David W Fardo

David W Fardo

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David W Fardo

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Evaluation of CD33 as a genetic risk factor for Alzheimer's disease.

Acta Neuropathol 2019 Aug 4;138(2):187-199. Epub 2019 Apr 4.

Department of Biostatistics and Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.

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http://dx.doi.org/10.1007/s00401-019-02000-4DOI Listing
August 2019

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 Aug 15. Epub 2019 Aug 15.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0495-7DOI Listing
August 2019

Tau and TDP-43 proteinopathies: kindred pathologic cascades and genetic pleiotropy.

Lab Invest 2019 Jul 11;99(7):993-1007. Epub 2019 Feb 11.

University of Kentucky College of Medicine, Lexington, KY, USA.

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http://dx.doi.org/10.1038/s41374-019-0196-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609463PMC
July 2019

TDP-43 proteinopathy in aging: Associations with risk-associated gene variants and with brain parenchymal thyroid hormone levels.

Neurobiol Dis 2019 05 23;125:67-76. Epub 2019 Jan 23.

Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA; Department of Biostatistics, University of Kentucky, Lexington, KY, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S09699961183070
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http://dx.doi.org/10.1016/j.nbd.2019.01.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696921PMC
May 2019

Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing.

Authors:
Brian W Kunkle Benjamin Grenier-Boley Rebecca Sims Joshua C Bis Vincent Damotte Adam C Naj Anne Boland Maria Vronskaya Sven J van der Lee Alexandre Amlie-Wolf Céline Bellenguez Aura Frizatti Vincent Chouraki Eden R Martin Kristel Sleegers Nandini Badarinarayan Johanna Jakobsdottir Kara L Hamilton-Nelson Sonia Moreno-Grau Robert Olaso Rachel Raybould Yuning Chen Amanda B Kuzma Mikko Hiltunen Taniesha Morgan Shahzad Ahmad Badri N Vardarajan Jacques Epelbaum Per Hoffmann Merce Boada Gary W Beecham Jean-Guillaume Garnier Denise Harold Annette L Fitzpatrick Otto Valladares Marie-Laure Moutet Amy Gerrish Albert V Smith Liming Qu Delphine Bacq Nicola Denning Xueqiu Jian Yi Zhao Maria Del Zompo Nick C Fox Seung-Hoan Choi Ignacio Mateo Joseph T Hughes Hieab H Adams John Malamon Florentino Sanchez-Garcia Yogen Patel Jennifer A Brody Beth A Dombroski Maria Candida Deniz Naranjo Makrina Daniilidou Gudny Eiriksdottir Shubhabrata Mukherjee David Wallon James Uphill Thor Aspelund Laura B Cantwell Fabienne Garzia Daniela Galimberti Edith Hofer Mariusz Butkiewicz Bertrand Fin Elio Scarpini Chloe Sarnowski Will S Bush Stéphane Meslage Johannes Kornhuber Charles C White Yuenjoo Song Robert C Barber Sebastiaan Engelborghs Sabrina Sordon Dina Voijnovic Perrie M Adams Rik Vandenberghe Manuel Mayhaus L Adrienne Cupples Marilyn S Albert Peter P De Deyn Wei Gu Jayanadra J Himali Duane Beekly Alessio Squassina Annette M Hartmann Adelina Orellana Deborah Blacker Eloy Rodriguez-Rodriguez Simon Lovestone Melissa E Garcia Rachelle S Doody Carmen Munoz-Fernadez Rebecca Sussams Honghuang Lin Thomas J Fairchild Yolanda A Benito Clive Holmes Hata Karamujić-Čomić Matthew P Frosch Hakan Thonberg Wolfgang Maier Gennady Roshchupkin Bernardino Ghetti Vilmantas Giedraitis Amit Kawalia Shuo Li Ryan M Huebinger Lena Kilander Susanne Moebus Isabel Hernández M Ilyas Kamboh RoseMarie Brundin James Turton Qiong Yang Mindy J Katz Letizia Concari Jenny Lord Alexa S Beiser C Dirk Keene Seppo Helisalmi Iwona Kloszewska Walter A Kukull Anne Maria Koivisto Aoibhinn Lynch Lluís Tarraga Eric B Larson Annakaisa Haapasalo Brian Lawlor Thomas H Mosley Richard B Lipton Vincenzo Solfrizzi Michael Gill W T Longstreth Thomas J Montine Vincenza Frisardi Monica Diez-Fairen Fernando Rivadeneira Ronald C Petersen Vincent Deramecourt Ignacio Alvarez Francesca Salani Antonio Ciaramella Eric Boerwinkle Eric M Reiman Nathalie Fievet Jerome I Rotter Joan S Reisch Olivier Hanon Chiara Cupidi A G Andre Uitterlinden Donald R Royall Carole Dufouil Raffaele Giovanni Maletta Itziar de Rojas Mary Sano Alexis Brice Roberta Cecchetti Peter St George-Hyslop Karen Ritchie Magda Tsolaki Debby W Tsuang Bruno Dubois David Craig Chuang-Kuo Wu Hilkka Soininen Despoina Avramidou Roger L Albin Laura Fratiglioni Antonia Germanou Liana G Apostolova Lina Keller Maria Koutroumani Steven E Arnold Francesco Panza Olymbia Gkatzima Sanjay Asthana Didier Hannequin Patrice Whitehead Craig S Atwood Paolo Caffarra Harald Hampel Inés Quintela Ángel Carracedo Lars Lannfelt David C Rubinsztein Lisa L Barnes Florence Pasquier Lutz Frölich Sandra Barral Bernadette McGuinness Thomas G Beach Janet A Johnston James T Becker Peter Passmore Eileen H Bigio Jonathan M Schott Thomas D Bird Jason D Warren Bradley F Boeve Michelle K Lupton James D Bowen Petra Proitsi Adam Boxer John F Powell James R Burke John S K Kauwe Jeffrey M Burns Michelangelo Mancuso Joseph D Buxbaum Ubaldo Bonuccelli Nigel J Cairns Andrew McQuillin Chuanhai Cao Gill Livingston Chris S Carlson Nicholas J Bass Cynthia M Carlsson John Hardy Regina M Carney Jose Bras Minerva M Carrasquillo Rita Guerreiro Mariet Allen Helena C Chui Elizabeth Fisher Carlo Masullo Elizabeth A Crocco Charles DeCarli Gina Bisceglio Malcolm Dick Li Ma Ranjan Duara Neill R Graff-Radford Denis A Evans Angela Hodges Kelley M Faber Martin Scherer Kenneth B Fallon Matthias Riemenschneider David W Fardo Reinhard Heun Martin R Farlow Heike Kölsch Steven Ferris Markus Leber Tatiana M Foroud Isabella Heuser Douglas R Galasko Ina Giegling Marla Gearing Michael Hüll Daniel H Geschwind John R Gilbert John Morris Robert C Green Kevin Mayo John H Growdon Thomas Feulner Ronald L Hamilton Lindy E Harrell Dmitriy Drichel Lawrence S Honig Thomas D Cushion Matthew J Huentelman Paul Hollingworth Christine M Hulette Bradley T Hyman Rachel Marshall Gail P Jarvik Alun Meggy Erin Abner Georgina E Menzies Lee-Way Jin Ganna Leonenko Luis M Real Gyungah R Jun Clinton T Baldwin Detelina Grozeva Anna Karydas Giancarlo Russo Jeffrey A Kaye Ronald Kim Frank Jessen Neil W Kowall Bruno Vellas Joel H Kramer Emma Vardy Frank M LaFerla Karl-Heinz Jöckel James J Lah Martin Dichgans James B Leverenz David Mann Allan I Levey Stuart Pickering-Brown Andrew P Lieberman Norman Klopp Kathryn L Lunetta H-Erich Wichmann Constantine G Lyketsos Kevin Morgan Daniel C Marson Kristelle Brown Frank Martiniuk Christopher Medway Deborah C Mash Markus M Nöthen Eliezer Masliah Nigel M Hooper Wayne C McCormick Antonio Daniele Susan M McCurry Anthony Bayer Andrew N McDavid John Gallacher Ann C McKee Hendrik van den Bussche Marsel Mesulam Carol Brayne Bruce L Miller Steffi Riedel-Heller Carol A Miller Joshua W Miller Ammar Al-Chalabi John C Morris Christopher E Shaw Amanda J Myers Jens Wiltfang Sid O'Bryant John M Olichney Victoria Alvarez Joseph E Parisi Andrew B Singleton Henry L Paulson John Collinge William R Perry Simon Mead Elaine Peskind David H Cribbs Martin Rossor Aimee Pierce Natalie S Ryan Wayne W Poon Benedetta Nacmias Huntington Potter Sandro Sorbi Joseph F Quinn Eleonora Sacchinelli Ashok Raj Gianfranco Spalletta Murray Raskind Carlo Caltagirone Paola Bossù Maria Donata Orfei Barry Reisberg Robert Clarke Christiane Reitz A David Smith John M Ringman Donald Warden Erik D Roberson Gordon Wilcock Ekaterina Rogaeva Amalia Cecilia Bruni Howard J Rosen Maura Gallo Roger N Rosenberg Yoav Ben-Shlomo Mark A Sager Patrizia Mecocci Andrew J Saykin Pau Pastor Michael L Cuccaro Jeffery M Vance Julie A Schneider Lori S Schneider Susan Slifer William W Seeley Amanda G Smith Joshua A Sonnen Salvatore Spina Robert A Stern Russell H Swerdlow Mitchell Tang Rudolph E Tanzi John Q Trojanowski Juan C Troncoso Vivianna M Van Deerlin Linda J Van Eldik Harry V Vinters Jean Paul Vonsattel Sandra Weintraub Kathleen A Welsh-Bohmer Kirk C Wilhelmsen Jennifer Williamson Thomas S Wingo Randall L Woltjer Clinton B Wright Chang-En Yu Lei Yu Yasaman Saba Alberto Pilotto Maria J Bullido Oliver Peters Paul K Crane David Bennett Paola Bosco Eliecer Coto Virginia Boccardi Phil L De Jager Alberto Lleo Nick Warner Oscar L Lopez Martin Ingelsson Panagiotis Deloukas Carlos Cruchaga Caroline Graff Rhian Gwilliam Myriam Fornage Alison M Goate Pascual Sanchez-Juan Patrick G Kehoe Najaf Amin Nilifur Ertekin-Taner Claudine Berr Stéphanie Debette Seth Love Lenore J Launer Steven G Younkin Jean-Francois Dartigues Chris Corcoran M Arfan Ikram Dennis W Dickson Gael Nicolas Dominique Campion JoAnn Tschanz Helena Schmidt Hakon Hakonarson Jordi Clarimon Ron Munger Reinhold Schmidt Lindsay A Farrer Christine Van Broeckhoven Michael C O'Donovan Anita L DeStefano Lesley Jones Jonathan L Haines Jean-Francois Deleuze Michael J Owen Vilmundur Gudnason Richard Mayeux Valentina Escott-Price Bruce M Psaty Alfredo Ramirez Li-San Wang Agustin Ruiz Cornelia M van Duijn Peter A Holmans Sudha Seshadri Julie Williams Phillippe Amouyel Gerard D Schellenberg Jean-Charles Lambert Margaret A Pericak-Vance

Nat Genet 2019 03 28;51(3):414-430. Epub 2019 Feb 28.

John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1038/s41588-019-0358-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463297PMC
March 2019

Socioemotional selectivity and psychological health in amyotrophic lateral sclerosis patients and caregivers: a longitudinal, dyadic analysis.

Psychol Health 2019 Mar 23:1-17. Epub 2019 Mar 23.

c Department of Biostatistics, College of Public Health , University of Kentucky , Lexington , KY , USA.

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http://dx.doi.org/10.1080/08870446.2019.1587441DOI Listing
March 2019

Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs.

Neurobiol Aging 2019 02 23;74:135-146. Epub 2018 Oct 23.

Department of Biostatistics, University of Kentucky, Lexington, KY, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2018.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6331247PMC
February 2019

Patterns and predictors of chronic opioid use in older adults: A retrospective cohort study.

PLoS One 2019 11;14(1):e0210341. Epub 2019 Jan 11.

Department of Epidemiology, University of Kentucky, Lexington, Kentucky, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0210341PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329525PMC
January 2019

Tobacco Smoking and Dementia in a Kentucky Cohort: A Competing Risk Analysis.

J Alzheimers Dis 2019 ;68(2):625-633

Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA.

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https://www.medra.org/servlet/aliasResolver?alias=iospress&a
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http://dx.doi.org/10.3233/JAD-181119DOI Listing
January 2019

Principals about principal components in statistical genetics.

Brief Bioinform 2018 Sep 14. Epub 2018 Sep 14.

University of Liège working on Systems Genetics.

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http://dx.doi.org/10.1093/bib/bby081DOI Listing
September 2018

Longitudinal data methods for evaluating genome-by-epigenome interactions in families.

BMC Genet 2018 09 17;19(Suppl 1):82. Epub 2018 Sep 17.

Department of Biostatistics, College of Public Health, University of Kentucky, 725 Rose St, Lexington, KY, 40536, USA.

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http://dx.doi.org/10.1186/s12863-018-0642-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156905PMC
September 2018

Association analyses of repeated measures on triglyceride and high-density lipoprotein levels: insights from GAW20.

BMC Genet 2018 09 17;19(Suppl 1):73. Epub 2018 Sep 17.

Department of Biostatistics, University of Kentucky, 111 Washington Ave, Lexington, KY, 40536, USA.

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http://dx.doi.org/10.1186/s12863-018-0651-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157164PMC
September 2018

Genetic Comparison of Symptomatic and Asymptomatic Persons With Alzheimer Disease Neuropathology.

Alzheimer Dis Assoc Disord 2017 Jul-Sep;31(3):232-238

*Department of Biostatistics †National Alzheimer's Coordinating Center, University of Washington, Seattle, WA ‡Department of Biostatistics, University of Kentucky, Lexington, KY §Dept. of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY ∥Department of Neurology, Knight Alzheimer's Disease Research Center, Washington University School of Medicine, St. Louis, MI.

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http://dx.doi.org/10.1097/WAD.0000000000000179DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5432419PMC
May 2018

Overlapping but distinct TDP-43 and tau pathologic patterns in aged hippocampi.

Brain Pathol 2018 03 24;28(2):264-273. Epub 2017 Mar 24.

Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, KY.

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http://dx.doi.org/10.1111/bpa.12505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5591757PMC
March 2018

The Amygdala as a Locus of Pathologic Misfolding in Neurodegenerative Diseases.

J Neuropathol Exp Neurol 2018 Jan;77(1):2-20

Division of Neuropathology; Sanders-Brown Center on Aging; Department of Pathology; Department of Epidemiology; Department of Physiology; Department of Statistics; Department of Neurology; Department of Neuroscience; Department of Molecular and Cellular Biochemistry; Department of Biostatistics, University of Kentucky, Lexington, Kentucky; and Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, Texas.

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http://dx.doi.org/10.1093/jnen/nlx099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901077PMC
January 2018

Detergent Insoluble Proteins and Inclusion Body-Like Structures Immunoreactive for PRKDC/DNA-PK/DNA-PKcs, FTL, NNT, and AIFM1 in the Amygdala of Cognitively Impaired Elderly Persons.

J Neuropathol Exp Neurol 2018 Jan;77(1):21-39

Department of Molecular and Cellular Biochemistry; Department of Biostatistics; Sanders-Brown Center on Aging; Department of Pathology, University of Kentucky, Lexington, Kentucky; and Research and Development, Lexington VA Medical Center, Lexington, Kentucky.

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http://dx.doi.org/10.1093/jnen/nlx097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251632PMC
January 2018

Peripheral Inflammation, Apolipoprotein E4, and Amyloid-β Interact to Induce Cognitive and Cerebrovascular Dysfunction.

ASN Neuro 2017 Jul-Aug;9(4):1759091417719201

1 Department of Anatomy and Cell Biology, University of Illinois at Chicago, IL, USA.

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http://dx.doi.org/10.1177/1759091417719201DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521356PMC
December 2017

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.

Authors:
Rebecca Sims Sven J van der Lee Adam C Naj Céline Bellenguez Nandini Badarinarayan Johanna Jakobsdottir Brian W Kunkle Anne Boland Rachel Raybould Joshua C Bis Eden R Martin Benjamin Grenier-Boley Stefanie Heilmann-Heimbach Vincent Chouraki Amanda B Kuzma Kristel Sleegers Maria Vronskaya Agustin Ruiz Robert R Graham Robert Olaso Per Hoffmann Megan L Grove Badri N Vardarajan Mikko Hiltunen Markus M Nöthen Charles C White Kara L Hamilton-Nelson Jacques Epelbaum Wolfgang Maier Seung-Hoan Choi Gary W Beecham Cécile Dulary Stefan Herms Albert V Smith Cory C Funk Céline Derbois Andreas J Forstner Shahzad Ahmad Hongdong Li Delphine Bacq Denise Harold Claudia L Satizabal Otto Valladares Alessio Squassina Rhodri Thomas Jennifer A Brody Liming Qu Pascual Sánchez-Juan Taniesha Morgan Frank J Wolters Yi Zhao Florentino Sanchez Garcia Nicola Denning Myriam Fornage John Malamon Maria Candida Deniz Naranjo Elisa Majounie Thomas H Mosley Beth Dombroski David Wallon Michelle K Lupton Josée Dupuis Patrice Whitehead Laura Fratiglioni Christopher Medway Xueqiu Jian Shubhabrata Mukherjee Lina Keller Kristelle Brown Honghuang Lin Laura B Cantwell Francesco Panza Bernadette McGuinness Sonia Moreno-Grau Jeremy D Burgess Vincenzo Solfrizzi Petra Proitsi Hieab H Adams Mariet Allen Davide Seripa Pau Pastor L Adrienne Cupples Nathan D Price Didier Hannequin Ana Frank-García Daniel Levy Paramita Chakrabarty Paolo Caffarra Ina Giegling Alexa S Beiser Vilmantas Giedraitis Harald Hampel Melissa E Garcia Xue Wang Lars Lannfelt Patrizia Mecocci Gudny Eiriksdottir Paul K Crane Florence Pasquier Virginia Boccardi Isabel Henández Robert C Barber Martin Scherer Lluis Tarraga Perrie M Adams Markus Leber Yuning Chen Marilyn S Albert Steffi Riedel-Heller Valur Emilsson Duane Beekly Anne Braae Reinhold Schmidt Deborah Blacker Carlo Masullo Helena Schmidt Rachelle S Doody Gianfranco Spalletta W T Longstreth Thomas J Fairchild Paola Bossù Oscar L Lopez Matthew P Frosch Eleonora Sacchinelli Bernardino Ghetti Qiong Yang Ryan M Huebinger Frank Jessen Shuo Li M Ilyas Kamboh John Morris Oscar Sotolongo-Grau Mindy J Katz Chris Corcoran Melanie Dunstan Amy Braddel Charlene Thomas Alun Meggy Rachel Marshall Amy Gerrish Jade Chapman Miquel Aguilar Sarah Taylor Matt Hill Mònica Díez Fairén Angela Hodges Bruno Vellas Hilkka Soininen Iwona Kloszewska Makrina Daniilidou James Uphill Yogen Patel Joseph T Hughes Jenny Lord James Turton Annette M Hartmann Roberta Cecchetti Chiara Fenoglio Maria Serpente Marina Arcaro Carlo Caltagirone Maria Donata Orfei Antonio Ciaramella Sabrina Pichler Manuel Mayhaus Wei Gu Alberto Lleó Juan Fortea Rafael Blesa Imelda S Barber Keeley Brookes Chiara Cupidi Raffaele Giovanni Maletta David Carrell Sandro Sorbi Susanne Moebus Maria Urbano Alberto Pilotto Johannes Kornhuber Paolo Bosco Stephen Todd David Craig Janet Johnston Michael Gill Brian Lawlor Aoibhinn Lynch Nick C Fox John Hardy Roger L Albin Liana G Apostolova Steven E Arnold Sanjay Asthana Craig S Atwood Clinton T Baldwin Lisa L Barnes Sandra Barral Thomas G Beach James T Becker Eileen H Bigio Thomas D Bird Bradley F Boeve James D Bowen Adam Boxer James R Burke Jeffrey M Burns Joseph D Buxbaum Nigel J Cairns Chuanhai Cao Chris S Carlson Cynthia M Carlsson Regina M Carney Minerva M Carrasquillo Steven L Carroll Carolina Ceballos Diaz Helena C Chui David G Clark David H Cribbs Elizabeth A Crocco Charles DeCarli Malcolm Dick Ranjan Duara Denis A Evans Kelley M Faber Kenneth B Fallon David W Fardo Martin R Farlow Steven Ferris Tatiana M Foroud Douglas R Galasko Marla Gearing Daniel H Geschwind John R Gilbert Neill R Graff-Radford Robert C Green John H Growdon Ronald L Hamilton Lindy E Harrell Lawrence S Honig Matthew J Huentelman Christine M Hulette Bradley T Hyman Gail P Jarvik Erin Abner Lee-Way Jin Gyungah Jun Anna Karydas Jeffrey A Kaye Ronald Kim Neil W Kowall Joel H Kramer Frank M LaFerla James J Lah James B Leverenz Allan I Levey Ge Li Andrew P Lieberman Kathryn L Lunetta 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Winslow Antonio Daniele Chuang-Kuo Wu Oliver Peters Benedetta Nacmias Matthias Riemenschneider Reinhard Heun Carol Brayne David C Rubinsztein Jose Bras Rita Guerreiro Ammar Al-Chalabi Christopher E Shaw John Collinge David Mann Magda Tsolaki Jordi Clarimón Rebecca Sussams Simon Lovestone Michael C O'Donovan Michael J Owen Timothy W Behrens Simon Mead Alison M Goate Andre G Uitterlinden Clive Holmes Carlos Cruchaga Martin Ingelsson David A Bennett John Powell Todd E Golde Caroline Graff Philip L De Jager Kevin Morgan Nilufer Ertekin-Taner Onofre Combarros Bruce M Psaty Peter Passmore Steven G Younkin Claudine Berr Vilmundur Gudnason Dan Rujescu Dennis W Dickson Jean-François Dartigues Anita L DeStefano Sara Ortega-Cubero Hakon Hakonarson Dominique Campion Merce Boada John Keoni Kauwe Lindsay A Farrer Christine Van Broeckhoven M Arfan Ikram Lesley Jones Jonathan L Haines Christophe Tzourio Lenore J Launer Valentina Escott-Price Richard Mayeux Jean-François Deleuze Najaf Amin Peter A Holmans Margaret A Pericak-Vance Philippe Amouyel Cornelia M van Duijn Alfredo Ramirez Li-San Wang Jean-Charles Lambert Sudha Seshadri Julie Williams Gerard D Schellenberg

Nat Genet 2017 09 17;49(9):1373-1384. Epub 2017 Jul 17.

Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA.

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September 2017

Detecting novel micro RNAs in rheumatoid arthritis with gene-based association testing.

Clin Exp Rheumatol 2017 Jul-Aug;35(4):586-592. Epub 2017 Jan 27.

Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, USA.

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August 2017

Impact of home visit capacity on genetic association studies of late-onset Alzheimer's disease.

Alzheimers Dement 2017 Aug 21;13(8):933-939. Epub 2017 Feb 21.

Department of Medicine, University of Washington, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jalz.2017.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5554082PMC
August 2017

Gene-based association study of genes linked to hippocampal sclerosis of aging neuropathology: GRN, TMEM106B, ABCC9, and KCNMB2.

Neurobiol Aging 2017 05 9;53:193.e17-193.e25. Epub 2017 Jan 9.

Department of Biostatistics, University of Kentucky, Lexington, KY, USA; Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5385271PMC
May 2017

CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN.

Exp Gerontol 2017 04 9;90:83-89. Epub 2017 Feb 9.

Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA; Department of Pathology, College of Medicine, University of Kentucky, Lexington, KY, USA.

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http://dx.doi.org/10.1016/j.exger.2017.01.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389672PMC
April 2017

Functional human promoter polymorphism and variation of mental processing speed in older adults.

Aging (Albany NY) 2017 04;9(4):1293-1306

Department of Molecular Neuroscience, the Krasnow Institute for Advanced Study, George Mason University, Fairfax, VA 22030, USA.

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http://dx.doi.org/10.18632/aging.101228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5425128PMC
April 2017

Governance practices and performance in US academic medical centers.

Am J Med Qual 2015 Nov-Dec;30(6):520-5. Epub 2014 Aug 19.

University HealthSystem Consortium, Chicago, IL.

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http://dx.doi.org/10.1177/1062860614547260DOI Listing
January 2017

On combining family- and population-based sequencing data.

BMC Proc 2016 18;10(Suppl 7):175-179. Epub 2016 Oct 18.

Department of Biostatistics, University of Kentucky College of Public Health, 111 Washington Ave, Lexington, KY 40536-0003 USA.

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http://dx.doi.org/10.1186/s12919-016-0026-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133531PMC
October 2016

Comparing performance of non-tree-based and tree-based association mapping methods.

BMC Proc 2016 18;10(Suppl 7):405-410. Epub 2016 Oct 18.

Department of Biostatistics, University of Kentucky College of Public Health, Lexington, KY 40536-0003 USA.

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http://dx.doi.org/10.1186/s12919-016-0063-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133494PMC
October 2016

Causal effect estimation in sequencing studies: a Bayesian method to account for confounder adjustment uncertainty.

BMC Proc 2016 18;10(Suppl 7):411-415. Epub 2016 Oct 18.

Department of Biostatistics, College of Public Health, University of Kentucky, 725 Rose St, Lexington, KY 40536 USA.

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http://dx.doi.org/10.1186/s12919-016-0064-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133506PMC
October 2016

Automated quality control for genome wide association studies.

F1000Res 2016 29;5:1889. Epub 2016 Jul 29.

Department of Biostatistics,, University of Kentucky, Lexington, KY, 40536, USA.

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http://dx.doi.org/10.12688/f1000research.9271.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007749PMC
September 2016

Diabetes is associated with cerebrovascular but not Alzheimer's disease neuropathology.

Alzheimers Dement 2016 08 23;12(8):882-9. Epub 2016 Jan 23.

Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA; Rush University Medical Center, Department of Neurological Sciences, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.jalz.2015.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958598PMC
August 2016

Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.

Authors:
Genevera I Allen Nicola Amoroso Catalina Anghel Venkat Balagurusamy Christopher J Bare Derek Beaton Roberto Bellotti David A Bennett Kevin L Boehme Paul C Boutros Laura Caberlotto Cristian Caloian Frederick Campbell Elias Chaibub Neto Yu-Chuan Chang Beibei Chen Chien-Yu Chen Ting-Ying Chien Tim Clark Sudeshna Das Christos Davatzikos Jieyao Deng Donna Dillenberger Richard J B Dobson Qilin Dong Jimit Doshi Denise Duma Rosangela Errico Guray Erus Evan Everett David W Fardo Stephen H Friend Holger Fröhlich Jessica Gan Peter St George-Hyslop Satrajit S Ghosh Enrico Glaab Robert C Green Yuanfang Guan Ming-Yi Hong Chao Huang Jinseub Hwang Joseph Ibrahim Paolo Inglese Anandhi Iyappan Qijia Jiang Yuriko Katsumata John S K Kauwe Arno Klein Dehan Kong Roland Krause Emilie Lalonde Mario Lauria Eunjee Lee Xihui Lin Zhandong Liu Julie Livingstone Benjamin A Logsdon Simon Lovestone Tsung-Wei Ma Ashutosh Malhotra Lara M Mangravite Taylor J Maxwell Emily Merrill John Nagorski Aishwarya Namasivayam Manjari Narayan Mufassra Naz Stephen J Newhouse Thea C Norman Ramil N Nurtdinov Yen-Jen Oyang Yudi Pawitan Shengwen Peng Mette A Peters Stephen R Piccolo Paurush Praveen Corrado Priami Veronica Y Sabelnykova Philipp Senger Xia Shen Andrew Simmons Aristeidis Sotiras Gustavo Stolovitzky Sabina Tangaro Andrea Tateo Yi-An Tung Nicholas J Tustison Erdem Varol George Vradenburg Michael W Weiner Guanghua Xiao Lei Xie Yang Xie Jia Xu Hojin Yang Xiaowei Zhan Yunyun Zhou Fan Zhu Hongtu Zhu Shanfeng Zhu

Alzheimers Dement 2016 06 11;12(6):645-53. Epub 2016 Apr 11.

School of Computer Science, Fudan University, Shanghai, Shanghai, China; Shanghai Key Lab of Intelligent Information Processing, Fudan University, Shanghai, Shanghai, China; Centre for Computational Systems Biology, Fudan University, Shanghai, China.

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http://dx.doi.org/10.1016/j.jalz.2016.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474755PMC
June 2016

"New Old Pathologies": AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS).

J Neuropathol Exp Neurol 2016 06 21;75(6):482-98. Epub 2016 May 21.

From the Department of Pathology, Division of Neuropathology (PTN, JHN), Department of Neurology (GAJ, FAS, CDS), Department of Statistics (DWF, RJK), Department of Anatomy and Neurobiology (PTN, JHN, LJVE, ETI), Department of Epidemiology (ELA), and Sanders-Brown Center on Aging (PTN, ELA, OMA-J, GAJ, FAS, CDS, DWF, WXW, RJK, LJVE, ETI), University of Kentucky, Lexington, Kentucky; Department of Pathology & Laboratory Medicine and Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, Pennsylvannia (JQT); Department of Epidemiology, University of Washington, Seattle, Washington (WAK); and Department of Pathology, Houston Methodist Hospital, Houston, Texas (MDC).

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https://academic.oup.com/jnen/article-lookup/doi/10.1093/jne
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http://dx.doi.org/10.1093/jnen/nlw033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366658PMC
June 2016

An ecological systems examination of elder abuse: a week in the life of adult protective services.

J Elder Abuse Negl 2014 ;26(5):440-57

a Institute for Biomedical Ethics , University of Basel , Basel , Switzerland.

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http://dx.doi.org/10.1080/08946566.2013.800463DOI Listing
November 2015

ABCC9/SUR2 in the brain: Implications for hippocampal sclerosis of aging and a potential therapeutic target.

Ageing Res Rev 2015 Nov 28;24(Pt B):111-25. Epub 2015 Jul 28.

University of Kentucky, Sanders-Brown Center on Aging, Lexington, KY 40536, USA; Department of Biostatistics, Lexington, KY, 40536, USA.

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http://dx.doi.org/10.1016/j.arr.2015.07.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661124PMC
November 2015

A Summary Score for the Framingham Heart Study Neuropsychological Battery.

J Aging Health 2015 Oct 24;27(7):1199-222. Epub 2015 Mar 24.

University of Kentucky, Lexington, USA.

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http://journals.sagepub.com/doi/10.1177/0898264315577590
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http://dx.doi.org/10.1177/0898264315577590DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4603385PMC
October 2015

Genetics ignite focus on microglial inflammation in Alzheimer's disease.

Mol Neurodegener 2015 Oct 5;10:52. Epub 2015 Oct 5.

Department of Physiology and Sanders-Brown Center on Aging, University of Kentucky, 800 S. Limestone St, Lexington, KY, 40536, USA.

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http://www.molecularneurodegeneration.com/content/pdf/s13024
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http://www.molecularneurodegeneration.com/content/10/1/52
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http://dx.doi.org/10.1186/s13024-015-0048-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4595327PMC
October 2015

Openness to Change: Experiential and Demographic Components of Change in Local Health Department Leaders.

Front Public Health 2015 1;3:209. Epub 2015 Sep 1.

Department of Biostatistics, University of Kentucky , Lexington, KY , USA.

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http://dx.doi.org/10.3389/fpubh.2015.00209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554942PMC
September 2015

Genetics of PICALM expression and Alzheimer's disease.

PLoS One 2014 11;9(3):e91242. Epub 2014 Mar 11.

Sanders-Brown Center on Aging, Department of Physiology, University of Kentucky, Lexington, Kentucky, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3949918PMC
May 2015

Board oversight of patient care quality in large nonprofit health systems.

Am J Med Qual 2014 Jan-Feb;29(1):39-43. Epub 2013 May 7.

1University of Kentucky, Lexington, KY.

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http://dx.doi.org/10.1177/1062860613485407DOI Listing
April 2015

Self-reported head injury and risk of late-life impairment and AD pathology in an AD center cohort.

Dement Geriatr Cogn Disord 2014 31;37(5-6):294-306. Epub 2013 Dec 31.

University of Kentucky Alzheimer's Disease Center, Sanders-Brown Center on Aging, University of Kentucky, Lexington, Ky., USA.

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http://dx.doi.org/10.1159/000355478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4057973PMC
February 2015

Reassessment of risk genotypes (GRN, TMEM106B, and ABCC9 variants) associated with hippocampal sclerosis of aging pathology.

J Neuropathol Exp Neurol 2015 Jan;74(1):75-84

From the Departments of Pathology (PTN) and Biostatistics (DWF), Sanders-Brown Center on Aging (PTN, W-XW, BRW, DWF), and Division of Biomedical Informatics, College of Public Health (SRE), University of Kentucky, Lexington, Kentucky; Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (ABP, OV, L-SW); National Alzheimer's Coordinating Center (SEM) and Department of Epidemiology (WAK), University of Washington, Seattle, Washington; and Department of Biostatistics and Epidemiology, Perelman School of Medicine (ACN).

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http://dx.doi.org/10.1097/NEN.0000000000000151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4270894PMC
January 2015

A 2-step penalized regression method for family-based next-generation sequencing association studies.

BMC Proc 2014 17;8(Suppl 1):S25. Epub 2014 Jun 17.

Department of Biostatistics, University of Kentucky College of Public Health, 111 Washington Ave, Lexington, KY 40536-0003, USA.

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http://dx.doi.org/10.1186/1753-6561-8-S1-S25DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143756PMC
December 2014

Modeling of multivariate longitudinal phenotypes in family genetic studies with Bayesian multiplicity adjustment.

BMC Proc 2014 17;8(Suppl 1):S69. Epub 2014 Jun 17.

Department of Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA ; Department of Pediatrics, University of Cincinnati College of Medicine, 3235 Eden Avenue,Cincinnati, OH 45267, USA.

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http://dx.doi.org/10.1186/1753-6561-8-S1-S69DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143665PMC
December 2014

Using Mendelian inheritance errors as quality control criteria in whole genome sequencing data set.

BMC Proc 2014 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S21. Epub 2014 Jun 17.

Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA ; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1186/1753-6561-8-S1-S21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4144465PMC
December 2014

On family-based genome-wide association studies with large pedigrees: observations and recommendations.

BMC Proc 2014 17;8(Suppl 1 Genetic Analysis Workshop 18Vanessa Olmo):S26. Epub 2014 Jun 17.

Department of Pediatrics, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA ; Department of Pediatrics, University of Cincinnati College of Medicine, 2600 Clifton Ave, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1186/1753-6561-8-S1-S26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143718PMC
December 2014

Self-reported memory complaints: implications from a longitudinal cohort with autopsies.

Neurology 2014 Oct 24;83(15):1359-65. Epub 2014 Sep 24.

From the Sanders-Brown Center on Aging (R.J.K., E.L.A., G.E.C., G.A.J., P.T.N., C.D.S., L.J.V.E., L.W., F.A.S.), Alzheimer's Disease Center (R.J.K., E.L.A., G.E.C., D.W.F., G.A.J., P.T.N., C.D.S., L.J.V.E., F.A.S.), Departments of Biostatistics (R.J.K., D.W.F.), Statistics (R.J.K., L.W.), Epidemiology (E.L.A.), and Pathology (P.T.N.), Department of Anatomy and Neurobiology, College of Medicine (L.J.V.E.), and Department of Neurology, College of Medicine (G.A.J., C.D.S., F.A.S.), University of Kentucky, Lexington; and Baptist Neurology Center (G.E.C.), Lexington, KY.

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http://dx.doi.org/10.1212/WNL.0000000000000856DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4189103PMC
October 2014

Longitudinal trajectories of cholesterol from midlife through late life according to apolipoprotein E allele status.

Int J Environ Res Public Health 2014 Oct 16;11(10):10663-93. Epub 2014 Oct 16.

Sanders-Brown Center on Aging, University of Kentucky, 101 Sanders-Brown Building, 800 S. Limestone Street, Lexington, KY 40536, USA.

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http://dx.doi.org/10.3390/ijerph111010663DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4211000PMC
October 2014

Complex pedigrees in the sequencing era: to track transmissions or decorrelate?

Genet Epidemiol 2014 Sep;38 Suppl 1:S29-36

Medical Genetics Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America; David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America.

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http://dx.doi.org/10.1002/gepi.21822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272198PMC
September 2014

The relationship between midlife and late life alcohol consumption, APOE e4 and the decline in learning and memory among older adults.

Alcohol Alcohol 2014 Jan-Feb;49(1):17-22. Epub 2013 Sep 18.

Corresponding author: Graduate Center for Gerontology, University of Kentucky College of Public Health, 740 South Limestone, J524 KY Clinic, Lexington, KY, 40536-0284, USA.

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http://dx.doi.org/10.1093/alcalc/agt144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865814PMC
August 2014

An intronic PICALM polymorphism, rs588076, is associated with allelic expression of a PICALM isoform.

Mol Neurodegener 2014 Aug 29;9:32. Epub 2014 Aug 29.

Departments of Physiology, Sanders-Brown Center on Aging, University of Kentucky, 800 S, Limestone St,, Lexington, KY 40536, USA.

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http://dx.doi.org/10.1186/1750-1326-9-32DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4150683PMC
August 2014

Assessment of Appalachian region pediatric hearing healthcare disparities and delays.

Laryngoscope 2014 Jul 10;124(7):1713-7. Epub 2014 Feb 10.

Department of Otolaryngology-Head and Neck Surgery, University of Kentucky, Lexington, Kentucky, U.S.A.

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http://dx.doi.org/10.1002/lary.24588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4069222PMC
July 2014

Delays in diagnosis of congenital hearing loss in rural children.

J Pediatr 2014 Feb 30;164(2):393-7. Epub 2013 Oct 30.

Department of Behavioral Science, University of Kentucky, Lexington, KY.

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http://dx.doi.org/10.1016/j.jpeds.2013.09.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946850PMC
February 2014

ABCA7 expression is associated with Alzheimer's disease polymorphism and disease status.

Neurosci Lett 2013 Nov 18;556:58-62. Epub 2013 Oct 18.

Department of Physiology, Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, United States.

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http://dx.doi.org/10.1016/j.neulet.2013.09.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3863933PMC
November 2013

Combining genetic association study designs: a GWAS case study.

Front Genet 2013 27;4:186. Epub 2013 Sep 27.

Department of Biostatistics, University of Kentucky Lexington, KY, USA.

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http://dx.doi.org/10.3389/fgene.2013.00186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784826PMC
October 2013

CD33 Alzheimer's risk-altering polymorphism, CD33 expression, and exon 2 splicing.

J Neurosci 2013 Aug;33(33):13320-5

Department of Physiology, Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky 40536, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.1224-13.2013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742922PMC
August 2013

APOE-ε2 and APOE-ε4 correlate with increased amyloid accumulation in cerebral vasculature.

J Neuropathol Exp Neurol 2013 Jul;72(7):708-15

Sanders Brown Center on Aging, University of Kentucky, Lexington, Kentucky, USA.

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http://dx.doi.org/10.1097/NEN.0b013e31829a25b9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715146PMC
July 2013

Statistical Approaches to Combine Genetic Association Data.

J Biom Biostat 2013 Jun;4(3):1000166

Department of Biostatistics, University of Colorado, 13001 E. 17 St, Aurora CO 80045, USA.

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http://dx.doi.org/10.4172/2155-6180.1000166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3760734PMC
June 2013

Genetics and non-syndromic facial growth.

J Pediatr Genet 2013 Mar;2(1):9-20

Department of Biostatistics, University of Kentucky College of Public Health, Lexington, KY, USA.

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http://dx.doi.org/10.3233/PGE-13041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020952PMC
March 2013

Genetics of clusterin isoform expression and Alzheimer's disease risk.

PLoS One 2012 10;7(4):e33923. Epub 2012 Apr 10.

Department of Physiology and Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3323613PMC
October 2012

Gene-environment interaction testing in family-based association studies with phenotypically ascertained samples: a causal inference approach.

Biostatistics 2012 Jul 13;13(3):468-81. Epub 2011 Nov 13.

Department of Biostatistics, Division of Biomedical Informatics, Center for Clinical and Translational Science, University of Kentucky, Lexington, KY 40536, USA.

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http://dx.doi.org/10.1093/biostatistics/kxr035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3372944PMC
July 2012

Families or Unrelated: The Evolving Debate in Genetic Association Studies.

J Biom Biostat 2012 Jun;3(4):e108

Department of Human Genetics, Emory University, 615 Michael St, Atlanta GA 30322.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112473PMC
June 2012

Exploration and comparison of methods for combining population- and family-based genetic association using the Genetic Analysis Workshop 17 mini-exome.

BMC Proc 2011 Nov 29;5 Suppl 9:S28. Epub 2011 Nov 29.

Department of Biostatistics, University of Kentucky College of Public Health, 121 Washington Avenue, Lexington, KY 40536, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287863PMC
November 2011

Race-ethnicity as an effect modifier of the association between HbAlc and mortality in U.S. adults without diagnosed diabetes.

Eur J Endocrinol 2011 Aug 26;165(2):275-81. Epub 2011 May 26.

Department of Epidemiology, College of Public Health, University of Kentucky, Suite 213, 121 Washington Avenue, Lexington, Kentucky 40536-0003, USA.

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http://dx.doi.org/10.1530/EJE-11-0171DOI Listing
August 2011

Sclerostin and Dickkopf-1 in renal osteodystrophy.

Clin J Am Soc Nephrol 2011 Apr 16;6(4):877-82. Epub 2010 Dec 16.

Division of Nephrology, Medical University Vienna, Vienna, Austria.

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http://dx.doi.org/10.2215/CJN.06550810DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3069382PMC
April 2011

Recovering unused information in genome-wide association studies: the benefit of analyzing SNPs out of Hardy-Weinberg equilibrium.

Eur J Hum Genet 2009 Dec 3;17(12):1676-82. Epub 2009 Jun 3.

Department of Biostatistics, University of Kentucky College of Public Health, Lexington, KY 40536, USA.

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http://dx.doi.org/10.1038/ejhg.2009.85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796342PMC
December 2009

On quality control measures in genome-wide association studies: a test to assess the genotyping quality of individual probands in family-based association studies and an application to the HapMap data.

PLoS Genet 2009 Jul 24;5(7):e1000572. Epub 2009 Jul 24.

Department of Biostatistics, University of Kentucky College of Public Health, Lexington, Kentucky, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2706974PMC
July 2009

Predictors of an accurate preoperative sestamibi scan for single-gland parathyroid adenomas.

Arch Surg 2007 Apr;142(4):381-6

Department of Surgical Oncology, Massachusetts General Hospital, and Harvard Medical School, Boston, MA 02114, USA.

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April 2007