Publications by authors named "David W Threadgill"

100Publications

Derivation of stable embryonic stem cell-like, but transcriptionally heterogenous, induced pluripotent stem cells from non-permissive mouse strains.

Mamm Genome 2020 Oct 4. Epub 2020 Oct 4.

Texas A&M Institute for Genome Sciences and Society, Texas A&M University, College Station, TX, 77843, USA.

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http://dx.doi.org/10.1007/s00335-020-09849-xDOI Listing
October 2020

Transcriptional Correlates of Tolerance and Lethality in Mice Predict Ebola Virus Disease Patient Outcomes.

Cell Rep 2020 02;30(6):1702-1713.e6

Center for Infection and Immunity, Columbia Mailman School of Public Health, New York, NY 10032, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.01.026DOI Listing
February 2020

and Other Zoonotic Pathogens in and Ticks Collected from the Chernobyl Exclusion Zone on the 30th Anniversary of the Nuclear Disaster.

Vector Borne Zoonotic Dis 2019 07 21;19(7):466-473. Epub 2019 May 21.

3 I.I. Schmalhausen Institute of Zoology of National Academy of Sciences of Ukraine, Kyiv, Ukraine.

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http://dx.doi.org/10.1089/vbz.2018.2318DOI Listing
July 2019

Gestational binge alcohol-induced alterations in maternal uterine artery transcriptome.

Reprod Toxicol 2019 08 9;87:42-49. Epub 2019 May 9.

Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.reprotox.2019.05.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6628922PMC
August 2019

Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse.

Chem Res Toxicol 2019 05 25;32(5):887-898. Epub 2019 Apr 25.

Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences , Texas A&M University , College Station , Texas 77843 , United States.

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http://pubs.acs.org/doi/10.1021/acs.chemrestox.9b00035
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http://dx.doi.org/10.1021/acs.chemrestox.9b00035DOI Listing
May 2019

New Zealand White Rabbits Effectively Clear Borrelia burgdorferi B31 despite the Bacterium's Functional Antigenic Variation System.

Infect Immun 2019 07 20;87(7). Epub 2019 Jun 20.

Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas, USA

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http://dx.doi.org/10.1128/IAI.00164-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6589054PMC
July 2019

Long-Term Combinatorial Exposure to Trichloroethylene and Inorganic Arsenic in Genetically Heterogeneous Mice Results in Renal Tubular Damage and Cancer-Associated Molecular Changes.

G3 (Bethesda) 2019 05 7;9(5):1729-1737. Epub 2019 May 7.

Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX 77843

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http://dx.doi.org/10.1534/g3.119.400161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6505147PMC
May 2019

Chronic exposure to e-cig aerosols during early development causes vascular dysfunction and offspring growth deficits.

Transl Res 2019 05 7;207:70-82. Epub 2019 Jan 7.

Department of Veterinary Physiology and Pharmacology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, Texas. Electronic address:

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http://dx.doi.org/10.1016/j.trsl.2019.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6486852PMC
May 2019

Characterizing Serpinb2 as a Modulator of TCDD-Induced Suppression of the B Cell.

Chem Res Toxicol 2018 11 30;31(11):1248-1259. Epub 2018 Oct 30.

Department of Biochemistry and Molecular Biology , Michigan State University , East Lansing , Michigan 48824 , United States.

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http://pubs.acs.org/doi/10.1021/acs.chemrestox.8b00225
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http://dx.doi.org/10.1021/acs.chemrestox.8b00225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7234800PMC
November 2018

gQTL: A Web Application for QTL Analysis Using the Collaborative Cross Mouse Genetic Reference Population.

G3 (Bethesda) 2018 07 31;8(8):2559-2562. Epub 2018 Jul 31.

Texas A&M Institute for Genome Sciences and Society

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http://dx.doi.org/10.1534/g3.118.200230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071593PMC
July 2018

A Whole Genome Assembly of the Horn Fly, , and Prediction of Genes with Roles in Metabolism and Sex Determination.

G3 (Bethesda) 2018 05 4;8(5):1675-1686. Epub 2018 May 4.

Texas A&M Institute for Genome Sciences and Society, Texas A&M University, College Station, Texas 77845.

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http://dx.doi.org/10.1534/g3.118.200154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940159PMC
May 2018

Tissue Level Diet and Sex-by-Diet Interactions Reveal Unique Metabolite and Clustering Profiles Using Untargeted Liquid Chromatography-Mass Spectrometry on Adipose, Skeletal Muscle, and Liver Tissue in C57BL6/J Mice.

J Proteome Res 2018 03 2;17(3):1077-1090. Epub 2018 Feb 2.

University of Tennessee-Knoxville , UT-ORNL Graduate School of Genome Science and Technology, Knoxville, Tennessee 37996, United States.

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http://dx.doi.org/10.1021/acs.jproteome.7b00750DOI Listing
March 2018

Population-based dose-response analysis of liver transcriptional response to trichloroethylene in mouse.

Mamm Genome 2018 Feb 20;29(1-2):168-181. Epub 2018 Jan 20.

Department of Veterinary Integrative Biosciences, Texas A&M University, 4458 TAMU, College Station, Texas, 77843, USA.

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http://dx.doi.org/10.1007/s00335-018-9734-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094947PMC
February 2018

Disruption of postnatal folliculogenesis and development of ovarian tumor in a mouse model with aberrant transforming growth factor beta signaling.

Reprod Biol Endocrinol 2017 Dec 8;15(1):94. Epub 2017 Dec 8.

Department of Veterinary Integrative Biosciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, 77843, USA.

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http://dx.doi.org/10.1186/s12958-017-0312-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5723096PMC
December 2017

Improving Metabolic Health Through Precision Dietetics in Mice.

Genetics 2018 01 20;208(1):399-417. Epub 2017 Nov 20.

Department of Molecular and Cellular Medicine, Texas A&M Health Science Center, Texas A&M University, College Station, Texas 77843

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http://dx.doi.org/10.1534/genetics.117.300536DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5753872PMC
January 2018

Host genetic background influences diverse neurological responses to viral infection in mice.

Sci Rep 2017 09 22;7(1):12194. Epub 2017 Sep 22.

Department of Veterinary Pathobiology, Texas A&M University, College Station, Texas, 77843, USA.

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http://dx.doi.org/10.1038/s41598-017-12477-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610195PMC
September 2017

Interdependency of EGF and GLP-2 Signaling in Attenuating Mucosal Atrophy in a Mouse Model of Parenteral Nutrition.

Cell Mol Gastroenterol Hepatol 2017 May 17;3(3):447-468. Epub 2017 Jan 17.

Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Colorado Medical School, Aurora, Colorado.

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http://dx.doi.org/10.1016/j.jcmgh.2016.12.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5403977PMC
May 2017

Prophylactic vaccination targeting ERBB3 decreases polyp burden in a mouse model of human colorectal cancer.

Oncoimmunology 2017 7;6(1):e1255395. Epub 2016 Dec 7.

Department of Veterinary Pathobiology, Department of Molecular and Cellular Medicine, Texas A&M University , College Station, TX, USA.

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http://dx.doi.org/10.1080/2162402X.2016.1255395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5283616PMC
December 2016

Impact of Nonalcoholic Fatty Liver Disease on Toxicokinetics of Tetrachloroethylene in Mice.

J Pharmacol Exp Ther 2017 04 1;361(1):17-28. Epub 2017 Feb 1.

Department of Veterinary Integrative Biosciences (J.A.C; S.F; Y.S.L; Y.I; W.C; I.R), Texas A&M Institute for Genome Sciences and Society (K.K; D.W.T; I.R), Department of Environmental and Occupational Health (T.J.M), and Department of Molecular and Cellular Medicine (D.W.T), Texas A&M University, College Station, Texas; and National Center for Toxicological Research, US FDA, Jefferson, Arkansas (I.P)

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http://dx.doi.org/10.1124/jpet.116.238790DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5363767PMC
April 2017

Hepatocyte ERBB3 and EGFR are required for maximal CCl4-induced liver fibrosis.

Am J Physiol Gastrointest Liver Physiol 2016 11 1;311(5):G807-G816. Epub 2016 Sep 1.

Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee.

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http://dx.doi.org/10.1152/ajpgi.00423.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130544PMC
November 2016

Loss of hepatocyte ERBB3 but not EGFR impairs hepatocarcinogenesis.

Am J Physiol Gastrointest Liver Physiol 2015 Dec 22;309(12):G942-54. Epub 2015 Oct 22.

Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee; Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee;

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http://dx.doi.org/10.1152/ajpgi.00089.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4683301PMC
December 2015

The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice.

Endocrinology 2016 Jan 20;157(1):220-32. Epub 2015 Oct 20.

Department of Veterans Affairs (A.C.P., M.G., R.M.B.), Tennessee Valley Health Authority, and Department of Medicine (R.M.B.), Division of Nephrology and Hypertension; Departments of Pharmacology (R.P.C., G.M., R.M.B.) and Cell and Developmental Biology (D.L., D.W.T., M.G.); Department of Medicine (M.F.M., G.P., A.C.P., M.G.), Division of Diabetes, Endocrinology, and Metabolism; and Departments of Molecular Physiology and Biophysics (B.A.C., A.C.P., O.P.G., M.G.) and Pathology, Microbiology, and Immunology (K.L.B.), Vanderbilt University Medical Center, Nashville, Tennessee 37232.

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http://dx.doi.org/10.1210/en.2015-1693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701878PMC
January 2016

A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.

PLoS Genet 2015 Feb 13;11(2):e1004850. Epub 2015 Feb 13.

Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America; Carolina Center for Genome Science, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.

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https://dx.plos.org/10.1371/journal.pgen.1004850
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http://dx.doi.org/10.1371/journal.pgen.1004850DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334553PMC
February 2015

ERBB3-independent activation of the PI3K pathway in EGFR-mutant lung adenocarcinomas.

Cancer Res 2015 Mar 16;75(6):1035-45. Epub 2015 Jan 16.

Department of Pathology and Yale Cancer Center, Yale University School of Medicine, New Haven, Connecticut. Program in Cancer Biology and Genetics, Memorial Sloan-Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-1625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4400867PMC
March 2015

Loss of hepatocyte EGFR has no effect alone but exacerbates carbon tetrachloride-induced liver injury and impairs regeneration in hepatocyte Met-deficient mice.

Am J Physiol Gastrointest Liver Physiol 2015 Mar 20;308(5):G364-77. Epub 2014 Nov 20.

Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, Tennessee; Digestive Disease Research Center, Vanderbilt University Medical Center, Nashville, Tennessee; Vanderbilt Diabetes Center, Vanderbilt University Medical Center, Nashville, Tennessee; Vanderbilt Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee;

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http://dx.doi.org/10.1152/ajpgi.00364.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346751PMC
March 2015

SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.

BMC Genomics 2014 Oct 3;15:847. Epub 2014 Oct 3.

Department of Genetics, University of North Carolina at Chapel Hill, CB 7295, Chapel Hill, NC 27599-7264, USA.

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http://dx.doi.org/10.1186/1471-2164-15-847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198738PMC
October 2014

Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response.

J Natl Cancer Inst 2013 Sep 29;105(18):1355-64. Epub 2013 Aug 29.

Affiliations of authors: Department of Genetics, North Carolina State University, Raleigh, NC (MCD, DWT); Department of Genetics (WKR) and Lineberger Cancer Center, University of North Carolina, Chapel Hill, NC (WKR, DWT).

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http://dx.doi.org/10.1093/jnci/djt226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776265PMC
September 2013

Mapping six new susceptibility to colon cancer (Scc) loci using a mouse interspecific backcross.

G3 (Bethesda) 2012 Dec 1;2(12):1577-84. Epub 2012 Dec 1.

Department of Genetics, Center for Gastrointestinal Biology and Disease, and Lineberger Cancer Center, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1534/g3.112.002253DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3516479PMC
December 2012

Status and access to the Collaborative Cross population.

Mamm Genome 2012 Oct 31;23(9-10):706-12. Epub 2012 Jul 31.

Department of Computer Science, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1007/s00335-012-9410-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463789PMC
October 2012

Efficacy of EGFR inhibition is modulated by model, sex, genetic background and diet: implications for preclinical cancer prevention and therapy trials.

PLoS One 2012 25;7(6):e39552. Epub 2012 Jun 25.

Department of Genetics, Curriculum in Genetics and Molecular Biology, Lineberger Cancer Center, Center for Gastrointestinal Biology and Disease, and Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0039552PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382564PMC
March 2013

Ten years of the collaborative cross.

G3 (Bethesda) 2012 Feb 1;2(2):153-6. Epub 2012 Feb 1.

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http://dx.doi.org/10.1534/g3.111.001891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284322PMC
February 2012

Ten years of the Collaborative Cross.

Genetics 2012 Feb;190(2):291-4

Department of Genetics, North Carolina State University, Raleigh, North Carolina 27695, USA.

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http://www.genetics.org/content/genetics/190/2/291.full.pdf
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http://www.genetics.org/cgi/doi/10.1534/genetics.111.138032
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http://dx.doi.org/10.1534/genetics.111.138032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276648PMC
February 2012

Dietary calcium supplementation enhances efficacy but also toxicity of EGFR inhibitor therapy for colon cancer.

Cancer Biol Ther 2012 Feb 1;13(3):130-7. Epub 2012 Feb 1.

Department of Genetics, Curriculum in Genetics and Molecular Biology, Lineberger Cancer Center and Center for Gastrointestinal Biology and Disease, University of North Carolina, Chapel Hill, NC, USA.

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http://dx.doi.org/10.4161/cbt.13.3.18690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336070PMC
February 2012

EGFR signaling promotes TGFβ-dependent renal fibrosis.

J Am Soc Nephrol 2012 Feb 17;23(2):215-24. Epub 2011 Nov 17.

Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1681/ASN.2011070645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269185PMC
February 2012

MicroRNA expression in the livers of inbred mice.

Mutat Res 2011 Sep 14;714(1-2):126-33. Epub 2011 May 14.

Department of Environmental Sciences & Engineering, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S002751071100116
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http://dx.doi.org/10.1016/j.mrfmmm.2011.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3166582PMC
September 2011

Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo.

J Bone Miner Res 2011 May;26(5):1022-34

Department of Orthopaedic Surgery, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://doi.wiley.com/10.1002/jbmr.295
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http://dx.doi.org/10.1002/jbmr.295DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179301PMC
May 2011

Architecture of energy balance traits in emerging lines of the Collaborative Cross.

Am J Physiol Endocrinol Metab 2011 Jun 22;300(6):E1124-34. Epub 2011 Mar 22.

Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1152/ajpendo.00707.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3118585PMC
June 2011

The collaborative cross: a recombinant inbred mouse population for the systems genetic era.

ILAR J 2011 ;52(1):24-31

Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.1093/ilar.52.1.24DOI Listing
July 2011

Epiregulin-dependent amphiregulin expression and ERBB2 signaling are involved in luteinizing hormone-induced paracrine signaling pathways in mouse ovary.

Biochem Biophys Res Commun 2011 Feb 13;405(2):319-24. Epub 2011 Jan 13.

Department of Life Science and Pharmaceutical Science, Ewha Womans University, Seoul, South Korea.

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X110005
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http://dx.doi.org/10.1016/j.bbrc.2011.01.039DOI Listing
February 2011

Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice.

Toxicol Sci 2011 Mar 6;120(1):206-17. Epub 2010 Dec 6.

Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1093/toxsci/kfq362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3044200PMC
March 2011

Genetic mapping and developmental timing of transmission ratio distortion in a mouse interspecific backcross.

BMC Genet 2010 Nov 3;11:98. Epub 2010 Nov 3.

Department of Genetics, Curriculum in Genetics and Molecular Biology, and Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1186/1471-2156-11-98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992037PMC
November 2010

Toxicogenetics: population-based testing of drug and chemical safety in mouse models.

Pharmacogenomics 2010 Aug;11(8):1127-36

Department of Environmental Sciences & Engineering, 0031 Michael Hooker Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

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http://dx.doi.org/10.2217/pgs.10.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3035927PMC
August 2010

Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice.

Environ Health Perspect 2010 May;118(5):596-601

Department of Genetics, Center for Environmental and Health Susceptibility, Lineberger Cancer Center, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1289/ehp.0901047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2866672PMC
May 2010

Dietary fat-dependent transcriptional architecture and copy number alterations associated with modifiers of mammary cancer metastasis.

Clin Exp Metastasis 2010 May 31;27(5):279-93. Epub 2010 Mar 31.

Department of Nutrition, University of North Carolina Chapel Hill, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1007/s10585-010-9326-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397665PMC
May 2010

Dietary fat alters pulmonary metastasis of mammary cancers through cancer autonomous and non-autonomous changes in gene expression.

Clin Exp Metastasis 2010 Feb 12;27(2):107-16. Epub 2010 Feb 12.

Department of Preventive Medicine, Mount Sinai School of Medicine, Box 1057, New York, NY 10029, USA.

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http://dx.doi.org/10.1007/s10585-009-9302-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6314014PMC
February 2010

Targeted inactivation of EGF receptor inhibits renal collecting duct development and function.

J Am Soc Nephrol 2010 Apr 4;21(4):573-8. Epub 2010 Feb 4.

Montreal Children's Hospital Research Institute and Department of Human Genetics, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1681/ASN.2009070719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844304PMC
April 2010

Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors.

Toxicol Sci 2010 May 29;115(1):131-9. Epub 2010 Jan 29.

Department of Environmental Sciences and Engineering, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1093/toxsci/kfq031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2855354PMC
May 2010

Deficient NRG1-ERBB signaling alters social approach: relevance to genetic mouse models of schizophrenia.

J Neurodev Disord 2009 Dec 27;1(4):302-12. Epub 2009 May 27.

Carolina Center for Developmental Disabilities, CB#7146, University of North Carolina School of Medicine, Chapel Hill, NC, 27599, USA,

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http://jneurodevdisorders.biomedcentral.com/articles/10.1007
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http://dx.doi.org/10.1007/s11689-009-9017-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164004PMC
December 2009

Dietary fat alters body composition, mammary development, and cytochrome p450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors.

Environ Health Perspect 2009 Sep 18;117(9):1414-9. Epub 2009 May 18.

Department of Genetics, Center for Environmental Health and Susceptibility, University of North Carolina at Chapel Hill, Chapel Hill, NC 27695, USA.

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http://dx.doi.org/10.1289/ehp.0800530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737019PMC
September 2009

Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium.

J Clin Invest 2009 Sep 17;119(9):2702-13. Epub 2009 Aug 17.

Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://www.jci.org/articles/view/36435
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http://dx.doi.org/10.1172/JCI36435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2735918PMC
September 2009

The gastrointestinal microbiome: a malleable, third genome of mammals.

Mamm Genome 2009 Jul 21;20(7):395-403. Epub 2009 Jul 21.

Department of Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1007/s00335-009-9204-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4372805PMC
July 2009

Replication and narrowing of gene expression quantitative trait loci using inbred mice.

Mamm Genome 2009 Jul 17;20(7):437-46. Epub 2009 Jul 17.

Department of Environmental Sciences & Engineering, University of North Carolina, CB 7431, Chapel Hill, NC 27599, USA.

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http://link.springer.com/10.1007/s00335-009-9199-0
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http://dx.doi.org/10.1007/s00335-009-9199-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745627PMC
July 2009

Parent-of-origin effects on cardiac response to pressure overload in mice.

Am J Physiol Heart Circ Physiol 2009 Sep 26;297(3):H1003-9. Epub 2009 Jun 26.

Curriculum in Toxicology, Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1152/ajpheart.00896.2008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2755989PMC
September 2009

Placental overgrowth and fertility defects in mice with a hypermorphic allele of epidermal growth factor receptor.

Mamm Genome 2009 Jun 23;20(6):339-49. Epub 2009 May 23.

Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1007/s00335-009-9189-2DOI Listing
June 2009

Murine models of colorectal cancer.

Mamm Genome 2009 May 15;20(5):261-8. Epub 2009 May 15.

Curriculum in Genetics and Molecular Biology, Department of Genetics, Lineberger Cancer Center and Center for Gastrointestinal Biology and Disease, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1007/s00335-009-9186-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2819073PMC
May 2009

Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel.

Toxicol Sci 2009 Jul 6;110(1):235-43. Epub 2009 May 6.

Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1093/toxsci/kfp096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696330PMC
July 2009

Modeling cancer patient populations in mice: complex genetic and environmental factors.

Drug Discov Today Dis Models 2008 ;4(2):83-88

Department of Pharmacology and Cancer Biology, Molecular Cancer Biology Program, and Integrated Toxicology and Environmental Health Program, Duke University, Durham, NC 27710 USA.

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http://dx.doi.org/10.1016/j.ddmod.2007.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2516949PMC
January 2008

Generation and validation of mice carrying a conditional allele of the epidermal growth factor receptor.

Genesis 2009 Feb;47(2):85-92

Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1002/dvg.20464DOI Listing
February 2009