David Wolk

David Wolk

UNVERIFIED PROFILE

Are you David Wolk?   Register this Author

Register author
David Wolk

David Wolk

Publications by authors named "David Wolk"

Are you David Wolk?   Register this Author

100Publications

2214Reads

37Profile Views

In vivo measures of tau burden are associated with atrophy in early Braak stage medial temporal lobe regions in amyloid-negative individuals.

Alzheimers Dement 2019 Sep 5. Epub 2019 Sep 5.

Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA; Penn Memory Center, University of Pennsylvania, Philadelphia, PA, USA; Penn Alzheimer's Disease Core Center, University of Pennsylvania, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2019.05.009DOI Listing
September 2019

Automated segmentation of medial temporal lobe subregions on in vivo T1-weighted MRI in early stages of Alzheimer's disease.

Hum Brain Mapp 2019 Aug 29;40(12):3431-3451. Epub 2019 Apr 29.

Penn Image Computing and Science Laboratory (PICSL), Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.24607DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6697377PMC
August 2019

A deep learning model for early prediction of Alzheimer's disease dementia based on hippocampal magnetic resonance imaging data.

Alzheimers Dement 2019 Aug 11;15(8):1059-1070. Epub 2019 Jun 11.

Section for Biomedical Image Analysis (SBIA), Center for Biomedical Image Computing and Analytics (CBICA), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2019.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719787PMC
August 2019

Disease Course Varies According to Age and Symptom Length in Alzheimer's Disease.

J Alzheimers Dis 2018 ;64(2):631-642

Department of Medical Statistics, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-170841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6207933PMC
July 2019

Empiric Methods to Account for Pre-analytical Variability in Digital Histopathology in Frontotemporal Lobar Degeneration.

Front Neurosci 2019 3;13:682. Epub 2019 Jul 3.

Penn Digital Neuropathology Laboratory, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fnins.2019.00682DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616086PMC
July 2019

Fractionating the Rey Auditory Verbal Learning Test: Distinct roles of large-scale cortical networks in prodromal Alzheimer's disease.

Neuropsychologia 2019 Jun 28;129:83-92. Epub 2019 Mar 28.

Department of Neurology, Frontotemporal Disorders Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuropsychologia.2019.03.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6571167PMC
June 2019

Putting the New Alzheimer Disease Amyloid, Tau, Neurodegeneration (AT[N]) Diagnostic System to the Test.

JAMA 2019 06;321(23):2289-2291

Frontotemporal Disorders Unit & Alzheimer's Disease Research Center, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jama.2019.7534DOI Listing
June 2019

Characterizing a perfusion-based periventricular small vessel region of interest.

Neuroimage Clin 2019 12;23:101897. Epub 2019 Jun 12.

Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA; Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2019.101897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6595083PMC
June 2019

Divergent patterns of TDP-43 and tau pathologies in primary progressive aphasia.

Ann Neurol 2019 May 28;85(5):630-643. Epub 2019 Mar 28.

Penn Frontotemporal Degeneration Center, Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ana.25465DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538935PMC
May 2019

Early Tau Burden Correlates with Higher Rate of Atrophy in Transentorhinal Cortex.

J Alzheimers Dis 2018 ;62(1):85-92

Penn Memory Center, University of Pennsylvania, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-170945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880816PMC
March 2019

Older Adult Normative Data for the Sniffin' Sticks Odor Identification Test.

Arch Clin Neuropsychol 2019 Mar;34(2):254-258

Alzheimer's Disease Center, Department of Neurology, Perelman School of Medicine, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/arclin/acy021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487533PMC
March 2019

Elevated CSF GAP-43 is Alzheimer's disease specific and associated with tau and amyloid pathology.

Alzheimers Dement 2019 01 12;15(1):55-64. Epub 2018 Oct 12.

Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Mölndal, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, Mölndal, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2018.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333489PMC
January 2019

Prevalence of amyloid-β pathology in distinct variants of primary progressive aphasia.

Ann Neurol 2018 11;84(5):729-740

Alzheimer center Amsterdam, Amsterdam UMC, Amsterdam Neuroscience, VU University, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ana.25333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354051PMC
November 2018

White matter lesions: Spatial heterogeneity, links to risk factors, cognition, genetics, and atrophy.

Neurology 2018 09 3;91(10):e964-e975. Epub 2018 Aug 3.

From the Center for Biomedical Image Computing and Analytics (M.H., A.S., G.E., N.R.B., J.D., C.D.), Department of Neurology and Penn Memory Center (M.H., D.A.W.), and Department of Biostatistics and Epidemiology (H.S.), University of Pennsylvania, Philadelphia; Department of Psychiatry (M.H., D.J., H.J.G.), Institute for Community Medicine (M.H., H.V., W.H.), and Department of Neurology (U.S.), University of Greifswald, Germany; Department of Neurology (J.B.T.), Houston Methodist Hospital, TX; German Center for Neurodegenerative Diseases (W.H., H.J.G.), Rostock/Greifswald, Germany; and Laboratory of Behavioral Neuroscience (S.M.R.), National Institute on Aging, Baltimore, MD.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000006116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6139818PMC
September 2018

Characterizing Anatomical Variability And Alzheimer's Disease Related Cortical Thinning in the Medial Temporal Lobe Using Graph-Based Groupwise Registration And Point Set Geodesic Shooting.

Shape Med Imaging (2018) 2018 Sep 23;11167:28-37. Epub 2018 Nov 23.

Penn Image Computing and Science Laboratory (PICSL), Department of Radiology, University of Pennsylvania, Philadelphia, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-030-04747-4_3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469499PMC
September 2018

Cerebrospinal fluid α-synuclein contributes to the differential diagnosis of Alzheimer's disease.

Alzheimers Dement 2018 08 28;14(8):1052-1062. Epub 2018 Mar 28.

Department of Pathology, University of Washington School of Medicine, Seattle, WA, USA; Department of Pathology, Peking University Health Science Centre and Third Hospital, Beijing, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2018.02.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6097943PMC
August 2018

Alzheimer's genetic risk is reduced in primary age-related tauopathy: a potential model of resistance?

Ann Clin Transl Neurol 2018 Aug 19;5(8):927-934. Epub 2018 Jun 19.

Department of Neurology Perelman School of Medicine University of Pennsylvania Philadelphia Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/acn3.581DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093846PMC
August 2018

The technical reliability and biotemporal stability of cerebrospinal fluid biomarkers for profiling multiple pathophysiologies in Alzheimer's disease.

PLoS One 2018 5;13(3):e0193707. Epub 2018 Mar 5.

MGH Institute for Neurodegenerative Disease, Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193707PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837100PMC
July 2018

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.

Authors:
Niklas Mattsson Colin Groot Willemijn J Jansen Susan M Landau Victor L Villemagne Sebastiaan Engelborghs Mark M Mintun Alberto Lleo José Luis Molinuevo William J Jagust Giovanni B Frisoni Adrian Ivanoiu Gaël Chételat Catarina Resende de Oliveira Karen M Rodrigue Johannes Kornhuber Anders Wallin Aleksandra Klimkowicz-Mrowiec Ramesh Kandimalla Julius Popp Pauline P Aalten Dag Aarsland Daniel Alcolea Ina S Almdahl Inês Baldeiras Mark A van Buchem Enrica Cavedo Kewei Chen Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Kiran Dip Gill Olymbia Gkatzima Timo Grimmer Harald Hampel Sanna-Kaisa Herukka Peter Johannsen Koen van Laere Mony J de Leon Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Barbara Mroczko Arto Nordlund Sudesh Prabhakar Oliver Peters Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Frans R J Verhey Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Rik Vandenberghe David J Brooks Tormod Fladby Christopher C Rowe Alexander Drzezga Marcel M Verbeek Marie Sarazin David A Wolk Adam S Fleisher William E Klunk Duk L Na Pascual Sánchez-Juan Dong Young Lee Agneta Nordberg Magda Tsolaki Vincent Camus Juha O Rinne Anne M Fagan Henrik Zetterberg Kaj Blennow Gil D Rabinovici Oskar Hansson Bart N M van Berckel Wiesje M van der Flier Philip Scheltens Pieter Jelle Visser Rik Ossenkoppele

Alzheimers Dement 2018 07 28;14(7):913-924. Epub 2018 Mar 28.

Clinical Memory Research Unit, Clinical Sciences Malmö, Lund University, Lund, Sweden; Department of Neurology and Alzheimer Center, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands; Department of Radiology and Nuclear Medicine, VU University Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2018.02.009DOI Listing
July 2018

Longitudinal and cross-sectional structural magnetic resonance imaging correlates of AV-1451 uptake.

Neurobiol Aging 2018 06 9;66:49-58. Epub 2018 Feb 9.

Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA; Penn Memory Center, University of Pennsylvania, Philadelphia, PA, USA; Penn Alzheimer's Disease Core Center, University of Pennsylvania, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2018.01.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924615PMC
June 2018

Quantitative assessment of finger tapping characteristics in mild cognitive impairment, Alzheimer's disease, and Parkinson's disease.

J Neurol 2018 Jun 4;265(6):1365-1375. Epub 2018 Apr 4.

Neuropsychiatry Section, Department of Psychiatry, 10th Floor, Gates Building, Hospital of the University of Pennsylvania, University of Pennsylvania Perelman School of Medicine, 3400 Spruce Street, Philadelphia, PA, 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00415-018-8841-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992087PMC
June 2018

Neocortical origin and progression of gray matter atrophy in nonamnestic Alzheimer's disease.

Neurobiol Aging 2018 03 21;63:75-87. Epub 2017 Nov 21.

Penn Frontotemporal Degeneration Center, University of Pennsylvania, Philadelphia, PA, USA; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2017.11.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801003PMC
March 2018

CSF tau and β-amyloid predict cerebral synucleinopathy in autopsied Lewy body disorders.

Neurology 2018 03 21;90(12):e1038-e1046. Epub 2018 Feb 21.

From Penn Frontotemporal Degeneration Center (D.J.I., N.N., C.T.M., M.G.), Alzheimer's Disease Core Center (D.A.W., J.Q.T.), Department of Neurology (D.J.I., D.C., R.S.A., C.T.M., D.A.W., D.W., A.C.-P., M.S., A.S., H.I.H., M.G.), Penn Morris K. Udall Parkinson's Disease Research Center of Excellence (D.J.I., R.S.A., C.T.M., D.W., A.C.-P., J.E.D., M.G., J.Q.T.), Center for Neurodegenerative Disease Research (L.M.S., J.Q.T.), Translational Neuropathology Research Laboratory (E.B.L.), Department of Pathology and Laboratory Medicine (E.B.L., L.M.S., J.Q.T.), and Department of Biostatistics and Epidemiology Perelman School of Medicine (S.X.X.), University of Pennsylvania; and Parkinson's Disease Research, Education and Clinical Center (D.W., J.E.D.), Michael J. Crescenz VA Medical Center, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
Publisher Site
http://dx.doi.org/10.1212/WNL.0000000000005166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874449PMC
March 2018

Tau PET imaging predicts cognition in atypical variants of Alzheimer's disease.

Hum Brain Mapp 2018 02 6;39(2):691-708. Epub 2017 Nov 6.

Penn Frontotemporal Degeneration Center, Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, 19104.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.23874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5764792PMC
February 2018

Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.

Authors:
Willemijn J Jansen Rik Ossenkoppele Betty M Tijms Anne M Fagan Oskar Hansson William E Klunk Wiesje M van der Flier Victor L Villemagne Giovanni B Frisoni Adam S Fleisher Alberto Lleó Mark A Mintun Anders Wallin Sebastiaan Engelborghs Duk L Na Gäel Chételat José Luis Molinuevo Susan M Landau Niklas Mattsson Johannes Kornhuber Osama Sabri Christopher C Rowe Lucilla Parnetti Julius Popp Tormod Fladby William J Jagust Pauline Aalten Dong Young Lee Rik Vandenberghe Catarina Resende de Oliveira Elisabeth Kapaki Lutz Froelich Adrian Ivanoiu Tomasz Gabryelewicz Marcel M Verbeek Páscual Sanchez-Juan Helmut Hildebrandt Vincent Camus Marzena Zboch David J Brooks Alexander Drzezga Juha O Rinne Andrew Newberg Alexandre de Mendonça Marie Sarazin Gil D Rabinovici Karine Madsen Milica G Kramberger Agneta Nordberg Vincent Mok Barbara Mroczko David A Wolk Philipp T Meyer Magda Tsolaki Philip Scheltens Frans R J Verhey Pieter Jelle Visser Dag Aarsland Daniel Alcolea Myriam Alexander Ina S Almdahl Steven E Arnold Inês Baldeiras Henryk Barthel Bart N M van Berckel Kaj Blennow Mark A van Buchem Enrica Cavedo Kewei Chen Elena Chipi Ann D Cohen Stefan Förster Juan Fortea Kristian S Frederiksen Yvonne Freund-Levi Olymbia Gkatzima Mark Forrest Gordon Timo Grimmer Harald Hampel Lucrezia Hausner Sabine Hellwig Sanna-Kaisa Herukka Peter Johannsen Aleksandra Klimkowicz-Mrowiec Sebastian Köhler Norman Koglin Koen van Laere Mony de Leon Viviana Lisetti Wolfgang Maier Jan Marcusson Olga Meulenbroek Hanne M Møllergård John C Morris Arto Nordlund Gerald P Novak George P Paraskevas Gayan Perera Oliver Peters Inez H G B Ramakers Lorena Rami Eloy Rodríguez-Rodríguez Catherine M Roe Uros Rot Eckart Rüther Isabel Santana Johannes Schröder Sang W Seo Hilkka Soininen Luiza Spiru Erik Stomrud Hanne Struyfs Charlotte E Teunissen Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Åsa K Wallin Jens Wiltfang Henrik Zetterberg

JAMA Psychiatry 2018 01;75(1):84-95

Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jamapsychiatry.2017.3391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786156PMC
January 2018

Approach to atypical Alzheimer's disease and case studies of the major subtypes.

CNS Spectr 2017 12 15;22(6):439-449. Epub 2017 Feb 15.

5Department of Neurology,University of Pennsylvania,Philadelphia,Pennsylvania,USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1017/S109285291600047XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5557706PMC
December 2017

Effects of the Insulin Sensitizer Metformin in Alzheimer Disease: Pilot Data From a Randomized Placebo-controlled Crossover Study.

Alzheimer Dis Assoc Disord 2017 Apr-Jun;31(2):107-113

*Penn Memory Center Departments of †Biostatistics and Epidemiology ‡Medicine §Radiology ∥Neurology, University of Pennsylvania, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/WAD.0000000000000202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476214PMC
December 2017

A brain stress test: Cerebral perfusion during memory encoding in mild cognitive impairment.

Neuroimage Clin 2016 2;11:388-397. Epub 2016 Mar 2.

Penn Memory Center, University of Pennsylvania, Philadelphia, PA, USA; Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2016.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821452PMC
October 2017

Comparison of PASL, PCASL, and background-suppressed 3D PCASL in mild cognitive impairment.

Hum Brain Mapp 2017 10 24;38(10):5260-5273. Epub 2017 Jul 24.

Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hbm.23732
Publisher Site
http://dx.doi.org/10.1002/hbm.23732DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5593784PMC
October 2017

Whole-brain background-suppressed pCASL MRI with 1D-accelerated 3D RARE Stack-Of-Spirals readout.

PLoS One 2017 24;12(8):e0183762. Epub 2017 Aug 24.

Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0183762PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570334PMC
October 2017

Cognitive decline associated with pathological burden in primary age-related tauopathy.

Alzheimers Dement 2017 Sep 16;13(9):1048-1053. Epub 2017 Mar 16.

Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2017.01.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585025PMC
September 2017

Effects of cognitive reserve depend on executive and semantic demands of the task.

J Neurol Neurosurg Psychiatry 2017 09 19;88(9):794-802. Epub 2017 Jun 19.

Frontotemporal Dementia Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2017-315719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963955PMC
September 2017

Bridging cognitive screening tests in neurologic disorders: A crosswalk between the short Montreal Cognitive Assessment and Mini-Mental State Examination.

Alzheimers Dement 2017 Aug 24;13(8):947-952. Epub 2017 Feb 24.

Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Alzheimer's Disease Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2017.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554086PMC
August 2017

Ante mortem cerebrospinal fluid tau levels correlate with postmortem tau pathology in frontotemporal lobar degeneration.

Ann Neurol 2017 Aug 19;82(2):247-258. Epub 2017 Aug 19.

Frontotemporal Degeneration Center, Department of Neurology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ana.24996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776747PMC
August 2017

Structural Correlation-based Outlier Rejection (SCORE) algorithm for arterial spin labeling time series.

J Magn Reson Imaging 2017 06 29;45(6):1786-1797. Epub 2016 Aug 29.

Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jmri.25436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332532PMC
June 2017

Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia.

Neurology 2017 Jun 17;88(24):2276-2284. Epub 2017 May 17.

From the Department of Neurology (L.A.A.G.), University Medical Center Groningen, University of Groningen, the Netherlands; Penn Frontotemporal Degeneration Center, Department of Neurology (L.A.A.G., D.J.I., C.T.M., S.A., K.R., M.G.), Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine (D.J.I., V.M.V.D., J.Q.T.), Alzheimer's Disease Center (D.A.W.), Department of Neurology, and Translational Pathology Laboratory, Perelman School of Medicine (E.B.L.), University of Pennsylvania, Philadelphia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1212/WNL.0000000000004034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5567322PMC
June 2017

A quantitative meta-analysis of olfactory dysfunction in mild cognitive impairment.

J Neurol Neurosurg Psychiatry 2017 Mar 30;88(3):226-232. Epub 2016 Dec 30.

Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2016-314638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350628PMC
March 2017

Multi-template analysis of human perirhinal cortex in brain MRI: Explicitly accounting for anatomical variability.

Neuroimage 2017 01 1;144(Pt A):183-202. Epub 2016 Oct 1.

Penn Image Computing and Science Laboratory (PICSL), Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA; Department of Radiology, University of Pennsylvania, Philadelphia, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2016.09.070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5183532PMC
January 2017

Medial temporal lobe subregional morphometry using high resolution MRI in Alzheimer's disease.

Neurobiol Aging 2017 01 30;49:204-213. Epub 2016 Sep 30.

Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2016.09.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154888PMC
January 2017

Neural signatures of experience-based improvements in deterministic decision-making.

Behav Brain Res 2016 12 11;315:51-65. Epub 2016 Aug 11.

University of Pittsburgh, Pittsburgh, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbr.2016.08.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017924PMC
December 2016

Multimodal evaluation demonstrates in vivo F-AV-1451 uptake in autopsy-confirmed corticobasal degeneration.

Acta Neuropathol 2016 12 4;132(6):935-937. Epub 2016 Nov 4.

Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, 3 West Gates, Philadelphia, PA, 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00401-016-1640-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154298PMC
December 2016

Introduction to special edition, "State of the Field: Advances in Neuroimaging from the 2016 Alzheimer's Imaging Consortium".

Alzheimers Dement (Amst) 2016 21;5:67-69. Epub 2016 Dec 21.

Department of Neurology, Indiana University School of Medicine, Indianapolis, IN, USA; Department of Radiology and Imaging Sciences, Center for Neuroimaging, Indiana University, School of Medicine, Indianapolis, IN, USA; Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dadm.2016.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5198873PMC
December 2016

Alzheimer's disease: The influence of age on clinical heterogeneity through the human brain connectome.

Alzheimers Dement (Amst) 2017 22;6:122-135. Epub 2016 Dec 22.

Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dadm.2016.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318292PMC
December 2016

Presence of cerebral amyloid modulates phenotype and pattern of neurodegeneration in early Parkinson's disease.

J Neurol Neurosurg Psychiatry 2016 10 9;87(10):1112-22. Epub 2016 Jun 9.

Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/jnnp-2015-312690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5154297PMC
October 2016

Accounting for the Confound of Meninges in Segmenting Entorhinal and Perirhinal Cortices in T1-Weighted MRI.

Med Image Comput Comput Assist Interv 2016 Oct 2;9901:564-571. Epub 2016 Oct 2.

Penn Image Computing and Science Laboratory (PICSL), Department of Radiology, University of Pennsylvania, Philadelphia, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-3-319-46723-8_65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526195PMC
October 2016

Multimodal imaging evidence of pathology-mediated disease distribution in corticobasal syndrome.

Neurology 2016 Sep 19;87(12):1227-34. Epub 2016 Aug 19.

From the Department of Neurology (C.T.M., C.B., R.G.G., J.W., K.F., K.R., D.A.W., D.J.I., M.G.) and Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine (J.B.T., L.S., D.J.I., E.B.L., J.Q.T.), Perelman School of Medicine, University of Pennsylvania, Philadelphia.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035978PMC
http://dx.doi.org/10.1212/WNL.0000000000003119DOI Listing
September 2016

Neuropsychological Testing Predicts Cerebrospinal Fluid Amyloid-β in Mild Cognitive Impairment.

J Alzheimers Dis 2015 ;46(4):901-12

Department of Neurology, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3233/JAD-142943DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4699841PMC
June 2016

Suspected non-AD pathology in mild cognitive impairment.

Neurobiol Aging 2015 Dec 7;36(12):3152-3162. Epub 2015 Sep 7.

Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2015.08.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4641774PMC
December 2015

Alzheimer's disease first symptoms are age dependent: Evidence from the NACC dataset.

Alzheimers Dement 2015 Nov 24;11(11):1349-57. Epub 2015 Apr 24.

Department of Neurology, Alzheimer Center, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands; Department of Epidemiology & Biostatistics, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jalz.2014.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619185PMC
November 2015

P50: A candidate ERP biomarker of prodromal Alzheimer's disease.

Brain Res 2015 Oct 6;1624:390-397. Epub 2015 Aug 6.

Department of Psychology, Drexel University, Stratton Hall, 3141 Chestnut Street, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://users.rowan.edu/~polikar/research/publications/br2015
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S000689931500599
Publisher Site
http://dx.doi.org/10.1016/j.brainres.2015.07.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4630129PMC
October 2015

Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.

Authors:
Willemijn J Jansen Rik Ossenkoppele Dirk L Knol Betty M Tijms Philip Scheltens Frans R J Verhey Pieter Jelle Visser Pauline Aalten Dag Aarsland Daniel Alcolea Myriam Alexander Ina S Almdahl Steven E Arnold Inês Baldeiras Henryk Barthel Bart N M van Berckel Kristen Bibeau Kaj Blennow David J Brooks Mark A van Buchem Vincent Camus Enrica Cavedo Kewei Chen Gael Chetelat Ann D Cohen Alexander Drzezga Sebastiaan Engelborghs Anne M Fagan Tormod Fladby Adam S Fleisher Wiesje M van der Flier Lisa Ford Stefan Förster Juan Fortea Nadia Foskett Kristian S Frederiksen Yvonne Freund-Levi Giovanni B Frisoni Lutz Froelich Tomasz Gabryelewicz Kiran Dip Gill Olymbia Gkatzima Estrella Gómez-Tortosa Mark Forrest Gordon Timo Grimmer Harald Hampel Lucrezia Hausner Sabine Hellwig Sanna-Kaisa Herukka Helmut Hildebrandt Lianna Ishihara Adrian Ivanoiu William J Jagust Peter Johannsen Ramesh Kandimalla Elisabeth Kapaki Aleksandra Klimkowicz-Mrowiec William E Klunk Sebastian Köhler Norman Koglin Johannes Kornhuber Milica G Kramberger Koen Van Laere Susan M Landau Dong Young Lee Mony de Leon Viviana Lisetti Alberto Lleó Karine Madsen Wolfgang Maier Jan Marcusson Niklas Mattsson Alexandre de Mendonça Olga Meulenbroek Philipp T Meyer Mark A Mintun Vincent Mok José Luis Molinuevo Hanne M Møllergård John C Morris Barbara Mroczko Stefan Van der Mussele Duk L Na Andrew Newberg Agneta Nordberg Arto Nordlund Gerald P Novak George P Paraskevas Lucilla Parnetti Gayan Perera Oliver Peters Julius Popp Sudesh Prabhakar Gil D Rabinovici Inez H G B Ramakers Lorena Rami Catarina Resende de Oliveira Juha O Rinne Karen M Rodrigue Eloy Rodríguez-Rodríguez Catherine M Roe Uros Rot Christopher C Rowe Eckart Rüther Osama Sabri Páscual Sanchez-Juan Isabel Santana Marie Sarazin Johannes Schröder Christin Schütte Sang W Seo Femke Soetewey Hilkka Soininen Luiza Spiru Hanne Struyfs Charlotte E Teunissen Magda Tsolaki Rik Vandenberghe Marcel M Verbeek Victor L Villemagne Stephanie J B Vos Linda J C van Waalwijk van Doorn Gunhild Waldemar Anders Wallin Åsa K Wallin Jens Wiltfang David A Wolk Marzena Zboch Henrik Zetterberg

JAMA 2015 May;313(19):1924-38

Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg, Mölndal, Sweden87UCL Institute of Neurology, Queen Square, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1001/jama.2015.4668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486209PMC
May 2015

Automated volumetry and regional thickness analysis of hippocampal subfields and medial temporal cortical structures in mild cognitive impairment.

Hum Brain Mapp 2015 Jan 2;36(1):258-87. Epub 2014 Sep 2.

Penn Image Computing and Science Laboratory, Department of Radiology, University of Pennsylvania, Philadelphia, PA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hbm.22627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313574PMC
January 2015

Anterior and posterior MTL networks in aging and MCI.

Neurobiol Aging 2015 Jan 28;36 Suppl 1:S141-50, S150.e1. Epub 2014 Sep 28.

Department of Neurology, University of Pennsylvania, Pennsylvania, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neurobiolaging.2014.03.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342050PMC
January 2015

Multimodality imaging of Alzheimer disease and other neurodegenerative dementias.

J Nucl Med 2014 Dec 20;55(12):2003-11. Epub 2014 Nov 20.

Hospital of the University of Pennsylvania, University of Pennsylvania, Philadelphia, Pennsylvania.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2967/jnumed.114.141416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702268PMC
December 2014

Subject-specific functional parcellation via prior based eigenanatomy.

Neuroimage 2014 Oct 20;99:14-27. Epub 2014 May 20.

Penn Image Computing and Science Laboratory (PICSL), Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuroimage.2014.05.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382016PMC
October 2014

CSF Apo-E levels associate with cognitive decline and MRI changes.

Acta Neuropathol 2014 May 3;127(5):621-32. Epub 2014 Jan 3.

Department of Pathology and Laboratory Medicine, Institute on Aging, Center for Neurodegenerative Disease Research, University of Pennsylvania School of Medicine, HUP, Maloney 3rd, 36th and Spruce Streets, Philadelphia, PA, 19104-4283, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00401-013-1236-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988233PMC
May 2014

Neuronal injury biomarkers and prognosis in ADNI subjects with normal cognition.

Acta Neuropathol Commun 2014 Mar 6;2:26. Epub 2014 Mar 6.

Department of Pathology & Laboratory Medicine, Institute on Aging, Center for Neurodegenerative Disease Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/2051-5960-2-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4008258PMC
March 2014

Subjective memory complaints, cognitive performance, and psychological factors in healthy older adults.

Am J Alzheimers Dis Other Demen 2013 Dec;28(8):776-83

1Department of Psychiatry, Crozer Chester Medical Center, One Medical Center Boulevard, Upland, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1533317513504817DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4617766PMC
December 2013

Recognition memory in amnestic-mild cognitive impairment: insights from event-related potentials.

Front Aging Neurosci 2013 11;5:89. Epub 2013 Dec 11.

Department of Neurology, University of Pennsylvania, Philadelphia PA, USA ; Penn Memory Center, University of Pennsylvania, Philadelphia PA, USA ; Department of Psychiatry, University of Pennsylvania, Philadelphia PA, USA.

View Article

Download full-text PDF

Source
http://journal.frontiersin.org/article/10.3389/fnagi.2013.00
Publisher Site
http://dx.doi.org/10.3389/fnagi.2013.00089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858817PMC
December 2013

Arterial spin labeled MRI in prodromal Alzheimer's disease: A multi-site study.

Neuroimage Clin 2013 30;2:630-6. Epub 2013 Apr 30.

Department of Radiology, University of Pennsylvania, Philadelphia, PA, USA ; Center for Functional Neuroimaging, University of Pennsylvania, Philadelphia, PA, USA ; Penn Memory Center, University of Pennsylvania, Philadelphia, PA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.nicl.2013.04.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777751PMC
November 2013