David Wallach

David Wallach

UNVERIFIED PROFILE

Are you David Wallach?   Register this Author

Register author
David Wallach

David Wallach

Publications by authors named "David Wallach"

Are you David Wallach?   Register this Author

56Publications

925Reads

24Profile Views

The Tumor Necrosis Factor Family: Family Conventions and Private Idiosyncrasies.

Authors:
David Wallach

Cold Spring Harb Perspect Biol 2018 10 1;10(10). Epub 2018 Oct 1.

Department of Biomolecular Sciences, The Weizmann Institute of Science, 76100 Rehovot, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/cshperspect.a028431DOI Listing
October 2018

Programmed Cell Death in Immune Defense: Knowledge and Presumptions.

Immunity 2018 07;49(1):19-32

Department of Biotechnology, College of Biomedical and Health Science, Konkuk University, Chung-Ju 27478, Republic of Korea.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2018.06.019DOI Listing
July 2018

Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3.

Cell Death Differ 2018 06 17;25(6):1107-1117. Epub 2018 Apr 17.

Department of Biomolecular Sciences, The Weizmann Institute of Science, 76100, Rehovot, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41418-018-0104-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988659PMC
June 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Correction for Gyrd-Hansen et al., "Apoptosome-Independent Activation of the Lysosomal Cell Death Pathway by Caspase-9".

Mol Cell Biol 2018 01 29;38(2). Epub 2017 Dec 29.

Apoptosis Department and Centre for Genotoxic Stress, Institute for Cancer Biology, Danish Cancer Society, DK-2100 Copenhagen, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.00563-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5748465PMC
January 2018

MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation.

Immunity 2017 07 27;47(1):51-65.e7. Epub 2017 Jun 27.

Department of Biomolecular Sciences, The Weizmann Institute of Science, 76100 Rehovot, Israel. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2017.06.001DOI Listing
July 2017

Programmed necrosis in inflammation: Toward identification of the effector molecules.

Science 2016 Apr;352(6281):aaf2154

Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.aaf2154DOI Listing
April 2016

The cybernetics of TNF: Old views and newer ones.

Authors:
David Wallach

Semin Cell Dev Biol 2016 Feb 22;50:105-14. Epub 2015 Oct 22.

Department of Biological Chemistry, The Weizmann Institute of Science, 76100 Rehovot, Israel. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcdb.2015.10.014DOI Listing
February 2016

Activation of the NLRP3 inflammasome by proteins that signal for necroptosis.

Methods Enzymol 2014 ;545:67-81

Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot, Israel. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/B978-0-12-801430-1.00003-2DOI Listing
March 2015

The TNF family: only the surface has been scratched.

Authors:
David Wallach

Semin Immunol 2014 Jun 30;26(3):181-2. Epub 2014 Jun 30.

Department of Biological Chemistry, The Weizmann Institute of Science, 76100 Rehovot, Israel. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.smim.2014.06.002DOI Listing
June 2014

The in vivo significance of necroptosis: lessons from exploration of caspase-8 function.

Cytokine Growth Factor Rev 2014 Apr 24;25(2):157-65. Epub 2013 Dec 24.

Department of Biological Chemistry, The Weizmann Institute of Science, 76100 Rehovot, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cytogfr.2013.12.001DOI Listing
April 2014

Keeping inflammation at bay.

Elife 2014 Mar 25;3:e02583. Epub 2014 Mar 25.

David Wallach is an eLife reviewing editor, and is in the Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot, Israel

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963505PMC
http://dx.doi.org/10.7554/eLife.02583DOI Listing
March 2014

Concepts of tissue injury and cell death in inflammation: a historical perspective.

Nat Rev Immunol 2014 01 13;14(1):51-9. Epub 2013 Dec 13.

Department of Biological Chemistry, The Weizmann Institute of Science, 76100 Rehovot, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nri3561DOI Listing
January 2014

The TNF cytokine family: one track in a road paved by many.

Authors:
David Wallach

Cytokine 2013 Sep 20;63(3):225-9. Epub 2013 Jun 20.

Department of Biological Chemistry, The Weizmann Institute of Science, 76100 Rehovot, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cyto.2013.05.027DOI Listing
September 2013

How do cells sense foreign DNA? A new outlook on the function of STING.

Mol Cell 2013 Apr;50(1):1-2

Department of Biological Chemistry, The Weizmann Institute of Science, 76100 Rehovot, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molcel.2013.03.024DOI Listing
April 2013

Phosphorylation and dephosphorylation of the RIG-I-like receptors: a safety latch on a fateful pathway.

Immunity 2013 Mar;38(3):402-3

Department of Biological Chemistry, Weizmann Institute of Science, 76100 Rehovot, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2013.02.014DOI Listing
March 2013

Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome.

Immunity 2013 Jan 20;38(1):27-40. Epub 2012 Dec 20.

Department of Biological Chemistry, The Weizmann Institute of Science, 76100 Rehovot, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.immuni.2012.09.015DOI Listing
January 2013

'Necrosome'-induced inflammation: must cells die for it?

Trends Immunol 2011 Nov 2;32(11):505-9. Epub 2011 Sep 2.

Department of Biological Chemistry, The Weizmann Institute of Science, 76100 Rehovot, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.it.2011.07.004DOI Listing
November 2011

Anti-inflammatory functions of caspase-8.

Adv Exp Med Biol 2011 ;691:253-60

Department of Biological Chemistry, The Weizmann Institute of Science, 76100 Rehovot, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4419-6612-4_25DOI Listing
April 2011

Anti-inflammatory functions of the "apoptotic" caspases.

Ann N Y Acad Sci 2010 Oct;1209:17-22

Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot, Israel.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/j.1749-6632.2010.05742.x
Publisher Site
http://dx.doi.org/10.1111/j.1749-6632.2010.05742.xDOI Listing
October 2010

Intraoperative airway obstruction related to tracheostomy tube malposition in a patient with achondroplasia and Jeune's syndrome.

Middle East J Anaesthesiol 2010 Jun;20(5):735-8

Department of Anesthesiology, Stony Brook University Medical Center, New York, NY, USA.

View Article

Download full-text PDF

Source
June 2010

12th international TNF conference: the good, the bad and the scientists.

Cytokine Growth Factor Rev 2009 Aug 7;20(4):259-69. Epub 2009 Aug 7.

Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot 76100, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cytogfr.2009.07.008DOI Listing
August 2009

Caspase-8 is involved in neovascularization-promoting progenitor cell functions.

Arterioscler Thromb Vasc Biol 2009 Apr 2;29(4):571-8. Epub 2009 Jan 2.

Department of Internal Medicine III, University of Frankfurt, Frankfurt, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.108.182006DOI Listing
April 2009

Self-termination of the terminator.

Nat Immunol 2008 Dec;9(12):1325-7

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni1208-1325DOI Listing
December 2008

Cell-autonomous and non-cell-autonomous functions of caspase-8.

Cytokine Growth Factor Rev 2008 Jun-Aug;19(3-4):209-17

Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot, Israel.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S135961010800045
Publisher Site
http://dx.doi.org/10.1016/j.cytogfr.2008.04.012DOI Listing
September 2008

Subtrochanteric osteotomy effectively treats femoroacetabular impingement after slipped capital femoral epiphysis.

Clin Orthop Relat Res 2007 Nov;464:230-7

Department of Orthopaedics, The Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/BLO.0b013e3181586613DOI Listing
November 2007

Role of caspase-8 in hepatocyte response to infection and injury in mice.

Hepatology 2007 Apr;45(4):1014-24

Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.21495DOI Listing
April 2007

Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9.

Mol Cell Biol 2006 Nov 11;26(21):7880-91. Epub 2006 Sep 11.

Apoptosis Department and Centre for Genotoxic Stress, Institute for Cancer Biology, Danish Cancer Society, DK-2100 Copenhagen, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.00716-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636747PMC
November 2006

Hsp90 recognizes a common surface on client kinases.

J Biol Chem 2006 May 21;281(20):14361-9. Epub 2006 Mar 21.

Department of Biological Regulation, Weizmann Institute of Science, Rehovot 97100, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M512613200DOI Listing
May 2006

If the prophet does not come to the mountain: dynamics of signaling complexes in NF-kappaB activation.

Mol Cell 2006 May;22(4):433-6

Department of Biological Chemistry, The Weizmann Institute of Science, Rehovot, Israel.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S109727650600293
Publisher Site
http://dx.doi.org/10.1016/j.molcel.2006.05.002DOI Listing
May 2006

NF-kappaB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity.

J Immunol 2006 Apr;176(8):4666-74

Centro de Biología Molecular, Consejo Superior de Investigaciones Científicas, Universidad Autónoma de Madrid, Madrid, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.176.8.4666DOI Listing
April 2006

Caspase-8 promotes cell motility and calpain activity under nonapoptotic conditions.

Cancer Res 2006 Apr;66(8):4273-8

Mary Babb Randolph Cancer Center and Department of Biochemistry, West Virginia University, Morgantown, West Virginia 26506, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-05-4183DOI Listing
April 2006

Probing cell death by chemical screening.

Authors:
David Wallach

Nat Chem Biol 2005 Jul;1(2):68-9

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nchembio0705-68DOI Listing
July 2005

Potential complications of posterior spine fusion and instrumentation in patients with cerebral palsy treated with intrathecal baclofen infusion.

Spine (Phila Pa 1976) 2005 Apr;30(8):E219-24

Department of Orthopaedics and Rehabilitation, Box 850, The Milton S. Hershey Medical Center, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/01.brs.0000158869.90908.f8DOI Listing
April 2005

Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase.

Immunity 2004 Oct;21(4):477-89

Department of Biological Chemistry, The Weizmann Institute of Science, 76100 Rehovot, Israel.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S107476130400245
Publisher Site
http://dx.doi.org/10.1016/j.immuni.2004.08.009DOI Listing
October 2004

Purification of TNF binding proteins.

Methods Mol Med 2004 ;98:23-32

Institute of Immunology, Munich University, Munchen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1385/1-59259-771-8:023DOI Listing
April 2004

Slipped capital femoral epiphysis in a child with sickle cell disease.

Clin Orthop Relat Res 2004 Feb(419):198-201

Department of Orthopaedics and Rehabilitation, The Pennsylvania State University College of Medicine, Hershey, PA 17033, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/00003086-200402000-00032DOI Listing
February 2004

The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination.

Nature 2003 Aug;424(6950):801-5

Department of Biological Chemistry, The Weizmann Institute of Science, 76100 Rehovot, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature01802DOI Listing
August 2003

Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants.

Oncogene 2003 Aug;22(36):5667-76

Department of Molecular Cell Biology, Weizmann Institute of Science, PO Box 26, Rehovot, 76100, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.onc.1206724DOI Listing
August 2003

Hijacking of host cell IKK signalosomes by the transforming parasite Theileria.

Science 2002 Nov;298(5595):1033-6

Division of Molecular Pathology, Institute of Animal Pathology, University of Bern, CH-3012 Bern, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1075462DOI Listing
November 2002

Up the down staircase.

Authors:
David Wallach

Nat Immunol 2002 Sep;3(9):802-3

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ni0902-802DOI Listing
September 2002