Publications by authors named "David S Ziegler"

66Publications

Immune profiling of pediatric solid tumors.

J Clin Invest 2020 Jul;130(7):3391-3402

Cancer Immunology Program, Peter MacCallum Cancer Center, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1172/JCI137181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324195PMC
July 2020

Driving innovation through collaboration: development of clinical annotation datasets for brain cancer biobanking.

Neurooncol Pract 2020 Jan 27;7(1):31-37. Epub 2019 Aug 27.

Brain Cancer Biobanking Australia, National Health and Medical Research Council Clinical Trials Centre, The University of Sydney, NSW, Australia.

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http://dx.doi.org/10.1093/nop/npz036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104879PMC
January 2020

Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.

Authors:
Matthew Clarke Alan Mackay Britta Ismer Jessica C Pickles Ruth G Tatevossian Scott Newman Tejus A Bale Iris Stoler Elisa Izquierdo Sara Temelso Diana M Carvalho Valeria Molinari Anna Burford Louise Howell Alex Virasami Amy R Fairchild Aimee Avery Jane Chalker Mark Kristiansen Kelly Haupfear James D Dalton Wilda Orisme Ji Wen Michael Hubank Kathreena M Kurian Catherine Rowe Mellissa Maybury Stephen Crosier Jeffrey Knipstein Ulrich Schüller Uwe Kordes David E Kram Matija Snuderl Leslie Bridges Andrew J Martin Lawrence J Doey Safa Al-Sarraj Christopher Chandler Bassel Zebian Claire Cairns Rachael Natrajan Jessica K R Boult Simon P Robinson Martin Sill Ira J Dunkel Stephen W Gilheeney Marc K Rosenblum Debbie Hughes Paula Z Proszek Tobey J Macdonald Matthias Preusser Christine Haberler Irene Slavc Roger Packer Ho-Keung Ng Shani Caspi Mara Popović Barbara Faganel Kotnik Matthew D Wood Lissa Baird Monika Ashok Davare David A Solomon Thale Kristin Olsen Petter Brandal Michael Farrell Jane B Cryan Michael Capra Michael Karremann Jens Schittenhelm Martin U Schuhmann Martin Ebinger Winand N M Dinjens Kornelius Kerl Simone Hettmer Torsten Pietsch Felipe Andreiuolo Pablo Hernáiz Driever Andrey Korshunov Lotte Hiddingh Barbara C Worst Dominik Sturm Marc Zuckermann Olaf Witt Tabitha Bloom Clare Mitchell Evelina Miele Giovanna Stefania Colafati Francesca Diomedi-Camassei Simon Bailey Andrew S Moore Timothy E G Hassall Stephen P Lowis Maria Tsoli Mark J Cowley David S Ziegler Matthias A Karajannis Kristian Aquilina Darren R Hargrave Fernando Carceller Lynley V Marshall Andreas von Deimling Christof M Kramm Stefan M Pfister Felix Sahm Suzanne J Baker Angela Mastronuzzi Andrea Carai Maria Vinci David Capper Sergey Popov David W Ellison Thomas S Jacques David T W Jones Chris Jones

Cancer Discov 2020 Jul 1;10(7):942-963. Epub 2020 Apr 1.

Division of Molecular Pathology, Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1158/2159-8290.CD-19-1030DOI Listing
July 2020

Translating palbociclib to the clinic for DIPG - What is truly achievable?

EBioMedicine 2019 07 22;45:22. Epub 2019 Jun 22.

Children's Cancer Institute, UNSW, Sydney, Australia; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.06.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6642255PMC
July 2019

Piloting a parent and patient decision aid to support clinical trial decision making in childhood cancer.

Psychooncology 2019 07 11;28(7):1520-1529. Epub 2019 Jun 11.

School of Women's and Children's Health, UNSW Sydney, Kensington, New South Wales, Australia.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/pon.5109
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http://dx.doi.org/10.1002/pon.5109DOI Listing
July 2019

Predictors of Success of Phase II Pediatric Oncology Clinical Trials.

Oncologist 2019 08 26;24(8):e765-e774. Epub 2019 Feb 26.

Children's Cancer Institute, University of New South Wales, Randwick, Australia

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http://dx.doi.org/10.1634/theoncologist.2017-0666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693728PMC
August 2019

Oral malignant gastrointestinal neuroectodermal tumour with junctional component mimicking mucosal melanoma.

Pathology 2018 Oct 31;50(6):648-653. Epub 2018 Aug 31.

Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, NSW, Australia; Sydney Medical School, The University of Sydney, Sydney, NSW, Australia; Melanoma Institute Australia, The University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/j.pathol.2018.07.002DOI Listing
October 2018

Unresectable VIP-secreting neuroblastoma: Efficacy of debulking and steroids for symptom control.

Pediatr Blood Cancer 2018 12 19;65(12):e27358. Epub 2018 Jul 19.

Kids Cancer Centre, Sydney Children's Hospital, Randwick, New South Wales, Australia.

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http://dx.doi.org/10.1002/pbc.27358DOI Listing
December 2018

Treatment with nitric oxide in the neonatal intensive care unit is associated with increased risk of childhood cancer.

Acta Paediatr 2018 12 27;107(12):2092-2098. Epub 2018 Jun 27.

School of Women's and Children's Health, University of New South Wales, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/apa.14436DOI Listing
December 2018

Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

J Clin Oncol 2018 07 10;36(19):1963-1972. Epub 2018 May 10.

Lindsey M. Hoffman and Nicholas K. Foreman, University of Colorado Denver; Lindsey M. Hoffman and Nicholas K. Foreman, Children's Hospital Colorado, Aurora, CO; Sophie E.M. Veldhuijzen van Zanten, Esther Hulleman, Gertjan J.L. Kaspers, Esther Sanchez, and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; William P. Vandertop, Academy of Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Niclas Colditz, Marion Hoffmann, Brigitte Bison, Monika Warmuth-Metz, and Christof M. Kramm, University Medical Center Goettingen, Goettingen; Torsten Pietsch and Gerrit H. Gielen, University of Bonn Medical Center, Bonn; David T.W. Jones, Dominik Sturm, Stefan M. Pfister, and Elke Pfaff, German Cancer Research Center, Hopp-Children's Cancer Center at the Nationale Centrum für Tumorerkrankungen Heidelberg, and German Consortium for Translational Cancer Research; Dominik Sturm, Stefan M. Pfister, and Elke Pfaff, Heidelberg University Hospital, Heidelberg, Germany; Joshua Baugh, Brooklyn Chaney, Adam Lane, Christine Fuller, Nancy Yanez Escorza, Renee Doughman, Rachid Drissi, James Leach, Blaise Jones, and Maryam Fouladi, Cincinnati Children's Hospital Medical Center, Cincinnati; Emmett Broxson, Wright State University and The Children's Medical Center, Dayton, OH; Lili Miles, Nemours Children's Hospital, Orlando, FL; Cynthia Hawkins, Ute Bartels, and Eric Bouffet, The Hospital for Sick Children, Toronto, Ontario; Anne Sophie Carret, Centre Hospitalier Universitaire Sainte-Justine; Nada Jabado, McGill University, Montreal, Quebec, Canada; Stewart Goldman, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL; Sarah Leary, Seattle Children's Hospital, University of Washington and Fred Hutchinson Cancer Research Center, Seattle, WA; Roger Packer, Children's National Health System; Javad Nazarian, Children's National Medical Center, Washington, DC; Katherine E. Warren, National Cancer Institute, Bethesda, MD; Alberto Broniscer, St Jude Children's Research Hospital, Memphis, TN; Mark W. Kieran, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA; Jane Minturn, Children's Hospital of Philadelphia and The Perelman School of Medicine at the University of Pennsylvania, Philadelphia; Melanie Comito, The Pennsylvania State University, Hershey, PA; Chie-Schin Shih, Indiana University, Indianapolis, IN; Soumen Khatua, The University of Texas MD Anderson Cancer Center; Murali Chintagumpala, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX; Timothy Hassall, Lady Cilento Children's Hospital, Brisbane, Queensland; David S. Ziegler, Kids Cancer Centre, Sydney Children's Hospital, Randwick; David S. Ziegler, University of New South Wales, Sydney, New South Wales; Nicholas Gottardo and Hetal Dholaria, Princess Margaret Hospital for Children, Perth, Western Australia, Australia; Martin Benesch, Medical University of Graz, Graz, Austria; Nathalie Boddaert. Stephanie Puget, and Raphaël Calmon, Hôpital Necker Enfants Malades; Pascale Varlet, Hôpital Sainte-Anne, Université Paris V Descartes, Sorbonne Paris Cité, Paris; Géraldine Giraud, David Castel, and Jacques Grill, Gustave Roussy, Université Paris-Sud, Université Paris-Saclay, Villejuif, France; Géraldine Giraud, Uppsala University, Uppsala, Sweden; Chris Jones, The Institute of Cancer Research, Sutton; Darren Hargrave, Great Ormond Street Hospital, London; Guirish A. Solanki, Birmingham Women's and Children's Hospital, Birmingham; Simon Bailey, Great North Children's Hospital, Victoria Wing, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom; Piergiorgio Modena and Marzia Giagnacovo, Sant' Anna Como General Hospital, Como; Manila Antonelli, Sapienza University of Rome, Rome; Veronica Biassoni and Maura Massimino, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, Milan, Italy; Nicolas U. Gerber and Michael A. Grotzer, University Children's Hospital of Zurich, Zurich; André O. von Bueren, University Hospital of Geneva and University of Geneva, Geneva, Switzerland; and Filip Jadrijevic Cvrlje and Gertjan J.L. Kaspers, Children's Hospital Zagreb, Zagreb, Croatia.

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http://dx.doi.org/10.1200/JCO.2017.75.9308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075859PMC
July 2018

The Development of Delta: Using Agile to Develop a Decision Aid for Pediatric Oncology Clinical Trial Enrollment.

JMIR Res Protoc 2018 May 4;7(5):e119. Epub 2018 May 4.

Behavioural Sciences Unit, Kids Cancer Centre, Sydney Children's Hospital, Randwick, Australia.

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http://dx.doi.org/10.2196/resprot.9258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960036PMC
May 2018

Too many targets, not enough patients: rethinking neuroblastoma clinical trials.

Nat Rev Cancer 2018 06;18(6):389-400

Children's Cancer Institute Australia, Lowy Cancer Research Centre, UNSW Sydney, Kensington, NSW, Australia.

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http://www.nature.com/articles/s41568-018-0003-x
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http://dx.doi.org/10.1038/s41568-018-0003-xDOI Listing
June 2018

Targeted Doxorubicin-Loaded Bacterially Derived Nano-Cells for the Treatment of Neuroblastoma.

Mol Cancer Ther 2018 05 28;17(5):1012-1023. Epub 2018 Feb 28.

Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-0738DOI Listing
May 2018

Dual targeting of mitochondrial function and mTOR pathway as a therapeutic strategy for diffuse intrinsic pontine glioma.

Oncotarget 2018 Jan 8;9(7):7541-7556. Epub 2018 Jan 8.

Targeted Therapies Research Program, Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, New South Wales, Australia.

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http://www.oncotarget.com/fulltext/24045
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http://dx.doi.org/10.18632/oncotarget.24045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800923PMC
January 2018

Investigating the biology of relapsed acute leukemia: Proceedings of the Therapeutic Advances for Childhood Leukemia & Lymphoma (TACL) Consortium Biology Working Group.

Pediatr Hematol Oncol 2017 Sep - Oct;34(6-7):355-364. Epub 2017 Nov 30.

h Division of Pediatric Hematology and Oncology, Department of Pediatrics and OHSU Knight Cancer Institute , Oregon Health and Sciences University , Portland , OR , USA.

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https://www.tandfonline.com/doi/full/10.1080/08880018.2017.1
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http://dx.doi.org/10.1080/08880018.2017.1395937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6191173PMC
July 2018

Comprehensive Analysis of Hypermutation in Human Cancer.

Cell 2017 Nov 19;171(5):1042-1056.e10. Epub 2017 Oct 19.

Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.09.048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5849393PMC
November 2017

A novel somatic JAK2 kinase-domain mutation in pediatric acute lymphoblastic leukemia with rapid on-treatment development of LOH.

Cancer Genet 2017 Oct 31;216-217:86-90. Epub 2017 Jul 31.

Cancer Theme, South Australian Health & Medical Research Institute, Adelaide, SA, Australia; Discipline of Medicine, University of Adelaide, Adelaide, SA, Australia; Australian Genomic Health Alliance, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.cancergen.2017.07.008DOI Listing
October 2017

Genomic Insights into Diffuse Intrinsic Pontine Glioma.

Front Oncol 2017 28;7:57. Epub 2017 Mar 28.

Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Randwick, NSW, Australia; Kids Cancer Centre, Sydney Children's Hospital, Randwick, NSW, Australia.

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http://dx.doi.org/10.3389/fonc.2017.00057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5368268PMC
March 2017

Ganglioglioma Arising From Desmoplastic Medulloblastoma: A Case Report and Review of Literature.

Pediatrics 2017 Mar;139(3)

Kids Cancer Centre, Sydney Children's Hospital, Randwick, New South Wales, Australia; and.

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http://pediatrics.aappublications.org/lookup/doi/10.1542/ped
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http://dx.doi.org/10.1542/peds.2016-1403DOI Listing
March 2017

Polyamine Antagonist Therapies Inhibit Neuroblastoma Initiation and Progression.

Clin Cancer Res 2016 Sep 24;22(17):4391-404. Epub 2016 Mar 24.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1158/1078-0432.CCR-15-2539DOI Listing
September 2016

Case Report of Spontaneous Resolution of a Congenital Glioblastoma.

Pediatrics 2016 Apr 15;137(4). Epub 2016 Mar 15.

Kids Cancer Centre, Sydney Children's Hospital, High St, Randwick, Australia; School of Women's and Children's Health, University of New South Wales, Randwick, Australia

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http://dx.doi.org/10.1542/peds.2015-1241DOI Listing
April 2016

Never say never.

Authors:
David S Ziegler

J Clin Oncol 2015 Feb 5;33(5):518-20. Epub 2015 Jan 5.

From the Sydney Children's Hospital Kids Cancer Centre and University of New South Wales School of Women's and Children's Health, Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1200/JCO.2014.58.7717DOI Listing
February 2015

Outcomes in multifocal neuroblastoma as part of the neurocristopathy syndrome.

Pediatrics 2014 Aug;134(2):e611-6

Kids Cancer Centre, Sydney Children's Hospital, Randwick, New South Wales, Australia;School of Women's and Children's Health, Faculty of Medicine, University of New South Wales, Australia; and

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http://dx.doi.org/10.1542/peds.2013-3340DOI Listing
August 2014

Molecular profiling of childhood cancer: Biomarkers and novel therapies.

BBA Clin 2014 Jun 28;1:59-77. Epub 2014 Jun 28.

Children's Cancer Research Unit, Kids Research Institute, Westmead 2145, New South Wales, Australia ; The University of Sydney Discipline of Paediatrics and Child Health, The Children's Hospital at Westmead, Westmead 2145, New South Wales, Australia.

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http://dx.doi.org/10.1016/j.bbacli.2014.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633945PMC
June 2014

Antibody therapy for pediatric leukemia.

Front Oncol 2014 21;4:82. Epub 2014 Apr 21.

Kids Cancer Centre, Sydney Children's Hospital , Randwick, NSW , Australia ; School of Women and Children's Health, University of New South Wales , Randwick, NSW , Australia.

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http://journal.frontiersin.org/article/10.3389/fonc.2014.000
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http://dx.doi.org/10.3389/fonc.2014.00082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4000992PMC
June 2014

Polyamine pathway inhibition as a novel therapeutic approach to treating neuroblastoma.

Front Oncol 2012 16;2:162. Epub 2012 Nov 16.

Children's Cancer Institute Australia for Medical Research, Lowy Cancer Research Centre Sydney, NSW, Australia.

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http://dx.doi.org/10.3389/fonc.2012.00162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499881PMC
November 2012

Targeting the inhibitor of apoptosis proteins as a novel therapeutic strategy in medulloblastoma.

Mol Cancer Ther 2012 Dec 25;11(12):2654-63. Epub 2012 Sep 25.

Children's Cancer Institute Australia, Lowy Cancer Research Centre, University ofNewSouth Wales, Australia.

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http://dx.doi.org/10.1158/1535-7163.MCT-12-0352DOI Listing
December 2012

Neonatal Sweet syndrome: a potential marker of serious systemic illness.

Pediatrics 2012 May 16;129(5):e1353-9. Epub 2012 Apr 16.

Department of Immunology, Sydney Children's Hospital, Randwick, New South Wales, Australia.

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http://pediatrics.aappublications.org/content/pediatrics/129
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http://pediatrics.aappublications.org/cgi/doi/10.1542/peds.2
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http://dx.doi.org/10.1542/peds.2011-1854DOI Listing
May 2012

Australian Paediatric Surveillance Unit study of haemoglobinopathies in Australian children.

J Paediatr Child Health 2012 Apr 13;48(4):356-60. Epub 2011 Dec 13.

Sydney Children's Hospital, Randwick, Australia.

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http://dx.doi.org/10.1111/j.1440-1754.2011.02236.xDOI Listing
April 2012

Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins.

J Clin Invest 2008 Sep;118(9):3109-22

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1172/JCI34120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2491457PMC
September 2008

Anti-apoptosis mechanisms in malignant gliomas.

J Clin Oncol 2008 Jan;26(3):493-500

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Children's Hospital, Harvard Medical School, Boston, MA, USA.

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http://ascopubs.org/doi/10.1200/JCO.2007.13.9717
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http://dx.doi.org/10.1200/JCO.2007.13.9717DOI Listing
January 2008

Therapeutic targeting of apoptosis pathways in cancer.

Curr Opin Oncol 2008 Jan;20(1):97-103

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1097/CCO.0b013e3282f310f6DOI Listing
January 2008

Efficacy of vincristine and etoposide with escalating cyclophosphamide in poor-prognosis pediatric brain tumors.

Neuro Oncol 2006 Jan;8(1):53-9

Centre for Children's Cancer and Blood Disorders, Sydney Children's Hospital, High St., Randwick, NSW 2031, Australia.

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http://dx.doi.org/10.1215/S1522851705000463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1871918PMC
January 2006

Long-term survival following a phase I/II trial with VETOPEC for solid tumors in childhood.

J Pediatr Hematol Oncol 2006 Jan;28(1):40-2

Centre for Children's Cancer and Blood Disorders, Sydney Children's Hospital, Randwick, NSW, Australia.

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January 2006

Assessment and follow-up of suspected child abuse in preschool children with fractures seen in a general hospital emergency department.

J Paediatr Child Health 2005 May-Jun;41(5-6):251-5

Sydney Children's Hospital, Randwick, New South Wales, Australia.

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http://doi.wiley.com/10.1111/j.1440-1754.2005.00605.x
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http://dx.doi.org/10.1111/j.1440-1754.2005.00605.xDOI Listing
October 2005

Retinoic acid may increase the risk of bone marrow transplant nephropathy.

Pediatr Nephrol 2005 Apr 18;20(4):534-8. Epub 2005 Feb 18.

Department of Nephrology, Sydney Children's Hospital, Randwick, N.S.W., Australia.

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http://link.springer.com/10.1007/s00467-004-1775-7
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http://dx.doi.org/10.1007/s00467-004-1775-7DOI Listing
April 2005

Advances in childhood leukaemia: successful clinical-trials research leads to individualised therapy.

Med J Aust 2005 Jan;182(2):78-81

Centre for Children's Cancer and Blood Disorders, Sydney Children's Hospital, Randwick, NSW, Australia.

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January 2005

Throat clearing in asthma.

Authors:
David S Ziegler

N Engl J Med 2003 Jul;349(2):194-5; author reply 194-5

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July 2003