Publications by authors named "David Semela"

70Publications

Primary biliary cholangitis with normal alkaline phosphatase: A neglected clinical entity challenging current guidelines.

J Autoimmun 2020 Nov 20:102578. Epub 2020 Nov 20.

Paediatric Liver, GI and Nutrition Centre, MowatLabs, King's College London Faculty of Life Sciences & Medicine at King's College Hospital, Denmark Hill, London, SE5 9RS, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaut.2020.102578DOI Listing
November 2020

Contrast-enhanced ultrasound can guide the therapeutic strategy by improving the detection of colorectal liver metastases.

J Hepatol 2020 Oct 13. Epub 2020 Oct 13.

Department of Gastroenterology and Hepatology, Kantonsspital, St. Gallen, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2020.09.036DOI Listing
October 2020

Nonalcoholic fatty liver disease burden - Switzerland 2018-2030.

Swiss Med Wkly 2019 Dec 17;149:w20152. Epub 2019 Dec 17.

Center for Disease Analysis, Lafayette, Colorado, USA 0017208903817 | 0017204423453.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4414/smw.2019.20152DOI Listing
December 2019

Efficacy of Retreatment After Failed Direct-acting Antiviral Therapy in Patients With HCV Genotype 1-3 Infections.

Clin Gastroenterol Hepatol 2019 Nov 6. Epub 2019 Nov 6.

Department of Internal Medicine 1, University Hospital Frankfurt, Frankfurt, and German Center for Infection Research (DZIF), External Partner Site, Frankfurt, Germany; Medizinische Klinik 2, St Josefs-Hospital, Wiesbaden, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cgh.2019.10.051DOI Listing
November 2019

Contrast-enhanced ultrasound (CEUS) has excellent diagnostic accuracy in differentiating focal liver lesions: results from a Swiss tertiary gastroenterological centre.

Swiss Med Wkly 2019 06 30;149:w20087. Epub 2019 Jun 30.

Department of Gastroenterology and Hepatology, Kantonsspital St. Gallen, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4414/smw.2019.20087DOI Listing
June 2019

Controlled attenuation parameter for the assessment of liver steatosis in comparison with liver histology: a single-centre real life experience.

Swiss Med Wkly 2019 Apr 26;149:w20077. Epub 2019 Apr 26.

Department of Gastroenterology/Hepatology, Cantonal Hospital St Gallen, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4414/smw.2019.20077DOI Listing
April 2019

Porto-sinusoidal vascular disease: proposal and description of a novel entity.

Lancet Gastroenterol Hepatol 2019 05;4(5):399-411

Barcelona Hepatic Hemodynamic Lab, Liver Unit, Hospital Clinic de Barcelona, University of Barcelona, Barcelona, Spain; CIBER Hepatic and Digestive Diseases, Instituto de Salud Carlos III, Madrid, Spain. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2468-1253(19)30047-0DOI Listing
May 2019

Rabbit HEV in immunosuppressed patients with hepatitis E acquired in Switzerland.

J Hepatol 2019 05 22;70(5):1023-1025. Epub 2019 Feb 22.

Division of Gastroenterology and Hepatology, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2019.01.025DOI Listing
May 2019

Microelimination of chronic hepatitis C in Switzerland: modelling the Swiss Hepatitis Strategy goals in eastern, western and northern regions.

Swiss Med Wkly 2019 01 23;149:w14694. Epub 2019 Jan 23.

Division of Gastroenterology and Hepatology, Cantonal Hospital St Gallen, Switzerland.

View Article

Download full-text PDF

Source
https://doi.emh.ch/smw.2019.14694
Publisher Site
http://dx.doi.org/10.4414/smw.2019.14694DOI Listing
January 2019

Improvement of primary biliary cholangitis (PBC) under treatment with sulfasalazine and abatacept.

BMJ Case Rep 2018 May 12;2018. Epub 2018 May 12.

Division of Rheumatology, Immunology and Rehabilitation, Kantonsspital Sankt Gallen, Sankt Gallen, Switzerland.

View Article

Download full-text PDF

Source
http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22420
Publisher Site
http://dx.doi.org/10.1136/bcr-2018-224205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5950655PMC
May 2018

Hepatitis C – Diagnostik und Therapie.

Authors:
David Semela

Ther Umsch 2017 Jul;74(3):101-108

1 Klinik für Gastroenterologie und Hepatologie, Kantonsspital St. Gallen.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1024/0040-5930/a000892DOI Listing
July 2017

Hepatocellular carcinoma recurrence after direct antiviral agent treatment: A European multicentre study.

J Hepatol 2017 10 19;67(4):876-878. Epub 2017 Jul 19.

Hepatology, Department of Clinical Research, University of Bern, Bern, Switzerland; University Clinic of Visceral Surgery and Medicine, Inselspital Bern, Bern, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2017.07.007DOI Listing
October 2017

Visualization of hepatitis E virus RNA and proteins in the human liver.

J Hepatol 2017 09 13;67(3):471-479. Epub 2017 Apr 13.

Department of Pathology and Molecular Pathology, University Zurich and University Hospital Zurich, Zurich, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2017.04.002DOI Listing
September 2017

A systematic review and meta-analysis of HCV clearance.

Liver Int 2017 10 30;37(10):1431-1445. Epub 2017 Mar 30.

Infectious Diseases Service, Department of Medicine, University Hospital and University of Lausanne, Lausanne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/liv.13401DOI Listing
October 2017

Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation.

Lab Invest 2016 09 18;96(9):972-80. Epub 2016 Jul 18.

Hepatology Laboratory, Department of Biomedicine, University and University Hospital Basel, Basel, Switzerland.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/labinvest201675
Publisher Site
http://dx.doi.org/10.1038/labinvest.2016.75DOI Listing
September 2016

Being an informal caregiver for a relative with liver cirrhosis and overt hepatic encephalopathy: a phenomenological study.

J Clin Nurs 2016 Sep 11;25(17-18):2559-68. Epub 2016 May 11.

Institute of Nursing, Zurich University of Applied Sciences (ZUAS), Winterthur, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/jocn.13298DOI Listing
September 2016

Birth cohort distribution and screening for viraemic hepatitis C virus infections in Switzerland.

Swiss Med Wkly 2015 4;145:w14221. Epub 2015 Dec 4.

Division of Gastroenterology & Hepatology, Cantonal Hospital St. Gallen, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4414/smw.2015.14221DOI Listing
September 2016

Systemic disease associated with noncirrhotic portal hypertension.

Authors:
David Semela

Clin Liver Dis (Hoboken) 2015 Oct 28;6(4):103-106. Epub 2015 Oct 28.

Department of Biomedicine, Liver Biology Lab University Basel Basel Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cld.505DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6490659PMC
October 2015

Modeling the Health and Economic Burden of Hepatitis C Virus in Switzerland.

PLoS One 2015 24;10(6):e0125214. Epub 2015 Jun 24.

Divisions of Gastroenterology and Hepatology and of Clinical Pathology, University Hospital, Genève, Switzerland.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125214PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480969PMC
March 2016

Generation of a murine hepatic angiosarcoma cell line and reproducible mouse tumor model.

Lab Invest 2015 Mar 24;95(3):351-62. Epub 2014 Nov 24.

1] Department of Biomedicine, University Basel, Basel, Switzerland [2] Division of Gastroenterology and Hepatology, Kantonsspital St. Gallen, St. Gallen, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/labinvest.2014.141DOI Listing
March 2015

"Fighting an uphill battle": experience with the HCV triple therapy: a qualitative thematic analysis.

BMC Infect Dis 2014 Sep 18;14:507. Epub 2014 Sep 18.

Cantonal Hospital St, Gallen, Division of Infectious Diseases and Hospital Epidemiology, 9007 St, Gallen, Switzerland.

View Article

Download full-text PDF

Source
http://bmcinfectdis.biomedcentral.com/articles/10.1186/1471-
Publisher Site
http://dx.doi.org/10.1186/1471-2334-14-507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174651PMC
September 2014

[Malignant hypoglycaemia].

Praxis (Bern 1994) 2014 Mar;103(7):399-403

Klinik für Gastroenterologie/Hepatologie, Kantonsspital St. Gallen.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1024/1661-8157/a001608DOI Listing
March 2014

Nodular regenerative hyperplasia in a patient with generalized essential telangiectasia: endotheliopathy as a causal factor.

Hepatology 2014 Jun 28;59(6):2419-21. Epub 2014 Apr 28.

Department of Biomedicine, University Hospital Basel, University Basel, Basel, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.26942DOI Listing
June 2014

Downregulation of the endothelial genes Notch1 and ephrinB2 in patients with nodular regenerative hyperplasia.

Liver Int 2014 Apr 21;34(4):594-603. Epub 2013 Jul 21.

Department of Biomedicine, University Hospital Basel, University Basel, Basel, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/liv.12261DOI Listing
April 2014

[Non-cirrhotic portal hypertension with nearly lethal consequences].

Praxis (Bern 1994) 2013 May;102(11):681-5

Departement Innere Medizin, Kantonsspital St. Gallen, Spital Rorschach.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1024/1661-8157/a001303DOI Listing
May 2013

Constitutive Notch2 signaling induces hepatic tumors in mice.

Hepatology 2013 Apr 14;57(4):1607-19. Epub 2013 Mar 14.

Department of Biomedicine, Hepatology Laboratory, University of Basel, Basel, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.26165DOI Listing
April 2013

TIE2-expressing monocytes: a novel cellular biomarker for hepatocellular carcinoma?

Hepatology 2013 Apr 6;57(4):1294-6. Epub 2013 Mar 6.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.26025DOI Listing
April 2013

[Hepatocellular carcinoma].

Ther Umsch 2011 Apr;68(4):213-7

Abteilung für Gastroenterologie und Hepatologie, Universitätsspital Basel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1024/0040-5930/a000153DOI Listing
April 2011

Angiogenesis in liver disease.

J Hepatol 2009 Mar 31;50(3):604-20. Epub 2008 Dec 31.

Hepatic Hemodynamic Laboratory, Liver Unit, Hospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2008.12.011DOI Listing
March 2009

Platelet-derived growth factor signaling through ephrin-b2 regulates hepatic vascular structure and function.

Gastroenterology 2008 Aug 16;135(2):671-9. Epub 2008 Apr 16.

GI Research Unit/Fitterman Center for Digestive Disease, Mayo Clinic, Rochester, Minnesota, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.gastro.2008.04.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639748PMC
August 2008

Nitric oxide promotes caspase-independent hepatic stellate cell apoptosis through the generation of reactive oxygen species.

Hepatology 2008 Jun;47(6):1983-93

Gastrointestinal Research Unit and Fiterman Center for Digestive Disease, Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hep.22285
Publisher Site
http://dx.doi.org/10.1002/hep.22285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2562502PMC
June 2008

Sinusoidal remodeling and angiogenesis: a new function for the liver-specific pericyte?

Hepatology 2007 Mar;45(3):817-25

Department of Internal Medicine, Inje University Ilsanpaik Hospital, Gyeonggi-do, South Korea.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/hep.21564
Publisher Site
http://dx.doi.org/10.1002/hep.21564DOI Listing
March 2007

Vascular remodeling and antitumoral effects of mTOR inhibition in a rat model of hepatocellular carcinoma.

J Hepatol 2007 May 17;46(5):840-8. Epub 2007 Jan 17.

Institute of Clinical Pharmacology, University of Berne, Murtenstrasse 35, CH-3010 Berne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2006.11.021DOI Listing
May 2007

Nitric oxide promotes endothelial cell survival signaling through S-nitrosylation and activation of dynamin-2.

J Cell Sci 2007 Feb;120(Pt 3):492-501

GI Research Unit, Department of Physiology and Tumor Biology Program, Mayo Clinic, Rochester, MN 55903, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.03361DOI Listing
February 2007

GRK2 makes trouble: a no-NO in portal hypertension.

Gastroenterology 2006 Mar;130(3):1001-3; discussion 1003

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S001650850600091
Publisher Site
http://dx.doi.org/10.1053/j.gastro.2005.11.053DOI Listing
March 2006

Angiogenesis and hepatocellular carcinoma.

J Hepatol 2004 Nov;41(5):864-80

Institute of Clinical Pharmacology, University of Bern, 35 Murtenstrasse, Bern CH-3010, Switzerland.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S016882780400394
Publisher Site
http://dx.doi.org/10.1016/j.jhep.2004.09.006DOI Listing
November 2004

Effect of vascular endothelial growth factor on functional recovery after hepatectomy in lean and obese mice.

J Hepatol 2004 Feb;40(2):305-12

Department of Visceral and Transplantation Surgery, Inselspital, University of Bern, Bern, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jhep.2003.10.027DOI Listing
February 2004

Hyperdynamic circulation in liver cirrhosis: desensitization of vasoconstrictive receptors by G protein-coupled receptor kinases.

Med Hypotheses 2004 ;62(1):82-5

Department of Clinical Pharmacology, University of Bern, Murtenstrasse 35, Bern 3010, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0306-9877(03)00311-6DOI Listing
September 2004