David R Van Wagoner

David R Van Wagoner

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David R Van Wagoner

Publications by authors named "David R Van Wagoner"

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Plasma endothelin-1 levels are increased in atrial fibrillation patients with hyperthyroidism.

PLoS One 2018 4;13(12):e0208206. Epub 2018 Dec 4.

Department of Molecular Cardiology, Cleveland Clinic, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208206PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6279224PMC
May 2019

Editorial commentary: A CRISPR approach to the study and treatment of cardiovascular disease.

Trends Cardiovasc Med 2019 Apr 30. Epub 2019 Apr 30.

Department of Cardiovascular & Metabolic Sciences, Cleveland Clinic, 9500 Euclid Avenue, M/S ND50, Cleveland, OH 44195, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10501738193005
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http://dx.doi.org/10.1016/j.tcm.2019.04.008DOI Listing
April 2019

Inflammation, Inflammasome Activation, and Atrial Fibrillation.

Circulation 2018 Nov;138(20):2243-2246

Departments of Molecular Cardiology, Lerner Research Institute (D.R.V.W., M.K.C.), Cleveland Clinic, OH.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.118.036143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6334772PMC
November 2018

PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity.

Authors:
Jessica van Setten Jennifer A Brody Yalda Jamshidi Brenton R Swenson Anne M Butler Harry Campbell Fabiola M Del Greco Daniel S Evans Quince Gibson Daniel F Gudbjartsson Kathleen F Kerr Bouwe P Krijthe Leo-Pekka Lyytikäinen Christian Müller Martina Müller-Nurasyid Ilja M Nolte Sandosh Padmanabhan Marylyn D Ritchie Antonietta Robino Albert V Smith Maristella Steri Toshiko Tanaka Alexander Teumer Stella Trompet Sheila Ulivi Niek Verweij Xiaoyan Yin David O Arnar Folkert W Asselbergs Joel S Bader John Barnard Josh Bis Stefan Blankenberg Eric Boerwinkle Yuki Bradford Brendan M Buckley Mina K Chung Dana Crawford Marcel den Hoed Josh C Denny Anna F Dominiczak Georg B Ehret Mark Eijgelsheim Patrick T Ellinor Stephan B Felix Oscar H Franco Lude Franke Tamara B Harris Hilma Holm Gandin Ilaria Annamaria Iorio Mika Kähönen Ivana Kolcic Jan A Kors Edward G Lakatta Lenore J Launer Honghuang Lin Henry J Lin Ruth J F Loos Steven A Lubitz Peter W Macfarlane Jared W Magnani Irene Mateo Leach Thomas Meitinger Braxton D Mitchell Thomas Munzel George J Papanicolaou Annette Peters Arne Pfeufer Peter P Pramstaller Olli T Raitakari Jerome I Rotter Igor Rudan Nilesh J Samani David Schlessinger Claudia T Silva Aldana Moritz F Sinner Jonathan D Smith Harold Snieder Elsayed Z Soliman Timothy D Spector David J Stott Konstantin Strauch Kirill V Tarasov Unnur Thorsteinsdottir Andre G Uitterlinden David R Van Wagoner Uwe Völker Henry Völzke Melanie Waldenberger Harm Jan Westra Philipp S Wild Tanja Zeller Alvaro Alonso Christy L Avery Stefania Bandinelli Emelia J Benjamin Francesco Cucca Marcus Dörr Luigi Ferrucci Paolo Gasparini Vilmundur Gudnason Caroline Hayward Susan R Heckbert Andrew A Hicks J Wouter Jukema Stefan Kääb Terho Lehtimäki Yongmei Liu Patricia B Munroe Afshin Parsa Ozren Polasek Bruce M Psaty Dan M Roden Renate B Schnabel Gianfranco Sinagra Kari Stefansson Bruno H Stricker Pim van der Harst Cornelia M van Duijn James F Wilson Sina A Gharib Paul I W de Bakker Aaron Isaacs Dan E Arking Nona Sotoodehnia

Nat Commun 2018 07 25;9(1):2904. Epub 2018 Jul 25.

Departments of Medicine and Epidemiology, Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, 98101, WA, USA.

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http://dx.doi.org/10.1038/s41467-018-04766-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060178PMC
July 2018

Multi-ethnic genome-wide association study for atrial fibrillation.

Authors:
Carolina Roselli Mark D Chaffin Lu-Chen Weng Stefanie Aeschbacher Gustav Ahlberg Christine M Albert Peter Almgren Alvaro Alonso Christopher D Anderson Krishna G Aragam Dan E Arking John Barnard Traci M Bartz Emelia J Benjamin Nathan A Bihlmeyer Joshua C Bis Heather L Bloom Eric Boerwinkle Erwin B Bottinger Jennifer A Brody Hugh Calkins Archie Campbell Thomas P Cappola John Carlquist Daniel I Chasman Lin Y Chen Yii-Der Ida Chen Eue-Keun Choi Seung Hoan Choi Ingrid E Christophersen Mina K Chung John W Cole David Conen James Cook Harry J Crijns Michael J Cutler Scott M Damrauer Brian R Daniels Dawood Darbar Graciela Delgado Joshua C Denny Martin Dichgans Marcus Dörr Elton A Dudink Samuel C Dudley Nada Esa Tonu Esko Markku Eskola Diane Fatkin Stephan B Felix Ian Ford Oscar H Franco Bastiaan Geelhoed Raji P Grewal Vilmundur Gudnason Xiuqing Guo Namrata Gupta Stefan Gustafsson Rebecca Gutmann Anders Hamsten Tamara B Harris Caroline Hayward Susan R Heckbert Jussi Hernesniemi Lynne J Hocking Albert Hofman Andrea R V R Horimoto Jie Huang Paul L Huang Jennifer Huffman Erik Ingelsson Esra Gucuk Ipek Kaoru Ito Jordi Jimenez-Conde Renee Johnson J Wouter Jukema Stefan Kääb Mika Kähönen Yoichiro Kamatani John P Kane Adnan Kastrati Sekar Kathiresan Petra Katschnig-Winter Maryam Kavousi Thorsten Kessler Bas L Kietselaer Paulus Kirchhof Marcus E Kleber Stacey Knight Jose E Krieger Michiaki Kubo Lenore J Launer Jari Laurikka Terho Lehtimäki Kirsten Leineweber Rozenn N Lemaitre Man Li Hong Euy Lim Henry J Lin Honghuang Lin Lars Lind Cecilia M Lindgren Marja-Liisa Lokki Barry London Ruth J F Loos Siew-Kee Low Yingchang Lu Leo-Pekka Lyytikäinen Peter W Macfarlane Patrik K Magnusson Anubha Mahajan Rainer Malik Alfredo J Mansur Gregory M Marcus Lauren Margolin Kenneth B Margulies Winfried März David D McManus Olle Melander Sanghamitra Mohanty Jay A Montgomery Michael P Morley Andrew P Morris Martina Müller-Nurasyid Andrea Natale Saman Nazarian Benjamin Neumann Christopher Newton-Cheh Maartje N Niemeijer Kjell Nikus Peter Nilsson Raymond Noordam Heidi Oellers Morten S Olesen Marju Orho-Melander Sandosh Padmanabhan Hui-Nam Pak Guillaume Paré Nancy L Pedersen Joanna Pera Alexandre Pereira David Porteous Bruce M Psaty Sara L Pulit Clive R Pullinger Daniel J Rader Lena Refsgaard Marta Ribasés Paul M Ridker Michiel Rienstra Lorenz Risch Dan M Roden Jonathan Rosand Michael A Rosenberg Natalia Rost Jerome I Rotter Samir Saba Roopinder K Sandhu Renate B Schnabel Katharina Schramm Heribert Schunkert Claudia Schurman Stuart A Scott Ilkka Seppälä Christian Shaffer Svati Shah Alaa A Shalaby Jaemin Shim M Benjamin Shoemaker Joylene E Siland Juha Sinisalo Moritz F Sinner Agnieszka Slowik Albert V Smith Blair H Smith J Gustav Smith Jonathan D Smith Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Bruno H Stricker Albert Sun Han Sun Jesper H Svendsen Toshihiro Tanaka Kahraman Tanriverdi Kent D Taylor Maris Teder-Laving Alexander Teumer Sébastien Thériault Stella Trompet Nathan R Tucker Arnljot Tveit Andre G Uitterlinden Pim Van Der Harst Isabelle C Van Gelder David R Van Wagoner Niek Verweij Efthymia Vlachopoulou Uwe Völker Biqi Wang Peter E Weeke Bob Weijs Raul Weiss Stefan Weiss Quinn S Wells Kerri L Wiggins Jorge A Wong Daniel Woo Bradford B Worrall Pil-Sung Yang Jie Yao Zachary T Yoneda Tanja Zeller Lingyao Zeng Steven A Lubitz Kathryn L Lunetta Patrick T Ellinor

Nat Genet 2018 06 11;50(9):1225-1233. Epub 2018 Jun 11.

Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, MA, USA.

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http://dx.doi.org/10.1038/s41588-018-0133-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6136836PMC
June 2018

Genetic Control of Left Atrial Gene Expression Yields Insights into the Genetic Susceptibility for Atrial Fibrillation.

Circ Genom Precis Med 2018 03;11(3):e002107

From the Departments of Cellular and Molecular Medicine (J.H., G.T., J.D.S.), Quantitative Health Sciences (J.B.), Molecular Cardiology (S.G.-P., L.C., B.L., C.S.M., D.R.V.W., M.K.C.), Cardiovascular Medicine (C.S.M., D.R.V.W., M.K.C., J.D.S.), and Cardiothoracic Surgery (G.B.P., E.E.R., A.M.G., K.R.M., N.G.S.), Cleveland Clinic, Cleveland, OH.

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http://dx.doi.org/10.1161/CIRCGEN.118.002107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858469PMC
March 2018

Genetic Interactions with Age, Sex, Body Mass Index, and Hypertension in Relation to Atrial Fibrillation: The AFGen Consortium.

Sci Rep 2017 09 12;7(1):11303. Epub 2017 Sep 12.

Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41598-017-09396-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5595875PMC
September 2017

Genetic-Genomic Insights Into the Metabolic Determinants of Spontaneous Atrial Fibrillation.

Circ Arrhythm Electrophysiol 2017 08;10(8)

From the Department of Molecular Cardiology, Cleveland Clinic, OH.

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http://dx.doi.org/10.1161/CIRCEP.117.005636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673115PMC
August 2017

Erratum: Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

Authors:
Ingrid E Christophersen Michiel Rienstra Carolina Roselli Xiaoyan Yin Bastiaan Geelhoed John Barnard Honghuang Lin Dan E Arking Albert V Smith Christine M Albert Mark Chaffin Nathan R Tucker Molong Li Derek Klarin Nathan A Bihlmeyer Siew-Kee Low Peter E Weeke Martina Müller-Nurasyid J Gustav Smith Jennifer A Brody Maartje N Niemeijer Marcus Dörr Stella Trompet Jennifer Huffman Stefan Gustafsson Claudia Schurmann Marcus E Kleber Leo-Pekka Lyytikäinen Ilkka Seppälä Rainer Malik Andrea R V R Horimoto Marco Perez Juha Sinisalo Stefanie Aeschbacher Sébastien Thériault Jie Yao Farid Radmanesh Stefan Weiss Alexander Teumer Seung Hoan Choi Lu-Chen Weng Sebastian Clauss Rajat Deo Daniel J Rader Svati H Shah Albert Sun Jemma C Hopewell Stephanie Debette Ganesh Chauhan Qiong Yang Bradford B Worrall Guillaume Paré Yoichiro Kamatani Yanick P Hagemeijer Niek Verweij Joylene E Siland Michiaki Kubo Jonathan D Smith David R Van Wagoner Joshua C Bis Siegfried Perz Bruce M Psaty Paul M Ridker Jared W Magnani Tamara B Harris Lenore J Launer M Benjamin Shoemaker Sandosh Padmanabhan Jeffrey Haessler Traci M Bartz Melanie Waldenberger Peter Lichtner Marina Arendt Jose E Krieger Mika Kähönen Lorenz Risch Alfredo J Mansur Annette Peters Blair H Smith Lars Lind Stuart A Scott Yingchang Lu Erwin B Bottinger Jussi Hernesniemi Cecilia M Lindgren Jorge A Wong Jie Huang Markku Eskola Andrew P Morris Ian Ford Alex P Reiner Graciela Delgado Lin Y Chen Yii-Der Ida Chen Roopinder K Sandhu Man Li Eric Boerwinkle Lewin Eisele Lars Lannfelt Natalia Rost Christopher D Anderson Kent D Taylor Archie Campbell Patrik K Magnusson David Porteous Lynne J Hocking Efthymia Vlachopoulou Nancy L Pedersen Kjell Nikus Marju Orho-Melander Anders Hamsten Jan Heeringa Joshua C Denny Jennifer Kriebel Dawood Darbar Christopher Newton-Cheh Christian Shaffer Peter W Macfarlane Stefanie Heilmann-Heimbach Peter Almgren Paul L Huang Nona Sotoodehnia Elsayed Z Soliman Andre G Uitterlinden Albert Hofman Oscar H Franco Uwe Völker Karl-Heinz Jöckel Moritz F Sinner Henry J Lin Xiuqing Guo Martin Dichgans Erik Ingelsson Charles Kooperberg Olle Melander Ruth J F Loos Jari Laurikka David Conen Jonathan Rosand Pim van der Harst Marja-Liisa Lokki Sekar Kathiresan Alexandre Pereira J Wouter Jukema Caroline Hayward Jerome I Rotter Winfried März Terho Lehtimäki Bruno H Stricker Mina K Chung Stephan B Felix Vilmundur Gudnason Alvaro Alonso Dan M Roden Stefan Kääb Daniel I Chasman Susan R Heckbert Emelia J Benjamin Toshihiro Tanaka Kathryn L Lunetta Steven A Lubitz Patrick T Ellinor

Nat Genet 2017 07;49(8):1286

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http://dx.doi.org/10.1038/ng0817-1286cDOI Listing
July 2017

Large-scale analyses of common and rare variants identify 12 new loci associated with atrial fibrillation.

Authors:
Ingrid E Christophersen Michiel Rienstra Carolina Roselli Xiaoyan Yin Bastiaan Geelhoed John Barnard Honghuang Lin Dan E Arking Albert V Smith Christine M Albert Mark Chaffin Nathan R Tucker Molong Li Derek Klarin Nathan A Bihlmeyer Siew-Kee Low Peter E Weeke Martina Müller-Nurasyid J Gustav Smith Jennifer A Brody Maartje N Niemeijer Marcus Dörr Stella Trompet Jennifer Huffman Stefan Gustafsson Claudia Schurmann Marcus E Kleber Leo-Pekka Lyytikäinen Ilkka Seppälä Rainer Malik Andrea R V R Horimoto Marco Perez Juha Sinisalo Stefanie Aeschbacher Sébastien Thériault Jie Yao Farid Radmanesh Stefan Weiss Alexander Teumer Seung Hoan Choi Lu-Chen Weng Sebastian Clauss Rajat Deo Daniel J Rader Svati H Shah Albert Sun Jemma C Hopewell Stephanie Debette Ganesh Chauhan Qiong Yang Bradford B Worrall Guillaume Paré Yoichiro Kamatani Yanick P Hagemeijer Niek Verweij Joylene E Siland Michiaki Kubo Jonathan D Smith David R Van Wagoner Joshua C Bis Siegfried Perz Bruce M Psaty Paul M Ridker Jared W Magnani Tamara B Harris Lenore J Launer M Benjamin Shoemaker Sandosh Padmanabhan Jeffrey Haessler Traci M Bartz Melanie Waldenberger Peter Lichtner Marina Arendt Jose E Krieger Mika Kähönen Lorenz Risch Alfredo J Mansur Annette Peters Blair H Smith Lars Lind Stuart A Scott Yingchang Lu Erwin B Bottinger Jussi Hernesniemi Cecilia M Lindgren Jorge A Wong Jie Huang Markku Eskola Andrew P Morris Ian Ford Alex P Reiner Graciela Delgado Lin Y Chen Yii-Der Ida Chen Roopinder K Sandhu Man Li Eric Boerwinkle Lewin Eisele Lars Lannfelt Natalia Rost Christopher D Anderson Kent D Taylor Archie Campbell Patrik K Magnusson David Porteous Lynne J Hocking Efthymia Vlachopoulou Nancy L Pedersen Kjell Nikus Marju Orho-Melander Anders Hamsten Jan Heeringa Joshua C Denny Jennifer Kriebel Dawood Darbar Christopher Newton-Cheh Christian Shaffer Peter W Macfarlane Stefanie Heilmann-Heimbach Peter Almgren Paul L Huang Nona Sotoodehnia Elsayed Z Soliman Andre G Uitterlinden Albert Hofman Oscar H Franco Uwe Völker Karl-Heinz Jöckel Moritz F Sinner Henry J Lin Xiuqing Guo Martin Dichgans Erik Ingelsson Charles Kooperberg Olle Melander Ruth J F Loos Jari Laurikka David Conen Jonathan Rosand Pim van der Harst Marja-Liisa Lokki Sekar Kathiresan Alexandre Pereira J Wouter Jukema Caroline Hayward Jerome I Rotter Winfried März Terho Lehtimäki Bruno H Stricker Mina K Chung Stephan B Felix Vilmundur Gudnason Alvaro Alonso Dan M Roden Stefan Kääb Daniel I Chasman Susan R Heckbert Emelia J Benjamin Toshihiro Tanaka Kathryn L Lunetta Steven A Lubitz Patrick T Ellinor

Nat Genet 2017 Jun 17;49(6):946-952. Epub 2017 Apr 17.

Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3843DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5585859PMC
June 2017

Is Left Atrial Size a Predictor of Mortality after Coronary Artery Bypass Surgery? A Single Center Study.

Acta Cardiol Sin 2017 Mar;33(2):195-203

Department of Molecular Cardiology, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5364162PMC
March 2017

OSA and Cardiac Arrhythmogenesis: Mechanistic Insights.

Chest 2017 Jan 29;151(1):225-241. Epub 2016 Sep 29.

Neurologic Institute, Respiratory Institute, Heart and Vascular Institute and Molecular Cardiology Department, Lerner Research Institute, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH.

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http://dx.doi.org/10.1016/j.chest.2016.09.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5989643PMC
January 2017

Adenosine-Induced Atrial Fibrillation: Localized Reentrant Drivers in Lateral Right Atria due to Heterogeneous Expression of Adenosine A1 Receptors and GIRK4 Subunits in the Human Heart.

Circulation 2016 Aug 26;134(6):486-98. Epub 2016 Jul 26.

From Department of Physiology & Cell Biology, The Ohio State University Wexner Medical Center, Columbus (N.L., T.A.C., B.J.H., L.V.S., A. Kalyanasundaram, S.O.Z., A.G., P.J.M., P.M.L.J., B.J.B., V.V.F.); Davis Heart & Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus (N.L., T.A.C., B.J.H., L.V.S., A. Kalyanasundaram, A. Kilic, P.J.M., P.M.L.J., B.J.B., J.D.H., R.W., V.V.F.); Auckland Bioengineering Institute, The University of Auckland, New Zealand (J.Z.); Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus (A.G., A. Kilic, P.J.M., P.M.L.J., J.D.H., R.W.); Department of Molecular Cardiology, Cleveland Clinic, OH (D.R.V.W.); and Department of Surgery, Division of Cardiac Surgery, Wexner Medical Center, The Ohio State University, Columbus (A. Kilic, J.D.H., R.W.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.021165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980184PMC
August 2016

PANCR, the PITX2 Adjacent Noncoding RNA, Is Expressed in Human Left Atria and Regulates PITX2c Expression.

Circ Arrhythm Electrophysiol 2016 Jan;9(1):e003197

From the Department of Molecular Cardiology, Lerner Research Institute (S.R.G.-P., C.S.M., D.R.V.W., M.K.C.), Department of Cellular & Molecular Medicine, Lerner Research Institute (S.R.G.-P., J.H., J.D.S.), Department of Quantitative Health Sciences (J.B.), and Department of Cardiovascular Medicine (C.S.M., D.R.V.W., M.K.C., J.D.S.), Cleveland Clinic, OH.

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http://dx.doi.org/10.1161/CIRCEP.115.003197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4719779PMC
January 2016

Oxidant and Inflammatory Mechanisms and Targeted Therapy in Atrial Fibrillation: An Update.

J Cardiovasc Pharmacol 2015 Dec;66(6):523-9

Department of Molecular Cardiology, Cleveland Clinic Foundation, Cleveland, OH.

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http://dx.doi.org/10.1097/FJC.0000000000000313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4674316PMC
December 2015

Rapid multislice T1 mapping of mouse myocardium: Application to quantification of manganese uptake in α-Dystrobrevin knockout mice.

Magn Reson Med 2015 Nov 18;74(5):1370-9. Epub 2014 Nov 18.

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1002/mrm.25533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4436091PMC
November 2015

Role of inflammation in atrial fibrillation pathophysiology and management.

Circ J 2015 16;79(3):495-502. Epub 2015 Feb 16.

Department of Cardiology, Fujita Health University School of Medicine.

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http://dx.doi.org/10.1253/circj.CJ-15-0138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4457364PMC
November 2015

How Does Diazoxide Elicit Arrhythmias in Rats With Type 2 Diabetes?: Is This Effect Clinically Significant?

J Am Coll Cardiol 2015 Sep;66(10):1157-9

Department of Molecular Cardiology, Cleveland Clinic, Cleveland, Ohio. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2015.07.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339602PMC
September 2015

Are SK channels a logical target for treating ventricular arrhythmias? First, do no harm.

Trends Cardiovasc Med 2015 Aug 5;25(6):515-6. Epub 2015 Mar 5.

Cleveland Clinic Department of Molecular Cardiology, Cleveland, OH. Electronic address:

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http://dx.doi.org/10.1016/j.tcm.2015.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540062PMC
August 2015

What currents underlie pulmonary vein automaticity?

J Cardiovasc Electrophysiol 2015 Mar 13;26(3):320-1. Epub 2015 Jan 13.

Cleveland Clinic, Department of Molecular Cardiology, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1111/jce.12595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4429253PMC
March 2015

Left atrial transcriptional changes associated with atrial fibrillation susceptibility and persistence.

Circ Arrhythm Electrophysiol 2015 Feb 18;8(1):32-41. Epub 2014 Dec 18.

From the Department of Medicine, University of Chicago, IL (A.D.); Department of Quantitative Health Sciences (J.B; H.S.), Department of Molecular Cardiology (L.C., D.R.V.W., M.K.C.), and Department of Cellular and Molecular Medicine, Cleveland Clinic (J.D.S.), Lerner Research Institute, OH; Department of Cardiovascular Medicine (D.N., C.M., J.D.S., M.K.C.) and Department of Cardiovascular Medicine and Thoracic and Cardiovascular Surgery (G.P., D.J., E.R., A.M.G., K.M.), Heart and Vascular Institute, Cleveland, OH; and Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, OH (C.M., J.D.S., D.R.V.W., M.K.C.).

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http://dx.doi.org/10.1161/CIRCEP.114.001632DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334691PMC
February 2015

Atrial Fibrillation associated chromosome 4q25 variants are not associated with PITX2c expression in human adult left atrial appendages.

PLoS One 2014 22;9(1):e86245. Epub 2014 Jan 22.

Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, Ohio, United States of America ; Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, Ohio, United States of America ; Department of Molecular Cardiology, Cleveland Clinic, Cleveland, Ohio, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0086245PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3899225PMC
November 2014

Attenuated response of L-type calcium current to nitric oxide in atrial fibrillation.

Cardiovasc Res 2014 Mar 12;101(3):533-42. Epub 2013 Dec 12.

Department of Pharmacology and Toxicology, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1093/cvr/cvt334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4014863PMC
March 2014

Impact of vagal nerve stimulation on left atrial structure and function in a canine high-rate pacing model.

Circ Heart Fail 2014 Mar 7;7(2):320-6. Epub 2014 Jan 7.

Departments of Cardiovascular Medicine and Molecular Cardiology, Cleveland Clinic, OH; and New York Institute of Technology College of Osteopathic Medicine, Old Westbury.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.113.000937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056587PMC
March 2014

Impact of aldosterone antagonists on the substrate for atrial fibrillation: aldosterone promotes oxidative stress and atrial structural/electrical remodeling.

Int J Cardiol 2013 Oct 15;168(6):5135-42. Epub 2013 Aug 15.

Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Jordan. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2013.08.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062912PMC
October 2013

Baroreflex stimulation versus renal denervation for treatment of hypertension: what constitutes a logical comparison of these interventions on atrial electrophysiology?

J Cardiovasc Electrophysiol 2013 Sep 17;24(9):1034-6. Epub 2013 Jun 17.

Department of Clinical Pharmacy, Faculty of Pharmacy, Jordan University of Science and Technology, Irbid, Jordan.

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http://dx.doi.org/10.1111/jce.12185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770820PMC
September 2013

Cardiac autonomic nerve stimulation in the treatment of heart failure.

Ann Thorac Surg 2013 Jul 5;96(1):339-45. Epub 2013 Jun 5.

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1016/j.athoracsur.2012.12.060DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4088261PMC
July 2013

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment.

Authors:
Cornelius A Rietveld Sarah E Medland Jaime Derringer Jian Yang Tõnu Esko Nicolas W Martin Harm-Jan Westra Konstantin Shakhbazov Abdel Abdellaoui Arpana Agrawal Eva Albrecht Behrooz Z Alizadeh Najaf Amin John Barnard Sebastian E Baumeister Kelly S Benke Lawrence F Bielak Jeffrey A Boatman Patricia A Boyle Gail Davies Christiaan de Leeuw Niina Eklund Daniel S Evans Rudolf Ferhmann Krista Fischer Christian Gieger Håkon K Gjessing Sara Hägg Jennifer R Harris Caroline Hayward Christina Holzapfel Carla A Ibrahim-Verbaas Erik Ingelsson Bo Jacobsson Peter K Joshi Astanand Jugessur Marika Kaakinen Stavroula Kanoni Juha Karjalainen Ivana Kolcic Kati Kristiansson Zoltán Kutalik Jari Lahti Sang H Lee Peng Lin Penelope A Lind Yongmei Liu Kurt Lohman Marisa Loitfelder George McMahon Pedro Marques Vidal Osorio Meirelles Lili Milani Ronny Myhre Marja-Liisa Nuotio Christopher J Oldmeadow Katja E Petrovic Wouter J Peyrot Ozren Polasek Lydia Quaye Eva Reinmaa John P Rice Thais S Rizzi Helena Schmidt Reinhold Schmidt Albert V Smith Jennifer A Smith Toshiko Tanaka Antonio Terracciano Matthijs J H M van der Loos Veronique Vitart Henry Völzke Jürgen Wellmann Lei Yu Wei Zhao Jüri Allik John R Attia Stefania Bandinelli François Bastardot Jonathan Beauchamp David A Bennett Klaus Berger Laura J Bierut Dorret I Boomsma Ute Bültmann Harry Campbell Christopher F Chabris Lynn Cherkas Mina K Chung Francesco Cucca Mariza de Andrade Philip L De Jager Jan-Emmanuel De Neve Ian J Deary George V Dedoussis Panos Deloukas Maria Dimitriou Guðny Eiríksdóttir Martin F Elderson Johan G Eriksson David M Evans Jessica D Faul Luigi Ferrucci Melissa E Garcia Henrik Grönberg Vilmundur Guðnason Per Hall Juliette M Harris Tamara B Harris Nicholas D Hastie Andrew C Heath Dena G Hernandez Wolfgang Hoffmann Adriaan Hofman Rolf Holle Elizabeth G Holliday Jouke-Jan Hottenga William G Iacono Thomas Illig Marjo-Riitta Järvelin Mika Kähönen Jaakko Kaprio Robert M Kirkpatrick Matthew Kowgier Antti Latvala Lenore J Launer Debbie A Lawlor Terho Lehtimäki Jingmei Li Paul Lichtenstein Peter Lichtner David C Liewald Pamela A Madden Patrik K E Magnusson Tomi E Mäkinen Marco Masala Matt McGue Andres Metspalu Andreas Mielck Michael B Miller Grant W Montgomery Sutapa Mukherjee Dale R Nyholt Ben A Oostra Lyle J Palmer Aarno Palotie Brenda W J H Penninx Markus Perola Patricia A Peyser Martin Preisig Katri Räikkönen Olli T Raitakari Anu Realo Susan M Ring Samuli Ripatti Fernando Rivadeneira Igor Rudan Aldo Rustichini Veikko Salomaa Antti-Pekka Sarin David Schlessinger Rodney J Scott Harold Snieder Beate St Pourcain John M Starr Jae Hoon Sul Ida Surakka Rauli Svento Alexander Teumer Henning Tiemeier Frank J A van Rooij David R Van Wagoner Erkki Vartiainen Jorma Viikari Peter Vollenweider Judith M Vonk Gérard Waeber David R Weir H-Erich Wichmann Elisabeth Widen Gonneke Willemsen James F Wilson Alan F Wright Dalton Conley George Davey-Smith Lude Franke Patrick J F Groenen Albert Hofman Magnus Johannesson Sharon L R Kardia Robert F Krueger David Laibson Nicholas G Martin Michelle N Meyer Danielle Posthuma A Roy Thurik Nicholas J Timpson André G Uitterlinden Cornelia M van Duijn Peter M Visscher Daniel J Benjamin David Cesarini Philipp D Koellinger

Science 2013 Jun 30;340(6139):1467-71. Epub 2013 May 30.

Department of Applied Economics, Erasmus School of Economics, Erasmus University Rotterdam, Rotterdam, Netherlands.

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http://dx.doi.org/10.1126/science.1235488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3751588PMC
June 2013

Effect of epivascular cardiac autonomic nerve stimulation on cardiac function.

Ann Thorac Surg 2012 Oct 29;94(4):1150-6. Epub 2012 Aug 29.

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1016/j.athoracsur.2012.04.092DOI Listing
October 2012

There is power in numbers--even/especially in genomic medicine.

Can J Cardiol 2012 Mar-Apr;28(2):158-9. Epub 2012 Feb 9.

Cleveland Clinic Departments of Molecular Cardiology and Cardiovascular Medicine, Cleveland, Ohio, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S0828282X1200035
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http://dx.doi.org/10.1016/j.cjca.2012.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674099PMC
July 2012

Whole genome expression differences in human left and right atria ascertained by RNA sequencing.

Circ Cardiovasc Genet 2012 Jun 3;5(3):327-35. Epub 2012 Apr 3.

Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, OH, USA.

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http://dx.doi.org/10.1161/CIRCGENETICS.111.961631DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380143PMC
June 2012

Meta-analysis identifies six new susceptibility loci for atrial fibrillation.

Nat Genet 2012 Apr 29;44(6):670-5. Epub 2012 Apr 29.

Cardiovascular Research Center, Massachusetts General Hospital, Charlestown, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.2261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366038PMC
April 2012

Influence of race on atrial fibrillation after cardiac surgery.

Circ Arrhythm Electrophysiol 2011 Oct 13;4(5):644-52. Epub 2011 Aug 13.

Heart and Vascular Center, Case Western Reserve University, MetroHealth Campus, Cleveland, OH 44118, USA.

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http://dx.doi.org/10.1161/CIRCEP.111.962670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201706PMC
October 2011

Left-to-right atrial inward rectifier potassium current gradients in patients with paroxysmal versus chronic atrial fibrillation.

Circ Arrhythm Electrophysiol 2010 Oct 24;3(5):472-80. Epub 2010 Jul 24.

Department of Pharmacology and Toxicology, Dresden University of Technology, Dresden, Germany.

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http://dx.doi.org/10.1161/CIRCEP.110.954636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5832445PMC
October 2010

Association of left atrial endothelin-1 with atrial rhythm, size, and fibrosis in patients with structural heart disease.

Circ Arrhythm Electrophysiol 2010 Aug 21;3(4):369-79. Epub 2010 May 21.

Department of Molecular Cardiology, Cleveland Clinic, 9500 Euclid Ave., Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1161/CIRCEP.109.924985DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050013PMC
August 2010

Preoperative angiotensin-blocking drug therapy is not associated with atrial fibrillation after cardiac surgery.

Am Heart J 2010 Aug;160(2):329-336.e1

Heart and Vascular Research Center, Case Western Reserve University, MetroHealth Campus, Cleveland, OH, USA.

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http://dx.doi.org/10.1016/j.ahj.2010.05.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2919305PMC
August 2010

Left atrial epicardial adiposity and atrial fibrillation.

Circ Arrhythm Electrophysiol 2010 Jun 26;3(3):230-6. Epub 2010 May 26.

Departments of General Internal Medicine, Cardiovascular Medicine, and Diagnostic Radiology, the Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1161/CIRCEP.110.957241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2974566PMC
June 2010

Common variants in KCNN3 are associated with lone atrial fibrillation.

Nat Genet 2010 Mar 21;42(3):240-4. Epub 2010 Feb 21.

[1] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts, USA. [3] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [4] These authors contributed equally to this work.

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http://dx.doi.org/10.1038/ng.537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2871387PMC
March 2010

Chronic vagus nerve stimulation improves autonomic control and attenuates systemic inflammation and heart failure progression in a canine high-rate pacing model.

Circ Heart Fail 2009 Nov 22;2(6):692-9. Epub 2009 Sep 22.

Department of Molecular Cardiology and Cardiovascular Medicine, Cleveland Clinic, USA.

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http://dx.doi.org/10.1161/CIRCHEARTFAILURE.109.873968DOI Listing
November 2009

Impact of dietary fatty acids on cardiac arrhythmogenesis.

Circ Arrhythm Electrophysiol 2009 Aug;2(4):460-9

Department of Molecular Cardiology, The Cleveland Clinic, Cleveland, Ohio 44195, USA.

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https://www.ahajournals.org/doi/10.1161/CIRCEP.109.880773
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http://dx.doi.org/10.1161/CIRCEP.109.880773DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831114PMC
August 2009

L-type calcium channel blockers exert an antiinflammatory effect by suppressing expression of plasminogen receptors on macrophages.

Circ Res 2009 Jul 11;105(2):167-75. Epub 2009 Jun 11.

Department of Molecular Cardiology, Lerner Research Institute, Cleveland Clinic, 9500 Euclid Ave/NB50, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1161/CIRCRESAHA.109.200311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2745969PMC
July 2009

Oxidative stress and inflammation in atrial fibrillation: role in pathogenesis and potential as a therapeutic target.

J Cardiovasc Pharmacol 2008 Oct;52(4):306-13

Department of Molecular Cardiology, Cleveland Clinic, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1097/FJC.0b013e31817f9398DOI Listing
October 2008

Elucidation of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement.

Mol Biol Cell 2008 Aug 21;19(8):3203-11. Epub 2008 May 21.

Department of Biomedical Engineering, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1091/mbc.e07-08-0765DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2488296PMC
August 2008

Is homocysteine a mediator of atrial dysfunction or just another marker of endothelial dysfunction?

Europace 2008 Aug 30;10(8):899-900. Epub 2008 Jun 30.

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http://dx.doi.org/10.1093/europace/eun182DOI Listing
August 2008

Evaluating the impact of atrial dilatation on atrial calcium cycling.

Eur Heart J 2008 May 7;29(9):1084-5. Epub 2008 Apr 7.

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http://dx.doi.org/10.1093/eurheartj/ehn051DOI Listing
May 2008

Better never than late? New insights into a mechanism linking metabolic stress to altered cardiac repolarization.

J Mol Cell Cardiol 2008 Feb 15;44(2):238-40. Epub 2007 Dec 15.

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http://dx.doi.org/10.1016/j.yjmcc.2007.12.004DOI Listing
February 2008

Prednisone prevents inducible atrial flutter in the canine sterile pericarditis model.

J Cardiovasc Electrophysiol 2008 Jan 24;19(1):74-81. Epub 2007 Sep 24.

Division of Cardiology, Department of Medicine, Case Western Reserve University, University Hospitals of Cleveland, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1111/j.1540-8167.2007.00970.xDOI Listing
January 2008

Atrial glutathione content, calcium current, and contractility.

J Biol Chem 2007 Sep 25;282(38):28063-73. Epub 2007 Jul 25.

College of Pharmacy, Ohio State University, Columbus, Ohio 43210, USA.

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http://dx.doi.org/10.1074/jbc.M704893200DOI Listing
September 2007

Effects of sterile pericarditis on connexins 40 and 43 in the atria: correlation with abnormal conduction and atrial arrhythmias.

Am J Physiol Heart Circ Physiol 2007 Aug 13;293(2):H1231-41. Epub 2007 Apr 13.

Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1152/ajpheart.00607.2006DOI Listing
August 2007

Recent insights into the pathophysiology of atrial fibrillation.

Semin Thorac Cardiovasc Surg 2007 ;19(1):9-15

Department of Molecular Cardiology, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1053/j.semtcvs.2007.01.006DOI Listing
July 2007

Effect of dexamethasone on atrial fibrillation after cardiac surgery: prospective, randomized, double-blind, placebo-controlled trial.

J Cardiothorac Vasc Anesth 2007 Feb 14;21(1):68-75. Epub 2006 Feb 14.

Department of Cardiothoracic Anesthesiology, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1053/j.jvca.2005.10.014DOI Listing
February 2007

An experimental rabbit model for off-pump left ventricular reconstruction following left ventricular aneurysm.

Heart Surg Forum 2006 ;9(5):E786-91

Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.

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January 2007

Localization of Kv1.5 channels in rat and canine myocyte sarcolemma.

FEBS Lett 2006 Nov 12;580(26):6039-46. Epub 2006 Oct 12.

Department of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, 2350 Health Sciences Mall, Vancouver, BC, Canada V6T 1Z3.

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http://dx.doi.org/10.1016/j.febslet.2006.09.069DOI Listing
November 2006

Red cell transfusion is associated with an increased risk for postoperative atrial fibrillation.

Ann Thorac Surg 2006 Nov;82(5):1747-56

Department of Cardiothoracic Anesthesia, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1016/j.athoracsur.2006.05.045DOI Listing
November 2006

Metaboelectric signaling in the diseased heart.

J Mol Cell Cardiol 2006 Mar 23;40(3):333-4. Epub 2006 Jan 23.

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http://dx.doi.org/10.1016/j.yjmcc.2005.12.006DOI Listing
March 2006

Relation of C-reactive protein correlates with risk of thromboembolism in patients with atrial fibrillation.

Am J Cardiol 2004 Sep;94(6):805-7

Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1016/j.amjcard.2004.06.011DOI Listing
September 2004