David V Serreze

David V Serreze

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David V Serreze

David V Serreze

Publications by authors named "David V Serreze"

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Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation.

Cell Rep 2019 Dec;29(10):3073-3086.e5

Department of Microbiology and Immunology, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA; Department of Pediatrics, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA; Max McGee National Research Center for Juvenile Diabetes, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.11.010DOI Listing
December 2019

Combined congenic mapping and nuclease-based gene targeting for studying allele-specific effects of Tnfrsf9 within the Idd9.3 autoimmune diabetes locus.

Sci Rep 2019 Mar 13;9(1):4316. Epub 2019 Mar 13.

Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, 53226, USA.

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http://dx.doi.org/10.1038/s41598-019-40898-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416332PMC
March 2019

HLA-B*39:06 Efficiently Mediates Type 1 Diabetes in a Mouse Model Incorporating Reduced Thymic Insulin Expression.

J Immunol 2018 05 9;200(10):3353-3363. Epub 2018 Apr 9.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461;

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http://dx.doi.org/10.4049/jimmunol.1701652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940557PMC
May 2018

Bridging Mice to Men: Using HLA Transgenic Mice to Enhance the Future Prediction and Prevention of Autoimmune Type 1 Diabetes in Humans.

Methods Mol Biol 2016 ;1438:137-51

Department of Microbiology & Immunology, Albert Einstein College of Medicine, Bronx, NY, 10461, USA.

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http://dx.doi.org/10.1007/978-1-4939-3661-8_9DOI Listing
December 2017

Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice.

Immunogenetics 2017 03 28;69(3):193-198. Epub 2016 Oct 28.

Department of Pediatrics, Max McGee National Research Center for Juvenile Diabetes, Medical College of Wisconsin, Milwaukee, WI, 53226, USA.

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http://dx.doi.org/10.1007/s00251-016-0957-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5335865PMC
March 2017

B7x in the periphery abrogates pancreas-specific damage mediated by self-reactive CD8 T cells.

J Immunol 2012 Oct 12;189(8):4165-74. Epub 2012 Sep 12.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.4049/jimmunol.1201241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466330PMC
October 2012

Targeting of a T cell agonist peptide to lysosomes by DNA vaccination induces tolerance in the nonobese diabetic mouse.

J Immunol 2011 Apr 23;186(7):4078-87. Epub 2011 Feb 23.

Department of Physiology and Immunology, Faculty of Biology, University of Barcelona, 08028 Barcelona, Spain.

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.0902395
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http://dx.doi.org/10.4049/jimmunol.0902395DOI Listing
April 2011

Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease.

Semin Immunopathol 2011 Jan 28;33(1):67-87. Epub 2010 Apr 28.

The Jackson Laboratory, Bar Harbor, ME, USA.

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http://link.springer.com/10.1007/s00281-010-0204-1
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http://dx.doi.org/10.1007/s00281-010-0204-1DOI Listing
January 2011

Enhanced responsiveness to T-cell help causes loss of B-lymphocyte tolerance to a β-cell neo-self-antigen in type 1 diabetes prone NOD mice.

Eur J Immunol 2010 Dec 11;40(12):3413-25. Epub 2010 Nov 11.

Immunology Program, Garvan Institute of Medical Research, Darlinghurst, NSW, Australia.

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http://dx.doi.org/10.1002/eji.201040817DOI Listing
December 2010

Peripherin-reactive antibodies in mouse, rabbit, and human blood.

J Proteome Res 2010 Mar;9(3):1203-8

Chronic Disease Program, Ottawa Hospital Research Institute, Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.

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http://pubs.acs.org/doi/abs/10.1021/pr900492y
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http://dx.doi.org/10.1021/pr900492yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3023150PMC
March 2010

Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells.

J Immunol Methods 2008 Jun 8;335(1-2):106-15. Epub 2008 Apr 8.

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1016/j.jim.2008.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430474PMC
June 2008

In vivo cytotoxicity of insulin-specific CD8+ T-cells in HLA-A*0201 transgenic NOD mice.

Diabetes 2007 Oct 9;56(10):2551-60. Epub 2007 Jul 9.

Albert Einstein College of Medicine, Department of Microbiology and Immunology, 1300 Morris Park Ave., Bronx, NY 10461, USA.

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http://dx.doi.org/10.2337/db07-0332DOI Listing
October 2007

Subcongenic analysis of genetic basis for impaired development of invariant NKT cells in NOD mice.

Immunogenetics 2007 Sep 10;59(9):705-12. Epub 2007 Jul 10.

The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.

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http://link.springer.com/content/pdf/10.1007/s00251-007-0236
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http://link.springer.com/10.1007/s00251-007-0236-4
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http://dx.doi.org/10.1007/s00251-007-0236-4DOI Listing
September 2007

"Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes.

Ann N Y Acad Sci 2007 Apr 21;1103:103-11. Epub 2007 Mar 21.

The Jackson Laboratory, Bar Harbor, ME 04609, USA.

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http://dx.doi.org/10.1196/annals.1394.019DOI Listing
April 2007

Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity.

Nat Genet 2007 Mar 4;39(3):329-37. Epub 2007 Feb 4.

Julia McFarlane Diabetes Research Centre (JMDRC) and Department of Microbiology and Infectious Diseases, Institute of Inflammation, Infection and Immunity, Faculty of Medicine, The University of Calgary, Calgary, Alberta T2N 4N1, Canada.

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http://dx.doi.org/10.1038/ng1958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2886969PMC
March 2007

Invasion of the killer B's in type 1 diabetes.

Front Biosci 2007 Jan 1;12:2183-93. Epub 2007 Jan 1.

Garvan Institute of Medical Research, 384 Victoria Street, Darlinghurst NSW 2010, Australia.

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http://dx.doi.org/10.2741/2221DOI Listing
January 2007

Of mice and men: use of animal models to identify possible interventions for the prevention of autoimmune type 1 diabetes in humans.

Trends Immunol 2005 Nov 2;26(11):603-7. Epub 2005 Sep 2.

The Jackson Laboratory, 600 Main St, Bar Harbor, ME 04609, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S147149060500232
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http://dx.doi.org/10.1016/j.it.2005.08.012DOI Listing
November 2005

The good turned ugly: immunopathogenic basis for diabetogenic CD8+ T cells in NOD mice.

Immunol Rev 2005 Apr;204:250-63

Department of Microbiology, Division of Endocrinology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1111/j.0105-2896.2005.00244.xDOI Listing
April 2005

Autoimmune diabetes and resistance to xenograft transplantation tolerance in NOD mice.

Diabetes 2005 Jan;54(1):107-15

University of Massachusetts Medical School, Diabetes Division, Department of Medicine, 373 Plantation St., Biotech 2, Suite 218, Worcester, MA 01605, USA.

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http://dx.doi.org/10.2337/diabetes.54.1.107DOI Listing
January 2005

Was there type 1 diabetes in the Olduvai Gorge?

Adv Exp Med Biol 2004 ;552:322-5

The Jackson Laboratory, Bar Harbor, Maine, USA.

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January 2005

Individual nonobese diabetic mice exhibit unique patterns of CD8+ T cell reactivity to three islet antigens, including the newly identified widely expressed dystrophia myotonica kinase.

J Immunol 2004 Dec;173(11):6727-34

Department of Microbiology and Immunology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA.

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http://dx.doi.org/10.4049/jimmunol.173.11.6727DOI Listing
December 2004

Requirement for both H-2Db and H-2Kd for the induction of diabetes by the promiscuous CD8+ T cell clonotype AI4.

J Immunol 2004 Aug;173(4):2530-41

Departments of Microbiology and Immunology, and Medicine (Division of Endocrinology), Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.4049/jimmunol.173.4.2530DOI Listing
August 2004

Islet cell autoimmunity and transplantation tolerance: two distinct mechanisms?

Ann N Y Acad Sci 2003 Nov;1005:148-56

Program in Immunology and Virology, University of Massachusetts Medical School, Worcester, Massachusetts 01605, USA.

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http://dx.doi.org/10.1196/annals.1288.016DOI Listing
November 2003

Tracking autoimmune T cells in diabetes.

J Clin Invest 2003 Sep;112(6):826-8

The Jackson Laboratory, 600 Main Street, Bar Harbor, Maine 04609, USA.

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http://www.jci.org/articles/view/19842
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http://dx.doi.org/10.1172/JCI19842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC193678PMC
September 2003

Genetic separation of the transplantation tolerance and autoimmune phenotypes in NOD mice.

Rev Endocr Metab Disord 2003 Sep;4(3):255-61

Program in Immunology and Virology, at The University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA.

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http://dx.doi.org/10.1023/a:1025152312496DOI Listing
September 2003

The role of B lymphocytes as key antigen-presenting cells in the development of T cell-mediated autoimmune type 1 diabetes.

Curr Dir Autoimmun 2003 ;6:212-27

Jackson Laboratory, Bar Harbor, Me., USA.

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http://dx.doi.org/10.1159/000066863DOI Listing
May 2003

NOD congenic mice genetically protected from autoimmune diabetes remain resistant to transplantation tolerance induction.

Diabetes 2003 Feb;52(2):321-6

Program in Immunology and Virology, University of Massachusetts Medical School, Worcester 01605, USA.

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http://dx.doi.org/10.2337/diabetes.52.2.321DOI Listing
February 2003

During the early prediabetic period in NOD mice, the pathogenic CD8(+) T-cell population comprises multiple antigenic specificities.

Clin Immunol 2002 Dec;105(3):332-41

Department of Microbiology and Infectious Diseases, Faculty of Medicine, University of Calgary, Calgary, Alberta, T2N 4N1, Canada.

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http://dx.doi.org/10.1006/clim.2002.5298DOI Listing
December 2002