David S Schrump

David S Schrump

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David S Schrump

Publications by authors named "David S Schrump"

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MicroRNA-215-5p Treatment Suppresses Mesothelioma Progression via the MDM2-p53-Signaling Axis.

Mol Ther 2019 Sep 4;27(9):1665-1680. Epub 2019 Jun 4.

Thoracic Surgery Branch, National Cancer Institute, NIH, CCR and The Clinical Center, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2019.05.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731470PMC
September 2019

Severe Hepatotoxicity of Mithramycin Therapy Caused by Altered Expression of Hepatocellular Bile Transporters.

Mol Pharmacol 2019 Aug 7;96(2):158-167. Epub 2019 Jun 7.

Clinical Pharmacology Program (T.M.S., C.J.P., W.D.F.), Molecular Pharmacology Section (P.A.H., R.J.H., E.M.M., R.H.B., J.D.S., A.M.L., W.D.F.), Biostatistics and Data Management Section (M.Z., J.A.H., D.V.), Pediatric Oncology Branch (P.G., J.G., B.C.W.), Thoracic Surgery Branch, Center for Cancer Research, National Cancer Institute (D.S.S.), and Translational Hepatology Section (T.H.), Liver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland; and BioIVT, ADME-Tox Division, Durham, North Carolina (J.P.J., K.R.B.)

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http://dx.doi.org/10.1124/mol.118.114827DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6608607PMC
August 2019

Metadherin Is a Prognostic Apoptosis Modulator in Mesothelioma Induced via NF-κB-Mediated Signaling.

Transl Oncol 2019 Jun 1;12(6):859-870. Epub 2019 May 1.

Thoracic Surgery Branch, NCI, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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http://dx.doi.org/10.1016/j.tranon.2019.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500914PMC
June 2019

Analysis of circulating tumor DNA: The next paradigm shift in detection and treatment of lung cancer.

J Thorac Cardiovasc Surg 2018 06 8;155(6):2632-2633. Epub 2018 Feb 8.

Thoracic Epigenetics Section, Thoracic and Oncologic Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Md.

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http://dx.doi.org/10.1016/j.jtcvs.2018.01.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334846PMC
June 2018

Metabolomic and BH3 profiling of esophageal cancers: novel assessment methods for precision therapy.

BMC Gastroenterol 2018 Jun 22;18(1):94. Epub 2018 Jun 22.

Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, Building 10; 4-3952, 10 Center Drive, MSC 1201, Bethesda, MD, 20892-1201, USA.

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http://dx.doi.org/10.1186/s12876-018-0823-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6013848PMC
June 2018

CD38 knockout suppresses tumorigenesis in mice and clonogenic growth of human lung cancer cells.

Carcinogenesis 2018 02;39(2):242-251

Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL, USA.

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http://dx.doi.org/10.1093/carcin/bgx137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5862338PMC
February 2018

IKKα inactivation promotes Kras-initiated lung adenocarcinoma development through disrupting major redox regulatory pathways.

Proc Natl Acad Sci U S A 2018 01 8;115(4):E812-E821. Epub 2018 Jan 8.

Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, MD 21702;

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http://dx.doi.org/10.1073/pnas.1717520115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5789942PMC
January 2018

Circulating tumor DNA: Solid data from liquid biopsies.

Authors:
David S Schrump

J Thorac Cardiovasc Surg 2017 09 25;154(3):1132-1133. Epub 2017 May 25.

Thoracic Epigenetics Section, Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Md. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2017.05.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329385PMC
September 2017

Targeting the epigenome in malignant pleural mesothelioma.

Transl Lung Cancer Res 2017 Jun;6(3):350-365

Thoracic Epigenetics Section, Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.21037/tlcr.2017.06.06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5504118PMC
June 2017

Role of Local Ablative Therapy in Patients with Oligometastatic and Oligoprogressive Non-Small Cell Lung Cancer.

J Thorac Oncol 2017 02 22;12(2):179-193. Epub 2016 Oct 22.

Thoracic and Gastrointestinal Oncology Branch and Radiation Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.jtho.2016.10.012DOI Listing
February 2017

Whole-Cell Cancer Vaccines Induce Large Antibody Responses to Carbohydrates and Glycoproteins.

Cell Chem Biol 2016 Dec 23;23(12):1515-1525. Epub 2016 Nov 23.

Chemical Biology Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 376 Boyles Street, Room 208, Frederick, MD 21702, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2016.10.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5182097PMC
December 2016

Expression of mesothelin in thymic carcinoma and its potential therapeutic significance.

Lung Cancer 2016 11 28;101:104-110. Epub 2016 Sep 28.

Thoracic and Gastrointestinal Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.lungcan.2016.09.015DOI Listing
November 2016

Thoracic Surgery in Chronic Granulomatous Disease: a 25-Year Single-Institution Experience.

J Clin Immunol 2016 10 6;36(7):677-83. Epub 2016 Aug 6.

Thoracic and Gastrointestinal Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/s10875-016-0319-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329290PMC
October 2016

Rapidly Growing Chest Wall Mass in a Case of Sporadic Metastatic Paraganglioma: Imaging With 4 Different PET Radiopharmaceuticals.

Clin Nucl Med 2016 May;41(5):399-400

From the *Program in Adult and Reproductive Endocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, †Nuclear Medicine Division, Radiology and Imaging Sciences, Warren Grant Magnuson Clinical Center, and ‡Positron Emission Tomography Department, National Institutes of Health Clinical Center, National Institutes of Health; and §Center for Cancer Research, National Cancer Institute, Thoracic and Gastrointestinal Oncology Branch, Bethesda, MD.

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http://dx.doi.org/10.1097/RLU.0000000000001116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823168PMC
May 2016

Precision Therapy for Lung Cancer: Tyrosine Kinase Inhibitors and Beyond.

Semin Thorac Cardiovasc Surg 2015 8;27(1):36-48. Epub 2015 Apr 8.

Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland. Electronic address:

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http://dx.doi.org/10.1053/j.semtcvs.2015.04.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360071PMC
March 2016

Pulmonary Metastases Exhibit Epigenetic Clonality: Implications for Precision Cancer Therapy.

Ann Thorac Surg 2015 Nov 20;100(5):1839-48; discussion 1848. Epub 2015 Aug 20.

Thoracic Epigenetics Laboratory, Thoracic and GI Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2015.05.089DOI Listing
November 2015

Pulmonary mucosa-associated lymphoma in a patient with von Hippel-Lindau disease.

J Surg Case Rep 2015 Jul 14;2015(7). Epub 2015 Jul 14.

Department of Thoracic and GI Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/jscr/rjv080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500894PMC
July 2015

Ectopic adrenocorticotropic hormone and corticotropin-releasing hormone co-secreting tumors in children and adolescents causing cushing syndrome: a diagnostic dilemma and how to solve it.

J Clin Endocrinol Metab 2015 Jan;100(1):141-8

Section on Endocrinology and Genetics (A.S.K., J.B., M.F.K., C.L., M.B.L., C.A.S.), Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892; Section of Radiology and Imaging Sciences (G.Z.P., N.J.P.), Clinical Center, National Institutes of Health, Bethesda, Maryland 20892; Laboratory of Pathology (M.M.Q., M.M.), Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892; Thoracic and Gastrointestinal Oncology Branch (D.S.S.), Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892; Endocrine Oncology Branch (E.K.), Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892; Randall Children's Hospital at Legacy Emanuel (M.K.H.), Children's Diabetes and Endocrine Center, Portland, Oregon 97227; Department of Pediatrics (M.R.A., L.P.K., A.E.B.), Section of Diabetes and Endocrinology, Baylor College of Medicine, Houston, Texas 77030.

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http://dx.doi.org/10.1210/jc.2014-2945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4283025PMC
January 2015

Extended resections of non-small cell lung cancers invading the aorta, pulmonary artery, left atrium, or esophagus: can they be justified?

Thorac Surg Clin 2014 Nov 11;24(4):457-64. Epub 2014 Sep 11.

Thoracic Surgery Section, Thoracic and GI Oncology Branch, CCR/NCI, National Institutes of Health, Building 10, 4-3942, 10 Center Drive, MSC 1201, Bethesda, MD 20892-1201, USA. Electronic address:

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http://dx.doi.org/10.1016/j.thorsurg.2014.07.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301020PMC
November 2014

A systematic review and pooled analysis of CPR-associated cardiovascular and thoracic injuries.

Resuscitation 2014 Jun 10;85(6):724-31. Epub 2014 Feb 10.

Surgery Branch, Thoracic Oncology Section, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States.

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http://dx.doi.org/10.1016/j.resuscitation.2014.01.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4031922PMC
June 2014

Invited commentary.

Authors:
David S Schrump

Ann Thorac Surg 2014 Mar;97(3):1045

Thoracic and GI Oncology Branch, National Cancer Institute, Building 10; 4-3942, 10 Center Dr, Bethesda, MD 20892. Electronic address:

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http://dx.doi.org/10.1016/j.athoracsur.2013.12.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329458PMC
March 2014

A rapid ultra HPLC-MS/MS method for the quantitation and pharmacokinetic analysis of 3-deazaneplanocin A in mice.

J Chromatogr B Analyt Technol Biomed Life Sci 2013 May 9;927:142-6. Epub 2013 Jan 9.

Clinical Pharmacology Program, Office of the Clinical Director, National Cancer Institute, Bethesda, MD, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15700232130002
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http://dx.doi.org/10.1016/j.jchromb.2013.01.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640617PMC
May 2013

Cigarette smoke mediates epigenetic repression of miR-487b during pulmonary carcinogenesis.

J Clin Invest 2013 Mar 15;123(3):1241-61. Epub 2013 Feb 15.

Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1172/JCI61271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3582115PMC
March 2013

Aryl hydrocarbon receptor-induced adrenomedullin mediates cigarette smoke carcinogenicity in humans and mice.

Cancer Res 2012 Nov 19;72(22):5790-800. Epub 2012 Sep 19.

Angiogenesis Core Facility, Radiation Oncology Branch, Radiation Oncology Branch, Surgery Branch, National Cancer Institute, NIH, Bethesda, Maryland 21702-1201, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-12-0818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340077PMC
November 2012

Targeting epigenetic mediators of gene expression in thoracic malignancies.

Authors:
David S Schrump

Biochim Biophys Acta 2012 Jul 9;1819(7):836-45. Epub 2012 Apr 9.

Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, Rm. 4-3940, 10 Center Drive, MSC 1201, Bethesda, MD 20892-1201, USA.

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http://dx.doi.org/10.1016/j.bbagrm.2012.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310137PMC
July 2012

Operative management for recurrent and metastatic adrenocortical carcinoma.

J Surg Oncol 2012 Jun 20;105(7):709-13. Epub 2011 Dec 20.

Surgery Branch, National Cancer Institute/NIH, Building 10-Hatfield CRC Room 4-3961, 10 Center Drive, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1002/jso.23015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136651PMC
June 2012

Pulmonary resection for metastatic adrenocortical carcinoma: the National Cancer Institute experience.

Ann Thorac Surg 2011 Oct;92(4):1195-200

Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1016/j.athoracsur.2011.05.013DOI Listing
October 2011

ASPS-1, a novel cell line manifesting key features of alveolar soft part sarcoma.

J Pediatr Hematol Oncol 2011 Jul;33(5):360-8

Screening Technologies Branch, Developmental Therapeutics Program, National Cancer Institute at Frederick, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1097/MPH.0b013e3182002f9fDOI Listing
July 2011

Preoperative taxane-based chemotherapy and celecoxib for carcinoma of the esophagus and gastroesophageal junction: results of a phase 2 trial.

J Thorac Oncol 2011 Jun;6(6):1121-7

Thoracic Surgery Division, Department of Cardiothoracic Surgery, New York Presbyterian Hospital, Weill Cornell Medical College, New York City, New York 10021, USA.

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http://dx.doi.org/10.1097/JTO.0b013e31821529a9DOI Listing
June 2011

Thoracic metastasectomy for adoptive immunotherapy of melanoma: a single-institution experience.

J Thorac Cardiovasc Surg 2010 Dec 2;140(6):1276-82. Epub 2010 Jul 2.

Tumor Immunology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Md 20892, USA.

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http://dx.doi.org/10.1016/j.jtcvs.2010.05.020DOI Listing
December 2010

Pulmonary resection for metastatic gastric cancer.

J Thorac Oncol 2010 Nov;5(11):1796-805

Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892-1201, USA.

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http://dx.doi.org/10.1097/JTO.0b013e3181ed3514DOI Listing
November 2010

Cigarette smoke induces C/EBP-β-mediated activation of miR-31 in normal human respiratory epithelia and lung cancer cells.

PLoS One 2010 Oct 29;5(10):e13764. Epub 2010 Oct 29.

Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0013764PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2966442PMC
October 2010

Melanocytic bronchopulmonary carcinoid tumor in a patient with multiple endocrine neoplasia syndrome type 1: a case report with emphasis on intraoperative cytological findings.

Diagn Cytopathol 2010 Sep;38(9):669-74

Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

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http://dx.doi.org/10.1002/dc.21296DOI Listing
September 2010

Image of the month. Cystic parathyroid adenoma.

Arch Surg 2010 Jul;145(7):705

National Cancer Institute, Bethesda, Maryland, USA.

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http://dx.doi.org/10.1001/archsurg.2010.111-aDOI Listing
July 2010

A spectrum of severe familial liver disorders associate with telomerase mutations.

PLoS One 2009 Nov 20;4(11):e7926. Epub 2009 Nov 20.

Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007926PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775683PMC
November 2009

Cytotoxicity mediated by histone deacetylase inhibitors in cancer cells: mechanisms and potential clinical implications.

Authors:
David S Schrump

Clin Cancer Res 2009 Jun 9;15(12):3947-57. Epub 2009 Jun 9.

Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892-1201, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-2787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354580PMC
June 2009

Tobacco smoke induces polycomb-mediated repression of Dickkopf-1 in lung cancer cells.

Cancer Res 2009 Apr 7;69(8):3570-8. Epub 2009 Apr 7.

Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892-1201, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-2807DOI Listing
April 2009

Gene expression profiling of alveolar soft-part sarcoma (ASPS).

BMC Cancer 2009 Jan 15;9:22. Epub 2009 Jan 15.

Screening Technologies Branch, Developmental Therapeutics Program, National Cancer Institute at Frederick, Frederick, MD 21702, USA.

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http://dx.doi.org/10.1186/1471-2407-9-22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635365PMC
January 2009

Clinical and molecular responses in lung cancer patients receiving Romidepsin.

Clin Cancer Res 2008 Jan;14(1):188-98

Thoracic Oncology Section Surgery Branch, Center for Cancer Research and Cancer Therapy Evaluation Program, National Cancer Institute, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-0135DOI Listing
January 2008

The essential role of the mitochondria and reactive oxygen species in Cisplatin-mediated enhancement of fas ligand-induced apoptosis in malignant pleural mesothelioma.

J Surg Res 2007 Jul;141(1):120-31

Department of Surgery, Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

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http://dx.doi.org/10.1016/j.jss.2007.03.048DOI Listing
July 2007

Utilization of chromatin remodeling agents for lung cancer therapy.

Cancer J 2007 Jan-Feb;13(1):56-64

Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892-1201, USA.

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http://dx.doi.org/10.1097/PPO.0b013e31803c74cfDOI Listing
June 2007

The workup of stridor: virtual bronchoscopy as a complementary technique in the diagnosis of subglottic stenosis.

Respir Care 2007 Mar;52(3):337-9

Critiacl Care Medicine Department, National Institutes of Health Clinical Center, Bethesda, Maryland 20892-1662, USA.

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March 2007

Gossypol, a phytochemical with BH3-mimetic property, sensitizes cultured thoracic cancer cells to Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand.

J Thorac Cardiovasc Surg 2006 Dec 30;132(6):1356-62. Epub 2006 Oct 30.

Section of Thoracic Oncology, Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Md, USA.

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http://dx.doi.org/10.1016/j.jtcvs.2006.07.025DOI Listing
December 2006

Enhancement of Apo2L/TRAIL-mediated cytotoxicity in esophageal cancer cells by cisplatin.

Mol Cancer Ther 2006 Dec;5(12):2977-90

Section of Thoracic Oncology, Surgery Branch, Center for Cancer Research, National Cancer Institute, NIH, Room 4-4W-3940, 10 Center Drive, Bethesda, MD 20892-1502, USA.

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http://dx.doi.org/10.1158/1535-7163.MCT-05-0514DOI Listing
December 2006

Lung cancer staging in the genomics era.

Thorac Surg Clin 2006 Nov;16(4):329-37

Section of Thoracic Oncology, Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Room 4 W-4-3940, 10 Center Drive, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.thorsurg.2006.07.004DOI Listing
November 2006

Targeting the epigenome for the treatment of thoracic malignancies.

Thorac Surg Clin 2006 Nov;16(4):367-77, vi

Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, Room 4-3940, 10 Center Drive, MSC 1201, Bethesda, MD 20892-1201, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S15474127060005
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http://dx.doi.org/10.1016/j.thorsurg.2006.07.005DOI Listing
November 2006

Phase I study of decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura.

Clin Cancer Res 2006 Oct;12(19):5777-85

Thoracic Oncology Section Surgery Branch, Cancer Therapy Evaluation Program, National Cancer Institute/NIH, 10 Center Drive, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-0669DOI Listing
October 2006

Bortezomib and depsipeptide sensitize tumors to tumor necrosis factor-related apoptosis-inducing ligand: a novel method to potentiate natural killer cell tumor cytotoxicity.

Cancer Res 2006 Jul;66(14):7317-25

Hematology Branch, National Heart, Lung, and Blood Institute, Laboratory of Tumor Immunology and Biology, and Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, Maryland 20892-1202, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-0680DOI Listing
July 2006

Suppression of pro-metastasis phenotypes expression in malignant pleural mesothelioma by the PI3K inhibitor LY294002 or the MEK inhibitor UO126.

Anticancer Res 2006 Mar-Apr;26(2A):809-21

Section of Thoracic Oncology, Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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http://ar.iiarjournals.org/content/26/2A/809.full.pdf
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May 2006

Depletion of DNA methyltransferase 1 and/or DNA methyltransferase 3b mediates growth arrest and apoptosis in lung and esophageal cancer and malignant pleural mesothelioma cells.

J Thorac Cardiovasc Surg 2006 Feb 18;131(2):298-306. Epub 2006 Jan 18.

Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Md 20892, USA.

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http://dx.doi.org/10.1016/j.jtcvs.2005.05.022DOI Listing
February 2006

Novel molecular targeted therapy for esophageal cancer.

J Surg Oncol 2005 Dec;92(3):257-61

Thoracic Oncology Section, Surgery Branch, National Cancer Institute, Bldg. 10, Rm. 4-3490, 10 Center Drive MSC 1201, Bethesda, MD 20892, USA.

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http://doi.wiley.com/10.1002/jso.20367
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http://dx.doi.org/10.1002/jso.20367DOI Listing
December 2005

Targeting the epigenome for the treatment and prevention of lung cancer.

Semin Oncol 2005 Oct;32(5):488-502

Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD 20892-1201, USA.

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http://dx.doi.org/10.1053/j.seminoncol.2005.07.007DOI Listing
October 2005

The selective epidermal growth factor receptor tyrosine kinase inhibitor PD153035 suppresses expression of prometastasis phenotypes in malignant pleural mesothelioma cells in vitro.

J Thorac Cardiovasc Surg 2005 May;129(5):1010-7

Section of Thoracic Oncology, Surgery Branch, Center for Cancer Research, National Cancer Institute/NIH, 10 Center Drive, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.jtcvs.2004.10.040DOI Listing
May 2005

Sequential 5-Aza 2'-deoxycytidine/depsipeptide FK228 treatment induces tissue factor pathway inhibitor 2 (TFPI-2) expression in cancer cells.

Oncogene 2005 Mar;24(14):2386-97

Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1201, USA.

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http://dx.doi.org/10.1038/sj.onc.1208376DOI Listing
March 2005

Induction of apoptosis of lung and esophageal cancer cells treated with the combination of histone deacetylase inhibitor (trichostatin A) and protein kinase C inhibitor (calphostin C).

J Thorac Cardiovasc Surg 2005 Jan;129(1):53-63

Section of Thoracic Oncology, Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1502, USA.

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http://dx.doi.org/10.1016/j.jtcvs.2004.07.051DOI Listing
January 2005

Cisplatin enhances apoptosis induced by a tumor-selective adenovirus expressing tumor necrosis factor-related apoptosis-inducing ligand.

J Thorac Cardiovasc Surg 2004 Dec;128(6):883-91

Section of Thoracic Oncology, Surgery Branch, Center for Cancer Research, National Cancer Institute/NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.jtcvs.2004.06.036DOI Listing
December 2004

Growth factor receptors as targets for lung cancer therapy.

Semin Thorac Cardiovasc Surg 2004 ;16(1):3-12

Section of Thoracic Oncology, Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

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http://dx.doi.org/10.1053/j.semtcvs.2003.12.002DOI Listing
November 2004

Virtual bronchoscopy for evaluation of airway disease.

Thorac Surg Clin 2004 Feb;14(1):79-86

Thoracic Oncology Section, Surgery Branch, Center for Cancer Research, National Cancer Institute, Building 10, Room 2B-07, 10 Center Drive, National Institutes of Health, Bethesda, MD 20892-1502, USA.

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http://dx.doi.org/10.1016/S1547-4127(04)00037-4DOI Listing
February 2004