David S Block

David S Block

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David S Block

David S Block

Publications by authors named "David S Block"

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Recombinant human IgG1 based Fc multimers, with limited FcR binding capacity, can effectively inhibit complement-mediated disease.

J Autoimmun 2017 Nov 19;84:97-108. Epub 2017 Aug 19.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, 16 S. Eutaw Street, Baltimore, MD, 21201, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08968411173036
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http://dx.doi.org/10.1016/j.jaut.2017.08.004DOI Listing
November 2017

A fully recombinant human IgG1 Fc multimer (GL-2045) inhibits complement-mediated cytotoxicity and induces iC3b.

Blood Adv 2017 Mar 14;1(8):504-515. Epub 2017 Mar 14.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1182/bloodadvances.2016001917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728453PMC
March 2017

Anti-CD20 Antibody with Multimerized Fc Domains: A Novel Strategy To Deplete B Cells and Augment Treatment of Autoimmune Disease.

J Immunol 2016 Feb 22;196(3):1165-76. Epub 2015 Dec 22.

Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, MD, 21201;

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http://dx.doi.org/10.4049/jimmunol.1501755DOI Listing
February 2016

Tumour antigen targeted monoclonal antibodies incorporating a novel multimerisation domain significantly enhance antibody dependent cellular cytotoxicity against colon cancer.

Eur J Cancer 2013 Oct 18;49(15):3344-52. Epub 2013 Jul 18.

Baltimore Veterans Administration Medical Center, Section of Surgical Oncology, and Research and Development Service, 10 N. Greene Street, 5C Surgical Services Area, Baltimore, MD 21201, USA; Division of General and Oncologic Surgery, University of Maryland School of Medicine, 22 S. Greene Street, Room S4B12, Baltimore, MD 21201, USA; Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, 16 S. Eutaw Street, Baltimore, MD 21201, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2013.06.009DOI Listing
October 2013

Ecdysteroid concentrations through various life-stages of the meiobenthic harpacticoid copepod, Amphiascus tenuiremis and the benthic estuarine amphipod, Leptocheirus plumulosus.

Gen Comp Endocrinol 2003 Jun;132(1):151-60

Department of Environmental Health Sciences, University of South Carolina, 800 Sumter Street, Room 311, Columbia, SC 29208, USA.

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http://dx.doi.org/10.1016/s0016-6480(03)00062-5DOI Listing
June 2003

Endocrine-mediated effects of UV-A irradiation on grass shrimp (Palaemonetes pugio) reproduction.

Comp Biochem Physiol C Toxicol Pharmacol 2002 Nov;133(3):419-34

Department of Environmental Health Sciences, University of South Carolina, Columbia, SC 29208, USA.

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http://dx.doi.org/10.1016/s1532-0456(02)00145-xDOI Listing
November 2002