David Ruau

David Ruau

UNVERIFIED PROFILE

Are you David Ruau?   Register this Author

Register author
David Ruau

David Ruau

Publications by authors named "David Ruau"

Are you David Ruau?   Register this Author

28Publications

466Reads

25Profile Views

Data Science Solution to Event Prediction in Outsourced Clinical Trial Models.

Stud Health Technol Inform 2015 ;216:1065

Advanced Analytics Centre, Biometrics and Information Sciences, AstraZeneca, Sweden/UK.

View Article

Download full-text PDF

Source
December 2016

CODEX: a next-generation sequencing experiment database for the haematopoietic and embryonic stem cell communities.

Nucleic Acids Res 2015 Jan 30;43(Database issue):D1117-23. Epub 2014 Sep 30.

Department of Haematology, Wellcome Trust-MRC Cambridge Stem Cell Institute & Cambridge Institute for Medical Research, Cambridge University, Cambridge CB2 0XY, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gku895DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384009PMC
January 2015

Constrained transcription factor spacing is prevalent and important for transcriptional control of mouse blood cells.

Nucleic Acids Res 2014 Dec 26;42(22):13513-24. Epub 2014 Nov 26.

Department of Haematology, Wellcome Trust and MRC Cambridge Stem Cell Institute & Cambridge Institute for Medical Research, Cambridge University, Cambridge CB2 0XY, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gku1254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267662PMC
December 2014

TRES predicts transcription control in embryonic stem cells.

Bioinformatics 2014 Oct 23;30(20):2983-5. Epub 2014 Jun 23.

The Roslin Institute and Royal (Dick) School of Veterinary Studies, Division of Developmental Biology, University of Edinburgh, Easter Bush Campus, Midlothian, EH25 8GR, UK and Department of Haematology, Wellcome Trust and MRC Cambridge Stem Cell Institute, Cambridge Institute for Medical Research, Cambridge University, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btu399DOI Listing
October 2014

Disease risk factors identified through shared genetic architecture and electronic medical records.

Sci Transl Med 2014 Apr;6(234):234ra57

Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, 1265 Welch Road, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scitranslmed.3007191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323098PMC
April 2014

Systematic identification of risk factors for Alzheimer's disease through shared genetic architecture and electronic medical records.

Pac Symp Biocomput 2013 :224-35

Div. of Systems Medicine, Dept. of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
December 2013

Building an ENCODE-style data compendium on a shoestring.

Nat Methods 2013 Oct;10(10):926

1] Department of Hematology, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK. [2] Wellcome Trust-Medical Research Council (MRC) Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nmeth.2643DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167595PMC
October 2013

Systematic identification of DNA variants associated with ultraviolet radiation using a novel Geographic-Wide Association Study (GeoWAS).

BMC Med Genet 2013 Jun 20;14:62. Epub 2013 Jun 20.

Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, 1265 Welch Road, MS-5415, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2350-14-62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699381PMC
June 2013

Integrative approach to pain genetics identifies pain sensitivity loci across diseases.

PLoS Comput Biol 2012 7;8(6):e1002538. Epub 2012 Jun 7.

Department of Anesthesia, Stanford University School of Medicine, Stanford, California, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pcbi.1002538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3369906PMC
October 2012

Type 2 diabetes risk alleles demonstrate extreme directional differentiation among human populations, compared to other diseases.

PLoS Genet 2012 12;8(4):e1002621. Epub 2012 Apr 12.

Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, California, United States of America.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pgen.1002621DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3325177PMC
September 2012

Quantifying multi-ethnic representation in genetic studies of high mortality diseases.

AMIA Jt Summits Transl Sci Proc 2012 19;2012:11-8. Epub 2012 Mar 19.

Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3392055PMC
August 2012

Sex differences in reported pain across 11,000 patients captured in electronic medical records.

J Pain 2012 Mar 13;13(3):228-34. Epub 2012 Jan 13.

Division of Systems Medicine, Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S152659001100872
Publisher Site
http://dx.doi.org/10.1016/j.jpain.2011.11.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3293998PMC
March 2012

Comparison of automated and human assignment of MeSH terms on publicly-available molecular datasets.

J Biomed Inform 2011 Dec 21;44 Suppl 1:S39-43. Epub 2011 Mar 21.

Division of Systems Medicine, Department of Pediatrics, Stanford, CA 94305, USA.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S153204641100058
Publisher Site
http://dx.doi.org/10.1016/j.jbi.2011.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3155012PMC
December 2011

Neural induction intermediates exhibit distinct roles of Fgf signaling.

Stem Cells 2010 Oct;28(10):1772-81

Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Münster, North Rhine-Westphalia, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/stem.498DOI Listing
October 2010

Gold nanoparticles of diameter 1.4 nm trigger necrosis by oxidative stress and mitochondrial damage.

Small 2009 Sep;5(18):2067-76

Biomedical Engineering, Biointerface Laboratory, RWTH Aachen University, Aachen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/smll.200900466DOI Listing
September 2009

GAR22: a novel target gene of thyroid hormone receptor causes growth inhibition in human erythroid cells.

Exp Hematol 2009 May;37(5):539-548.e4

Institute for Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Medical School, Aachen, Germany.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S0301472X0900050
Publisher Site
http://dx.doi.org/10.1016/j.exphem.2009.02.002DOI Listing
May 2009

The transcription factor repertoire of Flt3+ hematopoietic stem cells.

Cells Tissues Organs 2008 4;188(1-2):103-15. Epub 2008 Jan 4.

Institute for Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Medical School, Aachen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1159/000112836DOI Listing
September 2008

Pluripotent stem cells induced from adult neural stem cells by reprogramming with two factors.

Nature 2008 Jul 29;454(7204):646-50. Epub 2008 Jun 29.

Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, Röntgenstrasse 20, 48149 Münster, NRW, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature07061DOI Listing
July 2008

Pluripotency associated genes are reactivated by chromatin-modifying agents in neurosphere cells.

Stem Cells 2008 Apr 17;26(4):920-6. Epub 2008 Jan 17.

Institute for Biomedical Engineering, Department of Cell Biology, Rheinisch-Westfälische Technische Hochscule Aachen University, Aachen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1634/stemcells.2007-0649DOI Listing
April 2008

Transforming growth factor beta1 up-regulates interferon regulatory factor 8 during dendritic cell development.

Eur J Immunol 2007 May;37(5):1174-83

Institute for Biomedical Engineering, Department of Cell Biology, Aachen University Hospital, Aachen, Germany.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/eji.200636504
Publisher Site
http://dx.doi.org/10.1002/eji.200636504DOI Listing
May 2007

Genomics of TGF-beta1 signaling in stem cell commitment and dendritic cell development.

Cell Immunol 2006 Dec 16;244(2):116-20. Epub 2007 Apr 16.

Institute for Biomedical Engineering, Department of Cell Biology, Aachen University Medical School, Pauwelsstrasse 30, 52074 Aachen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cellimm.2007.01.011DOI Listing
December 2006

Update of NUREBASE: nuclear hormone receptor functional genomics.

Nucleic Acids Res 2004 Jan;32(Database issue):D165-7

Laboratoire de Biologie Moléculaire de la Cellule, CNRS UMR 5161, Ecole Normale Supérieure de Lyon, 46 allée d'Italie, 69364 Lyon Cedex 07, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkh062DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC308796PMC
January 2004