David Taft

David Taft

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David Taft

David Taft

Publications by authors named "David Taft"

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Effect of Gender on the Pharmacokinetics of ON 123300, A Dual Inhibitor of ARK5 and CDK4/6 for the Treatment of Cancer, in Rats.

Eur J Drug Metab Pharmacokinet 2019 Aug;44(4):531-538

Onconova Therapeutics, Inc., Newtown, PA, USA.

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http://dx.doi.org/10.1007/s13318-019-00542-2DOI Listing
August 2019

Learn to segment single cells with deep distance estimator and deep cell detector.

Comput Biol Med 2019 May 8;108:133-141. Epub 2019 Apr 8.

Department of Computational and System Biology, University of Pittsburgh, Pittsburgh, PA, 15260, USA; UPMC-Hillman Cancer Center, University of Pittsburgh, Pittsburgh, 15232, PA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.compbiomed.2019.04.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781873PMC
May 2019

Spatial clustering and common regulatory elements correlate with coordinated gene expression.

PLoS Comput Biol 2019 03 1;15(3):e1006786. Epub 2019 Mar 1.

Department of Computational and Systems Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1006786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6415868PMC
March 2019

Using PBPK Modeling to Predict Drug Exposure and Support Dosage Adjustments in Patients With Renal Impairment: An Example With Lamivudine.

Curr Drug Discov Technol 2019 Feb 14. Epub 2019 Feb 14.

Samuel J. and Joan B. Williamson Institute for Pharmacometrics, Division of Pharmaceutical Sciences, Arnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York. United States.

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http://dx.doi.org/10.2174/1570163816666190214164916DOI Listing
February 2019

Real-World Experience With Higher-Than-Recommended Doses of Lamivudine in Patients With Varying Degrees of Renal Impairment.

Open Forum Infect Dis 2018 Oct 10;5(10):ofy225. Epub 2018 Sep 10.

Division of Pharmacy Practice, The Arnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York.

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https://academic.oup.com/ofid/article/doi/10.1093/ofid/ofy22
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http://dx.doi.org/10.1093/ofid/ofy225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6171568PMC
October 2018

Application of physiologically based pharmacokinetic modeling to predict drug disposition in pregnant populations.

Biopharm Drug Dispos 2017 Oct 13;38(7):426-438. Epub 2017 Jul 13.

Samuel J. and Joan B. Williamson Institute for Pharmacometrics, Arnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, New York, USA.

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http://dx.doi.org/10.1002/bdd.2081DOI Listing
October 2017

Evaluating the Potential for Delivery of Irinotecan via the Buccal Route: Physicochemical Characterization and In Vitro Permeation Assessment Across Porcine Buccal Mucosa.

AAPS PharmSciTech 2017 Apr 30;18(3):867-874. Epub 2016 Jun 30.

Division of Pharmaceutical Sciences, Long Island University, Brooklyn, New York, 11201, USA.

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http://dx.doi.org/10.1208/s12249-016-0578-zDOI Listing
April 2017

Stability of sotalol hydrochloride in extemporaneously prepared oral suspension formulations.

Int J Pharm Compd 2005 Sep-Oct;9(5):402-6

Division of Pharmaceutical Sciences, Long Island University, Brooklyn, New York.

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July 2015

Phase I clinical trial of oral rigosertib in patients with myelodysplastic syndromes.

Br J Haematol 2013 Aug 21;162(4):517-24. Epub 2013 Jun 21.

Department of Hematological Malignancies, H Lee Moffitt Cancer Center and Research Institute, Tampa, FL 33612, USA.

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http://dx.doi.org/10.1111/bjh.12436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685467PMC
August 2013

Determination of intestinal permeability of rigosertib (ON 01910.Na, Estybon): correlation with systemic exposure.

J Pharm Pharmacol 2013 Jul 25;65(7):960-9. Epub 2013 Mar 25.

Division of Pharmaceutical Sciences, Arnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, Brooklyn, NY 11201, USA.

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http://dx.doi.org/10.1111/jphp.12057DOI Listing
July 2013

Disposition of ON 01210.Na (Ex-RAD(R)), a novel radioprotectant, in the isolated perfused rat liver: probing metabolic inhibition to increase systemic exposure.

J Pharm Sci 2013 Feb 4;102(2):732-40. Epub 2012 Dec 4.

Division of Pharmaceutical Sciences, Long Island University, Brooklyn, New York 11201, USA.

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http://dx.doi.org/10.1002/jps.23391DOI Listing
February 2013

Radioprotective effects of ON 01210.Na upon oral administration.

J Radiat Res 2012 11;53(3):368-76. Epub 2012 May 11.

Department of Biochemistry and Molecular & Cellular Biology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057-1468, USA.

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http://jrr.oxfordjournals.org/content/53/3/368.full.pdf
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http://dx.doi.org/10.1269/jrr.11191DOI Listing
January 2013

Aristolochic acid I metabolism in the isolated perfused rat kidney.

Chem Res Toxicol 2012 Jan 14;25(1):130-9. Epub 2011 Dec 14.

Department of Biological Sciences, Florida International University , Miami, Florida 33199, United States.

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http://dx.doi.org/10.1021/tx200333gDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276251PMC
January 2012

Renal excretion of apricitabine in rats: ex vivo and in vivo studies.

Eur J Drug Metab Pharmacokinet 2011 Sep 6;36(3):141-50. Epub 2011 Apr 6.

College of Pharmacy, Long Island University, 75 DeKalb Avenue, Brooklyn, NY 11201, USA.

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http://dx.doi.org/10.1007/s13318-011-0038-9DOI Listing
September 2011

Effects of formulation and route of administration on the systemic availability of Ex-RAD®, a new radioprotectant, in preclinical species.

Biopharm Drug Dispos 2011 Mar 14;32(2):99-111. Epub 2011 Jan 14.

Division of Pharmaceutical Sciences, Long Island University, Brooklyn, NY 11201, USA.

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http://dx.doi.org/10.1002/bdd.741DOI Listing
March 2011

Renal excretion of clofarabine: assessment of dose-linearity and role of renal transport systems on drug excretion.

Eur J Pharm Sci 2010 Jun 25;40(3):209-16. Epub 2010 Mar 25.

Division of Pharmaceutical Sciences, Arnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, 75 Dekalb Avenue, Brooklyn, NY 11201, USA.

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http://dx.doi.org/10.1016/j.ejps.2010.03.014DOI Listing
June 2010

Comparative renal excretion of VX-702, a novel p38 MAPK inhibitor, and methotrexate in the perfused rat kidney model.

Drug Dev Ind Pharm 2010 Mar;36(3):315-22

Division of Pharmaceutical Sciences, Long Island University, Brooklyn, NY 11201, USA.

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http://dx.doi.org/10.3109/03639040903154200DOI Listing
March 2010

Preclinical pharmacokinetics and in vitro activity of ON 01910.Na, a novel anti-cancer agent.

Cancer Chemother Pharmacol 2009 Dec 24;65(1):177-86. Epub 2009 May 24.

Division of Pharmaceutical Sciences, Long Island University, Brooklyn, NY 11201, USA.

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http://dx.doi.org/10.1007/s00280-009-1022-9DOI Listing
December 2009

Renal excretion of emtricitabine I: effects of organic anion, organic cation, and nucleoside transport inhibitors on emtricitabine excretion.

J Pharm Sci 2008 Dec;97(12):5401-10

Division of Pharmaceutical Sciences, Arnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, 75 DeKalb Ave., Brooklyn, New York 11201, USA.

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http://dx.doi.org/10.1002/jps.21370DOI Listing
December 2008

Renal excretion of emtricitabine II. effect of trimethoprim on emtricitabine excretion: In vitro and in vivo studies.

J Pharm Sci 2008 Dec;97(12):5411-20

Division of Pharmaceutical Sciences, Arnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, 75 DeKalb Ave., Brooklyn, New York 11201, USA.

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http://dx.doi.org/10.1002/jps.21369DOI Listing
December 2008

Effects of trimethoprim on the clearance of apricitabine, a deoxycytidine analog reverse transcriptase inhibitor, and Lamivudine in the isolated perfused rat kidney.

J Pharmacol Exp Ther 2006 Nov 22;319(2):941-7. Epub 2006 Aug 22.

Division of Pharmaceutical Sciences, Long Island University, 75 DeKalb Avenue, Brooklyn, NY 11201, USA.

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http://dx.doi.org/10.1124/jpet.106.108522DOI Listing
November 2006

Effects of morning versus evening administration of atorvastatin in patients with hyperlipidemia.

Am J Health Syst Pharm 2005 Dec;62(23):2491-4

Arnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University (LIU), 75 DeKalb Avenue, Brooklyn, NY 11201-5497, USA.

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http://dx.doi.org/10.2146/ajhp050072DOI Listing
December 2005

Measuring drug concentrations using pulsatile microdialysis: theory and method development in vitro.

Int J Pharm 2005 Apr;293(1-2):171-82

Division of Pharmaceutical Sciences, Arnold and Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, 75 DeKalb Avenue, Brooklyn, NY 11201, USA.

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http://dx.doi.org/10.1016/j.ijpharm.2004.12.012DOI Listing
April 2005

The isolated perfused rat kidney model: a useful tool for drug discovery and development.

Authors:
David R Taft

Curr Drug Discov Technol 2004 Jan;1(1):97-111

Division of Pharmaceutics and Industrial Pharmacy, Long Island University, 75 DeKalb Avenue, Brooklyn, NY 11201, USA.

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http://dx.doi.org/10.2174/1570163043484824DOI Listing
January 2004

Characterization of pentamidine excretion in the isolated perfused rat kidney.

J Antimicrob Chemother 2003 Sep 29;52(3):397-404. Epub 2003 Jul 29.

Division of Pharmaceutics and Industrial Pharmacy, Arnold & Marie Schwartz College of Pharmacy and Health Sciences, Long Island University, 75 DeKalb Avenue, Brooklyn, NY 11201, USA.

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http://dx.doi.org/10.1093/jac/dkg341DOI Listing
September 2003

In vitro evaluation of the release of albuterol sulfate from polymer gels: effect of fatty acids on drug transport across biological membranes.

Drug Dev Ind Pharm 2002 Nov;28(10):1221-9

Division of Pharmaceutics and Industrial Pharmacy, Arnold & Marie Schwartz College of Pharmacy & Health Sciences, Long Island University, Brooklyn, NY 11201, USA.

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http://dx.doi.org/10.1081/ddc-120015355DOI Listing
November 2002

A novel HPLC assay for pentamidine: comparative effects of creatinine and inulin on GFR estimation and pentamidine renal excretion in the isolated perfused rat kidney.

J Pharm Pharm Sci 2002 May-Aug;5(2):135-45

Division of Pharmaceutics and Industrial Pharmacy, Long Island University, Brooklyn, New York, USA.

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September 2002

Simulation of the pharmacokinetic profile of methazolamide in blood: effect of erythrocyte carbonic anhydrase binding on drug disposition.

Pharm Res 2002 Apr;19(4):551-5

Division of Pharmaceutics and Industrial Pharmacy, Long Island University, Brooklyn, New York 11201, USA.

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http://dx.doi.org/10.1023/a:1015120418178DOI Listing
April 2002