Publications by authors named "David T Scadden"

251Publications

Lactate Dehydrogenase A Governs Cardiac Hypertrophic Growth in Response to Hemodynamic Stress.

Cell Rep 2020 09;32(9):108087

Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address:

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September 2020

Cell interactions in the bone marrow microenvironment affecting myeloid malignancies.

Blood Adv 2020 Aug;4(15):3795-3803

Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA; and.

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August 2020

Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance.

Cell Metab 2020 Sep 6;32(3):391-403.e6. Epub 2020 Aug 6.

Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA. Electronic address:

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September 2020

Efficacy and safety of anti-CD45-saporin as conditioning agent for RAG deficiency.

J Allergy Clin Immunol 2021 Jan 6;147(1):309-320.e6. Epub 2020 May 6.

Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Md. Electronic address:

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January 2021

A biomaterial-based vaccine eliciting durable tumour-specific responses against acute myeloid leukaemia.

Nat Biomed Eng 2020 01 14;4(1):40-51. Epub 2020 Jan 14.

John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA, USA.

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January 2020

Identification of Functionally Distinct Mx1+αSMA+ Periosteal Skeletal Stem Cells.

Cell Stem Cell 2019 12;25(6):784-796.e5

Department of Molecular Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Center for Skeletal Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA; Department of Pathology and Immunology, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. Electronic address:

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December 2019

Metcalf Lecture Award: Applying niche biology to engineer T-cell regenerative therapies.

Authors:
David T Scadden

Exp Hematol 2019 12 23;80:1-10. Epub 2019 Nov 23.

Harvard Stem Cell Institute, Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA. Electronic address:

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December 2019

Programmable microencapsulation for enhanced mesenchymal stem cell persistence and immunomodulation.

Proc Natl Acad Sci U S A 2019 07 16;116(31):15392-15397. Epub 2019 Jul 16.

John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138;

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July 2019

Stress-Induced Changes in Bone Marrow Stromal Cell Populations Revealed through Single-Cell Protein Expression Mapping.

Cell Stem Cell 2019 Oct 3;25(4):570-583.e7. Epub 2019 Jul 3.

Center for Regenerative Medicine, Massachusetts General Hospital, 185 Cambridge St., Boston, MA 02114, USA; Harvard Stem Cell Institute, 7 Divinity Ave., Cambridge, MA 02138, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address:

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October 2019

A Cellular Taxonomy of the Bone Marrow Stroma in Homeostasis and Leukemia.

Cell 2019 06 23;177(7):1915-1932.e16. Epub 2019 May 23.

Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA; Harvard Stem Cell Institute, Cambridge, MA 02138, USA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address:

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June 2019

Growing old in the age of heterogeneity: the perils of shifting clonality.

Curr Opin Hematol 2019 07;26(4):222-227

Harvard Stem Cell Institute, Cambridge.

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July 2019

Lineage Tracing Reveals a Subset of Reserve Muscle Stem Cells Capable of Clonal Expansion under Stress.

Cell Stem Cell 2019 06 18;24(6):944-957.e5. Epub 2019 Apr 18.

The Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, Department of Orthopedic Surgery, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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June 2019