 19.

Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy.

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http://dx.doi.org/10.1111/pme.12778DOI Listing
October 2015

Serum paraoxonase and arylesterase activities of paraoxonase-1 (PON-1), mild cognitive impairment, and 2-year conversion to dementia: A pilot study.

J Neurochem 2015 Oct 3;135(2):395-401. Epub 2015 Aug 3.

Section of Internal and Cardiopulmonary Medicine, Department of Medical Science, University of Ferrara, Ferrara, Italy.

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http://dx.doi.org/10.1111/jnc.13240DOI Listing
October 2015

Measuring pharmacogenetics in special groups: geriatrics.

Expert Opin Drug Metab Toxicol 2015 Jul 19;11(7):1073-88. Epub 2015 May 19.

IRCCS Casa Sollievo della Sofferenza, Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences , San Giovanni Rotondo, Foggia , Italy

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http://dx.doi.org/10.1517/17425255.2015.1041919DOI Listing
July 2015

Age-related hearing impairment and frailty in Alzheimer's disease: interconnected associations and mechanisms.

Front Aging Neurosci 2015 9;7:113. Epub 2015 Jun 9.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro Bari, Italy ; Department of Clinical Research in Neurology, University of Bari Aldo Moro, "Pia Fondazione Cardinale G. Panico" Tricase, Italy.

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http://dx.doi.org/10.3389/fnagi.2015.00113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460423PMC
June 2015

Frailty, disability and physical exercise in the aging process and in chronic kidney disease.

Kidney Blood Press Res 2014 29;39(2-3):164-8. Epub 2014 Jul 29.

Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy.

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http://dx.doi.org/10.1159/000355792DOI Listing
May 2015

Role of the serotonin transporter gene locus in the response to SSRI treatment of major depressive disorder in late life.

J Psychopharmacol 2015 May 31;29(5):623-33. Epub 2015 Mar 31.

Department of Medical Sciences, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy Geriatrics Unit, San Antonio Hospital, Padova, Italy.

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http://dx.doi.org/10.1177/0269881115578159DOI Listing
May 2015

FOXO1 locus and acetylcholinesterase inhibitors in elderly patients with Alzheimer's disease.

Clin Interv Aging 2014 21;9:1783-91. Epub 2014 Oct 21.

Gerontology and Geriatrics Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy ; Geriatrics Unit, Azienda ULSS 16 Padova, San Antonio Hospital, Padova, Italy.

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http://dx.doi.org/10.2147/CIA.S64758DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211854PMC
April 2015

Functional genetic variation in the serotonin 5-HTTLPR modulates brain damage in frontotemporal dementia.

Neurobiol Aging 2015 Jan 15;36(1):446-51. Epub 2014 Jul 15.

Centre for Ageing Brain and Neurodegenerative Disorders, Neurology Unit, University of Brescia, Brescia, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01974580140047
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http://dx.doi.org/10.1016/j.neurobiolaging.2014.07.008DOI Listing
January 2015

Systemic oxidative stress and conversion to dementia of elderly patients with mild cognitive impairment.

Biomed Res Int 2014 12;2014:309507. Epub 2014 Jan 12.

Section of Internal Medicine, Gerontology, and Clinical Nutrition, Department of Medical Science, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy.

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http://dx.doi.org/10.1155/2014/309507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3913282PMC
December 2014

Efficacy and safety studies of gantenerumab in patients with Alzheimer's disease.

Expert Rev Neurother 2014 Sep 1;14(9):973-86. Epub 2014 Aug 1.

Department of Basic Medicine, Neuroscience, and Sense Organs, Neurodegenerative Disease Unit, University of Bari Aldo Moro, Bari, Italy.

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http://dx.doi.org/10.1586/14737175.2014.945522DOI Listing
September 2014

Nutrition, frailty, and Alzheimer's disease.

Front Aging Neurosci 2014 26;6:221. Epub 2014 Aug 26.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro Bari, Italy ; Department of Clinical Research in Neurology, University of Bari Aldo Moro, "Pia Fondazione Cardinale G. Panico" Lecce, Italy.

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http://dx.doi.org/10.3389/fnagi.2014.00221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143595PMC
September 2014

Oxidative balance, homocysteine, and uric acid levels in older patients with Late Onset Alzheimer's Disease or Vascular Dementia.

J Neurol Sci 2014 Feb 4;337(1-2):156-61. Epub 2013 Dec 4.

Department of Medical Science, Section of Internal Medicine, Gerontology, and Clinical Nutrition, University of Ferrara, 44100 Ferrara, Italy.

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http://dx.doi.org/10.1016/j.jns.2013.11.041DOI Listing
February 2014

[Forkhead-box-O1 locus and metabolic markers in the elderly: an association study].

Rev Esp Geriatr Gerontol 2012 Nov-Dec;47(6):254-8. Epub 2012 Oct 8.

Unidad Geriátrica y Laboratorio de Investigación de Gerontología y Geriatría, Departamento de Ciencias Médicas, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italia.

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http://dx.doi.org/10.1016/j.regg.2012.06.004DOI Listing
December 2013

TOMM40, APOE, and APOC1 in primary progressive aphasia and frontotemporal dementia.

J Alzheimers Dis 2012 ;31(4):731-40

Gerontology and Geriatrics Research Laboratory, I.R.C.C.S. Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.

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http://dx.doi.org/10.3233/JAD-2012-120403DOI Listing
July 2013

Pharmacogenetics in older people: what we know and what we need to know.

J Nephrol 2012 ;25 Suppl 19:S38-47

Gerontology and Geriatric Research Laboratory, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.5301/jn.5000137DOI Listing
June 2013

The serotonin transporter gene locus in late-life major depressive disorder.

Am J Geriatr Psychiatry 2013 Jan 2;21(1):67-77. Epub 2013 Jan 2.

Geriatric Unit & Gerontology-Geriatric Research Laboratory, Department of Medical Sciences, Institute of Care and Scientific Research Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.1016/j.jagp.2012.10.012DOI Listing
January 2013

Alcohol consumption in mild cognitive impairment and dementia: harmful or neuroprotective?

Int J Geriatr Psychiatry 2012 Dec 7;27(12):1218-38. Epub 2012 Mar 7.

Geriatric Unit and Gerontology-Geriatric Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.

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http://dx.doi.org/10.1002/gps.3772DOI Listing
December 2012

Current epidemiological approaches to the metabolic-cognitive syndrome.

J Alzheimers Dis 2012 ;30 Suppl 2:S31-75

Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.3233/JAD-2012-111496DOI Listing
December 2012

FOXP2, APOE, and PRNP: new modulators in primary progressive aphasia.

J Alzheimers Dis 2012 ;28(4):941-50

Centre for Ageing Brain and Neurodegenerative Disorders, Neurology Unit, University of Brescia, Brescia, Italy.

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http://dx.doi.org/10.3233/JAD-2011-111541DOI Listing
September 2012

Neuropsychiatric symptoms and functional status in Alzheimer's disease and vascular dementia patients.

Curr Alzheimer Res 2012 Jul;9(6):759-71

Geriatric Unit & Laboratory of Gerontology and Geriatrics, Department of Medical Sciences, I.R.C.C.S. Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.

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July 2012

Effectiveness of a high-throughput genetic analysis in the identification of responders/non-responders to CYP2D6-metabolized drugs.

Clin Lab 2011 ;57(11-12):887-93

Laboratory of Clinical Chemistry, Department of Clinical Pathology, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy.

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February 2012

Solanezumab for the treatment of mild-to-moderate Alzheimer's disease.

Expert Rev Clin Immunol 2012 Feb;8(2):135-49

Research and Development Department, Chiesi Farmaceutici, Parma, Italy.

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http://dx.doi.org/10.1586/eci.11.93DOI Listing
February 2012

Immunotherapy for Alzheimer's disease: from anti-β-amyloid to tau-based immunization strategies.

Immunotherapy 2012 Feb;4(2):213-38

Geriatric Unit & Gerontology-Geriatric Research Laboratory, IRCCS Casa Sollievo della Sofferenza, Foggia, Italy.

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http://dx.doi.org/10.2217/imt.11.170DOI Listing
February 2012

Advances in the identification of γ-secretase inhibitors for the treatment of Alzheimer's disease.

Expert Opin Drug Discov 2012 Jan 14;7(1):19-37. Epub 2011 Dec 14.

IRCCS Casa Sollievo della Sofferenza, Geriatric Unit and Gerontology-Geriatric Research Laboratory, San Giovanni Rotondo, Foggia, Italy.

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http://dx.doi.org/10.1517/17460441.2012.645534DOI Listing
January 2012

The APOE polymorphism in Alzheimer's disease patients with neuropsychiatric symptoms and syndromes.

Int J Geriatr Psychiatry 2011 Oct 29;26(10):1062-70. Epub 2010 Oct 29.

Geriatrics Unit and Gerontology-Geriatric Research Laboratory, Department of Medical Sciences, IRCCS 'Casa Sollievo della Sofferenza', San Giovanni Rotondo, FG, Italy.

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http://dx.doi.org/10.1002/gps.2644DOI Listing
October 2011

The genetics of the human APOE polymorphism.

Rejuvenation Res 2011 Oct 29;14(5):491-500. Epub 2011 Sep 29.

Geriatric Unit & Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy.

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http://dx.doi.org/10.1089/rej.2011.1169DOI Listing
October 2011