David T Ting

David T Ting

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David T Ting

David T Ting

Publications by authors named "David T Ting"

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Glioblastoma-Associated Microglia Reprogramming Is Mediated by Functional Transfer of Extracellular miR-21.

Cell Rep 2019 Sep;28(12):3105-3119.e7

Departments of Neurology and Radiology, Massachusetts General Hospital, and NeuroDiscovery Center, Harvard Medical School, Boston, MA 02129, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.08.036DOI Listing
September 2019

Quasimesenchymal phenotype predicts systemic metastasis in pancreatic ductal adenocarcinoma.

Mod Pathol 2019 Jun 25;32(6):844-854. Epub 2019 Jan 25.

Department of Pathology, Massachusetts General Hospital, Boston, MA and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41379-018-0196-2DOI Listing
June 2019

Reply.

Gastroenterology 2019 05 27;156(6):1933-1934. Epub 2019 Mar 27.

MGH Cancer Center, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1053/j.gastro.2019.03.042DOI Listing
May 2019

The histological diagnosis of IgG4-related disease on small biopsies: challenges and pitfalls.

Histopathology 2019 Apr 10;74(5):688-698. Epub 2019 Mar 10.

Department of Pathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.

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http://doi.wiley.com/10.1111/his.13787
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http://dx.doi.org/10.1111/his.13787DOI Listing
April 2019

No Cell Left Unturned: Intraductal Papillary Mucinous Neoplasm Heterogeneity.

Clin Cancer Res 2019 Apr 14;25(7):2027-2029. Epub 2019 Jan 14.

Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-3877DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445728PMC
April 2019

A Code of Mono-phosphorylation Modulates the Function of RB.

Mol Cell 2019 03 30;73(5):985-1000.e6. Epub 2019 Jan 30.

Massachusetts General Hospital Cancer Center and Harvard Medical School, Building 149 13th Street, Charlestown, MA 02129, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6424368PMC
March 2019

A tumor-specific endogenous repetitive element is induced by herpesviruses.

Nat Commun 2019 01 9;10(1):90. Epub 2019 Jan 9.

Department of Medicine, Hematology and Medical Oncology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

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http://dx.doi.org/10.1038/s41467-018-07944-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6327058PMC
January 2019

In Reply.

Oncologist 2018 10 10;23(10):e120. Epub 2018 Oct 10.

Cancer Center, Department of Medicine, Harvard Medical School, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1634/theoncologist.2018-0374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263126PMC
October 2018

Global Cancer Transcriptome Quantifies Repeat Element Polarization between Immunotherapy Responsive and T Cell Suppressive Classes.

Cell Rep 2018 Apr;23(2):512-521

Tisch Cancer Institute, Departments of Medicine, Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Department of Oncological Sciences and Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Precision Immunology Institute at the Icahn School of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.03.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6016853PMC
April 2018

Single-Cell Analysis of Circulating Tumor Cells as a Window into Tumor Heterogeneity.

Cold Spring Harb Symp Quant Biol 2016 7;81:269-274. Epub 2017 Apr 7.

Massachusetts General Hospital Cancer Center, Boston, Massachusetts 02114.

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http://dx.doi.org/10.1101/sqb.2016.81.031120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501288PMC
February 2018

Introducing cancer convergence.

Cancer Converg 2017 1;1(1). Epub 2017 Nov 1.

6Oregon State University, Corvallis, OR USA.

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http://dx.doi.org/10.1186/s41236-017-0003-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5876691PMC
November 2017

X-inactive specific transcript RNA in-situ hybridization as a tool for resolving specimen contamination events.

Histopathology 2017 10 19;71(4):662-665. Epub 2017 Jul 19.

Department of Pathology, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1111/his.13267DOI Listing
October 2017

STK38L kinase ablation promotes loss of cell viability in a subset of KRAS-dependent pancreatic cancer cell lines.

Oncotarget 2017 Oct 11;8(45):78556-78572. Epub 2017 Sep 11.

Department of Pharmacology and Experimental Therapeutics, Center for Cancer Research, Boston University Graduate School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.18632/oncotarget.20833DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667982PMC
October 2017

The Human Long Interspersed Element-1 Retrotransposon: An Emerging Biomarker of Neoplasia.

Clin Chem 2017 04 10;63(4):816-822. Epub 2017 Feb 10.

McKusick-Nathans Institute of Genetic Medicine (IGM) and

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http://dx.doi.org/10.1373/clinchem.2016.257444DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6177209PMC
April 2017

Branched Chain RNA In Situ Hybridization for Androgen Receptor Splice Variant AR-V7 as a Prognostic Biomarker for Metastatic Castration-Sensitive Prostate Cancer.

Clin Cancer Res 2017 Jan 20;23(2):363-369. Epub 2016 Jul 20.

Massachusetts General Hospital Cancer Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/1078-0432.CCR-16-0237DOI Listing
January 2017

A tunable delivery platform to provide local chemotherapy for pancreatic ductal adenocarcinoma.

Biomaterials 2016 07 31;93:71-82. Epub 2016 Mar 31.

Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, MA, USA; Cardiovascular Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.biomaterials.2016.03.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4849535PMC
July 2016

P53 and the defenses against genome instability caused by transposons and repetitive elements.

Bioessays 2016 06 13;38(6):508-13. Epub 2016 May 13.

Department of Medicine, Hematology, and Medical Oncology, and Pathology, Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031199PMC
http://dx.doi.org/10.1002/bies.201600031DOI Listing
June 2016

Performance of a Branch Chain RNA In Situ Hybridization Assay for the Detection of High-risk Human Papillomavirus in Head and Neck Squamous Cell Carcinoma.

Am J Surg Pathol 2015 Dec;39(12):1643-52

Departments of *Pathology ‡Surgery ∥Tucker Gosnell Center for Gastrointestinal Cancers, Massachusetts General Hospital §Department of Pathology, Brigham and Women's Hospital †Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/PAS.0000000000000516DOI Listing
December 2015

Distinguishing the immunostimulatory properties of noncoding RNAs expressed in cancer cells.

Proc Natl Acad Sci U S A 2015 Dec 2;112(49):15154-9. Epub 2015 Nov 2.

Tisch Cancer Institute, Department of Medicine, Hematology, and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029; The Simons Center for Systems Biology, School of Natural Sciences, Institute for Advanced Study, Princeton, NJ 08540; Department of Pathology, Icahn School of Medicine at Mount Sinai, New York, NY 10029

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http://dx.doi.org/10.1073/pnas.1517584112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679042PMC
December 2015

Pericentromeric satellite repeat expansions through RNA-derived DNA intermediates in cancer.

Proc Natl Acad Sci U S A 2015 Dec 2;112(49):15148-53. Epub 2015 Nov 2.

Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA 02129; Howard Hughes Medical Institute, Chevy Chase, MD 20815; Department of Medicine, Massachusetts General Hospital, Boston, MA 02114;

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http://dx.doi.org/10.1073/pnas.1518008112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679016PMC
December 2015

RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance.

Science 2015 Sep;349(6254):1351-6

Massachusetts General Cancer Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA. Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

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http://dx.doi.org/10.1126/science.aab0917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4872391PMC
September 2015

Expression of Albumin mRNA in Primary Hepatic Neoplasms and Acinar Cell Carcinoma.

Am J Surg Pathol 2015 Aug;39(8):1157-8

Massachusetts General Hospital Boston, MA.

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http://dx.doi.org/10.1097/PAS.0000000000000484DOI Listing
August 2015

A microfluidic device for label-free, physical capture of circulating tumor cell clusters.

Nat Methods 2015 Jul 18;12(7):685-91. Epub 2015 May 18.

1] Center for Engineering in Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/nmeth.3404DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4490017PMC
July 2015

The WTX Tumor Suppressor Interacts with the Transcriptional Corepressor TRIM28.

J Biol Chem 2015 Jun 16;290(23):14381-90. Epub 2015 Apr 16.

Massachusetts General Hospital Cancer Center and Harvard Medical School, Charlestown, Massachusetts 02129 and From the Departments of Medicine and Howard Hughes Medical Institute, Chevy Chase, Maryland 20815

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http://dx.doi.org/10.1074/jbc.M114.631945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505506PMC
June 2015

MAPK7 Regulates EMT Features and Modulates the Generation of CTCs.

Mol Cancer Res 2015 May 12;13(5):934-43. Epub 2015 Feb 12.

Massachusetts General Hospital Cancer Center and Harvard Medical School, Charlestown, Massachusetts. Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts. Howard Hughes Medical Institute, Chevy Chase, Maryland.

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http://dx.doi.org/10.1158/1541-7786.MCR-14-0604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433453PMC
May 2015

Branched chain in situ hybridization for albumin as a marker of hepatocellular differentiation: evaluation of manual and automated in situ hybridization platforms.

Am J Surg Pathol 2015 Jan;39(1):25-34

Departments of *Surgery †Pathology ∥Medicine, Division of Oncology, Massachusetts General Hospital and Harvard Medical School Boston, MA ‡UCSF and VA Medical Center, San Francisco, CA §Department of Cellular Pathology, University Hospital Southampton NHS Foundation Trust, Southampton, UK.

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http://dx.doi.org/10.1097/PAS.0000000000000343DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698370PMC
January 2015

BRCA1 haploinsufficiency for replication stress suppression in primary cells.

Nat Commun 2014 Nov 17;5:5496. Epub 2014 Nov 17.

1] Harvard Medical School, Boston, Massachusetts 02115, USA [2] Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.

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http://www.nature.com/articles/ncomms6496
Publisher Site
http://dx.doi.org/10.1038/ncomms6496DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243249PMC
November 2014

The wide gulf between stage III and stage IV colon cancer.

Lancet Oncol 2014 Jul 11;15(8):785-6. Epub 2014 Jun 11.

Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(14)70272-4DOI Listing
July 2014

Isolation and molecular characterization of circulating melanoma cells.

Cell Rep 2014 May 18;7(3):645-53. Epub 2014 Apr 18.

Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, MA 02129, USA; Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA; Howard Hughes Medical Institute, Bethesda, MD 20815, USA. Electronic address:

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http://www.cell.com/cell-reports/pdf/S2211-1247(14)00217-4.p
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http://linkinghub.elsevier.com/retrieve/pii/S221112471400217
Publisher Site
http://dx.doi.org/10.1016/j.celrep.2014.03.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4079008PMC
May 2014

Dynamic chromatin modification sustains epithelial-mesenchymal transition following inducible expression of Snail-1.

Cell Rep 2013 Dec 19;5(6):1679-89. Epub 2013 Dec 19.

Massachusetts General Hospital Cancer Center and Harvard Medical School, Charlestown, MA 02129, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2013.11.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034764PMC
December 2013

Inducible transgene expression in mouse stem cells.

Methods Mol Med 2005 ;105:23-46

Harvard-M.I.T. Program in Health Sciences and Technology, Harvard Medical School. Boston, MA, USA.

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March 2005