David Venzon

David Venzon

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David Venzon

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Optimized Timing of Post-Transplantation Cyclophosphamide in MHC-Haploidentical Murine Hematopoietic Cell Transplantation: Optimized timing of PTCy in haploidentical HCT.

Biol Blood Marrow Transplant 2019 Oct 2. Epub 2019 Oct 2.

Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbmt.2019.09.030DOI Listing
October 2019

Differential Effect of Mucosal NKp44 Innate Lymphoid Cells and Δγ Cells on Simian Immunodeficiency Virus Infection Outcome in Rhesus Macaques.

J Immunol 2019 Sep 25. Epub 2019 Sep 25.

Vaccine Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; and

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http://dx.doi.org/10.4049/jimmunol.1900572DOI Listing
September 2019

Severe Hepatotoxicity of Mithramycin Therapy Caused by Altered Expression of Hepatocellular Bile Transporters.

Mol Pharmacol 2019 Aug 7;96(2):158-167. Epub 2019 Jun 7.

Clinical Pharmacology Program (T.M.S., C.J.P., W.D.F.), Molecular Pharmacology Section (P.A.H., R.J.H., E.M.M., R.H.B., J.D.S., A.M.L., W.D.F.), Biostatistics and Data Management Section (M.Z., J.A.H., D.V.), Pediatric Oncology Branch (P.G., J.G., B.C.W.), Thoracic Surgery Branch, Center for Cancer Research, National Cancer Institute (D.S.S.), and Translational Hepatology Section (T.H.), Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland; and BioIVT, ADME-Tox Division, Durham, North Carolina (J.P.J., K.R.B.)

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http://dx.doi.org/10.1124/mol.118.114827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608607PMC
August 2019

Differential Expression of CD43, CD81, and CD200 in Classic Versus Variant Hairy Cell Leukemia.

Cytometry B Clin Cytom 2019 Jul 11;96(4):275-282. Epub 2019 May 11.

Laboratory of Pathology, CCR, NCI, NIH, Bethesda, Maryland.

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http://dx.doi.org/10.1002/cyto.b.21785DOI Listing
July 2019

The effect of anti-CTLA4 treatment on peripheral and intra-tumoral T cells in patients with hepatocellular carcinoma.

Cancer Immunol Immunother 2019 Apr 28;68(4):599-608. Epub 2019 Jan 28.

Gastrointestinal Malignancies Section, Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health (NIH), Building 10, Room 3B43, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s00262-019-02299-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6662600PMC
April 2019

Post-transplantation cyclophosphamide prevents graft-versus-host disease by inducing alloreactive T cell dysfunction and suppression.

J Clin Invest 2019 03 26;129(6):2357-2373. Epub 2019 Mar 26.

Experimental Transplantation and Immunology Branch, Center for Cancer Research, National Cancer Institute (NCI).

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http://dx.doi.org/10.1172/JCI124218DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546453PMC
March 2019

Neutrophil Vaccination Dynamics and Their Capacity To Mediate B Cell Help in Rhesus Macaques.

J Immunol 2018 10 14;201(8):2287-2302. Epub 2018 Sep 14.

Immune Biology of Retroviral Infection Section, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;

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http://dx.doi.org/10.4049/jimmunol.1800677DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6179953PMC
October 2018

Influence of gut microbiome on mucosal immune activation and SHIV viral transmission in naive macaques.

Mucosal Immunol 2018 07 1;11(4):1219-1229. Epub 2018 Jun 1.

Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1038/s41385-018-0029-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030500PMC
July 2018

Beyond Oncolytics: E1B55K-Deleted Adenovirus as a Vaccine Delivery Vector.

PLoS One 2016 8;11(7):e0158505. Epub 2016 Jul 8.

Section on Immune Biology of Retroviral Infection, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0158505PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938603PMC
August 2017

Carfilzomib and lenalidomide response related to VEGF and VEGFR2 germline polymorphisms.

Cancer Chemother Pharmacol 2017 Jul 9;80(1):217-221. Epub 2017 May 9.

Clinical Pharmacology Program, Office of the Clinical Director, National Cancer Institute, 9000 Rockville Pike, Building 10, Rm 5A01, Bethesda, MD, 20892, USA.

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http://dx.doi.org/10.1007/s00280-017-3323-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6387687PMC
July 2017

Blockade of only TGF-β 1 and 2 is sufficient to enhance the efficacy of vaccine and PD-1 checkpoint blockade immunotherapy.

Oncoimmunology 2017 31;6(5):e1308616. Epub 2017 Mar 31.

Vaccine Branch and Data Management Section, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1080/2162402X.2017.1308616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5467996PMC
March 2017

Mesothelin-targeted immunotoxin RG7787 has synergistic anti-tumor activity when combined with taxanes.

Oncotarget 2017 Feb;8(6):9189-9199

Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.18632/oncotarget.13984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354724PMC
February 2017

Mucosal and Systemic γδ+ T Cells Associated with Control of Simian Immunodeficiency Virus Infection.

J Immunol 2016 12 4;197(12):4686-4695. Epub 2016 Nov 4.

Immune Biology of Retroviral Infection Section, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; and

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http://dx.doi.org/10.4049/jimmunol.1600579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136305PMC
December 2016

Expression of mesothelin in thymic carcinoma and its potential therapeutic significance.

Lung Cancer 2016 11 28;101:104-110. Epub 2016 Sep 28.

Thoracic and Gastrointestinal Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.09.015DOI Listing
November 2016

Relationship between Vaccine-Induced Antibody Capture of Infectious Virus and Infection Outcomes following Repeated Low-Dose Rectal Challenges with Simian Immunodeficiency Virus SIVmac251.

J Virol 2016 10 12;90(19):8487-95. Epub 2016 Sep 12.

Division of Infectious Diseases, Departments of Medicine and Molecular Biology & Biochemistry, University of California, Irvine, California, USA

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http://dx.doi.org/10.1128/JVI.00812-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021405PMC
October 2016

B Cell Responses Associated with Vaccine-Induced Delayed SIVmac251 Acquisition in Female Rhesus Macaques.

J Immunol 2016 09 17;197(6):2316-24. Epub 2016 Aug 17.

Section on Immune Biology of Retroviral Infection, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892; and

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http://dx.doi.org/10.4049/jimmunol.1600544DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010965PMC
September 2016

Erratum to: Association of a CYP17 Polymorphism With Overall Survival in Caucasian Patients With Androgen-independent Prostate Cancer.

Urology 2016 09 14;95:225. Epub 2016 Jul 14.

Clinical Pharmacology Program, National Cancer Institute, Bethesda, MD. Electronic address:

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http://dx.doi.org/10.1016/j.urology.2016.05.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5676461PMC
September 2016

Early SIV Dissemination After Intrarectal SIVmac251 Challenge Was Associated With Proliferating Virus-Susceptible Cells in the Colorectum.

J Acquir Immune Defic Syndr 2016 Apr;71(4):353-8

*Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD; †Advanced BioScience Laboratories, Inc., Rockville, MD; and ‡Biostatistics and Data Management Section, National Cancer Institute, National Institutes of Health, Bethesda, MD.

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http://pdfs.journals.lww.com/jaids/2016/04010/Early_SIV_Diss
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http://dx.doi.org/10.1097/QAI.0000000000000890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4767727PMC
April 2016

Resection of primary tumor site is associated with prolonged survival in metastatic nonfunctioning pancreatic neuroendocrine tumors.

Surgery 2016 Jan 6;159(1):311-8. Epub 2015 Oct 6.

Endocrine Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD. Electronic address:

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http://dx.doi.org/10.1016/j.surg.2015.05.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688058PMC
January 2016

Loss of marginal zone B-cells in SHIVSF162P4 challenged rhesus macaques despite control of viremia to low or undetectable levels in chronic infection.

Virology 2015 Oct 4;484:323-33. Epub 2015 Jul 4.

Section on Immune Biology of Retroviral Infection, Vaccine Branch, National Cancer Institute, Bethesda, MD 20892, United States. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2015.06.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567457PMC
October 2015

Class II human leucocyte antigen DRB1*11 in hairy cell leukaemia patients with and without haemolytic uraemic syndrome.

Br J Haematol 2014 Sep 13;166(5):729-38. Epub 2014 Jun 13.

Laboratory of Molecular Biology, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1111/bjh.12956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4134696PMC
September 2014

Phenotypes and distribution of mucosal memory B-cell populations in the SIV/SHIV rhesus macaque model.

Clin Immunol 2014 Aug 9;153(2):264-76. Epub 2014 May 9.

Section on Immune Biology of Retroviral Infection, Vaccine Branch, National Cancer Institute, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2014.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4086409PMC
August 2014

In vivo evaluation of safety and toxicity of a Lactobacillus jensenii producing modified cyanovirin-N in a rhesus macaque vaginal challenge model.

PLoS One 2013 12;8(11):e78817. Epub 2013 Nov 12.

Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0078817PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827103PMC
July 2014

Cancer-associated CD43 glycoforms as target of immunotherapy.

Mol Cancer Ther 2014 Mar 19;13(3):752-62. Epub 2013 Dec 19.

Corresponding Authors: Franca Maria Tuccillo, Laboratory of Molecular Biology and Viral Oncogenesis, Istituto Nazionale per lo Studio e la Cura dei Tumori "Fondazione G. Pascale", IRCCS, via Mariano Semmola, 80131, Naples, Italy.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-0651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954431PMC
March 2014

Rhesus macaque rectal and duodenal tissues exhibit B-cell sub-populations distinct from peripheral blood that continuously secrete antigen-specific IgA in short-term explant cultures.

Vaccine 2014 Feb 25;32(7):872-80. Epub 2013 Dec 25.

Section on Immune Biology of Retroviral Infection, Vaccine Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2013.12.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916903PMC
February 2014

Assessment of tumor growth in pancreatic neuroendocrine tumors in von Hippel Lindau syndrome.

J Am Coll Surg 2014 Feb 12;218(2):163-9. Epub 2013 Nov 12.

Endocrine Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD. Electronic address:

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http://dx.doi.org/10.1016/j.jamcollsurg.2013.10.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3896892PMC
February 2014

Measurements of the pons as a biomarker of progression for pediatric DIPG.

J Neurooncol 2014 Jan 10;116(1):127-33. Epub 2013 Oct 10.

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Building 10/Room 1-5750, 9000 Rockville Pike, Bethesda, MD, 20892, USA,

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http://dx.doi.org/10.1007/s11060-013-1266-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301003PMC
January 2014

Delicate balance among three types of T cells in concurrent regulation of tumor immunity.

Cancer Res 2013 Mar 14;73(5):1514-23. Epub 2013 Jan 14.

Vaccine Branch and Biostatistics and Data Management Section, Center for Cancer Research, National Cancer Institute/NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-2567DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3622595PMC
March 2013

Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A.

Proc Natl Acad Sci U S A 2012 Dec 3;109(51):E3597-603. Epub 2012 Dec 3.

Laboratory of Molecular Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.1218138109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529021PMC
December 2012

Single- and multivoxel proton spectroscopy in pediatric patients with diffuse intrinsic pontine glioma.

Int J Radiat Oncol Biol Phys 2012 Nov 23;84(3):774-9. Epub 2012 Mar 23.

Pediatric Oncology Branch, National Cancer Institute, Building 10/Room 1-5750, 9000 Rockville Pike, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ijrobp.2012.01.032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3386374PMC
November 2012

Flow cytometry increases the sensitivity of detection of leukemia and lymphoma cells in bronchoalveolar lavage specimens.

Cytometry B Clin Cytom 2012 Sep 26;82(5):305-12. Epub 2012 Jul 26.

Hematopathology Section, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/cyto.b.21033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598592PMC
September 2012

Sorafenib is an inhibitor of UGT1A1 but is metabolized by UGT1A9: implications of genetic variants on pharmacokinetics and hyperbilirubinemia.

Clin Cancer Res 2012 Apr 3;18(7):2099-107. Epub 2012 Feb 3.

Clinical Pharmacology Program, Pharmacology and Experimental Therapeutics Section, Molecular Pharmacology Section, Biostatistics and Data Management Branch, Medical Oncology Branch, and HIV/AIDS Malignancy Branch, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-2484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6432766PMC
April 2012

Combined normal donor and CLL: Single tube ZAP-70 analysis.

Cytometry B Clin Cytom 2012 Mar 26;82(2):67-77. Epub 2011 Oct 26.

Center for Biologics Evaluation and Research, FDA, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1002/cyto.b.20622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407416PMC
March 2012

Expression of OATP family members in hormone-related cancers: potential markers of progression.

PLoS One 2011 19;6(5):e20372. Epub 2011 May 19.

Molecular Pharmacology Section, National Cancer Institute, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020372PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098289PMC
October 2011

Methodological comparison of two anti-ZAP-70 antibodies.

Cytometry B Clin Cytom 2011 Sep 6;80(5):300-8. Epub 2011 Apr 6.

Center for Biologics Evaluation and Research, Food & Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1002/cyto.b.20591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461319PMC
September 2011

Improved ZAP-70 assay using two clones, multiple methods of analysis and clinical correlation.

Cytometry B Clin Cytom 2011 Sep 6;80(5):309-17. Epub 2011 Apr 6.

Division of Cellular, Tissue and Gene Therapies, Center for Biologics Evaluation and Research, Food & Drug Administration, 8800 Rockville Pike, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1002/cyto.b.20593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3407415PMC
September 2011

Estrogen receptor α and aromatase polymorphisms affect risk, prognosis, and therapeutic outcome in men with castration-resistant prostate cancer treated with docetaxel-based therapy.

J Clin Endocrinol Metab 2011 Feb 24;96(2):E368-72. Epub 2010 Nov 24.

Clinical Pharmacology Program, Medical Oncology Branch, National Cancer Institute, 9000 Rockville Pike, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1210/jc.2010-2070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3048329PMC
February 2011

TLR3-specific double-stranded RNA oligonucleotide adjuvants induce dendritic cell cross-presentation, CTL responses, and antiviral protection.

J Immunol 2011 Feb 17;186(4):2422-9. Epub 2011 Jan 17.

Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.4049/jimmunol.1002845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078629PMC
February 2011