Publications by authors named "David T Weaver"

36Publications

Combinatorial Inhibition of Focal Adhesion Kinase and BCL-2 Enhances Antileukemia Activity of Venetoclax in Acute Myeloid Leukemia.

Mol Cancer Ther 2020 08 13;19(8):1636-1648. Epub 2020 May 13.

Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-19-0841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7416436PMC
August 2020

PYK2/FAK inhibitors reverse hypoxia-induced drug resistance in multiple myeloma.

Haematologica 2019 07 17;104(7):e310-e313. Epub 2019 Jan 17.

Department of Radiation Oncology, Cancer Biology Division, Washington University in Saint Louis School of Medicine, Saint Louis, MO, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2018.194688DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601110PMC
July 2019

Inactivation of deubiquitinase CYLD enhances therapeutic antibody production in Chinese hamster ovary cells.

Appl Microbiol Biotechnol 2018 Jul 15;102(14):6081-6093. Epub 2018 May 15.

Institute of Physical Science and Information Technology, Anhui University, Hefei, Anhui, 230601, People's Republic of China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00253-018-9070-xDOI Listing
July 2018

Characterization of an Lrp/AsnC family regulator SCO3361, controlling actinorhodin production and morphological development in Streptomyces coelicolor.

Appl Microbiol Biotechnol 2017 Jul 11;101(14):5773-5783. Epub 2017 Jun 11.

Institute of Health Sciences, School of Chemistry and Chemical Engineering, School of Life Sciences, Anhui University, Hefei, 230601, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00253-017-8339-9DOI Listing
July 2017

Focal Adhesion Kinase as a Potential Target in AML and MDS.

Mol Cancer Ther 2017 06 7;16(6):1133-1144. Epub 2017 Mar 7.

Section of Molecular Hematology and Therapy, Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-16-0719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457713PMC
June 2017

Engineering of an Lrp family regulator SACE_Lrp improves erythromycin production in Saccharopolyspora erythraea.

Metab Eng 2017 01 26;39:29-37. Epub 2016 Oct 26.

Institute of Health Sciences, School of Chemistry and Chemical Engineering, School of Life Sciences, Anhui University, Hefei 230601, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymben.2016.10.012DOI Listing
January 2017

Inactivation of SACE_3446, a TetR family transcriptional regulator, stimulates erythromycin production in .

Synth Syst Biotechnol 2016 Mar 16;1(1):39-46. Epub 2016 Feb 16.

Institute of Health Sciences, School of Life Sciences, Anhui University, Hefei 230601, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.synbio.2016.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640589PMC
March 2016

In vivo investigation to the macrolide-glycosylating enzyme pair DesVII/DesVIII in Saccharopolyspora erythraea.

Appl Microbiol Biotechnol 2016 Mar 10;100(5):2257-66. Epub 2015 Nov 10.

Institute of Health Sciences, School of Life Sciences, Anhui University, Hefei, 230601, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00253-015-7036-9DOI Listing
March 2016

c-Abl regulates proteasome abundance by controlling the ubiquitin-proteasomal degradation of PSMA7 subunit.

Cell Rep 2015 Feb 22;10(4):484-96. Epub 2015 Jan 22.

Beijing Institute of Biotechnology, Beijing 100850, China. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2014.12.044DOI Listing
February 2015

DNA repair biomarkers XPF and phospho-MAPKAP kinase 2 correlate with clinical outcome in advanced head and neck cancer.

PLoS One 2014 14;9(7):e102112. Epub 2014 Jul 14.

Department of Medicine, Section of Hematology/Oncology, The University of Chicago, Chicago, Illinois, United States of America; The University of Chicago Comprehensive Cancer Center, Chicago, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102112PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096922PMC
November 2015

SACE_3986, a TetR family transcriptional regulator, negatively controls erythromycin biosynthesis in Saccharopolyspora erythraea.

J Ind Microbiol Biotechnol 2014 Jul 3;41(7):1159-67. Epub 2014 May 3.

Institute of Health Sciences, School of Life Sciences, Anhui University, Hefei, 230601, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10295-014-1449-9DOI Listing
July 2014

DNA repair biomarkers predict response to neoadjuvant chemoradiotherapy in esophageal cancer.

Int J Radiat Oncol Biol Phys 2012 May 12;83(1):164-71. Epub 2011 Oct 12.

Department of Radiation Oncology, Dana-Farber/Brigham and Women's Cancer Center, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ijrobp.2011.05.033DOI Listing
May 2012

The ups and downs of DNA repair biomarkers for PARP inhibitor therapies.

Am J Cancer Res 2011;1(3):301-327. Epub 2010 Jan 3.

On-Q-ity, Inc. 610 Lincoln St. Waltham, Massachusetts, 02451, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3180060PMC
January 2010

XPF expression correlates with clinical outcome in squamous cell carcinoma of the head and neck.

Clin Cancer Res 2011 Aug 7;17(16):5513-22. Epub 2011 Jul 7.

Departments of Otolaryngology and Head and Neck Surgery, University of Pittsburgh School of Medicine and University of Pittsburgh Cancer Institute, PA 15213, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-11-0086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156890PMC
August 2011

DNA repair protein biomarkers associated with time to recurrence in triple-negative breast cancer.

Clin Cancer Res 2010 Dec;16(23):5796-804

Dana Farber/Brigham and Women's Cancer Center Department of Radiation Oncology, Harvard Medical School, Boston, Massachusetts, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-10-0292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4220607PMC
December 2010

Crystal structures of the FXIa catalytic domain in complex with ecotin mutants reveal substrate-like interactions.

J Biol Chem 2005 Feb 15;280(6):4704-12. Epub 2004 Nov 15.

Daiichi Asubio Medical Research Laboratories LLC, Cambridge, Massachusetts 02139, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M411309200DOI Listing
February 2005

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair.

Mol Cell Biol 2004 Jan;24(2):708-18

Department of Radiation Oncology, Massachusetts General Hospital/Harvard Medical School, 149 13th Street, Charlestown, MA 02129, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC343805PMC
http://dx.doi.org/10.1128/mcb.24.2.708-718.2004DOI Listing
January 2004

Interaction of FANCD2 and NBS1 in the DNA damage response.

Nat Cell Biol 2002 Dec;4(12):913-20

Department of Pediatric Oncology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncb879DOI Listing
December 2002