David Schiff

David Schiff

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David Schiff

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Tumor pharmacokinetics and pharmacodynamics of the CDK4/6 inhibitor ribociclib in patients with recurrent glioblastoma.

J Neurooncol 2019 Sep 9;144(3):563-572. Epub 2019 Aug 9.

Department of Neurology, Division of Neuro-Oncology, University of Virginia Health System, P.O. Box 800432, Charlottesville, VA, 22908, USA.

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http://link.springer.com/10.1007/s11060-019-03258-0
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http://dx.doi.org/10.1007/s11060-019-03258-0DOI Listing
September 2019

Increased intratumoral infiltration in IDH wild-type lower-grade gliomas observed with diffusion tensor imaging.

J Neurooncol 2019 Sep 17. Epub 2019 Sep 17.

Department of Radiology, University of Virginia, Charlottesville, VA, 22908, USA.

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http://dx.doi.org/10.1007/s11060-019-03291-zDOI Listing
September 2019

Oligodendroglioma confers higher risk of radiation necrosis.

J Neurooncol 2019 Sep 23. Epub 2019 Sep 23.

Department of Neurology, Division of Neuro-Oncology, University of Virginia Health System, P.O. Box 800432, Charlottesville, VA, 22908, USA.

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http://dx.doi.org/10.1007/s11060-019-03297-7DOI Listing
September 2019

Multimodality Therapy of Patients with Refractory Meningiomas.

Curr Treat Options Oncol 2019 May 9;20(6):50. Epub 2019 May 9.

Division of Neuro-Oncology, School of Medicine, University of Virginia, PO Box 800432, Charlottesville, VA, 22908, USA.

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http://dx.doi.org/10.1007/s11864-019-0648-zDOI Listing
May 2019

FDG PET/MRI Coregistration Helps Predict Response to Gamma Knife Radiosurgery in Patients With Brain Metastases.

AJR Am J Roentgenol 2019 Feb 13;212(2):425-430. Epub 2018 Nov 13.

8 Department of Neurology, Neuro-Oncology Center, University of Virginia, Charlottesville, VA.

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http://dx.doi.org/10.2214/AJR.18.20006DOI Listing
February 2019

Lower-grade gliomas: the wrong target for bevacizumab.

Neuro Oncol 2018 11;20(12):1559-1560

Neuro-Oncology Department, The MD Anderson Cancer Center, Houston, Texas.

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http://dx.doi.org/10.1093/neuonc/noy165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231203PMC
November 2018

Preface.

Handb Clin Neurol 2018 ;149:ix

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http://dx.doi.org/10.1016/B978-0-12-811161-1.09988-6DOI Listing
September 2018

Improved molecular karyotyping in glioblastoma.

Mutat Res 2018 09 8;811:16-26. Epub 2018 Jul 8.

Department of Biochemistry and Molecular Genetics, University of Virginia, School of Medicine, Charlottesville, VA, United States; Department of Neuroscience, University of Virginia, School of Medicine, Charlottesville, VA, United States; Center for Public Health Genomics, University of Virginia, School of Medicine, Charlottesville, VA, United States; Center for Brain Immunology and Glia, University of Virginia, School of Medicine, Charlottesville, VA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mrfmmm.2018.06.002DOI Listing
September 2018

Neurologic and Medical Management of Brain Tumors.

Neurol Clin 2018 08 29;36(3):449-466. Epub 2018 May 29.

Division of Neuro-Oncology, University of Virginia Health System, 1300 Jefferson Park Avenue, West Complex, Room 6225, Charlottesville, VA 22903-0156, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ncl.2018.04.004DOI Listing
August 2018

Epidural and intramedullary spinal metastasis: clinical features and role of fractionated radiotherapy.

Handb Clin Neurol 2018 ;149:227-238

Departments of Neurology, Neurological Surgery and Medicine, University of Virginia, Charlottesville, VA, United States.

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http://dx.doi.org/10.1016/B978-0-12-811161-1.00015-3DOI Listing
July 2018

Variable response of CNS hemangioblastomas to Pazopanib in a single patient with von Hippel-Lindau disease: Case report.

J Clin Neurosci 2018 Apr 1;50:154-156. Epub 2018 Feb 1.

Department of Neurological Surgery, University of Virginia Health Science Center, Charlottesville, VA, United States.

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http://dx.doi.org/10.1016/j.jocn.2018.01.040DOI Listing
April 2018

Neurological complications of new chemotherapy agents.

Neuro Oncol 2018 01;20(1):24-36

Department of Neurology, University of Virginia, Charlottesville, Virginia.

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http://academic.oup.com/neuro-oncology/article/20/1/24/38711
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http://dx.doi.org/10.1093/neuonc/nox115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5761528PMC
January 2018

Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients naive to antiangiogenic therapy.

Neuro Oncol 2018 01;20(2):249-258

Center for Neuro-Oncology, Dana-Farber/Brigham & Women's Cancer Center, Boston, Massachusetts (P.Y.W, J.D.); The University of Texas MD Anderson Cancer Center, Houston, Texas (J.dG.); University of California, San Francisco, Helen Diller Cancer Center Building, San Francisco, California (M.D.P.); Duke University, Durham, North Carolina (D.A.R., A.D.); Neuro-Oncology Center, University of Virginia Health System, Charlottesville, Virginia (D.S.); University of Washington, Department of Neurology, Fred Hutchinson Cancer Research Center, Seattle, Washington (M.C.); Henry Ford Health System, Detroit, Michigan (T.M.); Exelixis, South San Francisco, California (J.H., J.P., R.W.); The Ronald Reagan UCLA Medical Center, Los Angeles, California (T.F.C.).

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http://dx.doi.org/10.1093/neuonc/nox154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777496PMC
January 2018

Phase II study of cabozantinib in patients with progressive glioblastoma: subset analysis of patients with prior antiangiogenic therapy.

Neuro Oncol 2018 01;20(2):259-267

The Ronald Reagan UCLA Medical Center, Los Angeles, California (T.F.C.); Center for Neuro-Oncology, Dana-Farber/Brigham & Women's Cancer Center, Boston, Massachusetts (P.Y.W., J.D.); The University of Texas MD Anderson Cancer Center, Houston, Texas (J.dG.); University of California San Francisco, San Francisco, California (M.D.P.); Duke University, Durham, North Carolina (D.A.R., A.D.); Neuro-Oncology Center, University of Virginia Health System, Charlottesville, Virginia (D.S.); University of Washington, Department of Neurology, Fred Hutchinson Cancer Research Center, Seattle, Washington (M.C.); Henry Ford Health System, Detroit, Michigan (T.M.); Exelixis, South San Francisco, California (J.P., J.H., R.W.).

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http://dx.doi.org/10.1093/neuonc/nox151DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777491PMC
January 2018

The siren song of bevacizumab: swan song or clarion call?

Neuro Oncol 2018 01;20(2):147-148

Center for Neuro-Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1093/neuonc/nox244DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777485PMC
January 2018

Low-grade Gliomas.

Authors:
David Schiff

Continuum (Minneap Minn) 2017 Dec;23(6, Neuro-oncology):1564-1579

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http://Insights.ovid.com/crossref?an=00132979-201712000-0000
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http://dx.doi.org/10.1212/CON.0000000000000537DOI Listing
December 2017

An alternative to radiotherapy in consolidation of brain lymphoma.

Authors:
David Schiff

Lancet Haematol 2017 11 17;4(11):e498-e499. Epub 2017 Oct 17.

University of Virginia Neuro-Oncology Center, Hospital West, Room 6225, Jefferson Park Avenue, Charlottesville, VA 22908-0432, USA. Electronic address:

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http://dx.doi.org/10.1016/S2352-3026(17)30197-7DOI Listing
November 2017

Benefit with adjuvant chemotherapy in anaplastic astrocytoma.

Authors:
David Schiff

Lancet 2017 10 8;390(10103):1625-1626. Epub 2017 Aug 8.

Neuro-Oncology Center, Hospital West, Room 6225, Charlottesville, VA 22908, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01406736173147
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http://dx.doi.org/10.1016/S0140-6736(17)31477-0DOI Listing
October 2017

Regression of an intramedullary spinal cord metastasis with a checkpoint inhibitor: a case report.

CNS Oncol 2017 10 16;6(4):275-280. Epub 2017 Oct 16.

Department of Neurology, Division of Neuro-Oncology, University of Virginia, Charlottesville, VA 22908 USA.

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http://dx.doi.org/10.2217/cns-2017-0007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004890PMC
October 2017

FDG PET/MR Imaging Coregistration Helps Predict Survival in Patients with Glioblastoma and Radiologic Progression after Standard of Care Treatment.

Radiology 2017 05 19;283(2):508-514. Epub 2016 Oct 19.

From the Department of Radiology (C.L.S., L.F., P.K.R.), Department of Neurology, Neuro-Oncology Center (D.S.), and Department of Public Health Sciences (J.T.P.), University of Virginia, 1215 Lee St, Charlottesville, VA 22908.

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http://dx.doi.org/10.1148/radiol.2016161172DOI Listing
May 2017

How can we develop therapies for glioblastoma more efficiently? Randomized versus single-arm studies.

Neuro Oncol 2017 04;19(4):459-460

Department of Neurology, University of Virginia, Charlottesville, Virginia, USA.

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https://academic.oup.com/neuro-oncology/article-lookup/doi/1
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http://dx.doi.org/10.1093/neuonc/nox041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5464309PMC
April 2017

Geographically Remote Cerebral Venous Sinus Thrombosis in Patients with Intracranial Tumors.

World Neurosurg 2017 Feb 24;98:555-562. Epub 2016 Nov 24.

Department of Neurosurgery, University of Virginia, Charlottesville, Virginia, USA. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2016.11.084DOI Listing
February 2017

Seizure control as a new metric in assessing efficacy of tumor treatment in low-grade glioma trials.

Neuro Oncol 2017 01 20;19(1):12-21. Epub 2016 Sep 20.

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York (E.K.A., L.M.D.); Department of Neurology, University of Washington, Seattle, Washington (M.C.); Department of Neurology, University of Virginia, Charlottesville, Virginia (D.S.); Department of Neurology, VUmc Cancer Center, Amsterdam, Netherlands (J.C.R.); Department of Family Health, University of Texas Health Science Center, Houston, Texas (T.S.A.); Department of Neuro-Oncology, City of Health and Science Hospital, Torino, Italy (R.R.); Center for Neuro-Oncology, Dana-Farber Cancer Institute/ Brigham and Women's Center, Boston, Massachusetts (P.W.); Department of Neurology, University Hospital Zurich, Zurich, Switzerland (M.W.); Department of Neurology, Leiden University Medical Center, The Hague, Netherlands (J.A.F.K.); Department of Neurosurgery, Wayne State University, Detroit, Michigan (S.M.); Department of Neurosurgery, Kyoto University School of Graduate Medicine, Kyoto, Japan (Y.A.); Department of Neurology, Southern Illinois University School of Medicine, Springfield, Illinois (A.C.); Department of Epilepsy and Surgery Center, Cleveland Clinic, Cleveland, Ohio (J.G.-M.); Department of Neurology, London Health Sciences Center, London, Ontario, Canada (D.R.M.); Department of Neurosurgery, Saitama Medical University, Saitama, Japan (R.N.); Department of Neurology, Wayne State University School of Medicine, Detroit, Michigan (A.S.); Service Neurologie Mazarin, CHU Pitie-Salpetriere, Paris, France (C.J.V.); Department of Neurology, University of Alabama, Birmingham, Alabama (P.W.); Department of Neuro-Oncology, Brain Tumor Center, Erasmus MC Cancer Institute, Rotterdam, Netherlands (M.J.v.d.B.).

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http://dx.doi.org/10.1093/neuonc/now190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5193028PMC
January 2017

Molecular profiling optimizes the treatment of low-grade glioma.

Authors:
David Schiff

Neuro Oncol 2016 12;18(12):1593-1594

University of Virginia Neuro-Oncology Center, Charlottesville, Virginia

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https://academic.oup.com/neuro-oncology/article-lookup/doi/1
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http://dx.doi.org/10.1093/neuonc/now262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744246PMC
December 2016

Culture conditions tailored to the cell of origin are critical for maintaining native properties and tumorigenicity of glioma cells.

Neuro Oncol 2016 10 21;18(10):1413-24. Epub 2016 Apr 21.

Department of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia (P.F.L., C.L., A.R.H., H.Z.); Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia (M.E.S., A.A., D.S.); Division of Neuropathology, Department of Pathology, Charlottesville, Virginia (M.B.S.L., J.W.M.); Department of Neurology, School of Medicine, University of Virginia, Charlottesville, Virginia (D.S.); Department of Pathology and Pathological Physiology, Center for Cancer Research, Zhejiang University School of Medicine, Zhejiang Diseases Proteomics Key Laboratory, Hangzhou, China (C.L.); Department of Biophysics and Center of Biotechnology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil (P.F.L., D.C.M., G.L.); Department of Neurosurgery, Changzheng Hospital, Second Affiliated Hospital of Second Military Medical University, Shanghai, China (H.H., Y.-C.L.); Department of Pathology, Xiang-ya Hospital, Central South University, Changsha, Hunan, China (H.-Y.Z.).

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http://dx.doi.org/10.1093/neuonc/now062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035523PMC
October 2016

Living in a material world: tumor-treating fields at the top of the charts.

Neuro Oncol 2016 08;18(8):1033-4

University of Virginia Neuro-Oncology Center, Charlottesville, Virginia (D. Schiff); Dana-Farber Cancer Institute, Boston, Massachusetts (D. Schrag).

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http://dx.doi.org/10.1093/neuonc/now138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933493PMC
August 2016

Redefining the Prevalence of Dural Involvement in Rosai-Dorfman Disease of the Central Nervous System.

World Neurosurg 2016 Jun 9;90:702.e13-702.e20. Epub 2016 Mar 9.

Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA.

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http://dx.doi.org/10.1016/j.wneu.2016.02.121DOI Listing
June 2016

PCV in low-grade gliomas: benefit from old drugs in an evolving disease entity.

Authors:
David Schiff

Neuro Oncol 2016 06;18(6):755-6

University of Virginia Neuro-Oncology Center, Charlottesville, Virginia.

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http://dx.doi.org/10.1093/neuonc/now098DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864269PMC
June 2016

Defining optimal initial therapy for primary CNS lymphoma.

Lancet Haematol 2016 05 6;3(5):e206-7. Epub 2016 Apr 6.

Radiation Oncology, Dana-Farber Cancer Institute, Havard T H Chan School of Public Health, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1016/S2352-3026(16)30021-7DOI Listing
May 2016

Quantifying the burden of primary central nervous system malignancy.

Authors:
David Schiff

Neuro Oncol 2016 Jan 20;18(1):5-6. Epub 2015 Nov 20.

University of Virginia Neuro-Oncology Center, Charlottesville, Virginia.

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http://dx.doi.org/10.1093/neuonc/nov287DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677424PMC
January 2016

Evolution of brain lesions in a patient with TREX1 cerebroretinal vasculopathy.

Neurology 2015 Nov;85(18):1633-4

From the University of Virginia (R.D., D.S., M.B.S.L., B.B.W.), Charlottesville; the UCLA School of Medicine (J.C.J.), Los Angeles, CA; and the Johns Hopkins University School of Medicine (D.D.L.), Baltimore, MD.

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http://dx.doi.org/10.1212/WNL.0000000000002092DOI Listing
November 2015

Improving Brain Tumor Research in Resource-Limited Countries: A Review of the Literature Focusing on West Africa.

Cureus 2015 Nov 3;7(11):e372. Epub 2015 Nov 3.

Department of Veterinary Physiology, Pharmacology and Biochemistry, University of Maiduguri, Nigeria.

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http://dx.doi.org/10.7759/cureus.372DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4671837PMC
November 2015

A phase II trial of everolimus, temozolomide, and radiotherapy in patients with newly diagnosed glioblastoma: NCCTG N057K.

Neuro Oncol 2015 Sep 18;17(9):1261-9. Epub 2014 Dec 18.

Mayo Clinic, Rochester, Minnesota (D.J.M., E.G., T.J.K., P.J.P., C.G., P.D.B., J.H.U., J.C.B., J.N.S.); Alliance Statistics and Data Center, Mayo Clinic, Rochester, Minnesota (S.K.A.); University of Virginia, Charlottesville, Virginia (D.S.); MD Anderson Cancer Center, Houston, Texas (P.D.B.); Sioux Community Cancer Consortium, Sioux Falls, South Dakota (S.M.); Mayo Clinic, Jacksonville, Florida (K.A.J.); Metro-Minnesota Community Clinical Oncology Program, St. Louis Park, Minnesota (P.J.F.); Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts (K.L.L.); Department of Medical Oncology, Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts (K.L.L.).

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http://dx.doi.org/10.1093/neuonc/nou328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4588750PMC
September 2015

Dasatinib in recurrent glioblastoma: failure as a teacher.

Neuro Oncol 2015 Jul 10;17(7):910-1. Epub 2015 May 10.

University of Virginia Neuro-Oncology Center, Charlottesville, Virginia (D.S.); Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota (J.S.).

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http://dx.doi.org/10.1093/neuonc/nov086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762007PMC
July 2015

Phase II study of panobinostat in combination with bevacizumab for recurrent glioblastoma and anaplastic glioma.

Neuro Oncol 2015 Jun 7;17(6):862-7. Epub 2015 Jan 7.

Dana-Farber/Brigham and Women's Cancer Center, Harvard Medical School, Boston, Massachusetts (E.Q.L., D.A.R., A.D.N., L.N., R.B., M.L.R., K.H., C.M., K.H.S., S.C.G., B.W., K.L.L., P.Y.W.); University of Virginia, Charlottesville, Virginia (D.S.); University of Pittsburgh, Pittsburgh, Pennsylvania (J.D.); Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts (A.S.C., T,T.B., A.M.); Central DuPage Hospital, Warrenville, Illinois (S.A.G.); Northwestern University, Chicago, Illinois (J.J.R.).

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http://neuro-oncology.oxfordjournals.org/content/17/6/862.fu
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http://neuro-oncology.oxfordjournals.org/cgi/doi/10.1093/neu
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http://dx.doi.org/10.1093/neuonc/nou350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483124PMC
June 2015

MicroRNA-608 and microRNA-34a regulate chordoma malignancy by targeting EGFR, Bcl-xL and MET.

PLoS One 2014 12;9(3):e91546. Epub 2014 Mar 12.

Departments of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, Virginia, United States of America; Department of Neurology, University of Virginia, Charlottesville, Virginia, United States of America; Cancer Center, University of Virginia, Charlottesville, Virginia, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0091546PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951453PMC
May 2015

Medical management of brain tumors and the sequelae of treatment.

Neuro Oncol 2015 Apr 30;17(4):488-504. Epub 2014 Oct 30.

Neuro-Oncology Center, University of Virginia Medical Center, Charlottesville, Virginia (D.S.); Center for Neuro-Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts (E.Q.L., L.N., A.D.N., D.A.R., P.Y.W.).

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http://dx.doi.org/10.1093/neuonc/nou304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483077PMC
April 2015

Low-grade gliomas.

Authors:
David Schiff

Continuum (Minneap Minn) 2015 Apr;21(2 Neuro-oncology):345-54

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http://dx.doi.org/10.1212/01.CON.0000464174.88687.79DOI Listing
April 2015

Primary CNS lymphoma: a landmark trial and the next steps.

Neurology 2015 Mar 25;84(12):1194-5. Epub 2015 Feb 25.

From the Departments of Neurology and Neurosurgery (E.A.N.), Oregon Health & Science University, Portland; the Portland Veterans Affairs Medical Center (E.A.N.), OR; and the University of Virginia Neuro-Oncology Center (D.S.), Charlottesville.

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http://dx.doi.org/10.1212/WNL.0000000000001407DOI Listing
March 2015

Much debated controversies of diffuse low-grade gliomas.

Neuro Oncol 2015 Mar;17(3):323-6

Division of Neurosurgery, University Health Network, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada (G.Z., O.H.K.); Division of Neurosurgery, Cleveland Clinic, Cleveland, Ohio (M.V.); Division of Neuro-Oncology, University of Virginia Medical Center, Charlottesville, Virginia (D.S.).

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http://dx.doi.org/10.1093/neuonc/nou368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483107PMC
March 2015

Phase 2 study of CT-322, a targeted biologic inhibitor of VEGFR-2 based on a domain of human fibronectin, in recurrent glioblastoma.

Invest New Drugs 2015 Feb 13;33(1):247-53. Epub 2014 Nov 13.

University of Virginia Neuro-Oncology Center, Box 800432, Charlottesville, VA, 22908-0432, USA,

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http://link.springer.com/10.1007/s10637-014-0186-2
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http://dx.doi.org/10.1007/s10637-014-0186-2DOI Listing
February 2015

Phase II trial of sunitinib for recurrent and progressive atypical and anaplastic meningioma.

Neuro Oncol 2015 Jan 6;17(1):116-21. Epub 2014 Aug 6.

Department of Neurology, Memorial Sloan Kettering Cancer Center, New York, New York (T.J.K., S.K., A.B.L., C.P.N., L.M.D., I.G., L.E.A., A.O.); Center for Neuro-Oncology, Dana-Farber Cancer Institute/Brigham and Women's Center, Boston, Massachusetts (P.W., K.L., S.H., A.N., J.D., E.Q.L.); Department of Neurology, University of Virginia, Charlottesville, Virginia (D.S., B.P.); Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts (S.R.P., T.B.).

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http://dx.doi.org/10.1093/neuonc/nou148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483051PMC
January 2015

Treatment considerations for MGMT-unmethylated glioblastoma.

Curr Neurol Neurosci Rep 2015 Jan;15(1):507

Department of Neurological Surgery, University of California, San Francisco, CA, USA.

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http://link.springer.com/10.1007/s11910-014-0507-z
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http://dx.doi.org/10.1007/s11910-014-0507-zDOI Listing
January 2015

Therapeutic decision making in patients with newly diagnosed low grade glioma.

Curr Treat Options Oncol 2014 Dec;15(4):529-38

Department of Neurosurgery, University of Virginia Medical Center, Charlottesville, VA, 22903, USA,

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http://link.springer.com/10.1007/s11864-014-0304-6
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http://dx.doi.org/10.1007/s11864-014-0304-6DOI Listing
December 2014

Recursive partitioning analysis of prognostic variables in newly diagnosed anaplastic oligodendroglial tumors.

Neuro Oncol 2014 Nov 4;16(11):1541-6. Epub 2014 Jul 4.

Departments of Neurology (A.B.L., F.M.I., L.E.A., L.M.D.), Pathology (S.C.J., M.K.R.), Epidemiology & Biostatistics (A.S.R., K.S.P.), and the Brain Tumor Center, Memorial Sloan-Kettering Cancer Center, New York, New York; University of California, Los Angeles, Los Angeles, California (T.F.C.); Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas (K.D.A., A.L.R.); Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts (A.F.E., D.N.L.); NorthShore University Health System, Evanston Hospital Kellogg Cancer Center, University of Chicago, Pritzker School of Medicine, Evanston, Illinois (N.A.P.); London Regional Cancer Program, London, Ontario, Canada (B.J.F.); Barrow Neurological Institute, Phoenix, Arizona (L.S.A.); University of Calgary, Calgary, Alberta, Canada (J.G.C., G.B.R.U.); Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, Massachusetts (P.Y.W.); Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Children's Hospital Boston, Brigham and Women's Hospital, Boston, Massachusetts (K.L.L.); University of Virginia Health System, Charlottesville, Virginia (D.S.); University of Wisconsin, Madison, Wisconsin (H.I.R., B.G.R.); University of Washington, Fred Hutchinson Cancer Research Center and Seattle Cancer Care Alliance, Seattle, Washington (M.C.C.); Princess Margaret Hospital, Toronto, Ontario, Canada (W.P.M.); Albany Medical Center, Albany, New York (S.A.W.); Kaiser Permanente-Los Angeles Medical Center, Los Angeles, California (R.M.G.); Clemenceau Medical Center, Beirut, Lebanon and Université Saint-Esprit de Kaslik, Byblos, Lebanon (F.G.K.).

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http://dx.doi.org/10.1093/neuonc/nou083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201067PMC
November 2014

Effect of neoadjuvant temozolomide upon volume reduction and resection of diffuse low-grade glioma.

J Neurooncol 2014 Oct 20;120(1):155-61. Epub 2014 Jul 20.

Division of Neuro-Oncology, Department of Neurology, University of Virginia, Hospital West Room 6225, PO Box 800432, Charlottesville, VA, 22908, USA.

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http://dx.doi.org/10.1007/s11060-014-1538-7DOI Listing
October 2014

Comment: can APOE genotyping predict cognitive damage from brain tumor therapy?

Authors:
David Schiff

Neurology 2014 Jul 18;83(4):326. Epub 2014 Jun 18.

From the Departments of Neurology, Neurological Surgery, and Medicine (Hematology/Oncology), University of Virginia Health System, Charlottesville.

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http://dx.doi.org/10.1212/WNL.0000000000000632DOI Listing
July 2014

Historical benchmarks for medical therapy trials in surgery- and radiation-refractory meningioma: a RANO review.

Neuro Oncol 2014 Jun 4;16(6):829-40. Epub 2014 Feb 4.

Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, New York (T.K.); Department of Radiation Oncology, University of California, San Francisco, San Francisco, California (I.B.); Department of Neurology, University of Washington, Seattle, Washington (M.C.); Department of Neurosurgery, University of California, San Francisco, San Francisco, California (M.D.); Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, New York (K.P.); Department of Neurology, Northwestern University, Chicago, Illinois (J.R.); Department of Radiation Oncology, Gamma West Cancer Services, Salt Lake City, Utah (L.R.); Department of Neurology, University of Virginia, Charlottesville, Virginia (D.S.); Department of Neuro-Oncology, Cleveland Clinic, Cleveland, Ohio (M.V.); Division of Radiation Oncology, Geneva University Hospital, Geneva, Switzerland (D.W.); Center for Neuro-Oncology, Dana-Farber Cancer Institute/Brigham and Women's Center, Boston, Massachsetts (P.W.).

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https://academic.oup.com/neuro-oncology/article-lookup/doi/1
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http://dx.doi.org/10.1093/neuonc/not330DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022224PMC
June 2014

Thrombosis in brain tumors.

Semin Thromb Hemost 2014 Apr 5;40(3):325-31. Epub 2014 Mar 5.

Division of Neurology, Sunnybrook Health Science and Odette Cancer Centre, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1055/s-0034-1370791DOI Listing
April 2014

microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma.

Cancer Res 2014 Mar 14;74(5):1541-53. Epub 2014 Jan 14.

Authors' Affiliations: Departments of Microbiology, Immunology and Cancer Biology, Neurology, and Cancer Center, University of Virginia, Charlottesville, Virginia; Leeds Institute of Cancer and Pathology, University of Leeds, Leeds, United Kingdom; and Department of Neurosurgery, Brigham and Women's Hospital, Boston, Massachusetts.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-13-1449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3947487PMC
March 2014

Multimodal MR imaging model to predict tumor infiltration in patients with gliomas.

Neuroradiology 2014 Feb 15;56(2):107-15. Epub 2013 Dec 15.

University of Virginia Health Systems, Division of Neuroradiology, Department of Radiology and Medical Imaging, PO Box 800170, FedEx:1215 Lee Street-New Hospital, Charlottesville, VA, 22908, USA,

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http://link.springer.com/10.1007/s00234-013-1308-9
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http://dx.doi.org/10.1007/s00234-013-1308-9DOI Listing
February 2014

A randomized trial of bevacizumab for newly diagnosed glioblastoma.

N Engl J Med 2014 Feb;370(8):699-708

From the University of Texas M.D. Anderson Cancer Center (M.R.G., T.S.A., J.S.W., P.D.B., I.W.T.-L., E.P.S., K.D.A.) and the University of Texas Health Science Center School of Nursing (T.S.A.), Houston; American College of Radiology (J.J.D., S.P., M.W.) and Thomas Jefferson University (M.W.-W.) - both in Philadelphia; the University of Chicago, Chicago (J.J.D.); Tel-Aviv Medical Center, Tel Aviv, Israel (D.T.B.); Cleveland Clinic, Cleveland (M.A.V.); the University of Utah, Salt Lake City (H.C.); Ohio State University, Columbus (A.C.); University of Wisconsin, Madison (R.J.); Mayo Clinic, Jacksonville, FL (K.A.J.); University of Virginia, Charlottesville (D.S.); Southeast Cancer Control Consortium, Winston-Salem, NC (V.W.S.); Barrow Neurologic Institute, Phoenix, AZ (D.G.B.); Emory University, Atlanta (W.J.C.); and the University of Maryland, Baltimore (M.P.M.).

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http://dx.doi.org/10.1056/NEJMoa1308573DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201043PMC
February 2014

microRNA-34a promotes DNA damage and mitotic catastrophe.

Cell Cycle 2013 Nov 19;12(22):3500-11. Epub 2013 Sep 19.

Department of Microbiology, Immunology and Cancer Biology; University of Virginia; Charlottesville, VA USA; Aging-Cancer Interface Group; LDS Medical Center; St. Petersburg, Russia.

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http://dx.doi.org/10.4161/cc.26459DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906336PMC
November 2013

Rituximab, methotrexate, procarbazine, and vincristine followed by consolidation reduced-dose whole-brain radiotherapy and cytarabine in newly diagnosed primary CNS lymphoma: final results and long-term outcome.

J Clin Oncol 2013 Nov 7;31(31):3971-9. Epub 2013 Oct 7.

Patrick G. Morris, Denise D. Correa, Joachim Yahalom, Anne S. Reiner, Kathy Panageas, Sasan Karimi, Richard Curry, Gaurav Shah, Lauren E. Abrey, Lisa M. DeAngelis, and Antonio Omuro, Memorial Sloan-Kettering Cancer Center; Rose K. Lai, Columbia University, New York, NY; Jeffrey J. Raizer and Sean Grimm, Northwestern University, Chicago, IL; David Schiff, University of Virginia, Charlottesville, VA; and Barbara Grant, University of Vermont, Burlington, VT.

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http://dx.doi.org/10.1200/JCO.2013.50.4910DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569679PMC
November 2013

Primary leptomeningeal lymphoma: International Primary CNS Lymphoma Collaborative Group report.

Neurology 2013 Nov 9;81(19):1690-6. Epub 2013 Oct 9.

From the Massachusetts General Hospital (J.W.T., T.B., R.A.B.), Boston; Mayo Clinic (E.P.F., B.P.O.), Rochester, MN; Hadassah Hebrew University Medical Center (T.S.), Jerusalem, Israel; Memorial Sloan-Kettering (A.O., L.D.), New York, NY; Yale University (J.B.), New Haven, CT; Saitama Medical University (R.N.), Japan; Kings College Hospital (F.P.), London, UK; University of Washington (M.C.), Seattle; LOC National Expert Center (K.H.-X., A.G.-A.), APHP, UPMC, Pitie-Salpetriere, Paris; Centre Leon Berard (J.-Y.B.), Lyon, France; Campus Benjamin Franklin (A.K.), Charite Universitätsmedizin Berlin, Germany; Department of Biostatistics (R.A.B.), Harvard School of Public Health, Boston, MA; and University of Virginia (M.-B.S.L., D.S.), Charlottesville.

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http://dx.doi.org/10.1212/01.wnl.0000435302.02895.f3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3812109PMC
November 2013

Neuro-oncology: Five new things.

Neurol Clin Pract 2013 Aug;3(4):326-333

Departments of Neurology and Neuroscience, University of Virginia School of Medicine, Charlottesville.

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http://dx.doi.org/10.1212/CPJ.0b013e3182a1ba35DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787111PMC
August 2013

The p53-microRNA-34a axis regulates cellular entry receptors for tumor-associated human herpes viruses.

Med Hypotheses 2013 Jul 2;81(1):62-7. Epub 2013 May 2.

Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1016/j.mehy.2013.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676726PMC
July 2013

A model for the regulation of T-type Ca(2+) channels in proliferation: roles in stem cells and cancer.

Expert Rev Anticancer Ther 2013 May;13(5):589-95

Tau Therapeutics, LLC, 600 E. Water Street, Charlottesville, VA 22902, USA.

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http://dx.doi.org/10.1586/era.13.34DOI Listing
May 2013

Oncogenic effects of miR-10b in glioblastoma stem cells.

J Neurooncol 2013 Apr 10;112(2):153-63. Epub 2013 Jan 10.

Departments of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA.

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http://dx.doi.org/10.1007/s11060-013-1047-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3609924PMC
April 2013

Phase I study of GRN1005 in recurrent malignant glioma.

Clin Cancer Res 2013 Mar 24;19(6):1567-76. Epub 2013 Jan 24.

Center for Neuro-Oncology, Dana Farber/Brigham & Women's Cancer Center, Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-2481DOI Listing
March 2013

Hepatocyte growth factor sensitizes brain tumors to c-MET kinase inhibition.

Clin Cancer Res 2013 Mar 5;19(6):1433-44. Epub 2013 Feb 5.

Department of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, Virginia 22908, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-12-2832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602223PMC
March 2013

Spinal cord compression.

Curr Treat Options Neurol 2012 Aug;14(4):391-401

University of Virginia Neuro-Oncology Center, Box 800432, Charlottesville, VA, 22908-0432, USA.

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http://dx.doi.org/10.1007/s11940-012-0176-7DOI Listing
August 2012

Comments.

Neurosurgery 2012 Jul;71(1):79

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July 2012

Angiogenic inhibition in high-grade gliomas: past, present and future.

Expert Rev Neurother 2012 Jun;12(6):733-47

Department of Neurology, Division of Neuro-Oncology, University of Virginia, Charlottesville, VA 22908-0432, USA.

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http://dx.doi.org/10.1586/ern.12.53DOI Listing
June 2012