David W Silversides

David W Silversides

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David W Silversides

David W Silversides

Publications by authors named "David W Silversides"

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Dysregulation of cotranscriptional alternative splicing underlies CHARGE syndrome.

Proc Natl Acad Sci U S A 2018 01 8;115(4):E620-E629. Epub 2018 Jan 8.

Molecular Genetics of Development Laboratory, Department of Biological Sciences, University of Quebec at Montreal, Montreal, QC H2X 3Y7, Canada;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1715378115
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http://dx.doi.org/10.1073/pnas.1715378115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789929PMC
January 2018

Upregulation of the Nr2f1-A830082K12Rik gene pair in murine neural crest cells results in a complex phenotype reminiscent of Waardenburg syndrome type 4.

Dis Model Mech 2016 11 1;9(11):1283-1293. Epub 2016 Sep 1.

Molecular Genetics of Development Laboratory, Department of Biological Sciences and BioMed Research Center, University of Quebec at Montreal (UQAM), Montreal, H2X 3Y7, Canada

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http://dx.doi.org/10.1242/dmm.026773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5117235PMC
November 2016

Differential regulation of Janus kinase 3 (JAK3) in bovine preovulatory follicles and identification of JAK3 interacting proteins in granulosa cells.

J Ovarian Res 2016 Oct 28;9(1):71. Epub 2016 Oct 28.

Département de biomédecine vétérinaire, Faculté de médecine vétérinaire, Centre de recherche en reproduction animale (CRRA), Université de Montréal, P.O. Box 5000, St-Hyacinthe, Québec, J2S 7C6, Canada.

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http://dx.doi.org/10.1186/s13048-016-0280-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5086056PMC
October 2016

Male-biased aganglionic megacolon in the TashT mouse line due to perturbation of silencer elements in a large gene desert of chromosome 10.

PLoS Genet 2015 Mar 18;11(3):e1005093. Epub 2015 Mar 18.

Molecular Genetics of Development Laboratory, Department of Biological Sciences and BioMed Research Center, University of Quebec at Montreal (UQAM), Quebec, Canada.

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http://dx.doi.org/10.1371/journal.pgen.1005093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364714PMC
March 2015

Differential expression of lysosome-associated protein transmembrane-4 beta (LAPTM4B) in granulosa cells of ovarian follicles and in other bovine tissues.

J Ovarian Res 2015 Mar 26;8:12. Epub 2015 Mar 26.

Centre de recherche en reproduction animale, Département de biomédecine vétérinaire, Faculté de médecine vétérinaire, Université de Montréal, P.O. Box 5000, St-Hyacinthe, Québec, J2S 7C6, Canada.

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http://dx.doi.org/10.1186/s13048-015-0148-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4387681PMC
March 2015

Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice.

Endocrinology 2013 Dec 8;154(12):4746-56. Epub 2013 Oct 8.

Institut de Recherches Cliniques de Montréal, 110 Pine Avenue West, Montréal, Québec, Canada H2W 1R7.

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http://dx.doi.org/10.1210/en.2013-1699DOI Listing
December 2013

Transgenic mouse analysis of Sry expression during the pre- and peri-implantation stage.

Dev Dyn 2012 Jul 18;241(7):1192-204. Epub 2012 May 18.

Department of Veterinary Biomedicine, Centre de Recherche en Reproduction Animale, Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, QC, Canada.

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http://dx.doi.org/10.1002/dvdy.23798DOI Listing
July 2012

Disorder of sex development (XX male, SRY negative) in a French bulldog.

Can Vet J 2011 Jun;52(6):670-2

Department of Veterinary Biomedicine, Faculty of Veterinary Medicine, University of Montreal, 3200 Sicotte, CP 5000, St-Hyacinthe, Quebec J2S 7C6, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3095171PMC
June 2011

Protein-protein interactions monitored in cells from transgenic mice using bioluminescence resonance energy transfer.

FASEB J 2010 Aug 24;24(8):2829-38. Epub 2010 Mar 24.

Department of Biochemistry, Institute for Research in Immunology and Cancer, and Groupe de Recherche Universitaire sur le Médicament, Université de Montréal, Montréal, Québec, Canada.

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http://www.fasebj.org/doi/10.1096/fj.09-144816
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http://dx.doi.org/10.1096/fj.09-144816DOI Listing
August 2010

Conserved usage of alternative 5' untranslated exons of the GATA4 gene.

PLoS One 2009 Dec 24;4(12):e8454. Epub 2009 Dec 24.

Reproduction, Perinatal and Child Health, Centre de Recherche du Centre Hospitalier Universitaire de Québec, Quebec City, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0008454PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2795200PMC
December 2009

Chronic increases in circulating prorenin are not associated with renal or cardiac pathologies.

Hypertension 2009 Jun 13;53(6):1062-9. Epub 2009 Apr 13.

Department of Medicine, Laboratory of Molecular Biochemistry of Hypertension, Clinical Research Institute of Montreal, University of Montreal, Montreal, Quebec, Canada

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http://jra.sagepub.com/content/9/1_suppl/S4.1.full.pdf
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http://hyper.ahajournals.org/cgi/doi/10.1161/HYPERTENSIONAHA
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http://dx.doi.org/10.1161/HYPERTENSIONAHA.108.115444DOI Listing
June 2009

Cytokine expression by peripheral blood neutrophils from heaves-affected horses before and after allergen challenge.

Vet J 2008 Nov 14;178(2):227-32. Epub 2007 Sep 14.

Université de Montréal, Faculté de Médecine Vétérinaire, Département de Sciences Cliniques, C.P. 5000, St-Hyacinthe, Québec, Canada J2S 7C6.

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http://dx.doi.org/10.1016/j.tvjl.2007.07.027DOI Listing
November 2008

Novel pre- and post-gastrulation expression of Gata4 within cells of the inner cell mass and migratory neural crest cells.

Dev Dyn 2008 Apr;237(4):1133-43

Department of Veterinary Biomedicine, Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, QC, Canada.

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http://dx.doi.org/10.1002/dvdy.21496DOI Listing
April 2008

A GATA4/WT1 cooperation regulates transcription of genes required for mammalian sex determination and differentiation.

BMC Mol Biol 2008 Apr 29;9:44. Epub 2008 Apr 29.

Ontogeny-Reproduction Research Unit, Centre de Recherche du Centre Hospitalier Universitaire de Quebec (CRCHUQ), Quebec City, QC, G1V 4G2, Canada.

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http://dx.doi.org/10.1186/1471-2199-9-44DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2387164PMC
April 2008

Presumptive pre-Sertoli cells express genes involved in cell proliferation and cell signalling during a critical window in early testis differentiation.

Mol Reprod Dev 2007 Dec;74(12):1491-504

Faculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, Quebec, Canada.

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http://dx.doi.org/10.1002/mrd.20722DOI Listing
December 2007

Structure of the bovine VASAP-60/PRKCSH gene, functional analysis of the promoter, and gene expression analysis.

Gene 2007 Apr 22;391(1-2):63-75. Epub 2006 Dec 22.

Centre de Recherche en Reproduction Animale, Faculté de Médecine Vétérinaire, Université de Montréal, P.O. Box 5000, St-Hyacinthe, Québec, Canada J2S 7C6.

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http://dx.doi.org/10.1016/j.gene.2006.12.012DOI Listing
April 2007

Low-density lipoprotein receptor-related protein 8 (LRP8) is upregulated in granulosa cells of bovine dominant follicle: molecular characterization and spatio-temporal expression studies.

Biol Reprod 2007 Mar 15;76(3):466-75. Epub 2006 Nov 15.

Centre de Recherche en Reproduction Animale, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, Québec, Canada J2S 7C6.

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https://academic.oup.com/biolreprod/article-lookup/doi/10.10
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http://dx.doi.org/10.1095/biolreprod.106.057216DOI Listing
March 2007

The proximal Gata4 promoter directs reporter gene expression to sertoli cells during mouse gonadal development.

Biol Reprod 2007 Jan 4;76(1):85-95. Epub 2006 Oct 4.

Ontogeny-Reproduction Research Unit, Centre de Recherche du Centre Hospitalier Universitaire de Québec, Centre de Recherche en Biologie de la Reproduction, Department of Obstetrics and Gynecology, Laval University, Québec City, Québec, Canada G1K 7P4.

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http://dx.doi.org/10.1095/biolreprod.106.055137DOI Listing
January 2007

Induction of alpha-caveolin-1 (alphaCAV1) expression in bovine granulosa cells in response to an ovulatory dose of human chorionic gonadotropin.

Mol Reprod Dev 2006 Nov;73(11):1353-60

Centre de Recherche en Reproduction Animale, Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, Québec, Canada.

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http://doi.wiley.com/10.1002/mrd.20513
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http://dx.doi.org/10.1002/mrd.20513DOI Listing
November 2006

Expression of phospholipase A2 group IVA (PLA2G4A) is upregulated by human chorionic gonadotropin in bovine granulosa cells of ovulatory follicles.

Biol Reprod 2006 Jun 1;74(6):1096-103. Epub 2006 Mar 1.

Centre de recherche en reproduction animale, Faculté de médecine vétérinaire, Université de Montréal, St-Hyacinthe, Québec, Canada J2S 7C6.

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http://dx.doi.org/10.1095/biolreprod.105.048579DOI Listing
June 2006

Human and pig SRY 5' flanking sequences can direct reporter transgene expression to the genital ridge and to migrating neural crest cells.

Dev Dyn 2006 Mar;235(3):623-32

Faculty of Veterinary Medicine, University of Montreal, Saint-Hyacinthe, Quebec, Canada.

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http://dx.doi.org/10.1002/dvdy.20670DOI Listing
March 2006

Identification of downregulated messenger RNAs in bovine granulosa cells of dominant follicles following stimulation with human chorionic gonadotropin.

Biol Reprod 2005 Aug 13;73(2):324-33. Epub 2005 Apr 13.

Centre de recherche en reproduction animale, Faculté de médecine vétérinaire, Université de Montréal, St-Hyacinthe, Québec, Canada J2S 7C6.

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http://dx.doi.org/10.1095/biolreprod.104.038026DOI Listing
August 2005

New insights into the regulation of mammalian sex determination and male sex differentiation.

Vitam Horm 2005 ;70:387-413

Ontogeny-Reproduction Research Unit, CHUL Research Centre, Department of Obstetrics and Gynecology, Faculty of Medicine, Laval University, Ste-Foy, Québec G1V 4G2, Canada.

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http://dx.doi.org/10.1016/S0083-6729(05)70013-3DOI Listing
June 2005

Pre-sertoli specific gene expression profiling reveals differential expression of Ppt1 and Brd3 genes within the mouse genital ridge at the time of sex determination.

Biol Reprod 2004 Sep 5;71(3):820-7. Epub 2004 May 5.

Centre de recherche en reproduction animale, Faculté de médecin vétérinaire, Université de Montréal, St.-Hyacinthe, Québec J2S 7C6, Canada.

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http://dx.doi.org/10.1095/biolreprod.104.029371DOI Listing
September 2004

Chronic production of angiotensin IV in the brain leads to hypertension that is reversible with an angiotensin II AT1 receptor antagonist.

Circ Res 2004 Jun 29;94(11):1451-7. Epub 2004 Apr 29.

Laboratories of Molecular Biochemistry of Hypertension, Clinical Research Institute of Montreal, Quebec, Canada.

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http://dx.doi.org/10.1161/01.RES.0000130654.56599.40DOI Listing
June 2004

Gene expression profiling of differentially expressed genes in granulosa cells of bovine dominant follicles using suppression subtractive hybridization.

Biol Reprod 2004 Feb 20;70(2):523-33. Epub 2003 Oct 20.

Centre de recherche en reproduction animale, Faculté de médecine vétérinaire, Université de Montréal, St-Hyacinthe, Québec, J2S 7C6, Canada.

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http://dx.doi.org/10.1095/biolreprod.103.021709DOI Listing
February 2004

Immunolocalization of vacuolar system-associated protein-60 (VASAP-60).

Histochem Cell Biol 2003 May 15;119(5):371-81. Epub 2003 May 15.

Centre de recherche en reproduction animale, Faculté de médecine vétérinaire, Université de Montréal, St-Hyacinthe, Québec, Canada.

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http://dx.doi.org/10.1007/s00418-003-0521-8DOI Listing
May 2003

Porcine SRY promoter is a target for steroidogenic factor 1.

Biol Reprod 2003 Apr 31;68(4):1098-106. Epub 2002 Oct 31.

Centre de recherche en reproduction animale, Department of Veterinary Biomedicine, Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, Québec, Canada J2S 7C6.

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http://dx.doi.org/10.1095/biolreprod.102.010884DOI Listing
April 2003

Serine protease inhibitor-E2 (SERPINE2) is differentially expressed in granulosa cells of dominant follicle in cattle.

Mol Reprod Dev 2003 Feb;64(2):152-65

Centre de recherche en reproduction animale, Faculté de médecine vétérinaire, Université de Montréal, St-Hyacinthe, Québec, Canada.

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http://dx.doi.org/10.1002/mrd.10239DOI Listing
February 2003

Brain-specific restoration of angiotensin II corrects renal defects seen in angiotensinogen-deficient mice.

J Biol Chem 2003 Jan 23;278(4):2184-9. Epub 2002 Oct 23.

Laboratory of Molecular Biochemistry of Hypertension, Clinical Research Institute of Montreal, Quebec H2W 1R7, Canada.

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http://www.jbc.org/content/278/4/2184.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M209933200
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http://dx.doi.org/10.1074/jbc.M209933200DOI Listing
January 2003

Conservation of the function of DMRT1 regulatory sequences in mammalian sex differentiation.

Genesis 2002 Dec;34(4):236-43

Faculty of Veterinary Medicine, University of Montreal, St-Hyacinthe, Québec, Canada.

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http://doi.wiley.com/10.1002/gene.10158
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http://dx.doi.org/10.1002/gene.10158DOI Listing
December 2002

The porcine SRY promoter is transactivated within a male genital ridge environment.

Genesis 2002 Aug;33(4):170-80

Faculty of Veterinary Medicine, University of Montreal, Saint Hyacinthe, Québec, Canada.

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http://dx.doi.org/10.1002/gene.10106DOI Listing
August 2002

Tissue activity of circulating prorenin.

Am J Hypertens 2002 Mar;15(3):280-5

Laboratory of Molecular Biochemistry of Hypertension, Clinical Research Institute of Montreal, CRRA, St Hyacinthe, Quebec, Canada.

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http://dx.doi.org/10.1016/s0895-7061(01)02284-1DOI Listing
March 2002