David Wendler

David Wendler

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David Wendler

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Issues and Challenges Associated with Data-Sharing in Low- and Middle-Income Countries: Perspectives of Researchers in Thailand.

Am J Trop Med Hyg 2020 May 11. Epub 2020 May 11.

Department of Bioethics, National Institutes of Health Clinical Center, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.4269/ajtmh.19-0651DOI Listing
May 2020

Conducting human challenge studies in LMICs: A survey of researchers and ethics committee members in Thailand.

PLoS One 2019 10;14(10):e0223619. Epub 2019 Oct 10.

Department of Bioethics, National Institutes of Health Clinical Center, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0223619PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6786649PMC
March 2020

The Permissibility of Deception in Riskier Research.

Authors:
David Wendler

Ethics Hum Res 2020 Mar;42(2):34-40

Head of the section on research ethics at the National Institutes of Health (NIH) Clinical Center.

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http://dx.doi.org/10.1002/eahr.500046DOI Listing
March 2020

Commentary: Should the Belmont Report Be Extended to Animal Research.

Camb Q Healthc Ethics 2020 Jan;29(1):58-66

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http://dx.doi.org/10.1017/S0963180119000781DOI Listing
January 2020

Ethical issues in denial of church wedding based on couple's hemoglobin genotype in Enugu, south eastern Nigeria.

BMC Med Ethics 2019 05 29;20(1):37. Epub 2019 May 29.

Department of Bioethics, Clinical Center, National Institutes of Health, Bethesda, MD, 20892-1156, USA.

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http://dx.doi.org/10.1186/s12910-019-0376-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542068PMC
May 2019

The Potential Benefits of Research May Justify Certain Research Risks.

Pediatrics 2019 03 20;143(3). Epub 2019 Feb 20.

Department of Pediatrics, Children's Mercy Hospital, Kansas City, Missouri

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http://dx.doi.org/10.1542/peds.2018-1703DOI Listing
March 2019

The Value in Doing Something.

Authors:
David Wendler

Crit Care Med 2019 02;47(2):149-151

Department of Bioethics, NIH Clinical Center, Bethesda, MD.

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http://dx.doi.org/10.1097/CCM.0000000000003503DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336515PMC
February 2019

Understanding preferences regarding consent for pragmatic trials in acute care.

Clin Trials 2018 12 3;15(6):567-578. Epub 2018 Oct 3.

2 Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA, USA.

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http://journals.sagepub.com/doi/10.1177/1740774518801007
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http://dx.doi.org/10.1177/1740774518801007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218277PMC
December 2018

Locating the Source(s) of the Social Value Requirement(s).

Authors:
David Wendler

Hastings Cent Rep 2018 11;48(6):33-35

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http://dx.doi.org/10.1002/hast.935DOI Listing
November 2018

Reconsidering the Need for Reconsent at 18.

Pediatrics 2018 08 6;142(2). Epub 2018 Jul 6.

Department of Bioethics, National Institutes of Health, Bethesda, Maryland; and.

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http://dx.doi.org/10.1542/peds.2017-1202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317640PMC
August 2018

Is it important to disclose how treatments are selected in clinical research and clinical care?

AJOB Empir Bioeth 2017 Jul-Sep;8(3):170-177. Epub 2017 Apr 3.

b Department of Bioethics , NIH Clinical Center.

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http://dx.doi.org/10.1080/23294515.2017.1314392DOI Listing
June 2018

When Research Regulations and Ethics Conflict.

Am J Bioeth 2018 04;18(4):96-97

a National Institutes of Health.

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http://dx.doi.org/10.1080/15265161.2018.1431706DOI Listing
April 2018

The Ethics of Research in Lower Income Countries: Double Standards Are Not the Problem.

Authors:
David S Wendler

J Clin Ethics 2017 ;28(3):239-246

Section on Research Ethics, Department of Bioethics, National Institutes of Health Clinical Center, Bethesda, Maryland USA.

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March 2018

Innovative approaches to informed consent for randomized clinical trials: Identifying the ethical challenges.

Authors:
David Wendler

Clin Trials 2018 02 17;15(1):17-20. Epub 2017 Dec 17.

Department of Bioethics, Clinical Center, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1177/1740774517746621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799024PMC
February 2018

Patients' and Parents' Needs, Attitudes, and Perceptions About Early Palliative Care Integration in Pediatric Oncology.

JAMA Oncol 2017 Sep;3(9):1214-1220

Division of Quality of Life and Palliative Care, Department of Oncology, St Jude Children's Research Hospital, Memphis, Tennessee.

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http://dx.doi.org/10.1001/jamaoncol.2017.0368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5824292PMC
September 2017

Public preferences on written informed consent for low-risk pragmatic clinical trials in Spain.

Br J Clin Pharmacol 2017 Sep 11;83(9):1921-1931. Epub 2017 Jun 11.

Section on Research Ethics, Department of Bioethics, NIH Clinical Center, 10 Center Drive, Bethesda, MD, 20814,, USA.

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http://dx.doi.org/10.1111/bcp.13305DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582372PMC
September 2017

Patients' beliefs regarding informed consent for low-risk pragmatic trials.

BMC Med Res Methodol 2017 Sep 18;17(1):145. Epub 2017 Sep 18.

Section on Research Ethics, Department of Bioethics, NIH Clinical Center, 10 Center Dr, Bethesda, MD, 20814, USA.

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http://dx.doi.org/10.1186/s12874-017-0424-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5604493PMC
September 2017

Comparative effectiveness research: what to do when experts disagree about risks.

BMC Med Ethics 2017 Jun 19;18(1):42. Epub 2017 Jun 19.

Department of Bioethics, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1186/s12910-017-0202-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477349PMC
June 2017

Why is Coerced Consent Worse Than No Consent and Deceived Consent?

J Med Philos 2017 Apr;42(2):114-131

NIH Clinical Center, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1093/jmp/jhw064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901088PMC
April 2017

Targeted Consent for Research on Standard of Care Interventions in the Emergency Setting.

Crit Care Med 2017 Jan;45(1):e105-e110

1Department of Bioethics, NIH Clinical Center, National Institutes of Health, Bethesda, MD. 2Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA. 3Department of Epidemiology, Emory University Rollins School of Public Health, Atlanta, GA. 4Department of Emergency Medicine, University of Michigan Medical School, Ann Arbor, MI. 5Office of Emergency Care Research, National Institute of General Medical Sciences, National Institutes of Health, Bethesda, MD.

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http://dx.doi.org/10.1097/CCM.0000000000002023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161670PMC
January 2017

The Theory and Practice of Surrogate Decision-Making.

Authors:
David Wendler

Hastings Cent Rep 2017 01;47(1):29-31

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http://dx.doi.org/10.1002/hast.671DOI Listing
January 2017

Addressing exploitation of poor clinical trial participants in North America and the European Union.

Eur J Intern Med 2016 Oct 15;34:e37-e38. Epub 2016 Jul 15.

Department of Bioethics, NIH Clinical Center, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.ejim.2016.06.026DOI Listing
October 2016

Is the French clinical trials regulation discriminatory?

Eur J Intern Med 2016 Oct 9;34:e35-e36. Epub 2016 Aug 9.

Department of Bioethics, NIH Clinical Center, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.ejim.2016.07.019DOI Listing
October 2016

Ensuring Respect for Human Research Participants: Institutional Review Boards and Sharing Results From Research.

JAMA 2016 Sep;316(11):1149-1150

Clinical Center, Department of Bioethics, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1001/jama.2016.7970DOI Listing
September 2016

Research involving pediatric stem cell donors: A way forward.

Clin Trials 2016 06 17;13(3):304-10. Epub 2016 Feb 17.

Department of Bioethics, NIH Clinical Center, Bethesda, MD, USA.

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http://dx.doi.org/10.1177/1740774515627156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965294PMC
June 2016

When clinical care is like research: the need for review and consent.

Theor Med Bioeth 2016 Jun;37(3):193-209

Department of Sociology, Princeton University, Princeton, NJ, USA.

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http://dx.doi.org/10.1007/s11017-016-9364-xDOI Listing
June 2016

The Potential for Infrastructure Benefits and the Responsiveness Requirement.

Authors:
David Wendler

Am J Bioeth 2016 06;16(6):1-2

a NIH Clinical Center.

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http://dx.doi.org/10.1080/15265161.2016.1184508DOI Listing
June 2016

The potential exploitation of research participants in high income countries who lack access to health care.

Br J Clin Pharmacol 2016 May 29;81(5):857-64. Epub 2016 Feb 29.

Department of Bioethics, NIH Clinical Center, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1111/bcp.12879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834591PMC
May 2016

Risks of phase I research with healthy participants: A systematic review.

Clin Trials 2016 Apr 8;13(2):149-60. Epub 2015 Sep 8.

Department of Bioethics, NIH Clinical Center, Bethesda, MD, USA.

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http://dx.doi.org/10.1177/1740774515602868DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783291PMC
April 2016

Do Patients Want their Families or their Doctors to Make Treatment Decisions in the Event of Incapacity, and Why?

AJOB Empir Bioeth 2016 26;7(4):251-259. Epub 2016 Apr 26.

Department of Social Science, Health & Medicine, King's College London.

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http://dx.doi.org/10.1080/23294515.2016.1182235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609846PMC
April 2016

A new method for making treatment decisions for incapacitated patients: what do patients think about the use of a patient preference predictor?

J Med Ethics 2016 Apr 29;42(4):235-41. Epub 2016 Jan 29.

Department of Social Science, Health & Medicine, King's College London, London, United Kingdom.

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http://dx.doi.org/10.1136/medethics-2015-103001DOI Listing
April 2016

Adolescent Research Participants' Descriptions of Medical Research.

AJOB Empir Bioeth 2016 Jan 19;7(1):1-7. Epub 2015 Feb 19.

Department of Bioethics, NIH Clinical Center.

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http://dx.doi.org/10.1080/23294515.2015.1017059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4797334PMC
January 2016

Patients' priorities for treatment decision making during periods of incapacity: quantitative survey.

Palliat Support Care 2015 Oct 2;13(5):1165-83. Epub 2014 Oct 2.

Department of Bioethics,The Clinical Center, National Institutes of Health,Bethesda,Maryland.

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http://dx.doi.org/10.1017/S1478951514001096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535787PMC
October 2015

Examining the ethics of clinical use of unproven interventions outside of clinical trials during the Ebola epidemic.

Am J Bioeth 2015 ;15(4):11-6

a Clinical Center Department of Bioethics, Division of AIDS, National Institutes of Health , Bethesda , Maryland , USA.

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http://www.tandfonline.com/doi/full/10.1080/15265161.2015.10
Publisher Site
http://dx.doi.org/10.1080/15265161.2015.1010996DOI Listing
October 2015

Involving Communities in Deciding What Benefits They Receive in Multinational Research.

J Med Philos 2015 Oct 29;40(5):584-600. Epub 2015 Jul 29.

National Institutes of Health, Bethesda, Maryland, USA National Institutes of Health, Bethesda, Maryland, USA.

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https://academic.oup.com/jmp/article-lookup/doi/10.1093/jmp/
Publisher Site
http://dx.doi.org/10.1093/jmp/jhv017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573657PMC
October 2015

Is there a role for assent or dissent in animal research?

Camb Q Healthc Ethics 2015 Oct;24(4):459-72

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http://dx.doi.org/10.1017/S0963180115000110DOI Listing
October 2015

Considerations in the evaluation and determination of minimal risk in pragmatic clinical trials.

Clin Trials 2015 Oct 15;12(5):485-93. Epub 2015 Sep 15.

Research Support Committee, Phelan-McDermid Syndrome Foundation, Venice, FL, USA.

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http://dx.doi.org/10.1177/1740774515597687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703320PMC
October 2015

Justice and nontherapeutic pediatric research.

Authors:
David Wendler

Am J Bioeth 2014 ;14(9):13-5

a National Institutes of Health Clinical Center.

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http://dx.doi.org/10.1080/15265161.2014.936250DOI Listing
September 2015

Clarifying substituted judgement: the endorsed life approach.

J Med Ethics 2015 Sep 30;41(9):723-30. Epub 2014 Oct 30.

Department of Bioethics, NIH Clinical Center, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1136/medethics-2013-101852DOI Listing
September 2015

Clarifying and defending the endorsed life approach to surrogate decision-making.

J Med Ethics 2015 Sep 28;41(9):736-8. Epub 2015 Jul 28.

Department of Philosophy, University of North Carolina, North Carolina, USA.

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http://dx.doi.org/10.1136/medethics-2015-102950DOI Listing
September 2015

Should all research subjects be treated the same?

Hastings Cent Rep 2015 Jan-Feb;45(1):17-20

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http://dx.doi.org/10.1002/hast.414DOI Listing
August 2015

Clinical research: Should patients pay to play?

Sci Transl Med 2015 Jul;7(298):298ps16

Department of Philosophy, Stanford University, Stanford, CA 94305-2155, USA.

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http://dx.doi.org/10.1126/scitranslmed.aac5204DOI Listing
July 2015

"Targeted" consent for pragmatic clinical trials.

Authors:
David Wendler

J Gen Intern Med 2015 May 14;30(5):679-82. Epub 2015 Jan 14.

Department of Bioethics, NIH Clinical Center, Building 10, Room 1C118, Bethesda, MD, 20892-1156, USA,

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http://link.springer.com/10.1007/s11606-014-3169-2
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http://dx.doi.org/10.1007/s11606-014-3169-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395600PMC
May 2015

Genetic research on biospecimens poses minimal risk.

Trends Genet 2015 Jan 16;31(1):11-5. Epub 2014 Dec 16.

Department of Social Science, Health & Medicine, King's College London, London, England, UK.

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http://dx.doi.org/10.1016/j.tig.2014.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281290PMC
January 2015

The ethics of peer review in bioethics.

J Med Ethics 2014 Oct 16;40(10):697-701. Epub 2013 Oct 16.

Department of Bioethics, NIH Clinical Center, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1136/medethics-2013-101364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155015PMC
October 2014

Research on very early ART in neonates at risk of HIV infection.

Lancet Infect Dis 2014 Sep;14(9):797

NIH Department of Bioethics, 10 Center Dr, 10/1C118, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/S1473-3099(14)70893-XDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347665PMC
September 2014

Evaluating the risks of clinical research: direct comparative analysis.

J Child Adolesc Psychopharmacol 2014 Sep;24(7):390-8

1 Department of Social Science, Health & Medicine, King's College London , United Kingdom .

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http://dx.doi.org/10.1089/cap.2014.0039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4162436PMC
September 2014

Protections for clinical trials in low and middle income countries need strengthening not weakening.

BMJ 2014 Jul 4;349:g4254. Epub 2014 Jul 4.

Unit on Vulnerable Populations, Department of Bioethics, NIH Clinical Center, Bethesda, Maryland, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688422PMC
http://dx.doi.org/10.1136/bmj.g4254DOI Listing
July 2014

What should be disclosed to research participants?

Authors:
David Wendler

Am J Bioeth 2013 ;13(12):3-8

a Department of Bioethics , NIH Clinical Center.

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http://dx.doi.org/10.1080/15265161.2013.851578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154248PMC
June 2014

Problems with the consensus definition of the therapeutic misconception.

Authors:
David S Wendler

J Clin Ethics 2013 ;24(4):387-94

Department of Bioethics, NIH Clinical Center, Bethesda, Maryland, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4155983PMC
April 2014

Use of a patient preference predictor to help make medical decisions for incapacitated patients.

J Med Philos 2014 Apr 13;39(2):104-29. Epub 2014 Feb 13.

*Department of Social Science, Health & Medicine, King's College London, Strand, London WC2R 2LS, UK.

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http://dx.doi.org/10.1093/jmp/jhu001DOI Listing
April 2014

Treatment decision making for incapacitated patients: is development and use of a patient preference predictor feasible?

J Med Philos 2014 Apr 20;39(2):130-52. Epub 2014 Feb 20.

*Department of Social Science, Health & Medicine, King's College London, Strand, London WC2R 2LS, UK.

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http://dx.doi.org/10.1093/jmp/jhu006DOI Listing
April 2014

Should protections for research with humans who cannot consent apply to research with nonhuman primates?

Authors:
David Wendler

Theor Med Bioeth 2014 Apr;35(2):157-73

Department of Bioethics, NIH Clinical Center, Building 10, Room 1C118, Bethesda, MD, 20892-1156, USA,

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http://dx.doi.org/10.1007/s11017-014-9285-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5524520PMC
April 2014

Do U.S. regulations allow more than minor increase over minimal risk pediatric research? Should they?

Authors:
David Wendler

IRB 2013 Nov-Dec;35(6):1-8

Unit on Vulnerable Populations, Department of Bioethics, NIH Clinical Center, National Institutes of Health, Bethesda, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142753PMC
March 2014

Declaration of Helsinki and protection for vulnerable research participants--reply.

JAMA 2014 Mar;311(12):1252-3

Department of Medical Ethics and Health Policy, University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1001/jama.2014.1281DOI Listing
March 2014

Broad versus blanket consent for research with human biological samples.

Authors:
David Wendler

Hastings Cent Rep 2013 Sep-Oct;43(5):3-4

Department of Bioethics National Institutes of Health Clinical Center.

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http://dx.doi.org/10.1002/hast.200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520538PMC
December 2013

The 50th anniversary of the Declaration of Helsinki: progress but many remaining challenges.

JAMA 2013 Nov;310(20):2143-4

Department of Bioethics, Clinical Center, National Institutes of Health, Bethesda, Maryland2Fogarty International Center, National Institutes of Health, Bethesda, Maryland.

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http://dx.doi.org/10.1001/jama.2013.281632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203648PMC
November 2013

Disclosure of incidental findings from next-generation sequencing in pediatric genomic research.

Pediatrics 2013 Mar 11;131(3):564-71. Epub 2013 Feb 11.

Department of Bioethics, Clinical Center, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892-1156, USA.

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http://dx.doi.org/10.1542/peds.2012-0084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581837PMC
March 2013

Making the transition to a learning health care system. Commentary.

Hastings Cent Rep 2013 Jan-Feb;Spec No:S32-3

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http://dx.doi.org/10.1002/hast.137DOI Listing
March 2013

Time to stop worrying about the therapeutic misconception.

Authors:
David S Wendler

J Clin Ethics 2012 ;23(3):272-87

Department of Bioethics, National Institutes of Health Clinical Center, Bethesda, Maryland, USA.

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January 2013

Taking the measure of the therapeutic misconception.

Authors:
David Wendler

Clin Trials 2012 Dec;9(6):762-4; discussion 765-6

Department of Bioethics, NIH Clinical Center, Bethesda, MD 20892-1156, USA.

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http://dx.doi.org/10.1177/1740774512456778DOI Listing
December 2012

Views of adolescents and parents on pediatric research without the potential for clinical benefit.

Pediatrics 2012 Oct 10;130(4):692-9. Epub 2012 Sep 10.

Department of Bioethics, NIH Clinical Center, Building 10, Room 1C118, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1542/peds.2012-0068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457618PMC
October 2012

Shared medical decision-making: considering what options to present based on an ethical analysis of the treatment of brain tumors in very young children.

Pediatr Blood Cancer 2012 Aug 22;59(2):216-20. Epub 2012 Apr 22.

Department of Bioethics, NIH Clinical Center, Bethesda, Maryland; Johns Hopkins Pediatric Oncology, Baltimore, Maryland, USA.

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http://dx.doi.org/10.1002/pbc.24189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374065PMC
August 2012

The moral duty to buy health insurance.

JAMA 2012 Jul;308(2):137-8

Department of Bioethics, NIH Clinical Center, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1001/jama.2012.5648DOI Listing
July 2012

Systematic review: Individuals' goals for surrogate decision-making.

J Am Geriatr Soc 2012 May 3;60(5):884-95. Epub 2012 Apr 3.

University of Michigan Law School, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1111/j.1532-5415.2012.03937.xDOI Listing
May 2012

Consent for research with biological samples: one-time general consent versus a gift model.

Authors:
David Wendler

Ann Intern Med 2012 Apr;156(8):596-8

National Institutes of Health Clinical Center, Bethesda, Maryland 20892-1156, USA.

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http://dx.doi.org/10.7326/0003-4819-156-8-201204170-00008DOI Listing
April 2012

Using data to improve surrogate consent for clinical research with incapacitated adults.

J Empir Res Hum Res Ethics 2012 Apr;7(2):37-50

Department of Bioethics, National Institutes of Health, Bethesda, MD 20892-1156, USA.

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http://dx.doi.org/10.1525/jer.2012.7.2.37DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474197PMC
April 2012

A new justification for pediatric research without the potential for clinical benefit.

Authors:
David Wendler

Am J Bioeth 2012 ;12(1):23-31

NIH Clinical Center, Bethesda, MD 20892-1156, USA.

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March 2012

A proposal and prototype for a Research Risk Repository to improve the protection of research participants.

Clin Trials 2011 Dec 22;8(6):705-15. Epub 2011 Aug 22.

Institute of Biomedical Ethics, University of Zurich, Zurich, Switzerland.

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http://journals.sagepub.com/doi/10.1177/1740774511414595
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December 2011

What we worry about when we worry about the ethics of clinical research.

Authors:
David Wendler

Theor Med Bioeth 2011 Jun;32(3):161-80

Department of Bioethics, NIH Clinical Center, Building 10, Room 1C118, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s11017-011-9176-yDOI Listing
June 2011

A framework for risk-benefit evaluations in biomedical research.

Kennedy Inst Ethics J 2011 Jun;21(2):141-79

Institute of Biomedical Ethics, University of Zurich.

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http://dx.doi.org/10.1353/ken.2011.0007DOI Listing
June 2011

The use of human tissues in research: what do we owe the research subjects?

Clin Chem 2011 Apr 4;57(4):540-4. Epub 2011 Jan 4.

Departments of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA.

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http://dx.doi.org/10.1373/clinchem.2010.154989DOI Listing
April 2011

How to enroll participants in research ethically.

Authors:
David Wendler

JAMA 2011 Apr;305(15):1587-8

Department of Bioethics, National Institutes of Health Clinical Center, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1001/jama.2011.421DOI Listing
April 2011

Systematic review: the effect on surrogates of making treatment decisions for others.

Ann Intern Med 2011 Mar;154(5):336-46

National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.7326/0003-4819-154-5-201103010-00008DOI Listing
March 2011

Clinician integrity and limits to patient autonomy.

JAMA 2011 Feb;305(5):495-9

Children's Mercy Bioethics Center, Children's Mercy Hospital, 2401 Gilham Rd, Kansas City, MO 64108, USA.

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http://dx.doi.org/10.1001/jama.2011.32DOI Listing
February 2011

Does it matter whether investigators intend to benefit research subjects?

Kennedy Inst Ethics J 2010 Dec;20(4):353-70

Department of Bioethics, NIH Clinical Center, National Institutes of Health, Bethesda, MD, USA.

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December 2010

Can we improve treatment decision-making for incapacitated patients?

Hastings Cent Rep 2010 Sep-Oct;40(5):36-45

Department of Bioethics, National Institutes of Health Clinical Center, USA.

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http://dx.doi.org/10.1353/hcr.2010.0001DOI Listing
November 2010