David Weinshenker

David Weinshenker

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David Weinshenker

Publications by authors named "David Weinshenker"

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Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease.

Neurobiol Dis 2019 10 15;130:104511. Epub 2019 Jun 15.

Department of Psychiatry, Harvard Medical School, Boston, MA, USA; Laboratory of Psychiatric and Molecular Neuroscience, McLean Hospital, Belmont, MA, USA.

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http://dx.doi.org/10.1016/j.nbd.2019.104511DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689433PMC
October 2019

Chronic adolescent stress sex-specifically alters the hippocampal transcriptome in adulthood.

Neuropsychopharmacology 2019 06 23;44(7):1207-1215. Epub 2019 Jan 23.

Department of Anatomy and Neurobiology, Virginia Commonwealth University, Richmond, VA, USA.

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http://dx.doi.org/10.1038/s41386-019-0321-zDOI Listing
June 2019

Locomotor sensitization to cocaine in adolescent and adult female Wistar rats.

Behav Brain Res 2018 09 25;349:158-162. Epub 2018 Apr 25.

Department of Anatomy & Neurobiology, Virginia Commonwealth University, Richmond, VA, 23284, United States; Department of Physiology, Emory University, Atlanta, GA, 30322, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bbr.2018.04.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993637PMC
September 2018

Down but Not Out: The Consequences of Pretangle Tau in the Locus Coeruleus.

Neural Plast 2017 5;2017:7829507. Epub 2017 Sep 5.

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1155/2017/7829507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605916PMC
June 2018

Long Road to Ruin: Noradrenergic Dysfunction in Neurodegenerative Disease.

Trends Neurosci 2018 04 20;41(4):211-223. Epub 2018 Feb 20.

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tins.2018.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5878728PMC
April 2018

Effects of disulfiram on choice behavior in a rodent gambling task: association with catecholamine levels.

Psychopharmacology (Berl) 2018 01 30;235(1):23-35. Epub 2017 Oct 30.

Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, University of Toronto, 33 Russell Street, Toronto, M5S 2S1, Canada.

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http://dx.doi.org/10.1007/s00213-017-4744-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5750121PMC
January 2018

Arresting the Development of Addiction: The Role of -Arrestin 2 in Drug Abuse.

J Pharmacol Exp Ther 2017 06 16;361(3):341-348. Epub 2017 Mar 16.

Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia

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http://dx.doi.org/10.1124/jpet.117.240622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443318PMC
June 2017

Altered motility of plaque-associated microglia in a model of Alzheimer's disease.

Neuroscience 2016 08 7;330:410-20. Epub 2016 Jun 7.

Department of Pharmacology, Emory University, Rollins Research Center, 1510 Clifton Road, Atlanta, GA 30322, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuroscience.2016.05.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927418PMC
August 2016

A Method for Psychosocial Stress-Induced Reinstatement of Cocaine Seeking in Rats.

Biol Psychiatry 2016 06 8;79(11):940-6. Epub 2015 Jul 8.

Department of Human Genetics, Emory University School of Medicine, Emory University, Atlanta, Georgia. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2015.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706515PMC
June 2016

Regulation of neurological and neuropsychiatric phenotypes by locus coeruleus-derived galanin.

Brain Res 2016 06 20;1641(Pt B):320-37. Epub 2015 Nov 20.

Neuroscience Program, Biomedical and Health Sciences Institute and Psychology Department, University of Georgia, Athens, GA 30602, USA. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2015.11.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4874918PMC
June 2016

Bacterial Adrenergic Sensors Regulate Virulence of Enteric Pathogens in the Gut.

MBio 2016 06 7;7(3). Epub 2016 Jun 7.

Department of Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas, USA

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http://dx.doi.org/10.1128/mBio.00826-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959670PMC
June 2016

Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor.

Hum Mol Genet 2015 Oct 21;24(19):5512-23. Epub 2015 Jul 21.

Department of Cell Biology, Emory University, Atlanta, GA 30322, USA, Center for Social Translational Neuroscience, Emory University, Atlanta, GA 30322, USA,

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http://dx.doi.org/10.1093/hmg/ddv282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572075PMC
October 2015

A new knock-in mouse model of l-DOPA-responsive dystonia.

Brain 2015 Oct 27;138(Pt 10):2987-3002. Epub 2015 Jul 27.

1 Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA 6 Department of Neurology, Emory University School of Medicine, Atlanta, GA 30322, USA

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http://dx.doi.org/10.1093/brain/awv212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4627353PMC
October 2015

Norepinephrine Protects against Amyloid-β Toxicity via TrkB.

J Alzheimers Dis 2015 ;44(1):251-60

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.3233/JAD-141062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714587PMC
September 2015

The effects of post-extinction exercise on cocaine-primed and stress-induced reinstatement of cocaine seeking in rats.

Psychopharmacology (Berl) 2015 Apr 31;232(8):1395-403. Epub 2014 Oct 31.

Neuroscience Graduate Program, Emory University, Atlanta, GA, 30322, USA.

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http://dx.doi.org/10.1007/s00213-014-3778-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388768PMC
April 2015

Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity.

Circ Res 2014 Dec 17;115(12):1017-25. Epub 2014 Oct 17.

From the Center for Pharmacogenomics, College of Medicine, The Ohio State University, Columbus (E.S.B., J.K.P., W.S.); Department of Human Genetics, Emory University School of Medicine, Atlanta, GA (D.W., J.F.C.); Center for Systems Genomics, Pennsylvania State University, University Park (A.V., S.A.P., M.D.R.); Department of Genetics, University of North Carolina School of Medicine, Chapel Hill (L.A.L.); Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson (J.G.W.); The Sigfried and Janet Weis Center for Research, Geisinger Health System, Danville, PA (H.K., G.T., D.J.C.); Institute for Personalized Medicine, The Pennsylvania State University College of Medicine, Hershey (G.S.G.); Center for Human Genetics, Marshfield Clinic Research Foundation, WI (M.H.B., S.J.H.); and Department of Psychology, The University of Chicago, IL (G.J.N.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.304398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258174PMC
December 2014

Effects of pharmacologic dopamine β-hydroxylase inhibition on cocaine-induced reinstatement and dopamine neurochemistry in squirrel monkeys.

J Pharmacol Exp Ther 2014 Jul 9;350(1):144-52. Epub 2014 May 9.

Yerkes National Primate Research Center, Division of Neuropharmacology and Neurologic Diseases (D.A.C., H.L.K., L.L.H.), Department of Pharmacology (H.L.K., L.L.H.), Department of Human Genetics (D.A.C., D.F.M., K.T.S., D.W.), and Department of Psychiatry and Behavioral Sciences (L.L.H.), Emory University, Atlanta, Georgia

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http://dx.doi.org/10.1124/jpet.113.212357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056266PMC
July 2014

Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease.

Alzheimers Res Ther 2013 29;5(2):21. Epub 2013 Apr 29.

Department of Neurology, Suite 6000 WMB, 101 Woodruff Circle, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1186/alzrt175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3706916PMC
June 2014

The role of the neurokinin-1 receptor in stress-induced reinstatement of alcohol and cocaine seeking.

Neuropsychopharmacology 2014 Apr 31;39(5):1093-101. Epub 2013 Oct 31.

Department of Human Genetics, Emory University, Atlanta, GA, USA.

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http://dx.doi.org/10.1038/npp.2013.309DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957103PMC
April 2014

Adrenaline rush: the role of adrenergic receptors in stimulant-induced behaviors.

Mol Pharmacol 2014 Apr 5;85(4):640-50. Epub 2014 Feb 5.

Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia.

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http://dx.doi.org/10.1124/mol.113.090118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965894PMC
April 2014

7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease.

Neuropsychopharmacology 2014 Feb 11;39(3):638-50. Epub 2013 Sep 11.

Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1038/npp.2013.243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895241PMC
February 2014

BDNF deletion or TrkB impairment in amygdala inhibits both appetitive and aversive learning.

J Neurosci 2014 Feb;34(7):2444-50

Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, Department of Psychiatry and Behavioral Sciences, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia 30329, and Howard Hughes Medical Institute, Chevy Chase, Maryland 20815.

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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.4085-12.2
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http://dx.doi.org/10.1523/JNEUROSCI.4085-12.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921419PMC
February 2014

Dopamine β-hydroxylase inhibitors enhance the discriminative stimulus effects of cocaine in rats.

J Pharmacol Exp Ther 2013 Dec 25;347(3):564-73. Epub 2013 Sep 25.

Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia (D.F.M., D.W.); and Graduate Program in Neuroscience, Emory University, Atlanta, Georgia (L.M.D.).

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http://dx.doi.org/10.1124/jpet.113.207746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3836309PMC
December 2013

Antidepressant and anticonvulsant effects of exercise in a rat model of epilepsy and depression comorbidity.

Epilepsy Behav 2013 Oct 8;29(1):47-52. Epub 2013 Aug 8.

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.yebeh.2013.06.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783960PMC
October 2013

Chronic inhibition of dopamine β-hydroxylase facilitates behavioral responses to cocaine in mice.

PLoS One 2012 27;7(11):e50583. Epub 2012 Nov 27.

Department of Human Genetics, Emory University School of Medicine, Atlanta, Georgia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0050583PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507785PMC
May 2013

The selective dopamine β-hydroxylase inhibitor nepicastat attenuates multiple aspects of cocaine-seeking behavior.

Neuropsychopharmacology 2013 May 3;38(6):1032-8. Epub 2013 Jan 3.

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1038/npp.2012.267DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629392PMC
May 2013

Rhythm and blues: animal models of epilepsy and depression comorbidity.

Biochem Pharmacol 2013 Jan 23;85(2):135-46. Epub 2012 Aug 23.

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00062952120057
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http://dx.doi.org/10.1016/j.bcp.2012.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116104PMC
January 2013

Seizure susceptibility and epileptogenesis in a rat model of epilepsy and depression co-morbidity.

Neuropsychopharmacology 2012 Dec 8;37(13):2756-63. Epub 2012 Aug 8.

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA.

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http://dx.doi.org/10.1038/npp.2012.141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499730PMC
December 2012

Operant psychostimulant self-administration in a rat model of depression.

Pharmacol Biochem Behav 2012 Dec 23;103(2):380-5. Epub 2012 Sep 23.

Department of Human Genetics, Emory University School of Medicine, Whitehead 301, 615 Michael St., Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.pbb.2012.09.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494799PMC
December 2012

Physiological and genomic consequences of adrenergic deficiency during embryonic/fetal development in mice: impact on retinoic acid metabolism.

Physiol Genomics 2012 Oct 21;44(19):934-47. Epub 2012 Aug 21.

Burnett School of Biomedical Sciences, University of Central Florida College of Medicine, Orlando, Florida 32827, USA.

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http://dx.doi.org/10.1152/physiolgenomics.00180.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472461PMC
October 2012

Adrenergic deficiency leads to impaired electrical conduction and increased arrhythmic potential in the embryonic mouse heart.

Biochem Biophys Res Commun 2012 Jul 7;423(3):536-41. Epub 2012 Jun 7.

Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, 6900 Lake Nona Blvd, Orlando, FL 32827, USA.

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http://dx.doi.org/10.1016/j.bbrc.2012.05.163DOI Listing
July 2012

Cocaine sobers up.

Nat Med 2010 Sep;16(9):969-70

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http://www.nature.com/articles/nm0910-969
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http://dx.doi.org/10.1038/nm0910-969DOI Listing
September 2010

Good night and good luck: norepinephrine in sleep pharmacology.

Biochem Pharmacol 2010 Mar 13;79(6):801-9. Epub 2009 Oct 13.

Department of Human Genetics, Emory University, Atlanta, GA 30322, United States.

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http://linkinghub.elsevier.com/retrieve/pii/S000629520900856
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http://dx.doi.org/10.1016/j.bcp.2009.10.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2812689PMC
March 2010

QseC mediates Salmonella enterica serovar typhimurium virulence in vitro and in vivo.

Infect Immun 2010 Mar 22;78(3):914-26. Epub 2009 Dec 22.

University of Texas Southwestern Medical Center, Department of Microbiology, Dallas, TX 75390-9048, USA.

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http://dx.doi.org/10.1128/IAI.01038-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2825943PMC
March 2010

mechanisms of disulfiram-induced cocaine abstinence: antabuse and cocaine relapse.

Mol Interv 2009 Aug;9(4):175-87

Department of Human Genetics, Emory University School of Medicine, Whitehead 301, 615 Michael St, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1124/mi.9.4.6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861803PMC
August 2009

Amitriptyline is a TrkA and TrkB receptor agonist that promotes TrkA/TrkB heterodimerization and has potent neurotrophic activity.

Chem Biol 2009 Jun;16(6):644-56

Department of Pathology and Laboratory Medicine, Emory University, 615 Michael Street, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.chembiol.2009.05.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844702PMC
June 2009

Nonmotor symptoms of Parkinson's disease revealed in an animal model with reduced monoamine storage capacity.

J Neurosci 2009 Jun;29(25):8103-13

Center for Neurodegenerative Disease and Department of Environmental and Occupational Health, Rollins School of Public Health, Emory University, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1495-09.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813143PMC
June 2009

Genetic dissection of alpha2-adrenoceptor functions in adrenergic versus nonadrenergic cells.

Mol Pharmacol 2009 May 27;75(5):1160-70. Epub 2009 Feb 27.

Institute of Experimental and Clinical Pharmacology and Toxicology, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1124/mol.109.054544DOI Listing
May 2009

Noradrenergic depression of neuronal excitability in the entorhinal cortex via activation of TREK-2 K+ channels.

J Biol Chem 2009 Apr 25;284(16):10980-91. Epub 2009 Feb 25.

Department of Pharmacology, Physiology and Therapeutics, School of Medicine and Health Sciences, University of North Dakota, Grand Forks, North Dakota 58203.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M806760200
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http://dx.doi.org/10.1074/jbc.M806760200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667783PMC
April 2009

The contribution of norepinephrine and orexigenic neuropeptides to the anticonvulsant effect of the ketogenic diet.

Epilepsia 2008 Nov;49 Suppl 8:104-7

Department of Human Genetics, Emory University, Atlanta, Georgia 30322, USA.

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http://doi.wiley.com/10.1111/j.1528-1167.2008.01850.x
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http://dx.doi.org/10.1111/j.1528-1167.2008.01850.xDOI Listing
November 2008

Neuroscience: fragile dopamine.

Nature 2008 Oct;455(7213):607-8

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http://www.nature.com/doifinder/10.1038/455607a
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http://dx.doi.org/10.1038/455607aDOI Listing
October 2008

Possible dopaminergic stimulation of locus coeruleus alpha1-adrenoceptors involved in behavioral activation.

Synapse 2008 Jul;62(7):516-23

Department of Psychiatry, New York University School of Medicine, New York, New York 10016, USA.

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http://dx.doi.org/10.1002/syn.20517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754581PMC
July 2008

Norepinephrine signaling through beta-adrenergic receptors is critical for expression of cocaine-induced anxiety.

Biol Psychiatry 2008 Jun 20;63(11):1007-12. Epub 2008 Feb 20.

Department of Human Genetics, Emory University, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.biopsych.2007.10.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2405894PMC
June 2008

Effects of disulfiram and dopamine beta-hydroxylase knockout on cocaine-induced seizures.

Pharmacol Biochem Behav 2008 Jun 12;89(4):556-62. Epub 2008 Feb 12.

Department of Human Genetics, Emory University, 301 Whitehead Biomedical Research Building, 615 Michael Street, Atlanta, GA 30322, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00913057080005
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http://dx.doi.org/10.1016/j.pbb.2008.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2386143PMC
June 2008

Functional consequences of locus coeruleus degeneration in Alzheimer's disease.

Curr Alzheimer Res 2008 Jun;5(3):342-5

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.

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June 2008

There and back again: a tale of norepinephrine and drug addiction.

Neuropsychopharmacology 2007 Jul 13;32(7):1433-51. Epub 2006 Dec 13.

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://www.nature.com/articles/1301263
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http://dx.doi.org/10.1038/sj.npp.1301263DOI Listing
July 2007

Behavioral genetics of caenorhabditis elegans unc-103-encoded erg-like K(+) channel.

J Neurogenet 2006 Jan-Jun;20(1-2):41-66

Department of Genome Sciences, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1080/01677060600788826DOI Listing
May 2007

Rats bred for susceptibility to depression-like phenotypes have higher kainic acid-induced seizure mortality than their depression-resistant counterparts.

Epilepsy Res 2007 May 2;74(2-3):140-6. Epub 2007 Apr 2.

Department of Human Genetics, Emory University School of Medicine, Whitehead 301, 615 Michael Street, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.eplepsyres.2007.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1940038PMC
May 2007

Oxyntomodulin increases intrinsic heart rate in mice independent of the glucagon-like peptide-1 receptor.

Am J Physiol Regul Integr Comp Physiol 2007 Feb 12;292(2):R962-70. Epub 2006 Oct 12.

Department of Biology, Williams College, Williamstown, MA 01267, USA.

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http://www.physiology.org/doi/10.1152/ajpregu.00405.2006
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http://dx.doi.org/10.1152/ajpregu.00405.2006DOI Listing
February 2007

The effects of norepinephrine transporter inactivation on locomotor activity in mice.

Biol Psychiatry 2006 Nov 7;60(10):1046-52. Epub 2006 Aug 7.

Department of Human Genetics, Emory University School of Medicine, 615 Michael Street, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.biopsych.2006.03.057DOI Listing
November 2006

Dopamine beta-hydroxylase knockout mice have alterations in dopamine signaling and are hypersensitive to cocaine.

Neuropsychopharmacology 2006 Oct 14;31(10):2221-30. Epub 2005 Dec 14.

Department of Human Genetics, Emory University, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1038/sj.npp.1301000DOI Listing
October 2006

Psychosis pathways converge via D2high dopamine receptors.

Synapse 2006 Sep;60(4):319-46

Department of Pharmacology, University of Toronto, and Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada M5S 1A8.

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http://dx.doi.org/10.1002/syn.20303DOI Listing
September 2006

Analysis of brain adrenergic receptors in dopamine-beta-hydroxylase knockout mice.

Brain Res 2006 Sep 18;1109(1):45-53. Epub 2006 Jul 18.

Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198-5800, and Veterans Administration Puget Sound Health Care System, Seattle, WA 98108, USA.

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http://dx.doi.org/10.1016/j.brainres.2006.06.033DOI Listing
September 2006

The effects of chronic norepinephrine transporter inactivation on seizure susceptibility in mice.

Neuropsychopharmacology 2006 Apr;31(4):730-8

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1038/sj.npp.1300847DOI Listing
April 2006

A ketogenic diet and knockout of the norepinephrine transporter both reduce seizure severity in mice.

Epilepsy Res 2006 Mar 13;68(3):207-11. Epub 2005 Dec 13.

Department of Biology, Georgetown University, Washington, DC 20057-1229, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09201211050029
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http://dx.doi.org/10.1016/j.eplepsyres.2005.11.002DOI Listing
March 2006

Role of noradrenergic signaling by the nucleus tractus solitarius in mediating opiate reward.

Science 2006 Feb;311(5763):1017-20

Howard Hughes Medical Institute and Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1126/science.1119311DOI Listing
February 2006

Effects of dopamine beta-hydroxylase genotype and disulfiram inhibition on catecholamine homeostasis in mice.

Psychopharmacology (Berl) 2005 Nov 22;183(1):72-80. Epub 2005 Oct 22.

Department of Human Genetics, Emory University School of Medicine, Whitehead 301, 615 Michael St., Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1007/s00213-005-0139-8DOI Listing
November 2005

A new method for identifying informative genetic markers in selectively bred rats.

Mamm Genome 2005 Oct 29;16(10):784-91. Epub 2005 Oct 29.

Department of Human Genetics, Emory University, Whitehead 301, 615 Michael Street, Atlanta, Georgia 30322, USA.

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http://dx.doi.org/10.1007/s00335-005-0047-6DOI Listing
October 2005

Phenotypic analysis of mice deficient in the type 2 galanin receptor (GALR2).

Mol Cell Biol 2005 Jun;25(11):4804-11

Department of Physiology and Biophysics, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1128/MCB.25.11.4804-4811.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1140643PMC
June 2005

Genetic reduction of noradrenergic function alters social memory and reduces aggression in mice.

Behav Brain Res 2005 Jun;161(2):197-203

Department of Human Genetics, Emory University School of Medicine, Atlanta, GA 30322, USA.

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http://dx.doi.org/10.1016/j.bbr.2005.02.005DOI Listing
June 2005

Reduced anticonvulsant efficacy of valproic acid in dopamine beta-hydroxylase knockout mice.

Epilepsy Res 2005 Jun;65(1-2):23-31

Department of Human Genetics, Emory University School of Medicine, 301 Whitehead Biomedical Research Building, 615 Michael Street, Atlanta, GA 30322, USA.

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June 2005

Reduced MPTP toxicity in noradrenaline transporter knockout mice.

J Neurochem 2004 Dec;91(5):1116-24

Center for Neurodegenerative Disease, Emory University, Atlanta, Georgia, USA.

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http://doi.wiley.com/10.1111/j.1471-4159.2004.02785.x
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December 2004

The ketogenic diet does not alter brain expression of orexigenic neuropeptides.

Epilepsy Res 2004 Nov;62(1):35-9

Department of Human Genetics, Emory University School of Medicine, Whitehead Building, Suite 301, 615 Michael Street, Atlanta, GA 30322, USA.

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November 2004

Dbh(-/-) mice are hypotensive, have altered circadian rhythms, and have abnormal responses to dieting and stress.

Am J Physiol Regul Integr Comp Physiol 2004 Jan 11;286(1):R108-13. Epub 2003 Sep 11.

Department of Biology, Williams College, Williamstown, MA 01267, USA.

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http://www.physiology.org/doi/10.1152/ajpregu.00405.2003
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January 2004

Mice with chronic norepinephrine deficiency resemble amphetamine-sensitized animals.

Proc Natl Acad Sci U S A 2002 Oct 7;99(21):13873-7. Epub 2002 Oct 7.

Howard Hughes Medical Institute and Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1073/pnas.212519999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC129790PMC
October 2002

Regulation of norepinephrine transporter abundance by catecholamines and desipramine in vivo.

Brain Res 2002 Aug;946(2):239-46

Howard Hughes Medical Institute, Box 357370, University of Washington, Seattle 98195, USA.

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August 2002

The role of catecholamines in seizure susceptibility: new results using genetically engineered mice.

Pharmacol Ther 2002 Jun;94(3):213-33

Howard Hughes Medical Institute and Department of Biochemistry, University of Washington, Box 357370, Seattle, WA 98195, USA.

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June 2002

The NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenaline.

Proc Natl Acad Sci U S A 2002 Jan;99(2):1029-34

Department of Neurological Surgery, University of California, San Francisco, CA 94143-0112, USA.

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http://dx.doi.org/10.1073/pnas.012598599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC117425PMC
January 2002