David S Knopman

David S Knopman

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David S Knopman

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Cognitive Reserve in Midlife is not Associated with Amyloid-β Deposition in Late-Life.

J Alzheimers Dis 2019 ;68(2):517-521

Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.3233/JAD-180785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6443418PMC
July 2020

The quest for dementia prevention does not include an aspirin a day.

Neurology 2020 Jul 25;95(3):105-106. Epub 2020 Mar 25.

From the Department of Neurology, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000009278DOI Listing
July 2020

Utility of FDG-PET in diagnosis of Alzheimer-related TDP-43 proteinopathy.

Neurology 2020 Jul 9;95(1):e23-e34. Epub 2020 Jun 9.

From the Departments of Neurology (M.B., H.B., D.T.J., D.S.K., B.F.B., R.C.P., K.A.J.), Radiology (C.G.S., M.L.S., C.R.J., V.L., J.L.W.), and Laboratory Medicine and Pathology (J.E.P.), Mayo Clinic, Rochester, MN; and Department of Neuroscience (M.E.M., L.P., D.W.D.), Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1212/WNL.0000000000009722DOI Listing
July 2020

Subtypes of dementia with Lewy bodies are associated with α-synuclein and tau distribution.

Neurology 2020 Jul 19;95(2):e155-e165. Epub 2020 Jun 19.

From the Departments of Psychiatry and Psychology (T.J.F., O.P.), Neurology (J.A.V.G., N.R.G.-R., R.J.U., Z.K.W.), and Neuroscience (M.E.M., O.A.R., D.W.D.) Mayo Clinic, Jacksonville, FL; Department of Psychiatry (N.A.), Yokohama University Medical Center, Japan; and Departments of Neurology (B.F.B., J.G.-R., D.S.K., R.C.P.), Health Sciences Research (J.A.A.), Radiology (K.K.), Laboratory Medicine and Pathology (J.E.P., R.R.R.), and Psychiatry and Psychology (J.A.F.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000009763DOI Listing
July 2020

Longitudinal structural and metabolic changes in frontotemporal dementia.

Neurology 2020 Jul 26;95(2):e140-e154. Epub 2020 Jun 26.

From the Memory and Aging Center, Department of Neurology (A.B., G.T., G.M., Y.C., L.I., J.K., A.M.S., M.G.-T., B.L.M., A.L.B., H.J.R., G.D.R.), and Department of Radiology and Biomedical Imaging (G.D.R.), University of California San Francisco; Frontotemporal Disorders Unit (B.C.D.), Department of Neurology, Massachusetts General Hospital, Boston; and Harvard Medical School, Charleston; Department of Neurology (B.F.B., D.S.K.), Mayo Clinic, Rochester, MN; Molecular Biophysics and Integrated Bioimaging Division (W.J.J., G.D.R.), Lawrence Berkeley National Laboratory, CA; and Helen Wills Neuroscience Institute (G.D.R.), University of California Berkeley.

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http://dx.doi.org/10.1212/WNL.0000000000009760DOI Listing
July 2020

CSF biomarkers in Olmsted County: Evidence of 2 subclasses and associations with demographics.

Neurology 2020 Jul 26;95(3):e256-e267. Epub 2020 Jun 26.

From the Departments of Neurology (A.C.V.H., M.M.M., D.S.K., R.C.P.), Health Sciences Research (H.J.W., S.D.W., M.M.M., W.K.K., R.C.P.), Laboratory Medicine and Pathology (R.B.D.), and Radiology (C.R.J.), Mayo Clinic, Rochester, MN; Department of Neurology and Alzheimer Center Amsterdam UMC (A.C.V.H.), the Netherlands; and Roche Diagnostics (U.E., R.B.-U., A.A.-S.), Basel, Switzerland.

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http://dx.doi.org/10.1212/WNL.0000000000009874DOI Listing
July 2020

The Enigma of Decreasing Dementia Incidence.

Authors:
David S Knopman

JAMA Netw Open 2020 Jul 1;3(7):e2011199. Epub 2020 Jul 1.

Department of Neurology, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1001/jamanetworkopen.2020.11199DOI Listing
July 2020

Medical Doctors and Dementia: A Longitudinal Study.

J Am Geriatr Soc 2020 Jun 22;68(6):1250-1255. Epub 2020 Feb 22.

Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.

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http://dx.doi.org/10.1111/jgs.16375DOI Listing
June 2020

Preoperative cognitive impairment associated with oversedation during recovery from anesthesia.

J Anesth 2020 Jun 28;34(3):390-396. Epub 2020 Mar 28.

Department of Anesthesiology and Perioperative Medicine (Drs. Kruthiventi, Laporta, Deljou, Sprung, and Weingarten), Department of Neurology (Drs. Knopman and Petersen), and Division of Biomedical Statistics and Informatics (Mr. Schroeder), Mayo Clinic, 200 First St SW, Rochester, MN, 55905, USA.

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http://dx.doi.org/10.1007/s00540-020-02764-0DOI Listing
June 2020

Association of Surgical Hospitalization with Brain Amyloid Deposition: The Atherosclerosis Risk in Communities-Positron Emission Tomography (ARIC-PET) Study.

Anesthesiology 2020 Jun;132(6):1407-1418

From the Departments of Neurology (K.A.W., R.F.G.) Radiology (D.F.W.) Anesthesiology (C.H.B.), Johns Hopkins School of Medicine, Baltimore, Maryland the Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (R.F.G., J.C., A.R.S.) the Department of Neurology, Mayo Clinic, Rochester, Minnesota (D.S.K.) Department of Medicine, Division of Geriatrics, University of Mississippi Medical Center, Jackson, Mississippi (T.H.M.) the Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia (A.A.) the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri (Y.Z.).

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http://dx.doi.org/10.1097/ALN.0000000000003255DOI Listing
June 2020

An agnostic reevaluation of the amyloid cascade hypothesis of Alzheimer's disease pathogenesis: The role of APP homeostasis.

Alzheimers Dement 2020 Jun 26. Epub 2020 Jun 26.

Department of Neuroscience, Mayo Clinic Florida, Jacksonville, Florida, USA.

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http://dx.doi.org/10.1002/alz.12124DOI Listing
June 2020

Albuminuria and Estimated GFR as Risk Factors for Dementia in Midlife and Older Age: Findings From the ARIC Study.

Am J Kidney Dis 2020 May 16. Epub 2020 May 16.

Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD; Stanley Steyer School of Health Professions, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address:

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http://dx.doi.org/10.1053/j.ajkd.2020.03.015DOI Listing
May 2020

Better stress coping associated with lower tau in amyloid-positive cognitively unimpaired older adults.

Neurology 2020 04 21;94(15):e1571-e1579. Epub 2020 Jan 21.

From the Departments of Radiology (E.M.A.-U., V.J.L., A.L.R., C.R.J., P.V.), Health Sciences Research (S.A.P., M.M.M.), Psychiatry and Psychology (M.M. Machulda), and Neurology (D.S.K., M.M. Mielke, R.C.P.), Mayo Clinic, Rochester, MN; and Department of Neurology (Y.E.G.), Mayo Clinic, Scottsdale, AZ.

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http://dx.doi.org/10.1212/WNL.0000000000008979DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251516PMC
April 2020

Witnessed apneas are associated with elevated tau-PET levels in cognitively unimpaired elderly.

Neurology 2020 Apr 26;94(17):e1793-e1802. Epub 2020 Mar 26.

From the Departments of Neurology (D.Z.C., E.K.S.L., B.F.B., M.M.M., D.S.K., R.C.P.), Radiology (C.G.S., V.J.L., A.R., C.R.J., P.V.), and Health Sciences Research (S.A.P., M.M.M.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000009315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7274847PMC
April 2020

Exposure to surgery with regional anesthesia and cortical thickness in older adults.

Alzheimers Dement (N Y) 2020 7;6(1):e12012. Epub 2020 Apr 7.

Department of Anesthesiology Mayo Clinic College of Medicine and Science Rochester Minnesota USA.

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http://dx.doi.org/10.1002/trc2.12012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7139122PMC
April 2020

Linear vs volume measures of ventricle size: Relation to present and future gait and cognition.

Neurology 2020 02 20;94(5):e549-e556. Epub 2019 Nov 20.

From the Departments of Health Sciences Research (J.E.C., C.T.B.) and Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL; and Departments of Radiology (J.L.G., C.R.J.) and Neurology (D.T.J., J.G.-R., D.S.K., B.F.B., R.C.P.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000008673DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7080290PMC
February 2020

Age at symptom onset and death and disease duration in genetic frontotemporal dementia: an international retrospective cohort study.

Authors:
Katrina M Moore Jennifer Nicholas Murray Grossman Corey T McMillan David J Irwin Lauren Massimo Vivianna M Van Deerlin Jason D Warren Nick C Fox Martin N Rossor Simon Mead Martina Bocchetta Bradley F Boeve David S Knopman Neill R Graff-Radford Leah K Forsberg Rosa Rademakers Zbigniew K Wszolek John C van Swieten Lize C Jiskoot Lieke H Meeter Elise Gp Dopper Janne M Papma Julie S Snowden Jennifer Saxon Matthew Jones Stuart Pickering-Brown Isabelle Le Ber Agnès Camuzat Alexis Brice Paola Caroppo Roberta Ghidoni Michela Pievani Luisa Benussi Giuliano Binetti Bradford C Dickerson Diane Lucente Samantha Krivensky Caroline Graff Linn Öijerstedt Marie Fallström Håkan Thonberg Nupur Ghoshal John C Morris Barbara Borroni Alberto Benussi Alessandro Padovani Daniela Galimberti Elio Scarpini Giorgio G Fumagalli Ian R Mackenzie Ging-Yuek R Hsiung Pheth Sengdy Adam L Boxer Howie Rosen Joanne B Taylor Matthis Synofzik Carlo Wilke Patricia Sulzer John R Hodges Glenda Halliday John Kwok Raquel Sanchez-Valle Albert Lladó Sergi Borrego-Ecija Isabel Santana Maria Rosário Almeida Miguel Tábuas-Pereira Fermin Moreno Myriam Barandiaran Begoña Indakoetxea Johannes Levin Adrian Danek James B Rowe Thomas E Cope Markus Otto Sarah Anderl-Straub Alexandre de Mendonça Carolina Maruta Mario Masellis Sandra E Black Philippe Couratier Geraldine Lautrette Edward D Huey Sandro Sorbi Benedetta Nacmias Robert Laforce Marie-Pier L Tremblay Rik Vandenberghe Philip Van Damme Emily J Rogalski Sandra Weintraub Alexander Gerhard Chiadi U Onyike Simon Ducharme Sokratis G Papageorgiou Adeline Su Lyn Ng Amy Brodtmann Elizabeth Finger Rita Guerreiro Jose Bras Jonathan D Rohrer

Lancet Neurol 2020 02 3;19(2):145-156. Epub 2019 Dec 3.

Dementia Research Centre, Department of Neurodegenerative Disease, Institute of Neurology, University College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/S1474-4422(19)30394-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7007771PMC
February 2020

Chronic Systemic Inflammation Is Associated With Symptoms of Late-Life Depression: The ARIC Study.

Am J Geriatr Psychiatry 2020 01 21;28(1):87-98. Epub 2019 May 21.

Department of Neurology (KAW), Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address:

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http://dx.doi.org/10.1016/j.jagp.2019.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868307PMC
January 2020

Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration.

Alzheimers Dement 2020 01 6;16(1):37-48. Epub 2020 Jan 6.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco CA, USA University of California, San Francisco, San Francisco CA, USA.

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http://dx.doi.org/10.1016/j.jalz.2019.04.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938544PMC
January 2020

Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration.

Alzheimers Dement 2020 01 6;16(1):49-59. Epub 2020 Jan 6.

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.jalz.2019.08.196DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988137PMC
January 2020

Cerebral microbleed incidence, relationship to amyloid burden: The Mayo Clinic Study of Aging.

Neurology 2020 01 4;94(2):e190-e199. Epub 2019 Dec 4.

From the Departments of Neurology (J.G.-R., A.A.R., R.D.B., M.M.M., D.S.K., R.C.P.), Health Sciences Research (T.L., J.G., J.A., S.A.P., M.M.M., W.K.), and Radiology (A.J.S., J.H., V.J.L., C.R.J., P.V., K.K.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000008735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6988987PMC
January 2020

β-Amyloid PET and neuropathology in dementia with Lewy bodies.

Neurology 2020 01 20;94(3):e282-e291. Epub 2019 Dec 20.

From the Departments of Radiology (K.K., V.J.L., Q.C., C.G.S., C.R.J.), Health Sciences Research (S.A.P., T.G.L.), Information Technology (M.L.S., J.L.G.), Neurology (J.G.-R., D.T.J., D.S.K., R.C.P., B.F.B.), and Laboratory Medicine and Pathology (J.E.P.), Mayo Clinic, Rochester, MN; Department of Neurology (Q.C.), West China Hospital, Chengdu, Sichuan; and Departments of Neurology (N.G.-R.), Psychiatry and Psychology (T.J.F.), and Laboratory Medicine and Pathology (D.W.D., M.E.M.), Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1212/WNL.0000000000008818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7108811PMC
January 2020

Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint.

Alzheimers Dement 2020 01;16(1):11-21

Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/j.jalz.2019.01.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842665PMC
January 2020

Associations Between Left Ventricular Structure, Function, and Cerebral Amyloid: The ARIC-PET Study.

Stroke 2019 12 10;50(12):3622-3624. Epub 2019 Oct 10.

From the The Johns Hopkins University School of Medicine, Baltimore, MD (M.C.J., D.F.W., R.F.G.).

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http://dx.doi.org/10.1161/STROKEAHA.119.027220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6878182PMC
December 2019

Cerebrospinal fluid dynamics disorders: Relationship to Alzheimer biomarkers and cognition.

Neurology 2019 12 12;93(24):e2237-e2246. Epub 2019 Nov 12.

From the Departments of Neurology (J.G.-R., D.T.J., R.C.P., D.S.K.), Radiology (J.L.G., C.G.S., J.H., V.L., N.B.G., K.K., P.V., C.R.J.), Health Sciences Research (S.A.P., M.M. Mielke), Neurologic Surgery (B.D.E.), and Psychiatry and Psychology (M.M. Machulda), Mayo Clinic, Rochester, MN; and Department of Neurology (N.R.G.-R.), Mayo Clinic, Jacksonville, FL.

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http://dx.doi.org/10.1212/WNL.0000000000008616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937493PMC
December 2019

High-Sensitive Troponin T, Natriuretic Peptide, and Cognitive Change.

J Am Geriatr Soc 2019 11 30;67(11):2353-2361. Epub 2019 Jul 30.

Department of Epidemiology and Biostatistics, Milken Institute School of Public Health, The George Washington University, Washington, District of Columbia.

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http://dx.doi.org/10.1111/jgs.16092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6861618PMC
November 2019

Association of white matter microstructural integrity with cognition and dementia.

Neurobiol Aging 2019 11 29;83:63-72. Epub 2019 Aug 29.

Department of Neurology, University of Mississippi Medical Center, Jackson, MS, USA; Department of Geriatrics, University of Mississippi Medical Center, Jackson, MS, USA.

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http://dx.doi.org/10.1016/j.neurobiolaging.2019.08.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6914220PMC
November 2019

Comparison of variables associated with cerebrospinal fluid neurofilament, total-tau, and neurogranin.

Alzheimers Dement 2019 11 23;15(11):1437-1447. Epub 2019 Oct 23.

Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USA; Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Mölndal, Sweden.

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http://dx.doi.org/10.1016/j.jalz.2019.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6874755PMC
November 2019

Quantity and quality of mental activities and the risk of incident mild cognitive impairment.

Neurology 2019 08 10;93(6):e548-e558. Epub 2019 Jul 10.

From Translational Neuroscience and Aging Laboratory (J.K.-R., Y.E.G.) and Departments of Psychiatry and Psychology (Y.E.G.) and Neurology (Y.E.G.), Mayo Clinic, Scottsdale, AZ; Departments of Health Sciences Research (J.A.S., M.V., M.M. Mielke, W.K.K., Y.E.G.), Psychiatry and Psychology (M.M. Machulda), and Neurology (M.M. Mielke, D.S.K., R.C.P.), Mayo Clinic, Rochester, MN; and Institute of Sports and Sports Science (J.K.-R.), Karlsruhe Institute of Technology, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000007897DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6710000PMC
August 2019

Neuropsychological subtypes of incident mild cognitive impairment in the Mayo Clinic Study of Aging.

Alzheimers Dement 2019 07 23;15(7):878-887. Epub 2019 May 23.

Department of Neurology, College of Medicine and Science, Mayo Clinic, Rochester, MN, USA.

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http://dx.doi.org/10.1016/j.jalz.2019.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6646057PMC
July 2019

Cross-sectional associations of tau-PET signal with cognition in cognitively unimpaired adults.

Neurology 2019 07 30;93(1):e29-e39. Epub 2019 May 30.

From the Departments of Radiology (V.J.L., T.J.B., H.-K.M., P.F., M.L.S., M.K.P., K.K., D.T.J., P.V., C.G.S., C.R.J.), Health Sciences Research (H.J.W., S.D.W., T.M.T., M.M. Mielke, R.O.R.), Information Technology (M.L.S.), Neurology (B.F.B., K.A.J., D.T.J., J.G.-R., M.M. Mielke, D.S.K., R.C.P.), Neuroscience (M.E.M.), and Psychiatry and Psychology (M.M. Machulda), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000007728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6659005PMC
July 2019

Plasma and CSF neurofilament light: Relation to longitudinal neuroimaging and cognitive measures.

Neurology 2019 07 10;93(3):e252-e260. Epub 2019 Jun 10.

From the Departments of Health Sciences Research (M.M. Mielke, J.A.S., W.K.K., R.C.P., S.K.), Neurology (M.M. Mielke, D.S.K., R.C.P.), Radiology (P.V., C.J.), and Psychiatry and Psychology (M.M. Machulda), Mayo Clinic, Rochester, MN; Department of Psychiatry and Neurochemistry (K.B., H.Z., I.S., S.K.), Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg; Clinical Neurochemistry Laboratory (K.B., H.Z.), Sahlgrenska University Hospital, Mölndal, Sweden; Institute of Neurology (H.Z.), University College London, Queen Square; and UK Dementia Research Institute at UCL (H.Z.), London, UK.

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http://dx.doi.org/10.1212/WNL.0000000000007767DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6656645PMC
July 2019

Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.

Authors:
Cyril Pottier Yingxue Ren Ralph B Perkerson Matt Baker Gregory D Jenkins Marka van Blitterswijk Mariely DeJesus-Hernandez Jeroen G J van Rooij Melissa E Murray Elizabeth Christopher Shannon K McDonnell Zachary Fogarty Anthony Batzler Shulan Tian Cristina T Vicente Billie Matchett Anna M Karydas Ging-Yuek Robin Hsiung Harro Seelaar Merel O Mol Elizabeth C Finger Caroline Graff Linn Öijerstedt Manuela Neumann Peter Heutink Matthis Synofzik Carlo Wilke Johannes Prudlo Patrizia Rizzu Javier Simon-Sanchez Dieter Edbauer Sigrun Roeber Janine Diehl-Schmid Bret M Evers Andrew King M Marsel Mesulam Sandra Weintraub Changiz Geula Kevin F Bieniek Leonard Petrucelli Geoffrey L Ahern Eric M Reiman Bryan K Woodruff Richard J Caselli Edward D Huey Martin R Farlow Jordan Grafman Simon Mead Lea T Grinberg Salvatore Spina Murray Grossman David J Irwin Edward B Lee EunRan Suh Julie Snowden David Mann Nilufer Ertekin-Taner Ryan J Uitti Zbigniew K Wszolek Keith A Josephs Joseph E Parisi David S Knopman Ronald C Petersen John R Hodges Olivier Piguet Ethan G Geier Jennifer S Yokoyama Robert A Rissman Ekaterina Rogaeva Julia Keith Lorne Zinman Maria Carmela Tartaglia Nigel J Cairns Carlos Cruchaga Bernardino Ghetti Julia Kofler Oscar L Lopez Thomas G Beach Thomas Arzberger Jochen Herms Lawrence S Honig Jean Paul Vonsattel Glenda M Halliday John B Kwok Charles L White Marla Gearing Jonathan Glass Sara Rollinson Stuart Pickering-Brown Jonathan D Rohrer John Q Trojanowski Vivianna Van Deerlin Eileen H Bigio Claire Troakes Safa Al-Sarraj Yan Asmann Bruce L Miller Neill R Graff-Radford Bradley F Boeve William W Seeley Ian R A Mackenzie John C van Swieten Dennis W Dickson Joanna M Biernacka Rosa Rademakers

Acta Neuropathol 2019 06 9;137(6):879-899. Epub 2019 Feb 9.

Department of Neuroscience, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.

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http://link.springer.com/10.1007/s00401-019-01962-9
Publisher Site
http://dx.doi.org/10.1007/s00401-019-01962-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533145PMC
June 2019

A brief history of "Alzheimer disease": Multiple meanings separated by a common name.

Neurology 2019 05 26;92(22):1053-1059. Epub 2019 Apr 26.

From the Departments of Neurology (D.S.K., R.C.P.) and Radiology (C.R.J.), Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1212/WNL.0000000000007583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6556090PMC
May 2019

Author Correction: Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.

Authors:
Gail Davies Max Lam Sarah E Harris Joey W Trampush Michelle Luciano W David Hill Saskia P Hagenaars Stuart J Ritchie Riccardo E Marioni Chloe Fawns-Ritchie David C M Liewald Judith A Okely Ari V Ahola-Olli Catriona L K Barnes Lars Bertram Joshua C Bis Katherine E Burdick Andrea Christoforou Pamela DeRosse Srdjan Djurovic Thomas Espeseth Stella Giakoumaki Sudheer Giddaluru Daniel E Gustavson Caroline Hayward Edith Hofer M Arfan Ikram Robert Karlsson Emma Knowles Jari Lahti Markus Leber Shuo Li Karen A Mather Ingrid Melle Derek Morris Christopher Oldmeadow Teemu Palviainen Antony Payton Raha Pazoki Katja Petrovic Chandra A Reynolds Muralidharan Sargurupremraj Markus Scholz Jennifer A Smith Albert V Smith Natalie Terzikhan Anbupalam Thalamuthu Stella Trompet Sven J van der Lee Erin B Ware B Gwen Windham Margaret J Wright Jingyun Yang Jin Yu David Ames Najaf Amin Philippe Amouyel Ole A Andreassen Nicola J Armstrong Amelia A Assareh John R Attia Deborah Attix Dimitrios Avramopoulos David A Bennett Anne C Böhmer Patricia A Boyle Henry Brodaty Harry Campbell Tyrone D Cannon Elizabeth T Cirulli Eliza Congdon Emily Drabant Conley Janie Corley Simon R Cox Anders M Dale Abbas Dehghan Danielle Dick Dwight Dickinson Johan G Eriksson Evangelos Evangelou Jessica D Faul Ian Ford Nelson A Freimer He Gao Ina Giegling Nathan A Gillespie Scott D Gordon Rebecca F Gottesman Michael E Griswold Vilmundur Gudnason Tamara B Harris Annette M Hartmann Alex Hatzimanolis Gerardo Heiss Elizabeth G Holliday Peter K Joshi Mika Kähönen Sharon L R Kardia Ida Karlsson Luca Kleineidam David S Knopman Nicole A Kochan Bettina Konte John B Kwok Stephanie Le Hellard Teresa Lee Terho Lehtimäki Shu-Chen Li Christina M Lill Tian Liu Marisa Koini Edythe London Will T Longstreth Oscar L Lopez Anu Loukola Tobias Luck Astri J Lundervold Anders Lundquist Leo-Pekka Lyytikäinen Nicholas G Martin Grant W Montgomery Alison D Murray Anna C Need Raymond Noordam Lars Nyberg William Ollier Goran Papenberg Alison Pattie Ozren Polasek Russell A Poldrack Bruce M Psaty Simone Reppermund Steffi G Riedel-Heller Richard J Rose Jerome I Rotter Panos Roussos Suvi P Rovio Yasaman Saba Fred W Sabb Perminder S Sachdev Claudia L Satizabal Matthias Schmid Rodney J Scott Matthew A Scult Jeannette Simino P Eline Slagboom Nikolaos Smyrnis Aïcha Soumaré Nikos C Stefanis David J Stott Richard E Straub Kjetil Sundet Adele M Taylor Kent D Taylor Ioanna Tzoulaki Christophe Tzourio André Uitterlinden Veronique Vitart Aristotle N Voineskos Jaakko Kaprio Michael Wagner Holger Wagner Leonie Weinhold K Hoyan Wen Elisabeth Widen Qiong Yang Wei Zhao Hieab H H Adams Dan E Arking Robert M Bilder Panos Bitsios Eric Boerwinkle Ornit Chiba-Falek Aiden Corvin Philip L De Jager Stéphanie Debette Gary Donohoe Paul Elliott Annette L Fitzpatrick Michael Gill David C Glahn Sara Hägg Narelle K Hansell Ahmad R Hariri M Kamran Ikram J Wouter Jukema Eero Vuoksimaa Matthew C Keller William S Kremen Lenore Launer Ulman Lindenberger Aarno Palotie Nancy L Pedersen Neil Pendleton David J Porteous Katri Räikkönen Olli T Raitakari Alfredo Ramirez Ivar Reinvang Igor Rudan Dan Rujescu Reinhold Schmidt Helena Schmidt Peter W Schofield Peter R Schofield John M Starr Vidar M Steen Julian N Trollor Steven T Turner Cornelia M Van Duijn Arno Villringer Daniel R Weinberger David R Weir James F Wilson Anil Malhotra Andrew M McIntosh Catharine R Gale Sudha Seshadri Thomas H Mosley Jan Bressler Todd Lencz Ian J Deary

Nat Commun 2019 May 1;10(1):2068. Epub 2019 May 1.

Centre for Cognitive Ageing and Cognitive Epidemiology, Department of Psychology, School of Philosophy, Psychology and Language Sciences, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.

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http://dx.doi.org/10.1038/s41467-019-10160-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6494826PMC
May 2019

Lowering of Amyloid-Beta by β-Secretase Inhibitors - Some Informative Failures.

Authors:
David S Knopman

N Engl J Med 2019 04;380(15):1476-1478

From the Department of Neurology, Mayo Clinic, Rochester, MN.

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http://dx.doi.org/10.1056/NEJMe1903193DOI Listing
April 2019

Neural correlates of domain-specific cognitive decline: The ARIC-NCS Study.

Neurology 2019 03 6;92(10):e1051-e1063. Epub 2019 Feb 6.

From the Department of Neurology (A.L.C.S., R.F.G.), Johns Hopkins University School of Medicine, Baltimore, MD; Departments of Radiology (M.L.S., J.L.G., C.G.S. C.R.J.), Information Technology (M.L.S., J.L.G.), and Neurology (D.S.K.), Mayo Clinic, Rochester, MN; Department of Epidemiology (A.W., A.G., R.F.G., A.R.S.), Johns Hopkins University Bloomberg School of Public Health; Johns Hopkins University Center on Aging and Health (A.G.), Baltimore, MD; and Department of Geriatrics (T.H.M.), University of Mississippi Medical Center, Jackson.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000007042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442014PMC
March 2019

Systemic inflammation during midlife and cognitive change over 20 years: The ARIC Study.

Neurology 2019 03 13;92(11):e1256-e1267. Epub 2019 Feb 13.

From the Departments of Neurology (K.A.W., R.F.G.) and Epidemiology (R.F.G., A.W., A.L.G., E.S.), Johns Hopkins University, Baltimore, MD; Department of Neurology (D.S.K.), Mayo Clinic, Rochester, MN; Department of Medicine (T.H.M., B.G.W.), Division of Geriatrics, University of Mississippi Medical Center, Jackson.

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http://dx.doi.org/10.1212/WNL.0000000000007094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6511107PMC
March 2019

Neuroimaging findings in midlife and risk of late-life dementia over 20 years of follow-up.

Neurology 2019 02 18;92(9):e917-e923. Epub 2019 Jan 18.

From the Department of Preventive Medicine (N.A.W.) and Department of Medicine (B.G.W., T.H.M.), Division of Geriatrics, University of Mississippi Medical Center, Jackson; Department of Neurology (D.S.K.), Mayo Clinic, Rochester, MN; Department of Radiology (D.K.S.), University of Washington Medical Center, Seattle; and Division of Public Health Sciences (L.H.C.), Wake Forest School of Medicine, Winston-Salem, NC.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6404467PMC
February 2019