David R Mack

David R Mack

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Anticipatory care of children and adolescents with inflammatory bowel disease: a primer for primary care providers.

Curr Opin Pediatr 2019 Oct;31(5):654-660

CHEO Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Eastern Ontario.

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http://dx.doi.org/10.1097/MOP.0000000000000795DOI Listing
October 2019

Canadian Association of Gastroenterology Clinical Practice Guideline for the Medical Management of Pediatric Luminal Crohn's Disease.

Gastroenterology 2019 08 15;157(2):320-348. Epub 2019 Jul 15.

Ch.I.L.D. Foundation Canadian Children IBD Network, Vancouver, British Columbia, Canada; IBD Centre, Department of Paediatrics, SickKids Hospital, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.03.022DOI Listing
August 2019

Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation.

Gastroenterology 2019 06 16;156(8):2254-2265.e3. Epub 2019 Feb 16.

Genetics and Molecular Biology Program, Emory University, Atlanta, Georgia; Division of Pediatric Gastroenterology, Department of Pediatrics, Emory University School of Medicine and Children's Healthcare of Atlanta, Atlanta, Georgia; Department of Human Genetics, Emory University, Atlanta, Georgia. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.01.270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6529254PMC
June 2019

The pediatric inflammatory bowel disease INTERMED: A new clinical tool to assess psychosocial needs.

J Psychosom Res 2019 Apr 6;119:26-33. Epub 2019 Feb 6.

CHEO Research Institute, Ottawa, ON, Canada; Department of Pediatrics, University of Ottawa, Ottawa, ON, Canada; CHEO Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology & Nutrition, Ottawa, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychores.2019.02.002DOI Listing
April 2019

Health Services Use during Transition from Pediatric to Adult Care for Inflammatory Bowel Disease: A Population-Based Study Using Health Administrative Data.

J Pediatr 2018 12 25;203:280-287.e4. Epub 2018 Sep 25.

Children's Hospital of Eastern Ontario IBD Centre, Division of Gastroenterology, Hepatology and Nutrition, CHEO Research Institute, Children's Hospital of Eastern Ontario, Ottawa, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Canada; Institute for Clinical Evaluative Sciences, Toronto, Canada; Department of Pediatrics, University of Ottawa, Ottawa, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2018.08.021DOI Listing
December 2018

Biologics Delay Progression of Crohn's Disease, but Not Early Surgery, in Children.

Clin Gastroenterol Hepatol 2018 09 2;16(9):1467-1473. Epub 2018 Mar 2.

Pediatric Gastroenterology and Nutrition, Hasbro Children Hospital, Providence, Rhode Island; The Warren Alpert Medical School, Brown University, Providence, Rhode Island. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2018.02.027DOI Listing
September 2018

Mucosal-luminal interface proteomics reveals biomarkers of pediatric inflammatory bowel disease-associated colitis.

Am J Gastroenterol 2018 05 12;113(5):713-724. Epub 2018 Mar 12.

Ottawa Institute of Systems Biology and Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, ON, Canada. Children's Hospital of Eastern Ontario (CHEO) Inflammatory Bowel Disease Centre and CHEO Research Institute, Ottawa, ON, Canada. Department of Pediatrics CHEO, Ottawa, ON, Canada. School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Canada. Department of Chemistry and Biomolecular Sciences, University of Ottawa, Ottawa, Canada. Canadian Institute for Advanced Research, 180 Dundas Street West, Toronto, ON, M5G 1Z8, Canada. Shelley A. Deeke and Amanda E. Starr shared co-first authorship.

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http://dx.doi.org/10.1038/s41395-018-0024-9DOI Listing
May 2018

Therapeutic Drug Monitoring in Pediatric Inflammatory Bowel Disease.

Curr Gastroenterol Rep 2018 Apr 5;20(5):18. Epub 2018 Apr 5.

CHEO Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON, K1H 8L1, Canada.

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http://dx.doi.org/10.1007/s11894-018-0623-zDOI Listing
April 2018

Human Microbiome and Learning Healthcare Systems: Integrating Research and Precision Medicine for Inflammatory Bowel Disease.

OMICS 2018 02 10;22(2):119-126. Epub 2017 Mar 10.

1 Department of Psychology, University of Guelph , Guelph, Ontario, Canada .

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http://dx.doi.org/10.1089/omi.2016.0185DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810428PMC
February 2018

Increased bone matrix mineralization in treatment-naïve children with inflammatory bowel disease.

Bone 2017 Dec 10;105:50-56. Epub 2017 Jul 10.

Children's Hospital of Eastern Ontario (CHEO) Research Institute, Ottawa, Ontario, Canada; Department of Paediatrics, University of Ottawa, Canada.

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http://dx.doi.org/10.1016/j.bone.2017.07.011DOI Listing
December 2017

Value of upper endoscopic biopsies in predicting medical refractoriness in pediatric patients with ulcerative colitis.

Hum Pathol 2017 08 23;66:167-176. Epub 2017 Jun 23.

Department of Pathology, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada K1H 8L1; Faculty of Medicine, Public Health and Preventative Medicine, University of Ottawa, Ottawa, ON, Canada K1H 8M5. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2017.06.006DOI Listing
August 2017

Health Services Utilization, Specialist Care, and Time to Diagnosis with Inflammatory Bowel Disease in Immigrants to Ontario, Canada: A Population-Based Cohort Study.

Inflamm Bowel Dis 2016 10;22(10):2482-90

*Children's Hospital of Eastern Ontario IBD Centre, Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada; †Department of Pediatrics, University of Ottawa, Ottawa, Ontario, Canada; ‡School of Epidemiology, Public Health and Preventive Medicine, University of Ottawa, Ottawa, Ontario, Canada; §Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada; ‖Ottawa Hospital Research Institute, Ottawa, Ontario, Canada; ¶Department of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada; **Mount Sinai Centre for Inflammatory Bowel Disease, Mount Sinai Hospital, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada; ††Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada; Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada; and ‡‡Division of Paediatric Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/MIB.0000000000000905DOI Listing
October 2016

In Vitro Metabolic Labeling of Intestinal Microbiota for Quantitative Metaproteomics.

Anal Chem 2016 06 3;88(12):6120-5. Epub 2016 Jun 3.

Ottawa Institute of Systems Biology and Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa , Ottawa, Ontario, Canada , K1H 8M5.

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http://dx.doi.org/10.1021/acs.analchem.6b01412DOI Listing
June 2016

Asthma, type 1 and type 2 diabetes mellitus, and inflammatory bowel disease amongst South Asian immigrants to Canada and their children: a population-based cohort study.

PLoS One 2015 7;10(4):e0123599. Epub 2015 Apr 7.

Institute for Clinical Evaluative Sciences, Toronto, Canada; Division of Pediatric Medicine, The Hospital for Sick Children, Toronto, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Canada; Department of Paediatrics, University of Toronto, Toronto, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0123599PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388348PMC
April 2016

Response to Fuller-Thomson.

Am J Gastroenterol 2015 Sep;110(9):1371-2

Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/ajg.2015.249DOI Listing
September 2015

Strategies to Improve Influenza Vaccination in Pediatric Inflammatory Bowel Disease Through Education and Access.

Inflamm Bowel Dis 2015 Aug;21(8):1761-8

*Department of Pediatrics, University of Ottawa, Ottawa, ON, Canada; †School of Epidemiology, Public Health and Preventative Medicine, University of Ottawa, Ottawa, Canada; ‡Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada; and §CHEO IBD Centre, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada.

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http://pdfs.journals.lww.com/ibdjournal/2015/08000/Strategie
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/MIB.0000000000000425DOI Listing
August 2015

Inflammatory bowel disease in immigrants to Canada and their children: a population-based cohort study.

Am J Gastroenterol 2015 Apr 10;110(4):553-63. Epub 2015 Mar 10.

1] Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada [2] Ottawa Hospital Research Institute, Ottawa, Ontario, Canada [3] Department of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1038/ajg.2015.52DOI Listing
April 2015

Incidence, outcomes, and health services burden of very early onset inflammatory bowel disease.

Gastroenterology 2014 Oct 18;147(4):803-813.e7; quiz e14-5. Epub 2014 Jun 18.

Department of Paediatrics, University of Toronto, Toronto, Canada; SickKids Inflammatory Bowel Disease Center, Division of Gastroenterology Hepatology and Nutrition, Cell Biology Program, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1053/j.gastro.2014.06.023DOI Listing
October 2014

Changing age demographics of inflammatory bowel disease in Ontario, Canada: a population-based cohort study of epidemiology trends.

Inflamm Bowel Dis 2014 Oct;20(10):1761-9

*CHEO Inflammatory Bowel Disease Centre, Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada; †Institute for Clinical Evaluative Sciences, Toronto, ON, Canada; Departments of ‡Pediatrics, §Epidemiology and Community Medicine, and ‖Family Medicine, University of Ottawa, Ottawa, ON, Canada; ¶Ottawa Hospital Research Institute, Ottawa, ON, Canada; **Department of Pediatrics, University of Toronto, Toronto, ON, Canada; ††Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada; ‡‡Department of Medicine, University of Toronto, Toronto, ON, Canada; and §§Mount Sinai Centre for Inflammatory Bowel Disease, Toronto, ON, Canada.

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http://dx.doi.org/10.1097/MIB.0000000000000103DOI Listing
October 2014

Liver enzyme elevations within 3 months of diagnosis of inflammatory bowel disease and likelihood of liver disease.

J Pediatr Gastroenterol Nutr 2014 Sep;59(3):321-3

*Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA †Connecticut Children's Medical Center, Hartford ‡Hasbro Children's Hospital, Providence, RI §I.W.K. Health Center, Halifax, Nova Scotia, Canada ||Hospital for Sick Children, Toronto, Ontario, Canada ¶Goryeb Children's Hospital, Morristown, NJ #Children's Hospital of Wisconsin, Milwaukee **Johns Hopkins Hospital, Baltimore, MD ††Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada ‡‡Children's Medical Center, Dayton, OH §§Riley Hospital for Children, Indianapolis, IN ||||Nationwide Children's Hospital, Columbus, OH ¶¶Children's Hospital of Philadelphia, Philadelphia, PA ##Russell Children's Hospital, Birmingham, AB ***University of Minnesota, Minneapolis †††University of North Carolina, Chapel Hill ‡‡‡Cincinnati Children's Medical Center, Cincinnati, OH §§§Mayo Clinic, Rochester, MN ||||||Penn State Hershey Children's Hospital, Hershey, PA ¶¶¶Cohen Children's Medical Center, New Hyde Park, NY.

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http://dx.doi.org/10.1097/MPG.0000000000000409DOI Listing
September 2014

Validation of international algorithms to identify adults with inflammatory bowel disease in health administrative data from Ontario, Canada.

J Clin Epidemiol 2014 Aug 26;67(8):887-96. Epub 2014 Apr 26.

Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue, Toronto, Ontario, Canada, M4N 3M5; Department of Epidemiology and Community Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5; Ottawa Hospital Research Institute, 725 Parkdale Ave., Ottawa, Ontario, Canada, K1Y 4E9; Department of Family Medicine, University of Ottawa, 451 Smyth Road, Ottawa, Ontario, Canada, K1H 8M5.

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http://dx.doi.org/10.1016/j.jclinepi.2014.02.019DOI Listing
August 2014

Retrospective cohort study of methotrexate use in the treatment of pediatric Crohn's disease.

Inflamm Bowel Dis 2014 Aug;20(8):1341-5

1Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania; 2Department of Pediatrics, Connecticut Children's Medical Center, Hartford, Connecticut; 3Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada; 4Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, ON, Canada; 5Department of Pediatrics, I.W.K. Health Center, Halifax, NS, Canada; 6Pediatric Gastroenterology, Goryeb Children's Hospital, Morristown, New Jersey; 7Department of Pediatrics, Nationwide Children's Hospital, Columbus, Ohio; 8Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania; 9Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin; 10Section of Gastroenterology/Hepatology/Nutrition, Riley Hospital for Children, Indianapolis, Indiana; 11Department of Gastroenterology, Dayton Children's, Dayton, Ohio; 12Division of Pediatric Gastroenterology, Nutrition and Liver Diseases, Hasbro Children's Hospital, Providence, Rhode Island; 13Department of Pediatrics, Russell Children's Hospital, Birmingham, Alabama; 14Division of Pediatric Gastroenterology and Nutrition, Johns Hopkins University School of Medicine, Baltimore, Maryland; 15Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Medical Center, Cincinnati, Ohio; 16Department of Pediatrics, University of North Carolina, Chapel Hill, North Carolina; and 17Department of Pediatrics, Cohen Children's Medical Center, New Hyde Park, New York.

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http://dx.doi.org/10.1097/MIB.0000000000000102DOI Listing
August 2014

Utility of neutrophil Fcγ receptor I (CD64) index as a biomarker for mucosal inflammation in pediatric Crohn's disease.

Inflamm Bowel Dis 2014 Jun;20(6):1037-48

1Department of Pediatrics, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; Divisions of 2Allergy and Immunology and 3Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio; 4Department of Pediatrics, The Children's Hospital of Philadelphia, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; 5Division of Pediatric Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota; 6Division of Pediatric Gastroenterology and Nutrition, Cohen Children's Medical Center of New York, New Hyde Park, New York; 7Department of Pediatric Gastroenterology and Nutrition, Goryeb Children's Hospital/Atlantic Health System, Morristown, New Jersey; 8Division of Pediatric Gastroenterology, Hepatology and Nutrition, Nationwide Children's Hospital, Columbus, Ohio; 9Department of Pediatrics, University of California, San Francisco, San Francisco, California; 10Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada; 11Division of Gastroenterology, Hepatology and Nutrition, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada; 12Digestive Diseases and Nutrition Center, Department of Pediatrics, University at Buffalo, Buffalo, New York; 13Division of Digestive Diseases and Nutrition, Connecticut Children's Medical Center, Hartford, Connecticut; and 14Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Emory University, Atlanta, Georgia.

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http://dx.doi.org/10.1097/MIB.0000000000000049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151275PMC
June 2014

Interactions between the dietary polyunsaturated fatty acid ratio and genetic factors determine susceptibility to pediatric Crohn's disease.

Gastroenterology 2014 Apr 7;146(4):929-31. Epub 2014 Jan 7.

Research Centre, Le Centre Hospitalier Universitaire-Ste-Justine, Montreal, Canada; Department of Pediatrics, University of Montreal, Quebec, Canada. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2013.12.034DOI Listing
April 2014

Ingested soluble CD14 from milk is transferred intact into the blood of newborn rats.

Pediatr Res 2014 Feb 14;75(2):252-8. Epub 2013 Nov 14.

Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Ontario, Canada.

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http://www.nature.com/articles/pr2013225
Publisher Site
http://dx.doi.org/10.1038/pr.2013.225DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4965269PMC
February 2014

Interleukin-6 is associated with steroid resistance and reflects disease activity in severe pediatric ulcerative colitis.

J Crohns Colitis 2013 Dec 20;7(11):916-22. Epub 2013 Jan 20.

Department of Pediatrics, University of Alberta, Edmonton, AB, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.crohns.2012.12.012DOI Listing
December 2013

The role of the environment in the development of pediatric inflammatory bowel disease.

Curr Gastroenterol Rep 2013 Jun;15(6):326

Department of Pediatrics, University of Ottawa, Ottawa, Canada.

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http://dx.doi.org/10.1007/s11894-013-0326-4DOI Listing
June 2013

Alterations in the gut microbiome of children with severe ulcerative colitis.

Inflamm Bowel Dis 2012 Oct 14;18(10):1799-808. Epub 2011 Dec 14.

Department of Pediatric Gastroenterology and Nutrition, University of Southern California, Los Angeles, California 90027, USA.

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http://dx.doi.org/10.1002/ibd.22860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319508PMC
October 2012

NELL1, NCF4, and FAM92B genes are not major susceptibility genes for Crohn's disease in Canadian children and young adults.

Inflamm Bowel Dis 2012 Mar 6;18(3):529-35. Epub 2011 Apr 6.

Department of Pediatrics, University of Montreal, Montreal, Canada; Research Centre, Sainte-Justine Hospital, Montreal, Canada.

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http://dx.doi.org/10.1002/ibd.21708DOI Listing
March 2012

Short-course ondansetron for the prevention of methotrexate-induced nausea in children with Crohn disease.

J Pediatr Gastroenterol Nutr 2011 Oct;53(4):389-93

Department of Pediatrics, University of Ottawa, Ottawa, Canada.

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http://dx.doi.org/10.1097/MPG.0b013e31822855e7DOI Listing
October 2011

Maternal separation and gastrointestinal transit time in neonate rats.

Lab Anim 2011 Oct 9;45(4):280-2. Epub 2011 Aug 9.

Department of Biochemistry, Microbiology and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, ON, K1H 8M5, Canada.

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http://dx.doi.org/10.1258/la.2011.010167DOI Listing
October 2011

C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) or both? A systematic evaluation in pediatric ulcerative colitis.

J Crohns Colitis 2011 Oct 2;5(5):423-9. Epub 2011 Jun 2.

Pediatric Gastroenterology and Nutrition Unit, Shaare Zedek Medical Center, The Hebrew University of Jerusalem, Israel.

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http://dx.doi.org/10.1016/j.crohns.2011.05.003DOI Listing
October 2011

Use of C-reactive protein in children with newly diagnosed inflammatory bowel disease.

J Pediatr 2011 Aug 8;159(2):340-2. Epub 2011 Jun 8.

Department of Pediatrics, University of Ottawa and Children's Hospital of Eastern Ontario Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1016/j.jpeds.2011.04.028DOI Listing
August 2011

Fecal osteoprotegerin may guide the introduction of second-line therapy in hospitalized children with ulcerative colitis.

Inflamm Bowel Dis 2011 Aug 3;17(8):1726-30. Epub 2010 Dec 3.

Division of Digestive Diseases, Hepatology and Nutrition, Connecticut Children's Medical Center, Hartford, Connecticut, USA.

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http://dx.doi.org/10.1002/ibd.21561DOI Listing
August 2011

Solid-food introduction in infants diagnosed as having a cow's-milk protein-induced enterocolitis.

J Pediatr Gastroenterol Nutr 2011 May;52(5):639-43

Division of Gastroenterology, Hepatology and Nutrition, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1097/MPG.0b013e318207ef1aDOI Listing
May 2011

Immediate and long-term outcomes of corticosteroid therapy in pediatric Crohn's disease patients.

Inflamm Bowel Dis 2011 Apr;17(4):954-62

Research Centre, Ste-Justine Hospital, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1002/ibd.21415DOI Listing
April 2011

(14)C radiolabeling of proteins to monitor biodistribution of ingested proteins.

Anal Biochem 2011 Mar 20;410(1):57-61. Epub 2010 Nov 20.

Department of Biochemistry, Microbiology, and Immunology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada K1H 8M5.

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http://dx.doi.org/10.1016/j.ab.2010.11.028DOI Listing
March 2011

Pulse probiotic administration induces repeated small intestinal Muc3 expression in rats.

Pediatr Res 2011 Mar;69(3):206-11

Children's Hospital of Eastern Ontario Research Institute, Ottawa, Ontario K1H 8L1, Canada.

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http://dx.doi.org/10.1203/PDR.0b013e3182096ff0DOI Listing
March 2011

Lactobacillus plantarum 299v Prevents Caspase-Dependent Apoptosis In Vitro.

Probiotics Antimicrob Proteins 2011 Mar;3(1):21-6

Department of Biochemistry, Microbiology and Immunology, University of Ottawa, Ottawa, Canada.

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http://dx.doi.org/10.1007/s12602-011-9066-7DOI Listing
March 2011

Probiotics in inflammatory bowel diseases and associated conditions.

Authors:
David R Mack

Nutrients 2011 02 17;3(2):245-64. Epub 2011 Feb 17.

Children's Hospital of Eastern Ontario, Ottawa, Ontario K1H 8L1, Canada.

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http://dx.doi.org/10.3390/nu3020245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3257670PMC
February 2011

Alpha-lactalbumin in human milk alters the proteolytic degradation of soluble CD14 by forming a complex.

Pediatr Res 2010 Dec;68(6):490-3

Department of Biochemistry, University of Ottawa, Ottawa, Ontario K1H 8M5, Canada.

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http://dx.doi.org/10.1203/PDR.0b013e3181f70f21DOI Listing
December 2010

Comparison of two common outpatient preparations for colonoscopy in children and youth.

Gastroenterol Res Pract 2009 6;2009:518932. Epub 2009 Dec 6.

Department of Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, ON K1H8L1, Canada.

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http://dx.doi.org/10.1155/2009/518932DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2796226PMC
June 2010

Retrospective Evaluation of the Safety and Effect of Adalimumab Therapy (RESEAT) in pediatric Crohn's disease.

Am J Gastroenterol 2009 Dec 1;104(12):3042-9. Epub 2009 Sep 1.

Division of Pediatric Gastroenterology, Goryeb Children's Hospital/Atlantic Health, Morristown, New Jersey 07962 , USA.

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http://dx.doi.org/10.1038/ajg.2009.493DOI Listing
December 2009

Effect of calcium and vitamin D supplementation on bone mineral density in children with inflammatory bowel disease.

J Pediatr Gastroenterol Nutr 2007 Nov;45(5):538-45

Department of Pediatrics, Children's Hospital of Eastern Ontario, University of Ottawa, Ottawa, ON, Canada.

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http://dx.doi.org/10.1097/MPG.0b013e3180dca0ccDOI Listing
November 2007

Probiotics-mixed messages.

Authors:
David R Mack

Can Fam Physician 2005 Nov;51:1455-7, 1462-4

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479485PMC
November 2005

Probiotics and necrotizing enterocolitis.

Authors:
David R Mack

Pediatrics 2005 Jul;116(1):293; author reply 293

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http://dx.doi.org/10.1542/peds.2005-0630DOI Listing
July 2005

D(-)-lactic acid-producing probiotics, D(-)-lactic acidosis and infants.

Authors:
David R Mack

Can J Gastroenterol 2004 Nov;18(11):671-5

University of Ottawa and Children's Hospital of Eastern Ontario, Ottawa, Canada.

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http://dx.doi.org/10.1155/2004/342583DOI Listing
November 2004

Probiotics in relapsing and chronic diarrhea.

J Pediatr Hematol Oncol 2004 Aug;26(8):515-7

Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Canada.

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http://dx.doi.org/10.1097/01.mph.0000133291.11443.a1DOI Listing
August 2004

Role of probiotics in the modulation of intestinal infections and inflammation.

Curr Opin Gastroenterol 2004 Jan;20(1):22-6

Department of Pediatrics, University of Ottawa, and Children's Hospital of Eastern Ontario, Ottawa, Canada.

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http://pdfs.journals.lww.com/co-gastroenterology/2004/01000/
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January 2004

Human serum amyloid A3 peptide enhances intestinal MUC3 expression and inhibits EPEC adherence.

Biochem Biophys Res Commun 2003 Jan;300(2):531-40

Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198, USA.

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http://dx.doi.org/10.1016/s0006-291x(02)02901-7DOI Listing
January 2003

The conserved TFLK motif of mammary-associated serum amyloid A3 is responsible for up-regulation of intestinal MUC3 mucin expression in vitro.

Pediatr Res 2003 Jan;53(1):137-42

Department of Pediatrics, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Ontario, Canada.

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http://www.nature.com/doifinder/10.1203/00006450-200301000-0
Publisher Site
http://dx.doi.org/10.1203/00006450-200301000-00023DOI Listing
January 2003

Shwachman-Diamond syndrome.

Authors:
David R Mack

J Pediatr 2002 Aug;141(2):164-5

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http://dx.doi.org/10.1067/mpd.2002.126918DOI Listing
August 2002

Peripheral blood intracellular cytokine analysis in children newly diagnosed with inflammatory bowel disease.

Pediatr Res 2002 Mar;51(3):328-32

Department of Paediatrics, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, Ontario, Canada, K1H 8L1.

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http://dx.doi.org/10.1203/00006450-200203000-00011DOI Listing
March 2002