Publications by authors named "Davide Seripa"

100Publications

Anti-amyloid-β protein agents for the treatment of Alzheimer's disease: an update on emerging drugs.

Expert Opin Emerg Drugs 2020 09 20;25(3):319-335. Epub 2020 Aug 20.

Population Health Unit - "Salus in Apulia Study" - National Institute of Gastroenterology, "Saverio De Bellis", Research Hospital , Bari, Italy.

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September 2020

Can pharmacotherapy effectively reduce Alzheimer's related agitation?

Expert Opin Pharmacother 2020 09 1;21(13):1517-1522. Epub 2020 Jun 1.

Frailty Phenotypes Research Unit, "Salus in Apulia Study", National Institute of Gastroenterology "Saverio de Bellis", Research Hospital , Bari, Italy.

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September 2020

The Challenge of Antidepressant Therapeutics in Alzheimer's Disease.

Adv Exp Med Biol 2020 ;1260:267-281

Unit of Epidemiological Research on Aging, National Institute of Gastroenterology 'Saverio de Bellis', Research Hospital, Castellana Grotte, Bari, Italy.

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June 2020

Development of disease-modifying drugs for frontotemporal dementia spectrum disorders.

Nat Rev Neurol 2020 04 23;16(4):213-228. Epub 2020 Mar 23.

Department of Research and Development, Chiesi Farmaceutici, Parma, Italy.

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April 2020

Autophagy and mitophagy biomarkers are reduced in sera of patients with Alzheimer's disease and mild cognitive impairment.

Sci Rep 2019 12 27;9(1):20009. Epub 2019 Dec 27.

Department of Morphology, Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, Laboratory for Technologies of Advanced Therapies (LTTA), University of Ferrara, Ferrara, Italy.

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December 2019

Corrigendum to "Nutritional interventions and cognitive-related outcomes in patients with late-life cognitive disorders: A systematic review" Neurosci. Biobehav. Rev. 95 (2018) 480-498.

Neurosci Biobehav Rev 2020 Jan 5;108:889. Epub 2019 Dec 5.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Geriatric Unit & Laboratory of Gerontology and Geriatrics, Department of Medical Sciences, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy; Department of Clinical Research in Neurology, University of Bari Aldo Moro, "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy. Electronic address:

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January 2020

Serum beta-secretase 1 (BACE1) activity as candidate biomarker for late-onset Alzheimer's disease.

Geroscience 2020 02 19;42(1):159-167. Epub 2019 Nov 19.

Department of Morphology, Surgery, and Medical Sciences, University of Ferrara, Via Luigi Borsari 46, 44121, Ferrara, Italy.

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February 2020

Pharmacogenetics in the clinical analysis laboratory: clinical practice, research, and drug development pipeline.

Expert Opin Drug Metab Toxicol 2019 Sep 12;15(9):751-765. Epub 2019 Sep 12.

Research Laboratory, Complex Structure of Geriatrics, Department of Medical Sciences, Fondazione IRCCS Casa Sollievo della Sofferenza , Foggia , Italy.

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September 2019

Biopsychosocial frailty and the risk of incident dementia: The Italian longitudinal study on aging.

Alzheimers Dement 2019 08 2;15(8):1019-1028. Epub 2019 Jul 2.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; National Institute of Gastroenterology "Saverio de Bellis", Research Hospital, Castellana Grotte, Bari, Italy; Geriatric Unit, Fondazione IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy. Electronic address:

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August 2019

The Age-Related Central Auditory Processing Disorder: Silent Impairment of the Cognitive Ear.

Front Neurosci 2019 14;13:619. Epub 2019 Jun 14.

Otolaryngology Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy.

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June 2019

Promising therapies for the treatment of frontotemporal dementia clinical phenotypes: from symptomatic to disease-modifying drugs.

Expert Opin Pharmacother 2019 06 19;20(9):1091-1107. Epub 2019 Apr 19.

a Neurodegenerative Disease Unit, Department of Basic Medical Sciences, Neuroscience and Sense Organs , University of Bari "Aldo Moro" , Bari , Italy.

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June 2019

Disease-modifying therapies for tauopathies: agents in the pipeline.

Expert Rev Neurother 2019 05 25;19(5):397-408. Epub 2019 Apr 25.

g Department of Neurological Sciences , Santa Maria University Hospital , Terni , Italy.

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May 2019

Understanding the Amyloid Hypothesis in Alzheimer's Disease.

J Alzheimers Dis 2019 ;68(2):493-510

Research Laboratory, Complex Structure of Geriatrics, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.

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July 2020

The Role of Biomarkers in Psychiatry.

Adv Exp Med Biol 2019;1118:135-162

Neurodegenerative Disease Unit, Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy.

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August 2019

Amyloid-β immunotherapy for alzheimer disease: Is it now a long shot?

Ann Neurol 2019 03 28;85(3):303-315. Epub 2019 Jan 28.

Department of Research and Development, Chiesi Pharmaceuticals, Parma, Italy.

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March 2019

Nutritional interventions and cognitive-related outcomes in patients with late-life cognitive disorders: A systematic review.

Neurosci Biobehav Rev 2018 12 3;95:480-498. Epub 2018 Nov 3.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Geriatric Unit, Fondazione IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy; Department of Clinical Research in Neurology, Center for Neurodegenerative Diseases and the Aging Brain, University of Bari "Aldo Moro", "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy. Electronic address:

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December 2018

Testing a Combination of Markers of Systemic Redox Status as a Possible Tool for the Diagnosis of Late Onset Alzheimer's Disease.

Dis Markers 2018 9;2018:2576026. Epub 2018 Sep 9.

Department of Biomedical and Specialist Surgical Sciences, Section of Medical Biochemistry, Molecular Biology and Genetics, University of Ferrara, Via Luigi Borsari 46, 44121 Ferrara, Italy.

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January 2019

CYP2D6 genotypes in revolving door patients with bipolar disorders: A case series.

Medicine (Baltimore) 2018 Sep;97(37):e11998

Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari "Aldo Moro", Bari Laboratory of Clinical Chemistry, Department of Clinical Pathology, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo Psychiatric Unit, Department of Clinical and Experimental Medicine, University of Foggia, Foggia Institute of Neurology, Catholic University of Sacred Heart, Rome Department of Clinical Research in Neurology, Neurodegenerative Disease Unit, University of Bari "Aldo Moro", Azienda Ospedaliera "Card. G. Panico", Tricase, Lecce, Italy.

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September 2018

Late-Life Depression versus Amnestic Mild Cognitive Impairment: Alzheimer's Disease Incidence in 4 Years of Follow-Up.

Dement Geriatr Cogn Disord 2018 10;46(3-4):140-153. Epub 2018 Sep 10.

Complex Unit of Geriatrics, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.

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January 2019

Plasma β-amyloid reference values in cognitively normal subjects.

J Neurol Sci 2018 08 13;391:120-126. Epub 2018 Jun 13.

Unit of Neurodegenerative Disease, Department of Clinical Research in Neurology, University of Bari "Aldo Moro" at "Pia Fondazione Card. G. Panico", Tricase, Lecce, Italy; Unit of Neurodegenerative Disease, Department of Basic Medicine Sciences, Neuroscience, and Sense Organs, University of Bari "Aldo Moro", Bari, Italy. Electronic address:

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August 2018

Klotho at the Edge of Alzheimer's Disease and Senile Depression.

Mol Neurobiol 2019 Mar 5;56(3):1908-1920. Epub 2018 Jul 5.

Department of Medical Sciences, Division of Internal Medicine and Chronobiology Unit, IRCCS Scientific Institute and Regional General Hospital "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Italy.

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March 2019

Neurocognitive Disorders and Dehydration in Older Patients: Clinical Experience Supports the Hydromolecular Hypothesis of Dementia.

Nutrients 2018 May 3;10(5). Epub 2018 May 3.

Complex Structure of Geriatrics, Department of Medical Sciences, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Viale Cappuccini 1, 71013 Foggia, Italy.

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May 2018

Gene-gene interactions among coding genes of iron-homeostasis proteins and APOE-alleles in cognitive impairment diseases.

PLoS One 2018 8;13(3):e0193867. Epub 2018 Mar 8.

Department of Biomedical and Specialty Surgical Sciences, and Section of Medical Biochemistry, Molecular Biology & Genetics and Ctr. Hemostasis & Thrombosis, University of Ferrara, Ferrara, Italy.

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July 2018

Erythrocyte Associated Amyloid-β as Potential Biomarker to Diagnose Dementia.

Curr Alzheimer Res 2018 02;15(4):381-385

Complex Unit of Geriatrics, Department of Medical Sciences, I.R.C.C.S. "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo (FG), Italy.

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February 2018

Psychotropic drugs and CYP2D6 in late-life psychiatric and neurological disorders. What do we know?

Expert Opin Drug Saf 2017 Dec 12;16(12):1373-1385. Epub 2017 Oct 12.

a Complex Structure of Geriatrics, Department of Medical Sciences , IRCCS "Casa Sollievo della Sofferenza" , San Giovanni Rotondo , Foggia , Italy.

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December 2017

Cognitive frailty: a potential target for secondary prevention of dementia.

Expert Opin Drug Metab Toxicol 2017 10 5;13(10):1023-1027. Epub 2017 Sep 5.

b Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , University of Bari Aldo Moro , Bari , Italy.

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October 2017

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Authors:
Rebecca Sims Sven J van der Lee Adam C Naj Céline Bellenguez Nandini Badarinarayan Johanna Jakobsdottir Brian W Kunkle Anne Boland Rachel Raybould Joshua C Bis Eden R Martin Benjamin Grenier-Boley Stefanie Heilmann-Heimbach Vincent Chouraki Amanda B Kuzma Kristel Sleegers Maria Vronskaya Agustin Ruiz Robert R Graham Robert Olaso Per Hoffmann Megan L Grove Badri N Vardarajan Mikko Hiltunen Markus M Nöthen Charles C White Kara L Hamilton-Nelson Jacques Epelbaum Wolfgang Maier Seung-Hoan Choi Gary W Beecham Cécile Dulary Stefan Herms Albert V Smith Cory C Funk Céline Derbois Andreas J Forstner Shahzad Ahmad Hongdong Li Delphine Bacq Denise Harold Claudia L Satizabal Otto Valladares Alessio Squassina Rhodri Thomas Jennifer A Brody Liming Qu Pascual Sánchez-Juan Taniesha Morgan Frank J Wolters Yi Zhao Florentino Sanchez Garcia Nicola Denning Myriam Fornage John Malamon Maria Candida Deniz Naranjo Elisa Majounie Thomas H Mosley Beth Dombroski David Wallon Michelle K Lupton Josée Dupuis Patrice Whitehead Laura Fratiglioni Christopher Medway Xueqiu Jian Shubhabrata Mukherjee Lina Keller Kristelle Brown Honghuang Lin Laura B Cantwell Francesco Panza Bernadette McGuinness Sonia Moreno-Grau Jeremy D Burgess Vincenzo Solfrizzi Petra Proitsi Hieab H Adams Mariet Allen Davide Seripa Pau Pastor L Adrienne Cupples Nathan D Price Didier Hannequin Ana Frank-García Daniel Levy Paramita Chakrabarty Paolo Caffarra Ina Giegling Alexa S Beiser Vilmantas Giedraitis Harald Hampel Melissa E Garcia Xue Wang Lars Lannfelt Patrizia Mecocci Gudny Eiriksdottir Paul K Crane Florence Pasquier Virginia Boccardi Isabel Henández Robert C Barber Martin Scherer Lluis Tarraga Perrie M Adams Markus Leber Yuning Chen Marilyn S Albert Steffi Riedel-Heller Valur Emilsson Duane Beekly Anne Braae Reinhold Schmidt Deborah Blacker Carlo Masullo Helena Schmidt Rachelle S Doody Gianfranco Spalletta W T Longstreth Thomas J Fairchild Paola Bossù Oscar L Lopez Matthew P Frosch Eleonora Sacchinelli Bernardino Ghetti Qiong Yang Ryan M Huebinger Frank Jessen Shuo Li M Ilyas Kamboh John Morris Oscar Sotolongo-Grau Mindy J Katz Chris Corcoran Melanie Dunstan Amy Braddel Charlene Thomas Alun Meggy Rachel Marshall Amy Gerrish Jade Chapman Miquel Aguilar Sarah Taylor Matt Hill Mònica Díez Fairén Angela Hodges Bruno Vellas Hilkka Soininen Iwona Kloszewska Makrina Daniilidou James Uphill Yogen Patel Joseph T Hughes Jenny Lord James Turton Annette M Hartmann Roberta Cecchetti Chiara Fenoglio Maria Serpente Marina Arcaro Carlo Caltagirone Maria Donata Orfei Antonio Ciaramella Sabrina Pichler Manuel Mayhaus Wei Gu Alberto Lleó Juan Fortea Rafael Blesa Imelda S Barber Keeley Brookes Chiara Cupidi Raffaele Giovanni Maletta David Carrell Sandro Sorbi Susanne Moebus Maria Urbano Alberto Pilotto Johannes Kornhuber Paolo Bosco Stephen Todd David Craig Janet Johnston Michael Gill Brian Lawlor Aoibhinn Lynch Nick C Fox John Hardy Roger L Albin Liana G Apostolova Steven E Arnold Sanjay Asthana Craig S Atwood Clinton T Baldwin Lisa L Barnes Sandra Barral Thomas G Beach James T Becker Eileen H Bigio Thomas D Bird Bradley F Boeve James D Bowen Adam Boxer James R Burke Jeffrey M Burns Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Cynthia M Carlsson Regina M Carney Minerva M Carrasquillo Steven L Carroll Carolina Ceballos Diaz Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Malcolm Dick Ranjan Duara Denis A Evans Kelley M Faber Kenneth B Fallon David W Fardo Martin R Farlow Steven Ferris Tatiana M Foroud Douglas R Galasko Marla Gearing Daniel H Geschwind John R Gilbert Neill R Graff-Radford Robert C Green John H Growdon Ronald L Hamilton Lindy E Harrell Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Erin Abner Lee-Way Jin Gyungah Jun Anna Karydas Jeffrey A Kaye Ronald Kim Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Kathryn L Lunetta Constantine G Lyketsos Daniel C Marson Frank Martiniuk Deborah C Mash Eliezer Masliah Wayne C McCormick Susan M McCurry Andrew N McDavid Ann C McKee Marsel Mesulam Bruce L Miller Carol A Miller Joshua W Miller John C Morris Jill R Murrell Amanda J Myers Sid O'Bryant John M Olichney Vernon S Pankratz Joseph E Parisi Henry L Paulson William Perry Elaine Peskind Aimee Pierce Wayne W Poon Huntington Potter Joseph F Quinn Ashok Raj Murray Raskind Barry Reisberg Christiane Reitz John M Ringman Erik D Roberson Ekaterina Rogaeva Howard J Rosen Roger N Rosenberg Mark A Sager Andrew J Saykin Julie A Schneider Lon S Schneider William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Rudolph E Tanzi Tricia A Thornton-Wells John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Fabienne Garzia Feroze Golamaully Gislain Septier Sebastien Engelborghs Rik Vandenberghe Peter P De Deyn Carmen Muñoz Fernadez Yoland Aladro Benito Hakan Thonberg Charlotte Forsell Lena Lilius Anne Kinhult-Stählbom Lena Kilander RoseMarie Brundin Letizia Concari Seppo Helisalmi Anne Maria Koivisto Annakaisa Haapasalo Vincent Dermecourt Nathalie Fievet Olivier Hanon Carole Dufouil Alexis Brice Karen Ritchie Bruno Dubois Jayanadra J Himali C Dirk Keene JoAnn Tschanz Annette L Fitzpatrick Walter A Kukull Maria Norton Thor Aspelund Eric B Larson Ron Munger Jerome I Rotter Richard B Lipton María J Bullido Albert Hofman Thomas J Montine Eliecer Coto Eric Boerwinkle Ronald C Petersen Victoria Alvarez Fernando Rivadeneira Eric M Reiman Maura Gallo Christopher J O'Donnell Joan S Reisch Amalia Cecilia Bruni Donald R Royall Martin Dichgans Mary Sano Daniela Galimberti Peter St George-Hyslop Elio Scarpini Debby W Tsuang Michelangelo Mancuso Ubaldo Bonuccelli Ashley R Winslow Antonio Daniele Chuang-Kuo Wu Oliver Peters Benedetta Nacmias Matthias Riemenschneider Reinhard Heun Carol Brayne David C Rubinsztein Jose Bras Rita Guerreiro Ammar Al-Chalabi Christopher E Shaw John Collinge David Mann Magda Tsolaki Jordi Clarimón Rebecca Sussams Simon Lovestone Michael C O'Donovan Michael J Owen Timothy W Behrens Simon Mead Alison M Goate Andre G Uitterlinden Clive Holmes Carlos Cruchaga Martin Ingelsson David A Bennett John Powell Todd E Golde Caroline Graff Philip L De Jager Kevin Morgan Nilufer Ertekin-Taner Onofre Combarros Bruce M Psaty Peter Passmore Steven G Younkin Claudine Berr Vilmundur Gudnason Dan Rujescu Dennis W Dickson Jean-François Dartigues Anita L DeStefano Sara Ortega-Cubero Hakon Hakonarson Dominique Campion Merce Boada John Keoni Kauwe Lindsay A Farrer Christine Van Broeckhoven M Arfan Ikram Lesley Jones Jonathan L Haines Christophe Tzourio Lenore J Launer Valentina Escott-Price Richard Mayeux Jean-François Deleuze Najaf Amin Peter A Holmans Margaret A Pericak-Vance Philippe Amouyel Cornelia M van Duijn Alfredo Ramirez Li-San Wang Jean-Charles Lambert Sudha Seshadri Julie Williams Gerard D Schellenberg

Nat Genet 2017 09 17;49(9):1373-1384. Epub 2017 Jul 17.

Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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September 2017

Additive Role of a Potentially Reversible Cognitive Frailty Model and Inflammatory State on the Risk of Disability: The Italian Longitudinal Study on Aging.

Am J Geriatr Psychiatry 2017 Nov 6;25(11):1236-1248. Epub 2017 Jul 6.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Gerontology-Geriatrics Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; Department of Clinical Research in Neurology, University of Bari Aldo Moro, Pia Fondazione Cardinale G. Panico, Tricase, Lecce, Italy. Electronic address:

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November 2017

Role of CLU, PICALM, and TNK1 Genotypes in Aging With and Without Alzheimer's Disease.

Mol Neurobiol 2018 May 19;55(5):4333-4344. Epub 2017 Jun 19.

Complex Structure of Geriatrics, Research Laboratory, Department of Medical Sciences, I.R.C.C.S. Casa Sollievo della Sofferenza, Viale Cappuccini 1, 71013, San Giovanni Rotondo, Foggia, Italy.

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May 2018

Midlife Metabolic Profile and the Risk of Late-Life Cognitive Decline.

J Alzheimers Dis 2017 ;59(1):121-130

Department of Clinical Research in Neurology, Unit of Neurodegenerative Disease, University of Bari "Aldo Moro" at "Pia Fondazione Card. G. Panico", Tricase, Lecce, Italy.

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April 2018

Information and Communication Technologies for the Activities of Daily Living in Older Patients with Dementia: A Systematic Review.

J Alzheimers Dis 2017 ;57(3):927-935

Department of Medical Sciences, Geriatric Unit and Laboratory of Gerontology and Geriatrics, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy.

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August 2017

Clinical and genetic analyses of familial and sporadic frontotemporal dementia patients in Southern Italy.

Alzheimers Dement 2017 Aug 3;13(8):858-869. Epub 2017 Mar 3.

Department of Clinical Research in Neurology, University of Bari, "Pia Fondazione Cardinale G. Panico", Lecce, Italy; Neurodegenerative Diseases Unit, Department of Basic Medical Science, Neuroscience and Sense Organs, University of Bari, Bari, Italy. Electronic address:

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August 2017

Emerging biomarkers and screening for cognitive frailty.

Aging Clin Exp Res 2017 Dec 4;29(6):1075-1086. Epub 2017 Mar 4.

Shanghai Key Laboratory of Clinical Geriatrics, Department of Geriatrics, Huadong Hospital, and Research Center of Aging and Medicine, Shanghai Institute of Geriatrics and Gerontology, Shanghai Medical College, Fudan University, Shanghai, 200040, China.

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December 2017

Reversible Cognitive Frailty, Dementia, and All-Cause Mortality. The Italian Longitudinal Study on Aging.

J Am Med Dir Assoc 2017 01;18(1):89.e1-89.e8

Gerontology-Geriatrics Research Laboratory, Istituto di Ricovero e Cura a Carattere Scientifico Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy; Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Department of Clinical Research in Neurology, University of Bari Aldo Moro, Pia Fondazione Cardinale G. Panico, Tricase, Lecce, Italy. Electronic address:

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January 2017

Looking Beyond the 5-HTTLPR Polymorphism: Genetic and Epigenetic Layers of Regulation Affecting the Serotonin Transporter Gene Expression.

Mol Neurobiol 2017 12 8;54(10):8386-8403. Epub 2016 Dec 8.

Institute of Translational Pharmacology (IFT), National Research Council (CNR), via Fosso del Cavaliere 100, 00133, Rome, Italy.

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December 2017

Phytochemicals in the Treatment of Alzheimer's Disease: A Systematic Review.

Curr Drug Targets 2017 ;18(13):1487-1498

Geriatric Unit & Laboratory of Gerontology and Geriatrics, Department of Medical Sciences, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy.

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June 2018

Bipolar Disorder and Frontotemporal Dementia: An Intriguing Association.

J Alzheimers Dis 2017 ;55(3):973-979

Department of Basic Medical Science, Neuroscience and Sense Organs, Neurodegenerative Disease Unit, University of Bari "Aldo Moro", Bari, Italy.

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February 2018

Pharmacogenetics of neurological and psychiatric diseases at older age: has the time come?

Expert Opin Drug Metab Toxicol 2017 Mar 20;13(3):259-277. Epub 2016 Oct 20.

c Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences , IRCCS Casa Sollievo della Sofferenza , San Giovanni Rotondo , Italy.

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March 2017

Emerging drugs to reduce abnormal β-amyloid protein in Alzheimer's disease patients.

Expert Opin Emerg Drugs 2016 Dec 6;21(4):377-391. Epub 2016 Oct 6.

a Unit of Neurodegenerative Disease, Department of Basic Medicine Sciences, Neuroscience, and Sense Organs , University of Bari 'Aldo Moro' , Bari , Italy.

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December 2016

Efficacy and Safety of Long-Term Administration of Tapentadol in Relieving Chronic Pancreatitis Pain.

Pain Med 2017 04;18(4):815-817

Division of GastroenterologyGeriatric Unit & Gerontology-Geriatrics Research LaboratoryDepartment of Anesthesiology, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy.

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April 2017

Tau-Centric Targets and Drugs in Clinical Development for the Treatment of Alzheimer's Disease.

Biomed Res Int 2016 26;2016:3245935. Epub 2016 Jun 26.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy; Department of Clinical Research in Neurology, University of Bari Aldo Moro, "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy.

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February 2017

Psychiatry meets pharmacogenetics for the treatment of revolving door patients with psychiatric disorders.

Expert Rev Neurother 2016 12 11;16(12):1357-1369. Epub 2016 Jul 11.

a Geriatric Unit and Geriatric Research Laboratory, Department of Medical Sciences , IRCCS Casa Sollievo della Sofferenza , Foggia , Italy.

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December 2016

Can a Positive Allosteric Modulation of GABAergic Receptors Improve Motor Symptoms in Patients with Parkinson's Disease? The Potential Role of Zolpidem in the Treatment of Parkinson's Disease.

Parkinsons Dis 2016 17;2016:2531812. Epub 2016 May 17.

Geriatric Unit and Laboratory of Gerontology and Geriatrics, Department of Medical Sciences, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, 71013 Foggia, Italy.

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June 2016

High doses of incobotulinumtoxinA for the treatment of post-stroke spasticity: are they safe and effective?

Expert Opin Drug Metab Toxicol 2016 Aug 17;12(8):843-6. Epub 2016 Jun 17.

c Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , University of Bari Aldo Moro , Bari , Italy.

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August 2016

Genetic Profile, Environmental Exposure, and Their Interaction in Parkinson's Disease.

Parkinsons Dis 2016 31;2016:6465793. Epub 2016 Jan 31.

Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, 71013 Foggia, Italy.

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March 2016

Delusions in Patients with Alzheimer's Disease: A Multidimensional Approach.

J Alzheimers Dis 2016 ;51(2):427-37

Geriatric Unit & Laboratory of Gerontology and Geriatrics, Department of Medical Sciences, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, Foggia, Italy.

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December 2016

Klotho Gene and Selective Serotonin Reuptake Inhibitors: Response to Treatment in Late-Life Major Depressive Disorder.

Mol Neurobiol 2017 03 3;54(2):1340-1351. Epub 2016 Feb 3.

Gerontology-Geriatric Research Laboratory, Department of Medical Sciences, I.R.C.C.S. "Casa Sollievo della Sofferenza", 71013 San Giovanni Rotondo, Foggia, Italy.

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March 2017

Tau-directed approaches for the treatment of Alzheimer's disease: focus on leuco-methylthioninium.

Expert Rev Neurother 2016 ;16(3):259-77

a Geriatric Unit & Laboratory of Gerontology and Geriatrics, Department of Medical Sciences , IRCCS 'Casa Sollievo della Sofferenza' , San Giovanni Rotondo , Foggia , Italy.

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December 2016

Tau aggregation inhibitors: the future of Alzheimer's pharmacotherapy?

Expert Opin Pharmacother 2016 15;17(4):457-61. Epub 2016 Feb 15.

a Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , University of Bari Aldo Moro , Bari , Italy.

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June 2016

Postural and Balance Disorders in Patients with Parkinson's Disease: A Prospective Open-Label Feasibility Study with Two Months of Action Observation Treatment.

Parkinsons Dis 2015 22;2015:902738. Epub 2015 Dec 22.

Geriatric Unit & Laboratory of Gerontology and Geriatrics, Department of Medical Sciences, IRCCS "Casa Sollievo della Sofferenza", San Giovanni Rotondo, 71013 Foggia, Italy; Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, 70124 Bari, Italy; Department of Clinical Research in Neurology, University of Bari Aldo Moro, "Pia Fondazione Cardinale G. Panico", Tricase, 73039 Lecce, Italy.

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January 2016

Role of the 5-HTTLPR and SNP Promoter Polymorphisms on Serotonin Transporter Gene Expression: a Closer Look at Genetic Architecture and In Vitro Functional Studies of Common and Uncommon Allelic Variants.

Mol Neurobiol 2016 10 13;53(8):5510-26. Epub 2015 Oct 13.

National Research Council (CNR), Institute of Translational Pharmacology (IFT), via Fosso del Cavaliere 100, 00133, Rome, Italy.

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October 2016

Targeting Cognitive Frailty: Clinical and Neurobiological Roadmap for a Single Complex Phenotype.

J Alzheimers Dis 2015 ;47(4):793-813

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro, Bari, Italy.

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July 2016

Progresses in treating agitation: a major clinical challenge in Alzheimer's disease.

Expert Opin Pharmacother 2015 21;16(17):2581-8. Epub 2015 Sep 21.

a 1 University of Bari Aldo Moro, Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , Bari, Italy ,

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June 2016

Age-related hearing impairment and frailty in Alzheimer's disease: interconnected associations and mechanisms.

Front Aging Neurosci 2015 9;7:113. Epub 2015 Jun 9.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro Bari, Italy ; Department of Clinical Research in Neurology, University of Bari Aldo Moro, "Pia Fondazione Cardinale G. Panico" Tricase, Italy.

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June 2015

Measuring pharmacogenetics in special groups: geriatrics.

Expert Opin Drug Metab Toxicol 2015 Jul 19;11(7):1073-88. Epub 2015 May 19.

IRCCS Casa Sollievo della Sofferenza, Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences , San Giovanni Rotondo, Foggia , Italy

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July 2015

Role of CYP2D6 Polymorphisms in the Outcome of Postoperative Pain Treatment.

Pain Med 2015 Oct 19;16(10):2012-23. Epub 2015 May 19.

Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy.

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October 2015

Role of the serotonin transporter gene locus in the response to SSRI treatment of major depressive disorder in late life.

J Psychopharmacol 2015 May 31;29(5):623-33. Epub 2015 Mar 31.

Department of Medical Sciences, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy Geriatrics Unit, San Antonio Hospital, Padova, Italy.

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May 2015

Cognitive Frailty: A Systematic Review of Epidemiological and Neurobiological Evidence of an Age-Related Clinical Condition.

Rejuvenation Res 2015 Oct 20;18(5):389-412. Epub 2015 Aug 20.

3 Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro , Bari, Italy .

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October 2015

FOXO1 locus and acetylcholinesterase inhibitors in elderly patients with Alzheimer's disease.

Clin Interv Aging 2014 21;9:1783-91. Epub 2014 Oct 21.

Gerontology and Geriatrics Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy ; Geriatrics Unit, Azienda ULSS 16 Padova, San Antonio Hospital, Padova, Italy.

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April 2015

Nutrition, frailty, and Alzheimer's disease.

Front Aging Neurosci 2014 26;6:221. Epub 2014 Aug 26.

Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs, University of Bari Aldo Moro Bari, Italy ; Department of Clinical Research in Neurology, University of Bari Aldo Moro, "Pia Fondazione Cardinale G. Panico" Lecce, Italy.

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September 2014

Functional genetic variation in the serotonin 5-HTTLPR modulates brain damage in frontotemporal dementia.

Neurobiol Aging 2015 Jan 15;36(1):446-51. Epub 2014 Jul 15.

Centre for Ageing Brain and Neurodegenerative Disorders, Neurology Unit, University of Brescia, Brescia, Italy. Electronic address:

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January 2015

Frailty, disability and physical exercise in the aging process and in chronic kidney disease.

Kidney Blood Press Res 2014 29;39(2-3):164-8. Epub 2014 Jul 29.

Geriatric Unit and Gerontology-Geriatrics Research Laboratory, Department of Medical Sciences, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy.

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May 2015

Efficacy and safety studies of gantenerumab in patients with Alzheimer's disease.

Expert Rev Neurother 2014 Sep 1;14(9):973-86. Epub 2014 Aug 1.

Department of Basic Medicine, Neuroscience, and Sense Organs, Neurodegenerative Disease Unit, University of Bari Aldo Moro, Bari, Italy.

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September 2014

Systemic oxidative stress and conversion to dementia of elderly patients with mild cognitive impairment.

Biomed Res Int 2014 12;2014:309507. Epub 2014 Jan 12.

Section of Internal Medicine, Gerontology, and Clinical Nutrition, Department of Medical Science, University of Ferrara, Via Savonarola 9, 44100 Ferrara, Italy.

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December 2014

Oxidative balance, homocysteine, and uric acid levels in older patients with Late Onset Alzheimer's Disease or Vascular Dementia.

J Neurol Sci 2014 Feb 4;337(1-2):156-61. Epub 2013 Dec 4.

Department of Medical Science, Section of Internal Medicine, Gerontology, and Clinical Nutrition, University of Ferrara, 44100 Ferrara, Italy.

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February 2014

The serotonin transporter gene locus in late-life major depressive disorder.

Am J Geriatr Psychiatry 2013 Jan 2;21(1):67-77. Epub 2013 Jan 2.

Geriatric Unit & Gerontology-Geriatric Research Laboratory, Department of Medical Sciences, Institute of Care and Scientific Research Casa Sollievo della Sofferenza, San Giovanni Rotondo, Foggia, Italy.

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January 2013

[Forkhead-box-O1 locus and metabolic markers in the elderly: an association study].

Rev Esp Geriatr Gerontol 2012 Nov-Dec;47(6):254-8. Epub 2012 Oct 8.

Unidad Geriátrica y Laboratorio de Investigación de Gerontología y Geriatría, Departamento de Ciencias Médicas, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italia.

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December 2013